Interdisciplinary Center for Chemistry and Biology-Paris CICB

Interdisciplinary Center
for Chemistry and Biology-Paris
CICB - Paris
Federation of Research Laboratories
FR 3567
Teams/Laboratory Units
45 rue des Saints Pères
75006 Paris - France
CAS : Scientific Animation
Committee
tél.: +33 (0)1 42 86 22 22
Frédéric Charbonnier,
Director of CICB-Paris
[email protected]
www.biomedicale.parisdescartes.fr/cicb-paris/
- Crystallography, protein purification and analysis
Pierre Nioche
- NMR
Gildas Bertho
- FACScan
Stéphanie Dupuy
And participate to the organization of the
following Master degrees :
- Biochemistry and Molecular Biology
Céline Tomkiewicz
• Pharmacology, Toxicology, Chemistry, Imaging (MTCI)
• The frontiers of Life
• Bio Sorbonne Paris Cité
- Sensory-motricity
Danping Wang
- Microscopy
Jean-Maurice Petit
CICB-Paris provides training to PhD students
from doctoral schools :
- Animal housing and breeding
Claire Mader
Technological platforms and Core
Facilities
Cafeteria
Conference room
CW : Web site team
- Molecular Modelling
Nicolas Pietrancosta
• Master of Chemistry oriented toward Living
Sciences
- Frontiers in Chemistry track (with Paris
Diderot University)
- Molecular chemistry directed toward Living Sciences track
- Spectroscopy and analysis directed toward
Living Sciences track
- Engeneering of biomolecules track (with Paris Sud University)
• Toxicology
• Pharmacology, specialty: “Integrative Clinical
and Preclinical Pharmacology”
• Master of Biomedical engineering (BME-Paris)
CAS : Scientific Animation
Committee
- Mechanical Stress
François Etienne
CW : Web site team
CICB-Paris research teams also conceive and
elaborate innovative therapeutic tools using
unique synthesis methods. They develop
ultrasensitive biophysical approaches (imaging,
spectroscopy..) and explore biological systems
at the molecular, cellular and tissue levels.
CICB-Paris has approximately 6000 m2 of laboratory space and the research work is supported
by numerous technological resources and core
facilities.
Laboratory Units
Facilities
CICB-Paris takes the advantage of its interdisciplinary context to develop both basic and
applied research in chemistry, biology and at the
interface of these disciplines. The research topics of the teams that compose CICB-Paris deal
with major fields of public health, ranging from
cancer, viral and prion infections to diseases of
the nervous and the articular systems and the
mechanisms of chemical toxicity.
• Pharmacology, Toxicology and Cell Signalling
UMR-S Inserm 1124,
Director : Robert Barouki.
CW
To reach CICB-Paris by public transportation :
Metro : St Germain-des-Prés (line 4)
Mabillon, Sèvres Babylone (line 10)
Rue du Bac (line12)
Bus n° : 39, 63, 68, 69, 70, 84, 86, 87 et 95
• Chemistry & Pharmacological and Toxicological
Biochemistry - UMR CNRS 8601,
Director : Francine Acher.
CAS
CICB-Paris is a federation of 22 research teams
from the CNRS and Inserm and it is composed
of 350 chemists and biologists. It is located
in the center of Paris, at the gates of the Latin
Quarter.
• Cellular Homeostasis and Cancer
UMR-S Inserm 1007,
Director : Evelyne Ségal- Bendirdjian.
Board
What is CICB-Paris
• Personalized Medicine, Pharmacogenomics,
Therapeutical Optimisation
UMR-S Inserm 1147,
Director : Pierre Laurent-Puig.
Management
CICB-Paris / FR3567
Centre Universitaire des Saints Pères
Faculté des Sciences Fondamentales
et Biomédicales
Université Paris Descartes
• Neuroplasticity and Therapies of Addictions
ERL 3649
Director : Florence Noble
Organizational chart of CICB-Paris
Teaching and training
Cell culture lab
1
Research Topics
1 - Innate immunity, inflammation, anti-infectious pharmacology
Innate immunity, inflammation,
anti-infectious pharmacology
• Bio-inorganic Chemistry of Sulphur Species,
Pharmaceutical Chemistry
I. Artaud, D. Padovani, E. Galardon
2 - Toxicology, energy metabolism and
metabolism of xenobiotics
• Mechanism of Interferon Action
and Biotherapeutic Pathways
M. Chelbi-Alix, S. Nisole
3 - Cancer, biomarkers and therapeutic
strategies
4 - Novel approaches at the chemistry-biology
interface, spectroscopy
5 - Physiopathology of nervous and
neuromuscular systems
2
Toxicology, energy metabolism and
metabolism of xenobiotics
• Bio-inorganic Chemistry of Sulphur Species,
Pharmaceutical Chemistry
I. Artaud, J. L. Boucher, P. Dansette,
D. Mansuy, M.-A. Sari
• Pharmacotoxicology and Structural Biology
P. Nioche
• Pharmacology, Toxicology, Cell Signaling of
Cartilage and the Intervertebral Disc
F. Rannou
• Inborn Mitochondrial Diseases : Pharmacological
Therapy and Metabolic Signaling
F. Djouadi, J. Bastin
• Cellular Homeostasis and Cancer
E. Ségal-Bendirdjian, E. Bonnefoy
• Toxicology, Metabolism and Cellular Signaling
X. Coumoul
• Chemistry & Biology, Nucleotides
& Immunology for Therapy
M. Etheve-Quelquejeu, J-P. Herbeuval
• Personalized Medicine, Pharmacogenomics,
Therapeutic Optimization-MEPPOT
P. Laurent-Puig
• New Synthetic Methods for Chemical Biology
L. Micouin
©
3
Cancer, biomarkers and
therapeutic strategies
• Cellular Homeostasis and Cancer
E. Ségal-Bendirdjian, P. Forgez
• Personalized Medicine, Pharmacogenomics,
Therapeutic Optimization-MEPPOT
P. Laurent-Puig
• Pharmacological Chemistry of Receptors and
Transporters of α-aminoacids
F. Acher, I. McCort, N. Pietrancosta
• Signaling and Neurological Pathophysiology
S. Mouillet-Richard
• Neuro-Plasticity and Addiction Therapy
F. Noble
• Mechanism of Interferon Action
and Biotherapeutic Pathways
M. Chelbi-Alix, S. Nisole
• Toxicology, Metabolism and Cellular Signaling
X. Coumoul
• Organic Synthesis for Biomedical Research
Ch. Gravier-Pelletier, G. Prestat
©
3
CBNIT
CBNIT
Cancer, biomarkers and
therapeutic strategies
4
Novel approaches at the
chemistry-biology interface,
spectroscopy
• Chimie & Biologie, Nucléos(t)ides et
Immunologie pour la Thérapie (CBNIT)
M. Etheve-Quelquejeu, J-P. Herbeuval
• Pharmacological Chemistry of Receptors and
Transporters of α-aminoacids
F. Acher, N. Pietrancosta, I. McCort
• Organic Synthesis for Biomedical Research
Ch. Gravier-Pelletier, P. Busca
• Bio-inorganic Chemistry of Sulphur Species,
Pharmaceutical Chemistry
I. Artaud, E. Galardon
• New EPR Spectroscopy and Imaging Markers
for Biomedical Applications
Y. Frapart
• Pharmacotoxicology and Structural Biology
P. Nioche
• Cellular Homeostasis and Cancer
E. Ségal-Bendirdjian, S. Bombard
• NMR : Methodology and Interaction of
Biomolecules
P. Vasos, G. Bertho
• Personalized Medicine, Pharmacogenomics,
Therapeutic Optimization-MEPPOT
P. Laurent-Puig, V. Taly
Vasco Marcato,
Eliette Bonnefoy
©
• Chemistry & Biology, Nucleotides
& Immunology for Therapy
M. Etheve-Quelquejeu, J-P. Herbeuval
• New Synthetic Methods for Chemical Biology
L. Micouin
• Bio-inorganic Supramolecular Chemistry
O. Reinaud
• Organic Synthesis for Biomedical Research
Ch. Gravier-Pelletier, G. Prestat, P. Dalko,
H. Dhimane
5
Physiopathology of nervous and
neuromuscular systems
• Pharmacological Chemistry of Receptors and
Transporters of α-aminoacids
F. Acher, I. McCort, N. Pietrancosta
• Signaling and Neurological Pathophysiology
S. Mouillet-Richard
• New EPR Spectroscopy and Imaging Markers
for Biomedical Applications
Y. Frapart
• NMR : Methodology and Interaction
of Biomolecules
P. Vasos, G. Bertho
©
NMR Platform
Molecular Modelling
Platform
©
• Neuromuscular Degeneration and Plasticity
F. Charbonnier
• Neuro-Plasticity and Addiction Therapy
F. Noble
• New Therapeutic Approaches of Myelination
Ch. Massaad
©
O.Caen, V. Taly
• Stem Cells, Signaling and Prions
O. Kellermann, B. Schneider