Jean-Christophe LEGEAY EDUCATION TRAINING COURSES

Pr Bazureau Laboratory UMR 6226
Université de Rennes 1 - Beaulieu
Avenue du Général Leclerc
35042 Rennes Cedex
(+33) (0)2 23 23 50 11
Jean-Christophe LEGEAY
Current position : Doctorate in Chemistry
Date of birth : 12th June 1979
Nationality : French
Marital Status : Single
Clean driving licence
PROFESSIONAL EXPERIENCE
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1999-2000 : 1) Laboratory technician : analytic chemistry (HPLC, CPG, UV, IR, ) GlaxoSmithkline
(Mayenne, France).
2) Laboratory technician : formulation of manure for industrial applications. CBB
Développement (Rennes, France).
TRAINING COURSES
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January to March 2002 : Enzymatic catalysis : synthesis of retinol esters for cosmetologic applications.
(CBB Développement, Rennes, France).
April to June 1999 : HPLC control of various drug (GlaxoSmithkline, Mayenne, France).
EDUCATION
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2003-2006 : Ph.D in Organic Chemistry (financial support by the French Ministery of the Education
and the Research).
Laboratory of Pr. J.P. Bazureau, ICMV UMR CNRS 6226, University of Rennes 1, France.
Topic : Ionic liquid phase synthesis for combinatory chemistry (microwave, multicomponent and
multisteps reactions).
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2002-2003 : Post Graduate Certificate in Organic Chemistry (Ranking : 4, 15.19/20, with mention).
Laboratory of Dr. B. Bujoli, Organic Synthesis Laboratory, University of Nantes, France.
Research Advisor : Dr. B. Bujoli and Dr. P. Janvier
Topic : Synthesis of P,N-ligands and catalysis applications.
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2000-2002 : French Maîtrise de Science et Technique de Chimie Organique, option Chimie Médicinale.
University of Le Havre, France. (equivalent to Master’s in Organic Chemistry with the option in Drug
Chemistry).
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1997-1999 : 2-years Diploma from University Institute of Technology of Rennes 1.
TEACHING EXPERIENCE
Laboratories Tutoring for Undergraduate Students in analytic chemistry (40 hours).
Laboratories Tutoring for Undergraduate Students in informatic (Excel, Powerpoint) (60 hours).
TECHNIQUES AND SKILLS
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Catalysis, preparation of transition metal complexes and study of their catalytic properties.
Microwave chemistry : heterocycle synthesis under microwave irradiation.
Supported synthesis : ionic liquid phase synthesis supporting various heterocycle.
Spectroscopic techniques : NMR (1H, 13C, 31P) (1D, 2D), SM, IR, UV.
Chromatographic techniques : GC and HPLC.
COMPUTER SKILLS
Software : Word, Excel, Powerpoint, Adobe, ChemOffice,Chemsketch, Mestrec-C, Win-NMR .
Database : Science Finder, Beilsten.
LANGUAGES
French : native language.
English : working knowledge
German : basic
PUBLICATIONS AND COMMUNICATIONS
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Research publication :
A new Approach to N-3 Functionnalized 3,4-Dihydropyrimidine-2(1H)-ones with 1,2,4Oxadiazole group as Amide Isostere via Ionic Liquid Phase Technology.
Legeay, J.C.; Vanden Eynde, J.J.; Toupet, L.; Bazureau, J.P. submitted to Tetrahedron Lett 2006
Task-Specific Ionic Liquid Technology Applied to the Synthesis of Biginelli 3,4dihydropyrimidine-2(1H)-ones : A Three-Component Condensation Protocol Based on Ionic
Liquid Phase Bound Acetoacetate.
Legeay, J.C.; Vanden Eynde, J.J.; Toupet, L.; Bazureau, J.P. ARKIVOC 2007, 3, 13.
Liquid-Phase Traceless Synthesis of Polyhydroquinoline using Task-Specific Ionic Liquid
Technology.
Legeay, J.C.; Goujon, J.Y.; Vanden Eynde, J.J.; Toupet, L.; Bazureau, J.P. J. Comb. Chem. 2006 ASAP
Ionic Liquid Phase Technology : A New Tool for Combinatorial Chemistry. Applications in
Heterocyclic Chemistry Mediated by Microwave Dielectric Heating.
Bazureau J.P., Legeay J.C., Fraga-Dubreuil J., Hakkou H.
2-volume Proceedings of III International Conference on the Chemistry and Biological Activity of
Nitrogen-Containing Heterocycles, 16-19 May 2006, 1, 203 Moscow (Russia).
Ionic Liquid Phase technology supported the three component synthesis of Hantzsch 1,4dihydropyridines and Biginelli 3,4-dihydropyrimidin-2(1H)-ones under microwave dielectric
heating.
Legeay, J.C.; Vanden Eynde, J.J.; Bazureau, J.P. Tetrahedron 2005, 61, 12386.
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Oral presentations :
Ionic Liquid Phase Technology : A New Tool for Combinatorial Chemistry. Applications in
Heterocyclic Chemistry Mediated by Microwave Dielectric Heating.
Legeay, J.C., Bazureau, J.P. III International Conference on the Chemistry and Biological Activity of
Nitrogen-Containing Heterocycles, May 2006, Moscow (Russia).
Synthèse multiétapes sur phases liquides ioniques : analogues de composés d’intérêts biologiques
(3,4-dihydropyrimidines, 1,4-dihydropyridines et pyridines)
Legeay, J.C.; Vanden Eynde, J.J.; Bazureau, J.P. Société Française de Chimie (SFC), section Bretagne
Pays de la Loire, Batz sur mer 23-25 mai 2005.
Synthèse de 1,4-dihydropyridines (DHPs) et Pyridines supportées sur phase liquide ionique &
sous irradiation micro-onde.
Legeay, J.C.; Vanden Eynde, J.J.; Bazureau, J.P. XIIIèmes conférences européennes du groupement des
pharmacochimistes de l’arc atlantique (GP2A), Rennes 16, 17 septembre 2004.
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Poster communication :
Ionic liquid phase technology applied to the synthesis of a small library of 1,4-dihydropyridines
and pyridines-3,5-dicarboxylate
Legeay, J.C.; Bazureau, J.P.
1st International Congress on ionic Liquids (COIL), Salzburgn Austria, June 19- 22, 2005.
Synthesis of novel N,N and P,N chiral ligands. Precursors of asymmetrical biphasic catalysts.
Nonglaton, G.; Roussière, H.; Maillet, C.; Legeay, J.C.; Evain, M.; Janvier, P.; Bujoli, B. Sigma-aldrich
Jeunes chercheurs (Young researchers) (SAJEC) 2004, October 2004, Dijon, France
Synthèse de 1-4 Dihydropyridines (DHPs) et Pyridines supportées sur phase liquide ionique &
sous irradiation micro-onde,
Legeay, J.C.; Vanden Eynde, J.J.; Bazureau, J.P. XIIIèmes conférences européennes du groupement des
pharmacochimistes de l’arc atlantique (GP2A), Rennes 16, 17 septembre 2004.
REFERENCES
Pr. Jean-Pierre Bazureau
ICMV, Sciences Chimiques de Rennes, UMR 6226, Université de
Rennes1, France.
Phone : (+ 33)22323-6603
Email : [email protected]
Pr. Jack Hamelin
ICMV, Sciences Chimiques de Rennes, UMR 6226, Université de
Rennes1, France.
Phone : (+ 33)22323-6278
Email : [email protected]
Dr. Vanden Eynde
Institut de Chimie, Université de Mons Hainaut, Belgium
Phone : 065/37.33.37
Email : [email protected]