epidemiologie de l`infection a herpesvirus humain type 8 au senegal
Transcription
epidemiologie de l`infection a herpesvirus humain type 8 au senegal
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D E7 4 0 2 E1 2 EE DEDICACE A mes parents qui n’ont ménagé aucun effort pour mon éducation, pour leur soutien et leur réconfort dans les moments difficiles et pour leur direction bienveillante. Les mots me manquent pour vous témoigner ma reconnaissance. Puissiez-vous trouver dans ce travail l’expression de ma profonde gratitude A mes grands parents dont je garde encore le nostalgique souvenir de la chaleureuse affection. A mes petits frères et sœur Alvarès, M’bor, Nicolas, Guilène et Daniel Soyez assurés de ma profonde affection, puissiez-vous trouver dans le travail de l’aîné que je suis la motivation de faire beaucoup mieux. A ma sœur Elisabeth Ma reconnaisance pour tes conseils avisés et ton édifiante direction. A ma sœur Marie-Louise, mes frères Das, N’diouga, Pierre Soyez assurés de mon amour fraternel et de mon attachement A mes oncles et mes tantes Ma reconnaissance pour vos conseils et votre soutien A mes neveux et niéces, Oumar, Samuel, Seynabou, Awa, Sally, Momar Ngary, Djanor Santé, longue vie et réussite A Marianne Ndiaye et Clarisse Monnet Votre exemple m’a inspiré, merci pour votre soutien. A mes amis Bamba, Auguste, Edouard Pour l’amitié qui nous lie. Au Pr Cheikh-Saad BOYE, Pour sa disponibilité. Au Dr Ndeye Coumba TOURE-KANE Pour votre direction et vos sages conseils, mes sincères remerciements. A tous mes amis et collègues du Laboratoire de Bactériologie-Virologie Magueye SENE, Halimatou DIOP-NDIAYE, Ibrahima DIAGNE, Fabien Niama, Ambroise AHOUIDI, Maguette DIOP, Fatou SECK, Amy TOURE, Diakité, Djibril SAMBOU, Michel, Oumar SAGNA, Badji, Codou, Madame NDOYE, Major Codou, Sira SIDIBE, Coumba, Awa Cheikh, Ouly, Astou, El hadj, Bara, Farba, Renée, NIANG-DIALLO,Fatou SYLLA, Assane FAYE et Silman DIAWARA. au contact desquels j’ai appris l’esprit d’équipe. Au Dr Astou GUEYE-NDIAYE 7 Pour sa disponibilité A toute l’équipe du Laboratoire de Biochimie de l’Etablissement Public de Santé Aristide le Dantec A toute l’équipe du Laboratoire de Biologie de l’Hôpital Albert Royer particulièrement au Major DIENG, Maïmouna THIAM, Moussa, Sonko. Au Dr Gaston SARR, Pour sa disponibilité A tous mes maîtres du primaire à la Faculté. A tous mes camarades de promotion, Beaucoup de chance Au Parent Inconnu, Toutes ces personnes qui œuvrent de façon bienveillante à ma réalisation. A notre Maître et directeur de thèse Madame Aïssatou GAYE-DIALLO, Maître de Conférence Agrégé Vous nous avez guidé tout au long de ce travail qui porte votre empreinte indélébile. Les années passées à vos côtés nous ont permis d’apprécier vos qualités humaines et professionnelles. Votre rigueur et votre générosité nous ont particulièrement marquées. Veuillez accepter, chère maître, l’expression de notre profonde gratitude et notre indéfectible attachement. A notre codirecteur de thèse Docteur Ndeye Coumba TOURE-KANE Les mots ne suffiraient pas pour exprimer toute notre reconnaissance. Vous avez participé de façon décisive à ce travail. Vos conseils nous ont été très bénéfiques. Votre sens élevé des rapports humains, votre amour du travail bien fait, votre disponibilité vous assurent l’estime de tous. Recevez nos plus vifs remerciements. A Notre Maitre et Président de Jury, Monsieur le Professeur Souleymane MBOUP Nous avons eu le privilège de bénéficier de votre enseignement de haute qualité et de vos sages conseils. Vos qualités humaines et professionnelles sont exceptionnelles. Vos qualités scientifiques font honneur à notre Faculté, à notre pays et à l’Afrique. Acceptez tous nos remerciements et notre profonde reconnaissance. A notre Maître et Juge Monsieur le Professeur Moussa Fafa Cissé C’est pour nous un réel honneur de vous compter parmi les membres de ce jury. Vos qualités intellectuelles et votre sympathie font de vous un professeur distingué. Nous vous remercions d’avoir accepté de juger ce travail. A notre Maître et Juge Monsieur le Professeur Salif Sow Nous avons beaucoup admiré votre rigueur, vos compétences professionnelles et votre 4 courtoisie. Votre présence dans notre jury nous donne l’occasion de vous témoigner notre admiration et notre profond respect. 1 A (%#- (%#- Louange à Toi, YAH Dieu le Père Tout-Puissant par qui toutes choses sont. Merci pour ce travail que Tu as permis. Puisses-Tu dans Ta Bienveillante Toute-Puissance le bénir et m’accorder Ta direction pour que j’arrive à la glorieuse Lumière de la Connaissance. Puisses-Tu faire de moi Joseph, celui que Tu accrois et m’accorder beaucoup de Providence. Par Jésus le Christ Notre Seigneur. Amen E > M@"8%! @!'(% ," J 3()% (""$ " 8%! ( *% (! (* ' ) (" % ! 8%! &!% (""(% S $( /('%$$ ) M ! 8%! )* !8 "( @(0 * $$D 766A 5678 )( $ $% )! (* ' ) (" % %)%/%*(% #( ! ( #% $ 0% ' $*!$(%D "!% ) '#! !) ' $*!$(% "'% )M( *% * 8%! (! (* ' ) (" % %$$' '(% (!% S )M(! (//*% !' ($ * '' $( '($()% ) ($'( K@,""$(% 0(0$% (% (0% / $$%*!$(%L $ $,'"@ ' )%//! ) ! $ ',$ ' '!$%"$D M"%)'% $ 0% ) $M%/*% S "8%! @!'(% ," J (#$% "( $ ) ! $( "8($* T $( "$!"( ) * !) 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J *@U $ K27E(L `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