th17-derived cytokines : new kids in the block of inflammation

MEETING GREMI 2008
TH17-DERIVED CYTOKINES :
NEW KIDS ON THE BLOCK OF INFLAMMATION
December, 12th, 2008; Institut Pasteur, Paris, France
Organizing Committee : V. Witko-Sarsat, N. Vergnolle, J.F. Savouret
X. Norel, V. Lagente, M. Chignard, M. Si Tahar
8:30-9:25
Welcome of the participants
9:25-9:30
Message by Michel Chignard, President of Gremi
Session 1
Chairpersons : N. Vergnolle (Inserm U563, Toulouse, France)
P. Miossec (Hôpital de Lyon-Biomérieux, Lyon France)
9:30-10:00
P. Miossec (Hôpital de Lyon-Biomérieux, Lyon, France)
IL-17 and Th17 in chronic inflammation
10:00-10:30
Selected oral communications
H-D. Chang (DRFZ, Berlin, Germany)
Th memory for interleukin-17 expression is stable in vivo
K. McNamee (Imperial College London, UK)
Mechanisms of IL-17-induced hyperalgesia
10:30-11:15
Coffee break - Posters – Exhibition
Session 2
Chairpersons : B. Stockinger (MRC, London, UK)
J.-F. Savouret (Inserm UMR 747, Paris, France)
11:15-11:45
G. Eberl (Institut Pasteur, Paris, France)
In vivo equilibrium of pro-inflammatory and regulatory RORγt+ T
cells
11:45-12:15
Selected oral communications
I. de Bock (Université Libre de Bruxelles, Belgium)
Inhibition of Th2 skewed response in neonates promotes the
development of Th17 type effector T cells
R. Williams (Imperial College, London, UK)
Blockade of TNF in collagen-induced arthritis reveals a novel
immunoregulatory pathway for Th1 and Th17 cells
12:15-12:45
B. Stockinger (MRC National Institute for Medical Research, London,
U.K.)
Modulation of Th17 development and function by environmental
toxins
12:45-14:45
Lunch - Posters – Exhibition
Session 3
Chairpersons : V. Witko-Sarsat (Inserm U845, Paris, France)
M. A. Cassatella (Verona University, Italy)
14:45-15:15
M.A. Cassatella (Verona University, Italy)
Do neutrophils and Th17 cells cross-talk ?
15:15-15:30
Selected oral communication
G. Sellge (Institut Pasteur, Paris, France)
Th17 cells are the dominant T cell subtype primed by Shigella flexnerimediating protective immunity upon re-infection
15:30-16:00
M. Leite de Moraes (Hôpital Necker, Paris, France)
Biology and functions of IL-17-producing invariant NKT (iNKT17)
cells
16:00-16:45
Coffee break - Posters – Exhibition
Session 4
Chairpersons : M. Si-Tahar (Institut Pasteur, Inserm U874, Paris, France)
B. Ryffel (CNRS UMR6218, Orléans, France)
16:45-17:15
B. Ryffel (CNRS UMR6218, Orléans, France)
Injury-induced lung inflammation and the role of Th17 cells
17:15-17:30
Selected oral communication
F. Novelli (University of Turin, Italy)
Autoreactive T helper 17 lymphocytes are expanded in multiple
sclerosis and inhibited by type I interferon
17:30-18:00
R. Kolbeck (MedImmune, Inc., Gaithersburg, U.S.A.)
Modulation of Th17 function for the treatment of autoimmune
diseases
18:00-18:05
Closing Remarks