neurosciences - fondation ipsen
Transcription
neurosciences - fondation ipsen
Registration Form Paris - May 5, 2014 Family name / Nom ...................................................................................... First name / Prénom....................................................................................... Speciality / Spécialité...................................................................................... Department or Unit / Service ou Laboratoire.................................... .................................................................................................................................... .................................................................................................................................... Affiliation / Affiliation (Hôpital, Inserm, CNRS, etc).............................. .................................................................................................................................... .................................................................................................................................... Street and N° / N° et Rue............................................................................ Area code / Code postal............................................................................... City / Ville.............................................................................................................. Country / Pays.................................................................................................... Telephone / Téléphone ................................................................................. E-mail..................................................................................................................... .................................................................................................................................... Registration Fee / Frais d’inscription 100 € before April 1, 2014 130 € after April 1, 2014 Including lunch, coffee-breaks, congress bag, proceedings. Comprenant déjeuner, pauses-café, kit congrès, compte-rendu. Free for students but : - Registration is compulsory and should be completed on March 15th at the latest. Registration will be confirmed according to avaibility on April 1st. - Due to space restrictions, lunch for students is sujected to avaibility. Student / Étudiant Payment / Mode de règlement - Cheque should be made out to ‘Fondation IPSEN/ Fondation de France’ - For foreigners, payment on site will be accepted (cash only, no credit card please). Date......................................................................................................................... Signature : 65, quai Georges Gorse - 92650 Boulogne-Billancourt cedex - France Tél. : +33 (0)1 58 33 50 00 – Fax : +33 (0)1 58 33 50 01 www.fondation-ipsen.org neurosciences 2004 Genotype – proteotype – phenotype correlations in dementia 2006 Alzheimer: 100 years and beyond 1990 1991 1992 1993 1994 1995 1996 1997 1998 2000 2001 2003 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 (in collaboration with Tübingen University) 2007 2008 2009 2010 2011 2012 Synaptic plasticity and the mechanism of Alzheimer’s disease Intracellular traffic and neurodegenerative disorders Diabetes, insulin and Alzheimer’s disease Two faces of evil: Cancer and neurodegeneration Protein quality control in neurodegenerative diseases Proteopathic seeds and neurodegenerative diseases Glutamate, cell death and memory Gene transfer and therapy in the nervous system Motor and cognitive functions of the prefrontal cortex Temporal coding Neurobiology of decision-making Isolation, characterization and utilization of CNS stem cells Normal and abnormal development of the cortex Neuroplasticity: Building a bridge from the laboratory to the clinic Neuroimmune interactions and neuropsychiatric diseases Neuronal death: By accident or by design Neurosciences at the post-genomic era Stem cells in the nervous system: Function and clinical implications Neurobiology of human values Memories: Molecules and circuits Retrotransposition, diversity & the brain Neurobiology of «Umwelt»: How living beings perceive the world Macro-roles for micrornas in the life and death of neurons Characterizing consciousness: From cognition to the clinic? Epigenetics, brain and behavior Programmed cells : From basic neuroscience to therapy New frontiers in social neuroscience Micro-, meso- and macro-connectomics of the brain alzheimer’s disease consciousness cognition synapses memory epigenesis network genome decision-making micro-RNA mind anmesia plasticity apoptosis LTP stem cells axone neuronal grafting cortex brain mapping anmesia decade of the brain cognition epigenesis network decision-making mind synapses axone memory epigenesis genome neuronal grafting plasticity anmesia apoptosis stem cells brain mapping LTP decade of the brain cortex stem cells consciousness anmesia mind epigenesis network synapses decision-making endocrinology micro-RNA 2002 Brain somatic cross-talk and the central control of metabolism 2002 Endocrine aspects of successful aging: Of genes, hormones and lifestyles 2003 Hormones and the brain 2004 Deciphering growth 2005 Insights into receptor function and new drug development targets 2006 Hormonal control of cell cycle 2007 Hormones and social behavior 2008 IGFs: Local repair and survival factors throughout life-span 2009 Novel insights in adipose cell functions 2010 Multi-system endocrine disruption 2011 Multiple origins of sex differences in brain. Neuroendocrine functions and their pathologies 2012 Hormones, intrauterine health and programming 2013 Brain crosstalk in puberty and adolescence Micro-, meso- and macroconnectomics of the brain cancer science 1987 Immunological aspects of Alzheimer’s disease and brain amyloidosis 1988 Genetics and Alzheimer’s disease 1988 Neuronal grafting and Alzheimer’s disease: Future perspectives 1989 Biological markers of Alzheimer’s disease 1989 Imaging, cerebral topography and Alzheimer’s disease 1990 Growth factors and Alzheimer’s disease 1991 Neurophilosophy and Alzheimer’s disease 1992 Heterogeneity of Alzheimer’s disease 1993 The ß-amyloid protein precursors in development, aging and Alzheimer’s disease 1994 Alzheimer’s disease: Lessons from cell biology 1995 Apolipoprotein E and Alzheimer’s disease 1996 Connections, cognition and Alzheimer’s disease 1997 Presenilins and Alzheimer’s disease 1998 Epidemiology of Alzheimer’s disease: From gene to prevention 1999 Fatal attractions within neurons: Intracytoplasmic protein aggregates in Alzheimer’s disease and reated neurodegenerative disorders 2000 Neurodegenerative diseases: Loss of function through gain of function 2001 Notch from neurodevelopment to neurodegeneration: keeping the fate 2002 Immunization against Alzheimer’s and other neurodegenerative diseases 2003 The living brain and Alzheimer’s disease 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 Can cancer be treated as a chronic disease? Are inflammation and cancer linked? Metastasis and invasion Metabolism and cancer Molecular targets of cancer therapy Stem cells and cancer Epigenetics and cancer Mouse models of human cancer: Are they relevant? Cancer immunotherapy Cancer genomics Micro-, meso- et macro- connectomiques cérébrales Paris - May 5, 2014 vascular tree 2004 2005 2006 2007 2008 Origins and regenation of the vascular tree Life and death of the vascular tree The vascular tree aflame! Angiogenesis and neurogenesis Oxygen sensing in the vascular tree longevity 1996 Longevity: To the limits and beyond 1998 The paradoxes of longevity 1999 Sex and longevity: sexuality, gender, reproduction, parenthood 2001 Brain and longevity 2004 Frailty and longevity LTP neurosciences 2FI0179- Design : Alain Compans Micro-, meso- and macro- connectomics of the brain COLLOQUES MÉDECINE ET RECHERCHE 2FI0179- Design : Alain Compans To be returned to the Fondation IPSEN with the registration fee À retourner avec les droits d’inscription à la Fondation IPSEN Colloques Médecine et Recherche Program Micro-, meso- and macro- connectomics of the brain Scientific Committee: Henry Kennedy (Inserm U846, Bron, France) David C. van Essen (Washington University School of Medicine, St Louis, USA) Yves Christen (Fondation IPSEN, Paris, France) Paris - May 5, 2014 Biological brains are extraordinarily complex devices for processing information and controlling behavior. Recent advances in systematically characterizing brain circuitry at different spatial scales offer exciting prospects for deepening our understanding of brain function in humans and in a diversity of animal models. This Colloque Médecine et Recherche will bring together leading investigators who work in the new arena of brain connectomics. This includes ‘macro-connectome’ efforts to comprehensively chart long-distance pathways and functional networks; ‘micro-connectome’ efforts to identify every neuron, axon, dendrite, synapse, and glial process within restricted brain regions; and ‘meso-connectome’ efforts to systematically map both local and long-distance connections using anatomical tracers. Presentations will highlight cutting-edge methods that can accelerate progress in elucidating static ‘hard-wired’ circuits of the brain as well as dynamic interactions that are vital for brain function. The power of connectomic approaches in characterizing abnormal circuits in the many brain disorders that afflict humankind will be considered. Experts in computational neuroscience and network theory will provide perspectives needed for synthesizing across different scales in space and time. Altogether, this symposium will provide an integrated view of the challenges and opportunities in deciphering brain circuits in health and disease. Les cerveaux biologiques constituent des dispositifs extraordinairement complexes permettant le traitement de l’information et le contrôle du comportement. Des progrès récents relatifs à la caractérisation systématique de la circuiterie cérébrale, à différentes échelles spatiales, débouchent sur des perspectives fascinantes permettant d’approfondir notre connaissance des fonctions du cerveau des hommes et de divers modèles animaux. Ce Colloque Médecine et Recherche rassemble des chercheurs leaders dans ce nouveau domaine qu’est la connectomique cérébrale. Ceci inclut les travaux sur le macro-connectome visant à comprendre la cartographie des voies neuronales à longue distance et les réseaux fonctionnels ; ceux sur le microconnectome afin d’identifier chaque neurone, axone, dendrite, synapse, processus glial, au sein de régions cérébrales limitées ; et ceux sur le méso-connectome afin de cartographier systématiquement les connexions, à la fois locales et à longue distance, en utilisant des traceurs anatomiques. Les intervenants présenteront les méthodes d’avant-garde qui permettent un progrès accéléré des connaissances des circuits câblés de façon statique aussi bien que des interactions dynamiques vitales pour les fonctions cérébrales. L’intérêt des approches connectomiques pour caractériser les circuits présentant des anomalies liées à plusieurs pathologies cérébrales affectant le genre humain sera également envisagé. Des experts en neuroscience computationnelle et de la théorie des réseaux apporteront les perspectives nécessaires à la synthèse des données sur les différentes échelles de temps et d’espace. Ce Colloque Médecine et Recherche est en définitive destiné à fournir une vue intégrée des défis et des opportunités que nous offre le décodage des circuits cérébraux normaux et en situation pathologique. Fondation IPSEN sous l’égide de la Fondation de France Information egistration: R Centre de Conférences et de Réceptions Etoile St-Honoré 21-25 rue Balzac - 75008 Paris, France Organization / Organisation Fondation IPSEN Sonia Le Cornec 65, quai Georges Gorse 92650 Boulogne-Billancourt Cedex France Tél. : +33 (0)1 58 33 50 00 [email protected] Venue / Lieu 8:30 am Yves Christen: Welcoming remarks SESSION 1 8:45 am Terrence J. Sejnowski (Salk Institute for Biological Studies, La Jolla, USA) Nanoconnectomics 9:15 am Cori Bargmann (The Rockefeller University, New York, USA) Fixed circuits and flexible behaviors in C. elegans 9:45 am Winfried Denk (Max Planck Institute for Medical Research, Heidelberg, Germany) Structural neurobiology 10:15 am Posters and coffee break 10:45 am Edward M. Callaway (Salk Institute for Biological Studies, La Jolla, USA) Molecular, genetic, viral and optical approaches for linking neural ciruits to brain function 11:15 am Karl Deisseroth (Stanford University, Stanford, USA) Optical deconstruction of fully-assembled biological systems 11:45 am Andreas Burkhalter (Washington University School of Medicine, St Louis, USA) Connecting the network of mouse visual cortex to behavior 12:15 pm Henry Kennedy (Inserm U846, Bron, France) The densely connected cortex 12:45 pm Lunch and posters SESSION 2 2:00 pm Wim Vanduffel (Massachussetts General Hospital, Charlestown, USA) Title to be provided 2:30 pm David C. van Essen (Washington University School of Medicine, St Louis, USA) The human connectome project 3:00 pm Olaf Sporns (Indiana University, Bloomington, USA) Connectome networks - from cells to systems 3:30 pm Posters and coffee break 4:00 pm Kevan Martin (University of Zurich, Zurich, Switzerland)) How to survive without a connectome 4:30 pm Nathalie Tzourio-Mazoyer (Université de Bordeaux Segalen, Bordeaux, France) Intra- and inter-hemispheric connectivity supporting hemispheric specialization 5:00 pm Paul Thompson (UCLA School of Medicine, Los Angeles, USA) Genetics of the connectome and the ENIGMA project 5:30 pm Conclusion Centre de Conférences et de Réceptions Etoile St-Honoré 21-25 rue Balzac 75008 Paris France Parking public Etoile Friedland à 150 mètres Métro : Charles de Gaulle Etoile (lignes 1, 2 et 6) et RER A Official language / Langue officielle English / Anglais Posters / Communications affichées Abstracts for posters should be submitted before April 1, 2014 [email protected] Les abstracts des posters doivent être soumis d’ici le 1er Avril 2014 [email protected] Lunch / Déjeuner Served on site / Servi sur place Accommodation / Hôtel You will receive, along with your registration receipt, a list of hotels located close to the venue of the meeting. Vous recevrez, avec votre accusé d’inscription, une liste d’hôtels proches du lieu de la réunion. 65, quai Georges Gorse - 92650 Boulogne-Billancourt cedex - France Tél. : +33 (0)1 58 33 50 00 – Fax : +33 (0)1 58 33 50 01 www.fondation-ipsen.org