2 3 1 - INAF - Université Laval
Transcription
2 3 1 - INAF - Université Laval
INAF A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 Table of contents A word from the Director . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 INAF in 2005-2006 The Organization . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 Board of Directors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 INAF Members . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 Science enhancing nutrition The research program . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 Productivity at a glance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9 Main research themes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10 Research Chairs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 Studying at INAF, taking the path to success . . . . . . . . . . . . . . . . . . . . . . . . . . 13 STELA Centre [Dairy research] . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14 Plant products research group . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16 Strategic development . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18 Events A bounty year for knowledge transfer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20 Nutra-Innovation Network . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22 Lectures and seminars . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 24 Partner organizations and companies . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25 Appendices Research Projects . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Publications . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Communications . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Student projects . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Translation from French to English: Stephen J. Davids, Ph.D., Sensiculture Inc. Design and layout: Isabelle Jobin graphiste 28 40 47 56 A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 INAF A word from the Director This report provides an overview of INAF’s activities showing impressive productivity for 2005-2006, thanks to the immense talent and tireless effort of its researchers, professional support staff and graduate students. Upon reading this document, you will also discover the numerous achievements for the year in terms of organizational development, scientific presentations and outreach. It was during 2005-2006 that INAF directors completed a vast consultation that led to the filing of its new five-year plan of action. INAF has also undertaken new actions and new strategic partnerships to maximize the benefits accruing from its achievements in terms of development and transfer of knowledge and technology. As an example of this, let us cite the development of a major research project on cheese technology and type characterization in partnership with several businesses in the dairy sector, the launching of the “Health Nutrition Clinic” and participation in the creation of the Association for Health Ingredients in Foods. Among the researchers, aligning INAF and STELA (dairy science and technology research centre) memberships has affirmed the importance of the dairy sector in the scientific program of INAF. Three new researchers have joined the ranks of INAF as associate members. From Université Laval, Dr. Steve Labrie has been recruited through the industrial research chair on cheese technology and type characterization and Dr. Claude Robert, animal nutrigenomics researcher, is joining us from the department of animal sciences. From TransBIOTech in Lévis, we welcome pharmacodynamics researcher Esther Millette and finally Daniel St-Gelais, cheese technology researcher at the Agriculture and Agri-Food Canada research centre in St. Hyacinthe. The group has also recruited new personnel for coordination of the scientific platforms, technology transfer, networking and administration. Research activities, supported by a budget of over $10M from Quebec and Canadian granting agencies as well as industrial partners, have allowed major scientific advances, which have been communicated to peers and users through numerous publications and scientific gatherings. Training of graduate students has reached a new peak at INAF, with over 300 Masters and doctoral students plus post-docs carrying out research within the framework of the scientific program at INAF. The year was also distinguished by exceptional outreach and increased recognition of INAF and its activities on the national and international scale, due especially to the number and significance of the events organized throughout the year for its researchers as well as for industry and the general public. As a final thought, we may now proudly say that INAF has become a model for research and training in Quebec. Its members’ sense of attachment has been crucial to maintaining this status. I therefore warmly encourage our researchers to continue to make INAF shine in all their research, training and transfer activities and I reiterate our standing invitation to them to contact us for assistance with any research project or strategic partnership development in the high priority fields of food and agriculture, nutrition and health. Benoît Lamarche Director 1 INAF A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 INAF in 2005-2006 Organization Vision INAF will be recognized nationally as a leader in research and training in the fields of functional foods, nutrition and health and will make its presence felt on the international scene before the end of the current decade. Mission INAF research group values Organization INAF is a multi-disciplinary grouping of recognized scientists working in synergy on advancing knowledge in the area of human nutrition and its repercussions on health. The mission of INAF is rooted in the achievement of three main goals: Achievement of all research, training and knowledge transfer objectives must bear the stamp of the following values: The Institute of Nutraceuticals and Functional Foods (INAF) is the largest network of researchers in Canada devoted entirely to the study of the complex interactions between foods and their components, nutrition and health. INAF is developing an innovative multidisciplinary research program intended to promote the development of safe and efficacious food products for improving health and preventing chronic diseases. • Improving human nutrition by developing fundamental and applied knowledge of foods and of functionally significant molecules; • Contributing to the training of highly qualified personnel; • Rigorous science and ethics; • Excellence in research and quality of training; • Sharing of resources and knowledge; • Conviviality and open-mindedness; • Action stemming from the health and economic needs of society. • Ensuring the transfer of knowledge and of technologies to industry, health professionals and the general public. Created at Université Laval in 1999, INAF is the fruit of an audacious initiative of a dozen researchers from the Faculty of agriculture and food science. Since then, INAF has become a highly competitive research group, now comprising a total of 42 regular members and 19 associate members from Quebec research institutions recognized throughout Canada. INAF is proud to be able to count on the financial support of Université Laval and the Faculty of agriculture and food science, and on a major contribution from the Fonds québécois de recherche sur la nature et les technologies (FQRNT) granted within the Strategic Groupings Program – Research Centres Category. The following is a list of the research institutions part of the INAF network: Université Laval Université de Montréal Agriculture and Agri-Food Canada Université de Sherbrooke CÉPROCQ (Cégep de Maisonneuve) Université du Québec à Montréal INRS-Institut Armand-Frappier McGill University TransBIOTech (Cégep de Lévis-Lauzon) 2 A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 INAF INAF in 2005-2006 Board of Directors Benoît LAMARCHE Yves POULIOT Renée MICHAUD Director Université Laval Scientific director Université Laval Deputy director Université Laval Denis ROY Laurent BAZINET André MARETTE Charles RAMASSAMY Coordinator of research theme 1 Université Laval Coordinator of research theme 2 Université Laval Coordinator of research theme 3 Université Laval Representing researchers from institutions other than Université Laval INRS-Institut Armand-Frappier Sylvie TURGEON Yves DESJARDINS Julie PAQUIN Director of the STELA centre (Dairy research group) Université Laval Academic program director Coordinator of the plant products research group Université Laval Masters student Representative of student and post-doctoral researchers Université Laval direction 3 INAF A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 INAF in 2005-2006 members Members REGULAR THEME 1 MEMBERS Identification, characterization and functionality of bioactive molecules Paul ANGERS* Analytical and food chemistry, bioactive lipids Department of food sciences and nutrition, FSAA Université Laval Edward FARNWORTH Nutrition and metabolism, probiotics Food Research and Development Centre (Saint-Hyacinthe), Agriculture and Agri-Food Canada Gisèle LAPOINTE* Cell biology, bacterial genomics Department of food sciences and nutrition, FSAA Université Laval Ismaïl FLISS* Microbiology, immunology, probiotics Department of food sciences and nutrition, FSAA Université Laval Sylvie F. GAUTHIER* Food chemistry, enzymology Department of food sciences and nutrition, FSAA Université Laval REGULAR THEME 2 MEMBERS Processes and technologies, quality, stability and protection of bioactive molecules Joseph ARUL** Post-harvest technology, physicochemistry Department of food sciences and nutrition, FSAA Université Laval Dominique MICHAUD** Plant molecular biology, proteomics Plant science department, FSAA Université Laval Yvan CHOUINARD* Animal nutrition, conjugated linoleic acids Department of animal sciences, FSAA Université Laval André GOSSELIN Honorary member Horticulture, greenhouse operations Plant science department, FSAA Université Laval Denis ROY* Coordinator of research theme 1 Microbiology, probiotics Department of food sciences and nutrition, FSAA Université Laval Yves DESJARDINS Plant physiology, in vitro culture Plant science department, FSAA Université Laval Julie JEAN* Virology, food safety Department of food sciences and nutrition, FSAA Université Laval Carole THIVIERGE Animal nutrition, protein metabolism Animal science department, FSAA Université Laval Russell TWEDDELL Mycology, phytopathology Plant science department, FSAA Université Laval Laurent BAZINET* Coordinator of research theme 2 Food engineering, electro-membrane processes Department of food sciences and nutrition, FSAA Université Laval Monique LACROIX Enzymatic hydrolysis, phenolic compounds Immunity, infectious disease and cancer research theme INRS-Institut Armand-Frappier Joseph MAKHLOUF Post-harvest physiology, functional beverages and juices Department of food sciences and nutrition, FSAA Université Laval Khaled BELKACEMI Food engineering, catalytic reactions Department of soils and agri-food engineering, FSAA Université Laval Paul PAQUIN* Honorary member Food technologies Department of food sciences and nutrition, FSAA Université Laval Michel BRITTEN* Fractionation processes, dairy processing Food Research and Development Centre (Saint-Hyacinthe), Agriculture and Agri-Food Canada Yves POULIOT* Food technologies, membrane-based separations Department of food sciences and nutrition, FSAA Université Laval FSAA Faculté des sciences de l’agriculture et de l’alimentation (faculty of agriculture and food sciences) CRDA Centre de recherche et de développement sur les aliments 4 Claude P. CHAMPAGNE Food processing methods, probiotics Food Research and Development Centre (Saint-Hyacinthe), Agriculture and Agri-Food Canada * Regular member of STELA ** Associate member of STELA A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 INAF INAF in 2005-2006 members Members Cristina RATTI Food engineering, food preservation technologies Department of soils and agri-food engineering, FSAA Université Laval Daniel ST-GELAIS* New member Cheese technology, food processing Food Research and Development Centre (Saint-Hyacinthe), Agriculture and Agri-Food Canada Muriel SUBIRADE* Physicochemistry, bio-encapsulation Department of food sciences and nutrition, FSAA Université Laval Sylvie TURGEON* Rheology, milk, polysaccharides Department of food sciences and nutrition, FSAA Université Laval REGULAR THEME 3 MEMBERS Bioassays, nutrition and socio-economic studies Pierre Sélim HADDAD Pharmacology, medicinal plants Department of pharmacology, Faculty of Medicine Université de Montréal Charles COUILLARD Cellular metabolism, lipid oxidation Department of food sciences and nutrition, FSAA Université Laval Sylvie DODIN Gynecology, clinical research Department of gynecology, Faculty of medicine Université Laval Hélène JACQUES** Nutrition, metabolism, diabetes Department of food sciences and nutrition, FSAA Université Laval Peter JONES Nutrition, epidemiology, cardiovascular disease School of dietetics and human nutrition McGill University Benoît LAMARCHE* Nutrition, metabolism, cardiovascular disease Department of food sciences and nutrition, FSAA Université Laval Jean-Christophe VUILLEMARD* Microbiology, lactic cultures Department of food sciences and nutrition, FSAA Université Laval FMED Faculté de médecine FFORG Faculté de foresterie et de géomatique Angelo TREMBLAY Nutrition, energy metabolism, obesity Department of kinesiology, Faculty of Medicine Université Laval Emile Haïm LEVY Nutrition, intestinal malabsorptions Department of gastroenterology, Hôpital Ste-Justine Université de Montréal Yvan BOUTIN Immunology, allergenicity TransBioTech Cégep de Lévis-Lauzon Martin CLOUTIER Strategic management of innovations Department of technology management Université du Québec à Montréal Simone LEMIEUX Nutrition, physiology, diabetes Department of food sciences and nutrition, FSAA Université Laval FPHA Faculté de pharmacie André MARETTE Coordinator of research theme 3 Molecular and cell biology, metabolism, diabetes Department of medicine, Faculty of Medicine Université Laval Marie-Claude VOHL Nutrigenomics Department of food sciences and nutrition, FSAA Université Laval Gale WEST** Agricultural and food economics, sociology Department of food and agricultural economics and consumer science, FSAA Université Laval Charles RAMASSAMY Pharmacology and neurosciences Molecular pharmacochemistry INRS-Institut Armand-Frappier * Regular member of STELA ** Associate member of STELA 5 INAF A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 INAF in 2005-2006 members Members ASSOCIATE MEMBERS Jean AMIOT Food processes and nutrition Department of food sciences and nutrition, FSAA Université Laval Hélène BACHELARD Oxidative stress, endothelial and vascular functions Department of medicine, Faculty of Medicine Université Laval Yacine BOUMGHAR Chemistry, extraction processes CÉPROCQ Cégep de Maisonneuve Marie-Thérèse CHARLES Post-harvest physiology Horticultural research and development centre Agriculture and Agri-Food Canada Patrick COUTURE** Lipid diseases Department of medicine, Faculty of Medicine Université Laval Stephen CUNNANE Nutrition and neurosciences Department of gerontology Université de Sherbrooke Eric DEWAILLY Epidemiology, toxicology Institute of public health, Faculty of Medicine Université Laval Martine DORAIS Plant physiology Soil and Crop Research and Development Centre Agriculture and Agri-Food Canada Steve LABRIE New member Microbial genomics Department of food sciences and nutrition, FSAA Université Laval Marie J. LACHANCE Consumer behaviour Department of agricultural and food economics and consumer sciences, FSAA Université Laval Martin LESSARD Animal nutrition and probiotics Dairy cattle and swine research and development centre Agriculture and Agri-Food Canada Esther MILLETTE New member Pharmacodynamics, antioxidants TransBiotech Cégep de Lévis-Lauzon Claude ROBERT New member Animal nutrigenomics Animal science department, FSAA Université Laval Anne-Laure SAIVES Management of bio-industries Department of technology management Université du Québec à Montréal Anne-Françoise ALLAIN Department of food sciences and nutrition, FSAA Université Laval Monica ARAYA-FARIAS Department of soils and agri-food engineering Université Laval Linda SAUCIER Meat microbiology Animal science department, FSAA Université Laval Geneviève ASSELIN Research centre Hôpital St-François d’Assise Marc-André SIRARD Genomics, reproductive biology Animal science department, FSAA Université Laval Tatjana STEVANOVIC Extraction processes, non timber forest products Department of wood chemistry, Faculty of Forestry and Geomatics Université Laval André TCHERNOF Endocrinology, metabolism Department of food sciences and nutrition, FSAA Université Laval FSAA Faculté des sciences de l’agriculture et de l’alimentation (faculty of agriculture and food sciences) CRDA Centre de recherche et de développement sur les aliments 6 RESEARCH ASSISTANTS Danielle AUBIN INAF clinical studies unit Université Laval Bernard BÉLIVEAU Department of food sciences and nutrition, FSAA Université Laval Claudine BLANCHET Research centre Hôpital St-François d’Assise Amélie CHAREST Department of food sciences and nutrition, FSAA Université Laval * Regular member of STELA ** Associate member of STELA A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 INAF INAF in 2005-2006 members Members Karine COENEN Plant science department Université Laval Louise CORNEAU Department of food sciences and nutrition, FSAA Université Laval Georges COUSINEAU Department of food sciences and nutrition, FSAA Université Laval Hélène GIROUX Food Research and Development Centre Agriculture and Agri-Food Canada Stéphanie JEW School of Dietetics and Human Nutrition McGill University Ehab KHEADR Department of food sciences and nutrition, FSAA Université Laval Nancy GARDNER Food Research and Development Centre Agriculture and Agri-Food Canada Alain GAUDREAU Department of food sciences and nutrition, FSAA Université Laval Nadine LEBLANC Department of food sciences and nutrition, FSAA Université Laval Isabelle MAINVILLE Food Research and Development Centre Agriculture and Agri-Food Canada Isabelle MARC Research centre Hôpital St-François d’Assise Sandra GAGNON Department of food sciences and nutrition, FSAA Université Laval Danielle LAPRISE Research centre Hôpital St-François d’Assise Charles LAVIGNE CHUL research centre Université Laval FMED Faculté de médecine FFORG Faculté de foresterie et de géomatique Céline PAQUIN Department of food sciences and nutrition, FSAA Université Laval Sonia POMERLEAU Department of food sciences and nutrition, FSAA Université Laval Catherine GRAVEL Reproductive biology research centre Université Laval Claire JULIEN INAF clinical studies unit Université Laval Pascal DUBÉ Horticultural research centre Université Laval Yolaine LEBEUF Department of food sciences and nutrition, FSAA Université Laval Johanne MARIN Department of food sciences and nutrition, FSAA Université Laval Julie MAROIS Department of food sciences and nutrition, FSAA Université Laval Alexandre MYRE Animal science department Université Laval FPHA Faculté de pharmacie Yves RAYMOND Food Research and Development Centre Agriculture and Agri-Food Canada Stéphane SALMIERI Immunity, infectious disease and cancer INRS-Institut Armand-Frappier Schohraya SPAHIS Ste-Justine Hospital research centre Université de Montréal Carole THIÉBAUT Research centre Hôpital St-François d’Assise Caroline TRUDEAU Department of food sciences and nutrition, FSAA Université Laval ADMINISTRATIVE PERSONNEL Renée MICHAUD Deputy director Université Laval Sophie BANVILLE Communication Manager Université Laval Louise TREMBLAY Liaison officer Université Laval Marc PARROT Interim liaison officer Université Laval Andrée LAGACÉ Liaison officer Université Laval Raymonde GAGNON Secretary Université Laval Hélène FORTIER Secretary Université Laval Lucille LAROCHELLE Clerk Université Laval Diane VALLERAND Department of pharmacology Université de Montréal * Regular member of STELA ** Associate member of STELA 7 INAF A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 Science enhancing nutrition The INAF scientific program By Yves Pouliot, Scientific director Nutraceutical products, functional foods and human health: meeting the greatest challenges INAF proposes a multi-disciplinary research program of which the principal aim is the discovery of bioactive compounds and the development of ingredients or foods that bring demonstrable benefits in terms of human health. INAF possesses the scientific expertise and technological capacity to identify and improve foods offering the greatest application potential in the nutraceutical products and functional foods sector, to develop manufacturing processes that are viable on an industrial scale, to validate the biological activity of candidate molecules by in vitro tests and by animal and human studies, to verify their safety and to evaluate the acceptability of these novel products to consumers. The components of the scientific program INAF carries out its activities in accordance with the objectives of a scientific program divided into three main themes of research and two special interest groups. THEME 1 THEME 2 THEME 3 Identification, characterization and functionality of bioactive molecules Processes and technologies, quality, stability and bio-protection of bioactive molecules Nutrition, pre-clinical, clinical and socio-economic studies Coordinator: Denis Roy Coordinator: Laurent Bazinet Coordinator: André Marette 1 Lactic acid bacteria 1 Technological strategies 1 Pre-clinical: bioassays and probiotics 2 Biologically active proteins/peptides 3 Phytoantioxidants 4 Lipid compounds to manufacture fractions enriched in bioactive molecules 2 Safety, quality and stability 3 Bio-protection 1 23 and cytotoxicity 2 Clinical nutritional studies 3 Nutrigenomics 4 Functional proteomics 5 Attitudes and perceptions of consumers Health targets INAF research activities are focussed on health targets that constitute major challenges for industrialized countries and that have a direct link to nutrition. The aim of our work is thus to apply the science of nutrition to the prevention of major chronic diseases such as obesity, diabetes, cardiovascular disease, gastrointestinal disorders, immune disorders and illnesses related to aging. 8 In addition, the scientific program encompasses the scientific and transfer-related activities of two additional subsets of researchers whose work focuses on topics of major economic significance due to the importance these industry sectors in Quebec: the Plant products group (fruits and vegetables, indigenous plants) and the Dairy products group, consisting essentially of the STELA centre. These groups play a major role in integrated and sector-targeted research within INAF. A summary of their activities is provided at the end of the present section. A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 INAF Science enhancing nutrition Productivity at a glance The scientific productivity of INAF for 2005-2006 reflects the objectives undertaken by the organization. First of all, INAF researchers individually carried out over 65 fundamental research projects. This work is of major significance since it is the very source of new discoveries and of understanding of the mechanisms of action of bio-molecules. The main Canadian granting agencies participating in the funding of this work are the Canada Research Chairs Secretariat, the Natural Sciences and Engineering Research Council (NSERC) and the Canadian Institutes for Health Research (CIHR). At the provincial level, the Jeunes Chercheurs program of the Fonds québécois de recherche sur la nature et les technologies (FQRNT) has allowed the recruitment of no less than six new researchers since the creation of INAF in 1999. Multi-disciplinary teams allows the resolution of complex problems often occurring at the interface between two or more scientific disciplines. The Institute contributes actively to integrated research, from characterization and protection of active ingredients to clinical nutritional studies for the purpose of demonstrating their effects on the health of the population. In 2005-2006, 19 new projects were added to those already underway, bringing the number of such projects to 96. The following section lists projects that best illustrate the multi-disciplinary aspect of research at INAF. These were made possible thanks to the health and natural science research granting agencies in Quebec and Canada, as well as the participation of numerous private partners. The participation of industry in this type of work makes it possible to carry out projects that truly take into account the socio- and technoeconomic issues associated with the sector and favour the transfer of technology and know-how. It should also be emphasized that INAF researchers have contributed to more than 35 projects of a competitive nature paid for entirely by industry. The list of private sector partners, who numbered more than 95 in 2005-2006, is provided at the end of the present report. The following figure illustrates the distribution of the INAF budget by type of grant. These data include grants totalling $2 million obtained by the researchers for improvement of infrastructures and equipments as well as the $1 million annual operation budget. The sums invested directly in research thus reached $11.5 million during this period. In order to provide a realistic view of the research budget, the mega network grants in which INAF researchers have a minor participation, in kind contributions from partners and salary supplements have not been included in these charts. INAF funding in 2005-2006, by type of grant $2 M INAF researchers have been particularly productive with respect to the dissemination of their research results, as may be appreciated by examining the titles of the scientific publications and communications listed in appendix. These include 198 publications in peer-reviewed scientific journals • More than 60 of these involving at least two INAF researchers • More than 90 having an INAF graduate student as first author 310 communications $2 M $6.6 M $1 M • 189 of national reach • 121 with international reach Six patents granted Four patent applications pending $2.6 M Equipment Operations Individual grants Team grants Contracts 9 INAF A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 Science enhancing nutrition The INAF research themes 1 23 THEME 1 Identification, characterization and functionality of bioactive molecules THEME 2 Processes and technologies, quality and stability of bioactive molecules THEME 3 Bioassays, nutrition and socio-economic studies Scope of the problem: Scope of the problem: Scope of the problem: Numerous foods offer major opportunities in the nutraceutical products or functional foods sector because of their bioactive molecule content. Due to their economic significance and application potential, the following components are receiving special attention at INAF: lactic and probiotic bacteria, proteins and peptides with biological activity, antioxidants from plants and lipid compounds. The work defined by theme 2 addresses the scientific challenges imposed by the development of high-performance manufacturing processes for obtaining products of exemplary quality and stability. There is a need in this sector for improved technological strategies for the extraction of bioactive components and for protection of bioactive molecules. The development of food ingredients and products having beneficial effects on health and disease prevention must include rigorous demonstration of their safety and efficacy. Scientific aims: Scientific aims: 1 To increase the utilization of natural resources of Quebec by identifying bioactive molecules in milk, dairy products, fresh produce (fruits, vegetables, herbs) and marginally used species (indigenous Quebec mushrooms, algae, herbaceous plants); 2 To improve microbial (lactic and probiotic bacteria) as well as plant and animal species of Quebec in order to optimize their bioactive molecule contents; 3 To utilize the sciences of genomics and proteomics to characterize the biochemistry and function of these microorganisms and bioactive molecules; 4 To elucidate the mechanisms of action of these organisms or bio-molecules. 10 1 To develop new technological strategies, economically viable on an industrial scale, for producing, isolating and concentrating bioactive molecules; 2 To evaluate the impact of technological processes on the physicochemical and functional quality and stability of bioactive molecules; 3 To develop protective biomatrices capable of stabilizing fragile molecules. Scientific aims: 1 To study the positive impact as well as the potentially deleterious effects of nutraceutical molecules on health by means of pre-clinical studies; 2 To validate the impact of biologically active molecules on certain physiological functions involved in the etiology of problems such as cardiovascular disease, obesity, gastro-intestinal disorders, menopause and type-2 diabetes; 3 To study the relationships between genes and diet in the prevention of chronic diseases; 4 To characterize the impact of nutrients on the serum proteome and identify metabolic biomarkers associated with certain food-related disorders; 5 To study the socio-economic aspects of the consumption of nutraceutical products and functional foods. A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 INAF Science enhancing nutrition The INAF research themes Examples of multidisciplinary and inter-theme team projects in progress in 2005-2006 Project title Researchers THEMES 1 2 3 Exploration of the meta-genome of the microflora associated with maple sap collection systems and determination of its impact on the quality of maple products Roy, D., LaPointe, G. • • Characterisation, utilization and processing of seabuckthorn in Québec Ratti, C., Belkacemi, K., Makhlouf, J. • • Growth factors from cow milk: extraction, characterization and biological activity Gauthier, S. F., Pouliot, Y., Turgeon, S., Poubelle, P. • • Genomic analysis of the industrial performance of lactic ferments in cheesemaking LaPointe, G., Roy, D. • • The efficacy of bacteriocins against fungal pathologies Rouabhia, M., Fliss, I., Subirade, M. • Polysaccharides and bioactive derivatives from Laminaria longicruris Turgeon, S., Roy, D. • • NSERC dairy industry research chair on cheese technology and type characterization Roy, D., Labrie, S., Turgeon, S., St-Gelais, D. • • Bacteriocin-producing bifidobacteria and equilibrium of the intestinal microflora Fliss, I., Boutin, Y., LaPointe, G., Subirade, M. • Identification of immuno-modulating components in whey-protein-based products Gauthier, S. F., Boutin, Y., Fliss, I. • • Biological activity of minor components of buttermilk and whey Pouliot, Y., Gauthier, S. F., Jean, J. • • • Enrichment of fruit juices with encapsulated compounds Makhlouf, J., Turgeon, S., Vuillemard, J.-C. • • Nutraceutical ingredients of dairy fat enriched with conjugated linoleic acid and vaccenic acid: production, use and beneficial effects against neurodegenerative diseases Arul, J., Angers, P., Belkacemi, K., Chouinard, Y., Haddad, P., Ramassamy, C. • • • Electrochemical regulation of the redox potential of milk: impact on processing efficiency and product quality Britten, M., Angers, P., Bazinet, L., Champagne, C.P., Pouliot, Y., Vuillemard, J.-C. • • Development of bacteriocin- and chitosan-based bio-films for inactivating pathogenic and marine product spoilage microflora Fliss, I., Boutin, Y., Subirade, M. • • Development of nano- and micro-particulate vehicles for preserving the functions of nutraceutical molecules and optimizing their bioavailability: application to natural antioxidants Subirade, M., Angers, P., Ramassamy, C. Development of an integrated approach to increase the utilization of buttermilk solids Pouliot, Y., Angers, P., Bazinet, L., Britten, M., Gauthier, S. F., Michaud, D. • • Thermal and oxidative stability of dairy fat fractions enriched in CLA and their stabilization for preventing oxidative deterioration Angers, P., Arul, J., Belkacemi, K. • • Prebiotic potential of conjugated linoleic acids of dairy origin: in vitro analysis and effects on the gastro-intestinal ecosystem Fliss, I., Champagne, C.P., Chouinard, Y., Farnworth, E. • • • Development of foods containing xylitol for a project aimed at reducing the incidence of dental cavities in high-risk Quebec children Giasson, L., Lemieux, S., Turgeon, S. • • Evaluation of the insulin sensitivity of insulin resistant individuals fed fish protein Jacques, H., Marette, A. • • Study of the impact of trans fat of dairy origin on the blood lipid profile Lamarche, B., Chouinard, Y., Couture, P., Lemieux, S., Paquin, P. • • • • • • • • 11 INAF A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 Science enhancing nutrition Research Chairs Canada research chairs Denis Roy is the holder of the Canada Research Chair in Lactic Culture Biotechnology for Dairy and Probiotic Industries (level 1), which aims at increasing the understanding of lactic cultures and probiotics, particularly of exopolysaccharides, used for processing functional foods and to enable scientific validation of the effects attributed to probiotics for medical and nutritional purposes. Muriel Subirade holds the Canada Research Chair in Protein, Biosystem and Functional Food Physical Chemistry (level 2). Ms. Subirade seeks to exploit the properties of proteins in order to protect and transport the bioactive molecules forming the nutraceutical basis of foods towards precise biological targets. The Canada Research Chair in Physical Activity, Nutrition and Energy Balance (level 1) was awarded to Angelo Tremblay, a specialist in energy balance and its role in the prevention of obesity. The chair work is devoted to the associations between physical activity and diet as well as to understanding the phenomena that lead to obesity in order to develop rational programs of prevention. Benoît Lamarche holds the Canada Research Chair in Nutrition, Functional Foods and Cardiovascular Health (level 2). The aim of his work is to study the impact of dietary habits, particularly the 12 use of functional foods and nutraceutical products, on cardiovascular health, blood lipoprotein metabolism and cardiovascular disease risk factors in order to identify new avenues of disease prevention and therapy. In Sherbrooke, a Canada research chair under the direction of Stephen Cunnane focuses at the impact of dietary fatty acids on cognition throughout aging. The aim of this chair is to understand the association between fatty acid utilization by the organism and the maintenance or loss of cognitive functions with age, in order to pave the way for new dietary recommendations and drugs. Other research chairs Chair in human nutrition, lipidology and cardiovascular disease prevention The Lucie and André Chagnon chair for the advancement of integrated approaches to disease prevention This chair was created at the Faculty of medicine of Université Laval in 2001 with the aim of promoting and providing financial support to university research and teaching in holistic health and disease prevention. The chair also promotes rigorous scientific evaluation of complementary and alternative care approaches and their integration into health care practices. The holder of this endowed chair, Dr. Sylvie Dodin, is a regular INAF member. Several chair activities, such as training and knowledge transfer, are in line with the mission of INAF. The seminar presented by France Légaré at INAF in April 2006 was a joint invitation of INAF and this chair. This endowed chair, held by Benoît Lamarche, is connected to the Faculty of agriculture and food science at Université Laval. Its goal is to promote and support university research and teaching in this multidisciplinary field. Over the course of the year, the chair has provided: • organization of a free conference for the general public as a side feature to the International Symposium on the Health Effects of Fruits and Vegetables (presented in the Events section of this report); • contribution to the salary of a Quebec Fonds de recherche en santé -Young researcher grant recipient, Dr. Charles Couillard, whose expertise and work deal with the antioxidant and antiinflammatory potential of nutraceutical products and functional foods in the context of cardiovascular disease prevention. NSERC Industrial Research Chair on cheese technology and type characterization The holder of this new NSERC dairy industry research chair is Denis Roy, whose expertise in lactic acid bacteria and probiotic bacteria is widely recognized. His team will use molecular genetics to decipher the role and fate of micro-organisms in mozzarella, cheddar, camembert and Swiss cheeses. The chair industrial partners are Novalait, Dairy Producers of Canada, Saputo, Agropur Coopérative, Parmalat and Damafro. Steve Labrie has joined the INAF membership as an associate member and collaborating researcher with this chair. A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 INAF Training of highly qualified personnel Studying at INAF, taking the path to success In any given year, more than sixty INAF researchers working in various disciplines and organizations provide training, guidance and otherwise support numerous student researchers from all around the world, with the assistance of a solid team of specialists highly qualified in fundamental, applied and clinical research, as well as of highly capable administrative personnel. One of the most significant achievements of the year 2005-2006 is without any doubt the training of the largest cohort of student researchers since the creation of INAF in 1999. In fact, nearly 300 young scientists have been trained at INAF, of which 66 are currently new recruits and 55 have graduated. The number of post-doctoral researchers has increased during the year from 28 to 33. It should be noted that INAF research teams also welcome year after year about 50 undergraduate interns, of which several subsequently return to do masters program studies. Ever mindful of improving the study environment and better serving its student clientele, INAF implemented in 2005-2006 the latest version of its integration policy. Developed for the purpose of facilitating the arrival and integration of new students, this policy also provides them with access to various support mechanisms such as post-doctoral fellowship salary supplements and financial support for presentations at international scientific meetings. Post-doctoral researchers Seminar Day 21% 24% France Because of its multidisciplinary nature and innovative research program, INAF constitutes an environment of choice for carrying out post-doctoral research projects. In addition to polishing their research skills and increasing their knowledge in forefront subject areas, post-doctoral researchers have numerous opportunities to acquire experience in supervision and management, since they very often take up major roles in the coordination of the research teams in which they evolve. Left to right: Benoît Lamarche, director of INAF, post-doctoral researchers Véronique Delcenserie, Stéphanie-Marie Deutsch, Luigi Bouchard and Alicia Montoni and INAF scientific director Yves Pouliot. Statistics on the training of student researchers Total New students In training Graduates The following figure illustrates the origins of INAF post-doctoral researchers. Although French speaking countries are dominant for obvious reasons, Africa, Asia and South America nevertheless represent more than a third of the post-doctoral researchers trained at INAF. Masters Doctoral Post-doctoral Total 150 44 72 34 111 12 90 9 33 10 14 9 294 66 176 52 Québec 15% 40% North Africa and Central Africa Asia and South America In order to allow all INAF members to get to know better some of these up and coming young researchers and to discover the diversity of their works, conferences were organized and held on January 12, 2006. These provided the opportunity to see the following presentations: • Functional genomics for better understanding of complex traits: Applications to the metabolic syndrome Luigi Bouchard, Ph.D., team of Marie-Claude Vohl • Bacterial lysis in cheese Stéphanie-Marie Deutsch, Ph.D., team of Denis Roy • Development of molecular tools of detection of bifidobacteria in foods and evaluation of these organisms as indicators of fecal contamination Véronique Delcenserie, Ph.D., team of Denis Roy • Characterization of new receptors of VIP family neuropeptides and other works Alicia Montoni, Ph.D., team of Sylvie Gauthier 13 INAF A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 Science enhancing nutrition STELA Centre [dairy research] Summary of activities for 2005-2006 By Sylvie Turgeon, director The integration of the STELA centre into the administrative structure of INAF in 2004-2005 contributed strongly to consolidating the membership of both units. In fact, although all of these researchers were already working in close collaboration, not all STELA regular members were associated with INAF. Conversely, several INAF members conducting projects relating to the health effects of milk were not considered members of STELA. We therefore undertook in 2005-2006 the major exercise of revising membership and status, which brought about the integration of new The NSERC-CRD research project on the growth factors of milk reached its cruising speed in 2005-2006. Shown here is Ms. Sylvie Gauthier in the company of her team of Université Laval and Advitech researchers. The project involves two post-docs, four doctoral students and two masters students as well as two undergraduates hired for the summer of 2005. Research funds for this project total over $1.2 million over three years. regular and associate members into both INAF and STELA. We make a special note here that our dairy sector collaborators at Agriculture and Agri-Food Canada, Michel Britten and Daniel St-Gelais, have now joined STELA as regular members. The Centre has also maintained its outreach effort in research and training as well as its collaborations with dairy sector partners. STELA research activities remain as intense as ever, with a budget of $3.1 million in 2005-2006, 57% of this coming from industry. Moreover, the industrial involvement in the transfer of knowledge and technologies developed by academic research is a great source of pride for STELA. The research has led to the publication of 42 scientific articles, 11 conference abstracts and 102 other communications. 14 STELA research activities remain as intense as ever, with a budget of $3.1 million in 2005-2006 The number of students has reached 33 masters and 32 doctoral, in addition to 10 post-doctoral researchers and 15 foreign interns or undergraduate students. The number of graduates for this year is eight masters and six doctoral. One of the major accomplishments for the year is without any doubt having brought six dairy industry partners to contribute to the funding of an industrial research chair on cheese technology and type characterization. In fact, the companies Agropur, Saputo, Parmalat and Damafro as well as Dairy Producers of Canada and Novalait are providing a total contribution of one million dollars over five years for research on the genomics of cheese microbiota and management of mineralization. A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 INAF Science enhancing nutrition STELA Centre • To implement metagenomics as an avantgarde field of research that will help to develop new tools to gain better control over metabiosis or the succession of microorganisms during cheese ripening; In terms of staffing, STELA has welcomed a new liaison officer, Ms. Andrée Lagacé, to replace Ms. Louise Tremblay, who has taken a position at the Faculty of agriculture and food science of Université Laval. • To broaden and deepen knowledge of the expression of microbial metabolism during each of the stages of ripening; We thank Ms. Tremblay for her devotion and wish her success in her new functions. Ms. Lagacé is responsible for coordinating relations with industrial partners, assisting the direction with the set-up and followthrough of major projects and participating in the publication of INFO-INAF and Fax-Lait, among others. NSERC has matched this investment and Université Laval is adding $125,000 for a grand total of $2.125 million. The creation of this industrial research chair, held by Dr. Denis Roy, is a shining example of collaboration between a granting agency and an industry mobilizing around universitygrown know-how. It is the result of a strategic alliance between Université Laval and one of the largest businesses in this field in the country. • Consolidate a pole of skills and knowledge; The goals of the NSERC Industrial Research Chair on cheese technology and type characterization are: • To train highly qualified future professionals that will carry the torch in the industry and in research labs. • To develop a novel approach to better understand the impact of processes and manufacturing parameters on the composition, structure, physicochemical interactions and functional properties of cheese; World Dairy Summit STELA was closely involved in the organization of the milk science and technology session of the World Dairy Summit of the International Dairy Federation (IDF), which took place in Vancouver in the fall of 2005. This summit attracted over 800 participants from all over the world. The presentations covered well-targeted themes in the fields of nutrition and dairy policy, economics and technology. Mr. Paul Paquin, assisted by Louise Tremblay, presided over the scientific committee responsible for the call for papers and review process. The science and technology session included 16 presentations by scientists from The Netherlands, Germany, France, Finland, Japan, the United States and Canada. Mr. Paul Paquin, honorary member of STELA and INAF, acted as president of the scientific committee of the World Dairy Summit of the International Dairy Federation (IDF), which took place in Vancouver in the fall of 2005. 15 INAF A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 Science enhancing nutrition Plant products research group Summary of activities for 2005-2006 By Yves Desjardins, coordinator The plant products research group is a multidisciplinary team of researchers from all three themes of INAF research. Its aim is to create synergy between the disciplines and to advance knowledge in the area of the functionality of bioactive molecules of plant origin. The year 2005-2006 provided the kick-start to the knowledge transfer activities of this group. In fact, INAF organized the first international symposium on the health effects of fruits and vegetables (FAV Health 2005), as well as the very first Seminar on the health effects of cranberries. Held simultaneously at the Hotel Loews Le Concorde in August of 2005, these two international events of exceptional quality provided a showcase for several INAF researchers and their collaborators. FAV Health 2005 International symposium on the health effects of fruits and vegetables August 17-20, 2005 Plant products, particularly fruits and vegetables, are an exceptional source of bioactive molecules with health effects. Numerous studies show that regular consumption of these foods reduces the incidence of diseases such as cancer, cardiovascular disease, diabetes and several others. Although epidemiological studies provide compelling evidences of the positive impact of fruits and vegetables on health, the mechanisms of action of the bioactive molecules they contain remain unknown in many cases. For actors in the production and processing sectors, cultivation methods, post-harvest handling as well as the storage and distribution chain are all factors that may affect the bioactive compound contents of fruits and vegetables. Organized by INAF and overseen by the International Society for Horticultural 16 FAV Health 2005 attracted 150 participants from 28 countries. Science, FAV Health 2005 highlighted the most recent scientific evidence on these subjects and provided researchers in the agri-food sciences and medical sciences with a privileged forum on the positive impact of fruit and vegetable consumption on health. I, along with my colleague Bihmu Patil at the University of Texas A&M, co-chaired this event, which took place at the Quebec Hotel Loews Le Karine Pedneault of INAF, doctoral student under the supervision of Russell Tweddell, Paul Angers and André Gosselin, recipient of first prize Concorde on August 17- for the best student presentation. She is accompanied here by Joe Mazza 20, 2005 and attracted of the Pacific Agri-Food Research Centre at Summerland (British Columbia) 150 participants from 28 and by Yves Desjardins, academic director of INAF. countries. The first event of this kind to assemble several others among its prestigious guests. at the same time experts from the horticulThe organizers benefited from the expertise tural and health sectors, FAV Health 2005 of Ms. Sophie Banville, communication counted representatives of the United manager at INAF, for the organization of Nations Food and Agriculture Organization this event. (FAO), the World Health Organization (WHO), Université de la Méditerranée and A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 INAF Science enhancing nutrition Plant products research group A smashing success overall, FAV Health and its peripheral activities drew a lot of media attention. This activity was made possible by major support from Agriculture and AgriFood Canada, the Quebec Ministry of Agriculture, Fisheries and Food (MAPAQ), Fondation Lucie et André Chagnon, the Quebec Association of Cranberry Growers and several other partners. Seminar on the health effects of cranberries August 18-19, 2005 Taking advantage of the spectacular rise in the popularity of cranberries and their health effects in the population, the Quebec Association of Cranberry Growers joined forces with INAF to organize the very first Seminar on the health effects of cranberries with the assistance of the INAF communication manager, Ms. Sophie Banville. The Seminar was designed to appeal mainly to stakeholders involved in the production and processing, in order to present the most recent results of clinical studies on cranberries and their derivatives This event was designed to reach mainly a grower and processor clientele, for the purpose of presenting the most recent results of clinical studies on cranberries and their derivatives. Sponsored by the Royal Bank of Canada, Ocean Spray and several other financial partners, the event gathered more than 200 participants from five countries, five Canadian provinces and seven American states. Genetic selection and cultivation methods were presented along side bacterial anti-adhesion properties of proanthocyanidins and the competitiveness of North American producers in the world cranberry market. The program included a day set aside for visits to cranberries farms in the Lotbinière region. Held also at the Hotel Loews Le Concorde, the Seminar was offered with simultaneous translation, allowing all participants to hear the seven excellent speakers, who had prepared presentations well adapted to the interests of their audience. In addition to giving scientific presentations at FAV Health 2005, several research experts such as Charles Couillard of INAF and Amy Howell of Rutgers University in New Jersey adapted their talks to the non-scientific audience of the Seminar on the health effects of cranberries. The Seminar on the health effects of cranberries was presided by Madame Marie Bieler, director of Canneberges Atoka Inc. and treasurer of the Quebec Association of Cranberry Growers. Finally, three seminars were presented within the themes covered by the plant products research group. These presentations, by Dr. Thomas Wolever, Dr. Susan J. Murch and Dr. Grant Pierce, are described in the Conferences and Seminars section of this report. Beautiful weather showed up for the second day of the Seminar, during which participants had the opportunity to visit three major cranberry-producing businesses in the Lotbinière region. 17 INAF A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 Strategic development By Renée Michaud, Deputy director In 2005-2006, INAF initiated new actions and new strategic partnerships in order to maximize the benefits from its work in terms of development and transfer of knowledge and technology. INAF plan of action for 2006-2011 The preparation of the plan of action 2006-2011 entitled “Becoming an international reference” was guided by a diagnosis of the internal and external environment in which INAF is evolving, taking into consideration key factors of success and issues unique to research organizations. This five-year plan, the fruit of a lengthy process of review, analysis and consultation, was presented to INAF members during the 20052006 annual meeting. The six major strategic orientations spelled out in this document are: • To enrich the scientific research program in order to respond to new economic, educational and social issues; • To become a first choice for the training of highly qualified personnel in Quebec and Canada; • To offer INAF students and researchers a privileged working environment; • To become a highly seeked partner for industry in terms of expertise, innovation and technology transfer; • To affirm the role of INAF as a reference in the realm of food processing, nutrition and health for ministries, health professionals and the general public; • To affirm the role of INAF as a leader on the Canadian scene and reinforce its international positioning. For each of these major orientations, the plan proposes specific objectives to be achieved, actions and means to achieve them as well as follow-up measures and indicators. An excellent management tool, this plan of action is an indispensable reference to enable INAF direction to lead the organization to new heights. 18 To favour innovation and technology transfer Knowledge and technology transfer is an integral part of INAF’s mission. Like many organizations, we have learned that the technology transfer process requires persistent effort and coordination. In order to support our researchers better in this endeavour and to allow INAF to be a proactive player in the chain of innovation in the nutraceutical products and functional foods sector, a pilot project was set up in 2005-2006. This project was made possible by financial support from Economic Development Canada (EDC) and the Quebec Ministry of Economic development, Innovation and Exportation (MDEIE), with the participation of the vice-rectorate for research at Université Laval and SOVAR. Among the major findings of this exercise, we must first note the great capacity for innovation within INAF. The study enabled us to list at least 40 innovations that led to invention disclosures or patents since the starting up of INAF. Technical data sheets were produced for the presentation of innovations offering the greatest potential for commercial utilization, in order to improve the process of informing potential users. The study also allowed us to identify measures to implement in order to provide increased support to researchers during the invention disclosure process, proof of concept and so on. It also became apparent that INAF must get involved and devote the necessary resources to mobilizing and grouping the primary actors of research, development, transfer, financing and industry around a concerted model of which the primary goal is to maximize the benefits from the research and thereby promote the rise of the nutraceutical products and functional foods industry. The Boards of directors is thus continuing the necessary efforts in this sense. Patent applications published Bazinet, L., Labbé, D., Tremblay, A. 2005. Method for selectively and sequentially extracting catechins from plant product. (US 2005/0176939). Fliss, I., Desbiens, M., Lacroix, C., Tahiri, I., Benech, R., Kheadr, E.E. 2005. Bacteria strain and bacteriocin produced therefrom. (CA2,507,566; US2005/0245443). Fliss, I., Lacroix, C., Le Blay, G., Cinquin, C.F., 2005. In vitro gastrointestinal model system and uses thereof. (CA2,386,554; US 2005/0186633). Beaulieu, L., Subirade, M., Groleau, D., Legault, 2006. Lactic acid bacteria-derived bacteriocin and uses thereof for prevention or treatment of cancer. (WO/2006/053445). Bazinet, L., Ling Teng Shee, F., Angers, P., Ben Ounis, W. Method for extracting lipids from biological solutions. (WO2005/099876). Bazinet, L., Amiot, J.; Poulin, J.-F; Tremblay, A., Labbé, D. Process and system for separation of organic charged compounds. (WO2005/082495). Patent applications filed Berthiaume, D., Labrecque, J. et Angers, P. Dielectric coolants for use in electrical equipment. Application, January 13, 2006. (PCT/CA2006/000045). Laneuville S.I.B., Turgeon, S.L., Paquin, P., Sanchez, C. Gelation of undenatured proteins with polysaccharides. August 4, 2005. (PCT/CA2005/001216). Laprise, M. et Chouinard, P.Y., 3 juin 2005. Method and composition for increasing omega-3 lipid in milk. Propriété conjointe Centre de recherche et de développement en agriculture et Université Laval. (CA2,509,125 ; US11/144,007). Angers, P., Boutin, Y., Gosselin, A., Tweddell, R., Pacheco-Sanchez M. Glucan and uses thereof. (US60/733,760). Invention disclosures Lacroix C., Grattepanche F. Method of enhancing acid production in low acid producing bacteria. (US60/811,367). A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 INAF Strategic development Supporting the rise of the industry by the creation of a new association In response to an increasing demand from industrial partners of INAF and STELA, the Institute played a key role in creating and setting up the Association for Health Ingredients in Foods (AHIF), which began its existence 2005. At the intersection of research, health and industry, the AHIF has undertaken the mission of generating and providing to society credible information on nutritional health effects and health claims by compiling a source of information validated by experts, and, of informing and aiding its members in their decision making. It was thanks to the involvement of Denis Roy, who is still playing an active role as a scientific advisor to the AHIF, that INAF rallied the interests of the sector around this project, which quickly benefited from start-up funds provided by the Ministry of Agriculture, Fisheries and Food (MAPAQ). For more information, visit the AHIF website. www.aisa-ahif.org Promotion of regional products Fruit and vegetable growers in the Quebec City region have entered into an association with experts in the Ministry of Agriculture, Fisheries and Food (MAPAQ) Quebec City regional administration, the Fierbourg career training centre and INAF for the purpose of supporting the implantation and promotion of new or unusual fruits and vegetables. Within this partnership, the nutritional and nutraceutical value of the product is analyzed and described and the product is then presented within gastronomical recipes developed at Fierbourg. The end result takes the form of magnificent recipe sheets, which producers supply to the various selling and distribution points of their products. Terroir & Savoir is the quality label associated with this new way of increasing the utilization of regional products. At INAF, this project was assigned to a team made up of Pascal Dubé, chemist, Louise Corneau, nutritionist and Sophie Banville, communication manager. Launching of the Nutrition & Health Clinic It was this year that the new Nutrition & Health Clinic was able to offer its first consulting services in specialized nutrition, cardiovascular health and nutritional behaviour. Open to the university community as well as the general public, the clinic offers individual consultations focused on the pleasure of eating, an approach that favours the acquisition and long term maintenance of healthy eating habits. Supervised by Benoît Lamarche, the clinic also organizes conferences and activities in the areas of nutrition, cardiovascular health and the psychosocial aspects of diet for continuing education programs and for increasing awareness in the public. Involvement in Canada-wide initiatives Throughout the year, the directors devoted much of their energy to consolidating the position of INAF on the Canadian scene. INAF participation in the following must be mentioned: • Advanced Foods and Materials Network (AFMnet) research activities (NSERC/ SSHRC/CIHR network of centres of excellence); • Activities of a Canadian task force on research potential in nutrigenomics, to be submitted to Genome Quebec and Genome Canada. • The structuring of the Canada-wide project NutriNet Canada, of which the aim is to favour the growth of the Canadian nutraceutical products and functional foods industry by developing a strategic plan, coordinating regional and Canada-wide activities that combine the talents in the sector and by initiating projects aimed at responding to the pressing needs of the industry in terms of regulation and marketing. This project was submitted to Agriculture and Agri-Food Canada within the Agriculture Policy Framework Science and Innovation Brokering Program. 19 INAF A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 Events A bounty year for knowledge transfer The year 2005-2006 was particularly fertile in events intended for a wide variety of clienteles. In fact, in addition to the events described in the preceding sections of this report, INAF held seven other events and presented 11 seminars within the framework of its program of scientific presentations. All activities considered, INAF and its members coordinated and organized more than 140 lectures or posters, which were seen or heard by over 1,800 people. Although it is difficult to evaluate exactly how many people the guest speakers and communications by researchers and students reached within the context of other events (in appendix), it is clear that the outreach of INAF is exceptional. Left to right: Gilbert Drouin (VRQ), Benoît Lamarche (INAF), Sylvie Dillard (FQRNT), Jean-Paul Laforest (FSAA), Yves Pouliot (INAF), Paul Paquin (FSAA), Jean-Maurice Plourde (CQVB), Renée Michaud (INAF), Jean Amiot (ALN). tions and companies, and some are even designed specially with their interests in mind (Nutra-Innovation Network). With the free public ‘À Votre Santé!’ Seminar and the noted participation of INAF at the ‘Semaine de l’Agriculture, des Pêcheries et de l’Alimentation’, the year 2005-2006 marked the beginning of increased visibility to the general public. The majority of events obviously target the scientific community, since it is from the sharing of research results and exchanges among researchers that network-building projects and initiatives arise. Nevertheless, several of these events are also open to partner organiza- 20 The communication and knowledge transfer activities implemented by INAF reach an increasingly vast clientele from year to year INAF Members Annual Meeting June 23, 2005, Château Bonne Entente, Québec The 160 INAF members who attended this meeting had the privilege of hearing Mrs. Sylvie Dillard, president and director of the Fonds québécois de recherche sur la nature et les technologies, Mr. Gilbert Drouin, president and director of Valorisation Recherche Québec and Mr. Jean-Maurice Plourde, president and director of the Centre québécois de valorisation des biotechnologies. These heads of granting agencies expressed their pride at being associated with the success of INAF, which they readily cite as a shining example in several forums and encouraged its members to spare no effort in maintaining the dynamic character and the quality of this unique grouping of talent. A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 INAF Events A bounty year for knowledge transfer À VOTRE SANTÉ! Conference on fruit and vegetable consumption and health open to the general public Semaine de l’Agriculture, de l’Alimentation et de la Consommation (SAAC) August 17, 2005, Hotel Loews Le Concorde, Québec On average, over 15,000 people visit the numerous stands at this yearly exhibition organized by undergraduate students from the Faculty of agriculture and food science and in which INAF participates every two years. With the aid of colour posters and explanatory pamphlets, graduate students provided presentations aimed at the general public describing research projects in progress at INAF. The conference “À votre santé!” for the general public and devoted to the association between fruit and vegetable consumption and health, kicked off the fruits and vegetables trio held in the month of August 2005. The 400 participants literally feasted the three presentations by nutritionists Simone Lemieux, INAF researcher, and Hélène Laurendeau, well-known television commentator, as well as best-selling author Dr Richard Béliveau of Sainte-Justine Hospital. Science of course, but also culinary hints and humour were on the menu at this evening event, which was a smashing success. Organized by INAF’s Chair in human nutrition, lipidology and cardiovascular disease prevention, the activity was sponsored in partnership with Provigo and Pfizer Canada. January 20-22, 2006, Centre de foires, Expo-Cité, Québec The Quebec Minister of Agriculture, Fisheries and Food, Mr. Yvon Vallières and the communication manager at INAF, Ms.Sophie Banville (on the right), listen attentively as Julie Paquin (left) and Laurie-Eve Rioux (centre) explain the technological challenges associated with enriching certain foods with dietary fibre. Canada’s Functional Food R&D Dream team May 28 to 30, 2006, Hotel Delta Centre Ville, Montréal INAF contributed actively to the organizing committee of the joint Canada-wide congress of the Canadian Institute of Food Sciences and Agriculture and AgriFood Canada. Dr. Jean Amiot, director of the department of food sciences and nutrition at Université Laval, organized and presided a half-day mini-symposium entitled: Functional Foods and Nutraceuticals: Canada’s R&D Dream Team. This thematic activity allowed participants to discover Canada’s extraordinary research capabilities in the area of functional foods and nutraceuticals including presentations by the directors of the four biggest Canadian research centres in the sector: the Richardson Centre for Functional Foods and Nutraceuticals in Manitoba (P. Jones); the Advanced Food and Materials Network in Ontario (R. Yada); the Institute of nutraceuticals and functional foods in Quebec (B. Lamarche) and the NRC Institute for Nutrisciences and Health in Prince Edward Island (M. Mayne). More than 400 people appeared at the Hotel Loews Le Concorde on this magnificent August evening to listen to three presentations on the importance, the benefits and the pleasure of eating more fruits and vegetables. 21 INAF A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 Events Nutra-Innovation Network Functional foods and nutraceutical products – Status and knowledge Second INAF symposium, October 6-7, 2005, Hotel Plaza, Québec The Nutra-Innovation Network intends to bridge the gap between scientists and industry, in addition to increasing knowledge transfer and allowing INAF researchers to keep abreast of industry needs. This liaison activities program was set up by INAF in collaboration with the Centre québécois de valorisation des biotechnologies (CQVB). Technological meetings devoted to targeted themes, as well as the production of information sheets on emerging technologies or industrial and market trends are carried out for the benefit of Quebec industries in the sector. Since its creation, this program has given rise to numerous alliances with the industrial community. Drs Joël Pincemail (Université de Liège, Belgique), Raymond Christon (INRA Jouy-en-Josas, France), Ian Newton (Ceres Consulting, Ontario) and Gerhard Rechkemmer (Technical University of Munich, Germany) were among the special guest of the Symposium. 22 The symposium’s avant-garde program included 13 presentations by INAF members, four by international guest speakers, (Germany, Belgium, Finland, France), four by industry representatives and over 70 posters. The symposium showcased not only the most recent work under each of the major research themes of INAF, but also work done elsewhere as well as the major market trends. Aside from the high quality of the presentations and the success of the event, the 200 INAF, industry and governmental participants once again took note of the vitality of the INAF/CQVB partnership, which has now been serving the province’s nutraceutical products and functional foods industry for over five years. The organizers thank the Government of Bavaria, the Consulat général de Belgique-Région Wallone, the Quebec Ministry of Economic development, Innovation and Exportation and the Quebec Ministry of International relations, whose support made it possible to invite the European researchers. The symposium was the first scientific event present within the framework of “IMAGINE! l’Événement de l’innovation”, a regional initiative intended to promote science and technology in the Quebec City region. The Symposium showcased not only the most recent work under each of the major themes of INAF research, but also what is being done elsewhere and the major market trends More than 225 participants from all units of INAF, from industry, government and partner organizations took part in the INAF Symposium A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 INAF Events Nutra-Innovation Network Eliminating trans fats: Why and how? Nutra-Innovation Network technology meeting February 22, 2006, Hotel L’Oiselière, Lévis Most dietary trans fat comes from hydrogenated vegetable oils used in a multitude of products of all categories. Since consumers are becoming more and more demanding, the food industry is feeling strong pressure to replace hydrogenated vegetable oils and develop new “healthier” versions of their products. This meeting thus united more than 70 participants to hear experts from Quebec, Canada and the United States propose alternatives that are safe for consumers and viable for the industry. Nutrigenomics: myth or reality Nutra-Innovation Network technology meeting May 23, 2006, Hotel Gouverneur Ile Charron, Longueuil The following strategic partnerships were maintained over the course of the year 2005-2006 Nutrigenomics appears to bear the promise of better identification of persons at risk of developing illnesses such as cancer, cardiovascular disease, diabetes or obesity and of better guidance of dietary choices for the prevention of these diseases. Private companies already offer genetic screening services in order to promote dietary choices adapted to the genetic constitution of their clients. However, widespread use of this science raises major ethical, economic and social considerations. Seven expert speakers assembled for the occasion from Quebec, Canada and the United States discussed these subjects with realism and objectivity. About sixty people attended the meeting. Nutra-Innovation Network The aim of the activities of the NutraInnovation Network is to provide opportunities for matching the interests of scientists, industry and other actors in the nutraceutical products and functional foods sector. The high level of participation and great success of Nutra-Innovation Network activities, combined with a growing need for information in the industry, have led the CQVB to create a full-time position for the coordination of the activities of the Nutra-Innovation Network. Ms. Isabelle Marquis has thus taken over from Ms. Sophie Banville as director of the Nutra-Innovation Network. www.cqvb.qc.ca Left to right: David Forster (R&D, Bunge Canada), Khaled Belkacemi (INAF, Université Laval), Lydia Dumais (Nutritional labelling and health claims, Health Canada), Tom Tiffany (ADM Food Oils R&D), Johanne Tanguay (Cintech Agroalimentaire), Benoît Lamarche (INAF, Université Laval) and Nimal Ratnayake (Nutritional research division, Health Canada) Left to right: Marc-André Sirard (CRBR, U. Laval), Marie-Claude Vohl (INAF, U. Laval), Christian Brouillette (Neptune Technologies & Bioressources Inc., Montréal), Béatrice Godard (Centre de recherche en droit public, U. de Montréal), Louis Pérusse (Faculty of medicine, U. Laval), Ahmed El-Sohemy (Canada Research Chair in Nutrigenomics, U. of Toronto), Rosalynn Gill-Garrison (Sciona Inc., United States). Passeport Santé INAF continued the writing and scientific editing of the texts in the Health section of the Food Encyclopaedia at this website intended for the general public. Ms. Louise Corneau coordinated the composition and editing of all the product profiles, a very rigorous exercise that involved the participation of several INAF researchers and nutritionists. www.passeportsante.net Nutra + Analytical services Long-time partner of INAF, TransBIOTech offers a whole range of R&D services to businesses in the agri-food and health sectors. In addition to scientific partnerships and research projects, INAF and TransBIOTech have developed a portfolio of joint services intended for industry. www.tbt.qc.ca/nutraplus/index.html 23 INAF A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 Events Lectures and seminars August 23, 2005 Physical gels and complexes formed by hydrophobic association between globular proteins and amphiphilic polyacrylates Christophe TRIBET, Ph.D., Physical chemistry of polymers and dispersed media, Centre national de la recherche scientifique UMR 7615, Paris, France October 12, 2005 Development, validation and application of a new in vitro intestinal fermentation model with immobilized faecal micro-biota Gwenaelle Le Blay, Ph.D., Institute of Food Science and Nutrition, Swiss Federal Institute of Technology Zurich, Zurich, Suisse October 27, 2005 Cellular mechanisms for insulin resistance in skeletal muscles and effects of contraction: Studies in rats fed with carbohydrate solutions or treated with dexamethasone Gwenaelle Le Blay (middle) felt at home, having done a post-doc at the STELA centre directed by researcher Ismaïl Fliss (on her left) at the beginning of the decade. On her right is INAF’s deputy director, Ms. Renée Michaud. Junior 1 FRSQ clinical research fellow Dr. France Légaré appears on the right accompanied by Sylvie Dodin, holder of the Lucie and André Chagnon chair for integrated approaches in disease prevention. December 9, 2005 March 31, 2006 The impact of diet on metabolic syndrome and obesity-linked type-2 diabetes The effects of flaxseed on cardiovascular disease November 2, 2005 Livar Frøyland, Ph.D., director of research, National Institute of Nutrition and Seafood Research, professor of nutritional physiology at the Faculty of medicine at University of Bergen, Norway In collaboration with the Centre de recherche sur les maladies lipidiques de l’Université Laval Whole grains, fibres and management of illnesses and health December 15, 2005 Jérôme Ruzzin, Ph.D., Department of physiology, National Institute of Occupational Health, University of Sports, Oslo, Norway Thomas Wolever, Ph.D., MD, professor, Department of nutritional sciences, University of Toronto, Toronto, Canada In collaboration with Le pain Bon Matin November 23, 2005 What is wrong with the diet of modern Homo sapiens? Avenues for making better choices Michel Lucas, Dt.P., M.Sc., Centre de recherche de l’Hôpital Saint-François d’Assise Ingredience or how to talk about taste, good living and healthy diet to today’s consumers Frédéric Blaise, Dt.P., president of Enzyme Communication Marketing In collaboration with Le Commensal 24 The brain of plants: Neurotransmitters, neurotoxins and neuroregulators Susan J. Murch, Ph.D., Assistant Professor & Canada Research Chair in Natural Products Chemistry, University of British Columbia, Kelowna, Canada In collaboration with the Horticulture Research Centre of Université Laval Grant Pierce, Ph.D., MD, Faculty of medicine of the University of Manitoba, St. Boniface General Hospital Research Centre In collaboration with the department of pharmacology at Université de Montréal April 13, 2006 Decision sharing in health: concepts, measures and interventions France Légaré, Ph.D., MD, researcher at Centre hospitalier universitaire de Québec, Hôpital St-François D’Assise, family medicine unit and evaluative research unit In collaboration with the Lucie and André Chagnon foundation for integrated approaches in disease prevention January 30, 2006 Nutrition of the brain during aging: Challenges and opportunities Dr Stephen Cunnane, Ph.D., Research Center on Aging, University of Sherbrooke Institute of Geriatrics In collaboration with the Lucie and André Chagnon chair for integrated approaches in disease prevention Dr. Grant Pierce is chief editor of the Canadian Journal of Physiology and Pharmacology and a recognized researcher in the field of functional foods and nutraceutical products. A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 INAF INAF partners Organizations and industry partners The following list includes private businesses and organizations that have contributed by direct funding or in kind to carrying out research projects in collaboration with INAF members. ABK Gaspésie DMV International Les Producteurs laitiers du Canada Advitech Dupont Canada Inc. Les Serres du St-Laurent (Savoura) Agribrands Purina International Eurodia Les Viandes du Breton Agropur coopérative Enzymotec Margarine Thibault Algatek Fédération des producteurs de bovins du Québec Medicago Aliments Ultima American Egg Board Ameridia Fédération des producteurs de lait du Québec Merck Frosst Canada MR Nature inc. MuscleTech Research & Development Argousier Lac St-Jean Fédération des producteurs de porcs du Québec Association des producteurs de canneberges du Québec Flax Council of Canada Nature 3M inc. Fondation Lucie et André Chagnon Nestec Fournier Pharma Nestlé Forbes Medi-Tech Novableu Fumoirs Grizzly Novalait Grober Nutrition Nutravital Groupe Danone Ocean Spray Canada Harmonium International Omega Protein Hydro-Québec Parmalat Canada Immunotec Peros Ingrédia Pfizer Canada Innodia Provigo Institut Rosell Pulse Canada ISM Biopolymer PureCell Technologies Isodis Natura SIM Composite Lab-eaux-Bioscience Marine Solvay Pharma Laiterie Lamothe et Frères Ltée Sonertec Leprino Foods Sulzer Les Biotechnologies Oceanova Tetrapak Canada Les Fraises de l’Ile d’Orléans Unilever Canada Les Fromages Saputo Ltée Whitehall Robbins Les Industries Lassonde Wyeth-Ayerst Canada Association des producteurs d’argousier du Québec Atrium Biotechnologies Axcan Pharma inc. Biogenic Foods inc. Biolactis Bohringer Ingelheim Brochu-Lafleur Bunge Foods Canada/USA Canneberges Atoka Canadian Inovatech Inc. Caravelle Foods Centre de recherche en acériculture (ACER) Centre de développement du porc du Québec Coalition canadienne des producteurs de canneberges Commission canadienne du lait Coopérative Fédérée de Québec CRÉA Biopharma Damafro Naturia 25 INAF A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 INAF partners Organizations and industry partners The following list includes private businesses and organizations that contributed direct funding or in kind to activities pertaining to organizational development, communication and transfer in collaboration with INAF members. Advanced Foods and Materials Network (AFMnet) Agriculture et Agroalimentaire Canada Association pour les ingrédients santé en alimentation (AISA) Centre de formation professionnelle Fierbourg Consulat général de Belgique Région Wallone Centre québécois de valorisation des biotechnologies (CQVB) Développement économique Canada (DEC) Direction régionale de la Capitale-Nationale du MAPAQ Ministère de l’Agriculture, des Pêcheries et de l’Alimentation du Québec (MAPAQ) Ministère du Développement économique, de l’Innovation et de l’Exportation (MDEIE) Ministère des Relations internationales du Québec (MRI) Passeport Santé Pôle Québec Chaudière-Appalaches Richardson Centre for Functional Foods and Nutraceuticals du Manitoba Société internationale des sciences horticoles TransBIOTech Fédération internationale de laiterie (FIL) Fondation Lucie et André Chagnon pour une approche intégrée en prévention Gouvernement de la Bavière La Fondation des Gouverneurs Le Commensal Le Pain Bon Matin Note: The list of granting agencies is in appendix to the grants section. 26 Research projects . . . . . . . 28 Published papers . . . . . . . . 40 Communications . . . . . . . . . 47 Student projects . . . . . . . . . 56 APPENDICES A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 INAF 27 INAF A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 Team grants Source of funding Name of program Title of project Researcher(s) Total amount ($) Period Affaires étrangères Canada Échange France - Québec Modèle in vitro de digestion Subirade, Muriel*, Angers, Paul Fliss, Ismail 20 000 2006 - 2007 CDA Applied Research Increasing the consumption of fruits and vegetables for weight management in postmenopausal obese women Lemieux, Simone* 91 904 Bégin, Catherine, Weisnagel, John E. Provencher, Véronique 2005 - 2007 Rigorous scientific evaluation of selected antidiabetic plants Haddad, Pierre Sélim* Arnason, J.T., Prentki, M. 150 000 2003 - 2005 CDA CORPAQ Demande sociétale Minéraux nutritifs nanocristallins comme alternative à l’emploi des agents de conservation synthétiques dans les jus de fruits Arul, Joseph* Belkacemi, Khaled 96 000 2006 - 2008 CORPAQ Programme développement expérimental - Partenariat Évaluation du potentiel nutraceutique des algues marines du Québec Turgeon, Sylvie* Boulanger, Rénald 78 261 2002 - 2006 CORPAQ Projet partenariat Bioingrédients à base de bactériocines de bactéries lactiques et conservation des produits marins Fliss, Ismail* Lacroix, Christophe, Smith, J. Desbiens, M. 80 003 2002 - 2005 Crohn’s & Colitis Foundation of Canada - Paraoxonase: intestinal localization, genetic-environmental regulation and its role in Crohn’s disease Levy, Emile Haim* Seidman, E. Sinnet, D. 444 000 2005 - 2007 Functional food and nutraceuticals: opinions of Quebec physicians and nutritionists West, Gale*, Dodin, Sylvie Lemieux, Simone Larue, Bruno 118 303 2002 - 2005 2 125 000 2006 - 2011 CRSH CRSNG Chaire industrielle Chaire de recherche CRSNG-industrie laitière en technologie et typicité fromagère Roy, Denis* CRSNG Programme de recherche concertée sur la santé (PRCS) Efficacité de bactériocines sur les pathologies fongiques Rouabhia, Mahmoud* Fliss, Ismail, Subirade, Muriel 214 851 2005 - 2008 CRSNG Programme de recherche concertée sur la santé (PRCS) Développement de biomatériaux à partir des protéines de grandes cultures Subirade, Muriel* Rouabhia, Mahmoud Mateescu, Mircea A. 300 001 2004 - 2007 CRSNG Projets stratégiques (SPS) Analyse génomique de la performance industrielle de ferments lactiques dans la fabrication fromagère LaPointe, Gisèle* Roy, Denis 453 506 2005 - 2008 CRSNG Projets stratégiques (SPS) Enrichissement des jus de fruits par des composés nutraceutiques encapsulés Makhlouf, Joseph* Turgeon, Sylvie Vuillemard, Jean-Christophe 334 119 2002 - 2007 CRSNG Projets stratégiques (SPS) Exploration du métagénome de la microflore associée aux systèmes de collecte de l’eau d’érable et détermination de son impact sur la qualité des produits de l’érable Roy, Denis* LaPointe, Gisèle 317 502 2004 - 2007 CRSNG Projets stratégiques (SPS) Development of a new protein/polysaccharide Turgeon, Sylvie* functional ingredient St-Gelais, Daniel 378 425 2002 - 2006 CRSNG Recherche et Développement Coopératif (RDC) Facteurs de croissance du lait bovin : extraction, caractérisation et activités biologiques 1 356 072 2005 - 2008 AAC : Agriculture et Agroalimentaire Canada CDA : Association canadienne du diabète CORPAQ : Conseil de recherche en pêche et agroalimentaire du Québec CRSH : Conseil de recherches en sciences humaines du Canada 28 FCI : Fondation canadienne pour l’innovation (FCI) FQRNT : Fonds québécois de la recherche sur la nature et les technologies FQRSC : Fonds québécois de la recherche sur la société et la culture Gauthier, Sylvie F.*, Pouliot, Yves Turgeon, Sylvie Poubelle, Patrice FRSQ : Fonds de la recherche en santé du Québec IRSC : Instituts de recherche en santé du Canada * Main research director A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 INAF Team grants Source of funding Name of program Title of project Researcher(s) Total amount ($) Period CRSNG Recherche et Développement Coopératif (RDC) Caractérisation, valorisation et transformation de l’argousier du Québec Ratti, Cristina*, Belkacemi, Khaled Makhlouf, Joseph 120 000 2005 - 2007 CRSNG Recherche et Développement Coopératif (RDC) Polysaccharides et dérivés bioactifs issus de Laminaria longicruris Turgeon, Sylvie* Roy, Denis 427 645 2006 - 2009 Fond. maladies du coeur du Canada Clinical cardiovascular and cerebrovascular research... Marqueurs non traditionnels des maladies cardiovasculaires et graines de lin broyées versus placebo chez les femmes ménopausées : une étude satellite Dodin, Sylvie* Jacques, Hélène, Lemay, André Forest, Jean-Claude Légaré, France, Masse, Benoît 45 000 2002 - 2005 Fond. maladies du coeur du Canada Strategic Initiative Clinical evaluation to improve obesity intervention prescription: Functional foods as a potential solution for low satiety quotient phenotype? Tremblay, Angelo* Després, Jean-Pierre, Richard, Denis Lamarche, Benoît Blundell, John E. 54 002 2004 - 2007 Fondation du cancer du sein de Montréal - Millepertuis et les symptômes de ménopause Dodin, Sylvie* chez les femmes souffrant de cancer Provencher, Louise du sein : une étude de faisabilité Verreault René, Otis, Hélène 89 218 2002 - 2005 FQRNT Action concertée - Sciences et technologies de la mer Développement d’un procédé économique pour le chitosane et le carbonate de calcium monoparticulaire Arul, Joseph* Belkacemi, Khaled 192 000 2004 - 2007 FQRNT Action concertée FQRNT Novalait - MAPAQ - AAC Régulation électrochimique du potentiel d’oxydoréduction du lait : impact sur l’efficacité de transformation et la qualité des produits Britten, Michel*, Angers, Paul Bazinet, Laurent, Pouliot, Yves Champagne, Claude P. Vuillemard, Jean-Christophe 250 000 2003 - 2006 FQRNT Action concertée FQRNT Novalait - MAPAQ - AAC Interactions acide folique-vitamine Girard, Christiane* B12-méthionine : effets sur le métabolisme Thivierge, Carole hépatique et la productivité chez les vaches laitières 375 000 2003 - 2006 FQRNT Action concertée FQRNT Novalait - MAPAQ - AAC Pour un meilleur contrôle des aptitudes technologiques du lait de fromagerie grâce au développement de méthodes moléculaires du suivi et de la quantification de l’activité microbiologique LaPointe, Gisèle*, Roy, Denis St-Gelais, Daniel 375 002 2004 - 2007 FQRNT Action concertée FQRNT Novalait - MAPAQ - AAC Valorisation du potentiel de Streptococcus thermophilus par une meilleure connaissance du métabolisme des sucres Vadeboncoeur, Christian* 388 501 Britten, Michel, Moineau, Sylvain Frenette, M., Robitaille, G., St-Gelais, D. 2002 - 2005 FQRNT Action concertée FQRNT Novalait - MAPAQ - AAC Caractérisation des activités biologiques et du potentiel technologique de souches bactériennes isolées de ferments lactiques naturels Vuillemard, Jean-Christophe* Champagne, Claude P. St-Gelais, Daniel 283 500 2003 - 2006 FQRNT Action concertée FQRNT Novalait - MAPAQ - AAC Facteurs influençant la teneur en protéines et lipides du lait des fermes du Québec Wade, K.*, St-Gelais, Daniel 375 002 Turgeon, Sylvie, Lacroix, R., Ouellet, D. 2004 - 2007 FQRNT Action concertée Sciences et technologies de la mer Développement de biofilms à base de bactériocines et de chitosane pour l’inactivation de la microflore pathogène et d’altération des produits marins Fliss, Ismail* Boutin, Yvan Subirade, Muriel 210 000 2003 - 2006 FQRNT Action concertée - Sciences et technologies de la mer Optimisation et rationalisation électrodialytique de la transformation du chitosane en oligomères Bazinet, Laurent* Arul, Joseph 195 001 2004 - 2007 FQRNT Action concertée - Recherche sur les aliments fonctionnels Ingrédients nutraceutiques du gras laitier, enrichis en acides linoléiques conjugués et acide vaccénique : production, utilisation et effets bénéfiques contre les maladies neurodégénératives Arul, Joseph*, Angers, Paul Belkacemi, Khaled Chouinard, Yvan Haddad, Pierre Sélim Ramassamy, Charles 224 002 2003 - 2006 MAPAQ : Ministère de l’Agriculture, des Pêcheries et de l’Alimentation du Québec MDEIE : Ministère du Développement économique, de l’Innovation et de l’Exportation MEQ : Ministère de l’Éducation du Québec MRI : Ministère des Relations internationales du Québec NIH : National Institutes of Health (USA) PLC : Les producteurs laitiers du Canada RCE : Réseau des centres d’excellence fédéral UPA : Union des producteurs agricoles VRQ : Valorisation Recherche Québec * Main research director 29 INAF A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 Team grants Source of funding Name of program Title of project Researcher(s) Total amount ($) Period FQRNT Action concertée - Recherche sur les aliments fonctionnels Identification de composantes immunomodulantes dans les produits à base de protéines de lactosérum Gauthier, Sylvie F.* Boutin, Yvan Fliss, Ismail 221 338 2003 - 2008 FQRNT Action concertée - Recherche sur les aliments fonctionnels Lyophilisation par moussage : une nouvelle approche pour réduire le temps de lyophilisation Ratti, Cristina* Makhlouf, Joseph 225 000 2003 - 2006 FQRNT Action concertée - Recherche sur les aliments fonctionnels Nutraceutiques et aliments fonctionnels : indicateurs de performance et facteurs clés de succès de l’industrie au Québec Saives, Anne-Laure Cloutier, Martin* Delorme, M. 196 530 2004 - 2006 FQRNT Action concertée - Recherche sur les aliments fonctionnels Développement de véhicules nano et microparticules pour préserver les fonctions de molécules nutraceutiques et optimiser leur biodisponibilité : application aux antioxydants naturels Subirade, Muriel* Angers, Paul Ramassamy, Charles Beysac, E. Thibodeau, Alain 225 003 2003 - 2006 FQRNT Forêt boréale et son écologie au Saguenay Lac Saint-Jean Valorisation de l’écorce d’épinette noire et de peuplier faux-tremble Cloutier, Alain Stevanovic, Tatjana 195 000 2004 - 2007 FQRNT Projet de recherche en équipe Développement et validation de stratégies Jean, Julie* moléculaires pour la concentration et la Fliss, Ismail détection des norovirus dans des échantillons hydriques, environnementaux, alimentaires et cliniques 145 000 2005 - 2008 FQRNT Projet de recherche en équipe Mise au point et caractérisation d’un chélateur de la gliadine Subirade, Muriel, Rivard, Nathalie Leroux, Jean-Christophe* 120 002 2006 - 2009 FQRSC Soutien aux équipes de recherche Performance, modélisation, coordination et transformation des entreprises de biotechnologie Cloutier, Martin* Saives, Anne-Laure 463 001 2006 - 2010 FRSQ Clinical Research Cholesterol level and suicide behavior: A clinical and molecular study Gustavo, Turecki Levy, Emile Haim 270 000 2004 - 2007 FRSQ Projet pilote Mise au point d’aliments contenant du xylitol pour un projet visant à réduire l’incidence de la carie chez les jeunes enfants québécois à risque Giasson, Luc* Lemieux, Simone Turgeon, Sylvie Gagnon, P. 8 560 2006 Hospital for Sick Children Sick kids Foundation Omega-3 fatty acids and prematurity Dodin, Sylvie*, Cunnane, Stephen Dewailly, Éric, Piedboeuf, Bruno Marc, Isabelle, Lucas, Michel Muckle Gina, Tessier, Réjean 118 622 2006 - 2007 IRSC - Inuit health in transition study: Omega-3 fatty acids and oxidative stress in obese and diabetic inuit subjects Julien, Pierre Dewailly, Éric 89 566 2005 - 2006 IRSC - Obesity and cardiovascular risk factors in children and adolescents Lambert, Marie* Levy, Emile Haim 190 562 2004 - 2006 IRSC - Role of peroxides generated in multivitamin Lavoie, J.C. solutions on the initiation of complications Levy, Emile Haim of parenteral nutrition 376 003 2002 - 2005 IRSC - Intestinal fat transport in the developing intestine: mechanisms regulating apolipoprotein B-containing lipoprotein assembly and secretion Levy, Emile Haim* Delvin, Edgard, Chessex, P. Alvarez, F. 492 000 2002 - 2007 IRSC - Intestinal scavenger receptor class B type I (SR-BI): Topology on brush-border membrane, regulatory mechanisms and role in cellular cholesterol metabolism Levy, Emile Haim* Delvin, Edgard 443 997 2004 - 2009 AAC : Agriculture et Agroalimentaire Canada CDA : Association canadienne du diabète CORPAQ : Conseil de recherche en pêche et agroalimentaire du Québec CRSH : Conseil de recherches en sciences humaines du Canada 30 FCI : Fondation canadienne pour l’innovation (FCI) FQRNT : Fonds québécois de la recherche sur la nature et les technologies FQRSC : Fonds québécois de la recherche sur la société et la culture FRSQ : Fonds de la recherche en santé du Québec IRSC : Instituts de recherche en santé du Canada * Main research director A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 INAF Team grants Source of funding Name of program Title of project Researcher(s) Total amount ($) Period IRSC - Functional and physiopathological development of the gastro-intestinal tract Ménard, D.* Levy, Emile Haim et coll. 969 585 2001 - 2006 IRSC CIHR Strategic Initiatives HIV/AIDS Research Program Cardiovascular effects of n-3 polyunsaturated fatty acids in dyslipidemic HIV-infected patients Couture, Patrick* Lamarche, Benoît 210 512 2005 - 2008 IRSC New Emerging Team Familial study on the prevention of Lambert, Marie* cardiovascular disease and type 2 diabetes Levy, Emile Haim in children and adolescents. Tremblay, Angelo et coll. 979 882 2004 - 2009 IRSC New Emerging Team Gene-environment interactions in obesity: Integration of genetic information into the prevention and treatment of obesity 1 395 001 2003 - 2008 IRSC New Emerging Team - Institute Rigorous scientific evaluation of selected of Aboriginal Peoples Health antidiabetic plants: Toward an alternative therapy for diabetes in the Cree of Northern Quebec 900 000 2003 - 2006 IRSC Operating Grant Physiological mechanisms underlying Couillard, Charles* the effects of PUFA and antioxidants on Lamarche, Benoît postprandial lipemia, oxidative stress, endothelial dysfunction and inflammation in men 431 820 2005 - 2008 IRSC Operating Grant Effect of dietary antioxidant supplementation Couillard, Charles* on lipoprotein-lipid concentrations, LDL Lamarche, Benoît oxidation, and inflammation in overweight men Lemieux, Simone 199 500 2003 - 2005 IRSC Operating Grant Assessment of insulin sensitivity in insulin- Jacques, Hélène* resistant subjects fed fish proteins Marette, André, Wiesnagel, John E. 270 000 2003 - 2006 IRSC Operating Grant Assessment of the practical application, Jenkins, David* acceptability and effectiveness of a portfolio Jones, Peter diet in reducing serum cholesterol 558 946 2004 - 2006 IRSC Operating Grant Lipoprotein turnover on high and low fat portfolio diets 443 615 2005 - 2008 IRSC Operating Grant Intramyocellular lipids and insulin resistance Joanisse, Denis* Tremblay, Angelo, Marette, André in human obesity and diabetes 346 636 2004 - 2008 IRSC Operating Grant Mechanistic investigation of the mediterranean diet and its impact on the metabolic syndrome in men Lamarche, Benoît* Couture, Patrick 547 376 2006 - 2009 IRSC Operating Grant Endothelial lipase and lipoprotein metabolism in humans Lamarche, Benoît* Couture, Patrick 268 115 2003 - 2006 IRSC Operating Grant Milk consumption and the metabolic syndrome in menopausal women Lamarche, Benoît* Lemieux, Simone, Dodin, Sylvie 182 498 2004 - 2006 IRSC Operating Grant Intervention s’inspirant du nouveau paradigme en matière de gestion de poids chez les femmes préménopausées présentant un surplus de poids Lemieux, Simone* Tremblay, Angelo Boivin, Sonia 218 883 2003 - 2006 IRSC Operating Grant A search for genes influencing human eating behaviors and their role in obesity Pérusse, Louis*, Lemieux, Simone Vohl, Marie-Claude 433 677 2005 - 2009 IRSC Operating Grant Clinical evaluation to improve obesity intervention prescription: Functional foods as a potential solution for low satiety quotient phenotype? Tremblay, Angelo* Lamarche, Benoît, Després, Jean-Pierre Richard, Denis, Blundell, John E. 674 837 2004 - 2008 IRSC Operating Grant Genomic insights into the metabolic syndrome Vohl, Marie-Claude* Tchernof, André 273 138 2004 - 2007 MAPAQ : Ministère de l’Agriculture, des Pêcheries et de l’Alimentation du Québec MDEIE : Ministère du Développement économique, de l’Innovation et de l’Exportation Pérusse, Louis* Vohl, Marie-Claude et coll. Haddad, Pierre Sélim* Arnason, J.T., Cuerrier, A. Dugas, M., Johns, T. Prentki, M. Jenkins, David* Lamarche, Benoît MEQ : Ministère de l’Éducation du Québec MRI : Ministère des Relations internationales du Québec NIH : National Institutes of Health (USA) PLC : Les producteurs laitiers du Canada RCE : Réseau des centres d’excellence fédéral UPA : Union des producteurs agricoles VRQ : Valorisation Recherche Québec * Main research director 31 INAF A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 Team grants Source of funding Name of program Title of project Researcher(s) IRSC Operating, Clinical Trial Effect of a combination of dietary factors (viscous fibers, vegetable proteins and plant sterols) on cholesterol reduction in hyperlipidemic Jenkins, David Lamarche, Benoît IRSC Pilot Project Grant Effects of exercise on energy intake, satiety and hunger at subsequent meal in type 1 and type 2 diabetic individuals Weisnagel, S. John* Tremblay, Angelo IRSC CIHR Team in Aboriginal Antidiabetic Medicines Haddad, Pierre S. et 17 autres chercheurs IRSC Validation of genetic markers of bone density and osteoporosis in a large population-based sample IRSC Bénéfices de l’analgésie non pharmacologique par l’hypnose pour contrôler la douleur lors de l’interruption volontaire de grossesse IRSC Total amount ($) Period 558 946 2004 - 2006 96 839 2006 - 2007 4 500 000 2006 - 2011 Rousseau, F. Dodin, Sylvie 455 136 2003 - 2006 Dodin, Sylvie*, Marc, Isabelle Rainville, P., Verreault, René Masse, Benoît 189 677 2004 - 2005 A link between fetal growth restriction Leduc, L., Delvin, E., Dubé, J. and early onset endothelial cell dysfunction Fouron, J.C., Ghadirian, P., Levy, E. Moutquin, J.M., Tremblay, L. 502 356 2006 - 2010 IRSC Genetic epidemiology of early-onset Amre, D., Deslandres, C. Ccrohn’s disease: Investigating the role of diet Levy, E., Morgan, K. and xenobiotic metabolizing enzyme genes Seidman, E. 382 971 2006 - 2009 IRSC Oxidative stress, fetal growth and programming of the metabolic syndrome Luo, Z.C., Levy, E., Audibert, F. Deal, C., Julien, P. and Fraser, W. 455 000 2006 - 2009 Boutin, Yvan* Gaudreau, Éric Milette, Esther 35 520 2005 - 2006 MEQ Programme aide recherche technologique (PART) Adaptation de méthodes pour évaluer la stabilité et la pharmacodynamique de protéines MEQ Programme aide recherche technologique (PART) Amélioration d’une plateforme d’analyse du Boutin, Yvan* mode d’action d’anti-inflammatoires d’origine L’Homme, Yvan naturelle pour application topique (peau) 36 000 2006 - 2006 MEQ Programme aide recherche technologique (PART) Développement d’une démarche pour identifier les marqueurs biodisponibles Couture, Serge* Boutin, Yvan 79 900 2004 - 2005 MRI Programme de coopération Québec - Mexique Optimisation des conditions d’opération dans le séchage convectif des produits à haute valeur nutraceutique Ratti, Cristina* Makhlouf, Joseph 20 000 2004 - 2006 MRI Programme de coopération Québec - Mexique Valorisation de molécules nutraceutiques extraites de plantes riches en anti-oxydants Subirade, Muriel* Angers, Paul 4 900 2004 - 2006 MRI Projet coopération France Québec Biennum 2004 - 2006 Développement et validation de systèmes Subirade, Muriel* d’administration de levures bioactives Angers, Paul dans l’environnement digestif Fliss, Ismail 8 000 2004 - 2006 NIH Program Grant Effect of black tea consumption on plasma lipids and lipoproteins, brachial artery flowmediated vasodilation and markers of oxidative status in smokers Baer, D.* Jones, Peter 70 000 2004 - 2005 PLC/CRSNG Oxidative and thermal stability of CLA-enriched milk fat fractions and their stabilization against oxidative deteriorations Angers, Paul* Arul, Joseph Belkacemi, Khaled 87 002 2005 - 2007 PLC/CRSNG Value-added processing of lactose: Preparation of bioactive lactobionic acid using a novel catalytic method Belkacemi, Khaled* Arul, Joseph 46 002 2005 - 2007 AAC : Agriculture et Agroalimentaire Canada CDA : Association canadienne du diabète CORPAQ : Conseil de recherche en pêche et agroalimentaire du Québec CRSH : Conseil de recherches en sciences humaines du Canada FCI : Fondation canadienne pour l’innovation (FCI) FQRNT : Fonds québécois de la recherche sur la nature et les technologies FQRSC : Fonds québécois de la recherche sur la société et la culture 32 FRSQ : Fonds de la recherche en santé du Québec IRSC : Instituts de recherche en santé du Canada * Main research director A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 INAF Team grants Source of funding Name of program Title of project Researcher(s) Total amount ($) Period PLC/CRSNG The effect of glutamine supplementation on immunity and productivity in early lactation cows Bernier, Jean Lapierre, Hélène Lessard, Martin 100 001 2005 PLC/CRSNG Effects of various isomers of conjugated linoleic acid on lipoprotein profile and body composition in hamsters Jacques, Hélène* Chouinard, Yvan 13 246 2003 - 2005 PLC/Novalait Study of the impact of trans fatty acids from dairy products Lamarche, Benoît* Chouinard, Yvan, Couture, Patrick Lemieux, Simone, Paquin, Paul 300 000 2005 - 2007 PLC/CRSNG Milk consumption and the metabolic syndrome in menopausal women Lamarche, Benoît*, Dodin, Sylvie, Lemieux, Simone 106 000 2004 - 2005 PLC/CRSNG Activités biologiques des composés mineurs du babeurre et du lactosérum Pouliot, Yves* Gauthier, Sylvie F. 97 560 2006 - 2007 PLC/CRSNG A nutraceutical strategy to improve milk production by controling phosphodiesterase activity in mammary gland Richard, François* Pothier, François Chouinard, Yvan 170 230 2006 - 2008 RCE - AFMnet The beneficial effects of fish nutrients on the obesity-linked metabolic syndrome and cardiovascular risk profile. An integrative genomic and metabolic phenotyping project Holub, Bruce Jacques, Hélène Marette, André* Vohl, Marie-Claude 730 001 2006 - 2009 RCE - AFMnet Use of conjugated linoleic acid as a nutraceutical for health promotion in humans Jones, Peter* Cunnane, Stephen Jacques, Hélène Lamarche, Benoît Marette, André 450 000 2006 - 2009 RCE - AFMnet Use of conjugated linoleic acid as a nutraceutical for weight loss in humans Jones, Peter* Jacques, Hélène, McLord, R. 252 000 2003 - 2006 Vegetable oils as sustainable substitutes to fish oil in salmonid diets: an approach to minimize contaminants and reduce feed costs Vandenberg, G.* Chouinard, Yvan Dewailly, Eric 117 000 2004 - 2006 Programme intégré de soutien à la prise de décision en matière de produits de santé naturels pour les femmes d’âge moyen vivant la transition ménopausique et celles ménopausées Légaré, France* Dodin, Sylvie O’Conor, Annette Richer, M. 47 765 2004 - 2005 RCE - AFMnet AquaNet Santé Canada Santé Canada Natural Health Products Research Program Development of advanced expertise along with effective and rigourous methods to assess probiotic safety, quality and safety Roy, Denis* Amiot, Jean Boutin, Yvan 20 001 2005 - 2006 Santé Canada Programme d’autoapprentissage à l’intention des praticiens alternatifs Lecture critique et gestion de l’information sur les produits de santé naturels Dodin, Sylvie*, Marc, Isabelle Cauchon, M., Ernst, E. 42 640 2004 - 2005 VRQ Volet International Valorisation de la biomasse marine et laitière Lamarche, Benoît* Angers, Paul Arul, Joseph Belkacemi, Khaled Britten, Michel Fliss, Ismail LaPointe, Gisèle Roy, Denis Turgeon, Sylvie 136 500 2005 - 2006 MAPAQ : Ministère de l’Agriculture, des Pêcheries et de l’Alimentation du Québec MDEIE : Ministère du Développement économique, de l’Innovation et de l’Exportation MEQ : Ministère de l’Éducation du Québec MRI : Ministère des Relations internationales du Québec NIH : National Institutes of Health (USA) PLC : Les producteurs laitiers du Canada RCE : Réseau des centres d’excellence fédéral UPA : Union des producteurs agricoles VRQ : Valorisation Recherche Québec * Main research director 33 INAF A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 Individual grants Source of funding Name of program Title of project Agriculture et Agroalimentaire Canada Agriculture Canada, Policy Research Networks/ Université d’Alberta Determinants of consumer intentions to purchase functional foods: The case of omega-3 and lycopene West, Gale 6 000 2005 - 2006 Agriculture et Agroalimentaire Canada Agriculture Canada, Policy Research Networks/ Université d’Alberta Transmission of price trends from consumers to producers West, Gale 23 001 2005 - 2006 CDA - May intestinal lipid contribution constitute Levy, Emile Haim a place of the puzzle in hyperlipidemia characterizing insulin resistance and diabetes 150 000 2004 - 2006 CDA Grant - in - Aid Regulation of glucose metabolism in insulin-target tissues of normal and insulin-resistant animals Marette, André 224 760 2003 - 2006 CDA Operating Role of AMPK and p38 MAPK pathways in exercise-induced glucose transport in skeletal muscle: Potential targets for the treatment of insulin resistance in diabetes Marette, André 75 000 2005 - 2008 CORPAQ Demande sociétale Détection de composantes OGM dans les produits alimentaires du Québec Michaud, Dominique 100 000 2006 - 2008 CRSNG - Energy susbstrate metabolism during healthy aging Cunnane, Stephen 300 000 2003 - 2008 CRSNG De l’idée à l’innovation - INNOV Extraction ultrasonique de molécules Stevanovic, Tatjana lipophiles de deux espèces de la forêt boréale 125 001 2005 - 2006 CRSNG Recherche et Développement Coopératif (RDC) Caractérisation de nouvelles bactériocines Lacroix, Monique produites par des bactéries lactiques d’origine humaine et vérification de leur efficacité à contrôler les infections nosocomiales 59 400 2006 - 2008 CRSNG Recherche et Développement Coopératif (RDC) Composés naturels et leurs utilisations avec l’irradiation Lacroix, Monique 70 971 2005 - 2007 CRSNG Subvention à la découverte Photochemical therapy/ preservation of fresh fruits and vegetables Arul, Joseph 130 000 2003 - 2008 CRSNG Subvention à la découverte Étude du colmatage des membranes en cours de procédés électromembranaires Bazinet, Laurent 120 000 2003 - 2008 CRSNG Subvention à la découverte Hydrogenation of vegetable oils with novel mesostructured catalysts using slurry and monolith reactors Belkacemi, Khaled 103 104 2004 - 2009 CRSNG Subvention à la découverte Nouvelles bactériocines de bifidobactéries Fliss, Ismail 100 001 2003 - 2006 CRSNG Subvention à la découverte Étude des interactions betaLactoglobuline/peptide et leur impact sur les propriétés physico-chimiques et biologiques de cette protéine Gauthier, Sylvie F. 106 300 2002 - 2007 CRSNG Subvention à la découverte Études moléculaires et thermodynamiques de l’attachement des virus entériques aux surfaces et aux aliments Jean, Julie 119 000 2003 - 2007 AAC : Agriculture et Agroalimentaire Canada CDA : Association canadienne du diabète CORPAQ : Conseil de recherche en pêche et agroalimentaire du Québec CRSH : Conseil de recherches en sciences humaines du Canada 34 FCI : Fondation canadienne pour l’innovation (FCI) FQRNT : Fonds québécois de la recherche sur la nature et les technologies FQRSC : Fonds québécois de la recherche sur la société et la culture Researcher(s) Total amount ($) Period FRSQ : Fonds de la recherche en santé du Québec IRSC : Instituts de recherche en santé du Canada A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 INAF Individual grants Source of funding Name of program Title of project CRSNG Subvention à la découverte Mechanisms of action of plant sterols as cholesterol-lowering agents Jones, Peter 144 000 2002 - 2006 CRSNG Subvention à la découverte Évaluation de la radiosensibilisation bactérienne : étude de mécanisme Lacroix, Monique 125 001 2004 - 2009 CRSNG Subvention à la découverte Mécanismes moléculaires de la biosynthèse LaPointe, Gisèle des exopolysaccharides chez les bactéries lactiques et probiotiques 135 000 2004 - 2009 CRSNG Subvention à la découverte A new approach for the fractionation of peptide mixtures Pouliot, Yves 110 553 2002 - 2007 CRSNG Subvention à la découverte NF-kB, apolipoprotéine E et stress oxydatif Ramassamy, Charles 160 001 2002 - 2007 CRSNG Subvention à la découverte Optimization of food preservation processes using the glass transition temperature concept Ratti, Cristina 116 001 2001 - 2005 CRSNG Subvention à la découverte Étude de la biosynthèse et de la dégradation des polysaccharides par les probiotiques à des fins d’utilisation Roy, Denis 100 000 2004 - 2008 CRSNG Subvention à la découverte Etude des interactions protéines/polysaccharides Turgeon, Sylvie 132 876 2002 - 2007 CRSNG Subvention à la découverte High temperature degradation of fatty acids: A mechanistic study of cyclization and conjugation Angers, Paul 140 000 2004 - 2009 CRSNG Subvention à la découverte Nutrition lipidique chez le ruminant en lactation Chouinard, Yvan 126 400 2002 - 2006 CRSNG Subvention à la découverte Rôle de la protéine d’arachide sur le risque cardiovasculaire et l’homéostasie du muscle squelettique Jacques, Hélène 184 751 2004 - 2009 CRSNG Subvention à la découverte Transport phenomena during drying of complex soft systems Ratti, Cristina 160 001 2005 - 2010 CRSNG Subvention à la découverte Bacterial stress response and efficiency of antimicrobial systems used in food Saucier, Linda 68 000 2002 - 2006 CRSNG Subvention à la découverte Étude des lignines et des polyphénols du bois et de leur importance Stevanovic, Tatjana 80 004 2003 - 2007 CRSNG Subvention à la découverte Étude des mécanismes moléculaires responsables de la stabilisation de systèmes à la base de nouveaux aliments Subirade, Muriel 195 000 2005 - 2010 CRSNG Subvention à la découverte Étude des réseaux protéiques et de leurs Subirade, Muriel mécanismes de formation par spectroscopie infrarouge à transformée de Fourier 68 000 2001 - 2005 CRSNG Subvention à la découverte Régulation du transport intraentérocytaire Levy, Emile des lipides par les hormones gastrointestinales (GLP-1, GLP-2, PYY et Ghréline) 142 500 2006 - 2011 Fond. maladies du cœur du Canada Operating Grant Role of endothelial NO in vascular and metabolic dysfunctions related to insulin resistance 54 003 2004 - 2007 MAPAQ : Ministère de l’Agriculture, des Pêcheries et de l’Alimentation du Québec MDEIE : Ministère du Développement économique, de l’Innovation et de l’Exportation Researcher(s) Bachelard, Hélène MEQ : Ministère de l’Éducation du Québec MRI : Ministère des Relations internationales du Québec NIH : National Institutes of Health (USA) PLC : Les producteurs laitiers du Canada Total amount ($) Period RCE : Réseau des centres d’excellence fédéral UPA : Union des producteurs agricoles VRQ : Valorisation Recherche Québec 35 INAF A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 Individual grants Source of funding Name of program Title of project Researcher(s) Total amount ($) Period Fond. maladies du cœur du Canada Operating grant A human study of the role of the ldl receptor in apolipoprotein b100 secretion Couture, Patrick 51 000 2003 - 2006 Fond. maladies du cœur du Canada Operating Grant Effects of plant sterols and exercise training on plasma lipid levels Jones, Peter 54 000 2004 - 2007 Fond. maladies du cœur du Canada Operating Grant Satiety and energy expenditure enhancement actions of diacylglycerol oil Jones, Peter 70 000 2006 - 2008 Fondation Lucie et André Chagnon Chaire de recherche L’enseignement d’une approche intégrée en prévention Dodin, Sylvie 1 920 000 2002 - 2007 FQRNT Établissement de nouveaux chercheurs (fonctionnement) Mise au point et étude d’un procédé Bazinet, Laurent d’électromigration permettant la séparation, la purification et le fractionnement des isoflavones du soya 45 000 2002 - 2005 FQRNT Établissement de nouveaux chercheurs (fonctionnement) Études moléculaires et thermodynamiques de l’attachement des virus entériques aux surfaces et aux aliments Jean, Julie 45 003 2003 - 2006 FQRNT Établissement de nouveaux chercheurs (fonctionnement) Nouvelles stratégies pour assurer l’innocuité et la salubrité de la viande Saucier, Linda 41 071 2003 - 2006 FQRSC Établissement de nouveaux chercheurs (fonctionnement) Territoire et compétitivité des entreprises de biotechnologies Saives, Anne-Laure 39 002 2004 - 2007 FRSQ Chercheur - boursier Junior 2 Caractérisation et compréhension des effets d’interventions nutritionnelles sur les stress oxydatif, l’information et la fonction endothéliale chez l’humain Couillard, Charles 200 000 2006 - 2010 IRSC Operating Grant Endothelial function and vascular and metabolic responses to insulin in conscious normal rats and insulin-resistant rats. Effects of high sucrose and high fat diets Bachelard, Hélène 264 003 2003 - 2006 IRSC Operating Grant Impact of weight loss on lipid kinetics in overweight, hyperlipidemic women Jones, Peter 281 101 2002 - 2005 IRSC Operating Grant Role of iNOS in the pathogenesis of insulin resistance Marette, André 750 000 2001 - 2006 IRSC Operating Grant Role of iNOS in the pathogenesis of insulin resistance Marette, André 842 971 2006 - 2011 IRSC Operating Grant Role of mTOR in insulin resistance Marette, André 273 000 2002 - 2005 IRSC Operating Grant Role of mTOR/S6K1 in the pathogenesis of insulin resistance Marette, André 735 000 2005 - 2010 IRSC Operating Grant The diabetogenic potential of abdominal adipocytes in women with male-pattern obesity Tchernof, André 331 380 2003 - 2006 IRSC Planning & Development Grants - Collaborative research in the study International Opportunity of human obesity Tremblay, Angelo 24 781 2004 - 2006 IRSC Santé Canada - IRSC. Natural Health Product Directorate Interactions of a standardized ginkgo Ramassamy, Charles biloba extract EGb 761 with pharmacological compounds, foods and NHPs 155 472 2005 - 2008 IRSC Operating Grant Omega-3 fatty acids, brain glucose uptake and cognition in the elderly 327 000 2006 - 2009 AAC : Agriculture et Agroalimentaire Canada CDA : Association canadienne du diabète CORPAQ : Conseil de recherche en pêche et agroalimentaire du Québec CRSH : Conseil de recherches en sciences humaines du Canada 36 FCI : Fondation canadienne pour l’innovation (FCI) FQRNT : Fonds québécois de la recherche sur la nature et les technologies FQRSC : Fonds québécois de la recherche sur la société et la culture Cunnane, Stephen FRSQ : Fonds de la recherche en santé du Québec IRSC : Instituts de recherche en santé du Canada A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 INAF Individual grants Source of funding Name of program Title of project Researcher(s) Total amount ($) Period MAPAQ Direction de l’innovation et des technologies Formulation d’un milieu de culture à base Beaulieu, Lucie d’hydrolysats enzymatiques de poissons et de co-produits marins 48 501 2006 - 2008 MAPAQ Direction de l’innovation et des technologies Production et identification de peptides bio-actifs à partir de co-produits marins Beaulieu, Lucie 39 151 2005 - 2006 MEQ Programme aide recherche technologique (PART) Développement d’un test d’allerginicité du chitosan Boutin, Yvan 18 000 2005 - 2006 Office canadien de commercialisation des œufs (Ontario) Grant in Aid The effect of plant sterols on egg laying hen plasma and egg yolk cholesterol concentrations Jones, Peter 35 451 2006 - 2007 PLC/CRSNG Intestinal cell differentiation, HDL production Levy, Emile Haim and Apo A-I synthesis: Regulation by retinoic acid and n-3 fatty acids 135 332 2005 - 2006 RCE - AFMnet Evaluation of very long chain fatty Jones, Peter acids/alcohol and plant sterols as functional food ingredients for cholesterol-lowering in hypercholesterolemic humans 266 002 2004 - 2006 Santé Canada Modules d’auto-apprentissage à Dodin, Sylvie l’intention des praticiens alternatifs : lecture critique et gestion de l’information sur les produits de santé naturels 42 640 2004 - 2005 25 000 2005 1 400 000 2003 - 2010 500 000 2001 - 2011 1 400 000 2003 - 2010 Santé Canada Natural Health Products Research Program Oméga-3, santé cardiovasculaire et mentale : les experts se prononcent Dodin, Sylvie Secrétariat des chaires de recherche du Canada Programme des chaires de recherche du Canada Brain metabolism and aging Cunnane, Stephen Secrétariat des chaires de recherche du Canada Programme des chaires de recherche du Canada Nutrition et santé cardio-vasculaire Lamarche, Benoît Secrétariat des chaires de recherche du Canada Programme des chaires de recherche du Canada Biotechnologies des cultures lactiques d’intérêt laitier et probiotique Roy, Denis Secrétariat des chaires de recherche du Canada Programme des chaires de recherche du Canada Protéines, bio-systèmes et aliments fonctionnels Subirade, Muriel 500 005 2006 - 2011 Secrétariat des chaires de recherche du Canada Programme des chaires de recherche du Canada Activité physique, nutrition et bilan énergétique Tremblay, Angelo 1 400 000 2003 - 2010 VRQ - Étude du rôle des marqueurs biochimiques Dodin, Sylvie et génétiques dans la prédiction du risque d’ostéoporose et de la réponse au traitement 43 440 2002 - 2006 MAPAQ : Ministère de l’Agriculture, des Pêcheries et de l’Alimentation du Québec MDEIE : Ministère du Développement économique, de l’Innovation et de l’Exportation MEQ : Ministère de l’Éducation du Québec MRI : Ministère des Relations internationales du Québec NIH : National Institutes of Health (USA) PLC : Les producteurs laitiers du Canada RCE : Réseau des centres d’excellence fédéral UPA : Union des producteurs agricoles VRQ : Valorisation Recherche Québec 37 INAF A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 Infrastructure and equipment grants Source of funding Name of program Title of project Researcher(s) Total amount ($) Period CRSNG Équipement A microplate reader Sylvestre, Michel Ramassamy, Charles 50 000 2005 - 2006 CRSNG Équipement Differential Scanning Calorimeter (DSC) Angers, Paul*, Arul, Joseph Belkacemi, Khaled 91 000 2006 - 2007 CRSNG Équipement Headspace sampler for analysis of volatiles Arul, Joseph*, Belkacemi, Khaled Vuillemard, Jean-Christophe 40 500 2004 - 2005 CRSNG Équipement Séparateur de cellules à billes magnétique Vaillancourt, Cathy*, Devine, Patrick 39 057 Ramassamy, Charles Sanderson, Thomas, Bernier, Jacques Fournier, Michel 2006 - 2007 CRSNG Équipement Spectrofluorometer with fluorescence plate reader Bailey, Janice A. Saucier, Linda 81 312 2005 - 2006 CRSNG Équipement Système de chromatographie liquide à haute performace (HPLC) Gauthier, Sylvie F.* Pouliot, Yves, Turgeon, Sylvie 64 697 2005 - 2006 CRSNG Équipement Système de mesure densitométrique en temps réel Ramassamy, Charles*, Devine, Patrick Charbonneau, Michel, Fournier, Alain Girard, Denis, Sanderson, Thomas Vaillancourt, Cathy 49 600 2006 - 2007 FCI Fonds de la Relève Laboratoire de microbiologie des viandes et validation de procédés Saucier, Linda* 603 629 2005 - 2007 FCI Fonds de la Relève Plateforme d’analyse fine en génomique fonctionnelle Robert, Claude* 292 001 2005 - 2006 FCI Fonds de la Relève Plate-forme d’intelligence stratégique et d’apprentissage distribué sur les entreprises de biotechnologie Saives, Anne-Laure* 635 003 2004 - 2007 FCI Fonds de la Relève Plate-forme pour la recherche de pointe en virologie alimentaire Jean, Julie* 816 077 2004 - 2006 FCI Fonds des Chaires Canada Research Chair Infrastructure Cunnane, Stephen* 332 000 2003 - 2006 FCI Fonds des Chaires Equipements scientifiques de pointe dédiés à la tracabilité moléculaire des bactéries probiotiques présentes dans les aliments fonctionnels et l’écosystème intestinal de l’homme Roy, Denis* 335 713 2003 - 2006 FQRNT Établissement de nouveaux chercheurs Nouvelles stratégies pour assurer l’innocuité et la salubrité de la viande Saucier, Linda* 41 071 2003 - 2008 IRSC Equipment Maintenance Gas Chromatography-CombustionIsotope Ratio Mass Spectrometer Pencharz, Paul* Cunnane, Stephen 60 000 2005 - 2006 IRSC Infrastructure Support Imaging Platform Integrated multi-modality molecular... Lecomte, Roger* Cunnane, Stephen 625 000 2006 - 2011 IRSC Training Program Grant A multidisciplinary research training program in digestive sciences Paterson, William* Haddad, Pierre Sélim et 21 autres chercheurs 1 800 000 2002 - 2007 IRSC Training Program in Obesity/Healthy Body Weight Multidisciplinary training program in obesity/healthy body weight Richard, Denis* Marette, André et 8 autres chercheurs 1 480 000 2003 - 2008 AAC : Agriculture et Agroalimentaire Canada CDA : Association canadienne du diabète CORPAQ : Conseil de recherche en pêche et agroalimentaire du Québec CRSH : Conseil de recherches en sciences humaines du Canada 38 FCI : Fondation canadienne pour l’innovation (FCI) FQRNT : Fonds québécois de la recherche sur la nature et les technologies FQRSC : Fonds québécois de la recherche sur la société et la culture FRSQ : Fonds de la recherche en santé du Québec IRSC : Instituts de recherche en santé du Canada * Main research director A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 INAF Operating grants Source of funding Name of program Title of project Total amount ($) Tous Period FQRNT Regroupement stratégique Université Laval - BDR Institut Université Laval - BDR Centre STELA FCI Fonds d’exploitation des infrastructures Appareillage de pointe pour l’étude des Bazinet, Laurent* phénomènes électrodialytiques et de leur impact sur les composantes bio-alimentaires FCI Fonds d’exploitation des infrastructures Recherche sur les modifications des corps gras et autres composés alimentaires améliorant leur valeur nutritionnelle et leur valorisation : réactions chimiques à l’aide de catalyseurs Belkacemi, Khaled* 84 489 2004 - 2009 FCI Fonds d’exploitation des infrastructures Mise en place d’une plateforme pour la recherche de pointe en virologie alimentaire Jean, Julie* 90 297 2005 - 2010 FQRNT Établissement de nouveaux chercheurs Poste de professeur-chercheur Bazinet, Laurent* 2003 - 2008 FQRNT Établissement de nouveaux chercheurs Poste de professeur-chercheur Jean, Julie* 2003 - 2007 FQRNT Établissement de nouveaux chercheurs Poste de professeur-chercheur Saucier, Linda* 2003 - 2008 MDEIE Développement régional Initiatives de concertation régionale en Lacroix, Monique* recherche, science, technologie et innovation 176 000 2005 - 2007 MDEIE Développement régional Initiatives de concertation régionale en Lacroix, Monique* recherche, science, technologie et innovation : Transfert des connaissances vers les intervenants dans le domaine bioalimentaire dans les Laurentides 60 000 2006 - 2008 679 979 2003 - 2009 5 000 004 2002 - 2006 Chercheurs Institut IRSC Agence de Promotion Économique du Canada Atlantique Institut des nutraceutiques et des aliments fonctionnels Researcher(s) Atlantic Canada Opportunities Fund Atlantic Innovation Fund Chercheurs STELA Réseau de formation interdisciplinaire en recherche sur la santé et le vieillissement West, Gale et 76 autres chercheurs Innovations en biotechnologie médicale : développement de biothérapies via la thérapie génique et les nutraceutiques dans la prévention et le traitement de cancer Matar, Chantal* (Univ. Moncton) Farnworth, Edward Perdigon, Gabriela 1 806 274 2004 - 2011 200 000 2005 - 2006 55 000 2005 - 2006 59 970 2003 - 2007 Contracts Source of funding Name of program Entreprises privées MAPAQ : Ministère de l’Agriculture, des Pêcheries et de l’Alimentation du Québec MDEIE : Ministère du Développement économique, de l’Innovation et de l’Exportation Title of project Researcher(s) Chercheurs institut MEQ : Ministère de l’Éducation du Québec MRI : Ministère des Relations internationales du Québec NIH : National Institutes of Health (USA) PLC : Les producteurs laitiers du Canada Total amount ($) 2 000 000 Period 2005 - 2006 RCE : Réseau des centres d’excellence fédéral UPA : Union des producteurs agricoles VRQ : Valorisation Recherche Québec * Main research director 39 INAF A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 Publications Articles in peer-reviewed journals AbuMweis, S; Vanstone, C; Ebine, N; Kassis, A; Ausman, L; Jones, PJH; Lichtenstein, A (2006) Intake of a single morning dose of standard and novel plant sterol preparations for 4 weeks does not dramatically affect plasma lipid concentrations in humans, Journal of nutrition, vol. 136, p. 1012-1016 Aider, M; Arul, J; Mateescu, MA; Brunet, S; Bazinet, L (2006) Electromigration of chitosan d-glucosamine and oligomers in dilute aqueous solutions, Journal of agricultural and food chemistry, vol. 54, p. 6352-6357 Amrouche, T; Boutin, Y; Fliss, I (2006) Effects of bifidobacterial cytoplasm peptide and protein fractions on mouse lymphocyte proliferation and cytokine production, Food and agricultural immunology, vol. 17, p. 29-42 Amrouche, T; Boutin, Y; Moroni, O; Kheadr, E; Fliss, I (2006) Production and characterization of anti-bifidobacteria monoclonal antibodies and their application in the development of an imunoculture detection method, Journal of microbiological methods, vol. 65, p. 159-170 Amrouche, T; Boutin, Y; Prioult, G; Fliss, I (2006) Effects of bifidobacterial cytoplasm, cell wall and exopolysaccharide on mouse lymphocyte proliferation and cytokine production, International dairy journal, vol. 17, p. 70-80 Araya-Farias, M; Bazinet, L (2006) Effect of calcium and carbonate concentrations on anionic membrane fouling during electrodialysis, Journal of Colloids and Interface Science, vol. 296, p. 242-247 Bailey, S; Loredo-Osti, JC; Lepage, P; Faith, J; Fontaine, J; Desbiens, K; Hudson, TJ; Bouchard, C; Gaudet, D; Pérusse, L; Vohl, MC; Engert, JC (2006) Common polymorphisms in the promoter of the visfatin gene (PBEF1) influence plasma insulin levels in a French Canadian population, Diabetes, vol. 55, p. 2896-2902 Barter, PJ; Ballantyne, CM; Carmena, R; Castro Cabezas, M; Chapman, MJ; Couture, P; de Graaf, J; Durrington, PN; Faergeman, O; Frohlich, J; Furberg, CD; Gagné, C; Haffner, SM; Humphries, SE; Jungner, I; Krauss, RM; Kwiterovich, P; Marcovina, S; Packard, CJ; Pearson, TA; Reddy, KS; Rosenson, R; Sarrafzadegan, N; Sniderman, AD; Stalenhoef, AF; Stein, E; Talmud, PJ; Tonkin, AM; Walldius, G; Williams, KM (2006) Apo B versus cholesterol in estimating cardiovascular risk and in guiding therapy: report of the thirty-person/ten country panel Journal of internal medicine, vol. 259, p. 247-258 40 Bazinet, L; DeGrandpré, Y; Porter, A (2005) Electromigration of tobacco polyphenols, Separation and purification technology, vol. 41, no 1, p. 101-107 Blanchette, S; Marceau, P; Biron, S; Brochu, G; Tchernof, A (2006) Circulating progesterone and obesity in men, Hormone and metabolic research, vol. 38, p. 330-335 Bazinet, L; DeGrandpré, Y; Porter, A (2005) Enhanced tobacco polyphenol electromigration and impact on membrane integrity, Journal of membrane science, vol. 254, no 1-2, p. 111-118 Blouin, K; Blanchette, S; Richard, C; Dupont, P; Luu-The, V; Tchernof, A (2005) Expression and activity of aldoketoreductases 1C in omental adipose tissue are positive correlates of adiposity in women, American journal of physiology. Endocrinology and metabolism, vol. 888, p. E398-E404 Beaulieu, L; Aomari, H; Groleau D; Subirade, M (2006) Purification of Pediocin PA-1 Produced by Pediococcus acidilactici: Simple and scalable method for a highly purified product. Biotech Appl Biochem, 43 : 77-84 Bégin, C; Gagnon-Girouard, MP; Provencher, V; Lemieux, S (2006) Traitement de l’obésité : soutenir l’individu dans l’appropriation de sa démarche, Psychologie canadienne Bélanger, C; Hould, FS; Lebel, S; Biron, S; Brochu, G; Tchernof, A (2006) Omental and subcutaneous adipose tissue steroid levels in obese men, Steroids, vol. 71, p. 674-682 Benchaar, C; Petit, HV; Berthiaume, R; Whyte, TD; Chouinard, PY (2006) Effects of dietary addition of essential oils and monensin premix on digestion, ruminal fermentation characteristics, milk production, and milk composition in dairy cows, Journal of dairy science, vol. 89, p. 4352-4364 Bissonauth, V; Chouinard, PY; Marin, J; Leblanc, N; Richard, D; Jacques, H (2006) The effects of t10,c12 CLA isomer compared with c9,t11 CLA isomer on lipid metabolism and body composition in hamsters, Journal of nutritional biochemistry, vol. 17, p. 597-603 Blackburn, P; Després, JP; Lamarche, B; Tremblay, A; Bergeron, J; Lemieux, I; Couillard, C (2006) Postprandial variations of plasma inflammatory markers in abdominally obese men, Obesity, vol. 14, p. 1747-1754 Blanchet, C; Dodin, S (2005) Attitudes and perceptions of medical students to complementary medicine introduction to their medical curriculum: A survey, Journal of complementary and integrative medicine, vol. 2, no 1 Blanchette, S; Blouin, K; Richard, C; Dupont, P; Luu-The, V; Tchernof, A (2005) Expression and activity of 20alpha-hydroxysteroid dehydrogenase (AKR 1C1) in abdominal subcutaneous and omental adipose tissue in women, Journal of clinical endocrinology and metabolism, vol. 90, p. 264-270 Blouin, K; Després, JP; Couillard, C; Tremblay, A; Prud’homme, D; Bouchard, C; Tchernof, A (2005) Contribution of age and declining androgen levels to features of the metabolic syndrome in men, Metabolism, vol. 55, p. 1034-1040 Bolduc, MP; Bazinet, L; Lessard, J; Chapuzet, JM; Vuillemard, JC (2006) Electrochemical modification of the redox potential of pasteurized milk and its evolution during storage, Journal of agricultural and food chemistry, vol. 54, no 13, p. 4651-4657 Bolduc, MP; Raymond, Y; Fustier, P; Champagne CP; Vuillemard, JC (2006) Sensitivity of bifidobacteria to oxygen and redox potential of non-fermented pasteurized milk, International dairy journal, vol. 16, no 9, p. 1038-1048 Bossé, Y; Bouchard, L; Després, JP; Bouchard, C; Pérusse, L; Vohl, MC (2005) Haplotypes in the phospholipid transfer protein gene are associated with obesity-related phenotypes: the Quebec family study, International journal of obesity, vol. 29, no 11, p. 1338-1345 Bossé, Y; Feitosa, MF; Després, JP; Lamarche, B; Rice, T; Rao, DC; Bouchard, C; Pérusse, L; Vohl, MC (2005) Detection of a major gene effect for LDL peak particle diameter and association with apolipoprotein H haplotype, Atherosclerosis, vol. 182, no 2, p. 231-239 Bouazzaoui, K; LaPointe, G (2006) Use of antisense RNA to modulate glycosyltransferase gene expression and exopolysaccharide molecular mass in Lactobacillus rhamnosus, Journal of microbiological methods, vol. 65, p. 216-225 Bouchard, L; Mauriège, P; Vohl, MC; Bouchard, C; Pérusse, L (2005) Plasminogen activator inhibitor-1 polymorphism are associated with obesity and fat distribution in the Quebec family study: Evidence of interactions with menopause, Menopause, vol. 12, no 2, p. 136-143 A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 INAF Publications - Articles in peer-reviewed journals Boulmerka, A; Hamoudi, S; Arul, J; Belkacemi, K (2006) Hydrogenation of vegetable oils with minimum trans and saturated fatty acid formation over a nano structured Pd-catalyst. Topics in Catalysis, 37 : 113 Brisson, D; Mathieu, J; Vohl, MC; Gaudet, D (2005) Presence of palmar xanthomas in myotonic dystrophy identifies different patterns of linkage disequilibrium between the apolipoprotein E and myotonic dystrophy protein kinase loci, Genetics in medicine, vol. 7, no 3, p. 213-215 Britten, M; Lamothe, S; Robitaille, G (2006) Use of washed cream for butter making: impact on phospholipids distribution and recovery, International journal of food science and technology Caillet, S; Millette, M; Salmieri, S; Lacroix, M (2006) Combined effects of antimicrobial coating, modified atmosphere packaging and gamma irradiation on Listeria innocua present in ready to use carrots (Daucus carota), Journal of food protection, vol. 69, no 1, p. 80-85 Caillet, S; Millette, M; Turgis, M; Salmieri, S; Lacroix, M (2006) Influence of antimicrobial compounds, and modified atmosphere packaging on radiation sensitivity of Listeria innocua present in ready to use carrots (Daucus carota), Journal of food protection, vol. 69, no 1, p. 221-227 Caillet, S; Salmieri, S; Lacroix, M (2006) Evaluation of antiradical properties of grape phenol extracts by a fast colorimetric method, Journal of food chemistry, vol. 95, no 1, p. 1-18 Caillet, S; Shareck, F; Lacroix, M (2005) Effect of gamma-irradiation and oregano essential oil on murein and ATP concentration of E. coli O157:H7., Journal of food protection, vol. 68, no 12, p. 2571-2579 Cammisotto, PG; Renaud, C; Gingras, D; Delvin, E; Levy, E; Bendayan, M (2005) Endocrine and exocrine secretion of leptin by the gastric mucosa. J Histochem & Cytochem, Jul; 53(7) : 851-860. Cammisotto, P; Gingras, D; Renaud, C; Levy, E; Bendayan M (2006) Secretion of soluble leptin receptors by exocrine and endocrine cells of the gastric mucosa. Am. J. Physiol. Feb; 290(2) : G242-9 Champagne, CP; Barrette, J; Roy, D; Rodrigue, N (2006) Fresh-cheesemilk formulation fermented by a combination of freeze-dried citrate-positive cultures and exopolysaccharide-producing lactobacilli with liquid lactococcal starters, Food research international, vol. 39, p. 651-659 Chaput, JP; Drapeau, V; Hetherington, M; Lemieux, S; Provencher, V; Tremblay, A (2005) Psychobiological impact of a progressive weight loss program in obese men, Physiology & behavior, vol. 86, p. 224-232 Charbonneau, E; Chouinard, PY; Allard, G; Lapierre, H; Pellerin, D (2006) Milk from Forage as Affected by Rumen Carbohydrate Degradability when Feeding Alfalfa Silage-Based Diets, Journal of dairy science, vol. 89, p. 283-293 Charles, MT; Kalantari, S; Corcuff, R; Arul, J (2005) Post-harvest quality and sensory evaluation of UV-treated tomato fruit, Acta Horticulturae, vol. 682, p. 537-542 Charles, MT; Mercier, J; Makhlouf, J; Arul, J (2006) Induction of resistance to gray mold and accumulation of the phytoalexin rishitin in postharvest tomato fruit by UV treatment, Postharvest biology and technology Chemak, F; Romain, R; West, G. (2006) Effet du statut foncier sur les systèmes de production et sur les revenus des familles de la communauté de Zoghmar dans le semi-aride tunisien. Canadian Journal of Development Studies, 27(3) : 365-381. Chen, L; Remondetto, GE; Subirade, M (2006) Food protein-based materials as nutraceutical delivery systems, Trends in food science & technology, vol. 17, p. 272-283 Chen, L; Subirade, M (2006) Novel alginate whey protein matrix-granule microspheres as oral delivery vehicles for bioactive compounds, Biomaterials, vol. 27, p. 4646-4654 Chiasson, F; Borsa, J; Lacroix, M (2005) Combined effect of carvacrol and packaging conditions on Escherichia coli and Salmonella Typhi radiosensitivity in ground beef, Journal of food protection, vol. 68, no 12, p. 2567-2570 Christon, R; Drouin, O; Marette, A (2005) Redox modulation of insulin signaling and endothelial function, Antioxidants & redox signaling, vol. 7, p. 1062-1079 Christon, R; Marette, A; Badeau, M; Bourgoin, F; Mélançon, S; Bachelard, H (2005) Fatty acid-induced changes in vascular reactivity in healthy adult rats, Metabolism, vol. 54, no 12, p. 1600-1609 Ciesla, K; Salmieri, S; Lacroix, M (2006) Modification of the milk proteins films properties by gamma irradiation and polysaccharides addition, Journal of the science of food and agriculture, vol. 86, no 6, p. 908-914 Ciesla, K; Salmieri, S; Lacroix, M (2006) y-Irradiation influence on the structure and properties of Calcium caseinate-whey protein isolate based films. Part I. Radiation effect on the structure of proteins gels and films, Journal of agricultural and food chemistry, vol. 54, p. 6374-6384 Ciubotariu, I; Levy, E; Haddad, PS (2006) The effects of calcium antagonists on lipid synthesis and secretion in HTC cells. Biologie & Santé 6(1) : 1-12. Couillard, C; Pomerleau, S; Archer, WR; Ruel, G; Bergeron, J; Couture, P; Lamarche, B; Bergeron, N (2006) Associations between dietary fat intake, LDL oxidation and endothelial activation in men, Nutrition, vol. 22, p. 600-608 Couillard, C; Ruel, G; Archer, WR; Pomerleau, S; Bergeron, J; Couture, P; Lamarche, B; Bergeron, N (2005) Circulating levels of oxidized LDL and endothelial adhesion molecules in men with abdominal obesity, Journal of clinical endocrinology and metabolism, vol. 90, p. 6454-6459 Cunnane, SC (2006) L’évolution du cerveau humain : de la matière grasse à la matière grise, Médecine sciences, vol. 22, p. 659-663 Cunnane, SC; Ryan, MA; Lin, YH; Lim, SY; Salem, N (2006) Deficiency of omega-3 polyunsaturates does not diminish carbon recycling of α-linolenic acid, Pediatric research, vol. 59, p. 107-110 Dabour, N; Kheadr, EE; Benhamou, N; Fliss, I; LaPointe, G (2006) Improvement of texture and structure of reduced-fat Cheddar cheese by exopolysaccharide-producing Lactococci, Journal of dairy science, vol. 89, p. 95-110 Dabour, N; LaPointe, G; Fliss, I; Benhamou, N; Kheadr, EE (2005) Application of ruthenium red and colloidal gold-labeled lectin for the visualisation of bacterial exopolysaccharides in Cheddar cheese matrix using transmission electron microscopy, International dairy journal, vol. 15, no 10, p. 1044-1055 Delvin, EE; Salle, BL; Claris, O; Putet, G; Hascoët, JM; Desnoulez, L; Messai, S; Levy, E. (2005) Oral vitamin A, E and D supplementation of pre-term newborns either breast-fed or formula-fed: A 3-month longitudinal study. J. Pediatr. Gastroenterol. Nutr. 40 : 43-47. Demmers, T; Jones, PJH; Wang, Y; Krug, S; Creutzinger, V; Heubi, JE (2005) Effects of early cholesterol intake on cholesterol biosynthesis and plasma lipids in infants until 18 months of age, Pediatrics, vol. 115, p. 1594-1601 Denoncourt, P; Amyot, A; Lacroix, M (2006) Evaluation of two biodegradable coatings on corn quality, Journal of the science of food and agriculture, vol. 86, p. 392-400 Désilets, MC; Garrel, D; Couillard, C; Tremblay, A; Després, JP; Bouchard, C; Delisle, H (2006) Ethnic differences in body composition and other markers of cardiovascular disease risk: Study in matched Haitian and White subjects from Québec, Obesity, vol. 14, p. 1019-1027 Desmarteau, R; Saives, AL (2006) Les très petites entreprises de biotechnologie sont-elles contre-nature ? Découvrir leur identité au Québec (Canada) en explorant leur modèle d’affaires, Revue Internationale PME, vol. 19, no 1, p. 35-68 Desroches, S; Archer, WR; Paradis, ME; Deriaz, O; Couture, P; Bergeron, J; Bergeron, N; Lamarche, B (2006) Baseline plasma C-reactive protein concentrations influence lipid and lipoprotein responses to low-fat and high monounsaturated fatty acid diets in healthy men, Journal of nutrition, vol. 136, p. 1005-1011 41 INAF A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 Publications - Articles in peer-reviewed journals Desroches, S; Chouinard, PY; Galibois, I; Corneau, L; Delisle, J; Lamarche, B; Couture, P; Bergeron, N (2005) Lack of effect of dietary conjugated linoleic acids naturally incorporated into butter on the lipid profile and body composition of overweight and obese men, American journal of clinical nutrition, vol. 82, p. 309-319 Destaillats, F; Angers, P (2005) On the Mechanisms of Cyclic and Bicyclic Fatty Acid Monomer Formation in Heated Edible Oils, European journal of lipid science and technology, vol. 107, p. 767-772 Dubois, MJ; Bergeron, S; Kim, HJ; Dombrowski, L; Perreault, M; Fournès, B; Faure, R; Olivier, M; Beauchemin, N; Shulman, GI; Siminovitch, KA; Kim, JK; Marette, A (2006) The SHP-1 protein tyrosine phosphatase negatively modulates glucose homeostasis, Nature medicine, vol. 12, no 5, p. 549-556 Ebine, N; Demonty, I; Jia, X; Jones, PJH (2006) Plant stanol ascorbate esters reduce body weight gain through decreased energy absorption in hamsters, International journal of obesity, vol. 30, p. 751-757 Destaillats, F; Sébédio, JL; Berdeaux, O; Juaneda, P; Angers, P (2005) Gas Chromatography-Mass Spectrometry Determination of Metabolites of Conjugated cis-9,trans-11,cis-15 18:3 Fatty Acid, Journal of chromatography B, vol. 820, p. 15-22 Emmerich, J; Vossen, CY; Callas, PW; Demers, C; Naud, S; Long, GL; Couture, P; Rosendaal, FR; Bovill, EG (2005) Chronic venous abnormalities in symptomatic and asymptomatic protein C deficiency, Journal of thrombosis and hæmostasis, vol. 3, p. 1428-1431 Destaillats, F; Trottier, JP; Garro Galvez, JM; Angers, P (2005) Analysis of α-Linolenic acid biohydrogenation intermediates in milk fat with emphasis on conjugated linolenic acids, Journal of dairy science, vol. 88, p. 3231-3239 Fallon, E; Tremblay, N; Desjardins, Y (2006) Changes in Yield, Size Distribution and Grain Moisture Content in Peas (Pisum sativum L.) Grown for Processing., Canadian journal of plant science, vol. 86, p. 525-537 Di-Marco, S; Mazroui, R; Dallaire, P; Chittur, S; Tennebaum, S; Radzioch, D; Marette, A; Gallouzi, IE (2005) NF-kB-mediated MyoD decay during muscle wasting requires iNOS mRNA stabilization, HuR protein and nitric oxide release, Molecular and cellular biology, vol. 25, no 15, p. 6533-6545 Faucitano, L; Saucier, L; Correa, JA; Méthot, S; Giguère, A; Foury, A; Mormède, P; Bergeron, R (2006) Effect of feed texture, meal frequency and pre-slaughter fasting on carcass and meat quality, and urinary cortisol in pigs, Meat science, vol. 74, p. 697-703 Dodin, S Arthrose du genou et glucosamine (Toujours pas de réponse claire !). L’Actualité médicale, mai 2006, 27(17) : 38. Dodin, S (2006) Acupuncture et soulagement de la douleur lombaire chronique (une revue systématique). L’Actualité médicale, février 27(4) : 30. Dodin, S Les omega-3 sont-ils aussi efficaces que les statines pour réduire la mortalité globale et la mortalité cardiovasculaire ? L’Actualité médicale, octobre 2005, 26(34) : 38. Doepel, L; Lessard, M; Gagnon, N; Lobley, GE; Bernier, JF; Dubreuil, P; Lapierre, H (2006) Effect of Glutamine Supplementation on Immune Response and Milk Production in Dairy Cows, Journal of dairy science, vol. 89, p. 3107-3121 D’Souza, DH; Sair, A; Williams, K; Papafragkou, E; Jean, J; Moore, C; Jaykus, LA (2006) Persistence of caliciviruses on environmental surfaces and their transfer to food, International journal of food microbiology, vol. 108, p. 84-91 Dubé, MC; Joanisse, DR; Prud’homme, D; Lemieux, S; Bouchard, C; Pérusse, L; Lavoie, C; Weisnagel, SJ (2006) Muscle adiposity and body fat distribution in type 1 and type 2 diabetes: varying relationships according to diabetes type, International journal of obesity, vol. 30, p. 1721-1728 42 Faye, L; Boulaflous, A; Benchabane, M; Gomord, V; Michaud, D (2005) Protein modifications in the plant secretory pathway: current status and practical implications for plant molecular farming, Vaccine, vol. 23, p. 1770-1778 Gagnon, M; Kheadr, E; Le Blay, G; Fliss, I (2006) In effect of Bifidobacterium thermacidophilum probiotic feeding on enterohemorrhagic Escherichia coli O157: H7, International journal of food microbiology, vol. 111, p. 26-33 Garenc, C; Couillard, C; Laflamme, N; Cadelis, F; Gagné, C; Couture, P; Julien, P; Bergeron, J (2005) Effect of the APOC3 SstI SNP on fasting triglyceride levels in men heterozygous for the LPL P207L deficiency, European journal of human genetics, vol. 13, p. 1159-1165 Gaudreau, H; Fliss, I; Champagne, CP (2006) Stability of autolytic lactococci during starter production and storage in commercial whey-based media. International Dairy Journal, 16(1) pp. 200-206. Gauthier, SF; Pouliot, Y; Maubois, JL (2006) Growth factors from bovine milk and colostrum: composition, extraction and biological activity, Le Lait, vol. 86, no 2, p. 99-125 Gauthier, SF; Pouliot, Y; St-Sauveur, D (2006) Immunomodulatory peptides obtained by the enzymatic hydrolysis of whey proteins, International dairy journal, vol. 16, no 11, p. 1315-1323 Gervais, R; Spratt, R; Léonard, M; Chouinard, PY (2005) Lactation response of cows to different levels of ruminally inert conjugated linoleic acids under commercial conditions, Canadian journal of animal science, vol. 85, p. 231-242 Goulet, J; Lapointe, A; Lemieux, S; Lamarche, B (2006) Mediterranean diet and cardiovascular disease, Current nutrition and food science, vol. 2, p. 265-274 Goulet, C; Ward, L; Levy, E; Colin, C (2006) La recherche infirmière en milieu clinique : l’expérience du CHU Mère-Enfant. [Clinical nursing research: academic medical center of maternal-child hospital St. Justine] Rech. Soins Infirm. Mar (84): 84-90. Guillaume, N; Morency, H; LaPointe, G; Lavoie, MC (2006) Mutacin H-29B is identical to mutacin II (J-T8), BMC Microbiology journal, vol. 6, no 36 Haddad, PS; Beauchamp, G; Côté, G; Boivin, M (2005) Maintenance of an efficient and equilibrated immune system through the novel use of natural health products: Synopsis of a Symposium. Evid. Based Complement. Altern. Med. 2 : 237-238. Haddad, PS; Azar, G; Groom, S; Boivin, M (2005) Natural health products, modulation of immune function, and prevention of chronic diseases. Evid. Based Complement. Altern. Med. Dec; 2 : 513-520. 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Tchernof, A; Bélanger, C; Morisset, AS; Richard, C; Mailloux, J; Laberge, P; Dupont, P (2006) Regional differences in adipose tissue metabolism in women: Minor effect of obesity and body fat distribution, Diabetes, vol. 55, p. 1353-1360 Thériault, M; Caillet, S; Kermasha, S; Lacroix, M (2006) Antioxidant, antiradical and antimutagenic activities of phenolic compounds present in maple products, Food chemistry, vol. 98, p. 490-501 Toth, MJ; Ades, PA; LeWinter, MM; Tracy, RP; Tchernof, A (2005) Skeletal muscle myofibrillar mRNA levels in heart failure: relationship to local and circulating growth factors and cytokines, Journal of applied physiology, vol. 100, p. 35-41 Tremblay, AJ; Lamarche, B; Cohn, JS; Hogue, JC; Couture, P (2006) Effect of ezetimibe on the in vivo kinetics of apoB-48 and apoB-100 in men with primary hypercholesterolemia, Arteriosclerosis, thrombosis, and vascular biology, vol. 26, p. 1101-1106 Tremblay, AJ; Lamarche, B; Ruel, IL; Hogue, JC; Deshaies, Y; Gagné, C; Couture, P (2006) Effects of fenofibrate on apolipoprotein kinetics in patients with coexisting dysbetalipoproteinemia and heterozygous familial hypercholesterolemia, Atherosclerosis, vol. 188, p. 203-212 Tremblay, F; Gagnon, AM; Veuilleux, A; Soriski, A; Marette, A (2005) Activation of the mTOR pathway acutely inhibits insulin-induced glucose transport by decreasing PI(3,4,5)P3 production and Akt activity in 3T3-L1 adipocytes, Endocrinology, vol. 146, no 3, p. 1328-1337 Tremblay, F; Krebs, M; Dombrowski, L; Brehm, A; Bernroider, E; Roth, E; Nowotny, P; Waldhausl, W; Marette, A; Roden, M (2005) Overactivation of S6K1 as a cause of human insulin resistance during increased amino acid availability, Diabetes, vol. 54, no 9, p. 2674-2684 Varady, KA; Jones, PJH (2005) Combination diet and exercise interventions for the treatment of dyslipidemia: an effective preliminary strategy to lower cholesterol levels?, Journal of nutrition, vol. 135, p. 1829-1835 Vogt, JA; Ishii-Schrade, KB; Pencharz, PB; Jones, PJH; Wolever, TMS (2006) L-rhamnose and lactulose decrease serum triacylglycerols and their rates of synthesis, but do not affect serum cholesterol concentrations in humans, Journal of nutrition, vol. 136, p. 2160-2166 Vohl, MC; Houde, A; Lebel, S; Hould, FS; Marceau, P (2005) Effects of the peroxisome proliferator-activated receptor-gamma coactivator-1 Gly482Ser variant on features of the metabolic syndrome, Molecular genetics and metabolism, vol. 86, no 1-2, p. 300-306 Wang, Y; Jones, PJH; Woollett, LA; Buckley, DD; Yao, L; Granholm, NA; Tolley, EA; Heubi, JE (2006) Effects of chenodeoxycholic acid and deoxycholic acid on cholesterol absorption and metabolism in humans, Translational research, vol. 147, p. 37-45 West, GE; Larue, B (2005) Determinants of anti-GM food activism, Journal of public affairs, vol. 5, p. 236-250 White, PJ; Marette, A (2006) Is omega-3 key to unlocking inflammation in obesity?, Diabetologia, vol. 49, no 9, p. 1999-2001 Woollett, LA; Wang, Y; Buckley, DD; Yao, L; Chin, S; Granholm, N; Jones, PJH; Setchell, KDR; Tso, P; Heubi, JE (2006) Micellar solubilisation of cholesterol is essential for absorption in humans, Gut, vol. 55, p. 197-204 Yaganza, ES; Tweddell, RJ; et Arul, J (2005) Effect of pre-storage application of selected organic and inorganic salts on stored potato quality. 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Yoshida, M; Vanstone, CA; Parsons, WD; Zawistowski, J; Jones, PJH (2006) Effect of plant sterols and glucomannan on lipids in individuals with and without type II diabetes, European journal of clinical nutrition, vol. 60, p. 529-537 45 INAF A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 Publications Contributions to collective works Benchabane, M; Michaud, D (2006) Hybrid, multifunctional proteins useful in plant pest control, Taxeira da Silva JA, vol. 4, Floriculture, Ornemental and Plant Biotechnology: Advances and Topical Issues, Global Science Books, Tokyo (Japon), p. 171-175 Caballos-Picot, I; Blum, D; Ramassamy, C; Przedborski, S (2005) Stress oxydatif dans les processus neurodégénératifs et la mort neuronale : cause ou conséquence ?, Radicaux libres et stress oxydant., Jacques Delattres, Jean-Louis Beaudeux, Dominique Bonnefont-Rousselot, Lavoisier, p. 429-474 Goulet, C; Michaud, D (2006) Degradation and stabilization of recombinant proteins in plants, Taxeira da Silva JA, vol. 4, Floriculture, Ornemental and Plant Biotechnology: Advances and Topical Issues, Global Science Books, Tokyo (Japon), p. 35-40 Jones, PJH; Kubow, S (2006) Lipids, sterols and their metabolites, Modern Nutrition in Health and Disease, 10th Edition, M.E. Shils, M. Shike, A.C. Ross, B. Caballero, R.J. Cousins. Lippincott Williams and Wilkins. Lacroix, M (2005) The use of irradiation to assure food safety, Emerging Technologies for Food Processing, Da-Wen Sun, ed., Academic Press, Elsevier, London, p. 353-389 46 Lacroix, M; Le Tien, C (2005) Edibles films and coating from non-starch polysaccharides, Innovation in food packaging, J.H. Han, ed., Elsevier, Academic Press, UK, p. 338 Ratti, C; Mujumdar, AS (2006) Infrared drying, Handbook of industrial drying, vol. 1, A. S. Mujumdar, Marcel Dekker Saucier, L; Champagne, CP (2005) Cell immobilization technology and meat processing, Applications of cell immobilisation biotechnology, vol. 8B, Nedonic, V., Willaert, R., Springer, London, UK. Tchernof, A (2005) Le syndrome polymétabolique chez la femme, Nutritions et facteurs de risque, vol. 3, no 19, p. 265-280 Tchernof, A; Després, JP (2005) Obesity and dyslipidemia: importance of body fat distribution, Clinical Obesity and related metabolic disease in adults and children, second edition., Ed. P. Kopelman, I. Caterson, W. Dietz. Blackwell Science, p. 163-183 Varady, KA; Jones, PJH (2006) Lipid sources and plant sterols: Effect of food and food-drug Synergy on Cardiovascular Disease Risk, Food-Drug Synergy and Safety, L.U. Thompson, W.E. Ward. Taylor and Francis Group Books Belkacemi, K; Hamoudi, S; Arul, J (2005) Hydrogenation of vegetable oils : Overview of recent developments in catalysis and reaction engineering aspects. Research SignPost. 3: 43-65 Cunnane, SC (2005) Survival of the fattest: The key to human brain evolution, World Scientific Publishing Co., River Edge, NJ, USA Haddad, PS; Martineau, L; Lyoussi, B; Le, PM (2006) Middle eastern and african medicine. Traditional herbal medicines for modern times: Antidiabetic plants (A. Soumyanath, ed.), CRC Press, pp. 221-241 A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 INAF Communications by INAF members Aider, M., Bazinet, L., Arul, J., Brunet, S. and Mateescu, M-A. Étude du comportement électrophorétique des oligomères de chitosane. 2e Symposium de l’INAF, Québec, Canada, October 6-7, 2005. Akbache, A., Lamiot, É., Pouliot, Y., Gauthier, S.F., Turgeon, S.L. Effet du procédé fromager sur la teneur en facteurs de croissance dans les lactosérums et les isolats de protéines produits par ultrafiltration. Colloque étudiant de l’INAF, CRCHUL, Québec, 5 juin 2006. Akbache, A., Lamiot, E., Pouliot, Y., Effet du procédé fromager sur les caractéristiques d’isolats de protéines de lactosérum obtenus par ultrafiltration. 2e Symposium de l’INAF, Québec, 6-7 octobre 2005. Ayala-Bribiesca, E., Pourcelly, G., Bazinet, L. Effect of pH on Membrane Fouling by Minerals and Proteins during Conventional Electrodialysis. Proceeding du « International Congress on Membranes and Membrane Processes (ICOM 2005) », Séoul (Corée du Sud), 21-25 Août 2005, Section Membrane Fouling and Characterization, Volume II, PW 233, pp.1263-1264. Ayala-Bribiesca, E., Pourcelly, G., Bazinet, L. Effet du pH sur le colmatage des membranes par les minéraux et les protéines en cours d’électrodialyse conventionnelle. Poster présenté au 2ème symposium de l’INAF, organisé en collaboration avec le CQVB « Aliments fonctionnels et produits nutraceutiques : États et connaissances », Québec (Qc), 6-7 Octobre 2005. Al-Akoum, M., Maunsell, E., Verreault, R., Otis, H., Provencher, L., Dodin, S. Efficacité du millepertuis versus placebo sur les symptômes de ménopause chez les femmes ménopausées : une étude pilote. 8e Journée annuelle de la recherche de la Faculté de médecine de l’Université Laval, Québec, 31 mai 2006. Ayala-Bribiesca, E. ; Pourcelly, G. ; Bazinet, L. Colmatage de membranes échangeuses d’ions par les minéraux et les protéines en cours d’électrodialyse conventionnelle. Poster présenté au MEMPRO 3 Intégration des membranes dans les procédés, Nancy (France), 5-7 avril 2006. Allard, G., G. Bélanger, R. Drapeau, R. Michaud, G. Tremblay, P.Y. Chouinard, D. Pellerin, P. Séguin, D. Lefebvre et A. Fournier. Production de fourrages adaptés aux besoins de la vache tarie. Forum technologique Novalait 2006 « Miser sur l’innovation pour agir face au changements », 30 mai, Bécancour, QC. Cahier du Forum technologique Novalait 2006, Novalait inc., Québec, QC, fiche P2006-05. Batungwanayo, A., Araya, M. and Ratti, C. "Freeze-drying of garlic (A.sativum) and its effect on allicin retention". IADC 2005 (Inter-American Drying Conference), August 21-23, 2005, Montreal, Canada. Allard, G., D. Pellerin, G. Bélanger, H. Brassard, A. Brégard, *É. Charbonneau, P.Y., Chouinard, R. Drapeau, A. Fournier, D. Lefebvre, R. Michaud, S. Pelletier, P. Seguin et G. Tremblay. 2005. (Conférence sur invitation) Foins pour vaches taries, une solution québécoise ! Symposium sur les bovins laitiers, Saint-Hyacinthe, 25 octobre 2005. Angers, P., and Destaillats, F. On the Mechanisms of Cyclic and Bicyclic Fatty Acid Monomer Formation in Heated Oils. 26th World Congress and Exhibition of the ISF, September 2005, Prague, Czech Republic. Angers, P., Arul, J., Ngo-Duy, C.C., Belkacemi, K., and Chouinard, P.Y., Structural Triglyceride Analysis of Milk Fat Enriched in Conjugated Linoleic Acid and of Regular Milk Fat. 26th World Congress and Exhibition of the ISF, September 2005, Prague, Czech Republic. Arul, J. Ozone 101. Atelier sur l’ozone en agriculture. IRDA, Québec, 7 avril, 2006. Arul, J., Corcuff, R., Constantin, A., Angers, P. and Makhlouf, J. Relation structure-fonction dans la capacité antioxydante de onze cultivars de canneberges. 2e Symposium de l’INAF, Québec, Canada, 6-7 octobre, 2005. Bazinet, L., Araya-Farias, M. Effect of calcium and carbonate concentrations on Cationic membrane fouling during electrodialysis. Proceeding du « International Congress on Membranes and Membrane Processes (ICOM 2005) », Séoul (Corée du Sud), 21-25 Août 2005, Section Membrane Fouling and Characterization, Volume II, PW 248, pp. 1293-1294. Bazinet, L. Obtention de molécules nutraceutiques par procédés électro-membranaires. Conférencier invité au 2ème symposium de l’INAF, organisé en collaboration avec le CQVB « Aliments fonctionnels et produits nutraceutiques : États et connaissances », Québec (Qc), 6-7 Octobre 2005. Bazinet, L. Revue des principales réactions affectant la dégradation des aliments, et démystification des équations complexes permettant d’en évaluer les effets. Conférencier invité, au séminaire « Durée de vie des produits alimentaires : applications pratiques », Saint-Hyacinthe (Qc), 17 Novembre 2005. Bazinet, L. Séparation des protéines sériques par électroacidification avec membranes bipolaires. Conférencier invité, MEMPRO 3 « Intégration des membranes dans les procédés », Nancy (France) 5-7 avril 2006. Belkacemi, K. et S. Hamoudi. Phenomenological Kinetics of Wet Air Oxidation: Operating Severity Facto rand Recalcitrance Index, Chemical Reactor Engineering X: Innovations in Chemical Reactor Engineering, Zacatecas City, Zacatecas, Mexico, 28 septembre au 2 août 2005. Benabbou, R., Zihler, A. and Fliss, I. Antimicrobial activity of chitosan and divergicin M35 and their combination against Listeria monocytogenes. Conférence conjointe ICSTA/AAC 2006, Montréal du 28 au 30 mai. Benabbou, R., Zihler, A. et Fliss, I. Development of bio-active film of chitosan and divergicin M35 to control growth of Listeria monocytogenes in food samples. 1st International symposium on food, veterinary and medical applications of antimicrobial peptides. ENITIAA, Nantes, France, 21-23 juin 2006. Benhaddou-Andaloussi, A, Martineau, LC, Spoor, D., Leduc, C., Prentki, M., Settaf, A, Baddouri, K, Haddad, PS. (2005) L’effet anti-diabétique de Nigella Sativa chez les cellules du muscle squelettique et les adipocytes. IXe congrès scientifique Annuel de Bio-Alliance Canada-Maroc, 11 juin 2005, Montréal. Benhaddou-Andaloussi, A., Martineau, L., Spoor, D., Leduc, C., Settaf, A., Baddouri, K., Haddad, PS. (2005). Anti-diabetic effects of Nigella sativa extract in skeletal muscle cells and adipocytes. International Symposium on Human Health Effects of Fruits and Vegetables. Québec, August 17-20, p. 66. Benhaddou-Andaloussi, A., Martineau, LC., Spoor, D., Leduc, C., Meddah, B., Settaf, A., Baddouri, K., Haddad, PS. (2006). The antidiabetic action of Nigella sativa is mediated by insulin-sensitizing activity in muscle cells and adipocytes. North American Research Conference on Complementary and Integrative Medicine. May 24-27 2006, Edmonton, Canada. Benchabane, M., Gomord, V., Faye, L. et Michaud, D. Recombinant forms of a human serpin expressed BY-2 tobacco cultured cells. Biotechnology Havana, La Havane (Cuba), 27 novembre-2 décembre 2005. Bendayan, M, Cammisotto, PG, Renaud, C, Gingras, D, Delvin, E, Levy, E. Sécrétion endocrine et exocrine de la leptine par la muqueuse gastrique. 3e colloque du réseau mère-enfant de la Francophonie, 9-10 juin 2005, Genève. Bolduc, M-P., Vuillemard, J-C., Champagne C., Bazinet, L. Electrochemical modification of milk and its effect on the native microflora. Proceeding du « International Congress on Membranes and Membrane Processes (ICOM 2005) », Séoul (Corée du Sud), 21-25 Août 2005, Section Novel Applications, PW 321, pp. 1425-1426. 47 INAF A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 Communications by INAF members Bolduc, M.P., Raymond Y., Fustier P., Champagne, C. et Vuillemard, J.C. Sensibilité des bifidobactéries à l’oxygène et aux potentiel d’oxydoréduction dans le lait pasteurisé. 2e Symposium de l’INAF. Aliments fonctionnels et produits nutraceutiques : états et connaissances, Sainte-Foy, 6-7 octobre 2005. Bolduc, M.P., Vuillemard, J.-C., Champagne, C. et Bazinet, L. 2006. Electrochemical modification of milk and its effect on the native microflora. International Congress on Bioprocesses in Food Industries, Patras, Grèce, 18-20 juin 2006. Bolduc, M.P., Vuillemard, J.-C., Champagne, C. et Bazinet, L. 2006. Effet de la modification électrochimique du lait sur sa microflore native. MemPro3 : intégration des membranes dans les procédés. Nancy, France, 5-7 avril 2006. Bolduc, M.P., Vuillemard, J.-C., Champagne, C. et Bazinet, L. 2005. Sensitivity of bifidobacteria to oxygen and redox state of non-fermented pasteurized milk. 4th NIZO Dairy Conference: Prospects for Health, Well-Being and Safety. Papendal, The Netherlands, 15-17 juin 2005. Borsa, J. and Lacroix, M. Advances in improving the efficacy of irradiation for killing food-borne pathogens. Institute of Food Technology (IFT) meeting. New Orleans 16-20 juillet 2005. Borsa, J. and Lacroix, M. Radiosensitization of food-borne pathogens as a means of increasing the efficacy of irradiation for decontaminating foods. International Meeting of Irradiation Processing (IMRP). Kuala Lumpur, 26 février au 3 mars 2006. Boulmerka, A., Arul, J. and Belkacemi, K. Hydrogenation of sunflower and canola oils with novel Pd-catalysts supported on structured silica, 26th World Congress of the ISF, Prague, Czech Republic, September 25-28, 2005. Boulmerka, A., S. Hamoudi, Arul, J. et Belkacemi, K. Novel structured Pd-catalysts: Recent developments in vegetable oil hydrogenation. Chemical Reactor Engineering X: Innovations in Chemical Reactor Engineering, Zacatecas City, Zacatecas, Mexico, 28 septembre – 2 août 2005. Brisson, G.*, Britten, M., Pouliot, Y. Separation of lactoferrin from cheese whey by electrofiltration. (Conférence sur invitation) Sommet mondial laitier de la FIL, Vancouver, 20 septembre 2005. * Gagnant d’un prix étudiant Brisson, G., Britten, M., Pouliot, Y. Electricallyenhanced membrane separation of lactoferrin from a whey protein isolate. North American Membrane Society (NAMS) Annual Meeting, Chicago, 14-18 mai 2006. Britten, M.; Angers, P. ; Bazinet, L. ; Champagne, C.; Chapuzet, J.-M. ; Fustier, P. ; Lessard, J. ; Pouliot, Y. ; Vuillemard, J.-C. Régulation électrochimique du potentiel d’oxydoréduction du lait : impact sur l’efficacité de transformation et la qualité des produits. Fiche Trans-Info, Forum Technologique Novalait « Miser sur l’Innovation pour agir face aux changements ». Bécancour (Qc), 30 mai 2006. 48 Britten, M. 2006. Milk and Dairy processing. Canadian Dairy Commission, Ottawa, April 21. Britten, M. 2005. Phénomènes de séparation de phases lors de l’entreposage des produits liquides. Atelier : Vie utile des produits alimentaires. La Fondation des Gouverneurs, St-Hyacinthe (Qc.), 17 novembre. Britten, M. 2005 Technologies pour le développement d’aliments fonctionnels. Deuxième symposium de l’institut sur les nutraceutiques et aliments fonctionnels en collaboration avec le CQVB. Québec (Qc), 6-7 octobre. Britten, M. and Paquin, P. 2005 Effect of reducing protein concentration on the properties of dairy creams. International Dairy Federation World Dairy Summit, Vancouver (BC), September 19-22. Bui, T., Makhlouf, J. et Ratti, C. Characterization of locally grown Savoura tomatoes at different maturity stages. 2005. FAV Fruits and Vegetables Effects on Health International Symposium. Août, Québec. Cammisotto, PG, Gingras, D, Renaud, C, Levy, E, Bendayan, M. Sécrétion simultanée de la leptine associée à son récepteur par la muqueuse gastrique. 4e Symposium de physiopathologie du tube digestif, 17 juin 2005, Orford, Québec. Casademont, C., Araya-Farias, M., Pourcelly, G., Bazinet, L. Effect of Mg/Ca ratio in treated solutions on membrane fouling during electrodialysis. Poster présenté lors de la 3e édition de la Conférence sur la Recherche et l’innovation Québécoise en Agriculture et en Agroalimentaire. Québec. 21-22 mars 2006. Casapsiuc, N., Belkacemi, K., Arul, J. and Angers, P. Formation Kinetics of Cyclic Fatty Acid Monomers of Linolenic Acid. 97th AOCS Annual Meeting, St-Louis, MO, April 30-May 3, 2006. Champagne, A., Dion, P., LaPointe, G., Antoun, H., Drouin, P. et Lafrenière, C. Inhibition of Clostridium tyrobutyricum by bacteriocin–like inhibitory substances (BLIS) produced by forage grass bacteria. CSM Annual Meeting,Halifax, Nouvelle-Écosse. Juin 2005. Champagne, A., Dion, P., Drouin, P., LaPointe, G., Antoun, H. et Lafrenière, C. Substances inhibitrices influençant le développement des spores butyriques dans l’ensilage. Forum Technologique Novalait, Bécancour, QC, mai 2006. Chay Pak Ting, B.P., Gauthier, S.F., Pouliot, Y. Fractionnement d’un mélange peptidique issu d’un hydrolysat trypsique de ß-lactoglobulin par une membrane de nanofiltration spiralée. Colloque étudiant de l’INAF, CRCHUL, Québec, 5 juin 2006. Chay Pak Ting, B., Pouliot, Y., Gauthier, S.F., Morin, P. Fractionation of ß-lactoglobulin tryptic peptides using spiral wound NF membranes. North American Membrane Society (NAMS) Annual Meeting, Chicago, 14-18 mai 2006. Chen, L., Subirade, M. Chitosan nanoparticles as oral delivery vehicles for nutraceutical compounds Symposium on Medecine from the sea, Rimouski, Canada, 15-17 août 2005. Chen, L., Subirade, M. Novel Alginate-Whey protein granular microspheres as oral delivery vehicles for bioactive compounds. CIFST/AAFC Joint Conference. Montreal, p. 28-30, mai 2006. Chen, L, Subirade, M. Preparation of alginate-whey protein microspheres by emulsification /internal gelation and their applications in healthy food. Conference on Bioencapsulation, Kingston, pp. 61-62, 24-26 juin 2005. Chouinard, P.Y. 2005. Production de viande enrichie en acides gras oméga-3 et en acides linoléiques conjugués. Présentée au Congrès du bœuf 2005 : Mettre en marché autrement. 7 octobre. Parc de l’exposition, Victoriaville. Chouinard P.Y. 2005. Utilisations des acides gras oméga-3 en production laitière et bovine. Présenté dans le cadre de la rencontre technologique intitulée : Additifs et suppléments alimentaires en production animale : innovations et tendances. Réseau Zoo-Innovation, Centre québécois de valorisation des biotechnologies, 7 juin, Saint-Hyacinthe, QC. Chouinard, P.Y. 2005. (Conférencier invité) L’intérêt des acides linoléniques conjugués au Canada. Rencontre d’information organisée par la compagnie Xéris. Université Bretagne Sud, Vannes, France. Corcuff, R., Gardner, M., Desjardins, Y., Makhlouf, J. and Arul, J. Caractéristiques physico-chimiques et nutraceutiques de cultivars de canneberges pour les conditions climatiques du Québec. 2e Symposium de l’INAF, Québec, Canada, october 6-7, 2005. Couillard, C. Postprandial fat metabolism, sex differences and risk of type 2 diabetes. Agri-Food Innovation Forum. Toronto (Canada) June 19-21, 2005. Couillard, C. Potential role of cranberries in CVD prevention: Clinical observations in humans. 1st International Symposium on the Effects of Fruits and Vegetables on Human Health. Sponsored by the International Society of Horticulture Sciences, Québec (Canada) August 17-20, 2005. Couillard, C. Results of a clinical study on the effects of cranberry juice on cardiovascular disease. Seminar on Health Effects of Cranberries (Canada) August 19, 2005 Couillard, C. La canneberge et la santé cardiovasculaire. 2nd Annual INAF Symposium. Sponsored by the Centre québécois de valorisation des biotechnologies, Québec (Canada) October 7, 2005. Cunnane, S. Metabolic constraints on human brain evolution. University of Alberta, October 2005. Cunnane, S. Nutritional constraints on human brain evolution. Colloquium at Laval University, March 2005. Cunnane, S. Lipid metabolism and brain function during aging. Fatty Acids in Cell Signalling Conference, Paris, Sept 2005. Cunnane, S. Metabolism of polyunsaturates during aging. DHA Symposium, Congress on Cellular and Molecular Biology, Poitier, France, Oct 2005. A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 INAF Communications by INAF members Dabour, N, Kheadr, E., Benhamou, N, Fliss, I. et LaPointe, G. Contribution of exopolysaccharideproducing Lactococcus lactis subsp. cremoris to microstructure and textural changes in low-fat Cheddar cheese during ripening. 8e International Symposium on Lactic Acid Bacteria, The Netherlands. Août. 2005. Dachet, F., Labrie, S., St. Gelais, D., Roy, D. et LaPointe, G. Surveillance moléculaire de l’activité des ferments du lait. Forum Technologique Novalait, Bécancour, Québec. Mai 2006. Dallaire, R., Dewailly, É., Ayotte, P., Pereg, D., Dery, S., Côté, S., Dodin, S. Exposure to persistant organic pollutants in the Inuit population of Nunavik: temporal trends and potential health effects. 2nd ArticNet Annual Scientific Meeting, Banff, 13-16 décembre 2005. Delabre, JF, Babeu, JP, Boudreau, F, Rivard, N, Levy, E and Asselin, C. HNF4alpha is a key regulator of intestinal epithelial cell differentiation. 13e Congrès International de Gastroentérologie, 10-14 septembre 2005, Montréal. Diouf, P. N., Stevanovic, T., Cloutier, A. and Lizdaoui, A. (2006): Antioxidant proprieties of bark extracts of black spruce and trembling aspen. 3rd International Conference of Natural Health Products Society, Toronto, 3 au 5 mars 2006. Diouf, P. N., Stevanovic, T. Forest biomass as a source of biactive molecules. 3rd International Conference of Natural Health Products Society, Toronto, 3 au 5 mars 2006. Dodin, S. Produits de Santé Naturels et médicaments : mélange explosif. 1er Forum du Département de médecine familiale, Palais des Congrès, Rimouski, 25-27 mai 2006. Dodin, S. Traitement non hormonal des symptômes de la ménopause. Congrès annuel de l’Association des obstétriciens-gynécologues du Québec, Hilton du Lac Leamy (Gatineau), 11-14 mai 2006. Dodin, S., Marc, I., Blanchet, C. Un nouveau site internet destiné à l’enseignement d’une approche intégrée en santé. Journée annuelle de l’enseignement de la Faculté de médecine de l’Université Laval, Salle Omer Létourneau, Québec, 15 mars 2006. Doyon, A., Chouinard, P.Y., Tremblay, G.F. et Cinq-Mars, D. 2005. (Conférence sur invitation) Résultats de recherches caprines au Québec. Journée d’échanges et de réseautage à la chèvrerie expérimentale de Deschambault, organisée par Syndicat des producteurs de chèvres du Québec, Deschambault, 21 juin 2005. Doyon, A. et Chouinard, P.Y. (Conférence sur invitation) Influence de l’alimentation sur la composition du lait chez la chèvre : revue des travaux récents. Sera présentée au Colloque sur la chèvre 2005 L’innovation, un outil de croissance !, Saint-Hyacinthe, 7 octobre 2005. Eid, J., Côté, C., Fliss, I. et Jean, J. Inhibitory effect of natural peptide and protein against foodborne viruses. 2e Symposium de l’INAF, Québec, QC, 6-7 octobre 2005. Eid, J., Côté, C., Fliss, I. et Jean, J. Inhibitory effect of natural peptide and protein against foodborne viruses. International Association for Food Protection (IAFP) Meeting, Baltimore, MD, 14-17 août 2005 Eymard, S., Bryl, P., Carbonneau, M-E., Angers, P., Belkacemi, K. and Arul, J. 2005. Fractionation of seal oil by crystallization to obtain omega-3 fatty acids enriched fractions. 35th WEFTA Meeting, Antwerp, Belgium, September 19-22, 2005. Farnworth, E.R., Chouinard, P.Y., H. Jacques, S. Venkatramanan, A.A. Mafu, S. Defnoun, et P. Jones. Changes in the fecal microbiological and enzyme activity of subjects fed milk containing conjugated linoleic acid (CLA). Presented at the 18th International Congress of Nutrition. Nutrition Safari for Innovative Solutions, ICC, Durban, South Africa, 19-24 septembre 2005. Farnworth, E.R., Chouinard, P.Y., H. Jacques, S. Venkatramanan, I. Mainville, A.A. Mafu, S. Defnoun et P. Jones. The effect of drinking milk containing conjugated linoleic acid on fecal microbiological profile, enzymatic activity and fecal characteristic. Proceedings p. 82. Présenté à l’Annual Federal Food Safety and Nutrition Meeting, Ottawa, 19-21 octobre 2005. Fliss, I. Le contrôle des infections entériques par les probiotiques : des allégations et des preuves. Symposium international de Montréal : la santé par les probiotiques, vers des effets santé prometteurs. Gagnon D., Raymond Y., Vuillemard, J.-C. et Champagne, C.P. Étude des paramètres de propagation des ferments lactiques sur la production de diacétyle chez Lactococcus lactis ssp. lactis biovar diacetylactis 74311. 2e Symposium de l’INAF. Aliments fonctionnels et produits nutraceutiques : états des connaissances. Sainte-Foy, 6-7 octobre 2005. Gagnon, M., Jean, J., Darveau, A. et Fliss, I. In vitro diminution of adsorption of foodborne viruses by human bifidobacterial isolates. Association for Food Protection (IAFP) Meeting, Baltimore, MD, 14-17 août 2005. Goulet, C., Anguenot, R., Rivard, D. et Michaud, D. Protection of fragile proteins in transgenic potato lines expression a broad-spectrum proteinase inhibitor from tomato. Biennal General Congress of the International Proteolysis Society, Québec QC, 15-19 octobre 2005. Goulet, M.-C., Goulet, C., Dubuc J.-F. et Michaud, D. Adaptive evolution of plant cystatins, and modulation of their anti-papain inhibitory activity by single mutations at positively selected amino acid sites. Biennal General Congress of the International Proteolysis Society, Québec QC, 15-19 octobre 2005. Grenier, E, Maupas-Schwalm, F, Garofalo, C, Levy, E. Régulation de la synthèse et de la sécrétion de l’apo a-I et des HDL-C par l’acide rétinoïque. XXe Congrès annuel de la recherche des étudiants gradués et post-gradués, Centre de recherche, CHU-Ste-Justine, Montréal, 3 juin 2005. Grenier E, Maupas-Schwalm F, Garofalo C, Levy E. Effets de l’acide rétinoïque sur la production de l’apolipoprotéine A-1 et des HDL dans les cellules CACO-2. 47e réunion du Club de Recherches Cliniques du Québec, Bromont 29 sept. - 1 oct. 2005. Grenier E, Maupas F, Delvin E, Garofalo C, Levy E. Regulation of intestinal lipid synthesis, apolipoprotein biogenesis and lipoprotein assembly by retinoic acid. FASEB, San-Francisco, April 01-05, 2006. Grenier E, Maupas-Schwalm F, Trudel K, Garofalo C, Sané AT, Levy E. Effets de l’acide retinoïque sur la différenciation cellulaire, la biogenèse des apolipoprotéines et l’assemblage des lipoproteines. 7e réunion annuel de SQLNM, Québec, 27-29 avril 2006. Haddad, PS., Martineau, L., Couture, A., Spoor, D., Leduc, C., Benhaddou-Andaloussi, A., Joly, E., Harris, C., Burt, A., Bennett, S., Prentki, M., Arnason, JT. (2005). The lowbush blueberry Vaccinium angustifolium Ait. stimulates insulin secretion andexerts insulinomimetic and cytoprotective activities in vitro. International symposium on human Health effects of fruits and vegetables, Québec, August 17-20, p.19. Haddad, PS., Martineau, L., Spoor, D., Leduc, C., Benhaddou-Andaloussi, A., Harris, C., Meddah, B., Burt, A., Joly, E., Bennett, S., Prentki, M., Arnason, J. (2005). Bioassay-guided screening of the anti-diabetic potential of plants identified through an ethnobotanical survey of the Cree Nation of Mistissini in northern Quebec. Annual Symposium on Complementary Health Care, Exeter, UK. FACT 10 (Suppl. 1): 24. Hébrard G., Blanquet S., Beyssac E., Remondetto G., Alric M., Subirade M. 2005. Encapsulation de levures Saccharomyces cerevisiae recombinées dans une matrice de protéines de lactosérum en vue d’une administration orale, Colloque INAF, Québec, 6-7 octobre 2005. Jacques, H. Trans Fatty Acids and their Nutritional Impact in Human Studies. CIFST/AAFC 2006, Montréal, May 29, 2006. Jacques, H., Ouellet, V., Lavigne, C., Tremblay, F., Marette, A., Weisnagel SJ. La protéine de poisson : une clé dans la prévention du diabète ? Société Québécoise de Lipidologie, Nutrition et de Métabolisme, Québec, 28 avril 2006. Jacques, H., Ouellet, V., Weisnagel, J.-S., Lavigne, C., Tremblay, F., Marette, A. La protéine de morue et la sensibilité à l’insuline. Symposium de l’INAF, Québec, 7 octobre 2005. Jacques, H. (conférencière invitee) Trans fatty acids and their nutritional impact in human studies. CIFST/AAFC. Montréal, 29 mai 2006. Jacques, H., Ouellet, V., Lavigne, C., Tremblay, F., Marette, A., Weisnagel, SJ. La protéine de poisson : une clé dans la prévention du diabète ? Société québécoise de lipidologie, nutrition et métabolisme, Québec, 28 avril 2006. 49 INAF A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 Communications by INAF members Jacques, H., Ouellet, V., Weisnagel, SJ., Lavigne, C., Tremblay, F., Marette, A. La protéine de morue et la sensibilité à l’insuline. Symposium de l’INAF, Québec, 7 octobre 2005. Jones, P. 2006. Cycle of innovation for functional foods in Canada. Canadian Institute of Food Science and Technology and Agriculture and Agri-Food Canada Joint Conference. Montreal, Canada. Jones, P. 2006. The fats of life. Dietitians of Canada Annual National Conference. Halifax, Canada. Jones, P. 2006. Role of medium chain saturated fatty acids on cardiovascular disease risk factors. American Oil Chemists Society Annual Meeting. St Louis, USA. Jones, P. 2006. How research matters in functional food development. Prairie Research Day - University of Manitoba. Winnipeg, Canada. Jones, P. 2006. Fads and fallacies of functional fats. Its All About Fats Symposium - University of Alberta. Edmonton, Canada. Jones, P. 2006. Are functional foods on your grocery list? Seminar Presentation for AESES. Winnipeg, Canada. Jones, P. 2006. The path ahead for functional foods in Canada. Canada Grain Commission. Winnipeg, Canada. Jones, P. 2006. Functional foods in Canada: the path ahead - sow’s ear to silk purse. Manitoba Dental Association Meeting. Winnipeg, Canada. Jones, P. 2005. Advanced foods and materials network: partnerships between academia and industry. National Centres of Excellence Annual Meeting. Quebec City, Canada. Jones, P. 2005. Demystifying the funk about functional foods. Get to Know Research At University of Manitoba. Winnipeg, Canada. Jones, P. 2005. Functional foods – an overview. Canadian Society of Clinical Nutrition. Montreal, Canada. Jones, P. 2005. Plant sterols and their analogs in heart health management. Plant Sterol Media Event. London, England. Jones, P. 2005. Functional foods in Canada: the path ahead - sow’s ear to silk purse. Manitoba Farm Women’s Conference. Winnipeg, Canada. Kalantari, S., R. Corcuff, R. Boulanger, F.O. Duval et Arul, J. Effect of photochemical treatment on carotenoids and color development in post-harvest tomato fruit. ISHS FAV Health Conference, Québec, Qc, August 17-20 2005. Kheadr E, N. Darfouf, C. Le Lay, V. Ueli, L. Meile, C. Lacroix et Fliss, I. Frequent Occurrence of Bifidobacterium Thermacidophilum and Thermophilum in Newborn Feces. 8th symposium on lactic acid bacteria. Egmond aan Zee, The Netherlands, 28 août-1er septembre 2005. 50 Kheadr, E., C. Le Lay et Fliss, I. Contribution of Acid and Bile Stress to Antibiotic and Bacteriocin Sensitivity of Bifidobacteria. 8th symposium on lactic acid bacteria. Egmond aan Zee, The Netherlands, 28 août-1er septembre 2005. Lacroix, M. Les biosciences apprivoisées, Journée de la culture, conférence organisée par le Musée ArmandFrappier et intitulée : Les produits nutraceutiques, les bactéries probiotiques et les aliments fonctionnels. INRS-Institut Armand-Frappier. 30 septembre 2005. Kiggundu, A., Kunert, K., Michaud, D. The N-terminal trunk of plant cystatins determines their inhibitory specificity against cysteine proteinases. Plant Canada 2005, Edmonton AB, 15-18 juin 2005. Lacroix, M. Production and Application of Edible Films and Coating in Relation to Radiation Preservation of Food products, São Paulo, Instituto de Pesquisas Energéticas e Nucleares Superintendencia, Centre de Tecnologia das Radiações-CTR-IPEN-CNEN/SP, September 5 2005. Kiggundu, A., Goulet, C., Dubuc, J.-F., Kunert, K., Michaud, D. Modulating the papain inhibitory activity of a tomato cystatin by single mutations at a positively selected site. Plant Canada 2005. Edmonton AB, 15-18 juin 2005. Labbé D., Tremblay A., Bazinet L., Electromigration feasability of green tea catechins. Proceeding « International Congress on Membranes and Membrane Processes (ICOM 2005) », Séoul (Corée du Sud), 21-25 Août 2005, Section Bioseparation, Volume II, PM 126, pp. 1069-1070. Labbé D., Vignal E., Sistat P., Bazinet L. Separation of green tea catechins by electrodialysis with ultrafiltration membranes. Proceeding « International Symposium on Human Health: effects of fruits and vegetables (FAV Health 2005) », Québec, 17-20 août 2005. Labrie, S., M. Filteau, J. Audy, LaPointe, G. et Roy, D. Identification et analyse des déterminants génétiques responsables de la biosynthèse d’exopolysaccharides par la souche Bifidobacterium longum CRC-002. Symposium INAF, Québec, octobre 2005. Lachkar, D.P., Lamiot, E., Turgeon, S.L., Gauthier, S.F., Pouliot, Y. An experimental approach for the removal of caseins from bovine colostrum using of anionic polysaccharides, Annual meeting of the Canadian Institute of Food Scientists (CIFST), Montréal, 29 mai 2006. Lacroix, M. New ingredients and processes for improving functionality of natural packaging, Canadian Institute of Food Science and Technology, 2006 Annual meeting, Montreal May 28-30. Lacroix, M. Santé, nutraceutiques et transformation : Propriétés, fonctionnalités et usage des macromolécules et des métabolites secondaires d’origine végétale, microbienne et marine. Conférence sur la recherche et l’innovation Québécoises en Agriculture et en Agroalimentaire, (CRIQAA), Québec, 21-22 mars 2006. Lacroix, M. Polymères naturels et leurs applications dans le domaine bioalimentaire. Université Laval, dept. Chimie, Faculté des Sciences et de Génie. Le 23 janvier 2005. Lacroix, M. Antioxydant and antimutagenic properties of medicinals plants, vitamins and polyphenols from plants, spices, fruits and vegetables. CINVESTAV meeting, Irapuato, Mexico, November 11 2005. Lacroix, M. Immobilization of spices extracts on films and development of commercial bioactive food coatings. ExpoAgrofood, Irapuato, Mexico, November 10 2005. Lacroix, M. Irradiation of fruits and vegetables: Combination with hot dip and coating. 7th International Nuclear Atlantic Conference (INAC 2005), Santos, Brazil, August 28 – September 2. Lacroix, M. Présentation d’une conférence sur l’irradiation de carottes coupées à titre de membre du Comité d’experts International sur l’irradiation “3nd RCM on the Use of Irradiation to Ensure Hygienic Quality of Fresh, Pre-Cut Fruits and vegetables” Islamabad, Pakistan, 25-30 Juillet 2005. Lacroix, M. Use of natural antimicrobial with new food process to eliminate pathogenic bacteria in foods. First Verona International Joint meeting on Foods, Phytotherapic compounds and Health, University of Verona, Scientific Park of Verona and Ministry of Health, Italy, September 23-25 2005. Lacroix, M. Présentation d’une conférence intitulée : Antioxydant and antimutagenic properties of polyphenols in plants, fruits and vegetables. First Verona International Joint meeting on Foods, Phytotherapic compounds and Health, University of Verona, Scientific Park of Verona and Ministry of Health, Italy, September 23-25. Lacroix, N., Champagne, C.P., St-Gelais, D. et Vuillemard, J.C. Des cultures lactiques productrices d’acide y-amino butyrique (GABA) pour la préparation de produits laitiers à effet anti-hypertension. Forum Technologique Novalait, Bécancour, 30 mai 2006. Lacroix, N., C. Champagne, D. Saint-Gelais et Vuillemard, J.C. Caractérisation de ferments aromatiques produisants de l’acide y-amino-butyrique (GABA). 2e Symposium de l’INAF. Aliments fonctionnels et produits nutraceutiques : états et connaissances, Sainte-Foy, 6-7 octobre 2005. Lacroix, N., D. Gagnon, C. Champagne, D. Saint-Gelais et Vuillemard, J.C. 2005. Characterization of new aromatic starters with GABA-producing abilities. 8th Symposium on Lactic Acid Bacteria: Genetics, Metabolism and Applications. Pays-Bas, 28 août-1er septembre Lamarche, B. Débat : La prévention des maladies cardiovasculaires : Nutrition, Exercice et pharmacothérapie. Jusqu’où pouvons-nous aller ? Symposium Nutrition et Pharmacologie, Presented at the 6th Annual Meeting of the Société Québécoise de Lipidologie, April 2005, Ste-Foy, Québec, Canada. A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 INAF Communications by INAF members Lamarche, B. Les aliments fonctionnels et les nutraceutiques, une mode passagère ? Conférence grand publique la Presse/Radio-Canada, December 2005, Montréal. Lamarche, B. Gras trans et oméga-3 et santé vasculaire. Presented at the Conférence de la Société des sciences vasculaires du Québec : Le Consensus canadien sur les dyslipidémies, les gras-trans et omega-3 et la place des marqueurs échographiques carotidiens dans l’évaluation du risque vasculaire. January 2006, Montréal, Canada. Lamarche, B. Gras trans et santé cardiovasculaire. Présenté au Colloque NutraInnovation (CQVB) Élimination des gras trans : pourquoi et comment ? Février 2006, Québec. Lamarche, B. Institute on Nutraceuticals and Functional Foods: A Quebec-based research network on food and health. Presented at the Annual Meeting of the Canadian Institute on Foods Science and Technology, May 2006, Montréal, Canada. Lamarche, B. Emerging Foods and Nutrition Trends. Presented at the Annual Scientific Meeting of Health Canada. Oct 2005, Ottawa. Lamarche, B. Naturally occurring trans fatty acids vs. industrial trans fatty acids: comparison of their impact on the cardiovascular health. Presented at the 5th Annual Symposium on Nutrition organized by the Dairy Farmers of Canada, November 2005, Toronto, Montréal and Moncton. Lamarche, B. Waist and TG: Screening tools to detect patients with increased abdominal adiposity. Symposium on the Spectrum of CVD risk: Who should be treated and when? Presented at the International Symposium on TG and HDL: Role in CVD and the metabolic syndrome, July 2005, New York, USA. Lamarche, B. Dairy product consumption, the metabolic syndrome and cardiovascular disease: Is Quebec different from the rest of the world? February 2006, Tufts University, Boston, USA. Lamarche, B. The metabolic syndrome. Presented at the Denmark-Canada Workshop on Nutrigenomics. March 2006, Copenhagen, Denmark. Lambert, M, Levy, E, Delvin, E, Paradis, G, O’Loughlin, J, Hanley, JA. La surcharge pondérale et ses conséquences métaboliques et vasculaires chez un échantillon représentatif d’enfants et d’adolescents québécois. 3e colloque du réseau mère-enfant de la Francophonie, 9-10 juin 2005, Genève. Lamhoujeb, S., Charest, H., Fliss, I., Ngazoa, S., Jean, J. Phylogenetic analysis of norovirus isolates in Canadian gastroenteritis outbreaks between 2004 and 2005. Conférence conjointe ICSTA/Agriculture et Agroalimentaire Canada, Montréal, 28 au 30 mai 2006. Lam Quoc, A., Mondor, M., Lamarche, F., Ippersiel, D., Bazinet, L., Makhlouf, J. Quality improvement of cloudy apple juice by combining electrodialysis and mild heat treatment. Conférence présentée lors de la conférence conjointe ICSTA/AAC, « Emerging technology research » session. Montréal (Canada), 28-30 mai 2006. Lapointe, G. La biosynthèse des exopolysaccharides et leurs applications. 21e Congrès du Groupe Français sur les Glucides (France, mai 2006). Lapointe, G. Molecular aspects of microbial polysaccharide biosynthesis and their applications. University of Western Ontario, avril 2006. Lapointe, G. Exopolysaccharides : from genes to applications. CSM Annual Meeting (Halifax, juin 2005). LaPointe, G., D. Atlan & C. Gilbert. Molecular mechanisms controlling EPS biosynthesis in lactobacilli. 8e International Symposium on Lactic Acid Bacteria, The Netherlands. Août. 2005. Larue, B. et West, G. E. Colloque de l’Institut agricole du Canada intitulé « A la recherche de stratégies de soutien à l’agriculture durable au Canada », conférence invitée sur la perception des agricultures quant au OGM... 9 novembre 2005. Lavoie, C., Remondetto, G., Angers, P. et Subirade, M. Encapsulation des acides gras oméga 3 dans une matrice protéique : caractérisation et effet protecteur, Colloque INAF, Québec, 6-7 octobre 2005. Lavoie, C, Remondetto, G., Angers, P., Subirade, M. 2005. Encapsulation of omega-3 fatty acids in a protein matrix: characterization and protective effect study. Conference on Bioencapsulation, Kingston, pp 59-60, 24-26 juin 2005. Le Blay, G., A. Zihler, S. Vollenweider, C. Lacroix et Fliss, I. Evaluation of the sensitivity of common intestinal bacteria to lactic acid bacteria anti-microbial compounds and comparison with antibiotics. 8th symposium on lactic acid bacteria. Egmond aan Zee, The Netherlands, 28 août-1er septembre 2005. Leclerc, P.L., G. Remondetto et Subirade, M. Whey protein nanospheres as drug carriers for oral administration. 2st EUFEPS Conference on Optimising Drug Delivery and Formulation: Evaluation of Drug Delivery Systems Issues and Perspectives, qui se tiendra à Versailles en France, p.74, 20-23 novembre 2005. Leclerc P.L., G. Remondetto, C. Ramassamy, Subirade, M. Développement et caractérisation de nanosphères à base de protéines de lactosérum. Colloque INAF, Québec, 6-7 octobre 2005. Leclerc, PL, G. Remondetto, C. Ramassamy, Subirade, M. 2005. Whey protein nanospheres as drug carriers for oral administration. Conference on Bioencapsulation, Kingston, pp. 85-86, 24-26 juin 2005. Légaré, F., Stacey, D., Dodin, S., O’Connor, A., Richer, M., Tapp, S. Soutien à la prise de décision des femmes considérant l’utilisation des produits de santé naturels afin de soulager les symptômes associés à la ménopause : une évaluation de besoins. 8e Journée annuelle de la recherche de la Faculté de médecine de l’Université Laval, Québec, 31 mai 2006 (présentation de poster). Légaré, F., Stacey, D., Dodin, S., O’Connor, A., Richer, M., Tapp, S. Decision support for menopausal women considering the use of natural health products: A need assessment with proposed interventions. (poster presentation) The North American Research Conference on Complementary & Integrative Medicine, Edmonton, May 24-27 2006. Légaré, F., Stacey, D., Dodin, S., O’Connor, A., Richer, M., Tapp, S. Decision support for menopausal women considering the use of natural health products: A need assessment with proposed interventions. Health Canada International Symposium on Drug, Food and Natural Health Product Interactions, Château Cartier Resort, Aylmer, Canada, 9-10 février 2006. Lemieux, S. Alimentation méditerranéenne au Québec : est-ce possible et souhaitable. Conférence présentée dans le cadre du colloque annuel de l’INAF, octobre 2005. Lemieux, S. Des fruits et des légumes pour la santé du cœur. Conférence grand public, Québec, août 2005. Lemieux, S. Modifier les comportements alimentaires pour une saine gestion du poids corporel : pourquoi et comment ? Rencontre annuelle de la Société québécoise de lipidologie, de nutrition et de métabolisme, avril 2006, Québec. Lessard, M. 2005. Probiotics affect the establishment of T lymphocytes in the gut and prevent bacterial translocation in piglets. Oral presentation given at the Federal Food Safety and Nutrition Research Meeting, October 19 to 21, Government Conference Centre, Ottawa, Ontario. Lessard, J., Saint-Gelais D., Champagne C. et Vuillemard, J.C. Utilisation combinée d’un ferment thermophile et d’une souche mésophile aromatique pour la production de fromage en grains. Forum Technologique Novalait, Bécancour, 30 mai 2006. Le Tien C., Lafortune, R., Shareck F., Lacroix, M. DNA analysis by FT-IR spectroscopy of Pantoe agglomerans radioresistance. Pacifichem 2005, American Chemical Society Honolulu, Hawaii 15-20 décembre. Leung V., G. Remondetto, Subirade, M. Libération contrôlée de l’alpha-tocophérol par des émulsions gélifiées à froid de ß-lactoglobuline. Colloque INAF, Québec, 6-7 octobre 2005. Leung V, G. Remondetto, Subirade, M. Controlled Release of α-Tocopherol from Cold-set ß-Lactoglobulin Emulsion Gels. Conference on Bioencapsulation, Kingston, pp. 87-88, 24-26 juin 2005. Levy, E. Les grands défis de la recherche pédiatrique au 21e siècle, novembre 18, 2005. University Childrens Hospital Queen Fabiola, Bruzelles, Belgium. Levy, E. Triple threat obesity, insulin resistance and diabetes in pediatric patients, December 6th, 2005, Diabetes Centre, Hadassah University Hospital, Jerusalem, Israel. Levy, E. Oméga-3: substituts médicamentaux naturels durant le développement. Conférence des obstétriciens, February 17 2006, CHU Ste-Justine. 51 INAF A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 Communications by INAF members Levy, E. Réunion de groupe organisée par Génome Canada sur la nutragénomique, Copenhague, 14-16 mars 2006, Danemark. Levy, E. Stress oxydatif et inflammation. Symposium sur les maladies autoimmunes et inflammatoires : « Du fondamental à la clinique », 7 avril 2006, CHU Ste-Justine. Levy, E. Essentialité des acides gras oméga-3 durant la croissance et impact sur la santé et sur les risques de développer les maladies inflammatoires et cardiovasculaires à l’âge adulte. 7e réunion annuelle de la SQLNM, 26-29 avril 2006, Quebec. Levy, E. Sané, AT, Sinnett, D, Delvin, E, Bendayan, M, Ménard, D. Vers une compréhension du transport intestinal du cholestérol, sa relation avec l’athérosclérose et les traitements potentiels. 4e Symposium de physiopathologie du tube digestif, 17 juin 2005, Orford, Québec. Ligeret, H., Brault, A., Vallerand, D., Haddad, Y., Haddad, PS. (2006). Effect of silibinin on cold-warm reperfusion in an isolated perfused liver model. Proceedings of the Third Natural Health Products Research Conference, Toronto, March 3-5, 2006. Lin Teng Shee, F., Angers P., Bazinet L. Delipidation of a whey protein concentrate by electroacidification with bipolar membrane. Proceeding du « International Congress on Membranes and Membrane Processes (ICOM 2005) », Séoul (Corée du Sud), 21-25 août 2005, Section Desalination, PW 316, pp. 1415-1416. Lin Teng Shee, F., Angers P., Bazinet L. Precipitation of cheddar cheese whey lipids by electrochemical acidification. Proceeding du « International Congress on Membranes and Membrane Processes (ICOM 2005) », Séoul (Corée du Sud), 21-25 Août 2005, Section Novel Applications, Volume II, PW 317, pp. 1417-1418. Lin Teng Shee, F., Arul, J., Mateescu, M-A., Brunet, S. and Bazinet, L. 2005. Solubilisation du chitosane par électro-acidification avec membranes bipolaires. 2e Symposium de l’ INAF, Québec, Canada, 6-7 octobre 2005. Lin Teng Shee, F. ; Arul, J. ; Brunet, S. ; Mateescu, A.-M. ; Bazinet, L. Solubilization of chitosan by bipolar membrane electro-acidification. Conférence présentée lors du 17ème meeting annuel de la North American Membrane Society, « Electrodialysis » session. Chicago (USA), 12-17 mai 2006. Lin Teng Shee, F., Arul, J., Brunet, S., Mateescu, AM, Bazinet, L. Une nouvelle méthode de solubilisation du chitosane par électrodialyse avec membranes bipolaires. Poster présenté au MEMPRO 3 Intégration des membranes dans les procédés, Nancy (France) 5-7 avril 2006. Lin Teng Shee, F., Angers, P., Bazinet, L. Electro-précipitation des lipides du lactosérum par membranes bipolaires. Poster présenté au MEMPRO 3 Intégration des membranes dans les procédés, Nancy (France) 5-7 avril 2006. 52 Marc, I., Rainville, P., Verreault, R., Vaillancourt, L., Masse, B., Dodin, S. The use of hypnosis to improve pain management during voluntary interruption of pregnancy: a preliminary open study. The North American Research Conference on Complementary & Integrative Medicine, Edmonton, 24-27 mai 2006. Marc, I., Rainville, P., Verreault, R., Vaillancourt, L., Masse, B., Dodin, S. Reduction of pain medication during the first trimester surgical abortion by a brief hypnotic intervention. The North American Research Conference on Complementary & Integrative Medicine, Edmonton, 24-27 mai 2006. Marcil, V, Lavoie, JC, Tremblay, A, Levy, E. Influence du stress oxydatif sur le transport de cholestérol et l’athérogenèse. 7e réunion annuel de SQLNM, 27-29 avril 2006, Québec. Marcil, V, Comte, B, Lavoie, JC, Tremblay, A, Charté, M, Thibault, L, Zoltowska, M et Levy, E. Transport de cholestérol dans les macrophages : modulation dans le stress oxydatif. 47e réunion du Club de Recherches Cliniques du Québec, Bromont, 29 sept - 1er oct. 2005 Marsolais, JF et West G. Health through bioactive food components: Do general practitioners in Québec think it’s possible?, Symposium scientifique de l’IN-CAM à Toronto, le 12 et le 13 novembre 2005. Maupas-Schwalm, F, Sané, AT, Marcil V, Trudel, K, Salvayre, R, Nègre-Salvayre, A, Levy, E. Inhibition par les HDL de la surexpression du récepteur UPAR induit par le stress oxydant dans des cellules vasculaires humaines en culture : une nouvelle potentialité anti-athérogène des HDL? XXe Congrès annuel de la recherche des étudiants gradués et post-gradués, Centre de recherche, CHU-Ste-Justine, Montréal, 3 juin 2005. Mendez, L, Makhlouf, J., Ratti, C. 2005. Garlic quality properties during constant convectiv drying. 3rd, Inter-American Drying Conference, 21-23 août, Montréal, Québec. Michaud, D. 2006. Outils protéomiques pour la caractérisation des végétaux et aliments nouveaux. Séminaires de la Faculté des Sciences de l’Université de Moncton, Moncton NB, 29 mars. Marcil, V, Tremblay, A, Lavoie, J-C, Levy, E. Modulation of cholesterol transport by oxidative stress in THP-1 macrophages. FASEB, San-Francisco, April 01-05, 2006 Michaud, D. 2006. Proteomic analysis of GM plants and foods. Health Canada/CFIA Evaluator’s Workshop 2006, Ottawa ON, 23-24 février. Marette, A. CFBS meeting, Symposium on « Metabolic Dysregulation in Obesity and Type 2 Diabetes », Guelph, ON, June 24, 2005. Title: « iNOS: an autocrine/paracrine inflammatory mediator of insulin resistance in obesity ». Mo, F., Harris, CS, Ryan, SD, Haddad, PS, Staines, WA, Arnason, JT, Bennett, SAL. 2006. Plant phenolics as novel inhibitors of platelet activating factor-induced neuronal cell death. Proceedings of the Third Natural Health Products Research Conference, Toronto, Mar. 3-5, 2006. Marette, A. 2005 NAASO meeting on Obesity, Vancouver, Canada, Oct. 15-19, 2005. Title: « Role of the mTOR/S6K1 pathway in obesity-driven insulin resistance ». Marette, A. CDA CDA/CSEM Professional Conference and Annual Meetings, Edmonton, Alberta, October 19-22,2005. Young Scientist Award lecture. Marette, A. Vanderbilt University, Nashville, Title: Inflammation and nutrient sensing mechanisms leading to insulin resistance in obesily-linked diabetes. Jan 26, 2006. Marette, A. VIIth Edition of the State of São Paulo Congress of Diabetes and Metabolism, Guaruja, Brazil, Title: “The role of iNOS in promoting insulin resistance in inflammatory diseases” May 5, 2006. Marsolais, J.-F., West, G. E., Ouellet, D. et Lemieux, S. Opinion, croyances et connaissances des diététistes du Québec sur les aliments fonctionnels et les nutraceutiques. Affiche présentée à la rencontre technologique « Nutraceutiques et aliments fonctionnels : états et connaissances » organisé par l’INAF et le CQVB, Hôtel Plaza, Ste-Foy, Québec, octobre 2005. Marsolais, JF et West G. Opinions, croyances et connaissances des diététistes du Québec sur les aliments fonctionnels et les nutraceutiques , [Affiche], 2e symposium scientifique de l’INAF organisé en collaboration avec le CQVB : AFN : états et connaissances, Hôtel Plaza, Québec, Québec, le 6 & 7 octobre 2005 Montoudis, A, Delvin, E, Ménard, D, Bendayan, M, Beaulieu, JF, Garofalo, C, Levy, E. Implication du I-FABP dans le transport intestinal des acides gras vers les organelles cellulaires. 7e réunion annuel de SQLNM, 27-29 avril 2006, Québec. Montoudis, A, Delvin, E, Ménard, D, Bendayan, M, Beaulieu, JF, Garofalo, C, Levy, E. Est-ce que le I-FABP, transporteur cellulaire des acides gras est indispensable à l’absorption intestinale des lipides ? XXe Congrès annuel de la recherche des étudiants gradués et post-gradués, Centre de recherche, CHU-Ste-Justine, Montréal, 3 juin 2005. Morin, P., Jimenez-Flores, R., Pouliot, Y. Comparative study of fractionation of whey and regular buttermilk. Sommet mondial laitier de la FIL, Vancouver, 20 septembre 2005. A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 INAF Communications by INAF members Morin, P., Jimenez-Flores, R., Pouliot, Y. Effect of processing on the composition and structure of buttermilk and of its milk fat globule membranes. ADSA-ASAS Joint Meeting, Minneapolis, MN, USA, 9-13 juillet 2006. Morin, P., Jimenez-Flores, R., Pouliot, Y. On the fractionation of buttermilk using microfiltration membranes, North American Membrane Society (NAMS) Annual Meeting, Chicago, 14-18 mai 2006. Morin, P., Jimenez-Flores, R., Pouliot, Y. Comparative study of fractionation of whey and regular buttermilk, 2e Symposium de l’INAF, Québec, 6-7 octobre 2005. Moroni, O., E.E. Kheadr, C. Lacroix et Fliss, I. Sensitivity of Food-Borne Listeria Monocytogenes against Antibiotics and Bacteriocin-Like Molecule produced by Bifidobacterium Thermacidophilum Strains Isolated from Infant Feces. 8th Symposium on Lactic acid Bacteria. Egmond aan Zee, The Netherlands, 28 août-1er septembre 2005. Moroni, O., Y. Boutin, C. Lacroix et Fliss, I. Evaluation of the ability of three bacteriocin-producing bifidobacteria of human origin to inhibit the translocation of food-borne Listeria monocytogenes. 8th symposium on lactic acid bacteria. Egmond aan Zee, The Netherlands, 28 août-1er septembre 2005. Nicolas, G., LaPointe, G. et M.C. Lavoie. Purification et caractérisation des mutacines F-59.1 et I-T9. 74e Congrès de l’ACFAS, Montréal, QC, mai 2006. O’Loughlin, J, Lambert, M, Paradis, G, Hanley, J, Karp, I, Delvin, E, Levy, E. Association between C-reactive protein and tobacco use in a representative, populationbased sample of children and adolescents. Canadian Society for Epidemiology and Biostatistics 2005, Toronto. Ouellet, D., West, G. E., La santé par les composants bioactifs des aliments : ce qu’en pensent les professionnels de la santé, COLLOQUE STA – St-Hyacinthe-conférence invitée, 12 novembre 2005. Ouellet, D. et West, G. Les décisions administrative du service alimentaire : peut-on faire une différence quant aux risques de malnutrition. Colloque de l’Institut Universitaire de Gériatrie de Montréal, mars 2006. Ouellet, V., Weisnagel, SJ, Marette, A., Marois, J., Bergeron, J, Jacques, H. Impact de la consommation de protéine de morue sur les lipoprotéines plasmatiques et la protéine C-réactive chez des sujets humains insulinorésistants. 7e réunion annuelle de la Société québécoise de lipidologie, de nutrition et de métabolisme, 27-29 avril 2006, Québec. Médecine/Sciences 2006, vol. 22 : résumé 248, p.xv. Ouellet, V., Marois, J., Weisnagel, S.J., Marette, A., Bergeron, J, Jacques, H. Amélioration de la sensibilité à l’insuline suite à la consommation de protéine de poisson vs diverses autres protéines animales chez des sujets résistants à l’insuline. Congrès annuel du Conseil professionnel de diabète du Québec, 18-19 novembre 2005, Québec, Canada. Ouellet, V., Marois, J., Weisnagel, SJ, Marette, A., Bergeron, J., Jacques, H. Plasma lipoprotein response in insulin resistant subjects fed fish protein or other animal protein. Canadian Society for Clinical Nutrition, 4th annual Scientific Conference Nutrition in Health and Disease: Focus on Obesity and Gastrointestinal Disorders. Sept. 8-10, 2005, Montréal, Canada, Program at a glance, Abstract #4 Plourde, M., Ledoux, M., Fontaine, J.J., Carpentier, Y., Chardigny, J.M., Angers, P. and Sébédio, J.L. Comparative effects of conjugated linoleic and a-linolenic acid on experimental atherosclerosis in hamsters. 26th World Congress and Exhibition of the ISF, September 2005, Prague, Czech Republic. Poulin, J.-F.; Amiot, J. ; Bazinet, L. Electrodialysis with ultrafiltration membrane: a new way for simultaneous purification of basic and acid bioactive peptides. Conférence présentée lors du 17ème meeting annuel de la North American Membrane Society, « Chromatographic and other membranes for the pharmaceutical industry » session. Chicago (USA), 12-17 mai 2006. Poulin, V., P.Y. Chouinard, C. Gariépy, A. Fournier et J. Jacob. 2006. Effets de l’huile de soya et des implants sur les performances et la qualité de la viande. Journée Innovation et Progrès en Agroalimentaire au Centre du Québec (INPACQ-Bovin) Un avant-goût de l’avenir. Ministère de l’Agriculture des Pêcheries et de l’Alimentation du Québec. 18 février. Notre Dame du Bon Conseil, QC. Preradov, A. et Michaud, D. 2006. Monitoring gene/protein-inducing effects of benzothiadiazole in tomato by surface-enhanced laser desorption-ionization/ time-of-light mass spectrometry. Annual Meeting of the Biocontrol Network, Kananaskis Village (Alberta), 2-4 février. Punthakee, Z, Delvin, E, O’Loughlin, JO, Paradis, G, Levy, E. Lambert, M. Distribution of plasma adiponectin in youth and its relation with adiposity pubertal status and fasting insulin levels. Endo Society 2005. Radanielina, P., Arul, J., Belkacemi, K., Chouinard, Y. and Angers, P. 2006. Oxidative stability of conjugated linoleic acid in CLA-enriched butter oil. 97th AOCS Annual Meeting, St. Louis, MO, April 30-May 3. Raharitsifa, N., Genovese, D. and Ratti, C. "Characterization of apple juice foams". 2005. IFT (Institute of Food Technology) Conference. New Orleans, 17-21 July, 2005. Rajkumar, P., Kailappan, R., Raghavan, G.S.V., Vishwanathan, R. and Ratti, C. "Studies on Foam Mat Drying of Alphonso Mango Pulp". 2005. IADC 2005 (Inter-American Drying Conference), August 21-23, Montreal, Canada. Ramassamy, C. Investigation of neuroprotective effects of polyphenolic compounds from plants, nutraceuticals, food and diet. Application in neurodegenerative diseases. May 2006, Hong Kong University, Pasteur Institute HK. Ramassamy, C. Mécanismes neuroprotecteurs des composés polyphénoliques. Hanoi, Vietnam, décembre 2005. Poulin, JF; Amiot, J.; Bazinet, L. Fractionnement simultané de peptides bioactifs acides et basiques par un procédé d’électrodialyse avec membrane d’ultrafiltration. Poster présenté au MEMPRO 3 Intégration des membranes dans les procédés, Nancy (France) 5-7 avril 2006. Ramassamy, C. Nutraceutiques et santé cérébrale : un lien radical. Symposium INAF, CQVB, Université Laval, Québec, octobre 2005. Poulin JF, Amiot J., Bazinet L. Fractionation of bioactive peptides by electrodialysis with ultrafiltration membrane. Poster présenté lors de la conférence conjointe ICSTA/AAC. Montréal (Canada), 28-30 mai 2006. Ratti, C. et T. Kudra. “Drying of foamed materials: opportunities and challenges”. Actes de Congrès de la Conférence 11th Polish Drying Symposium. Pologne, 13-16 septembre 2005. Pouliot, Y., Gauthier, S.F., Lamiot, É. (Conférence sur invitation) Molecular properties and extraction of milk growth factors. 20th Annual J.R. Brunner Protein Symposium, Michigan State University, USA, 17-18 mai 2006. Reid- Ainsley, A., Desrumaux, A., Poncelet, D., Makhlouf, J. et Vuillemard, J.C. 2005. Stability study on water-in-oil-in-water multiple emulsion (and encapsulation of nutraceuticals. Worldnutra Exibition 2005, 16-19 octobre, Anaheim, Californie. Pouliot, Y., Gauthier, S.F. (Conférence sur invitation) Bovine milk: a source of bioactives. Meeting of CARC (Canadian Agri-food Research Council), 17 novembre 2005, Ottawa. Reid- Ainsley, A., Desrumaux, A., Poncelet, D., Makhlouf, J. et Vuillemard, J.C. 2005. Étude de la stabilité d’émulsions multiples de type eau/huile/eau. 2ième Symposium de l’INAF, 6-7 octobre, Québec. Pouliot, Y., Gauthier, S.F. Les nouveaux bioactifs du lait. 2e Symposium de l’INAF, Aliments fonctionnels et produits nutraceutiques : états et connaissances. Québec (Qc), 6-7 octobre 2005. Pouliot, Y., Gauthier, S.F. (Conférence sur invitation). Bioactive peptides: opportunities for dairy and non-dairy products. IDF-World Dairy Summit 2005, Vancouver (CA), 17-22 septembre 2005. Reid- Ainsley, A., Desrumaux, A., Poncelet, D., Makhlouf, J. et Vuillemard, J.C. 2005. Étude de la stabilité d’émulsions multiples de type eau/huile/eau. Club Émulsion 2005, 26-27 septembre, Montpellier, France. Pouliot, Y., Gauthier, S.F., (Conférence sur invitation). Whey proteins as a source of bioactive peptides. Whey protein symposium. IFT Annual Meeting, New Orleans (Louisiana), 16-20 juillet 2005. 53 INAF A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 Communications by INAF members Remondetto G, P.L. Leclerc, R. Caillard et Subirade, M. Protein-based hydrogels as nutraceuticals delivery system: the case of quercetin. FAV Health, Symposium international sur les effets santé des fruits et légumes, Québec, 17-20 août 2005. Roufik, S., Gauthier, S.F., Turgeon, S.L. Evidence of complex formation between ß-lactoglobulin and the antihypertensive peptide ß-Lg f142-148 and in vitro digestibility of the complex. 2e Symposium de l’INAF, Aliments fonctionnels et produits nutraceutiques : états et connaissances. Québec (Qc), 6-7 octobre 2005. Roufik, S., Gauthier, S.F., Turgeon, S.L., Thermodynamics of binding interactions between bovine ß-lactoglobulin and the antihypertensive peptide ß-LG 142-148. IDF-World Dairy Summit 2005, Vancouver (CA), 17-22 september 2005. Roy, D. 2006. Chaire de recherche CRSNG-industrie laitière sur la technologie et la Typicité fromagère. Forum Novalait 2006, 30 mai 2006, Bécancour, Québec. Roy, D. 2005. Le point sur les bifidobactéries et la santé. Colloque INAF, 5 octobre 2005. Roy, D. La Santé par les probiotiques : Applications dans ce troisième millénaire. (D. Roy, Éditeur scientifique.) Actes du Symposium international de Montréal 2004. Edisem, St-Hyacinthe. Édité en 2005. Rusu, D., Bouchard, L., Gauthier, S., Pouliot, Y., Poubelle, P. Effets d’un composé protidique extrait du lactosérum bovin sur la production d’anions superoxyde et la dégranulation des neutrophiles humains normaux in vitro. 4e Journée Scientifique du CRRI, Québec (Qc), 21 novembre 2005. Saint-Sauveur, D., Gauthier, S.F., Boutin, Y. Immunomodulating properties of whey protein isolates and their peptides released by enzymatic digestion. 2e Symposium de l’INAF, Aliments fonctionnels et produits nutraceutiques : états et connaissances. Québec (Qc), 6-7 octobre 2005. Samane, S., Noël, J., Charrouf, Z., Amarouch, H., Haddad, PS. (2005). Insulin-sentizing and antiproliferative effects of Argania spinosa seed extracts. International symposium on human Health Effects of Fruits and Vegetables, Québec, August 17-20, p.66. Sané, AT, Marcil, V, Sinnett, D, Delvin, E, Bendayan, M, Ménard, D, Beaulieu, JF, Levy, E. Niemann-pick c1like 1 (npc1l1) et le transport intestinal du cholesterol. 7e réunion annuel de SQLNM, 27-29 avril 2006, Québec. Sané, AT, Sinnett, D, Levy, E. Implication du NPCL1 dans le transport intestinal du cholestérol. XXe Congrès annuel de la recherche des étudiants gradués et post-gradués, Centre de recherche, CHU-Ste-Justine, 3 juin 2005, Montréal. Sané, AT, Marcil, V, Sinnett, D, Delvin, E, Bendayan, M, Ménard, D, Beaulieu, JF et Levy, E. Niemann-Pick C1 Like 1 (NPC1L1) et le transport de cholestérol. 47e réunion du Club de Recherches Cliniques du Québec, Bromont 29 sept.- 1er oct. 2005. 54 Saucier, L. et Bernier, J.F. 2005. L’utilisation des antimicrobiens en production animale : Le bénéfice en vaut-il le risque ? 68e Congrès annuel de l’Ordre des agronomes du Québec, 17 juin, Québec. Schreyer, A., Chapuzet, J-M., Bazinet, L., Britten, M., Lessard, J. Étude de la régulation électrochimique du potentiel redox du lait pour améliorer son entreposage et/ou sa transformation ultérieure. Conférence présentée au symposium « Journées d’électrochimie », Saint-Malo (France), 5-8 Juillet 2005. Schreyer, A., Britten, M., Chapuzet, JM, Lessard, J., Bazinet, L. Capacité anti-oxydante et résistance au stress oxydatif d’un lait pasteurisé. Poster présenté lors du Forum technologique de Novalait Miser sur l’Innovation pour agir face aux changements. Bécancour (Qc). 30 mai 2006. Schreyer, A., Britten, M., Chapuzet, JM, Lessard, J., Bazinet, L. Capacité anti-oxydante et résistance au stress oxydatif d’un lait pasteurisé écrémé électroréduit. Poster présenté lors de la troisième édition de la Conférence sur la Recherche et l’innovation Québécoise en Agriculture et en Agroalimentaire. Québec (Qc). 21-22 mars 2006. Schreyer, A., Chapuzet, JM. Bazinet, L., Britten, M., Lessard, J. Étude de la régulation électrochimique du potentiel redox du lait pour améliorer son entreposage et/ou sa transformation ultérieure. Poster présenté au MEMPRO 3 « Intégration des membranes dans les procédés », Nancy (France) 5-7 avril 2006. Seidman, E, Bouthillier, L, Amre, D, Drouin, E, Deslandres, C, Levy, E. Controlled trial on the effects of exclusive enteral nutrition therapy using a semielemental antioxidant enriched formula vs steroids on antioxidant and nutritional status in pediatric Crohn’s Disease. 13e Congrès International de Gastroentérologie, 10-14 septembre 2005, Montréal. Spahis, S, Delvin, E, Ziv, E, Elchebly, M, Lambert, M, Levy, E. peut-on amoindrir les aberrations du transport intestinal des lipides par les acides gras n-3 dans le diabète de type 2 ? 7e réunion annuel de SQLNM, 27-29 avril 2006, Québec. Spahis, S, Delvin, E, Ziv, E, Lambert, M, Levy, E. Rôle bénéfique des acides gras w-3 dans le syndrome métabolique dans le modèle animal Psammomys obesus. 47e réunion du Club de Recherches Cliniques du Québec, Bromont 29 sept.- 1er oct. 2005. Spahis, S, Delvin, E, Ziv, E, Lambert, M, Levy, E. Régulation de l’absorption intestinale des lipides par les acides gras n-3. XXe Congrès annuel de la recherche des étudiants gradués et post-gradués, Centre de recherche, CHU-Ste-Justine, 3 juin 2005, Montréal. Stacey, D., Légaré, F., Dodin, S., O’Connor, A., Richer, M., Tapp, S. Decision support for menopausal women considering the use of natural health products: A need assessment. 31st Annual Meeting of the North American Primary Care Research Group (NAPCRG), Québec, 15-18 octobre 2005. Stacey, D., Légaré, F., Dodin, S., O’Connor, A., Richer, M., Tapp, S. Integrated decision support program regarding the use of natural health products for menopausal women: a need assessment. 31st Annual Meeting of the North American Primary Care Research Group (NAPCRG), Québec, 15-18 oct. 2005. Stacey, D., Légaré, F., Dodin, S., O’Connor, A., Richer, M., Tapp, S. Programme intégré de soutien à la prise de décision en matière de produits de santé naturels pour les femmes d’âge moyen vivant la transition ménopausique et celles ménopausées : étude des besoins. Centre de recherche du CHUQ, Québec, 7 juillet 2005. Stevanovic, T. Mars 2006 : Centre de coopération internationale en recherche agronomique pour le développement (CIRAD), Montpellier, France : « Constituants du bois et l’utilisation agroécologique des BRF ». Stevanovic, T. Février 2006 : Centre des techniques agronomiques (CTA), Strée, Wallonie, Belgique : « Constituants du bois et la pédogenèse à partir des BRF ». Stevanovic, T. et J-M. Lavoie (2005): “Bioactive molecules are available from Canadian birches for aplications in cosmetic, pharmaceutical and food industries”. X reunion sobre investigacion y desarollo de productos forestales. International Academy of Wood Science Meeting. Conception, Chili, 14 à 17 novembre 2005. Subirade, M. Conférencière. Microencapsulation of bioactive food compounds: a means to increase their bioavailability. Conference on Bioencapsulation, Kingston, 24-26 juin 2005, p. 39-40. Subirade, M. Conférencière invitée Les protéines, les bio-systèmes et les aliments fonctionnels. Colloque des étudiants de chimie, Sherbrooke, 2005. Subirade, M. et L. Chen. Conférencière. Bioprotection des molécules nutraceutiques : un facteur clé pour le développement d’aliments fonctionnels. Colloque INAF, Québec 6-7 octobre 2005. Subirade, M. Conférencière invitée. Les biopolymères alimentaires comme vecteurs de molécules actives : défis et opportunités, atelier Encapsulation et Enrobage, Fondation des Gouverneurs, Saint-Hyacinthe, Québec, 1er février 2006. Tahiri, I., Desbiens, M., Benech, R., Kheadr, E., Lacroix, C., Thibault, S., Ouellet D., Fliss, I. Characterization of divergicin M35 and its antilisterial activity in cold-smoked salmon. Conférence conjointe ICSTA/AAC 2006, Montréal du 28 au 30 mai. Tchernof, A. Changements hormonaux chez la femme : syndrome prémenstruel, migraine, ménopause, ostéoporose et composition corporelle. Invited lecture. Formation Harmonie Santé. Octobre 2005. A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 INAF Communications by INAF members Tchernof, A. Ovarian hormone deficiency and the pathophysiology of abdominal obesity. Invited lecture. Experimental Biology, San Francisco, 2006. Tremblay, A. « L’obésité : une réalité bien présente… mais encore mal comprise », présenté dans le cadre des conférences-midi du groupe Astral Media, Montréal, mai 2006. Tian, Z., Bryl, P., Carbonneau, Arul, J., M.-E., Garro, J.M. and Angers, P. 2006. Multi-step urea fractionation of marine oils: Production of fractions high in saturated, in monounsaturated or in polyunsaturated fatty acids. 97th AOCS Annual Meeting, St. Louis, MO, April 30-May 3, 2006. Tremblay, A. « Le cœur de l’obèse… qui a bien besoin d’interventions multidisciplinaires », présenté dans le cadre des rencontres hebdomadaires du groupe de médecine familiale de Rivière-du-Loup, Rivière-du-Loup, mai 2006. Tremblay, A. « Habitudes de vie et obésité », co-présenté avec Michel Beauchemin dans le cadre de trois mini-forums régionaux sur l’obésité, Québec, - Neuville – Charlesbourg, juin 2005. 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Profil génomique de la cellule épithéliale intestinale humaine le long de l’axe crypte-villosité. 4e Symposium de physiopathologie du tube digestif, 17 juin 2005, Orford, Québec. Tremblay, A. « Capsaicin and energy balance », présenté dans le cadre du Congrès international FAVHEALTH 2005, Québec, août 2005. Tremblay, A. « Management of obesity: lifestyle modification », présenté dans le cadre du « World Congress of Gastroenterology », Montréal, septembre 2005. Tremblay, A. « Alimentation et obésité chez les personnes âgées : les défis et les solutions de demain », présenté au Centre Hospitalier Pierre-Le Gardeur, septembre 2005. Tremblay, A. « Toxins and Obesity : the Case of Organochlorines », présenté dans le cadre de la rencontre scientifique annuelle de NAASO – The Obesity Society, Vancouver, octobre 2005. Tremblay, A. « Obésité », présenté dans le cadre de la série de conférences « Les rendez-vous du mercredi » du Programme des activités pour les 50 ans et plus, Québec, octobre 2005. Tremblay, A. « L’obésité à l’adolescence », présenté dans le cadre de « Les Entretiens de Pédiatrie 2005 », Québec, novembre 2005. Tremblay, A. « L’obésité : notre perception des causes est-elle juste ? », présenté dans le cadre des Conférences en santé publique de la région de Québec, Québec, décembre 2005. Tremblay, A. « Food intake and human activity: a physiological perception », présenté dans le cadre du WCFS Food Summit, Wageningen, décembre 2005. Tremblay, A. « L’obésité… bien plus qu’un problème de malbouffe et de sédentarité », présenté dans le cadre des Conférences Desjardins, Centre de recherche de l’Hôpital Laval, Québec, avril 2006. Tremblay, A. « Travail de l’esprit et bilan énergétique », présenté dans le cadre de la réunion annuelle de la Société québécoise de lipidologie, de nutrition et de métabolisme, Québec, avril 2006. Trudel, K, Garofalo, C, Delvin, E, Sinnett,, Levy, E. Paraoxonase 2: expression tissulaire et role protecteur contre le stress oxydatif. XXe Congrès annuel de la recherche des étudiants gradués et post-gradués, Centre de recherche, CHU-Ste-Justine, 3 juin 2005, Montréal. Trudel, K, James, RW, Sinnett, D, Delvin, E, Levy, E. Site de localisation de la paraoxonase 2 (PON 2) et modulation par le stress oxydatif. 47e réunion du Club de Recherches Cliniques du Québec, Bromont, 29 sept.- 1er oct. 2005. Turgeon, S.L. et X.J. Leng. Functionality of ProteinPolysaccharide in Dairy Applications. Sommet mondial laitier de la FIL.. Vancouver, 17-22 septembre 2005. Vlad, M., Dehouche, Z., Hamoudi, S., Arul, J. and Belkacemi, K. 2006. Lactose Oxidation to Lactobionic Acid over a New Bimetallic Bi-Pd Supported on SBA-15 Nanostructured Silica Material. 19th Canadian Symposium on Catalysis, Saskatoon, SK, May 14-17, 2006. Vohl, M.-C., Gene-diet interactions and cardiovascular risk factors. CSCN 4th Annual Scientific Meeting, September 10, 2005, Montreal, Canada. Vuillemard, JC, Saint-Gelais, D. et Champagne, C. Caractérisation des activités biologiques et du potentiel technologique de souches bactériennes isolées de ferments lactiques naturels. Fiche Trans-info. Forum technologique Novalait. Bécanacour. 30 mai 2006. Vuong, T., Matar, C., Ramassamy, C., Haddad, PS, (2005). La fermentation du jus de bleuet (Vaccinium angustifolium Ait) augmente ses effets insulinomimétiques chez les cellules musculaires C2C12 et adipeuses 3T3-L1. 2e symposium de l’INAF : États des connaissances, 6-7 octobre 2005, Québec, Canada. Vuong, T., Haddad, P.S., Matar, C., Ramassamy, C. (2005). Étude comparative du potentiel neuroprotecteur du jus de bleuet fermenté et non-fermenté (Vaccinium angustifolium Ait). 2e symposium de l’INAF : États et connaissances, 6-7 octobre 2005, Québec, Canada. Vuong, T., Haddad, P.S., Matar, C., Ramassamy, C. (2005). Étude comparative du potentiel neuroprotectur de jus de bleuet fermenté et non-fermenté (Vaccinium angustifolium Ait). Congrès Armand-Frappier, 3-5 novembre 2005, Québec, Canada. West, G. et al. (Conférencière invitée) Consommateurs anti-OGM versus producteurs agricoles pro-OGM : Est-ce vrai ? Colloque Sécurité alimentaire et OGM, Pavillon La Laurentienne de l’Université Laval, Organisé par CÉDÉ de l’UL; IREDE de l’U. Sciences sociales de Toulouse; 20 septembre 2005 West, G. E. “To whom should I turn? Family doctors & nutritionists divergent views on functional foods and health.” Department of Ressource Economics and Policy, University of Maine, Orono, Maine, April 17, 2006. West, G. E. Seminar at the Guelph Food Technology Centre “Product Innovation with Dairy Ingredients”. Consumer musings over the value of milk ingredients: is it better to seek than to avoid?, Guelph, Ontario, 23 mars 2006. West, G. E. Présentation pour la « journée du CRÉA ». Molécullivre : les agriculteurs sont-ils intéressés dans un contexte anti-OGM ? Québec, Québec, 17 mars 2006. West, G.E. Connaissances et recommandations des AFN parmi les médecins et les nutritionnistes. Table ronde : Vocation préventive et thérapeutique de l’aliment : sachez doser !, Les conférences La Presse et Radio-Canada, « Alimentation : assaisonner votre propos ! » Montréal, Québec, 5 décembre 2005. West, G. E. Consmmateurs et producteurs des OGM, Genomic Research Centre, Irapuato, Guanajuato, Mexico, 10 et 11 novembre 2005 West, G. E. Nutraceutic Conferences, market potential for FFN: How interested are consumers and health professionals? Irapuato, Guanajuato, Mexico, 10 et 11 novembre 2005. West, G. E. La place des aliments fonctionnels et des nutraceutiques dans la pratique des omnipractiens et des nutritionistes. Rencontre technologique « Nutraceutiques et aliments fonctionnels : états et connaissances » organisé par l’INAF et le CQVB, Hôtel Plaza, Ste-Foy, Québec, 7 octobre 2005. West, G. E. Produits naturels : recommander ou ne pas recommander, Colloque annuel de l’Ordre Professionnel des Diététistes du Québec, « Que connaissons-nous des produits naturels ? » Montréal, Québec, 30 septembre 2005. 55 INAF A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 Postdoctoral fellows P ROJ ECTS I N P RO G R ESS Students Directors Starting date Finish date Project title Atifi, Sahim Arul, Joseph* Belkacemi, Khaled 2006/05 - Production de chitosan en utilisant des réacteurs sonochimiques Blachère, Jean-Christophe Cunnane, Stephen* 2005/07 - Ketogenesis and lipid-lowering drugs Bouchard, Luigi Vohl, Marie-Claude* 2005/01 - Genomic insights into the metabolic syndrome Brûlé, Sophie Marette, André* 2004/07 - mTOR and insulin resistance Charbonneau, Alexandre Marette, André* Bachelard, Hélène 2006/01 - Rôle de iNOS dans le développement de la résistance à l’insuline Chen, Lingyun Subirade, Muriel* 2003/10 - Development of nanomaterials from food biopolymers Dabour, Nassra LaPointe, Gisèle* Fliss, Ismail 2005/09 - Développement d’une puce à ADN pour Lactococcus cremoris Dao, Huy-Hao Marette, André* 2004/07 - iNOS and insulin resistance Delcenserie, Véronique Roy, Denis* 2006/01 - Méthode de typage des bifidobactéries Diouf, Papa Niokhor Stevanovic, Tatjana* 2005/01 - Extraction ultrasonique de molécules lipophiles de deux espèces de la forêt boréale Labrie, Steve Roy, Denis* LaPointe, Gisèle 2004/06 - Métagénomique alimentaire Laneuville, Sandra Turgeon, Sylvie* Gauthier, Sylvie F. 2005/01 - Fonctionnalité des complexes peptides-polysaccharides Ligeret, Heidi Haddad, Pierre Sélim* 2004/09 - Étude des effets bénéfiques potentiels de la curcumine et de ses dérivés lors de l’ischémie-reperfusion du foie Lochard, N Levy, Emile Haim 2006/05 - - Maillot, Geneviève Levy, Emile Haim 2006/05 - Modulation of intestinal calcium uptake and transport by transcription factors: implication for bone calcification Martineau, Louis Haddad, Pierre Sélim* 2004/01 - Évaluation scientifique rigoureuse de plantes réputées anti-diabétiques Montoni, Alicia Gauthier, Sylvie F.* Pouliot, Yves 2005/05 - Mise au point de méthodes pour la quantification des facteurs de croissance dans des substrats laitiers Montoudis, Alain Levy, Emile Haim* 2004/06 - Role of proteasome in apolipoprotein B processing and intestinal lipid transport Ngazoa, Solange Jean, Julie* 2005/05 - Développement de systèmes d’amplification en temps réel pour la détection des virus entériques Roufik, Samira Gauthier, Sylvie F.* Pouliot, Yves 2005/10 - Caractérisation physico-chimique d’extraits de facteurs de croissance du lait Ruzzin, Jérôme Marette, André* 2006/01 - Fish nutrients and insulin resistance Sane, Alain Théophile Levy, Emile Haim* 2004/09 - Regulation of Niemann-Pick C1 impacts on intestinal lipid transport Vidot, Hélène Cloutier, Martin* 2005/06 - - Zhao, Hailin Jones, Peter* 2005/04 - Plant sterol and cholesterol absorption in individuals with and without coronary heart disease * Main research director 56 New projects A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 INAF Postdoctoral fellows Students Directors P ROJ ECTS CO M P L E T E D I N 20 0 5 -20 0 6 Starting date Finish date Project title Cardinault, Nicolas Thivierge, Carole 2004/11 2005/12 Contrôle de la stéatose hépatique Dadach, Zin-Eddine Arul, Joseph* Belkacemi, Khaled 2003/03 2005/07 Concentration de la matière grasse laitière enrichie en ALC par cristallisation et distillation Dautremepuits, Claire Ramassamy, Charles 2004/09 2005/08 Impact de la consommation de tributhylétin sur les marqueurs d’oxydation cérébraux Demonty, Isabelle Jones, Peter* 2001/01 2005/09 Composition of plant sterols affects plasma lipid response Eymard, Sylvie Arul, Joseph* Belkacemi, Khaled 2004/06 2005/08 Concentration de la matière grasse oméga-3 issue de l’huile de phoque par cristallisation Garon, Sandrine Turgeon, Sylvie* 2005/01 2006/05 Production d’oligosaccharides des fucanes d’Ascophillum et Fucus Genovese, Diego Ratti, Cristina* 2005/04 2005/09 Rhéologie des mousses Maupas-Schwalm, Françoise Levy, Emile Haim* 2004/08 2005/08 Implication du stress oxydant dans l’expression et la signalisation d’uPA/uPAR dans les cellules cancéreuses Remondetto, E. Gabriel Subirade, Muriel* 2003/09 2005/12 Développement et caractérisation de matériaux pour la protection de molécules actives Doctoral students P ROJ ECTS I N P RO G R ESS Students Directors Starting date Finish date Project title AbuMweis, Suhad Jones, Peter* 2003/07 - Plant sterol composition affects plasma lipid levels Aider, Mohammed Bazinet, Laurent* Matescu, A.M. 2004/05 - Électroséparation des oligomères de chitosane Al-Akoum, Mahéra Dodin, Sylvie* 2006/05 Alfonso-Gonzalez, Gisell Tremblay, Angelo* 2000/09 - Étude des effets de l’exercice et de la nutrition sur l’équilibre énergétique et macronutritionnel Audy, Julie LaPointe, Gisèle* Roy, Denis 2003/05 - Quantification de l’expression de gènes chez Bifidobacterium longum Badr, Ashraf Desjardins, Yves* Angers, Paul 2001/08 - Étude des mécanisme d’assimilation du carbone chez la pomme de terre in vitro par métabolomique Badri, Amine Michaud, Dominique* 2003/04 - Translocation intracellulaire différentielle d’inhibiteurs de protéases recombinants chez la pomme de terre Bédie, Gérard Kouadio Turgeon, Sylvie* Makhlouf, Joseph 2003/09 - Microencapsulation de composés nutraceutiques dans les complexes protéines-polysaccharides adaptés à un système alimentaire de type jus de fruits Ben Ounis, Wassef Gauthier, Sylvie F.* Turgeon, Sylvie 2005/01 - Interactions moléculaires pour l’extraction de facteurs de croissance Benabbou, Rajaa Fliss, Ismail* Subirade, Muriel 2003/09 - Mécanisme d’action de biofilms antimicrobiens Benchabane, Meriem Michaud, Dominique* 2002/09 - Mutagenèse et glycolysation des serpines en système d’expression hétérologue Benhaddou-Andaloussi, Ali Haddad, Pierre Sélim* 2005/09 - Études du potentiel anti-diabétique des extraits de Nigella sativa Bertrand, Marie-Eve Turgeon, Sylvie* St-Gelais, Daniel 2003/09 - Développement de nouveaux ingrédients fonctionnels en mélange avec les polysaccharides Blackburn, Patricia Lamarche, Benoît 2003/01 - Impact of exercise on LDL size and other CVD risk factors Bouchiba, Souad Angers, Paul* 2003/09 - Chimie des produits naturels : valorisation des plantes médicinales du Québec * Main research director Millepertuis et symptômes de ménopause chez les femmes ayant souffert d’un cancer du sein New projects 57 INAF A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 Doctoral students P ROJ ECTS I N P RO G R ESS Students Directors Starting date Finish date Project title Bourgoin, Frédéric Bachelard, Hélène* 2005/12 - Role of endothelial NO in vascular and metabolic dysfunction in insulin resistance Brisson, Guillaume Pouliot, Yves* Britten, Michel 2000/09 - Fractionnement de la lactoferrine du lactosérum par électrofiltration Caillard, Romain Subirade, Muriel* 2004/09 - Mécanismes de réticulation d’hydrogels protéiques et impact sur les propriétés de libération d’actifs Carrier, Nathalie West, Gale* 2000/09 Casadémont, Christophe Bazinet, Laurent* 2005/02 - Colmatage des membranes en électrodialyse Chaput, Jean-Philippe Tremblay, Angelo* 2004/09 - Exercise, nutrition and the insulin resistance syndrome. Charbonneau, Édith Chouinard, Yvan 2003/05 - Production de fourrages adaptés à l’alimentation de la vache tarie Choi, Sang-Hyeon Angers, Paul* Arul, Joseph 1999/09 - Fractionnement et physico-chimie des graisses Chouchane, Zahira Roy, Denis* 2003/09 - Probiotiques et prébiotiques - activité et efficacité lors de leur transit dans le tractus digestif Dachet, Fabien LaPointe, Gisèle* Roy, Denis 2004/05 - Analyse de l’activité du microbiote du lait durant la transformation Dagry, Monique Arul, Joseph* Tweddell, Russell 1997/08 - Interactions chitosane-bactéries Dallaire, Patrice Marette, André* 2001/05 - iNOS and insulin resistance Desroches, Sophie Lamarche, Benoît* Lemieux, Simone 2003/05 - Functional nutrition and lipoprotein metabolism Dolley, Guillaume Vohl, Marie-Claude* 2005/10 - Genetics of the small, dense LDL phenotype Doyon, Audrey Chouinard, Yvan* 2002/09 - Modification du profil en acides gras du lait via l’alimentation chez la chèvre Dufresne, Alexandra Dodin, Sylvie* 2006/05 Émile-Nicoué, Eugène Belkacemi, Khaled* Arul, Joseph 2004/09 - Caractérisation chimique des antocyanes des bleuets et investigation sur leur action anti-oxydative Fattouma, Ahmed Taleb Dorais, Martine* 2001/10 - Effet du régime de température sur la répartition des hydrates de carbone et la qualité de la tomate de serre Ferland, Annie Lemieux, Simone 2003/09 - Carbohydrate intake and physical activity in type 2 diabetic subjects Ferraroni Aguiar, Vivian Jones, Peter 2004/09 - Cholesterol metabolism and genetic heterogenecity Gagnon, Mélanie Fliss, Ismail* Jean, Julie 2002/09 - Étude du potentiel des bifidobactéries humaines dans la prévention des infections entériques bactérienne et virale Gervais, Rachel Chouinard, Yvan* 2000/09 - Effets des acides linoléiques et linoléniques conjugués sur la production et la composition du lait chez la vache Goulet, Charles Michaud, Dominique* 2003/05 - Effets pléïotropiques d’anti-cathepsines recombinantes chez la pomme de terre transgénique Goulet, Julie Lemieux, Simone* Lamarche, Benoît 2002/09 - Diète méditerranéenne au Québec Hébert, Claire Desjardins, Yves* 1998/07 - Évaluation des potentiels antioxydants comme indice de la conservation des fraises Hogue, Jean-Charles Couture, Patrick* Lamarche, Benoît 2002/05 - Cardiovascular effects of n-3 PUFAs in dyslipidemic HIV-infected patients Huu, Thuan Bui Ratti, Cristina* Makhlouf, Joseph 2003/01 - Effet de la déshydratation osmotique sur la préservation du lycopène Jean-Denis, Farrah Tremblay, Angelo* 2003/01 - La taille des portions et la densité énergétique des aliments... * Main research director 58 New projects Relations entre des caractéristiques institutionnelles, le risque de malnutrition et la qualité de vie des personnes âgées hébergées Mise en place d’un essai clinique randomisé évaluant l’impact de la relaxation hypnotique sur l’anxiété et le stress A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 INAF Doctoral students Students P ROJ ECTS I N P RO G R ESS Directors Starting date Finish date Project title Kemache, Nassima Belkacemi, Khaled* Arul, Joseph 2006/03 - Hydrogenation of vegetable oils/Novel catalysts Khalf, Mustafa Fliss, Ismail* Michaud, Dominique 2002/01 - Digestibilité et allergénicité de l’inhibiteur de protéases CDI de tomate exprimé chez la pomme de terre Kim, Kyung-Tae Turgeon, Sylvie* 2003/09 - Extraction et caractérisation de molécules bioactives des algues brunes Lachkar, David Pouliot, Yves* 2004/08 - Fractionnement des facteurs de croissance du colostrum bovin Lacroix, Nadine Vuillemard, Jean-Christophe* St-Gelais, Daniel 2003/09 - Caractérisation des activités biologiques et du potentiel technologique de souches bactériennes isolées de ferments lactiques naturels Lamhoujeb, Safaa Jean, Julie* 2004/05 - Caractérisation moléculaire et épidémiologique des toxi-infections à norovirus Lapointe, Annie Lemieux, Simone* 2005/09 - Weight management in postmenopausal women Lavigne, Charles Marette, André* 1997/09 - Effets de la nature des protéines alimentaires sur la prévention de la résistance à l’insuline chez le rat Leclerc, Pierre-Louis Subirade, Muriel* Ramassamy, Charles 2003/05 - Étude le stabilité des nanoparticules à base de protéines Leduc, Geneviève Dodin, Sylvie 2004/09 - Impact d’une intervention intégrée en santé chez des enfants du premier cycle du primaire : éducation à la nutrition, activité physique et gestion du stress Leysi-Derilou, Younes Arul, Joseph* 2004/09 - Production du chitosane par procédé sonochimique Lin Teng Shee, Fabrice Bazinet, Laurent* Arul, Joseph 2004/05 - Solubilisation du chitosane/électro-acidification Lizdaoui, Aziza Stevanovic, Tatjana* 2004/05 - Extractibles de l’écorce du peuplier faux-tremble et de l’épinette noire Lolavic, A Levy, Emile Haim 2002/09 - Cholesterol content in brain of suicide completers Lucas, Michel Dodin, Sylvie* 2003/09 - Essai clinique randomisé, à double-insu, contrôlé pour vérifier l’efficacité d’une supplémentation en acides gras oméga-3 d’origine marine dans le trait. des troubles émotionnels chez des femmes 40-55 ans Major, Geneviève Tremblay, Angelo* 2004/01 - Déterminants de l’obésité humaine... Maltais, Anne Subirade, Muriel* 2003/08 - Étude des mécanismes de formation de gels à froid de protéines de soja et propriétés Marc, Isabelle Dodin, Sylvie* 2003/09 Marcil, Valérie Levy, Emile Haim* 2002/01 - Localisation, rôle et régulation des protéines SR-BI, ABC1 et cavéoline-1 dans le transport et le métabolisme du cholestérol par l’entérocyte Mauger, Jean-François Lamarche, Benoît* 2004/05 - Étude du métabolisme in vivo des LDL de petite taille et du CRP dans le contexte du syndrome métabolique Mercure, Sarah-Amélie Michaud, Dominique* 2006/01 - Réponses aux stress chez des lignées végétales transgéniques à métabolisme protéique altéré Millette, Mathieu Lacroix, Monique* 2002/01 - Bactéries probiotiques et santé humaine Mohamed Mahmoud Eid, Hoda Haddad, Pierre Sélim* 2006/05 - Antidiabetic activity of Cree antidiabetic plants Morin, Pierre Pouliot, Yves* 2002/05 - On the fractionation of buttermilk by microfiltration membranes Moroni, Olivier Fliss, Ismail* Boutin, Yvan 2002/01 - Étude de l’impact sur l’écosystème intestinal de souches de bifidobactéries Nabil, Samira Gauthier, Sylvie F.* 2005/05 - Digestibilité d’un extrait de facteur laitier enrichi en facteurs de croissance Naghmouchi, Karim Fliss, Ismail* 2003/01 - Mécanisme d’action de la divergicine M35 Nicolas, Guillaume LaPointe, Gisèle 2005/01 - Carctérisation biochimique et génétique de nouvelles mutacines Noiseux, Isabelle Gauthier, Sylvie F.* Turgeon, Sylvie 1999/01 - Étude des interactions ß-lactoglobuline/peptide * Main research director Bénéfices de l’analgésie non pharmacologique par l’hypnose pour contrôler la douleur lors de l’interruption volontaire de grossesse : essai clinique New projects 59 INAF A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 Doctoral students P ROJ ECTS I N P RO G R ESS Students Directors Starting date Finish date Project title Ntimbane, Thierry Levy, Emile Haim 2003/09 - Oxidative stress and mitochondrial function Ouellet, Véronique Jacques, Hélène* 2006/01 - Dietary cod protein in insulin-resistant subjects Paradis, Ann-Marie Vohl, Marie-Claude* 2004/09 - Dietary patterns and susceptibility to obesity Paradis, Marie-Eve Lamarche, Benoît* Couture, Patrick 2000/05 - Role of EL in lipoprotein metabolism Pedneault, Karine Tweddell, Russell* Angers, Paul, Gosselin, André 2002/01 - Potentiel nutraceutique des champignons du Québec Peretti, Noël Levy, Emile Haim* 2004/09 - Membrane lipid domain of scavenger receptor B-I and its role in intestinal lipid transport Piché, Marie-Ève Lemieux, Simone* 2002/01 - Cinétique des TG chez la femme ménopausée Pigeon, Étienne Tremblay, Angelo 2005/01 - Phénotypes musculaires associés à la résistance à l’insuline Pilon, Geneviève Marette, André* 1998/09 - iNOS regulation in muscle Preynat, Aurélie Thivierge, Carole* 2004/11 - Effet de l’acide folique et de la vitamine B12 sur le métabolisme et les performances des vaches en début de lactation Provencher, Véronique Lemieux, Simone* 2002/09 - Nouveau paradigme en matière de gestion de poids Raharitsifa, Narindra Ratti, Cristina* 2003/09 - Lyophilisation des produits nutraceutiques par moussage Rasolofo, Éric Roy, Denis* LaPointe, Gisèle 2004/09 - Microflore d’altération du lait Reid, Alexandra Vuillemard, Jean-Christophe* 2002/09 - Enrichissement de jus de fruits par des composés nutraceutiques encapsulés Rioux, Laurie-Eve Turgeon, Sylvie* 2005/05 - Extraction, caractérisation et activité biologique des polysaccharides de Laminaria longicruris Robitaille, Julie Vohl, Marie-Claude* Lemieux, Simone 2002/09 - Influence des effets d’interactions gène-diète sur le profil de risque cardiovasculaire Rudkowska, Iwona Jones, Peter* 2004/05 - Functional oil and energetics in humans Ruel, Guillaume Couillard, Charles* 2005/09 - Role of PUFA and flavonoids in the regulation of oxidative stress, endothelial function and inflammation Rusu, Daniel Gauthier, Sylvie F. 2005/05 - Propriétés anti-inflammatoires d’une extrait laitier enrichi en facteur de croissance Santosa, Sylvia Jones, Peter* 2002/08 - Weight loss and cholesterol metabolism Schreyer, Arnaud Bazinet, Laurent* 2003/09 - Étude de l’impact de la modulation du potentiel redox du lait par électrolyse Spoor, Danielle Haddad, Pierre Sélim* 2003/10 - Évaluation in vivo et in vitro de l’activité anti-diabétique de plantes utilisées par la Nation Cri du Québec St-Sauveur, Diane Gauthier, Sylvie F.* Boutin, Yvan 2004/01 - Propriétés immmunomodulantes des protéines de lactosérum Tahiri, Imane Fliss, Ismail* 2002/09 - Bactériocines de bactéries lactiques d’origine marine Taibi, Amel LaPointe, Gisèle* 2005/09 - L’analyse différentielle de l’expression de gènes chez Lactococcus spp. Tremblay, André Couture, Patrick* Lamarche, Benoît 2002/05 - Étude du métabolisme des lipoprotéines dans diverses dyslipidémies Tremblay, Sébastien Cunnane, Stephen* 2004/07 - Brain metabolism, nutrition and aging Varady, Krista Jones, Peter* 2002/07 - Effect of phytosterols & exercise on cholesterol metabolism Vasanthi Joseph, Shama Jacques, Hélène* 2005/09 - Différents isomères d’ALC et réponse lipidique et inflammatoire Vuong, Tri Haddad, Pierre Sélim* Ramassamy, Charles 2004/09 - Étude de l’effet de la fermentation sur l’activité biologique du jus de bleuet * Main research director 60 New projects A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 INAF Doctoral students Students P ROJ ECTS I N P RO G R ESS Directors Starting date Finish date Project title Amrouche, Tahar Fliss, Ismail* Boutin, Yvan 2000/09 2005/07 Contribution à l’étude du pouvoir immunomodulateur des bifidobactéries : analyse in vitro et étude ex vivo des mécanismes moléculaires impliqués Cinquin, Cécile Françoise Fliss, Ismail 2001/01 2005/07 Développement et validation d’un nouveau modèle de fermentation colique in vitro avec cellules immobilisées Dabour, Nassra LaPointe, Gisèle* Fliss, Ismail 1999/06 2005/07 Exopolysaccharides produced by Lactococcus lactis subsp. cremoris: from genetics to cheese application. Juneau, Christina Pouliot, Yves* Gauthier, Sylvie F. 1999/09 2005/07 Développement d’un composé nutraceutique inhibiteur d’angiogénèse à partir de cartilage d’élasmobranche Lavoie, Jean-Michel Stevanovic, Tatjana* 2001/05 2005/12 Optimisation de l’extraction des triterpènes par ultrason et identification du contenu moléculaire libre des tissus de bouleau jaune (Betula alleghaniensis) Pacheco-Sanchez, Maribel Tweddell, Russell* Boutin, Yvan, Gosselin, André 2001/09 2006/05 Polysaccharides fongiques et activité immunomodulante Plourde, Mélanie Angers, Paul* 2003/05 2006/04 Étude des effets physiologiques des acides alpha-linoléniques conjugués Roufik, Samira Gauthier, Sylvie F.* Turgeon, Sylvie 2000/09 2005/10 Étude des interactions ß-Lactoglobuline bovine : peptides bioactifs et digestibilité in vitro des complexes Samane, Samira Haddad, Pierre Sélim 2003/09 2005/09 Études des propriétés biologiques de l’huile d’argan Masters students P ROJ ECTS I N P RO G R ESS Students Directors Starting date Finish date Project title Akbache, Abderrazak Pouliot, Yves* 2005/01 - Effet des caractéristiques du lactosérum sur son contenu en facteurs de croissance Badeau, Mylène Bachelard, Hélène* 2003/01 - Effect of a long term treatment with tempol on metabolic and vascular actions of insulin in a rat model with insulin resistance and obesity. Bégin, Michel Cunnane, Stephen* 2006/03 - Iodine metabolism during aging Bélanger, Caroline Tremblay, Angelo* 2005/09 - Relations familiales et obésité Ben Djoudi Ouadda, Ali Levy, Emile Haim 2006/01 - - Biette, Frédéric Subirade, Muriel 2006/05 - Étude des réseaux interpénétrés protéine-amylose Blain-Fortin, Marianne Roy, Denis* LaPointe, Gisèle 2005/09 - Banque métagénomique Blanchette, Rosanne Lemieux, Simone 2006/05 - Nutrigénomique Boucher, Marie-Christine Makhlouf, Joseph* Turgeon, Sylvie 2004/09 - Stabilité des complexes ß-globuline-pectine dans le jus de pomme Bouffard, Marie-Claude Subirade, Muriel* 2004/08 - Étude des protéines de mais : caractérisation et application comme excipient dans des formulations orales Boukadida, Rida Arul, Joseph* 2005/01 - UV stress responses in tomato fruit Boutin, Denis Chouinard, Yvan 2002/01 - Produire du lait en tout ensilage Brodeur, Vincent Pothier, François* 2003/05 - Polymorphismes de la leptine Cakmak, Zaliha Gauthier, Sylvie F.* Pouliot, Yves 2005/09 - Protection de l’activité biologique par des interactions peptide/protéine Caron-Dorval, Dominique Vohl, Marie-Claude* 2006/01 - Gene-diet interactions Casapciuc, Nadia Angers, Paul* Arul, Joseph 2004/09 - Formation of cyclic fatty acid monomers in frying oils * Main research director New projects 61 INAF A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 Masters students P ROJ ECTS I N P RO G R ESS Students Directors Starting date Finish date Project title Centeno-Baez, Carolina Marette, André* 2006/01 - iNOS and insulin resistance Chan, Yen Ming Jones, Peter* 2003/09 - The effect of fatty acid composition of plant sterol esters on blood lipid profiles and plasma plant sterol levels in hypercholesterolemic subjects Chay Pak Ting, Bertrand Pouliot, Yves* Gauthier, Sylvie F. 2005/09 - Nanofiltration d’un hydrolysat trysique de ß-lactoglobuline Chenavas, Françoise Saives, Anne-Laure* Cloutier, Martin 2004/09 - Territorialisation des processus clés des entreprises des secteurs aliments fonctionnels et nutraceutiques Collins, Melissa Jones, Peter* 2002/09 - Effect of phytosterols & exercise on cholesterol metabolism Coulibaly, Estelle Angers, Paul* 2003/09 - Détection de gras végétaux dans le chocolat Curt, Séverine Subirade, Muriel 2006/01 - Étude biologique de biofilms protéiques Danh, Huynh Ramassamy, Charles* 2006/05 - Structure-activity of polyphenol and neuroprotection Dia, Rouguiatou Makhlouf, Joseph* Ratti, Cristina 2006/01 - Caractérisation nutraceutique du fruit de l’argousier frais et séché Diaz, Éduardo Thivierge, Carole* 2004/05 - Effet de différents additifs au maïs-épi humide sur sa conservation et les performances de finition des bouvillons Dostaler-Touchette, Valérie Chouinard, Yvan* 2006/05 - Stratégie nutraceutique pour l’amélioration de la production laitière par le contrôle enzymatique des phosphodiestérases de la glande mammaire Driss, Lkassbi West, Gale* 2004/08 - Déterminants de l’intention d’achat des AFN : oméga-3 et lycopène Dubuc, Jean-Francois Desjardins, Yves* 2003/05 - Étude de l’expression génique de plantes in vitro cultivées sous des conditions contrastantes de l’environnement par microarray Dufour-Bouchard, Andrée-Ann Lemieux, Simone* 2005/09 - Comportements alimentaires chez les femmes avec surplus de poids Dumont, Geneviève Couture, Patrick* 2006/01 - Cardiovascular impact of n-3 polyunsaturated fatty acids in HIV dyslipidemic patients Dussault, Dominic Lacroix, Monique* 2006/05 - Radiorésistance bactérienne Fall, Maina West, Gale* 2006/01 - Déterminants d’achat des aliments fonctionnels Faucher, Jean-Philippe Chouinard, Yvan* 2001/09 - Développement d’un lait santé naturellement enrichi en acides linoléiques conjugués. Phase II - Étude économique Filteau, Marie Roy, Denis* 2005/09 - Métagénomique sève d’érable Freemantle, Erika Cunnane, Stephen* 2005/02 - Energy metabolism during aging Gagnon, Josée Lamarche, Benoît* 2005/01 - Impact du lait sur les facteurs de risque du syndrome métabolique Garcia Perez, Martha Estrella Stevanovic, Tatjana* 2005/05 - Étude des composés phénoliques extraits de tissus de bouleau jaune (Betula alleghaniensis) Gayraud, Hélène West, Gale 2001/01 - Messages et contenu des publicités imprimées de suppléments nutritionnels, aliments fonctionnels, et nutraceutiques s’adressant aux personnes âgées du Québec Gentes, Marie-Claude Turgeon, Sylvie* St-Gelais, Daniel 2005/01 - Fonctionnalité des complexes protéines-PS dans les yogourts Gigleux, Iris Lamarche, Benoît* Couture, Patrick 2005/01 - Impact of the portfolio diet in hypercholesterolemic subjects Girard, Maryline Jean, Julie* 2006/05 - Transmission et interruption des norovirus aux aliments Goulet, Marie-Claire Michaud, Dominique* 2004/09 - Mutagénèse dirigée des cystatines végétales Grenier, Émilie Levy, Emile Haim* 2005/01 - Role of retinoic acid in cell differentiation and function: impact on HDL synthesis Grignon, Louis Fliss, Ismail 2001/01 - Optimisation de la production de nisine Z par cellules immobilisées et immunoaffinité * Main research director 62 New projects A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 INAF Masters students P ROJ ECTS I N P RO G R ESS Students Directors Starting date Finish date Project title Gutierrez, Luis Felipe Belkacemi, Khaled* Ratti, Cristina 2005/01 - Extraction des huiles des fruits d’argousier du Québec Haratifar, Sanaz Angers, Paul* Britten, Michel 2004/09 - Stabilité du lait électro-réduit Harbilas, Despina Haddad, Pierre Sélim* 2005/09 - Antidiabetic potential of plant from the Cree Nation of Whapmaghoosti Hermanilla, Illiana Turgeon, Sylvie* 2004/09 - Systèmes mixtes gélifiés protéines-chitosane Houweling, Adrielle Jones, Peter* 2005/06 - Plant sterol and cholesterol absorption in individuals with and without coronary heart disease Jacob, Aglaée Couillard, Charles* 2006/01 - Dietary macronutrients, glycemic index and lipoprotein oxidation in men with CHD Jacquot, Arnaud Gauthier, Sylvie F.* 2005/09 - Effet des interactions peptide/peptide sur leur propriétés immunomodulantes de peptides bioactifs Jain, Deepak Jones, Peter* 2004/05 - Effect of corn fibre oil and its constituents on cholesterol metabolism and intestinal steroltransporter gene expression in hamsters Jedidi, Hajer Fliss, Ismail* 2005/01 - Effet du stress gastrointestinal sur la production de bactériocines chez les bactéries lactiques Kassis, Amira Jones, Peter* 2004/09 - Policosanols as cholesterol lowering agents Lake, Jennifer Robert, Claude 2004/06 - Impact de différents traitements alimentaires sur l’expression génétique de tissus cibles chez la truite Lalonde, Geneviève Levy, Emile Haim* 2006/01 - Lipid transport in Psammomys obesus, a model for insulin resistance and type 2 diabetes Latulippe, Carl Thivierge, Carole* Chouinard, Yvan 2005/01 - The interaction between marine n-3 and leucine in the regulation of protein metabolism in growing steers Le Dévédec, Frantz Bazinet, Laurent 2005/01 - Caractérisation physico-chimique de chitosane Lebbar, Abdelhaq Belkacemi, Khaled* 2002/09 - Production de pigment alimentaire : astaxanthine par fermentation du sirop d’érable déclassé Leblonc, François Levy, Emile Haim* 2006/01 - Sinergetic role of SR-BI and NPC1L1 in cholesterol transport Leduc, Charles Haddad, Pierre Sélim* 2003/09 - Étude scientifque rigoureuse des plantes antidiabétiques utilisées par la nation Cri du Québec Le Lay, Christophe Fliss, Ismail* 2005/09 - Activité antifongique des bactériocines de bactéries lactiques Lessard, Jocelyn Vuillemard, Jean-Christophe* St-Gelais, Daniel 2004/09 - Caractérisation des activités biologiques et du potentiel technologique de souches bactériennes isolées de ferments lactiques naturels Lessard, Marie-Hélène LaPointe, Gisèle* Roy, Denis 2005/09 - Génomotypage comparatif des sous-espèces de Lactococcus Leung, Valérie Subirade, Muriel* 2002/08 - Modulation des propriétés des anti-oxydantes par des matrices protéiques Levesque, Josée Lamarche, Benoît* 2006/05 - Étude du métabolisme in vivo de la protéine C-réactive (CRP) en réponse à un traitement pharmacologique Lkassbi, Driss West, Gale 2003/09 Loufrani, Samson Saives, Anne-Laure* 2004/09 - Coordination d’activités : alliances et collaborations dans le système bio-industriel du Québec Marchut, Joanna Jones, Peter* 2004/09 - Plant sterol and cholesterol absorption in overweight hypercholesterolemic men Marinangeli, Christopher Jones, Peter* Cunnane, Stephen 2004/09 - Policosanols as cholesterol lowering agents Marquis-Duval, Francois Olivier Arul, Joseph* Belkacemi, Khaled 2004/09 - Déproteination et déminéralisation de la carapace de crevette * Main research director Les déterminants de la probabilité d’achat des aliments fonctionnels et des nutraceutiques. Cas du lycopène et d’oméga-3 New projects 63 INAF A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 Masters students P ROJ ECTS I N P RO G R ESS Students Directors Starting date Finish date Project title Marsolais, Jean-François West, Gale 2003/09 - L’intention des médecins généralistes et des diététistes du Québec de recommander les aliments fonctionnels et les nutraceutiques à leurs patients. Martinez-Gonzale, José-Luis Roy, Denis*, LaPointe, Gisèle 2004/09 - Dégradation d’exopolysaccharides Masouleh, Tahreh Tale West, Gale 2003/09 - Les croyances des médecins généralistes et des diététistes de la région de Québec envers les aliments fonctionnels et les nutraceutiques Mercier, Christian Subirade, Muriel* 2006/01 - Nanoemulsion for controlled release of nutraceuticals Moreau, Jean-Guy Stevanovic, Tatjana* 2005/05 - Extraction des molécules bioactives du feuillage de l’if du Canada Motard-Bélanger, Annie Lamarche, Benoît* 2006/01 - Impact des gras trans naturels sur la santé cardiovasculaire Muthukamaran, Arun Ratti, Cristina* 2004/09 - Modélisation de la lyophilisation des mousses Naud, Julie Angers, Paul 2004/06 - Molécules bioactives dans différentes populations de plantes médicinales du Québec Ndiaye, Mamadou Mansour West, Gale 2004/08 - Demande de poissons et produits marins au Canada Ouellet, Véronique Jacques, Hélène* 2004/01 - Protéine de poisson chez des sujets insulino-résistants Paquin, Julie Turgeon, Sylvie* Lemieux, Simone 2004/09 - Effet d’un jus enrichi en fibre sur le profil glycémique Paradis, Cloé Chouinard, Yvan* 2003/05 - Production de veau sous la mère enrichi en acides linoléiques conjugués Payette, Caroline Couillard, Charles* 2005/09 - Impact of PUFA and antioxidants on the postprandial lipemic response of abdominally obese men Perreault, Véronique Britten, Michel* Turgeon, Sylvie 2003/09 - Influence des matrices alimentaires sur la cinétique de libération des composés d’arôme Plamondon, Éveline Saucier, Linda* 2004/09 - Thermorésistance de Mycobacterium avium subsp. paratuberculosis Plourde, Mélanie Belkacemi, Khaled* Arul, Joseph 2001/09 - Hydrogénation des huiles végétales avec une nouvelle génération de catalyseurs Plourde, Nathalie Chouinard, Yvan* 2001/09 - Développement d’un lait santé naturellement enrichi en acides linoléiques conjugués. Phase I - Étude de la composition du lait Poulin, Jean-François Bazinet, Laurent* Amiot, Jean 2006/05 - Électroséparation de peptides bio-actifs Poulin, Véronique Chouinard, Yvan* 2005/05 - Effets de l’alimentation et des implants hormonaux sur la qualité de la viande chez le bovin Rachek, Sadjia Roy, Denis* Labrie, Steve 2005/09 - Phylogénétique des fromages Radanielina, Para Angers, Paul* Arul, Joseph 2005/05 - Stabilité thermique et oxidative du gras laitier enrichi en CLA Riou, Marie-Ève Tremblay, Angelo* 2006/01 - Capacité à l’effort et santé métabolique chez les sédentaires Rocafi, Adil Pouliot, Yves* 2006/01 - Précipitation des isolats de protéines de lactosérum Roffey, Ben Jones, Peter* Kubow, Stan 2003/09 - The effects of Momordica charantia and Cinnamon extracts on glucose uptake and adiponectin in 3T3-L1 adipose cells Roy, Sophie Jean, Julie* 2005/09 - Développement d’un système d’immunoconcentration des norovirus dans des échantillons alimentaires Sanchez, Marina Tremblay, Angelo* 2004/09 - Les composés organochlorés dans la nourriture Savard, Patricia Roy, Denis* LaPointe, Gisèle 2004/09 - Prébiotiques Soucy, Juan Pablo Robert, Claude* 2004/09 - Comparaison de la qualité des fibres musculaires entre différentes races de porcs commerciaux Spahis, Schoraya Levy, Emile Haim* 2004/09 - N-3 fatty acids associated to mental health and behavior * Main research director 64 New projects A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 INAF Masters students P ROJ ECTS I N P RO G R ESS Students Directors Starting date Finish date Project title St-Laurent Thibault, Catherine Ramassamy, Charles* 2006/01 - Régulation de l’expression des récepteurs ETa et ETb par le peptide amyloide Thériault, Pierre-Antoine Jean, Julie* 2005/09 - Persistance des norovirus dans les aliments et dans l’eau par les méthodes moléculaires Tian, Zhigang Angers, Paul* Arul, Joseph 2005/01 - Purification omega-3 fatty acids Tousignant, Simon Arul, Joseph* 2005/01 - Conversion of chitin to chitosan Tremblay, Audrey Britten, Michel* 2004/01 - Production d’exopolysaccharide par une souche de S. Thermophilus Gal+ Tremblay-Mercier, Jennifer Cunnane, Stephen* 2006/04 - Fibrates and ketogenesis in the elderly Turcotte, Stéphane Marette, André* 2006/05 - Effets des nutriments de poisson sur l’insulino-résistance Turgeon, Sabrina Tremblay, Angelo* 2006/01 - Évaluation du profil nutritionnel de la personne obèse Turgis, Mélanie Lacroix, Monique* 2005/09 - Radiosensibilisation microbienne Vandal, Mylène Cunnane, Stephen* 2005/12 - Omega-3 fatty acid metabolism during aging Venkatramanan, Sudha Jones, Peter* 2003/08 - Role for milk naturally enriched with conjugated linoleic acid in body weight regulation Viel, Louise-Marie Subirade, Muriel* 2002/08 - Protection de bactéries probiotiques Vlad, Mirela Belkacemi, Khaled* Arul, Joseph 2005/01 - Conversion of lactose to lactobionic acid White, Phill Marette, André 2005/09 - n-3 FFA and insulin resistance Zarrouki, Amal Cloutier, Martin* 2003/01 - Mesure de la performance dans le secteur des NAF Masters students P ROJ ECTS CO M P L E T E D I N 20 0 5 -20 0 6 Students Directors Starting date Finish date Project title Adandé, Sokan Bazinet, Laurent* Makhlouf, Joseph 2003/05 2006/03 Séparation des isoflavones de soja par électrodialyse Ayala-Bribiesca, Erik Bazinet, Laurent* 2003/09 2005/10 Colmatage des membranes par les minéraux et les protéines en cours d’électrodialyse conventionnelle Badeaux, Frédérique LaPointe, Gisèle* 2002/09 2005/09 Étude de l’interaction entre les protéines impliquées dans le complexe de polymérisation des exopolysaccharides chez Lactobacillus rhamnosus Barake, Roula Jones, Peter* 2004/01 2005/10 Effects of plant sterols and glucomannan on parameters of cholesterol kinetics in hyperlipidemic individuals with and without type 2 diabetes Bélanger-Ducharme, Frédérique Tremblay, Angelo* 2003/09 2005/07 Pratique de l’activité physique et qualité de l’alimentation. Une interrelation ? Benchabane, Samir Subirade, Muriel 2003/05 2005/12 Production de microcapsules de phytase par atomisation : influence sur la disponibilité des nutriments chez la truite arc-en-ciel (Oncorhynchus mykiss) Bergeron, Karen Thivierge, Carole* 2003/05 2005/06 Neonatal regulation of muscle protein anabolism in the piglet Bolduc, Marie-Pierre Vuillemard, Jean-Christophe* Champagne, Claude P. 2003/09 2005/12 Effet de la modulation électrochimique du lait sur la flore psychrotrophe native et sur la viabilité de cultures probiotiques ajoutées pendant l’entreposage sous réfrigération Boulmerka, Amira Belkacemi, Khaled* Arul, Joseph 2003/01 2006/04 Hydrogénation catalytique des huiles de tournesol et canola minimisant la production des acides gras trans et saturés : étude des paramètres de procédé Bourgoin, Frédéric Bachelard, Hélène* 2002/09 2006/04 Caractérisation de l’association entre les effets vasculaires et métaboliques de l’insuline chez des rats insulino-résistants et ayant un surplus de poids Bouthillier, Lise Levy, Emile Haim 2003/01 2006/01 Effect of fish oil on clinical and biochemical parameters in Crohn’s disease * Main research director New projects 65 INAF A N N U A L R E P O R T 2 0 0 5 - 2 0 0 6 Masters students P ROJ ECTS CO M P L E T E D I N 20 0 5 -20 0 6 Students Directors Starting date Finish date Project title Casavant, Stéphanie Levy, Emile Haim 2002/09 2005/12 Genetics cholestasis Choi, Sang-Hyeon Angers, Paul* Arul, Joseph 2002/09 2006/03 Milk fat crystallization using a pseudo-solvent Choquette, Anne Vohl, Marie-Claude* 2004/05 2006/01 Rôle du gène upstream transcription factor-1 dans le syndrome métabolique Couture, Audrey Haddad, Pierre Sélim* 2002/09 2005/10 Potentiel antidiabétique du bleuet québécois Vaccinium angustifolia. Durand, Stéphanie Lessard, Martin 2003/09 2005/12 Influence de la graine de lin sur la croissance et l’immunité des porcs sevrés El Ourabi Regaya, Hédia Cloutier, Martin* West, Gale 2003/01 2005/09 L’influence de la confiance dans l’allégation santé, du risque et des bénéfices perçus sur l’intention d’achat des aliments fonctionnels Farrah, Jean-Denis Tremblay, Angelo* 2004/01 2006/01 La taille des portions et la densité énergétique des aliments : ont-elles un rôle à jouer dans la problématique de l’obésité ? Favret, Sandra Marette, André* 2003/01 2006/01 Rôle de iNOS dans la résistance à l’insuline : impact sur un modèle sévère d’obésité et rôle potentiel des macrophages infiltrants du muscle squelettique Filion, Marie-Michèle Britten, Michel* Pouliot, Yves 2003/09 2006/04 Amélioration de la stabilité thermique du lait par modulation du potentiel d’oxydoréduction Gagnon, Diane Champagne, Claude P.* Vuillemard, Jean-Christophe 2003/09 2006/04 Formulation et propagation de ferments lactiques mésophiles à haut caractère aromatique Gingras, Andrée-Anne Thivierge, Carole* Chouinard, Yvan 2003/05 2006/04 Marine n-3 fatty acids improve protein anabolism: an alternative for livestock rearing Lapointe, Annie Lemieux, Simone* Couillard, Charles 2004/01 2005/11 Lipoprotéines de faible densité oxydées : association avec les composantes du syndrome métabolique et effets d’une intervention nutritionnelle visant l’adoption d’une alimentation méditerranéenne Lavoie, Caroline Subirade, Muriel* Angers, Paul 2003/09 2005/12 Élaboration de particules protéiques de taille contrôlée : application à la protection des acides gras oméga-3 contre l’oxydation Longpré, Fanny Ramassamy, Charles* 2003/10 2005/12 Etude de l’interaction entre l’EGb 761 et le petide amyloide Nadeau, Geneviève Couture, Patrick* Lemieux, Simone 2002/05 2005/09 Évaluation des habitudes alimentaires associées à l’hypercholestérolémie familiale Riccioni, Lorenza Ramassamy, Charles* 2004/05 2006/05 Analyse des effets neuroprotecteurs de l’endothéline Rioux, Laurie-Eve Turgeon, Sylvie* 2003/09 2005/09 Caractérisation structurale et rhéologique des polysaccharides des algues brunes Roynette, Catherine Jones, Peter* 2003/09 2005/10 Effect of functional oil on energy expenditure and lipid levels Ruel, Guillaume Couillard, Charles* 2003/09 2006/01 Effets de la supplémentation en antioxydants sur le bilan lipidique : rôle cardioprotecteur du jus de canneberges Seyer, Marie-Ève Turgeon, Sylvie 2003/09 2005/10 Les fibres alimentaires et le pain de blé entier Trudel, Karine Levy, Emile Haim* 2004/01 2005/12 Paraoxonase, as an antioxidant in Crohn’s disease Vaillancourt, Louis-Philippe Michaud, Dominique* 2003/09 2005/11 Effets pléiotropiques d’une forme recombinante de la cystatine II du maïs exprimée dans le cytosol des cellules de pomme de terre Vallée, Karine Tremblay, Angelo* 2003/09 2006/05 Impact d’une activité physique aérobie sur l’équilibre énergétique et les choix alimentaires chez la femme ménopausée présentant une obésité modérée * Main research director 66 New projects Science enhancing nutrition www.inaf.ulaval.ca Institute of Nutraceuticals and Functional Foods Pavillon des Services Université Laval 2440, Hochelaga Blvd. Québec, Québec Canada G1V 0A6 Phone: 418.656.3527 Fax: 418.656.5877 [email protected] www.inaf.ulaval.ca