Personal Information - Montreal Diabetes Research Center

DRAFT
Dr. Jean-Louis Chiasson
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Personal Information
Identification
Dr. Jean-Louis Chiasson
Correspondence language: English
Sex: Male
Date of Birth: 8/25
Canadian Residency Status: Canadian Citizen
Country of Citizenship: Canada
Language Skills
Language
Read
Write
Speak
Understand
English
Yes
Yes
Yes
Yes
French
Yes
Yes
Yes
Yes
Address
The primary address is denoted by (*)
Courier
Primary Affiliation (*)
CRCHUM
Hôtel-Dieu
3850 St. Urbain Street
Masson Pavilion, Rm 8-202
Montréal
H2W 1T7
Canada, Quebec
CRCHUM
Hôtel-Dieu
3850 St. Urbain Street
Masson Pavilion, Rm 8-202
Montréal
H2W 1T7
Canada, Quebec
Telephone
The primary telephone is denoted by (*)
Fax
514-4127208
Work
514-8908000 extension: 12923
Work (*)
514-8908000 extension: 12732
Email
The primary email is denoted by (*)
Work (*)
[email protected]
1
DRAFT
Dr. Jean-Louis Chiasson
User Profile
Disciplines Trained In: Endocrinology
Research Disciplines: Endocrinology
Areas of Research: Diabetes, Hormonal Regulation, Metabolism, Nutrition, Pharmacoepidemiology
Fields of Application: Biomedical Aspects of Human Health, Pathogenesis and Treatment of
Diseases
Research Specialization Keywords: carbohydrate metabolism, complications, diabetes melllitus,
glucagon secretion/action, glucose turnover, insulin secretion/action, isotopic technique, nutrition/
treatment, organ perfusion, prevention
Education
Degrees
1970/7 - 1975/7
Diploma - Certification - Endocrinology - McGill University - Completed
1967/7 - 1968/7
Doctorate - LMCC - M.D. - Endocrinologist - Medical Research Council of
Canada - Completed
1963/9 - 1967/7
Doctorate - M.D. - Medical Doctor - Université Laval - Completed
1961/9 - 1963/7
Bachelor's - B.A. - Chemistry - Sainte-Anne - Completed
Employment
Academic Work Experience
1992/10 -
Chief, Research Group on Diabetes and Metabolic Regulation
CRCHUM
1992/7 -
Full Professor
Université de Montréal - Médecine
1980/7 -
Endocrinologist
CHUM
Affiliations
The primary affiliation is denoted by (*)
(*) 1992/7 -
Full Professor - Médecine - Université de Montréal
Research Funding History
Awarded
2012/5 - 2019/5
Principal
Investigator
The effect of dulaglutide on major cardiovascular events in patients with type
2 diabetes: Researching Cardiovascular Events with a Weekly INcretin in
Diabetes (REWIND).
Principal Investigator : Jean-Louis Chiasson
2
DRAFT
Dr. Jean-Louis Chiasson
Funding Sources
2012/5 - 2019/5 Clinical randomized trial
Eli Lilly Canada Inc.
Total Funding: 266220 (Canadian dollar)
Funding Competitive?: No
2012/6 - 2017/6
Co-applicant
Determinants of increased risk of cardio-vascular diseases in HIV-infected
individuals.
Funding Sources
2012/6 - 2017/6 Subvention d'équipe: VIH/sida et comorbidités
Canadian Institutes of Health Research (CIHR)
Total Funding: 497945 (Canadian dollar)
Funding Competitive?: Yes
2011/4 - 2016/4
Principal
Investigator
Étude de phase IV multicentrique, à répartition aléatoire et à double insu avec
contrôle par placebo visant à évaluer l’effet de la saxagliptine sur l’incidence
du décès d’origine cardiovasculaire, de l’infarctus du myocarde ou de l’AVC
ischémique..
Co-investigator : Sophie Bernard
Funding Sources
2011/4 - 2016/4 AstraZeneca Canada Inc.
Total Funding: 187500 (Canadian dollar)
Funding Competitive?: No
2010/1 - 2015/1
Principal
Investigator
TECOS: A randomized, placebo controlled clinical trial to evaluate
cardiovascular outcomes after treatment with sitagliptin in patients with
type 2 diabetes mellitus and inadequate glycemic control on mono- or dual
combination on oral...
Principal Investigator : Chiasson, Jean-Louis;Étude multicentrique;
Funding Sources
2009/11 Clinical trial
2015/11
Merck & Co. Inc
Total Funding: 320000 (Canadian dollar)
Funding Competitive?: No
2012/5 - 2014/5
Principal
Investigator
The impact of LY2605541 versus insulin glargine for patients with type
1 diabetes mellitus treated with preprandial insulin lispro: a double-blind,
randomized, 52-week study. The IMAGINE 3 Study.
Co-investigator : Sophie Bernard
Funding Sources
2012/5 - 2014/5 Clinical randomized trial
Eli Lilly Canada Inc.
Total Funding: 141552 (Canadian dollar)
Funding Competitive?: No
2011/7 - 2013/7
Principal
Investigator
A 24-week, multicenter, international, randomized (1:1), parallel-group, openlabel, comparative study of insulin glargine versus liraglutide in insulin-naive
patients with type 2 diabetes trated with oral agents and not adequately
controlled with...
Co-investigator : Sophie Bernard
3
DRAFT
Dr. Jean-Louis Chiasson
Funding Sources
2011/7 - 2013/7 Sanofi-aventis
Total Funding: 53450 (Canadian dollar)
Funding Competitive?: No
2012/7 - 2013/6
Quelle est l'évidence justifiant la recommandation d'utiliser 1 mg de glucagon
Principal Applicant pour corriger l'hyperglycémie sévère chez le sujet avec diabète de type 1 ?
Principal Applicant : Jean-Louis Chiasson
Funding Sources
2012/7 - 2013/6 Diabetes Québec
Total Funding: 20000 (Canadian dollar)
Funding Competitive?: Yes
2012/5 - 2013/5
Principal
Investigator
6-month, multicenter, randomized, open-label, parallel-group study comparing
the efficacy and safety of a new formulation of insulin glargine and Lantus both
plus mealtime insulin in patients with type 2 diabetes mellitus with a 6-mo safety
extension
Co-investigator : Sophie Bernard
Funding Sources
2012/5 - 2013/5 Clinical randomized trial
Sanofi-aventis
Total Funding: 58536 (Canadian dollar)
Funding Competitive?: No
2010/3 - 2013/3
Co-applicant
Autogestion du diabète et dépression
Principal Investigator : Marie-Dominique Beaulieu
Funding Sources
2010/3 - 2013/3 Operating grant
Canadian Institutes of Health Research (CIHR)
Total Funding: 232883 (Canadian dollar)
Funding Competitive?: Yes
2011/2 - 2013/2
Principal
Investigator
A randomized, doule-blind, placebo-controlled, parallel-group, multicenter
study to evaluate the efficacy, safety, and tolerability of canagliflozin compared
with placebo in the treatment of older subjects with type 2 diabetes mellitus
inadequately..
Co-investigator : Sophie Bernard
Funding Sources
2011/2 - 2013/2 Clinical trial, Janssen Inc.
Janssen-Ortho Inc.
Total Funding: 94918 (Canadian dollar)
Funding Competitive?: No
2011/4 - 2012/4
Principal
Investigator
A phase III double-blind, extension, placebo-controlled parallel group safety and
efficacy trial of BI 10773 (10 mg and 25 mg once daily) and sitagliptin (100 mg
once daily) given for a minimum of 76 weeks (incl. 24 weeks of preceding trial)...
Co-investigator : Sophie Bernard
4
DRAFT
Dr. Jean-Louis Chiasson
Funding Sources
2011/4 - 2012/6 Clinical trial, Boehringer Ingelheim
Boehringer Ingelheim
Total Funding: 52814 (Canadian dollar)
Funding Competitive?: No
2010/1 - 2011/1
Co-applicant
VIH et prévention des comorbidités: Adapter et valider une intervention virtuelle
visant à réduire les facteurs de risque liés aux maladies cardiovasculaires et au
diabète chez les personnes vivant avec le VIH.
Principal Investigator : Josée Coté
Funding Sources
2010/1 - 2011/1 Operating grant
Canadian Institutes of Health Research (CIHR)
Total Funding: 99956 (Canadian dollar)
Funding Competitive?: Yes
Completed
2011/1 - 2012/1
Co-applicant
A randomized trial evaluating the effect of liraglutide versus insulin glargine on
hepatic steatosis as measured by MRI and MRS in metformin-treated patients
with type 2 diabetes.
Principal Investigator : An Tang
Funding Sources
2010/1 - 2011/1 RSNA R&E Foundation
Fonds de la Recherche en Santé du Québec (FRSQ)
Total Funding: 47500 (Canadian dollar)
Funding Competitive?: Yes
2007/7 - 2011/7
Co-applicant
Rigorous evaluation and integration medicine in aboriginal diabetes care.
Principal Investigator : Pierre Haddad
Funding Sources
2007/7 - 2011/7 Team in Traditional Aboriginal Plants Against Diabetes
Canadian Institutes of Health Research (CIHR)
Total Funding: 850000 (Canadian dollar)
Funding Competitive?: Yes
2010/9 - 2011/3
Principal
Investigator
A phase III randomised, double-blind, placebo-controlled, parallel group,
efficacy and safety study of BI 10773 (10 mg, 25 mg) administered orally, once
daily over 24 weeks in patients with type 2 diabetes mellitus with insufficient
glycemic control.
Co-investigator : Sophie Bernard
Funding Sources
2010/9 - 2011/3 Clinical trial, Boehringer Ingelheim
Boehringer Ingelheim
Total Funding: 52814 (Canadian dollar)
Funding Competitive?: No
2010/1 - 2011/1
Co-applicant
Essai randomisé du liraglutide versus l'insuline glargine sur la stéatose
hépatique...
Principal Investigator : An Tang
5
DRAFT
Dr. Jean-Louis Chiasson
Funding Sources
2010/1 - 2011/1 Diabetes Québec
Total Funding: 20000 (Canadian dollar)
Funding Competitive?: Yes
2010/1 - 2011/1
Co-applicant
Essai randomisé du liraglutide versus l'insuline glargine sur la stéatose
hépatique mesurée par résonance magnétique chez les patients atteints de
diabète de type 2 traités à la metformine.
Principal Investigator : Tang, An;Dr Jean-Louis Chiasson
Funding Sources
2010/1 - 2011/1 Canadian Heads of Academic Radiology (CHAR)
Total Funding: 7500 (Canadian dollar)
Funding Competitive?: Yes
2007/7 - 2010/7
Co-applicant
Estimating the prevalence of diabetes using multiple tests: A validation of the
national diabetes surveillance system definition.
Principal Investigator : Elham Rahme
Funding Sources
2007/7 - 2010/7 INMD Diabetes Surveillance Systems/CIHR
Canadian Institutes of Health Research (CIHR)
Total Funding: 299999 (Canadian dollar)
Funding Competitive?: Yes
2009/1 - 2010/1
Co-applicant
Innovation in cardiovascular imaging and image-guided therapy to improve
patient management.
Principal Investigator : Gilles Soulez
Funding Sources
2009/1 - 2010/1 FCI 20974
Canada Foundation for Innovation (CFI)
Total Funding: 1199774 (Canadian dollar)
Funding Competitive?: Yes
2007/7 - 2009/7
Co-applicant
The DREAM On Study (an observational study). Diabetes REduction
Assessment with ramipril and rosiglitazone Medication Ongoing evaluation.
Principal Investigator : Hertzel C. Gerstein
Funding Sources
2007/7 - 2008/7 Clinical Trial
Canadian Institutes of Health Research (CIHR)
Total Funding: 13500 (Canadian dollar)
Funding Competitive?: No
2007/6 - 2008/12
Principal
Investigator
A multicenter, randomized, double-blind study to evaluate the safety and
efficacy of the addition of sitagliptin (MK-0431) to patients with type 2 diabetes
mellitus who have inadequate glycemic control on insulin therapy (alone or in
combination...
Co-investigator : Rémi Rabasa-Lhoret
Funding Sources
2007/6 - 2008/12 Merck Frosst Canada Inc
Total Funding: 52312 (Canadian dollar)
Funding Competitive?: No
6
DRAFT
Dr. Jean-Louis Chiasson
2007/11 - 2008/11 A 12-week, randomized, multicenter, double-blind, placebo-controlled study,
Principal
assessing the safety and efficacy of ID1101 in obese patients
Investigator
Co-investigator : Rémi Rabasa-Lhoret
Funding Sources
2007/11 Innodia Inc.
2008/11
Total Funding: 62520 (Canadian dollar)
Funding Competitive?: No
Activities
Supervisory Activities
Student/Postdoctoral Supervision
Co-Supervisor
Sima Aurelia - Doctorate - Université de Montréal - In Progress
Student Degree Start Date: 2009/1
Student Degree Expected Date: 2013/6
Project Description: L¿acide rétinoïque dans l¿obésité et le diabète de type 2
Present Position: Ph.D. Student
Principal
Supervisor
Lorena Iglesias - Master's Thesis - Université de Montréal - Completed
Student Degree Start Date: 2009/1
Student Degree Received Date: 2011/6
Project Description: Évaluation d'un prototype d'un détecteur de glucose
photonique.
Present Position: public sector
Co-Supervisor
Constantin Manolescu Daniel - Doctorate - Université de Montréal - In Progress
Student Degree Start Date: 2009/1
Student Degree Expected Date: 2013/6
Project Description: Retinoic acid and insulin resistance in the development of
type 2 diabetes
Present Position: Ph.D. Student
Co-Supervisor
Janie Houle, - Post-doctorate - UQAM - Completed
Student Degree Start Date: 2007/1
Student Degree Received Date: 2011/12
Project Description: Impact de la dépression sur les comportements d'autogestion du diabète
Present Position: academic sector
Principal
Supervisor
Zebdi Samia - Bachelor's - UQTR - Completed
Student Degree Start Date: 2007/1
Student Degree Received Date: 2007/4
Project Description: Le rôle de l'hyperglycémie post-prandiale dans les
complications coronariennes
Principal
Supervisor
Brindisi Marie-Claude - Post-doctorate - CHU Bocage (Dijon, France) Completed
Student Degree Start Date: 2004/12
Student Degree Received Date: 2007/4
Project Description: Effets de l'acarbose et du répaglinide sur le stress
oxydatif...
Present Position: Endocrinologist, Dijon (France)
7
DRAFT
Dr. Jean-Louis Chiasson
Principal
Supervisor
Geneviève Beauregard, - Master's Thesis - Université de Montréal - Completed
Student Degree Start Date: 2003/1
Student Degree Received Date: 2005/1
Project Description: Étude de la régulation de l'expression des gènes par
l'insuline et le glucose
Principal
Supervisor
Demiana Ekladous, - Master's Thesis - Université de Montréal - Completed
Student Degree Start Date: 2003/1
Student Degree Received Date: 2005/6
Project Description: Hepatic resistance to glucagon
Co-Supervisor
Amélie Pelletier, - Doctorate - Université de Montréal - Completed
Student Degree Start Date: 2000/6
Student Degree Received Date: 2006/6
Project Description: Regulation of glucose uptake in cardiomyocytes
Present Position: Research Coordinator
Principal
Supervisor
Sandra Bérubé, - Master's Thesis - Université de Montréal - Completed
Student Degree Start Date: 2000/6
Student Degree Received Date: 2003/7
Project Description: Insulin sensitivity in a healthy population
Present Position: private sector
Principal
Supervisor
Yamina Boukhors, - Master's Thesis - Université de Montréal - Completed
Student Degree Start Date: 1998/9
Student Degree Received Date: 2003/8
Project Description: Use of information technology for management of ITT in
type 1 diabetes
Present Position: other
International Collaboration Activities
2008-01-01 Member
United Kingdom
Activity Description: The Acarbose Cardiovascular Evaluation (ACE) Trial
Contributions
Presentations
2013-09-28
"Prevention of diabetes: Are we there yet?", At the Heart of Diabetes. An
Essential Primer for Cardiovascular Renal and Metabolic Risk Reduction in
Diabetes., Canada, Ontario, Toronto
Main Audience: Researcher
Invited?: Yes
2013-09-25
Vincent Poitout, "La glucotoxicité et la lipotoxicité dans le développement du
diabète de type 2 et des complications vasculaires : approches fondamentales
et cliniques.", Séminaire de la direction scientifique, Département de médecine,
CHUM, Canada, Quebec, Montreal
Main Audience: Researcher
Invited?: Yes
8
DRAFT
Dr. Jean-Louis Chiasson
2013-04-19
"Lignes directrices de pratique clinique pour la prévention et le traitement du
diabète 2013", Endocrine Grand Round, Division of Endocrinology, CHUM,
Canada, Quebec, Montreal
Main Audience: Researcher
Invited?: Yes
2013-03-29
"Pré-diabète: fault-il le traiter ?", Congrès de la Société Francophone du diaète
2013, France, Montpellier
Main Audience: Researcher
Invited?: Yes
2013-02-05
"Treatment of diaetes mellitus and the vascular complications.", SANOFI Guest
speaker, Canada, Quebec, Laval
Main Audience: Researcher
Invited?: Yes
2012-11-29
"Treating postprandial hyperglycaemia for the prevention of cardiovascular
disease.", National Atherosclerosis and Cardiometabolic Forum, Canada,
Ontario, Toronto
Main Audience: Researcher
Invited?: Yes
2012-11-13
"Les complications vasculaires du diabète de type 2: peut-on les freiner?", Eli
Lilly Guest Speaker, Canada, Quebec, Montreal
Main Audience: Researcher
Invited?: Yes
2012-10-26
"Mieux traiter les troubles métaboliques des patients VIH en 2012.", Dépistage
et gestion du diabète chez le patient VIH, Canada, Quebec, Montréal
Main Audience: Researcher
Invited?: Yes
2012-07-13
"Treating postprandial plasma glucose for the prevention of diabetes and CVD:
the STOP-NIDDM Trial.", Bayer Scientific Meeting., China, Beijing
Main Audience: Researcher
Funding Sources: Bayer HealthCare AG - 0
2012-04-14
"La glycémie postprandiale et le risque cardiovasculaire.", Bayer Scientific
Symposium, Tunisia, Djerba
Main Audience: Researcher
Funding Sources: Bayer AG - 0
2012-04-13
"Le rôle des incrétines dans le diabète de type 2.", 21e Congrès National
d'Endocrinologie de la Société Tunisienne d'Endocrinologie, Diabète et
Maladies Métaboliques, Tunisia, Tunis
Main Audience: Researcher
Funding Sources: Bayer AG - 0
2012-04-13
"Le traitement de l'hyperglycémie postprandiale pour la prévention du diabète et
des complications cardiovasculaires.", 21e Congrès National d'Endocrinologie
de la Société Tunisienne d'Endocrinologie, Diabète et Maladies Métaboliques,
Tunisia, Tunis
Main Audience: Researcher
Funding Sources: Bayer AG - 0
9
DRAFT
Dr. Jean-Louis Chiasson
2012-04-12
"La glycémie et le risque cardiovasculaire.", Bayer Guest Speaker, Tunisia,
Tunis
Main Audience: Researcher
Funding Sources: Bayer AG - 0
2012-04-11
"La glycémie postprandiale et le risque cardiovasculaire.", Bayer Guest
Speaker, Tunisia, Sfax
Main Audience: Researcher
Funding Sources: Bayer AG - 0
2011-12-05
"Disposition index and the conversion of IGT to diabetes mellitus: The STOPNIDDM Trial.", International Diabetes Federation 2011 (IDF 2011). Session:
Insulin resistance in young and old., United Arab Emirates, Dubai
Main Audience: Researcher
2011-08-26
"Le rôle de la microflore intestinale dans le développement de l'obésité.", Guest
Speaker Sanofi, Scientific Grand Round, Division of Endocrinology, CHUM,
Canada, Quebec, Montréal
Main Audience: Researcher
2011-07-19
"Glucose control and cardiovascular disease.", ACE Regional Investigator
Meeting, Speaker Tour, China, Guangzhou
Main Audience: Researcher
2011-07-17
"Glucose control and cardiovascular disease.", ACE Regional Investigator
Meeting, Speaker Tour., China, Hangzhou
Main Audience: Researcher
2011-06-02
"Traiter l'hyperglycémie postprandiale pour la prévention du diabète et
des complications vasculaires.", Sanofi Aventis Guest speaker, Division of
Endocrinology, Montreal Jewish Hospital., Canada, Quebec, Montreal
Main Audience: Researcher
2011-05-05
"Traiter l'hyperglycémie postprandiale pour diminuer le risque de diabète et de
ses complications vasculaires.", Bayer Workshop., France, Nice
Main Audience: Researcher
2011-03-05
"How to achieve safe and long-term glycaemic control with cardiovascular
benefits.", Bayer Schering Pharma, 2nd Cardiovascular Risk Management
Symposium. The Challenge of Cardiovascular Disease Prevention., France,
Nice
Main Audience: Researcher
2010-05-30
"CSN Debate: Hemoglobin A1C should be normalized with intensive insulin
therapy to prevent macro- and microvascular disease in type 2 diabetes.
Affirmative: Jean-Louis Chiasson, Negative: Richard Gilbert", Canadian Society
of Nephrology Annual General Meeting 2010., Canada, Quebec, Montreal
Main Audience: Researcher
2010-05-15
"L'hyperglycémie post-prandiale, son rôle délétère et sa prise en charge.",
Congrès annuel de la Société Algérienne de Diabétologie., Algeria, Alger
Main Audience: Researcher
2010-05-15
"La prévention du diabète de type 2.", Congrès annuel de la Société Algérienne
de Diabétologie., Algeria, Alger
Main Audience: Researcher
10
DRAFT
Dr. Jean-Louis Chiasson
2010-05-08
"Evidence for CV benefits with acarbose intervention.", Bayer Schering Pharma
Asia-Pacific Cardiovascular Risk Management Expert Workshop., Taiwan,
Province of China, Taipei
Main Audience: Researcher
2010-05-07
"Effects of oral diabetic drugs on CVD.", Bayer Schering Pharma Asia-Pacific
ACE Speaker. Training Workshop., Taiwan, Province of China, Taipei
Main Audience: Researcher
2010-04-22
"Atteindre les cibles en diabète: Nouvelles options pour l'insulinothérapie.",
Sanofi Aventis Guest Speaker. Division of Endocrinology, Montreal Jewish
Hospital., Canada, Quebec, Montreal
Main Audience: Researcher
2009-10-20
"Guest speaker and Chairman: Intervention multifactorielle dans le traitement
du diabète de type 2.", Optimizing long-term glycemic control in type 2 diabetes:
Overcoming a progressive pathophysiology with incretin therapie (WorldWIDE),
Symposium during the 20th IDF World Diabetes Congress., Canada, Quebec,
Montreal
Main Audience: Researcher
2009-10-20
"Debate on Primary prevention programmes for diabetes: lifestyle versus drugs
- Drugs.", 20th IDF World Diabetes Congress., Canada, Quebec, Montreal
Main Audience: Researcher
2009-10-18
"Guest speaker and Chairman. Glucose lowering interventions in diabetes and
CVD - lessons from outcome studies.", Bayer Healthcare Satellite Symposium,
20th IDF World Diabetes Congress, Canada, Quebec, Montreal
Main Audience: Researcher
2009-10-18
"Traiter l'hyperglycémie postprandiale pour diminuer le risque de diabète et de
ses complications vasculaires.", Bayer Healthcare Meet the Expert Session,
20th IDF World Diabetes Congress., Canada, Quebec, Montreal
Main Audience: Researcher
2009-10-08
"Postprandial peak reduction and its implication in the prevention of CV risk
and diabetes.", Congress of Obesity, Metabolic Syndrome and Prediabetes.,
Venezuela, Bolivarian Republic of, Caracas
Main Audience: Researcher
2009-05-29
"La prévention du diabète de type 2 et de ses complications.", Guest speaker
Eli Lilly, Division of Endocrinology., Canada, New Brunswick, Moncton
Main Audience: Researcher
2009-04-24
"Stratégies de sensibilisation à l'insuline et d'apport d'insuline dans le traitement
du diabète de type 2. Quand et pourquoi ?", Diabetes Forum., Canada, Quebec,
Montreal
Main Audience: Researcher
2009-02-28
"Postprandial plasma glucose as a risk factor for cardiovascular disease.",
Endocrine Grand Round, Division of Endocrinology, University of Toronto.,
Canada, Ontario, Toronto
Main Audience: Researcher
2009-02-27
"The benefits of early insulin as opposed to oral hypoglycemic agents in type
2 diabetes.", Canadian Society of Endocrinology and Metabolism., Canada,
Ontario, Toronto
Main Audience: Researcher
11
DRAFT
Dr. Jean-Louis Chiasson
2009-02-26
"L'insulinothérapie : Initiation pratique et nouvelles insulines.", SSVQ
Symposium (Société des sciences vasculaires du Québec) - Le diabète:
démystifier l'insulinothérapie et les nouveaux hypoglycémiants oraux., Canada,
Quebec, Montreal
Main Audience: Researcher
Interviews and Media Relations
Broadcast Interviews
2013-01-15 2013-01-15
Type 2 diabetes
"Les docteurs" - Radio-Canada
Publications
PubMed Articles
Chiasson JL, "Acarbose for the prevention of diabetes, hypertension, and
cardiovascular disease in subjects with impaired glucose tolerance: the Study
to Prevent Non-Insulin-Dependent Diabetes Mellitus (STOP-NIDDM) Trial.",
Endocrine practice : official journal of the American College of Endocrinology
and the American Association of Clinical Endocrinologists, 12 Suppl 1
PubMed ID: 16627376
2013-06-04
Althouse AD , Abbott JD , Sutton-Tyrrell K , Forker AD , Lombardero MS ,
Buitrón LV , Pena-Sing I , Tardif JC , Mori Brooks M ,, "Favorable Effects of
Insulin Sensitizers Pertinent to Peripheral Arterial Disease in Type 2 Diabetes:
Results from the Bypass Angioplasty Revascularization Investigation 2 Diabetes
(BARI 2D) trial.", Diabetes care
PubMed ID: 23735723
2013-05-08
Leong A , Dasgupta K , Chiasson JL , Rahme E, "Estimating the Population
Prevalence of Diagnosed and Undiagnosed Diabetes.", Diabetes care
PubMed ID: 23656982
2013-04-30
Tamis-Holland JE , Lu J , Korytkowski M , Magee M , Rogers WJ , Lopes
N , Mighton L , Jacobs AK ,, "Sex differences in presentation and outcome
among patients with type 2 diabetes and coronary artery disease treated with
contemporary medical therapy with or without prompt revascularization: a report
from the BARI 2D Trial (Bypass Angioplasty Revasc", Journal of the American
College of Cardiology, 61(17)
PubMed ID: 23500245
2013-04-16
Farkouh ME , Boden WE , Bittner V , Muratov V , Hartigan P , Ogdie M ,
Bertolet M , Mathewkutty S , Teo K , Maron DJ , Sethi SS , Domanski M ,
Frye RL , Fuster V, "Risk factor control for coronary artery disease secondary
prevention in large randomized trials.", Journal of the American College of
Cardiology, 61(15)
PubMed ID: 23500281
2013-03-07
Ismail-Beigi F , Lombardero MS , Escobedo J , Genuth S , Green J , Massaro
E , Mooradian AD , Ovalle F , Whitehouse F , Zonszein J ,, "Determinants of
successful glycemic control among participants in the BARI 2D Trial: A Post-hoc
Analysis.", Journal of diabetes and its complications
PubMed ID: 23478173
12
DRAFT
Dr. Jean-Louis Chiasson
2013-01-01
Wolever, T.M.S., Gibbs, A.L., Chiasson, J.L., Connelly, P.W., Josse, R.G.,
Leiter, L.A., Maheux, P., Rabasa-Lhoret, R., Rodger, N.W., Ryan, E.A., "Altering
source or amount of dietary carbohydrate has acute and chronic effects on
postprandial glucose and triglycerides in type 2 diabetes: Canadian trial of
Carbohydrates in Diabetes (CCD).", Nutr. Metab. Cardiovasc. Dis., 23
PubMed ID: 22397878
2012-12-20
Farkouh ME , Domanski M , Sleeper LA , Siami FS , Dangas G , Mack M , Yang
M , Cohen DJ , Rosenberg Y , Solomon SD , Desai AS , Gersh BJ , Magnuson
EA , Lansky A , Boineau R , Weinberger J , Ramanathan K , Sousa JE , Rankin
J , Bhargava B , Buse J , Hueb W , Smith CR , Muratov V , Bansilal S , King S ,
Bertrand M , Fuster V ,, "Strategies for multivessel revascularization in patients
with diabetes.", The New England journal of medicine, 367(25)
PubMed ID: 23121323
2012-12-01
Bergenstal RM , Forti A , Chiasson JL , Woloschak M , Boldrin M , Balena R,
"Efficacy and safety of taspoglutide versus sitagliptin for type 2 diabetes mellitus
(T-emerge 4 trial).", Diabetes therapy : research, treatment and education of
diabetes and related disorders, 3(1)
PubMed ID: 23138449
2012-07-01
Hanefeld M , Pistrosch F , Koehler C , Chiasson JL, "Conversion of IGT to type
2 diabetes mellitus is associated with incident cases of hypertension: a post-hoc
analysis of the STOP-NIDDM trial.", Journal of hypertension, 30(7)
PubMed ID: 22573126
2012-03-23
Henderson M , Baillargeon JP , Rabasa-Lhoret R , Chiasson JL , Hanley J ,
Lambert M, "Estimating insulin secretion in youth using simple indices derived
from the oral glucose tolerance test.", Diabetes & metabolism
PubMed ID: 22445514
2012-03-05
Wolever TM , Gibbs AL , Chiasson JL , Connelly PW , Josse RG , Leiter LA ,
Maheux P , Rabasa-Lhoret R , Rodger NW , Ryan EA, "Altering source or
amount of dietary carbohydrate has acute and chronic effects on postprandial
glucose and triglycerides in type 2 diabetes: Canadian trial of Carbohydrates in
Diabetes (CCD).", Nutrition, metabolism, and cardiovascular diseases : NMCD
PubMed ID: 22397878
2011-12-01
Broderick TL , El Midaoui A , Chiasson JL , Wang D , Jankowski M , Gutkowska
J, "The effects of exercise training on #-butyrobetaine hydroxylase and novel
organic cation transporter-2 gene expression in the rat.", Applied physiology,
nutrition, and metabolism = Physiologie appliquée, nutrition et métabolisme,
36(6)
PubMed ID: 22014179
2011-06-01
"Incidence of diabetes following ramipril or rosiglitazone withdrawal.", Diabetes
care, 34(6)
PubMed ID: 21515846
2011-03-01
Gerstein HC , Mohan V , Avezum A , Bergenstal RM , Chiasson JL , Garrido M ,
MacKinnon I , Rao PV , Zinman B , Jung H , Joldersma L , Bosch J , Yusuf S,
"Long-term effect of rosiglitazone and/or ramipril on the incidence of diabetes.",
Diabetologia, 54(3)
PubMed ID: 21116607
13
DRAFT
Dr. Jean-Louis Chiasson
2011-02-01
Singh PP , Abbott JD , Lombardero MS , Sutton-Tyrrell K , Woodhead G ,
Venkitachalam L , Tsapatsaris NP , Piemonte TC , Lago RM , Rutter MK , Nesto
RW ,, "The prevalence and predictors of an abnormal ankle-brachial index in the
Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) trial.",
Diabetes care, 34(2)
PubMed ID: 21270200
2011-02-01
Henderson M , Rabasa-Lhoret R , Bastard JP , Chiasson JL , Baillargeon
JP , Hanley JA , Lambert M, "Measuring insulin sensitivity in youth: How do
the different indices compare with the gold-standard method?", Diabetes &
Metabolism, 37(1)
PubMed ID: 21126900
2010-02-01
Tuomilehto J , Lindström J , Hellmich M , Lehmacher W , Westermeier T ,
Evers T , Brückner A , Peltonen M , Qiao Q , Chiasson JL, "Development and
validation of a risk-score model for subjects with impaired glucose tolerance for
the assessment of the risk of type 2 diabetes mellitus-The STOP-NIDDM riskscore.", Diabetes research and clinical practice, 87(2)
PubMed ID: 20022651
2009-11-01
Chiasson JL, "Early insulin use in type 2 diabetes: what are the cons?",
Diabetes care, 32 Suppl 2
PubMed ID: 19875563
2009-11-01
de Galan BE , Zoungas S , Chalmers J , Anderson C , Dufouil C , Pillai A ,
Cooper M , Grobbee DE , Hackett M , Hamet P , Heller SR , Lisheng L ,
Macmahon S , Mancia G , Neal B , Pan CY , Patel A , Poulter N , Travert
F , Woodward M ,, "Cognitive function and risks of cardiovascular disease
and hypoglycaemia in patients with type 2 diabetes: the Action in Diabetes
and Vascular Disease: Preterax and Diamicron Modified Release Controlled
Evaluation (ADVANCE) trial.", Diabetologia, 52(11)
PubMed ID: 19688336
2009-11-01
Zoungas S , de Galan BE , Ninomiya T , Grobbee D , Hamet P , Heller S ,
MacMahon S , Marre M , Neal B , Patel A , Woodward M , Chalmers J , ,
Cass A , Glasziou P , Harrap S , Lisheng L , Mancia G , Pillai A , Poulter N ,
Perkovic V , Travert F, "Combined effects of routine blood pressure lowering
and intensive glucose control on macrovascular and microvascular outcomes in
patients with type 2 diabetes: New results from the ADVANCE trial.", Diabetes
care, 32(11)
PubMed ID: 19651921
2009-06-11
Frye RL , August P , Brooks MM , Hardison RM , Kelsey SF , MacGregor JM ,
Orchard TJ , Chaitman BR , Genuth SM , Goldberg SH , Hlatky MA , Jones TL ,
Molitch ME , Nesto RW , Sako EY , Sobel BE, "A randomized trial of therapies
for type 2 diabetes and coronary artery disease.", The New England journal of
medicine, 360(24)
PubMed ID: 19502645
2009-03-01
Hammana I , Coderre L , Potvin S , Costa M , Berthiaume Y , Lavoie A ,
Chiasson JL , Levy E , Rabasa-Lhoret R, "Dichotomy between postprandial
glucose and lipid profiles in adults with cystic fibrosis: a pilot study.", Journal of
cystic fibrosis : official journal of the European Cystic Fibrosis Society, 8(2)
PubMed ID: 19083274
14
DRAFT
Dr. Jean-Louis Chiasson
2009-03-01
Pop-Busui R , Lu J , Lopes N , Jones TL ,, "Prevalence of diabetic peripheral
neuropathy and relation to glycemic control therapies at baseline in the BARI 2D
cohort.", Journal of the peripheral nervous system : JPNS, 14(1)
PubMed ID: 19335534
2009-01-01
Hanefeld M , Karasik A , Koehler C , Westermeier T , Chiasson JL, "Metabolic
syndrome and its single traits as risk factors for diabetes in people with impaired
glucose tolerance: the STOP-NIDDM trial.", Diabetes & vascular disease
research : official journal of the International Society of Diabetes and Vascular
Disease, 6(1)
PubMed ID: 19156626
2008-12-01
Sreenan S , Virkamäki A , Zhang K , Hansen JB ,, "Switching from NPH
insulin to once-daily insulin detemir in basal-bolus-treated patients with
diabetes mellitus: data from the European cohort of the PREDICTIVE study.",
International journal of clinical practice, 62(12)
PubMed ID: 19166444
2008-12-01
Godbout A , Hammana I , Potvin S , Mainville D , Rakel A , Berthiaume Y ,
Chiasson JL , Coderre L , Rabasa-Lhoret R, "No relationship between mean
plasma glucose and glycated haemoglobin in patients with cystic fibrosis-related
diabetes.", Diabetes & metabolism, 34(6 Pt 1)
PubMed ID: 18922724
2008-09-01
Wolever TM , Mehling C , Chiasson JL , Josse RG , Leiter LA , Maheux P ,
Rabasa-Lhoret R , Rodger NW , Ryan EA, "Low glycaemic index diet and
disposition index in type 2 diabetes (the Canadian trial of carbohydrates in
diabetes): a randomised controlled trial.", Diabetologia, 51(9)
PubMed ID: 18648764
2008-09-01
"Baseline characteristics of patients with diabetes and coronary artery disease
enrolled in the Bypass Angioplasty Revascularization Investigation 2 Diabetes
(BARI 2D) trial.", American heart journal, 156(3)
PubMed ID: 18760137
2008-08-01
Ekladous D , Mehdi MZ , Costa M , Srivastava AK , Chiasson JL , Coderre
L, "Tissue- and fibre-specific modifications of insulin-signalling molecules
in cardiac and skeletal muscle of diabetic rats.", Clinical and experimental
pharmacology & physiology, 35(8)
PubMed ID: 18430054
2008-07-01
Cloutier G , Zimmer A , Yu FT , Chiasson JL, "Increased shear rate resistance
and fastest kinetics of erythrocyte aggregation in diabetes measured with
ultrasound.", Diabetes care, 31(7)
PubMed ID: 18375419
2008-06-12
Patel A , MacMahon S , Chalmers J , Neal B , Billot L , Woodward M , Marre
M , Cooper M , Glasziou P , Grobbee D , Hamet P , Harrap S , Heller S , Liu
L , Mancia G , Mogensen CE , Pan C , Poulter N , Rodgers A , Williams B ,
Bompoint S , de Galan BE , Joshi R , Travert F, "Intensive blood glucose control
and vascular outcomes in patients with type 2 diabetes.", The New England
journal of medicine, 358(24)
PubMed ID: 18539916
15
DRAFT
Dr. Jean-Louis Chiasson
2008-05-01
Dagenais GR , Gerstein HC , Holman R , Budaj A , Escalante A , Hedner T ,
Keltai M , Lonn E , McFarlane S , McQueen M , Teo K , Sheridan P , Bosch
J , Pogue J , Yusuf S, "Effects of ramipril and rosiglitazone on cardiovascular
and renal outcomes in people with impaired glucose tolerance or impaired
fasting glucose: results of the Diabetes REduction Assessment with ramipril and
rosiglitazone Medication (DREAM) trial.", Diabetes care, 31(5)
PubMed ID: 18268075
2008-01-01
Wolever TM , Gibbs AL , Mehling C , Chiasson JL , Connelly PW , Josse
RG , Leiter LA , Maheux P , Rabasa-Lhoret R , Rodger NW , Ryan EA, "The
Canadian Trial of Carbohydrates in Diabetes (CCD), a 1-y controlled trial of lowglycemic-index dietary carbohydrate in type 2 diabetes: no effect on glycated
hemoglobin but reduction in C-reactive protein.", The American journal of
clinical nutrition, 87(1)
PubMed ID: 18175744
2007-12-01
Chiasson JL, "Prevention of Type 2 diabetes: fact or fiction?", Expert opinion on
pharmacotherapy, 8(18)
PubMed ID: 18035959
2007-11-30
Costa M , Potvin S , Hammana I , Malet A , Berthiaume Y , Jeanneret A , Lavoie
A , Lévesque R , Perrier J , Poisson D , Karelis AD , Chiasson JL , RabasaLhoret R, "Increased glucose excursion in cystic fibrosis and its association
with a worse clinical status.", Journal of cystic fibrosis : official journal of the
European Cystic Fibrosis Society, 6(6)
PubMed ID: 17409029
2007-10-01
Godbout A , Chiasson JL, "Who should benefit from the use of alphaglucosidase inhibitors?", Current diabetes reports, 7(5)
PubMed ID: 18173965
2007-09-08
Patel A , , MacMahon S , Chalmers J , Neal B , Woodward M , Billot L , Harrap
S , Poulter N , Marre M , Cooper M , Glasziou P , Grobbee DE , Hamet P ,
Heller S , Liu LS , Mancia G , Mogensen CE , Pan CY , Rodgers A , Williams B,
"Effects of a fixed combination of perindopril and indapamide on macrovascular
and microvascular outcomes in patients with type 2 diabetes mellitus (the
ADVANCE trial): a randomised controlled trial.", Lancet, 370(9590)
PubMed ID: 17765963
2007-09-01
Fontaine-Bisson B , Wolever TM , Chiasson JL , Rabasa-Lhoret R , Maheux
P , Josse RG , Leiter LA , Rodger NW , Ryan EA , Connelly PW , Corey PN ,
El-Sohemy A, "Genetic polymorphisms of tumor necrosis factor-alpha modify
the association between dietary polyunsaturated fatty acids and fasting HDLcholesterol and apo A-I concentrations.", The American journal of clinical
nutrition, 86(3)
PubMed ID: 17823444
2007-06-01
Hammana I , Malet A , Costa M , Brochiero E , Berthiaume Y , Potvin S ,
Chiasson JL , Coderre L , Rabasa-Lhoret R, "Normal adiponectin levels despite
abnormal glucose tolerance (or diabetes) and inflammation in adult patients with
cystic fibrosis.", Diabetes & metabolism, 33(3)
PubMed ID: 17418606
16
DRAFT
Dr. Jean-Louis Chiasson
2007-06-01
Chui MH , Papanikolaou Y , Fontaine-Bisson B , Turcotte J , Wolever TM , ElSohemy A , Chiasson JL , Rabasa-Lhoret R , Maheux P , Ryan E , Greenwood
CE, "The TNF-alpha-238G > a single-nucleotide polymorphism protects against
memory decline in older adults with type 2 diabetes.", Behavioral neuroscience,
121(3)
PubMed ID: 17592954
2007-05-01
Fontaine-Bisson B , Wolever TM , Chiasson JL , Rabasa-Lhoret R , Maheux P ,
Josse RG , Leiter LA , Rodger NW , Ryan EA , El-Sohemy A, "Tumor necrosis
factor alpha -238G>A genotype alters postprandial plasma levels of free fatty
acids in obese individuals with type 2 diabetes mellitus.", Metabolism: clinical
and experimental, 56(5)
PubMed ID: 17445540
2007-04-01
Andrulionyte L , Kuulasmaa T , Chiasson JL , Laakso M ,, "Single nucleotide
polymorphisms of the peroxisome proliferator-activated receptor-alpha gene
(PPARA) influence the conversion from impaired glucose tolerance to type 2
diabetes: the STOP-NIDDM trial.", Diabetes, 56(4)
PubMed ID: 17317762
2007-04-01
Meugnier E , Faraj M , Rome S , Beauregard G , Michaut A , Pelloux V ,
Chiasson JL , Laville M , Clement K , Vidal H , Rabasa-Lhoret R, "Acute
hyperglycemia induces a global downregulation of gene expression in adipose
tissue and skeletal muscle of healthy subjects.", Diabetes, 56(4)
PubMed ID: 17303805
2007-02-01
Pelletier A , Tardif A , Gingras MH , Chiasson JL , Coderre L, "Chronic exposure
to ketone bodies impairs glucose uptake in adult cardiomyocytes in response to
insulin but not vanadate: the role of PI3-K.", Molecular and cellular biochemistry,
296(1-2)
PubMed ID: 16960657
2007-01-01
Brindisi MC , Hahn J , Chiasson JL , Rabasa-Lhoret R, "Under-utilization of
capillary glucose monitoring by type 2 diabetic patients.", Diabetes research and
clinical practice, 75(1)
PubMed ID: 16814897
2006-10-12
Bosch J , Yusuf S , Gerstein HC , Pogue J , Sheridan P , Dagenais G , Diaz R ,
Avezum A , Lanas F , Probstfield J , Fodor G , Holman RR, "Effect of ramipril on
the incidence of diabetes.", The New England journal of medicine, 355(15)
PubMed ID: 16980380
2006-09-23
Gerstein HC , Yusuf S , Bosch J , Pogue J , Sheridan P , Dinccag N , Hanefeld
M , Hoogwerf B , Laakso M , Mohan V , Shaw J , Zinman B , Holman RR,
"Effect of rosiglitazone on the frequency of diabetes in patients with impaired
glucose tolerance or impaired fasting glucose: a randomised controlled trial.",
Lancet, 368(9541)
PubMed ID: 16997664
2006-08-01
Andrulionyte L , Laukkanen O , Chiasson JL , Laakso M ,, "Single nucleotide
polymorphisms of the HNF4alpha gene are associated with the conversion to
type 2 diabetes mellitus: the STOP-NIDDM trial.", Journal of molecular medicine
(Berlin, Germany), 84(8)
PubMed ID: 16838170
17
DRAFT
Dr. Jean-Louis Chiasson
2006-07-01
Andrulionyte L , Peltola P , Chiasson JL , Laakso M ,, "Single nucleotide
polymorphisms of PPARD in combination with the Gly482Ser substitution of
PGC-1A and the Pro12Ala substitution of PPARG2 predict the conversion
from impaired glucose tolerance to type 2 diabetes: the STOP-NIDDM trial.",
Diabetes, 55(7)
PubMed ID: 16804087
2006-06-19
Sobel BE ,, "Ancillary studies in the Bypass Angioplasty Revascularization
Investigation 2 Diabetes (BARI 2D) Trial: Synergies and opportunities.", The
American journal of cardiology, 97(12A)
PubMed ID: 16813738
2006-06-19
Albu J , Gottlieb SH , August P , Nesto RW , Orchard TJ ,, "Modifications of
coronary risk factors.", The American journal of cardiology, 97(12A)
PubMed ID: 16813737
2006-06-19
Barsness GW , Gersh BJ , Brooks MM , Frye RL ,, "Rationale for the
revascularization arm of the Bypass Angioplasty Revascularization Investigation
2 Diabetes (BARI 2D) Trial.", The American journal of cardiology, 97(12A)
PubMed ID: 16813736
2006-06-19
Steiner G ,, "Statement of the problem.", The American journal of cardiology,
97(12A)
PubMed ID: 16813733
2006-06-19
Magee MF , Isley WL ,, "Rationale, design, and methods for glycemic control in
the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D)
Trial.", The American journal of cardiology, 97(12A)
PubMed ID: 16813735
2006-06-19
Brooks MM , Frye RL , Genuth S , Detre KM , Nesto R , Sobel BE , Kelsey SF ,
Orchard TJ ,, "Hypotheses, design, and methods for the Bypass Angioplasty
Revascularization Investigation 2 Diabetes (BARI 2D) Trial.", The American
journal of cardiology, 97(12A)
PubMed ID: 16813734
2006-06-19
Hlatky MA , Melsop KA , Boothroyd DB ,, "Economic evaluation of alternative
strategies to treat patients with diabetes mellitus and coronary artery disease.",
The American journal of cardiology, 97(12A)
PubMed ID: 16813739
2006-04-13
Lonn E , Yusuf S , Arnold MJ , Sheridan P , Pogue J , Micks M , McQueen
MJ , Probstfield J , Fodor G , Held C , Genest J ,, "Homocysteine lowering with
folic acid and B vitamins in vascular disease.", The New England journal of
medicine, 354(15)
PubMed ID: 16531613
2006-04-01
Brindisi MC , Rabasa-Lhoret R , Chiasson JL, "Postprandial hyperglycaemia: to
treat or not to treat?", Diabetes & metabolism, 32(2)
PubMed ID: 16735958
2006-02-01
El Midaoui A , Chiasson JL , Tancrède G , Nadeau A, "Physical training
reverses the increased activity of the hepatic ketone body synthesis pathway in
chronically diabetic rats.", American journal of physiology. Endocrinology and
metabolism, 290(2)
PubMed ID: 16403781
18
DRAFT
Dr. Jean-Louis Chiasson
2006-01-01
Lonn E , Held C , Arnold JM , Probstfield J , McQueen M , Micks M , Pogue J ,
Sheridan P , Bosch J , Genest J , Yusuf S ,, "Rationale, design and baseline
characteristics of a large, simple, randomized trial of combined folic acid and
vitamins B6 and B12 in high-risk patients: the Heart Outcomes Prevention
Evaluation (HOPE)-2 trial.", The Canadian journal of cardiology, 22(1)
PubMed ID: 16450017
Journal Articles
2011/1
Chiasson, J.L. and Bernard, S., "Reducing cardiovascular risk factors in patients
Published
with pre-diabetes.", Diabetes Management, 1, 423-438
First Listed Author
2008/
Published
Co-Author
Ur, E., Chiasson, J.L., Ransom, T., Rowe, R., "Screening for type 1 and type 2
diabetes.", Can. J. Diabetes, 32(Suppl 1), S14-S16
2008/
Published
Co-Author
Ur, E., Chiasson, J.L., Ransom, T., Rowe, R., "Prevention of diabetes.", Can. J.
Diabetes, 32(Suppl 1), S17-S19
2006/
Chiasson, J.L., "Pharmacological and surgical intervention for the prevention of
Published
diabetes.", Nestlé Nutrition Workshop Ser. Clin. Perform. Programme, 11, 31-42
First Listed Author
Book Chapters
2012/
"Decreasing postprandial plasma glucose in subjects with IGT using an #
In Press
(alpha)-glucosidase inhibitor for the prevention of type 2 diabetes mellitus:
First Listed Author The STOP-NIDDM Trial.", Prevention of type 2 diabetes; From Science to
Therapies, LeRoith, D., Ed., Springer Science
Authors: Chiasson, J.L., Laakso, M., and Hanefeld, M.:
2012/
In Press
Last Author
"Prevention of type 2 diabetes (chapter 38).", Diabetes in America, NIH
Authors: Knowler, B., Chiasson, J.L.
Clinical Care Guidelines
2012-04-03
"2013 Clinical Practice Guidelines for the Prevention and Management of
Diabetes in Canada"
Description / Contribution Value: The purpose of this review was to determine
that there was no salient information missing, no conflicting recommendations,
and that the recommendations are generally applicable to clinical practice.
19