docMedicinal and organic chemistry
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Medicinal and organic chemistry
content | menu en FR Research SEARCH Centre d'études et de recherche sur le médicament de Normandie Ouvrir le menu Fermer le menu Research programmes Polypharmacology Protein-Protein Interactions Platforms Medicinal and organic chemistry Chemoinformatics Chemical library Screening and drugability Organisation and Staff Teachers/Researchers Technical staff Post-docs PhD students Scientific output Publications Conferences Oral communications Master's degree in drug design Alumni How you can support research News Home > Platforms > Medicinal and organic chemistry Medicinal and organic chemistry Chemoinformatics Chemical library PAGE 1 SUR 3 Screening and drugability Medicinal and organic chemistry The activity of the medicinal and organic chemistry platform is based on a permanent staff including five professors, five associate professors (one of whom is accredited to supervise PhDs), four research engineers a n d o n e t e c h n i c i a n . The platform disposes of an analytical infrastructure including a 400Mhz NMR spectrometer, a X-ray diffraction device, a HPLC chain coupled to a mass spectrometer, three automated chromatographic flash systems, an IRTF spectrometer and two microwave reactors, all of which ensure total independence in its analytical capacities. Its main activity is linked to the research programmes developed within two scientific themes: polypharmacology and protein-protein interactions. The platform has developed expertise in the methodology of heterocyclic synthesis using metal-catalysed coupling reactions, new methods for the selective functionalization of heterocycles using either organometallic bases or metal-catalysed C-H activation reactions. These methodologies are particularly suited to the synthesis of original molecules with a therapeutic or diagnostic interest. New synthetic approaches for smooth functionalization of aromatic rings by C-H activation are being developed and are notably used in the synthesis of ligands and radioligands for medical imaging. This chemical expertise is particularly suited to the drug design procedures used in the CERMN's medicinal chemistry programmes: hit-to-lead chemistry, lead optimization... Download page Last update : July 4, 2016 CONTACT Pr Frédéric Fabis +33 (0)2 31 56 68 08 [email protected] portail de la recherche mentions légales informatique et libertés cookies & statistiques Université de Caen Normandie CERMN · Centre d'études et de recherche sur le médicament de Normandie Boulevard Becquerel | 14032 Caen Cedex | France se rendre à l'université PAGE 2 SUR 3 contact UNICAEN PAGE 3 SUR 3
