Should-endometriosis-women-with-infertility-with-age35

Should endometriosis women with infertility with age>35 years do IVF before
laparoscopic surgery?
Abstract ID : 1696
Soumis par : Yan Yu Le 2016-03-15 02:46:06
Nom de la catégorie : SEUD CONGRESS
Typologie : Communication orale / Oral communication
Statut : validé
Autorisation de diffusion : Yes/Oui
------------------------------------Introduction:
Endometriosis is a common, chronic disease, which estimated to affect up to 10% to 15% of reproductive-age women.
Approximately, 25% to 50% of infertile women have endometriosis and 30% to 50% of women with endometriosis are
infertile. Although the treatment of women with endometriosis associated with infertility is well described, it is still a
controversy of how to trat old women with endometriosis associated with infertility, IVF before surgery or laparoscopic
surgery first? The objective of the study was to investgate whether IVF before the surgery inol women with
endometriosis associated with infertility could obtain a better pregnancy outcome.
Materials /Patients and methods:
A retrospective observational study was carried out on 45 infertile patients with range of the age from 35 to 42. All
patients first dignosed endometriosis-associated cyst with the diameters of 5-8cm by ultrasound or Magnetic Resonance
Imaging. All patients had no positive reaults in uterus, ovulation and tubal patency. Among of them, 20 patients
underwent laparoscopic surgery for endometriosis cyst and GnRHa treatment of 3 months at follow-up in vitro
fertilization and embryo transfer (IVF-ET). 25 patients underwent endometriosis cyst by puncture at follow-up IVF-ET.
Results: our preliminary results showed that the numbers of oocyte in the surgery approach was more decreased
significantly than the puncture approach (P<0.05). The fertilization rate of IVF in the surgery approach was more
reduced significantly than the puncture approach (P<0.05). The pregnancy rate in the surgery approach was significantly
lower (4/20, 20%) than the puncture approach(11/25, 44%) (P<0.05). The patients of surgery approach had poorer
ovarian reserve and lower embryo quality than the puncture approach.
Conclusions:
A reasonable evidence demonstrates an association between endometriosis and infertility has not been clearly
established. However, endometriosis can result in adhesions or distorted pelvic anatomy that precludes fertility. This is
debatable that whether the surgery can improve the pregnancy outcome of the infertile women of old age with
endometriosis. Avoiding the operation of the ovary and protecting the ovarian function may be more benifical to the
fertility of women of old age with endometriosis.
------------------------------------Mots clefs : endometriosis women, infertility
Auteurs :
Références : , , ,
Auteurs
Yan Yu 1, Xinmei Zhang 1,
1. CHINA
Auteurs (raw format)
Yan Yu - email : Etablissement : Service : Ville : Pays : CHINA Présentateur : Oui
Xinmei Zhang - email : Etablissement : Service : Ville : Pays : CHINA Présentateur : Non