Untitled - LABEX celtisphybio

8h – 9h : Accueil des participants/welcome of the participants
9h – 9h10 : Ouverture du colloque/oppening of the seminar (Amphi
BDD, Institut Curie)
Session 1, Analyse structurale et fonctionnelles de protéines
membranaires purifiées/Structural and functional analysis of
purified membrane proteins. Chair
9h15 –10h00 : Keynote speaker: H. Poulsen (Aarhus University,
Denmark).
Ion transport by the sodium pump: from the crystal structure to the
identification of hypertension determinants.
10h00-10H15: short talk 1. Pierre-Jean Corringer. (Unité
Récepteurs-Canaux, UMR 3571 du CNRS, Institut Pasteur, Paris).
Transplantation of the transmembrane domain of the human
glycine receptor into its prokaryotic homolog GLIC.
10h15 – 10h30 : short talk 2. Marc Baaden (Institut de Biologie
Physico-Chimique, Paris)
Probing pentameric ligand-gated ion channels with bromoform
reveals many interconnected anesthetic binding sites
10h30- 11h coffee break
11h00 – 11h15 : short talk 3. Guillaume Lenoir (Laboratoire des
Protéines Membranaires
UMR 8221-iBiTec-S/SB2SM, CEA Saclay)
The Drs2p/Cdc50p lipid “flippase” complex: purification and
catalytic properties
11h15-11h30: short talk 4. Halina Wojtowicz (Unité de RMN des
Biomolécules, Institut Pasteur, CNRS UMR 3528, Paris).
Hemophore-mediated transmembrane signaling in Serratia
marcescens: a structural approach ?
11h30 – 11h45 : short talk 5. Aurore Lévy (UMR 168, Institut Curie,
Paris)
Role of caveolin 1 in the sorting of sphingomyelin.
session 2, Analyse structurale et fonctionnelles de protéines
membranaires reconstituées en systèmes modèles/Structural and
functional analysis of reconstituted membrane proteins. Chair
11h45 – 12h30: Olivier Lambert (CBMN-UMR5248, Université de
Bordeaux). Membrane proteins reconstituted in liposome and in
nanodisk/cryo-tomography
12h30-13h30 Buffet (hall BDD)
Session 3 Posters
13h30-15h Posters (Salles annexes BDD 1, 2, 3)
Session 2, Structural and functional analysis of reconstituted
membrane proteins
15h00 – 15h45 : Keynote speaker. Frederic Pincet (ENS, Paris).
Molecular basis of SNARE-induced fusion: energy, membrane
dynamics and regulation.
15H45- 16H : Short talk 6. Beatrice Schaack (IBS, Grenoble)
Toxin action on recombinant human potassium channels recorded
at the single level in an artificial membrane system, a miniaturised
and simple assay
16h – 16h15 : short talk 7. Isabelle Mouro-Chanteloup (INSERM
UMR_S1134 Biologie Intégrée du Globule Rouge, Institut National
de la Transfusion Sanguine, Paris).
Functional studies of membrane proteins AE1 (Band 3) and Rhesus
(Rh) by measurement of kinetics of intracellular pH variations by
stopped-flow analysis on recombiant cells, ghosts or
proteoliposomes.
16h30- 17h15: Keynote speaker M. Nollmann (Centre de Biochimie
Structurale, CNRS UMR 5048 - UM 1 - INSERM UMR 1054,
Montpellier)
Recent advances in super resolution microscopy and their
application to the study of cellular mechanisms.
17h15 – 17h30 : short talk 9. G. Van Niel (Institut Curie, UMR CNRS
144, Paris).
Role of PMEL, a transmembrane protein in the formation of
physiological amyloids fibers in pigment cells.
17h30 – 17h45 : short talk 10. Aurelie Floch (Institut Jacques
Monod, UMR 7592 CNRS, Université Paris Diderot, Paris).
Contribution of karyopherin and lipid binding to nuclear pore
targeting of a yeast nucleoporin.
16h15 – 16h30 : short talk 8. Laura Baciou (Laboratoire de Chimie
Physique, UMR800 CNRS, Université Paris Sud, Orsay).
Conclusions and departure.
Membrane environment directly impacts the capacity of NADPH
oxidase to produce superoxide.
Location
Institut Curie. 11 rue P.M. Curie. Ampitheatre Building Biologie du
Developement. RER B Station Luxembourg.
session 4 Structural and functional analysis of membrane protein
in cells. Chair
Contact: Daniel levy, [email protected]; Phone 33 1 56 24 67 82