Prof. Dr. F. PAULSEN Scientific career, awards and honors 1996

Prof. Dr. F. PAULSEN
Scientific career, awards and honors
1996-1997
Medical employee: Institute of Anatomy of the university of Kiel
1997
MD, University of Kiel
1997-2003
Post Doc, Institute of Anatomy of the University of Kiel
2001
Habilitation (Dr. Sci.) at the University of Kiel with Venia Legendi in Anatomy
2001/02
Visiting Scientist at the Mucin Research Group, Division of Ophthalmology,
National Eye Research Center, University of Bristol, UK (4 month, 3 months)
2001
Specialist in anatomy (Fachanatom) – German Anatomical Society
2002
Dry Eye Research Award of the Dry Eye Group in the professional association
of German ophthalmologists
2002
Teaching Award for outstanding training in anatomy – University of Kiel
2004-2010
Professor for Anatomy at the Martin-Luther-University of Halle-Wittenberg
2006
Gerhard Mann Sicca Research Award
2006-2010
Member of the Faculty Council at Martin Luther University Halle-Wittenberg
2007
Honorary member Anatomical Society of Romania
2007
Corresponding member Anatomical Society of Great Britain and Ireland
since 2010
Head (W3) Department II of Anatomy, University of Erlangen-Nuremberg
Activities
since 1998
Applicant of grants from the DFG (13 conceded grants until today)
2005
Foundation of a Center for Advanced Training in Clinical Anatomy at the Institute of Anatomy and Cell Biology Martin Luther University Halle Wittenberg
2005-2009
Medical & Scientific Advisory Board (MSAB) of the Tear Film and Ocular Surface Society (TFOS)
2006
Dry Eye Workshop Study (DEWS) group member
since 2006
Board of the German Anatomical Society – secretary and treasurer
since 2006
Member of the award committee for Wolfgang-Bargmann award (German
Anatomical Society) and dry eye award (professional association of German
ophthalmologists)
since 2006
Editor-in-Chief of the Annals of Anatomy (Elsevier)
since 2007
Board of the International Society of Eye Research (ISER)
since 2007
Editor of the German Version of Gray’s anatomy for students
since 2009
Councillor of the Tear Film and Ocular Surface Society (TFOS)
2009
Meibomian Gland Workshop group member
since 2009
Board of the Anton-Waldeyer foundation
since 2009
Secretary general of the International Federation of Associations of Anatomy
since 2010
Editor of the 23. Ed. of the “Sobotta” – Atlas of Anatomy
Mentor of the Max Weber program – Elite Network of Bavaria
Editor-in-Chief of the Annals of Anatomy; Member of 5 journals, member of the peer review
board of more than 35 scientific journals. ,
More than 160 publications in peer reviewed journals and proceedings of which more than
140 publications are listed in the Scientific Citation Index (SCI – Web of Science)
Several textbook chapters for different textbooks in Anatomy and Otorhinolaryngology
Ten most important publications in the field
1
Rösler S, Hase T, Claassen H, Schicht M, Schulze U, Riemann D, Brandt J, Wohlrab
D, Müller-Hilke B, Goldring MB, Sel S, Varoga D, Podolsky DK, Paulsen F. TFF3 is
induced during degenerative and inflammatory joint disease, activates MMPs and enhances apoptosis of articular cartilage chondrocytes. Arthritis Rheum 62:815-825,
2010
2
Minsel I, Mentlein R, Sel S, Diebold Y, Bräuer L, Mühlbauer E, Paulsen F. Somatostatin is secreted by the human lacrimal gland into the tear film and acts via somotostatin receptors 1, -2, and –5 which are modulated by inflammatory processes at
the ocular surface. Endocrinology 150:2254-2263, 2009
3
Jäger K, Bönisch U, Risch M, Worlitzsch D, Paulsen F (2009) Detection of cationic
amino acid transporters in the human lacrimal system and their involvement in ocular
surface disease. Invest Ophthalmol Vis Sci 50:1112-1121
4
Paulsen F, Woon CW, Varoga D, Jansen A, Jäger K, Amm M, Podolsky D, Barker N,
Steven P, Sel S. Tff3 promotes corneal wound healing in mice. J Biol Chem
283:13418-13427, 2008
5
Bräuer L, Kindler C, Jäger K, Sel S, Nölle B, Pleyer U, Ochs M, Paulsen F (2007)
Detection of surfactant proteins A and D in human tear fluid and the human lacrimal
system. Invest Ophthalmol Vis Sci 48:3945-3953
6
Varoga D, Pufe T, Harder J, Schröder JM, Mentlein R, Goldring MB, Meyer-Hoffert U,
Tillmann B, Hassenpflug J, Paulsen F. Human beta-defensin-3 mediates tissue remodelling processes in articular cartilage by increasing metalloproteinases and reducing their endogenous inhibitors TIMP-1 and 2. Arthritis Rheum 51:1736-1745, 2005
7
Gebhardt M, Mentlein R, Schaudig U, Pufe T, Nölle B, Al-Samir K, Geerling G,
Paulsen F (2005) Differential expression of VEGF corroborates the limbal origin of
pterygia. Ophthalmology 112:1023-1030
8
Ayub M, Thale A, Hedderich J, Tillmann B, Paulsen F (2003) The cavernous body of
the human efferent tear ducts functions in regulation of tear outflow. Invest Ophthalmol Vis Sci 44:4900-4907
9
Paulsen F, Steven P, Tsokos M, Jungmann K, Müller A, Verse T, Pirsig W Structural
indications of a progressive snorers disease in an upper airway epithelium. Am J Respir Crit Care Med 166:501-509, 2002.
10
Paulsen F, Föge M, Thale A, Tillmann B and Mentlein R. Absorption of lipophilic substances from tear fluid by the epithelium of the nasolacrimal ducts. Invest Ophthalmol
Vis Sci Vol. 43, 2002, S. 3137-3143
Performance to date in the supervision of doctorates
F. Paulsen is successfully active in different areas of basic research at the ocular surface
and the lacrimal apparatus. He has a strong expertise in the understanding of tear film dynamics and innate immune mechanisms of the ocular surface and tear film. He has been
member of the Dry eye Workshop Study (DEWS) group (International board of 60 scientists)
that published 2007 the Dry Eye Workshop study report and of the Meibomian Gland Workshop group (International board of 40 scientists) that published 2011 the Meibomian Gland
Dysfunction Workshop report. He is a worldwide leading expert in the understanding of dry
eye syndrome pathophysiology as well as tear film physiology, tear film dynamics and tear
outflow mechanisms. These activities are the basis for the supervision of so far successfully
completed Dr. med./Dr. med. dent. Theses.
Finished habilitation theses:
3
Ongoing habilitation theses:
3
Finished Dr. med./Dr. med. dent. doctorates: 16
Ongoing Dr. med./Dr. med. dent. doctorates:
12
Ongoing Dr. rer. nat. doctorates:
Finished Diploma theses:
4
3
Members of the Group of Prof. Paulsen received several awards for the work having performed under his supervision: Since 2002 12 Students Awards as well as 15 Research and
Doctoral Awards.
List of dissertations supervised outside the graduate school
2006 Dr. med. Matthias Gebhardt, „Limbaler Ursprung des Pterygiums – Die Bedeutung
des Angiogensefaktors VEGF (Vascular Endothelial Growth Factor) und seiner
Rezeptoren VEGFR-1 und VEGFR-2“ (now Department of Trauma Surgery, Hamburg)
2007 Dr. med. Roman Hirt, „Die ableitenden Tränenwege; eine vergleichende Untersuchung von Hund und Mensch unter Berücksichtigung der epithelialen Muzinproduktion“ (now Department of Otorhinolaryngology, Dessau)
2008 Dr. med. dent. Thies Heye, „Muzinverteilung in gesunder Nasenschleimhaut und bei
Polyposis nasi“ (now established as dentist in Hamburg)
2008 Dr. med. dent. Cordula Keine, „Qualitative und quantitative Untersuchungen von
Muzinen und Trefoil-factor-family (TFF) Peptiden in der Uvula von Patienten mit obstruktivem Schlafapnoesyndrom (OSAS)“ (now working as dentist in Munich)
2009 Dr. med. Anne Jansen, „Der Einfluss von TFF-Peptiden auf die corneale Wundheilung“
2009 Dr. med. Ivonne Minsel, „Somatostatin und Somatostatinrezeptoren im Tränenwegsystem und an der Augenoberfläche“ (now Department of Dermatology, Erfurt)
2009 Dr. med. Christian Kindler, „Nachweis und Funktion der Surfactantproteine A und D
im Tränenapparat, der Augenoberfläche und der Tränenflüssigkeit des Menschen“
(now working in a group practice for dermatology in Berlin)
2010 Dr. med. dent. Andreas Willer, „Nachweis von Muzin im Kehlkopf und Eignung zur
Verwendung als Tumormarker beim Larynxkarzinom“ (now working as dentist in a clinic for oral surgery in Magdeburg)
2010 Dr. med. Sophie Rösler, „Die Bedeutung von Trefoil factor family peptide 3 in der
Pathophysiologie der Arthrose und der septischen Arthritis“ (now working in a peripheral hospital, Department for Internal Medicine in Munich)
2010 Dr. med. Ulrike Hampel, „Relaxin und der Relaxin-like Faktor sowie die Leuzinreichen G-Protein-gekoppelten Rezeptoren 7 und 8 an der Augenoberfläche und im
Tränenapparat“ (now Postdoc in the Department of Anatomy II, FAU Erlangen)