Isabelle FOURNIER 39 ans, mariée, 1 enfant - Laboratoire

Isabelle FOURNIER
Professeur des Universités, 1
39 ans, mariée, 1 enfant
ère
classe, Membre de L’Institut Universitaire de France
 Laboratoire de Spectrométrie de Masse Biologique Fondamentale & Appliquée - EA 4550
er
Bât SN3, 1 étage, Université de Lille 1, F-59655 Villeneuve d’Ascq Cedex
 [email protected]
Diploma
1995-1996
1996-2000
2005
M2 Spectroscopy & Organic Physicochemistry, University Paris 6, Laboratoire de Chimie
Structurale Organique & Biologique, CNRS-UMR 7613, Paris, France
PhD, Speciality Spectroscopy & Organic Physicochemistry, University Paris 6, Laboratoire Chimie
Structurale Organique & Biologique, CNRS-UMR 7613, Paris, France
Habilitation, Laboratoire de Neuroimmunologie des Annélides, FRE-CNRS 2933, University Lille 1,
Lille, France
PROFESSIONAL EXPERIENCE
2000-2001
2001-2002
2002-2003
2003-2009
2009-2011
2011-
Posdoctorate (05/2000-08/2001), Laboratoire "Instrumentelle Analytische Chemie", Pr. M.Karas,
University J. W. Goethe de Frankfurt, Germany
Posdoctorate (09/2001-09/2002), Laboratoire de Neuroimmunologie des Annélides, CNRS-UMR
8017, University Lille1, France
Assistant Professor (10/2002-01/2003), Laboratoire de Neuroimmunologie des Annélides, CNRSUMR 8017, University Lille 1, France
Associate Professor, Laboratoire de Neuroimmunologie des Annélides, CNRS-UMR 8017, University
Lille 1, France
Professor
st
1 grade Professor
PRICES & DISTINCTIONS
2009
20092011
Junior Member Institut Universitaire de France
Excellent Scientific Prime
Great Price Special of Science, Agriculture and Art Societyof Lille
RESPONSABILITIES
2004-
2007-2008
2007-2009
2009-2011
20102011
2012
2012
Group Leader MALDI Imaging Team at Laboratoire de Spectrométrie de Masse Biologique
Fondamentale & Appliquée, Université Lille 1. Starting Grant 2004 for team creation, AERES
Notation A
Member of Scientific Council University Lille 1
Nominated member CNU (National Committee University) section N°68
Nominated member Parity Technique Committee (CTP) University Lille 1
Assistant Director of Laboratoire de Spectrométrie de Masse Biologique Fondamentale et
Appliquée
Assistant Director of Federative Research Institute IFR 147
Member of Scientific Council University Lille 1
Responsible Imaging Platform & management committee member, SIRIC ONCOLILLE, National
Institute of Cancer, Integrated Research in Cancer Site (SIRIC)
TEATCHING RESPONSABILITES
2003-2009
2005-2009
2005-2009
200920102010-
Responsible Teaching Unit in the Professional Master of Proteomics
Responsible Teaching Unit in the Research Master in Life Physico-chemistry
Responsible Teaching Unit in the IUP Genomic and Proteomic, M1, S2
Responsible Teaching Unit in the International Master Advanced Spectroscopy in Chemistry, M1, S2,
Spectroscopy for life sciences
Responsible Teaching Unit, Master Biology & Biotechnology, Specialty Genomic & Proteomic,
Proteomics, M2, S3, Mass Spectrometry & M2, S4, Training sessions
Responsible Teaching Unit, Master Biology & Biotechnology, Specialty Genomic & Proteomic, M1,
S2, Proteome Analysis
2010-
Responsible Teaching Unit, Master Biology & Biotechnology, Specialty Health Biology, M1, S2,
Proteins Structural Analysis
SICENTIFIC AKNOWLEDGMENT & EXPERTISES
 Reviewer for international journals
 Expertise
-France: Région Centre, ANRT, Région Ile de France, Canceropôle Ile de France, AERES
-International: Belgium (ARC Wallonie, FNRS), UK (Cancer Research, BBSRC, MSS), Netherlands (Genomic
Initiative), Germany (DFG), Loand (Polish Science Foundation), Canada (FRNTQ)
Management Committee Member of COST Action BM1104, FP7 (2011-2016)
 Editorial of International Journals
-Associated editor for Journal of Clinical Bioinformatics et Journal of Integrated Omics
 Treasurer of the French Society for Mass Spectrometry (09/2007-09/2008)
 Conferences organization
-Scientific committee 25èmes Journées de la Société Française de Spectrométrie de Masse, Grenoble, 8-11
September (2008) ; Scientific Committee SMAP (Mass Spectrometry and Proteomic Analysis) 2009, Dijon, 14-17
September (2009)
 Conference Chair
-Annual Conference French Society for Electrophoresis and Proteomics Analysis (SFEAP) , Saint-Malo, 16-18
October, 2006 ; Conference Mass Spectrometry and Proteomic Analysis SMAP), Dijon, 14-17 September, 2009 ;
Desorption 2010 Conference Seillac, 30 Mai- 3 June, 2010 ; Conference Mass Spectrometry and Proteomic Analysis
SMAP) Avignon, 19-22 September 2011
VALORISATION
 9 international patents, 2 delivered in EU & US
 Co-funding IMABIOTECH Start-Up
SCIENTIFIC PROJECTS
 Coordinator
-Research Medical Foundation, FRM (2002), National Starting Grant ACI « Jeunes Chercheurs et jeunes
Chercheuses » (2004), National Institute for Cancer (2006), National Grants ANR-Program PCV, BIOSPIM (2008),
ANR-Program Blanc, FUN MALDI (2009), ARCIR/FEDER Région Nord-Pas de Calais (2010)
 Project Partner
-ANR-Program PIRIBIO- MASDA EYE (2010), ISAO Internationale Stichting Alzheimer Onderzoek (2010),
KORANET International Cooperation Program with Korea (2010) FP7, Action COST, Mass Spectrometry Imaging:
New Tools for Health Care Research (2011)
RESEARCH THEMATICS
1995-2001
2001-
Fundamental of MALDI desorption/ionization processes
MALDI Mass Spectrometry Imaging: Developments and Application
ONGOING PROJECTS

Developments
-IDENTITI: MALDI MS Imaging developments of strategies for protein identification
-TDXMS: Development of a new strategy for studying proteins conformation at tissue level
-SPIDER-MASS: Development of a system for in vivo Imaging by MS

Applications
-Physiopathological mechanisms of ovarian cancer
-Leech regeneration vs. spinal cord injury of vertebrates
PUBLICATIONS
 64 publications in international peer-reviewed journals, 9 patents, 8 books chapters on invitation, 71 oral
communications among which 51 on invitation
[1]
R. Lemaire, J.C. Tabet, P. Ducoroy, J.B. Hendra, M.Salzet, I. Fournier, Anal. Chem. (2006) 78, 809-819, Solid
Ionic Matrices for Direct Tissue Analysis and MALDI Imaging
[2]
[3]
[4]
[5]
[6]
[7]
R. Lemaire, A. Desmons, J.C. Tabet R. Day, M. Salzet, I. Fournier, J. Prot. Res. (2007), 6, 1295-1305,Direct
Analysis and MALDI Imaging of Formalin Fixed, Paraffin Embedded Tissue Sections
R. Lemaire, J. Stauber, M. Wisztorski, C. Van Camp, A. Desmons, M. Deschamps, G. Proess, I. Rudlof, A. S.
Woods, R. Day, M. Salzet, I. Fournier, J. Prot. Res. (2007), 6, 2057-2067, TAG-MASS: Specific Molecular
Imaging of Transcriptome and Proteome by Mass Spectrometry Based on Photocleavable Tag
R. Lemaire, S. Aït-Menguellet, J. Stauber, V. Marchaudon, J-P. Lucot, P. Collinet, M-O. Farine, D. Vinatier, R.
Day, P. Ducoroy, M. Salzet, I. Fournier, J. Prot Res. (2007), 6 (11), 4127-4134, Specific MALDI Imaging and
Profiling for Biomarker Hunting and Validation: Fragment of the 11S Proteasome Activator Complex, Reg Alpha
Fragment, Is a New Potential Ovary Cancer Biomarker
J. Stauber, R. Lemaire, J. Franck, D. Bonnel, D. Croix, R. Day, M. Wisztorski, M. Salzet, I. Fournier, J. Prot Res.
(2008), 7(3), 969-978,MALDI Imaging of FFPE Tissues: Application to Model Animals of Parkinson Disease for
Biomarker Hunting
Franck J., Arafah K., Elayed M., Bonnel D., Vergara D., Jacquet A., Vinatier D., Wisztorski M., Day R., Fournier I.,
Salzet M., Mol Cell Proteomics (2009) 8(9), 2023-33, MALDI imaging mass spectrometry: state of the art
technology in clinical proteomics.
Meriaux C., Arafah K., Tasiemski A., Wisztorski M., Bruand J., Wichlacz-Boidin C., Desmons A., Debois D.,
Laprévote O., Brunelle A., Gaasterland T., Macagno E., Fournier I., Salzet M., PLos One (2011), 6(4): e18359,
Multiple Changes in Peptide and Lipid Expression Associated with Regeneration in the Nervous System of the
Medicinal Leech