Quentin Glenadel

Quentin Glenadel
PHD Student at SURCOOF (Dr. Thierry BILLARD)
[email protected]
Experience
PHD Student at SURCOOF (Dr. Thierry BILLARD)
octobre 2014 - Poste actuel (1 mois)
Development of new synthetic routes to fluorinated molecules and application to medical imaging:
- Synthetic methodology: development of new methods and reagents for introducing SCF3 and OCF3
moieties on various organic molecules.
- Syntheses of new fluorinated ligands for diagnosis and treatment of neurodegenerative diseases in PET
imaging (e.g. Alzheimer).
Contact: Thierry Billard (Director of research CNRS): [email protected]
Master Thesis Student at SURCOOF (Pr. Olivier PIVA)
février 2014 - juillet 2014 (6 mois)
Total synthesis of natural product and methodology (metathesis and photochemistry).
Contact: Olivier Piva (Professor): [email protected]
Medicinal chemist at Infinity Pharmaceuticals
juillet 2012 - juin 2013 (1 an)
Through this year, I worked as medicinal chemist. My role was to make analogs which were potent and
selective for a PI3K project.
During this internship, I improved my lab skills. I also developed my knowledge in organic chemistry as well
as in analytical sciences and biology. I used a lot of different analytical instruments. I learned how to organize
my time, my workplace and how to present my results during chemistry meetings.
Contact: Martin Tremblay (Director, Chemistry): [email protected]
Visiting student of Lautens Research Group at University of Toronto
avril 2010 - juin 2010 (3 mois)
I developed a new method of rhodium-catalyzed intermolecular addition of arylboronic acids to
sulfonylacetonitriles (up to 98% yield). This method allows for efficient synthesis of various beta-keto
sulfones which are found to have therapeutic effects (metabolic syndrome and type II diabetes).
The work I have done was published in December 2010 in Organic Letters (see below).
Contact: Mark Lautens (University professor): [email protected]
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Publications
Rhodium(I)-Catalyzed Addition of Arylboronic Acids to (Benzyl-/Arylsulfonyl)acetonitriles: Efficient
Synthesis of (Z)-beta-Sulfonylvinylamines and beta-Keto Sulfones
Organic Letters 13 décembre 2010
Auteur(s) : Quentin Glenadel, Gavin Chit Tsui, Ph.D., Chan Lau, Mark Lautens
An efficient rhodium(I)-catalyzed addition of arylboronic acids to (benzyl-/arylsulfonyl)acetonitrile is
described. Novel beta-sulfonylvinylamine products are formed in a stereoselective fashion (Z-alkene). Upon
hydrolysis, useful beta-keto sulfones are obtained with a broad scope of aryl and sulfonyl substituents.
Languages
English
French
Spanish
(Capacité professionnelle complète)
(Bilingue ou langue natale)
(Notions)
Education
Université Claude Bernard Lyon 1
Master's degree, Organic chemistry, 2013 - 2014
Grade: Top of the class with distinction (mention très bien)
Ecole supérieure de Chimie Physique Electronique de Lyon / CPE Lyon
Master’s degree in Engineering + Bachelor's degree, Organic Chemistry, 2010 - 2014
Grade: Second best student (CPE scientist award)
Université Paul Sabatier (Toulouse III)
2 years technical degree, Chemistry, 2010 - 2012
Grade: Top of the class with honours (mention bien)
Skills & Expertise
Organic Chemistry
Organic Synthesis
Analytical Chemistry
Pharmaceutical Research
Medicinal Chemistry
Drug Design
NMR
LC-MS
Drug Discovery
Synthetic Organic Chemistry
HPLC
Lead Change
Chromatography
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Chemistry
Mass Spectrometry
Purification
Microsoft Office
ChemDraw
Electronic Lab Notebooks
Honors and Awards
CPE scientist award - Silver medal
CPE Lyon
avril 2012
Award for the second best student on semesters 5, 6 and 7 all scientific matters
The GlaxoSmithKline Certificate
GSK
novembre 2011
Year 3 (semesters 5 and 6) GSK prize for best overall performance in organic chemistry.
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Quentin Glenadel
PHD Student at SURCOOF (Dr. Thierry BILLARD)
[email protected]
Contact Quentin on LinkedIn
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