english version

Chemistry department
LESSON PLAN
MASTER 1 CHEMISTRY
2015-2016
2
Summary
Master 1 chemistry.................................................................................................................................. 3
SEMESTER 1 ......................................................................................................................................... 4
SEMESTER 2 ......................................................................................................................................... 9
3
Master 1 chemistry
Lectures in French and english
Goals

Complete the general knowledge of chemistry

Deepen more specific disciplines in the field of
biomolecules, polymers and analysis
General organization
In the first semester students take a core curriculum to enable them to strengthen and deepen
their knowledge.
In the second half, they must choose one of three specialities :

Biomolecules

Polymer materials and energy

Analysis
Compulsory training period of 3 to 5 months, taking place in a laboratory or company, allows
students to make contact with industry and research in order to choose the best orientation to a
Master 2 research or professionnal.
Prerequisites
Students must be licensed
Responsible
Jacques Uziel ([email protected], 01 34 25 70 44)
Secretariat
Laetitia Buton ([email protected], 01 34 25 70 34)
Registration form available at the office or downloadable :
www.u-cergy.fr/fr/ufr-sciences-et-techniques/departement-de-chimie/formations/m1-chimie.html
4
Lessons
UE
Title
UE1
Analyzes and
separations
Structures et
catalysis
Synthesis and
properties
Labs
UE2
UE3
UE4
ECTS Lesson Tutorial Lab
8
35h
35h
-
8
35h
35h
-
8
35h
35h
-
6
-
-
30h
5
UE1 Analyses et séparations—Spectroscopies
Enseignant :
Contenu
UE1 Analyzes and separations—NMR
Teacher : G. DOSSEH
Contents
I-Reminders
Structure determination by 1D NMR high resolution liquid phase
II-Principles of NMR
Quantum bases of NMR spectroscopy
Classical approximation : vector formalism, NMR Fourier transform
III-Relaxation phenomena and applications
Spin-lattice relaxation and spin-spin relaxation
Measurement of relaxation times
Double resonance and nuclear Overhauser effect
IV-Effects of molecular dynamics on the NMR spectra
V-Some complex experimental method in 1D NMR
Chemical shift reagent
Edition spectra
VI-NMR two-dimensional
Spectra chemical shift correlations
J-resolved
UE1 Analyzes and separations—Separation methods - Chromatography
Teacher : C. VANCAEYZEELE
Contents
I-Principles
II-Qualitative and quantitative analysis
III-Gas chromatography
IV-Liquid chromatography
V-Gas chromatography coupled with mass spectrometry
UE2 Structures and catalysis—Cristallography, chemistry of solid
Teacher :
Contents
I-Symmetry of finite figures
1) Symmetry operations
a) Rotation
b) Reflexion
c) Inversion
6
2) Point groups
a) Definitions-exemples
b) Crystal systems
3) Stereographic projection
II-Symmetry of infinite periodical figures
1) Translation
2) Helical axes
3) Translatory mirrors
III-Determination of crystal structures
1) Definitions
2) Spacial groups
3) X-ray diffraction
a) Basic concepts
b) Intensity diffracted by a centrosymmetric structure
c) Systematic extinctions
i) Primary extinctions
ii) Secondary extinctions
UE2 S1 Structures and catalysis—Orbital-approche
Teacher : G. SINI
Contents
I-Orbital-approach in chemistry
Study of molecular electronic structure by means of theoretical models : Hartree-Fock
method, correlation energy, configuration interaction, Koopmans’ theorem, Pauli principle,
Slater determinants, H2 molecule by valence bond- and molecular orbital theories, coulomb
and exchange integrals.
Woodward-Hoffmann rules : cyclo-additions, electrocyclic, and sigmatropic reactions.
II-Introduction to molecular modelling
Introduction to ab-initio and semi-empirical methods, molecular mechanics
UE2 S1 Structures et catalyse—Bioorganique
Enseignant
Contenu
7
UE2 Structures and catalysis—Heterogeneous catalysis
Teacher : N. LINDER
Contents (lectures in english)
1) Introduction to catalysis (reminders—organometallic chemistry)
2) Heterogeneous catalysts
a) types
b) synthesis
c) characterization
3) Catalytic cycle—effects with respect to catalyst, surface and reactant
a) Paul Sabatier principle
b) Molecular adsorption at the surface and surface reactions
4) Catalytic processes
a) Craquage
b) Fischer-Tropsch
c) Ziegler Natta
UE3 Synthesis and properties—Macromolecular chemistry
Teacher : C. PLESSE
Contents
I-Reminder : free radical polymerization
Mechanism
Rate expressions
Steady-state assumption
II-Emulsion polymerization
Description of process
Quantitative aspects
Applications
III-Free radical copolymerization
Interest
Equations of composition
Instantaneous copolymer composition curves
Considerations on reactivity
IV-Living free-radical polymerization
Stable free radical polymerization (SFRP)
Atom transfert radical polymerization (ATRP)
Radical addition-fragmentation transfert (RAFT)
V-Industrial polymers and radical polymerization
UE3 Synthesis and properties—Physico-chemistry of interfaces
Teacher : O. FICHET
Contents
I-The gas-solid interface : Chemisorption, physisorption,adsorption isotherms of Langmuir,
8
BET, heterogeneous catalysis
II-The liquid-gas interface : Surface tension, Young-Laplace’s equation, Kelvin’s equation,
Dupres’s equation, Surface excess—Applications : adsorption of solutes, bubbles, drops,
capillarity, contact angle, …
III-The liquid-liquid interface : Micelles (thermodynamic behavior,critical micellar
concentration (CMC), …), Emulsion : Hydrophilic-Lipophilic Balance (HLB), Ternary
diagrams
UE3 Synthèses et propriétés—Grandes méthodes de synthèse I
Enseignant
Contenu
UE4 Tutorials—Organic chemistry and NMR
Responsible : E. CHELAIN
Contents
1) Synthesis of silyl ether: kinetic enolate—thermodynamic enolate
2) Synthesis of Dimedone
3) Asymmetric synthesis : Reversal of stereogenic center on the (-)-menthol
4) NMR
UE4 Tutorials—Computer modelling
Responsible : G. SINI
Contents
Activated dienophiles in Diels-Alder cycloadditions, solvent effects on tautomeric equilibria,
stereochemistry of nucleophilic addition to norcamphor and camphor
UE4 Tutorials—Cristallographie, UV et IR
Responsable :
Contenu
1)
UE4 S1 Travaux pratiques—Analyse
Responsable :
Contenu
1)
9
Lessons
UE
Title
ECTS Lesson Tutorials Lab
UE1
Synthesis II
6
30h
30h
-
UE2
Practices and individual
work
6
-
5h
35h
UE3
English
3
-
40h
-
UE4
Professionnal immersion
(3-5 months)
5
-
-
-
Teaching units to choose from
UE5
Teaching Analysis
10
40h
40h
-
or UE5
Teaching Biomolecules
10
40h
40h
-
or UE5
Teaching Polymer materials and
energy
10
40h
40h
-
10
UE1 Synthèses II—Grandes méthodes de synthèse II
Enseignant :
Contenu
UE1 Synthèses II—Synthèse macromoléculaire
Enseignant :
Contenu
UE1 Synthèses II—Electrochimie appliquée
Enseignant :
Contenu
UE2 Travaux pratiques et individuels—Bibliographie
Enseignant :
Contenu
UE2 Travaux pratiques et individuels—Travaux pratiques Analyse
Responsable :
Contenu
UE2 Practices and individual work—Biomolecules tutorials
Responsible : E. CHELAIN
Contents
Synthesis of chromanone
11
UE2 Practices and individual work—Lab Polymer materials and energy
Responsible : C. PLESSE
Contents
TP 1 : Synthesis of Electroactive polymer actuator
TP 2 : Emulsion polymerization
TP 3 : Free-radical copolymerization
TP 4 : Electropolymerization of conducting polymers
TP 5 : Cationic polymerization
TP 6 : Polymer analysis : Dynamic Scanning Calorimetry (DSC) and Steric Exclusion
Chromatography ( SEC)
TP 7 : Synthesis of Polyurethane foams
UE3 Anglais
Enseignant :
Contenu
UE4 Immersion professionnelle 3-5 mois
Enseignement analyse
UE5 Enseignement analyse—Chimie analytique environnementale
Enseignant :
Contenu
UE5 Enseignement analyse—Méthodes électrochimiques
Enseignant :
Contenu
UE5 teaching Analysis—Separation technics
Enseignant : C. VANCAEYZEELE
Contenu
I-Ion chromatography
1) Method
12
2) Ion exchange principle
3) Ion exchanger
4) Mechanisms
5) Detection
6) Examples
II-Ion pair chromatography
1) Ionisable compounds
2) Chromatographic systems
3) Mechanisms
4) Comparison with ion exchange chromatography
5) Examples
UE5 Enseignement analyse—Mathématiques appliquées
Enseignant :
Contenu
UE5 Enseignement analyse—Instrumentation analytique
Enseignant :
Contenu
Enseignement Biomolécules
UE5 Enseignement biomolécules—De l’acide aminé au peptide
Enseignant :
Contenu
UE5 Enseignement biomolécules—Stratégie de synthèse orientée biomolécule
Enseignant :
Contenu
13
UE5 Teaching biomolecules—Applied Heterocyclic chemistry
Teacher : J. PYTKOWICZ
Contents
I. Introduction
1) Definitions
2) Nomenclature
3) Generalities
II. 3 or 4 membered ring Heterocycles
III.
5 membered ring Heterocycles: synthesis and generalities
1) Generalities
2) Synthetic strategies
3) Hinsberg’s synthesis
4) Paal-Knorr’s synthesis
5) Furan specific syntheses
6) Pyrrole specific syntheses
7) Thiophene specific syntheses
IV. 5 membered ring Heterocycles : chemical properties
1) Aromaticity
2) Heterocycle polarisation
3) NMR data
V. 5 membered ring Heterocycles: pyrrole reactivity
1) Acidity/basicity
2) SEAr reactions
3) Other reactions
VI. 5 membered ring Heterocycles: réactivité du furane
1) Basicity
2) SEAr reactions
3) Other reactions
VII. 5 membered ring Heterocycles: réactivité du thiophène
1) Basicity
2) SEAr reactions
3) Other reactions
VIII. 6 membered ring Heterocycles: chimie des pyridines
1) Generalities
2) Synthetic methodologies
IX. 6 membered ring Heterocycles: réactivité des pyridines
1) SEAr reactions
2) Pyridines Nucleophilic Substitution
3) Chemistry of anions derived from pyridine
4) Pyridiniums salts alkylation : Comins reactions
X. Indolic heterocycles
1) Generalities
2) Synthetic methodologies
XI. Indoles Reactivity
1) SEAr reaction
2) Mannich reactions
3) Reactivity towards nucleophiles
14
UE5 Enseignement biomolécules—Synthèse asymétrique incluant celle des acides aminés
Enseignant :
Contenu
Enseignement Matériaux polymères et énergie
UE5 Enseignement matériaux polymères et énergie—Polymère en solution
Enseignant :
Contenu
UE5 Teaching Polymer materials and energy—Polymer mechanical properties
Teacher : C. VANCAEYZEELE
Contents
I-Notions on viscoelasticity of polymer materials
II-Mechanical models
III-Time-temperature superposition
IV-Dynamic mechanical analysis
UE5 Enseignement matériaux polymères et énergie—Sol-gel
Enseignant :
Contenu
UE5 Enseignement matériaux polymères et énergie—Polymères conjugués
Enseignant :
Contenu
UE5 Enseignement matériaux polymères et énergie—Conductions dans les polymères
Enseignant :
Contenu
15
UE5 Enseignement matériaux polymères et énergie—Mélange de polymères
Enseignant :
Contenu