for the development of biotechnologies
Transcription
for the development of biotechnologies
CAPBIOTEK, the regional initiative for the development of biotechnologies in Bretagne The goals Bioservices directory • To assemble the regional biotech actors under a common banner. This catalog of bioservices attempts to list all the service providers along the value chain that play a role in rapidly moving your molecule of interest from discovery to market. • To promote excellence in biotechnology and highlight the region’s strengths: convergence between ICT and biotechnologies, as well as specialized know-how in plant and animal production. • To nurture cross-fertilization among different fields of biotechnology (healthcare, cosmetics, agri-food industries). This directory was produced by CRITT Santé Bretagne, the regional tech transfer center for health, medical devices, nutrition and biotech. It coordinated this directory and is your primary contact for further information. CRITT Santé Bretagne is a not-for-profit organization promoting co-operation between research units and companies involved in health-related R&D. Contact: Anne-Claude LEFEBVRE CRITT Santé Bretagne 2 avenue du Pr. Léon Bernard CS 34317 35043 RENNES Cedex Tel. +33 (0)2 23 23 45 81 Fax: +33 (0)2 23 23 45 86 [email protected] www.critt-sante.fr Bretagne: a strong track record in R&D Bretagne: a wide range of bioservices • More than 2800 researchers in the public domain: - 5th at national level - 4 universities, more than 20 «grandes écoles», the major national research organizations (CNRS, Inra, Inserm, etc.) - Ranked 5th nationally in terms of scientific publication and patent submission • More than 50 companies • More than 4700 researchers in the private sector with more than 700 M€ invested in R&D (OST 2008 report) • More than 20 technical core facilities • Over 150 M€ economic activity • Bioservices for the human health, cosmetics, agriculture and energy industries • Strong and growing SME culture ensuring personalized service for our R&D clients and fueling industry growth (CRITT Santé Bretagne) From screening and characterization, or market research and patent protection, to clinical studies and regulatory know-how, Bretagne has the bioservice you need! ABC TEXTURE ACTILAIT ADICEA ADRIA AGRIMER AGRIVAL AGROBIO ALGIEPLUS ANAXIMANDRE ANIMAL FACILITY ANSES ARCHIMEX ARIST ARMOR PROTEINES BIODIMAR BIOPREDIC INTERNATIONAL BIOPREV BIOTRIAL C.RIS PHARMA CABINET LE GUEN MAILLET CABINET VIDON CAP BLEU COMMUNICATION CAPINOV CAPSUGEL CAREF CBB DEVELOPPEMENT CCPA CERNh CEVA CIC-INSERM 0203 CIC-IT 804 CRLCC CTPA DNA MICROARRAY EFFISCIENCE EUROSAFE GIREX SASU H2P2 PAGE N° TECHNICAL CORE FACILITY TECHNOLOGICAL CENTER ENTERPRISE MARKETING REGULATORY & REGISTRATION FORMULATION VALIDATION CHARACTERIZATION INTELLECTUAL PROPERTY SCREENING BIOPRODUCTION MARKET RESEARCH Name of the structure 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 PAGE N° HITEX ICIBIO ID.MER IDHESA IMPACCELL INNOVA PROTEOMICS INPI INRA ANIMAL FEED STATION IPL SANTE IRMA KORILOG LABOFARM LABORATOIRES ADITEC LABORATOIRES D’ARMOR LAREAL LEHA LRBEVA NUTRITION MAZAL PHARMACEUTIQUE MICROMER MRIC NUTRAVERIS ONIS PIXEL POLARIS POLYMARIS BIOTECHNOLOGY PRISM PROCLAIM PRODIABIO SAFECOS SCIENCES ET MER SEADEV FERMENSYS SEQUENCING GENOTYPING STEPP BRETAGNE SYNANOVECT VEGENOV VOISIN CONSULTING XENOBLIS XENOPUS PAGE N° TECHNICAL CORE FACILITY TECHNOLOGICAL CENTER ENTERPRISE MARKETING REGULATORY & REGISTRATION FORMULATION VALIDATION CHARACTERIZATION INTELLECTUAL PROPERTY SCREENING BIOPRODUCTION MARKET RESEARCH Name of the structure 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 Your guide to understanding the Bretagne value chain Legend These icons represent the different business sectors Human health Animal health Plant health Cosmetics Agri - food industries Environment/energy MARKET RESEARCH BIOPRODUCTION Biosynthesis Industrial biotechnologies Extraction Purification SCREENING Sourcing In vitro In situ In vivo INTELLECTUAL PROPERTY CHARACTERIZATION Physical and chemical attributes Efficacy Target identification Lead optimization Toxicology and toxicokinetic profiling Preclinical studies VALIDATION In vivo tests Technological optimization Field trials Clinical investigations FORMULATION Pharmaceutical formulation Encapsulation Rheological measurement Adjuvant – excipient REGULATORY SUPPORT AND REGISTRATION Quality assurance Consulting MARKETING SERVICES Promotion Commercial Communication ABC TEXTURE MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services ABC Texture is a specialist co-contractor for the formulation of beauty products. We help you take high-quality, innovative products to market. Thanks to our expertise in experiential marketing, ABC Texture truly focuses on a new dimension in service provision to the cosmetics industry. After an initial brief, we work with you to define your product's characteristics, from its texture and residual film properties through to ease of application and absorption time. The products formulated by our engineers undergo rigorous quality controls and are tested to ensure their microbiological characteristics, safety, stability and efficacy, and include: • Microbiological tests • Innocuous tests • Stability tests • Efficacy tests TYPE OF STRUCTURE ENTERPRISE Keywords TECHNOLOGICAL CENTER formulation, cosmetics TECHNICAL CORE FACILITY ESTABLISHED IN 2004 Contact Louisette BOURDIN BUSINESS SECTOR ZAC La Ville es Passant II Rue Isaac Newton 35800 DINARD FRANCE Tel. +33(0)2 99 20 03 63 Fax: +33(0)2 99 19 52 20 [email protected] www.abctexture.com 6 ACTILAIT DELEGATION FOR WESTERN FRANCE MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services Actilait’s main activity is the analysis, optimization, testing and promotion of dairy products, whether produced on the farm, by small businesses or by multinationals. Our expertise and areas of activity include research in the public interest (to improve knowledge of dairy products and develop specific tools) and contract services (testing, consultancy, training, expert analysis, audits, etc.). The Western France satellite of Actilait includes: • A biological resource center which proposes: (i) isolation, identification and characterization of various flora (including pathogenic and spoilage strains), (ii) Long-term storage of biological material (bacteria, yeasts, phages, complete ecosystems, etc.) entrusted to us by third parties, with over 2000 strains at present and (iii) expertise in the field of lactic acid bacteria bacteriophages (private collection of 200 phages). • A Food safety team with expertise in the prevention and control of pathogenic risks and crisis management (hygiene). TYPE OF STRUCTURE Keywords ENTERPRISE TECHNOLOGICAL CENTER dairy products, microbiology, isolation, bacteriophages of lactic acid bacteria, microbial libraries, consulting, hygiene TECHNICAL CORE FACILITY ESTABLISHED IN 1981 Contact Jean-René KERJEAN BUSINESS SECTOR BP 50915 35009 RENNES CEDEX FRANCE Tel. +33(0)2 23 48 55 88 Fax: +33(0)2 23 48 55 89 [email protected] www.actilait.com 7 ADICEA MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services The ADICEA analytical and development laboratory provides physicalchemical analysis services to the agrifood, nutraceutical and cosmetics industries. We provide our customers with the benefit of our skills (notably in the field of oils and fats) and day-to-day project support in the following areas: nutritional assessments, quality control, product and process development, etc. ADICEA also offers expert services in the enzymatic synthesis of lipid esters and derivatives for applications in food products or cosmetics. Our know-how enables us to meet our customers' needs and provide fully confidential advice. TYPE OF STRUCTURE Keywords ENTERPRISE analytical services, development services, consultancy, lipid, quality control, stability testing, formulation, enzymatic synthesis TECHNOLOGICAL CENTER TECHNICAL CORE FACILITY Contact Philippe GUEGAN ESTABLISHED IN 2002 BUSINESS SECTOR Parc d'activités Coglais Saint Eustache 35460 SAINT ETIENNE EN COGLES FRANCE Tel. +33(0)2 99 18 58 59 Fax: +33(0)2 99 18 55 22 [email protected] 8 ADRIA DEVELOPPEMENT MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services ADRIA, the Association for R&D and Innovation in the Agrifood Industry, has been providing product support to Bretagne's agrifood industry for over 35 years. Our activities include: • Research on food safety and preservation • Product innovation: formulation, nutritional and functional analyses • Technology consultancy • Regulatory intelligence, scientific and technical document bases • Intercompany training Our resources: • A microbiology and formulation lab • A technical suite with pilot equipment TYPE OF STRUCTURE • A training room • A large document base ENTERPRISE TECHNOLOGICAL CENTER TECHNICAL CORE FACILITY Keywords consultancy, research, training, agrifood, innovation ESTABLISHED IN 1975 Contact Jean-Robert GEOFFROY BUSINESS SECTOR Créac’h Gwen 29196 QUIMPER FRANCE Tel. +33(0)2 98 10 18 18 Fax: +33(0)2 98 10 18 99 [email protected] www.adria.tm.fr 9 AGRIMER MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION Description of services REGULATORY & REGISTRATION Agrimer is an industry leader in the harvesting, transformation and exploitation of marine resources. Thanks to full integration of a wide range of processes for extracting marine-derived ingredients, Agrimer sells raw materials and formulated products in bulk or individually packaged for your brand. Agrimer is a preferred supplier of thalassotherapy centers and spas. MARKETING The company offers access to several processes and services including: VALIDATION FORMULATION • Optimization of drying conditions and maintenance of the seaweed's natural qualities. Shredding, sizing and micronization of dried seaweed (from a few centimeters down to the micron scale) • Dry formulations: special equipment for handling powder products, from mixing through to custom packaging (sachets, jars, 30 g to 25 kg bags, etc.) • Liquid formulations: extraction, filter sterilization, mixing, custom packaging from 3 ml to 20 l volumes TYPE OF STRUCTURE • Cosmetic processes: dual-stage reverse osmosis water treatment unit, vacuum turbo-emulsifier, custom packaging in all formats (tubes, jars, bottle, etc.) ENTERPRISE TECHNOLOGICAL CENTER TECHNICAL CORE FACILITY Keywords seaweed, custom manufacturing, ingredients ESTABLISHED IN 1992 Contact André PRIGENT BUSINESS SECTOR Prat Menan 29880 PLOUGUERNEAU FRANCE Tel. +33(0)2 98 04 54 11 Fax: +33(0)2 98 04 55 15 [email protected] www.agrimer.com 10 AGRIVAL MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services Agrival is a specialist in the exploitation of vegetable co-products as food ingredients and active compounds in human health, e.g. glucosinolates from cauliflower, polyphenols from artichoke, sulforaphane from broccoli, quercetin from onion, lentinan from shiitake mushrooms, lycopene from tomato, etc. Custom extraction for other plants (seaweeds, fruits, cereals, aromatic herbs, etc.) is also available for our clients. The laboratory transforms the raw materials into water-soluble powder for use in a variety of different industries (e.g. pharmaceutical, cosmetics, and food supplement). Keywords TYPE OF STRUCTURE nutraceuticals, dietetics, cosmetics, aqueous and solvent-free extraction, natural, organic ENTERPRISE TECHNOLOGICAL CENTER Contact TECHNICAL CORE FACILITY Olivier MOAL ESTABLISHED IN 2007 Kerisnel 29250 SAINT POL DE LEON FRANCE Tel. +33(0)2 98 15 84 95 Fax: +33(0)2 98 15 84 95 [email protected] BUSINESS SECTOR 11 AGROBIO MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services Agrobio offers its customers full-service microbiological, physical and chemical analysis and testing. The laboratory manages sample collection and logistics, and performs the required analyses in short turnaround times. Agrobio acts as a one-stop shop for all your analytical needs. No need to worry about sample packaging and transport. We provide reliable results and our laboratory works in compliance with industry standards (GLP, COFRAC (ISO 17025)). Keywords TYPE OF STRUCTURE cosmetics, nutraceuticals, efficacy testing, cell cytotoxicity, bioavailability, environmental testing ENTERPRISE TECHNOLOGICAL CENTER Contact TECHNICAL CORE FACILITY Henri LEBON ESTABLISHED IN 2005 BUSINESS SECTOR ZAC des 3 Marches 3 impasse de la Jonchée 35132 VEZIN LE COQUET FRANCE Tel. +33(0)2 99 14 70 50 Fax: +33(0)2 99 14 70 51 [email protected] www.laboratoiresagrobio.fr 12 ALGIEPLUS MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services The Algieplus research center is comprised of two units: • A plant biotechnology laboratory which develops new preventive phytopharmaceutical tools. These reduce the need for conventional pesticide treatments by using long-acting natural compounds with an environmentally friendly toxicological profile. • A technical testing station for trialling various solutions for screening and exploiting waste marine biomass, for use by local authorities. Keywords marine biomass, crop protection, fertilizers, pesticides TYPE OF STRUCTURE Contact ENTERPRISE TECHNOLOGICAL CENTER TECHNICAL CORE FACILITY ESTABLISHED IN 2007 Bruno JACOB Espace Entreprises ZA de Kérantour Nord 22740 PLEUDANIEL FRANCE Tel. +33(0)2 96 20 48 41 Fax: +33(0)2 96 22 01 24 [email protected] www.algieplus.com BUSINESS SECTOR 13 ANAXIMANDRE MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION Description of services Anaximandre is a multimedia communications and ICT engineering agency that specializes in the development of information systems and software as a service for public- and private-sector stakeholders in biotechnology. REGULATORY & REGISTRATION Anaximandre also develops applications in bioinformatics and molecular modelling and performs research on the modelling of biological processes. MARKETING Our services include: • Scientific and technical communication (multimedia, internet, publishing, information graphics, computer-generated images, etc.) • Scientific and technical benchmarking for local authorities and European Union projects • Document management (literature searching, documentation) • Scientific review and audit (reports, competitive intelligence) • Exhibition stand design and logistics TYPE OF STRUCTURE ENTERPRISE Keywords TECHNOLOGICAL CENTRE multimedia, corporate communication, publishing, open source, SaaS TECHNICAL CORE FACILITY ESTABLISHED IN 1998 Contact Guy MORDRET BUSINESS SECTOR Parc d’Innovation de Mescoat 29000 LANDERNEAU FRANCE Tel. +33(0)2 98 30 35 15 Fax: +33(0)2 98 30 32 65 [email protected] www.anaximandre.com 14 informatics, bioinformatics, ANIMAL FACILITY UNIVERSITY OF WESTERN BRITTANY MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services The facility houses animal models for use in in vivo drug testing. The available models relate to human Β-lymphoid diseases (lymphoma, chronic lymphocytic leukaemia) but custom development of animal models is possible (e.g. for colon cancer). The following services are available: • Cancer drug screening • Syngeneic models, subcutaneous (SC), intraperitoneal (IP) intravenous (IV) xenografts (human tumours) and orthotopic grafts or • Toxicity testing • Per os, SC, IP, SC, IV and intramuscular treatment administration • Animal monitoring • Collection of blood and/or tissue samples TYPE OF STRUCTURE Keywords ENTERPRISE TECHNOLOGICAL CENTER BSL2 animal facility, murine models, xenograft, toxicity, leukaemia, lymphoma, cancer TECHNICAL CORE FACILITY Contact ESTABLISHED IN 2009 Séverine LOISEL BUSINESS SECTOR 22 rue Camille Desmoulins CS 93837 29238 BREST CEDEX 3 FRANCE Tel. +33(0)2 98 01 81 52 Fax: +33(0)2 98 01 81 52 [email protected] www.univ-brest.fr/index.php?page=affiche_composante&object=animalerie 15 ANSES LABORATORY FOR THE RESEARCH AND STUDY OF VETERINARY MEDICINAL PRODUCTS AND DISINFECTANTS MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION Description of services REGULATORY & REGISTRATION As a reference laboratory for veterinary medicinal product residues and antimicrobial resistance, it participates in the surveillance and inspection processes associated with these health risks. It helps develop standards for methods to determine the effectiveness of disinfectants and also contributes to the evaluation of biocidal products in Europe. MARKETING The laboratory proposes the following services: VALIDATION FORMULATION • Veterinary drug residue analysis • Pharmacokinetic and toxicokinetic studies • In vitro and in vivo toxicology testing • Antimicrobial assays (bactericidal and virucidal agents), screening for resistance genes TYPE OF STRUCTURE Keywords ENTERPRISE veterinary drugs, food/feed contaminants, physical and chemical analysis, bactericidal activity, virucidal activity, genotoxicity, pharmacokinetics, toxicokinetics TECHNOLOGICAL CENTER TECHNICAL CORE FACILITY Contact ESTABLISHED IN 1975 BUSINESS SECTOR Pascal SANDERS BP 90203 35302 FOUGERES FRANCE Tel. +33(0)2 99 94 78 78 Fax: +33(0)2 99 97 78 80 [email protected] crl.fougeres.anses.fr 16 ARCHIMEX MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services Created in 1989, Archimex has built a great expertise in green extraction technologies, innovative, clean (low temperature, no solvent, short extraction time) and protective of raw materials (animal or vegetal biomass) potentials. Archimex provides industrials of various sectors (cosmetics, phytopharmacy, food, feed) with high quality natural extracts and support them in switching from traditional processes with solvents to eco-extraction (from pilot to industrial scale-up). More services: training and documentation. Keywords TYPE OF STRUCTURE natural ingredients, extraction ENTERPRISE Contact TECHNOLOGICAL CENTER TECHNICAL CORE FACILITY ESTABLISHED IN 1989 Elisabeth AUDOUZE Parc d’Innovation de Bretagne Sud CP31 56038 VANNES FRANCE Tel. +33(0)2 97 47 06 00 Fax: +33(0)2 97 47 56 90 [email protected] www.archimex.com BUSINESS SECTOR 17 ARIST BRETAGNE MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY Description of services CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING ARIST Bretagne fosters and supports economic, technical and scientific intelligence activities in Bretagne-based companies and economic stakeholders: • Information management audits and project support for structuring and coordinating an intelligence-based approach • Economic, technical, scientific and regulatory intelligence reports and updates • Advice on brainstorming techniques for stimulating innovation: new product/market matching for fulfilling user needs or resolving technical or organisational problems; product design or re-design • Intellectual property audits (status, needs and practices) • Technical and legal patent analysis for optimal protection of an invention TYPE OF STRUCTURE Keywords ENTERPRISE TECHNOLOGICAL CENTER intellectual property, standards, management, innovation consultancy regulatory affairs, TECHNICAL CORE FACILITY Contact ESTABLISHED IN 1983 BUSINESS SECTOR Alexandre COLOMB Chambre régionale de commerce et d’industrie de Bretagne 1 rue du Général Guillaudot CS 14422 35044 RENNES CEDEX FRANCE Tel. +33(0)2 99 25 41 25 Fax: +33(0)2 99 25 41 10 [email protected] arist.bretagne.cci.fr 18 information ARMOR PROTEINES MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services Armor Proteines, a subsidiary of the Soparind Bongrain Group (one of the world’s leading dairy groups) uses cutting edge and emerging technologies to provide a wide range of functional and nutritional ingredients. Co-developer of new concepts, and a partner in strategic alliances, Armor Proteines is striving to become a world-wide specialist in milk fractionation and producer of value-added dairy ingredients and milk proteins (caseins, serum proteins, biopeptides, whey derivatives and lactose). Keywords ingredients, development, milk, fractionation, nutrition and healthcare, nutritional formulation TYPE OF STRUCTURE ENTERPRISE Contact TECHNOLOGICAL CENTER Dominique MORELLE TECHNICAL CORE FACILITY Le Pont 35460 SAINT BRICE EN COGLES FRANCE Tel. +33(0)2 99 18 52 52 Fax: +33(0)2 99 97 79 91 [email protected] www.armor-proteines.com ESTABLISHED IN 1992 BUSINESS SECTOR 19 BIODIMAR MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION Description of services Biodimar has expertise in the extraction, purification and analysis of biomolecules: FORMULATION • Collection of samples or organisms and supply of biomass or extracts REGULATORY & REGISTRATION • Compound purification MARKETING • Lyophilisation, grinding/shredding, extraction and concentration • Screening for biological activities • Physical chemistry analyses • Antioxidant activity assays • Anti-aging activity assays Our client sectors include pharmaceuticals, cosmetics, blue (marinesourced) and green chemistry, and agrifood. TYPE OF STRUCTURE Keywords ENTERPRISE TECHNOLOGICAL CENTER biomolecules, extraction, purification, sample preparation, analysis, titration, biological screening TECHNICAL CORE FACILITY Contact ESTABLISHED IN 2010 BUSINESS SECTOR Eric DESLANDES Université de Bretagne Occidentale UFR Sciences Techniques Bât. F 6 avenue de Gorgeu 29238 BREST FRANCE Tel. +33(0)2 98 01 66 50 Fax: +33(0)2 98 01 66 50 [email protected] 20 BIOPREDIC INTERNATIONAL MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION Description of services Biopredic International is a worldwide supplier of human and animal primary cells, cell lines and tissues for research, drug discovery, drug development, pharmacology and toxicology. REGULATORY & REGISTRATION MARKETING Keywords HepaRG cells, reagents, toxicology, tissues, organs, fluids, drug assays Contact Christophe CHESNE TYPE OF STRUCTURE ENTERPRISE TECHNOLOGICAL CENTER TECHNICAL CORE FACILITY 8-18 rue du Professeur Jean Pecker Z.A. Atalante Villejean 35000 RENNES FRANCE Tel. +33(0)2 99 14 36 14 Fax: +33(0)2 99 54 44 72 [email protected] www.biopredic.com ESTABLISHED IN 1993 BUSINESS SECTOR 21 BIOPREV MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services Bioprev has an expertise in fermentation processes: • Development of fermentation processes for the agrifood industry • Consultancy on strain selection for lactic ferments, yeasts and molds (mesophiles, thermophiles, starter flora, flora for aromatization and ripening, etc.) • Definition of lab-scale through to industrial-scale culture conditions (mixed cultures, probiotic cultures, etc.), and metabolic profiling Keywords fermentation, microbiology, consultancy, agrifood, lactic ferments, mixed cultures, probiotic culture, metabolism, starter flora, flora for aromatization and ripening TYPE OF STRUCTURE ENTERPRISE Contact TECHNOLOGICAL CENTER Jean DELORME TECHNICAL CORE FACILITY ESTABLISHED IN 2004 3 rue du Père Grignon 35000 RENNES FRANCE Tel. +33(0)6 74 38 74 45 Fax: +33(0)2 23 46 72 71 [email protected] BUSINESS SECTOR 22 BIOTRIAL MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services The contract research organization Biotrial performs non-clinical and clinical studies for the pharmaceutical, cosmetic and agrifood industries. Biotrial's services include: • Non-clinical pharmacology • Performance of Phase I clinical pharmacology trials • Data management, biostatistics and medical writing • Management of home-based clinical trials: Phase II and III trials and oncology studies • Core lab: central ECG/MRI reading • QA and regulatory affairs TYPE OF STRUCTURE ENTERPRISE Keywords clinical studies, pharmacology, biostatistics, oncology, patients TECHNOLOGICAL CENTER TECHNICAL CORE FACILITY Contact Jean-Marc GANDON ESTABLISHED IN 1989 BUSINESS SECTOR 7-9 rue Jean Louis Bertrand Technopole Atalante Villejean 35000 RENNES FRANCE Tel. +33(0)2 99 59 91 91 Fax: +33(0)2 99 59 91 99/97 [email protected] www.biotrial.com 23 C.RIS PHARMA MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services C.RIS Pharma is a contract research organization (CRO) which specializes in the preclinical development of drug candidates. It has expertise in the fields of cancer, neurodegenerative disease, metabolic and genetic diseases, agrifood and cosmetics. The CRO has particular expertise in the characterization of active compounds, drug target identification and validation, and toxicological and metabolic studies. C.RIS Pharma can also develop customer-specific assays or cell-based models on request. C.RIS Pharma offers its services to pharmaceutical and biotech companies (efficacy assays, pharmacology and toxicology), the fine chemicals industry (biological activity), agrifood and cosmetics firms (antioxidant properties, allergic properties, efficacy, safety/toxicological studies, etc.). TYPE OF STRUCTURE Keywords ENTERPRISE preclinical development, in vivo, in vitro, identification TECHNOLOGICAL CENTER TECHNICAL CORE FACILITY Contact ESTABLISHED IN 2003 Pierrick AUVRAY BUSINESS SECTOR Parc Technopolitain Atalante Saint-Malo 35400 SAINT-MALO FRANCE Tel. +33(0)2 99 19 69 70 Fax: +33(0)2 23 52 16 41 [email protected] www.c-rispharma.com 24 CABINET LE GUEN MAILLET MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services Cabinet Le Guen Maillet offers the following services: • Intellectual property consultancy • Strategies for protecting research results and inventions • Patent and literature searching • Patent drafting, filing and prosecution in France, Europe and worldwide. • Contract negotiation and drafting: licensing, collaborative R&D and consortium agreements, etc. • Infringement actions • Trademark searches and applications Keywords TYPE OF STRUCTURE patent, invention, trademark, know-how, contract, infringement ENTERPRISE TECHNOLOGICAL CENTER TECHNICAL CORE FACILITY ESTABLISHED IN 1992 BUSINESS SECTOR Contact Denis LE GUEN et Alain MAILLET 5 place Newquay BP 70250 35802 DINARD CEDEX FRANCE Tel. +33(0)2 99 46 55 19 Fax: +33(0)2 99 46 41 80 [email protected] www.leguenmaillet.com 25 CABINET VIDON MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION Description of services Cabinet Vidon offers a range of services and consultancy in the field of intellectual property: patent filing, trademarks, registered designs, software protection and copyright. REGULATORY & REGISTRATION • Drafting collaborative R&D contracts (patent licensing and assignment, know-how transfer, joint research) MARKETING • Intellectual property litigation • Patent searches and surveys, examination of patent validity Keywords intellectual property, patents, trademarks, registered designs, contracts, consultancy, audit, litigation TYPE OF STRUCTURE ENTERPRISE Contact TECHNOLOGICAL CENTER Patrice VIDON TECHNICAL CORE FACILITY 168 rue de Jouannet BP 90333 Technopole Rennes Atalante 35703 RENNES CEDEX 7 FRANCE Tel. +33(0)2 99 38 23 00 Fax: +33(0)2 99 36 02 00 [email protected] www.vidon.com ESTABLISHED IN 1988 BUSINESS SECTOR 26 CAP BLEU COMMUNICATION MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services Cap Bleu Communication offers a range of services and consultancy in the fields of marketing and communication, and specializes in brand creation positioning and image management. Our services include: • Capsentis, a think-tank equipped with tools for performing surveys, identifying trends and generating new methodologies in France and internationally • Project support for new product development, market launch and market access (China, etc.) • A specialized media library for our customers, with over 65,000 photos • Purchasing of advertising space in the specialist press, media plan creation • Web 2.0 • Development of new ICTs TYPE OF STRUCTURE ENTERPRISE Keywords TECHNOLOGICAL CENTER TECHNICAL CORE FACILITY marketing, brand image, innovation, positioning, ICT, consultancy, design, packaging, DTP, nutritional health, cosmetics, communication, business intelligence, international business Contact Evelyne OLLIVIER-LORPHELIN BUSINESS SECTOR Campus de Ker Lann Parc de Lormandière Bât. A Rue Maryse Bastié 35170 BRUZ FRANCE Tel. +33(0)2 99 05 51 01 Fax: +33(0)2 99 05 53 21 [email protected] www.cap-bleu.com 27 CAPINOV MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services Capinov's multidisciplinary and complimentary staff offers a wide range of services to stakeholders in the agricultural, agrifood and environmental sectors. We can meet your needs in terms of analysis, whether you have a routine analytical need, or are searching for a specific area of expertise, technique, or analytical method, or services such as training, consultancy, sampling methods, etc. Capinov is GPL and COFRAC (ISO 17025) labelled. Keywords TYPE OF STRUCTURE consultancy, analysis, effluents, pollutants, contaminants, technology watching, food labelling ENTERPRISE Contact TECHNOLOGICAL CENTER TECHNICAL CORE FACILITY ESTABLISHED IN 1965 Jean-Luc HARDY Z.I. de Lanrinou 29206 LANDERNEAU CEDEX FRANCE Tel. +33(0)2 98 25 30 24 Fax: +33(0)2 98 25 32 74 [email protected] www.capinov.fr BUSINESS SECTOR 28 CAPSUGEL MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION Description of services As a division of Pfizer Inc., Capsugel custom-develops, manufactures and markets gelatine capsules, for the use in drug and dietary supplement applications. REGULATORY & REGISTRATION MARKETING Keywords gelatine capsules, pharmaceuticals, food, delivery systems, nutrition, GMP Contact Thierry LE BOURGEOIS TYPE OF STRUCTURE ENTERPRISE TECHNOLOGICAL CENTER TECHNICAL CORE FACILITY Z.I. Camagnon BP 320 56803 PLOERMEL CEDEX FRANCE Tel. +33(0)2 97 72 10 00 Fax: +33(0)2 97 72 15 00 [email protected] www.capsugel.com ESTABLISHED IN 1995 BUSINESS SECTOR 29 CAREF MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services CAREF is an independent, private-sector R&D laboratory for biopolymer extraction and purification and the elaboration of analytical files for the pharmaceutical industry. CAREF is also involved in pharmaceutical formulation, the validation of analytical control methods, compatibility studies and real-time stability testing. In addition, CAREF provides analytical services for biopolymers (DNA, oligosaccharides, hyaluronic acid, etc.) as well as the routine pharmaceutical quality control (physical-chemical and microbiological testing). Keywords TYPE OF STRUCTURE custom analysis, stability testing, consultancy, formulation, project support, purification ENTERPRISE TECHNOLOGICAL CENTER TECHNICAL CORE FACILITY Contact Michèle RANSON ESTABLISHED IN 1997 BUSINESS SECTOR Z.I de l’Aumaillerie 35133 JAVENE FRANCE Tel. +33(0)2 99 99 37 37 Fax: +33(0)2 99 99 05 36 [email protected] www.javenech.com/laboratory/laboratory.html 30 CBB DEVELOPPEMENT MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services Development of active compounds/ingredients for use in the cosmetics, health food, food supplement, animal feed, food and environment industries: • Technical feasibility and industrial transfer of fermentation-based process for producing polysaccharides for the pharmaceuticals and cosmetics industries • Enzymatic synthesis of fatty acid esters • Development of enzymatic protein hydrolysates for nutritional health markets • Analysis of the fermentation step in the production of animal probiotics • Support for the development of biological products for processing organic material Project engineering in biotechnology and fine chemicals (fermentation, enzyme engineering, extraction, purification and chemical synthesis): TYPE OF STRUCTURE • Scientific intelligence and literature reports • R&D consultancy and strategy ENTERPRISE TECHNOLOGICAL CENTER • Expert technical reports • Feasibility studies • Project management and financial engineering TECHNICAL CORE FACILITY ESTABLISHED IN 1975 Keywords innovation, technology transfer, biotechnology, fine chemicals, fermentation, enzyme engineering, biomolecules, active compounds, ingredients BUSINESS SECTOR Contact Gilbert BLANCHARD 9 rue du Clos Courtel 35700 RENNES FRANCE Tel. +33(0)2 99 38 33 30 Fax: +33(0)2 99 63 76 88 [email protected] www.cbb-developpement.com 31 CCPA MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services CCPA (Conseils et Compétences en Productions Animales) is a service company with over 40 years of experience in the animal health and nutrition sectors. The company's core positioning in these two markets, its professionalism and its broad range of skills enable CCPA to provide optimal project support to its customers in their various business areas. CCPA provides services in: • Chemical and biological testing • Quality and environment • Animal production science • Formulation • Production • Specialist software packages TYPE OF STRUCTURE • Sales and marketing, PR ENTERPRISE TECHNOLOGICAL CENTER TECHNICAL CORE FACILITY Keywords consultancy in animal nutrition and health, chemical and biological testing, premix, adjuvants, nutritional products ESTABLISHED IN 1966 Contact Jean-Jacques BLAIN BUSINESS SECTOR Zone d’activités Nord-Est du Bois de Teillay 35150 JANZE FRANCE Tel. +33(0)2 99 47 53 00 Fax: +33(0)2 99 47 53 92 [email protected] www.ccpa.fr 32 CERNH MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION Description of services The CERNh (Human nutrition research and teaching center) offers a wide range of services for the development of new food products: FORMULATION • Performance of clinical trials in human nutrition REGULATORY & REGISTRATION • Technical and regulatory affairs support on the formulation and packaging of food products or food supplements MARKETING • Health claims support for Afssa and Efsa applications • Literature surveys and reviews CNERh also provides expertise in nutritional health, dietetics and preventive health for the general public (cardiovascular disease, metabolic diseases, diabetes and cancer). Keywords TYPE OF STRUCTURE clinical trials, claims, nutrition, nutraceuticals, consultancy ENTERPRISE TECHNOLOGICAL CENTER Contact TECHNICAL CORE FACILITY Bernard SCHMITT ESTABLISHED IN 1979 BUSINESS SECTOR Centre Hospitalier de Bretagne Sud 27 rue du Docteur Lettry BP 2233 56322 LORIENT CEDEX FRANCE Tel. +33(0)2 97 37 48 07 Fax: +33(0)2 97 37 48 07 [email protected] www.cern-nutrition.fr 33 CEVA MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION Description of services CEVA is the only technical center of its kind in Europe. It supplies services to companies designing and developing industrial products based on marine ingredients (seaweeds, microalgae, marine plants, sea water) and to local authorities confronted with the massive growth or washing-up of seaweed and marine plants. MARKETING Keywords algae, seaweed, microalgae, halophytic plants, marine phanerogames, marine biotechnologies, extraction, purification, characterization, formulation, active compounds, ingredients, algal cultivation, aquaculture TYPE OF STRUCTURE Contact ENTERPRISE Marc DANJON TECHNOLOGICAL CENTER Presqu’île de Pen Lan BP 3 22610 PLEUBIAN FRANCE Tel. +33(0)2 96 22 93 50 Fax: +33(0)2 96 22 84 38 [email protected] www.ceva.fr TECHNICAL CORE FACILITY ESTABLISHED IN 1982 BUSINESS SECTOR 34 CIC-INSERM 0203 MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services The Rennes Clinical Investigation Center (CIC) masters all the professional skills needed to perform clinical research - from first-in-man studies on small groups of healthy subjects or patients to large-scale, multicenter trials in France or across Europe. The Center works closely with nearby research labs and the other CICs in France. The CIC does not place any restrictions on the study theme, design or type of sponsor. Its work covers research in healthy controls and in patients (with or without direct individual benefit) in physiology, pathology, clinical pharmacology, drug trials, genetics, epidemiology, the assessment of diagnostic methods and the identification of prognostic factors. Keywords TYPE OF STRUCTURE clinical studies, clinical pharmacology, drug trials, pharmaco-epidemiology, pharmacogenetics, epidemiology, physiological and pathology studies ENTERPRISE TECHNOLOGICAL CENTER Contact TECHNICAL CORE FACILITY Yves DEUGNIER, Eric BELLISSANT ESTABLISHED IN 2002 BUSINESS SECTOR CHU de Rennes Hôpital de Pontchaillou Centre cardio-pneumologie Pavillon Clémenceau 2 rue Henri Le Guilloux 35033 RENNES CEDEX 9 FRANCE Tel. +33(0)2 99 28 37 15 Fax: +33(0)2 99 28 37 22 [email protected] www.cic-rennes.fr 35 CIC-IT 804 MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services The Rennes CIC-IT 804 Clinical Investigation Center's mission is to innovate and perform clinical research on medical technologies in general, and cardiovascular diagnostic and therapeutic devices in particular. The center is structured around the Signal and Image Processing Laboratory, several clinical departments (cardiology and vascular disease, cardiac, vascular and thoracic surgery, functional investigation, anaesthesia and intensive care, paediatric medicine) and a number of industrial partners. The clinicians, medtech engineers, biostatisticians and clinical research technicians have multidisciplinary skills and offer access to their expertise for: • The clinical evaluation of innovative technologies: design and coordination of multicenter studies, elaboration of specific methodologies and assistance with drafting clinical guidelines TYPE OF STRUCTURE • Technological innovation: identification of clinical needs, definition of new concepts, prototyping support for devices and methods generated in upstream research and assistance with new product development ENTERPRISE TECHNOLOGICAL CENTER TECHNICAL CORE FACILITY Keywords technological innovation, clinical research, medtech, clinical evaluation, cardiovascular ESTABLISHED IN 2008 Contact BUSINESS SECTOR Philippe MABO, Guy CARRAULT Hôpital de Pontchaillou Centre cardio-pneumologie 2 rue Henri Le Guilloux 35033 RENNES CEDEX 9 FRANCE Tel. +33(0)2 99 28 25 09 Fax: +33(0)2 99 28 25 09 [email protected] www.ltsi.univ-rennes1.fr 36 CRLCC DEPARTMENT OF BIOLOGY RENNES MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION Description of services Central laboratory for clinical trials: FORMULATION • Routine laboratory tests (biochemistry, hematology, immunoassays, hemostasis). COFRAC accreditation number: 1-1347 REGULATORY & REGISTRATION • Multiplex ELISA assays MARKETING • Cell culture facilities • RIA Assays • Molecular tests Keywords central laboratory, routine laboratory tests, immunoassays, cell cultures, flow cytometry, human, animal TYPE OF STRUCTURE ENTERPRISE Contact TECHNOLOGICAL CENTER Véronique QUILLIEN TECHNICAL CORE FACILITY BUSINESS SECTOR Department of Biology Centre Eugène Marquis Avenue Bataille Flandres Dunkerque CS 44229 35042 RENNES CEDEX FRANCE Tel. +33(0)2 99 25 31 90 Fax: +33(0)2 99 25 31 64 [email protected] 37 CTPA MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services For over 20 years, the CTPA has been performing field-based validation trials in porcine, bovine and avian species. If you need to evaluate product efficacy and/or safety under "real-life" conditions, the CTPA is your ideal partner for designing, operating and interpreting field trials. The CTPA tests products for the animal health industry (antibiotics, vaccines, antiparasitic agents, anti-inflammatories, etc.) and the agrifood industry (growth factors, probiotics, enzymes, aromas, acidifiers, disinfectants, insecticides, etc.) The CTPA also provides statistical analyses, technology surveys, literature reviews, training sessions, field surveys and advice on tech transfer and funding. TYPE OF STRUCTURE ENTERPRISE Keywords field trials, drug, agrifood industry, pig, poultry, bovine TECHNOLOGICAL CENTER TECHNICAL CORE FACILITY ESTABLISHED IN 1986 BUSINESS SECTOR Contact Alassane KEITA 2 rue Jean Rostand BP 7 22440 PLOUFRAGAN FRANCE Tel. +33(0)2 96 76 61 68 Fax: +33(0)2 96 76 61 69 [email protected] www.zoopole.com 38 DNA MICROARRAY CORE FACILITY MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY Description of services CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING The DNA microarray facility designs and develops coherent methods and tools in functional and integrative genomics (dedicated, high-throughput approaches). Our services include: • Transcriptomics: whole-genome chips (Agilent, Illumina) for studying mRNA expression and microRNA/qPCR assays (Applied Biosystems SybrGreen and Taqman) • Genomics (gene copy number changes and/or genotyping): wholegenome chips (Agilent and Illumina Infinium), qPCR (Applied Biosystems - SybrGreen and Taqman), pyrosequencing (Qiagen) and dedicated chips (Illumina GoldenGate) • Methylomics: CpG Island 244K arrays (Agilent), HumanMethylation27 arrays (Illumina), bisulfite pyrosequencing (Qiagen) and qPCR (Applied Biosystems, SybrGreen and Taqman) TYPE OF STRUCTURE • Statistical and bioinformatics analyses of microarray data: calibration, normalization, differential analysis, biological classification and contextualisation, and integrated functional/genomic annotation (identification of correlations between molecular changes). ENTERPRISE TECHNOLOGICAL CENTER Keywords TECHNICAL CORE FACILITY DNA microarrays, functional and integrative genomics, biomarkers ESTABLISHED IN 2003 Contact Jean MOSSER BUSINESS SECTOR Faculté de Médecine 2 avenue du Pr Léon Bernard CS 34317 35043 RENNES CEDEX FRANCE Tel. +33(0)2 23 23 44 92 Fax: +33(0)2 23 23 44 78 [email protected] ouestgenopuces.univ-rennes1.fr 39 EFFISCIENCE MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services As an expert in applying pharmacology-standard strategies to the fields of biology, dermatology and beauty, Effiscience provides project support for the development of new active compounds and can even assume responsibility for entire product development phases. The efficacy trials offered by Effiscience address a range of cosmetic claims and can be performed separately or as pre-formatted or customdesigned packages. One of Effiscience's unique features is its ability to offer an interface between biochemistry and pharmacology on one hand and histology and immunohistochemistry on the other. Keywords TYPE OF STRUCTURE dermocosmetics, pharmacology, development of active compounds ENTERPRISE TECHNOLOGICAL CENTER Contact TECHNICAL CORE FACILITY Jean-Eric BRANKA ESTABLISHED IN 2003 178 rue de Brest 35000 RENNES FRANCE Tel. +33(0)2 99 33 97 77 Fax: +33(0)2 99 33 97 78 [email protected] www.effiscience.fr BUSINESS SECTOR 40 histology, immunohistochemistry, EUROSAFE MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services Eurosafe is a toxicity testing lab for cosmetic ingredients and cosmetic products. Our laboratory is GLP-compliant, and we perform safety tests on finished products: • Het Cam, NRR and BCOP tests • Tests on Prediskin skin explants and on ingredients: • Genotoxicity tests: AMES, micronucleus, MLA • Phototoxicity: OECD 433 • Skin permeability TYPE OF STRUCTURE Keywords safety tests, safety, microbiology, allergens, genotoxicity tests, ingredients ENTERPRISE TECHNOLOGICAL CENTER TECHNICAL CORE FACILITY Contact Dominique DE JAVEL ESTABLISHED IN 2001 BUSINESS SECTOR Parc d’activités de la Bretèche Bâtiment B1 35760 SAINT-GREGOIRE FRANCE Tel. +33(0)2 99 23 46 46 Fax: +33(0)2 23 25 29 74 [email protected] www.eurosafe.fr 41 GIREX MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services For over 30 years, Girex has acquired extensive experience in the development and production of active compounds and ingredients for the pharmaceutical and nutraceutical markets. Girex's skills in synthesis, plant extraction and purification are based on: • An R&D lab for process design and optimization through to industrial scale-up and the analytical development required for the characterization and quality control of ingredients • Production suites Girex can provide its facilities and expertise for use in (co-)development projects or outsourced manufacturing. Girex is an accredited service provider under France's research tax credit scheme. TYPE OF STRUCTURE Keywords ENTERPRISE TECHNOLOGICAL CENTER fine chemistry, API, plant extraction, purification, natural substances, R&D, pilot, analytical services TECHNICAL CORE FACILITY Contact Bernard LE DOUAIRON BUSINESS SECTOR 11 rue Rontgen 29000 QUIMPER FRANCE Tel. +33(0)2 98 53 54 55 Fax: +33(0)2 98 53 92 72 [email protected] 42 H 2P 2 HIGH-PRECISION HISTOPATHOLOGY MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services This facility offers standard histology lab services plus custom laser microdissection. Applications: • Diagnostics/screening (toxicity, mode of action) on the tissue level • Understanding of physiological and physiopathological mechanisms • Drug target discovery • Analysis of bioactive molecules • Pharmacology, toxicology, pathology • Tissue genomics Keywords TYPE OF STRUCTURE laser microdissection, tissue microarrays, pharmacotoxicology, immunohistochemistry, nucleic acid extraction, amplification ENTERPRISE TECHNOLOGICAL CENTER TECHNICAL CORE FACILITY Contact Alain FAUTREL ESTABLISHED IN 2007 BUSINESS SECTOR Université de Rennes 1 2 avenue du Pr Léon Bernard CS 34317 35043 RENNES CEDEX FRANCE Tel. +33(0)2 23 23 47 95 Fax: +33(0)2 23 23 49 29 [email protected] histopathologie.univ-rennes1.fr 43 HITEX SAS MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services As your industrial partner, HITEX SAS puts its human and supercritical CO2 resources at your disposal. Our expertise in all supercritical CO2 processes (extraction, fractionation, separation, purification, impregnation and formulation), allows us to accompany your project from beginning to end: • In R&D: to develop new products and processes • At scale-up: to produce at the lowest cost using supercritical CO2 • Providing technical support: improvement of processes including purification Our client sectors include perfumes/aromas, cosmetics, biomedical and pharmaceuticals, nutraceuticals and phytotherapy, and chemistry. TYPE OF STRUCTURE ENTERPRISE Keywords extraction, fractionation, purification, supercritical CO2, molecular distillation TECHNOLOGICAL CENTER TECHNICAL CORE FACILITY Contact Irène LAMOUR ESTABLISHED IN 1997 BUSINESS SECTOR Rue Louis Lefèvre Utile Z.I. Pentaparc BP 33601 56306 VANNES FRANCE Tel. +33(0)2 97 68 88 88 Fax: +33(0)2 97 68 88 80 [email protected] www.hitex-co2.com 44 ICIBIO MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION Description of services IciBio provides medical and scientific writing, literature searches and analyses, documentation, biological sequence searches, bibliographic database implementation, patent priority searches and English / French translation. REGULATORY & REGISTRATION MARKETING Keywords scientific information, bibliography, documentation, translation, writing, medical Contact TYPE OF STRUCTURE Françoise BONNICI ENTERPRISE TECHNOLOGICAL CENTER TECHNICAL CORE FACILITY 4 chemin de Bellevue 22520 BINIC FRANCE Tel. +33(0)2 96 73 33 03 Fax: +33(0)2 96 73 33 03 [email protected] www.icibio.com ESTABLISHED IN 1997 BUSINESS SECTOR 45 ID.MER MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services ID.Mer contributes to the development and promotion of the sea product industry: • Coordination of cooperation between scientific and technical research and the sea product industry • Trials for optimizing sea product processing techniques: design, innovation, development • Information dissemination, technology watching, knowledge transfer, consultancy • Organization of events for the sea product industry • Exploitation of marine co-products in the human and animal health and nutrition sectors TYPE OF STRUCTURE Keywords ENTERPRISE development, manufacturing, expert analysis, sea products, co-products, exploitation, biotechnology TECHNOLOGICAL CENTER TECHNICAL CORE FACILITY Contact Patrick ALLAUME ESTABLISHED IN 1987 BUSINESS SECTOR 2 rue Batelière 56100 LORIENT FRANCE Tel. +33(0)2 97 83 86 83 Fax: +33(0)2 97 37 11 03 [email protected] www.idmer.com 46 IDHESA BRETAGNE OCEANE MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services IDHESA Bretagne Océane provides consultancy and expert analysis in the fields of water quality, environment and food hygiene. The laboratory is COFRAC 1-1827 and 1-1828 accredited and is certified by the French Ministries of Health, and of Environment and Agriculture for: • Analysis of drinking water, river/coastal/marine water, effluent water, sludge, leachates, soil and sediments • Physical chemistry analyses, micropollutants, microbiological testing for drinking water, river/coastal/marine water, effluent water, food products, biological matrices, sludge, leachates, composts, soil and sediments • Animal health IDHESA also pursues internal R&D in various fields of activity. TYPE OF STRUCTURE Keywords ENTERPRISE consultancy, expert appraisal, analysis, R&D, water, environment, food, animal health TECHNOLOGICAL CENTER TECHNICAL CORE FACILITY Contact ESTABLISHED IN 2007 BUSINESS SECTOR Eric LAPORTE, Gaël DURAND Technopôle Brest-Iroise 120 avenue Alexis de Rochon BP 52 29280 PLOUZANE FRANCE Tel. +33(0)2 98 34 11 00 Fax: +33(0)2 98 34 11 01 [email protected] www.idhesa.fr 47 IMPACCELL MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY Description of services CHARACTERIZATION VALIDATION The Imaging-cell biochips core facility ImPACcell offers its skills, expertise and analytical resources in large-scale biological screening assays: FORMULATION • Toxicity and activity assays for chemicals, environmental pollutants and toxins, etc. REGULATORY & REGISTRATION • Specific liver toxicity assays MARKETING • Optimization of cell models for liver toxicity research • Cell-based functional assays using fluorescent labels • Determination of tissue-specific characteristics • Multiplexed gene expression analysis • Advice on cell culture and models • High-throughput in situ imaging of organized cell systems. TYPE OF STRUCTURE ENTERPRISE TECHNOLOGICAL CENTER Keywords toxicology, pharmacology, healthcare, cancer, nutrition Contact TECHNICAL CORE FACILITY Christiane GUILLOUZO ESTABLISHED IN 2005 BUSINESS SECTOR Faculté de Médecine Bâtiment 8 2 avenue du Pr Léon Bernard 35043 RENNES FRANCE Tel. +33(0)2 99 54 74 00 Fax: +33(0)2 99 54 01 37 [email protected] imagerie-puces-a-cellules.univ-rennes1.fr 48 INNOVA PROTEOMICS MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services The proteomics service company Innova Proteomics provides R&D and analytical solutions for protein and peptide products. Innova Proteomics offers a wide range of services with various degrees of sophistication, from protein characterization through to full-service, large-scale proteomics programs: protein identification, quality control of biomanufactured proteins, biomarker development, toxicoproteomics, exploitation of bioproducts and ingredients, and the identification of bioactive proteins and peptides. Innova Proteomics has developed a process for the discovery and identification of natural, bio-active peptides. The process screens bioresources for novel therapeutic peptides or new ingredients. TYPE OF STRUCTURE ENTERPRISE Keywords proteomics, peptide, proteins, biomarkers, identification, drug discovery, quality control TECHNOLOGICAL CENTER TECHNICAL CORE FACILITY Contact Nathalie MELAINE ESTABLISHED IN 2003 BUSINESS SECTOR Campus de Beaulieu Bât. 24 CS 2407 263 avenue du Général Leclerc 35042 RENNES CEDEX FRANCE Tel. +33(0)2 23 23 52 80 Fax: +33(0)2 23 23 52 82 [email protected] www.innova-proteomics.com 49 INPI MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION Description of services The French National Patent and Trademark Office (INPI) provides the following services: FORMULATION • Information on intellectual property, awareness-raising activities REGULATORY & REGISTRATION • Intellectual property strategy reviews MARKETING • Patent and literature searches • Receipt of patent, trademark and registered design applications • Training • Innovation support Keywords TYPE OF STRUCTURE ENTERPRISE patent, know-how, trademark, intellectual property, contract, protection Contact TECHNOLOGICAL CENTER TECHNICAL CORE FACILITY ESTABLISHED IN 1983 Vincent CARRE 15 rue du chêne Germain 35510 CESSON SEVIGNE FRANCE Tel. +33(0)8 20 21 32 13 Fax: +33(0)2 99 36 99 29 [email protected] www.inpi.fr BUSINESS SECTOR 50 INRA ANIMAL FIELD STATION MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION Description of services This field station has a wide range of tools for use in research into pig physiology, pig production systems and human nutritional health (in which the pig is used as animal model): VALIDATION • A conventional 200-sow herd FORMULATION • Ongoing constitution of a herd of minipigs REGULATORY & REGISTRATION MARKETING • Access to other animal species: poultry, calves, rabbits, etc. • Trial housing: farrowing houses, housing for weaned piglets, growing pigs in individual or group sties, young breeding sows, climatecontrolled housing • Special buildings and tools, such as operating rooms, an imaging core facility, respiratory chambers, rooms for behavioural testing, monitoring or nutritional status investigations • A mill and a slaughterhouse • Specialist operatives TYPE OF STRUCTURE It also supplies experimental animals to third parties and provides a number of services, such as the production of test batches of animal feed and data collection on carcasses post-slaughter or under controlled conditions. ENTERPRISE TECHNOLOGICAL CENTER Keywords TECHNICAL CORE FACILITY pig production systems, pigs, minipigs, animal feed and nutrition, human food and nutrition, healthcare ESTABLISHED IN 1980 Contact Jean NOBLET BUSINESS SECTOR UMR SENAH Domaine de la Prise 35590 SAINT-GILLES FRANCE Tel. +33(0)2 23 48 52 00 Fax: +33(0)2 23 48 50 80 [email protected] www.rennes.inra.fr/senah/install.html 51 IPL SANTE, ENVIRONNEMENT DURABLES BRETAGNE MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services IPL offers analytical services for a variety of environmental matrices (water, sludges, sediments, air, etc.). IPL is a specialist in biodegradability studies of plastics and the characterization of antifouling paints. Certified by the French Ministry of Health and Ministry of the Environment, the laboratory is also GLP-compliant for residue studies and COFRAC accredited (ISO 17025). Keywords physical chemistry, biodegradability, microbiological analyses, water, pesticides TYPE OF STRUCTURE ENTERPRISE Contact TECHNOLOGICAL CENTER Elisabeth LE FUR TECHNICAL CORE FACILITY Parc Technologique de Soye 4 rue de Galilée 56270 PLOEMEUR FRANCE Tel. +33(0)2 97 80 80 80 Fax: +33(0)2 97 80 80 86 [email protected] www.ipl-groupe.fr ESTABLISHED IN 1984 BUSINESS SECTOR 52 IRMA MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services The IRMA performs contract/collaborative development of innovative technologies in environmental and energy sectors: • Development of catalytic or adsorption-based technologies for reducing atmospheric pollutant emissions (NOX, N2O, COV, NH3, CO, etc.). Production of catalysts • Waste processing and exploitation: treatment of pig slurry, plastic recycling, thermolysis of organic waste (four pilot trials with analysis of the material/energy balance), prototype engineering and production • Production of hydrogen from fossil or renewable hydrocarbon sources (linked to fuel cell development) The IRMA also provides the following services: • Physical-chemical analyses (SEM, EDX, XRD, etc.) and on-site gas emission analyses • Synthesis and processing of mineral products TYPE OF STRUCTURE • Expert analysis: audits, project engineering and consultancy ENTERPRISE • Elaboration of solvent management plans – emissions control procedures – regulatory intelligence – feasibility studies – technical, economic and environmental analyses of equipment and installations TECHNOLOGICAL CENTER • Carbon balance analysis (ADEME-accredited) and greenhouse gas accounting TECHNICAL CORE FACILITY ESTABLISHED IN 1990 Contact Christian HAMON BUSINESS SECTOR 9 rue Galilée Parc Technologique de Soye BP 64 56274 PLOEMEUR CEDEX FRANCE Tel. +33(0)2 97 83 55 55 Fax: +33(0)2 97 83 38 83 [email protected] www.irmatech.com 53 KORILOG MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services Korilog is a bioinformatics company providing academic and industry research laboratories with next generation software solutions in the key areas of biological data integration, exploration, management and visualization. Korilog provides ready-to-use graphical software (koriblast.com, koriviewer.com) enabling comprehensive exploration of sequence databanks and associated data, from raw nucleotide and protein sequences up to functions, 3D structures and pathways. The company provides expert software development services to integrate specialized modules in Korilog's software, or create tailored tools and databanks to support researchers in their R&D activities. TYPE OF STRUCTURE Keywords genomics, proteomics, drug discovery, bioinformatics ENTERPRISE TECHNOLOGICAL CENTER TECHNICAL CORE FACILITY Contact Patrick DURAND ESTABLISHED IN 2004 BUSINESS SECTOR BP 34 56190 MUZILLAC FRANCE Tel. +33(0)9 60 36 80 38 Fax: +33(0)2 97 42 88 20 [email protected] www.korilog.com 54 LABOFARM MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services Labopharm is a veterinary laboratory which specializes in biomolecular diagnostics (genetic testing and PCR assays). With 20 years of experience in the field of veterinary diagnostics, the Labopharm laboratory is at the cutting edge of disease screening technologies. For example, the molecular biology unit can screen for over thirty bacterial and viral animal pathogens. The unit's operating procedures comply with the rigorous standards required for the French COFRAC accreditation (ISO 17025). Labopharm is highly involved in selection and breeding in the poultry-, pigand fish-farming sectors. Labopharm is now pursuing its development by aligning its analytical methods with the technologies generated in research labs and by developing new tests that meet the needs of farmers and veterinarians. TYPE OF STRUCTURE Keywords ENTERPRISE TECHNOLOGICAL CENTER genetic screening for pathogens, DNA bird sexing, genetic testing, PCR, veterinary health TECHNICAL CORE FACILITY Contact ESTABLISHED IN 1990 Jean LE GUENNEC BUSINESS SECTOR 4 rue Théodore Botrel BP 351 22603 LOUDEAC FRANCE Tel. +33(0)2 96 28 63 43 Fax: +33(0)2 96 66 08 88 [email protected] www.labofarm.com 55 LABORATOIRES ADITEC MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services Laboratoires Aditec is an expert in dry powder technologies and formulations, such as effervescent products and micro-encapsulated ingredients. Our products are supplied to leading food supplement and feed additive retailers. Laboratories Aditec is a top choice for high-quality, full-service, sub-contracted manufacturing of nutraceutical products. Keywords effervescent products, granulation, manufacturing, encapsulation TYPE OF STRUCTURE Contact ENTERPRISE Alexandre RAGUET TECHNOLOGICAL CENTER 55 boulevard Jules Verge BP 10180 35803 DINARD CEDEX FRANCE Tel. +33(0)2 99 16 52 05 Fax: +33(0)2 99 16 52 14 [email protected] www.laboratoiresaditec.com TECHNICAL CORE FACILITY ESTABLISHED IN 1996 BUSINESS SECTOR 56 service provision, custom LABORATOIRES D'ARMOR MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services Laboratoires d'Armor has been providing its services and products to French and international customers for over 20 years. The company specializes in the custom formulation, manufacturing and packaging of cosmetic products. Laboratoires d'Amor's skilled, experienced cosmetologists can produce your formulas and advise you on the latest textures and active substances. Our technology-watching capability enables us to identify and help you leverage the latest innovations. Keywords marine cosmetics, professional, natural TYPE OF STRUCTURE ENTERPRISE Contact TECHNOLOGICAL CENTER Sandrine MORVAN TECHNICAL CORE FACILITY Presqu'ile de Pen Lan 22610 PLEUBIAN FRANCE Tel. +33(0)2 96 16 59 30 Fax: +33(0)2 96 16 59 34 [email protected] www.labo-armor.fr ESTABLISHED IN 1987 BUSINESS SECTOR 57 LAREAL MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION Description of services Lareal performs physical-chemical analyses of raw materials and finished products in the feed, food and pet food sectors. FORMULATION REGULATORY & REGISTRATION MARKETING Keywords laboratory, physical-chemical analyses, nutritional value, GMO, heavy metals, microtoxins, amino acids Contact Claude CHARRETEUR TYPE OF STRUCTURE ENTERPRISE TECHNOLOGICAL CENTRE TECHNICAL CORE FACILITY BP 234 56006 VANNES CEDEX FRANCE Tel. +33(0)2 99 55 14 14 Fax: +33(0)2 99 55 14 15 [email protected] www.lareal.com ESTABLISHED IN 1954 BUSINESS SECTOR 58 LEHA MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services The LEHA laboratory provides analytical and consultancy services. It has over 25 years' experience of assisting manufacturers, retailers, small business and local authorities with their quality control and product/service development. Our services include physical chemistry analyses, nutritional analyses, bacteriological analyses, sensory testing, bovine spongiform encephalopathy screening. Our fields of expertise include: • Food products • Pet food • Cosmetics • Hygiene products TYPE OF STRUCTURE Keywords ENTERPRISE TECHNOLOGICAL CENTER testing, quality control, consultancy, training, audit, food, hygiene, beauty products TECHNICAL CORE FACILITY Contact ESTABLISHED IN 1984 Katicha MENGUY BUSINESS SECTOR Les Tertres Noirs BP 40526 35500 VITRE CEDEX FRANCE Tel. +33(0)2 99 74 10 54 Fax: +33(0)2 99 74 10 55 [email protected] www.leha.fr 59 LRBEVA NUTRITION MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services Incorporated in 1987 as NUTRINOV, the company has since been renamed as LRBEVA NUTRITION. Our core skill is the development of innovative food products for manufacturers and retailers. Creating a new food product or introducing a new ingredient while maintaining the product's organoleptic and functional qualities requires a rigorous approach that can be likened to pharmaceutical product development. LRBEVA NUTRITION's experienced staff provides comprehensive project support - from the idea through to market launch: • Prototype development • Scientific analysis, health claims and the implementation of trials • Product development and industrial scale-up TYPE OF STRUCTURE ENTERPRISE LRBEVA NUTRITION handles these and other steps for its industrial customers. Keywords TECHNOLOGICAL CENTER TECHNICAL CORE FACILITY formulation, design, development, evaluation, regulatory support, food products ESTABLISHED IN 2004 Contact Loïc ROGER BUSINESS SECTOR Rue Siméon Poisson Campus de Ker Lann 35170 BRUZ FRANCE Tel. +33(0)2 99 52 54 00 Fax: +33(0)2 99 52 54 01 [email protected] www.lrbeva.com 60 MAZAL PHARMACEUTIQUE MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services Mazal Pharmaceutique has specialized in dry formulations for the last 30 years. It provides services in the pharmaceutical and nutraceutical sectors. Its staff's expertise in formulation, analytical development and industrial production enable the company to design, develop and custommanufacture all types of active compounds and finished products to guaranteed GMP standards. Mazal Pharmaceutique offers the following services: • Pharmaceutical formulation and forming • Physicochemical analysis/ICH stability testing • Custom manufacturing (in capsule, sachet or tablet formats) • Production of clinical batches • Scientific support for regulatory documents (new drug applications, EFSA filings, etc.) TYPE OF STRUCTURE Mazal Pharmaceutique is an accredited service provider under France's research tax credit scheme. ENTERPRISE TECHNOLOGICAL CENTER TECHNICAL CORE FACILITY ESTABLISHED IN Contact Bernard LE DOUAIRON BUSINESS SECTOR 11 rue Rontgen 29337 QUIMPER CEDEX FRANCE Tel. +33(0)2 98 53 54 55 Fax: +33(0)2 98 53 54 55 [email protected] 61 MICROMER MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION Description of services Micromer has been doing business in the industrial and environmental microbiology sectors for over 20 years and has more than 10 years of experience in the microbiology of cosmetic products. REGULATORY & REGISTRATION Micromer is the microbiology division of the IDEA group and is GLP-certified for genotoxicity testing. MARKETING Its main areas of expertise in the cosmetics sector are as follows: • Challenge tests • Quality control of finished products and raw materials • Screening for and identification of potentially pathogenic microorganisms • Bactericidal and fungical activities • Genotoxicity testing (the Ames test) Micromer also specializes in marine microbiology. TYPE OF STRUCTURE ENTERPRISE Keywords TECHNOLOGICAL CENTER micro-organisms, cosmetic products, marine environment TECHNICAL CORE FACILITY ESTABLISHED IN 1990 Contact Sophie CORRE BUSINESS SECTOR Technopôle Brest Iroise 90 rue René Descartes 29280 PLOUZANE FRANCE Tel. +33(0)2 98 05 19 70 Fax: +33(0)2 98 05 09 73 [email protected] www.ideatest.fr 62 MRIC MICROSCOPY RENNES IMAGING CENTER MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY Description of services CHARACTERIZATION VALIDATION The Microscopy Rennes imaging center (MRic) comprises 4 facilities: • MRic-ALMF: advanced light microscopy FORMULATION • MRic-NANO: NanoSIMS spectrometry) REGULATORY & REGISTRATION • MRic-MPM: multiphoton microscopy MARKETING • MRic-TEM: transmission electron microscopy (high-resolution secondary ion mass MRic offers access to imaging systems, scientific and technical support in experimental and project design and training in microscopy techniques. We have special expertise in: • Rapid, real-time in vitro cell imaging • Structural analysis • Molecular and atomic imaging • Protein-protein interactions (FRET and FLIM) TYPE OF STRUCTURE • In vitro enzyme assays • Correlation fluo-TEM and Fluo-NanoSIMS ENTERPRISE TECHNOLOGICAL CENTER Keywords TECHNICAL CORE FACILITY confocal, multiphoton microscopy, electron microscopy, cryomicroscopy, tomography, nanoSIMS, videomicroscopy ESTABLISHED IN 2008 Contact Claude PRIGENT BUSINESS SECTOR Faculté de Médecine 2 avenue du Pr Léon Bernard 35043 RENNES FRANCE Tel. +33(0)2 23 23 47 31 Fax: +33(0)2 23 23 44 78 [email protected] microscopie.univ-rennes1.fr 63 NUTRAVERIS MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services Nutraveris is Europe's leasing scientific and regulatory consultancy in the nutrional health market. We support and advise laboratories, pharmaceutical firms, agrifood groups and cosmetics companies on full market approval and the optimization of product leadership in compliance with legislative requirements. Thanks to a solid team of scientists and experts in regulatory affairs and our unique, real-time database, Nutraveris facilitates the formulation and validation of a product's efficacy by developing scientific arguments and setting up clinical trials. We build and file applications with international regulatory bodies, including applications to the community register of approved nutrition and health claims under EU Regulation 1924/2006. TYPE OF STRUCTURE Keywords ENTERPRISE formulation, nutrition, health, food supplements, diet foods, healthful ingredients, claim registration, notification, regulatory audits, database TECHNOLOGICAL CENTER TECHNICAL CORE FACILITY Contact ESTABLISHED IN 2006 BUSINESS SECTOR Cédric BOURGES 18 C rue du Sabot 22440 PLOUFRAGAN FRANCE Tel. +33(0)2 96 76 54 87 Fax: +33(0)2 96 76 63 26 [email protected] www.nutraveris.com 64 ONIS MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services ONIS (Observatoire national d'imagerie scientifique) is a high-performance, multi-scale analytical imaging core facility. Its equipment can visualise the chemical composition point by point in a tissue, a polymer, a soil sample, an insect, a plant or a lichen, etc., from the millimeter scale to the nanometer scale. The facility offers imaging and elemental analysis services, personalized customer support services and protocol design, testing and image analysis and processing. ONIS also offers face-to-face training or e-training. Keywords TYPE OF STRUCTURE analytical imaging, spectroscopy, spectrometry, NanoSIMS and RAMAN, fluorescence imaging, 2D/3D imaging, TEM, micrometer and nanometer techniques ENTERPRISE TECHNOLOGICAL CENTER Contact TECHNICAL CORE FACILITY Olivier LAVASTRE ESTABLISHED IN 2005 BUSINESS SECTOR UMR CNRS 6226 Campus de Beaulieu 263 avenue du Général Leclerc CS 74205 35042 RENNES CEDEX FRANCE Tel. +33(0)2 23 23 56 30 [email protected] 65 PIXEL MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services PIXEL (Plate-forme d'imagerie multi(X)photonique étendue large bande) is a fluorescence and harmonic photon microscopy facility which provides the scientific community with modern, high-performance tools for the fivedimensional functional, spatial and time-domain investigation (x, y, z, λ and t) of biological material. The core facility has two scanning light microscopes fitted with pulsed laser sources. This notably enables the analysis of biological samples to a depth of up to 1 mm, at the limits of multiphoton microscopy. In harmonic modes, multiphoton microscopy enables the in situ imaging of a number of hyperpolarizable molecules (collagen, myosin, tubulin, starch, cellulose, etc.). Keywords TYPE OF STRUCTURE multiphoton imaging, confocal and harmonic microscopy ENTERPRISE TECHNOLOGICAL CENTER Contact TECHNICAL CORE FACILITY François TIAHO ESTABLISHED IN 2005 BUSINESS SECTOR Campus de Beaulieu Bât.13, pièce 246 263 avenue du Général Leclerc 35042 RENNES CEDEX FRANCE Tel. +33(0)2 23 23 57 18 [email protected] pixel.univ-rennes1.fr 66 POLARIS MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services Polaris is a specialist provider of nutritional and functional lipids. The company offers a full range of omega-3-rich fish oils and omega-6-rich plant oils. The company's specific expertise in lipid chemistry and the stabilization of these polyunsaturated fatty acid-rich oils means that it can supply these products in several pharmaceutical formulations: liquids, powders (microcapsules), gels, emulsions and capsules. For powder formulations, Polaris can microencapsulate plant-, animal- or mineral-derived raw materials. Its technological innovations enable a high active compound concentration, maximum protection, taste and odor masking and controlled release. Polaris also performs new product development and subcontracting. TYPE OF STRUCTURE formulation, trials, technical Applications: formulation and stabilization of new molecules, new product development and trials in the field of polyunsaturated fatty acids, development for pharmaceuticals, nutraceuticals, health food, baby food, food supplements, agrifood, cosmetics, animal health and animal feed. ENTERPRISE TECHNOLOGICAL CENTER Keywords TECHNICAL CORE FACILITY lipid chemistry, microencapsulation, stabilization, protection, antioxidants, natural oils, formulation, evaluation ESTABLISHED IN 1994 Contact Stéphane LOZACHMEUR BUSINESS SECTOR Chemin de Quilourin Moulin du Pont 29170 PLEUVEN FRANCE Tel. +33(0)2 98 54 84 20 Fax: +33(0)2 98 54 84 51 [email protected] www.polaris.fr 67 POLYMARIS BIOTECHNOLOGY MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION Description of services VALIDATION Polymaris Biotechnology is a specialist in the discovery, characterization and exploitation of novel marine biomolecules. FORMULATION REGULATORY & REGISTRATION MARKETING Our focus is on exopolysaccharides produced by bacteria from the company's private collection of marine micro-organisms (which currently contains over 500 isolates). From these Polymaris is currently developing more than ten entirely new, pure, fully-characterized molecules. It also offers custom hemi-synthesis using these molecules. The target markets for the industrial application of these biodegradable, natural compounds are nutraceuticals, fine chemicals, the environment, agrifood, cosmetics, dermocosmetics and, in the longer term, healthcare. Keywords TYPE OF STRUCTURE marine biomolecules, bacteria, exopolysaccharides ENTERPRISE TECHNOLOGICAL CENTER Contact TECHNICAL CORE FACILITY Anthony COURTOIS ESTABLISHED IN 2008 BUSINESS SECTOR Pépinière d’entreprises du pays de Morlaix Aéropôle Centre 29600 MORLAIX FRANCE Tel. +33(0)2 98 88 04 57 Fax: +33(0)2 98 88 38 94 [email protected] www.polymaris.com 68 PRISM MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services The functional imaging core facility PRISM (Plate-forme rennaise d'imagerie et de spectroscopie structurale et métabolique) offers a range of outstanding, well-matched methodological skills (imaging, spectroscopy, MRI, NMR and CT) for the investigation of experimental models on the molecular scale (proteins and lipids), the cell level (bacteria, membranes, etc.), the tissue level (muscle and tumours), in the small animal (mice, rats, fishes and rabbits) and in larger animals (chickens, sheep and pigs). PRISM has particular expertise in the following areas: • The biomedical sector: morphological and functional typing of transgenic animals, dynamic studies of drug activity, the digestive impact of food product formulations and neurofunctional satiety studies • Biology and agronomy: quantification of tissue distribution in animal and plant systems, membrane system studies, etc. • Food science: ingredient and food product processability, water retention properties and storage stability testing TYPE OF STRUCTURE • Process engineering: mass and heat transfer analysis for bioproducts ENTERPRISE TECHNOLOGICAL CENTER TECHNICAL CORE FACILITY Keywords imaging, spectroscopy, MRI, NMR, tomography, scanner ESTABLISHED IN 2003 Contact François MARIETTE BUSINESS SECTOR Cemagref 17 avenue de Cucillé CS 64427 35044 RENNES CEDEX FRANCE Tel. +33(0)2 23 48 21 78 Fax: +33(0)2 23 48 21 15 [email protected] prism.univ-rennes1.fr 69 PROCLAIM MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services Proclaim is a contract research organization (CRO) which specializes in efficacy tests for cosmetics and nutritional products: • Innovative tests, custom-designed trials and standard assays are used to evaluate ingredients and/or end products. • In vitro assay methods (cultured fibroblasts, keratinocytes and adipocytes or human skin cultures, etc.) • Performance of clinical studies in compliance with GLP and the legislation on biomedical research Trials on healthy volunteers for marketing, scientific or regulatory purposes are performed in compliance with current quality and ethical standards. Keywords TYPE OF STRUCTURE cosmetic products, food supplements, in vitro testing, trials on healthy volunteers, clinical trials ENTERPRISE TECHNOLOGICAL CENTER TECHNICAL CORE FACILITY Contact Dominique DE JAVEL, Sonia GUILLOU ESTABLISHED IN 1999 BUSINESS SECTOR Parc d’Affaires de la Bretèche Bât. B1 35760 SAINT-GREGOIRE FRANCE Tel. +33(0)2 23 25 02 02 Fax: +33(0)2 23 25 29 74 [email protected] www.proclaim.fr 70 PRODIABIO MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services The Prodiabio facility focuses on waste and effluent treatment and the exploitation of industrial co-products (methanization, biodigestion, etc.). Cooking trials and food product formulation can be performed in the agrifood process suite and the associated sensorial analysis unit. Prodiabio's skills in liquid and solid biofuels (boilers, stoves, etc.), mechanical engineering, automation and maintenance enable it to meet the needs of industrial businesses, local authorities and farm managers. Keywords process, environmental diagnosis, bioresources TYPE OF STRUCTURE Contact ENTERPRISE TECHNOLOGICAL CENTER TECHNICAL CORE FACILITY ESTABLISHED IN 2005 Olivier SIRE Allée des Pommiers 56300 PONTIVY FRANCE Tel. +33(0)2 97 27 67 70 Fax: +33(0)2 97 27 81 53 [email protected] www.pft-prodiabio.com BUSINESS SECTOR 71 SAFECOS ASSOCIATES MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION Description of services Safecos associates provides expertise in toxicology and consultancy on safety testing. Our services include: FORMULATION • Toxicological profiling REGULATORY & REGISTRATION • Health testing of cosmetic products in compliance with European Union regulation 1223/2009 MARKETING • Specific expertise in cosmetic products for children under the age of 3 • File audits for cosmetic products • Evaluation of CAM processes • Regulatory affairs support and consultancy Keywords TYPE OF STRUCTURE consultancy, cosmetics, toxicological profiling, regulatory compliance, safety testing ENTERPRISE TECHNOLOGICAL CENTER TECHNICAL CORE FACILITY Contact Dominique de JAVEL ESTABLISHED IN 1999 BUSINESS SECTOR Parc d’Affaires de la Bretèche Bâtiment B1 35760 SAINT-GREGOIRE FRANCE Tel. +33(0)2 99 23 68 30 Fax: +33(0)2 23 25 29 74 [email protected] www.safecos.com 72 SCIENCE ET MER MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION Description of services For over 20 years, Science et Mer has been exploiting the particularly abundant seaweed resources on Brittany's northern coast. The company is now a leader in the development of products containing marine-based ingredients and has deployed its expertise in two main areas: REGULATORY & REGISTRATION • The custom manufacturing of health and beauty products MARKETING • Supplying thalassotherapy centers, spas and clinics with frequently used products, such as seaweed powders, marine mud and poultices The company produces a number of marine-based ingredients in-house using biotechnological processes. Science et Mer's mission is to provide its customers with high-quality services in several areas of expertise: • Cosmetic formulation: creating new formulations and testing their stability, skin tolerance and efficacy and handling regulatory requirements • Bulk manufacture TYPE OF STRUCTURE ENTERPRISE • Packaging: choice of packaging and appropriate graphic design for well-defined overall concepts • Finished product assembly and packaging TECHNOLOGICAL CENTER TECHNICAL CORE FACILITY Keywords marine-based ingredients, manufacturing ESTABLISHED IN 1986 Contact Didier LE TANNOUR BUSINESS SECTOR BP 50 Venelle du Carros 29480 LE RELECQ KERHUON FRANCE Tel. +33(0)2 98 28 34 29 Fax: +33(0)2 98 28 40 32 [email protected] www.scienceetmer.com 73 SEADEV FERMENSYS MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services Seadev-Fermensys is the exclusive provider of extremophile marine bacteria collections, including Ifremer’s marine hydrothermophilic strains commercialized under an exclusive trade license. Our two development sites (each with integrated research core facilities) offer a comprehensive range of services for the screening, development and industrialization of novel natural compounds and innovative bioprocesses. Seadev-Fermensys offers the sub-contracting of fermentation processes, bioconversions, process optimization, bioremediation and biopolymer screening. The company can also meet your demand in biomass production (fungi, bacteria, yeasts, non-GMOs), industrial feasibility and scale-up studies. TYPE OF STRUCTURE ENTERPRISE TECHNOLOGICAL CENTER Keywords strain library, biopolymers, fermentation, biotechnology, bioremediation, screening, exopolysaccharides, bioplastics TECHNICAL CORE FACILITY Contact ESTABLISHED IN 2004 BUSINESS SECTOR Pierre-Jacques DAUNEAU 185 rue René Descartes Technopôle Brest Iroise 29280 PLOUZANE FRANCE Tel. +33(0)2 98 49 85 97 Fax: +33(0)2 98 49 85 96 [email protected] www.seadev-fermensys.com 74 bioconversion, marine industrial production, SEQUENCING/ GENOTYPING CORE FACILITY MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services This core facility offers R&D services in sequencing and genotyping, from mid- to high-throughput, including: • EST analysis • Pyrosequencing and de novo sequencing • Diversity • Environmental and functional genomics • Polymorphism analysis • Physical and genetic chromosome mapping • Positional cloning • Identification of genetic determinants • Diagnostic tools • Genetics of biodiversity TYPE OF STRUCTURE ENTERPRISE Keywords TECHNOLOGICAL CENTER sequencing, genotyping, DNA extraction, DNA purification TECHNICAL CORE FACILITY Contact ESTABLISHED IN 2002 Philippe VANDENKOORNHUYSE BUSINESS SECTOR CNRS UMR 6553 EcoBio OSU de Rennes 263 Avenue du General Leclerc CS 74205 35042 RENNES CEDEX FRANCE Tel. +33(0)2 23.23.50.07 [email protected] www.sb-roscoff.fr/SG 75 STEPP BRETAGNE MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION Description of services STEPP (Station technique d’expérimentation des plantes en pot) is a notfor-profit organization which specializes in pot plant and bedding plant trials. REGULATORY & REGISTRATION In response to requests from its members, STEPP Bretagne sets up and monitors trials at its field station. MARKETING The field station's three main activities are: • The improvement of crop management techniques and the optimization of pot plant and bedding plant production • Expansion of the range of pot/bedding plants and diversification of their uses • The reduction of chemical inputs TYPE OF STRUCTURE ENTERPRISE Keywords horticulture, trials, applied research, development TECHNOLOGICAL CENTER TECHNICAL CORE FACILITY Contact Oscar STAPEL ESTABLISHED IN 1995 BUSINESS SECTOR Ecole d’horticulture de Saint-Ilan 52 rue de Saint-Ilan 22360 LANGUEUX FRANCE Tel. +33(0)2 96 52 47 13 Fax: +33(0)2 96 52 07 16 [email protected] www.astredhor.fr 76 SYNNANOVECT MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY Description of services CHARACTERIZATION VALIDATION FORMULATION The synthetic vector core facility SynNanoVect develops, optimizes and tests synthetic nanocarriers for the delivery of nucleic acids (DNA and siRNA) and biomolecules of interest. The core facility offers several products and services: REGULATORY & REGISTRATION • Design and development of synthetic nanocarriers MARKETING • Nanocarrier formulation • Physical-chemical characterization • Delivery efficiency measurements • Pre-clinical safety testing • Transgene constructs TYPE OF STRUCTURE ENTERPRISE The facility's chemistry lab specializes in vector synthesis and characterization. The biology lab offers a wide range of in vitro and in vivo models and various items of equipment for the in vivo assessment of nanocarrier efficacy, toxicity and inflammation parameters. Keywords TECHNOLOGICAL CENTER TECHNICAL CORE FACILITY biotherapy, gene and drug delivery, synthetic vectors, in vivo imaging assays, formulation, characterization ESTABLISHED IN 2003 Contact Tristan MONTIER BUSINESS SECTOR Unité Inserm 613 Bâtiment 2bis Hôpital Morvan 5 avenue du Maréchal Foch 29200 BREST FRANCE Tel. +33(0)2 98 01 80 80 Fax: +33(0)2 98 01 83 42 [email protected] http://ouest-genopole.org/index.php?pa=N342&Ia=fr 77 VEGENOV MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services Vegenov provides its customers with the benefit of over 20 years of experience in plant biotechnology, disease diagnosis and sensorial and nutritional analysis. It offers the following services: • Creation of new plant varieties: haplomethods, embryo rescue, markeraided selection, genetic distance estimation, resistance tests, etc. • Crop protection: evaluation of phytosanitary products, disinfectants and natural defence elicitors, alternative crop protection approaches, pathogen detection • Identification and traceability: genotyping (genetic fingerprinting) for checking genetic purity, detecting fraud and resolving legal disputes, etc. • Improvement of seedlings and stock plants • Product quality: exploitation of nutritional assets and sensorial qualities TYPE OF STRUCTURE • Project support: expert market and technology analysis, project set-up and coordination, training. ENTERPRISE TECHNOLOGICAL CENTER TECHNICAL CORE FACILITY Keywords biotechnology, plant diseases, creation of new varieties, quality, sensorial evaluation, expert analysis, training, consultancy ESTABLISHED IN 1989 Contact Serge MABEAU BUSINESS SECTOR Penn Ar Prat 29250 SAINT POL DE LEON FRANCE Tel. +33(0)2 98 29 06 44 Fax: +33(0)2 98 69 24 26 [email protected] www.vegenov.com 78 VOISIN CONSULTING LIFE SCIENCES MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services Voisin Consulting Life Sciences advises biomedical, biotech and pharmaceutical companies (including start-ups) on the design and implementation of their global regulatory strategy. Emphasis is placed on Europe/USA harmonization. Voisin Consulting offers services ranging from the definition and implementation of a regulatory strategy for the initial stages of product development through to the clinical phases and then the preparation, assembly and submission of market authorization/CE mark applications. Keywords consulting, regulatory strategy TYPE OF STRUCTURE Contact ENTERPRISE TECHNOLOGICAL CENTER TECHNICAL CORE FACILITY ESTABLISHED IN 1997 Anne DUPRAZ-POISEAU Espace Performance Bâtiment J 35769 SAINT-GREGOIRE FRANCE Tel. +33(0)2 23 25 07 68 Fax: +33(0)2 23 25 27 98 [email protected] www.voisinconsulting.com BUSINESS SECTOR 79 XENOBLIS MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION Description of services VALIDATION Xenoblis provides preclinical contract testing services for the evaluation of ADME, toxicity and pharmacokinetic properties of drug candidates. FORMULATION The company performs screening, mechanistic studies and GLP-compliant regulatory studies and its expertise extends into in vitro models. REGULATORY & REGISTRATION MARKETING Xenoblis has developed a set of services for drug interaction modelling (inhibition and induction), drug clearance, metabolic stability, metabolic profiling, inter-species comparison and influx/efflux transporter assays. It has also developed (i) drug permeability assays for the digestive tract, the skin and the blood-brain barrier and (ii) techniques for characterizing drugplasma protein interactions. Assay turnaround times are optimized by the use of liquid chromatographymass spectrometry (LC-MS/MS) and direct access to a biological resource collection comprising animal and human tissues and cells (hepatocytes, microsomes, plasma, skin, brain endothelial cells, etc.). TYPE OF STRUCTURE ENTERPRISE Keywords TECHNOLOGICAL CENTER pharmacokinetics, toxicology, in vitro assays, ADME, drug-drug toxicity, interactions study TECHNICAL CORE FACILITY ESTABLISHED IN 1987 Contact Françoise BREE BUSINESS SECTOR Parc d’Affaires de la Bretèche Bâtiment B1 35760 SAINT-GREGOIRE FRANCE Tel. +33(0)2 99 23 77 77 Fax: +33(0)2 23 25 29 74 [email protected] www.xenoblis.com 80 XENOPUS biological resource center MARKET RESEARCH BIOPRODUCTION SCREENING INTELLECTUAL PROPERTY CHARACTERIZATION VALIDATION FORMULATION REGULATORY & REGISTRATION MARKETING Description of services The ISO 9001-certified Xenopus biological resource center offers access to its expertise in Xenopus breeding, production and transgenesis: • Sale and supply of Xenopus frogs and Xenopus oocytes expressing proteins of interest • Use of the Xenopus model in research • Creation of transgenic Xenopus carrying a promoter linked to a fluorescent protein or another protein of interest • Testing of homologous or heterologous promoters • Gene-trap mutagenesis and the supply of mutants of interest • Training in Xenopus breeding and in vitro fertilization techniques TYPE OF STRUCTURE Keywords ENTERPRISE embryology, developmental ecotoxicology biology, TECHNOLOGICAL CENTER TECHNICAL CORE FACILITY Contact Thierry MADIGOU ESTABLISHED IN 2003 BUSINESS SECTOR Campus de Beaulieu Bât. 13 263 avenue du Général Leclerc 35042 RENNES CEDEX FRANCE Tel. +33(0)2 23 23 68 89 Fax: +33(0)2 23 23 50 52 [email protected] xenopus.univ-rennes1.fr 81 cell biology, pharmacology, Support Actors This catalog was made possible by CRITT Santé Bretagne and the support of many regional actors. CRITT Santé Bretagne wishes to particularly thank: • The members of the Bioservices steering committee: • CBB Développement, the tech transfer center for biotech and fine chemistry, provided valuable data and access to the structures involved in bioproduction. Pierrick AUVRAY - C.RIS Pharma Jean-Erik BLOCHET - Zoopôle Développement Arnaud DEVILLEZ - Bretagne Valorisation Véronique LEMONON - Pays de Morlaix Nathalie LETACONNOUX - CBB Développement Serge MABEAU & Christophe BAZINET - Vegenov Céline QUERON - Biogenouest For more information about the Capbiotek initiative For more information about molecular farming and bioproduction Capbiotek Contact: Jacques DE CERTAINES [email protected] www.capbiotek.fr CBB Développement Contact: Gilbert BLANCHARD [email protected] www.cbb-developpement.com