Denis Fourches

DENIS FOURCHES
9, rue des Hallebardes
67000 Strasbourg
FRANCE
Tel : (33)3-88-23-29-18
Cell : (33)6-18-87-46-63
Email : [email protected]
Birthday: January 5th 1980
Single
Nationality: French
Current position
2004-2007
PhD student - ChemoInformatics laboratory (Louis Pasteur University, Strasbourg).
Thesis director: Pr. Alexandre VARNEK
QSAR modeling of host-guest complexes. Enhancement of models accuracy using
clustering of diverse datasets and applicability domain of selected models.
Development of predictors involved in the ISIDA programs package.
Educational background
 Louis Pasteur University ULP, Strasbourg, France.
2003-2004 « DEA Chimie Informatique, mention Assez Bien ». Master (M2) degree in
ChemoInformatics.
 Louis Pasteur University ULP, Strasbourg, France.
2002-2003 « Maîtrise de Chimie, mention Assez Bien. » Master (M1) degree in Chemistry.
 University of Limoges, France.
2001-2002 « Licence de Chimie, mention Assez Bien. » Bachelor Degree in Chemistry.
 University of Limoges, France.
1998-2001 «DEUG biologie, deuxième année, mention Assez Bien. » Degree in Biology.
Professional background
2004-2007
Teacher at ACADOMIA (private company). 15 hours of private courses/week.
Teaching programs: mathematics, physics, chemistry, biology and biochemistry.
2003-2004
Master (M2) in ChemoInformatics - Training period: development of a clustering
module including hierarchical and non-hierarchical algorithms. Director: Pr. A.
VARNEK.
2002.2003
Master (M1) in Chemistry - Training period: QSAR modeling of uranyl extractants.
Director: A. VARNEK.
July 2002
Bachelor degree in Chemistry - Training period: synthesis of compounds using
the Jones reaction. Director: Pr. J. Ipaktschi (Giessen University, Germany).
1998-2001
Summers full time jobs: person in charge of the water quality of the Uzerche’s
swimming pool (France).
Computational skills
Environments: Unix/Dos/Windows 9X/2000/XP/Vista.
Programming languages: HTML, PHP, Javascript, Delphi, Pascal, C, CSH.
Software: Microsoft Office, ChemOffice (ChemFinder, ChemDraw, Chem3D…), ChemAxon, Isis
Base, Codessa Pro, ISIDA, Spartan, Quest, Vista, BioReason ClassPharmer, ACDLabs, Sybyl,
Delphi, C builder, Macromedia Dreamweaver, Flash …
Foreign languages
English:
fluent. (TOEIC Test: 885)
German:
technical level.
Hobbies
Movies, computer games, books, basket-ball, swimming pool, judo (brown belt).
Webmaster: http://infochim.u-strasbg.fr/
Driving licence.
Conferences and publications
A. Varnek, D. Fourches, N. Sieffert, V.P. Solov'ev, C. Hill and M. Lecomte;
QSPR modelling of the AmIII/EuIII separation factor: how far can we predict ?
J. Solv. Extr. Ion. Exch., 2007, 0000.
D. Fourches, V. Solov’ev, A. Varnek, O.Klimshuk, A. Ouadi and I. Billard. Computer-Aided
Design of New Metal Binders: Extraction of UO22+ by monoamides. 1rst European Chemistry
Congress, Budapest, 27-31 August 2006.
D. Fourches. “In silico” Design of New Metal Binders: Extraction of UO22+ by
Monoamides. French Chemistry Society Day, Illkirch, may 4, 2006.
Igor V. Tetko, Vitaly P. Solov’ev, Alexey V. Antonov, Xiaojun Yao, Jean Pierre Doucet,
Botao Fan, F. Hoonakker, D. Fourches, Pierre Jost, Nicolas Lachiche and Alexandre
Varnek;
Benchmarking of Linear and Nonlinear Approaches for Quantitative Structure-Property
Relationship
Studies
of
Metal
Complexation
with
Ionophores
J. Chem. Inf. Model, 2006, 46(2), 808-819.
A. Varnek, D. Fourches, F. Hoonakker, V. P. Solov’ev; Substructural fragments: an
universal language to encode reactions, molecular and supramolecular structures
J. Computer-Aided Molecular Design, 2005, 19, 693-703.
A. Varnek, D. Fourches, V. P. Solov’ev; In silico design of new compounds using
fragment descriptors. In QSAR and Molecular Modelling in Rational Drug Design of
Bioactive Molecules, E. Aki-Sener and I. Yalcin, Eds., CADD&D, Ankara, Turkey, 2004,
342-345
A.Varnek, D. Fourches, V.Solov’ev, D. Fara, A. Katrisky; « “In Silico” Design of New
Uranyl Extractants Based on Phosphoryl-Containing Podands: QSPR Studies, Generation
and Screening of Virtual Combinatorial Library,and Experimental Tests »
J. Chem. Inf. Comput. Sci., 2004, 44: p. 1365-1382.
Atelier GDR PARIS « Base de données », 7 et 8 avril 2004 à l’ULP: conception et
présentation de la séance de travaux pratiques sur les bases de données ChemFinder et
IsisBase. (http://infochim.u-strasbg.fr/recherche/conferences/index.php)
A.Varnek, D. Fourches, V.Solov’ev; « In silico design of new uranyl extractants based on
phosphoryl-containing podands »; livre des abstracts Chimiométrie 2003 (3-4 décembre
2003, Paris), 129-132, Edition Groupe Français de Chimiométrie.
A.Varnek, D. Fourches, V.Solov’ev; « In Silico Design of new extractants for the UO22+
cation »
Présentation lors de la 8ième Rencontre des Chimistes Théoriciens du Grand Est, le 19
Septembre 2003, Nancy.