SHORT BIO – Dr. Chiara Dall`Asta
Transcription
SHORT BIO – Dr. Chiara Dall`Asta
SHORT BIO – Dr. Chiara Dall’Asta 2005 - Research Assistant (SDD: CHIM/10 - Food Chemistry), Faculty of Agriculture, Dep. Organic and Industrial Chemistry, University of Parma 2004 – 2005 PostDoc Fellowship, University of Parma (topic: “Development of switch-on/switch-off luminescence systems for food diagnostic”) 2004 Research stay (6 months), Christian Doppler Laboratory for Mycotoxin Research, Center for Analytical Chemistry at the Dep. IFA Tulln, BOKU – University for Natural Resources and Applied Life Sciences (Vienna, AU) 2004 Doctoral degree in Food Science and Technology, Ph.D. 2000 – 2002 Fellowship granted by Italian Ministry of Health (topic: “New methods for trichothecenes determination in food”) 2000 Professional qualification in Chemistry 1999 Degree in Chemistry, University of Parma Expertise Food chemistry; chemistry of natural substances; xenobiotic analysis and identification; organic trace analysis; mass spectrometry; quantification and strucural characterization of plant and microbial metabolites; multi-analyte-methods (LC-MS/MS) for the simultaneous monitoring of food contaminants; supramolecular chemistry; fluorescence spectroscopy; UV spectroscopy. Main Research Topics - Mass spectrometry based methods for xenobiotics detection. - Identification, characterization and isolation of masked mycotoxins. - Variation of bioactive compounds in foods as a consequence of technological treatments - Development of specific chemosensors based on a “switch on/switch off” luminescence technology for molecular recognition Awards 2008 – Vita International Research Award Award for the best research project concerning honeybees and honeybee-related products. Reviewer for Scientific Journals 2005 - Food Additives and Contaminants (Taylor&Francis) 2006 - Journal of Chromatography A (Elsevier) 2007 - World Mycotoxin Journal (Wageningen Academic Publisher) 2007 - Mycotoxin Research (Springer) 2008 – Journal of the Science of Food and Agriculture (Wiley) Organizer of scientific conferences - “V Congresso Nazionale di Chimica degli Alimenti” – Parma, 2003, June 10 – 12 (participants: 250) - “17th International Symposium on Chiral Discrimination” – Parma, 2005, September 11 – 14 (participants: 300) - “10th International Symposium on immunological, chemical and clinical problems of allergy” – Parma, 2008, May 26 – 29 (participants: 200) Memberships in Professional Societies 2007 – International Society for Mycotoxicology (member) 2004 – German Society for Mycotoxin Research (member) 2001 - Italian Chemistry Society (member) Granted Projects - 2009 – 2012, PRITT – Emilia Romagna “Verifica e controllo contaminazione micotossine: dal campo al prodotto finito (filiera feed)”. Coord: Prof. Arnaldo Dossena. - 2009 – 2012, AGER – Fondazioni in rete per la ricerca agroalimentare: “From seed to pasta: multidisciplinary approach for a more sustainable and high quality durum wheat production”. Coord.:Prof. Gianni Galaverna. - 2008 – 2009, EFSA CFP/EFSA/CONTAM/2008/01: “Scientific information on mycotoxins and natural plant toxicants (MyNAPT)”. Coord: Prof. Paola Battilani. - 2008 – 2011, EU Project “PROgress in Saving Proteins And Recovering Energy (PROSPARE)” (7th Framework Program - FP7-KBBE-2007-1 - Project number 212696). (7FP 2008-2011). Coord: Prof. Arnaldo Dossena. - 2005 – 2006, PRIN: Riconoscimento molecolare chemo- e stereoselettivo di composti biologicamente attivi in sistemi di interesse biologico. Coord.: Prof. Arnaldo Dossena. - 2002 – 2005, PRITT – Emilia Romagna: “Sicurezza e qualità nella filiera dei suini tipici”, Coord: Prof. Arnaldo Dossena. - 2001 – 2003, FIRB – PNR: Nanotecnologie, Microtecnologie, Sviluppo di Materiali. Topic: Studio di microsistemi multifunzionali per determinazioni chimiche e biochimiche in matrici biologiche complesse. Coord.: Prof. Arnaldo Dossena. - 2001 – 2003, Ministero della Salute: “Nuovi metodi per la determinazione dei tricoteceni”. Coord. Prof. Rosangela Marchelli International peer-reviewed publications: 1. E. Chiavaro, C. Dall’Asta, G. Galaverna, A. Biancardi, E. Gambarelli, A. Dossena, R. Marchelli; “ New RPHPLC method to detect aflatoxins in food and feed with cyclodextrins as fluorescence enhancers added to the eluent” Journal of Chromatography A, 2001, 937, 31 – 40. 2. C. Dall’Asta, G. Galaverna, E. Chiavaro, R. Corradini, G. Ingletto, A Dossena, R. Marchelli; “Determination of aflatoxins in food: A new RP-HPLC method based on cyclodextrins as fluorescence enhancers added to the eluent.” Polish Journal of Food and Nutrition Sciences, 2002, 11(SI 2), 95-98. 3. C. Dall’Asta, G. Galaverna, S. Sforza, A Dossena, R. Marchelli; “A new RP-HPLC method for the direct determination of ochratoxin A in wine” Polish Journal of Food and Nutrition Sciences, 2002, 11(SI 2), 92- 94. 4. C. Dall’Asta, R. Corradini, G. Ingletto, G. Galaverna, R. Marchelli; “Fluorescence Enhancement of Aflatoxins Using Native and Substituted Cyclodextrins ”, Journal of Inclusion Phenomena and Macrocyclic Chemistry, 2003, 45, 257 - 263. 5. C. Dall’Asta, G. Galaverna, A. Dossena, R. Marchelli; “A new RP-HPLC method for the determination of ochratoxin A in wine”, Journal of Chromatography A, 2004, 1024, 275 – 279. 6. C. Dall’Asta, G. Galaverna, A. Biancardi, M. Gasparini, S. Sforza, A. Dossena, R. Marchelli; “Simultaneous HPLC-FLD analysis of type A and type B trichothecenes as fluorescent derivatives via reaction with coumarin-3carbonyl chloride”, Journal of Chromatography A, 2004, 1047, 241 – 247. 7. C. Dall’Asta, S. Sforza, G. Galaverna, A. Dossena, R. Marchelli; “Simultaneous detection of type A and type B trichothecenes in cereals by LC-ESI-MS using NaCl as cationization agent”, Journal of Chromatography A, 2004, 1054, 389 – 395. 8. C. Dall’Asta, F. Berthiller, R. Schuhmacher, G. Adam, M. Lemmens, R. Krska; “DON-glycosides: characterization of synthesis products and screening for their occurrence in DON-inoculated wheat samples”; Mycotoxin Research, 2005, 21 (2), 123 – 127. 9. S. Sforza, C. Dall’Asta, A. Moseriti, G. Galaverna, A. Dossena, R. Marchelli; “Alternated Isotope-Coded Derivatization Assay (AIDA): an isotope dilution method applied to the quantification of zearalenone in maize flour”; Angewandte Chemie International Edition, 2005, 44(32), 5126 – 5130 10. Biancardi A., Gasparini M., Dall’Asta C., Marchelli R.; “A rapid multiresidual determination of type A and type B trichothecenes in wheat flour by HPLC-ESI-MS”; Food Additives and Contaminants, 2005, 22(3), 251 – 258 11. F. Berthiller, C. Dall’Asta, R. Schuhmacher, M. Lemmens, G. Adam, R. Krska; „Masked mycotoxins: determination of deoxynivalenol glucoside in artificially and naturally contaminated wheat by liquid chromatography – tandem mass spectrometry”; Journal of Agricultural Food Chemistry, 2005, 53, 3421 – 3425. 12. M. Lemmens, U. Scholz, F. Berthiller, C. Dall’Asta, A. Koutnik, R. Schuhmacher, G. Adam, H. Buerstmayr, Á. Mesterházy, R. Krska, P. Ruckenbauer; “The Ability to Detoxify the Mycotoxin Deoxynivalenol Colocalizes With a Major Quantitative Trait Locus for Fusarium Head Blight Resistance in Wheat”; Molecular PlantMicrobe Interaction, 2005, 18(12), 1318 – 1324 13. C. Dall’Asta, S. Sforza, A. Moseriti, G. Galaverna, A. Dossena, R. Marchelli; “An innovative LC-MS approach applied to the determination of zearalenone in maize flou:r: Alternate Isotope-coded Derivatization Assay (AIDA)”; Mycotoxin Research, 2005, 21(4), 218 – 223. 14. Berthiller F., Krska R. Dall’Asta C., Lemmens M., Adams G., Schuhmacher R.; Determination of DON-3glucoside in artificially and naturally contaminated wheat with LC-MS/MS; Mycotoxin Research, 2005, 21(3), 205 – 208 15. Cucci C., Mignani A.G., Dall’Asta C., Galaverna G., Dossena A., Marchelli R., Pela R.; Proceedings of SPIEThe International Society for Optical Engineering, 2006, 6189, 61892D/1-61892D/5. 16. S.Sforza, C. Dall’Asta, R. Marchelli; “Recent advances in mycotoxin determination in food and feed by hyphenated chromatographic techniques/mass spectrometry; Mass Spectrometry Reviews, 2006, 25, 54 – 76. 17. F. Degola, E. Berni, C. Dall’Asta, E. Spotti, R. Marchelli, I. Ferrero, F.M. Restivo; “Multiplex RT-PCR approach to detect aflatoxigenic strains of Aspergillus Flavus” Journal of Applied Microbiology, 2007, 103, 409 - 417. 18. A. Amadasi, C. Dall’Asta, G. Ingletto, R. Pela, R. Marchelli, P. Cozzini; “Explaining cyclodextrin-mycotoxin interactions using a “natural” force field”. Bioorganic and medicinal Chemistry, 2007, 15, 4585 – 4594 19. C. Cucci, A.G. Mignani, C. Dall’Asta, R. Pela, A. Dossena; “A portable fluorometer for the rapid screening of M1 aflatoxin” Sensors and Actuators B: Chemical, 2007, 126, 467 – 472 20. T. Toscani, A. Moseriti, A. Dossena, C. Dall’Asta, N. Simoncini, R. Virgili; “Determination of ochratoxin A in dry-cured meat products by a HPLC-FLD quantitative method”; Journal of Chromatography, B: Analytical Technologies in the Biomedical and Life Sciences, 2007, 855(2), 242-248. 21. F. Finocchiaro, B. Ferrari, A. Gianinetti, C. Dall'asta, G. Galaverna, F. Scazzina, N. Pellegrini; “Characterization of antioxidant compounds of red and white rice and changes in total antioxidant capacity during processing.”; Molecular nutrition & food research, 2007, 51(8), 1006-19. 22. C. Dall’Asta, G. Galaverna, J. De Dea Lindner, R. Virgili, E. Neviani, A. Dossena. A new validated HPLC-FLD method for detecting ochratoxin A in dry-cured meat and in blue cheese; Mycotoxin Research, 2007, 23(3), 132 – 137. 23. Mignani, A. G.; Ciaccheri, L.; Cucci, C.; Mencaglia, A. A.; Cimato, A.; Attilio, C.; Thienpont, H.; Ottevaere, H.; Paolesse, R.; Mastroianni, M.; Monti, D.; Buonocore, G.; Del Nobile, A.; Mentana, A.; Grimaldi, M. F.; Dall'Asta, C.; Faccini, A.; Galaverna, G.; Dossena, A. Eat-by-light fiber-optic and micro-optic devices for food quality and safety assessment. Proceedings of SPIE-The International Society for Optical Engineering, 2007, 6733, 67331K/1-67331K/13. 24. Mignani, A. G.; Cucci, C.; Ciaccheri, L.; Dall'Asta, C.; Galaverna, G.; Dossena, A.; Marchelli, R. Optical fiber fluorescence spectroscopy for detecting AFM1 in milk. Proceedings of SPIE, 2008, 7004(Pt. 1), 70045S70045S-4. 25. C. Dall'Asta, J. De Dea Lindner, G. Galaverna, A. Dossena, E. Neviani, R. Marchelli; The occurrence of Ochratoxin A in blue cheese; Food Chemistry, 2008, 106, 729 – 734 26. Mignani, A. G.; Ciaccheri, L.; Cucci, C.; Mencaglia, A. A.; Cimato, A.; Attilio, C.; Thienpont, H.; Ottevaere, H.; Paolesse, R.; Mastroianni, M.; Monti, D.; Buonocore, G.; Del Nobile, A.; Mentana, A.; Grimaldi, M. F.; Dall'Asta, C.; Faccini, A.; Galaverna, G.; Dossena, A. Eat-by-light: fiber-optic and micro-optic devices for food quality and safety assessment. IEEE Sensors Journal, 2008, 8 (7), 1 - 13. 27. G. Galaverna, C. Dall’Asta, R. Corradini, A. Dossena, R. Marchelli. Cyclodextrins as selectors for mycotoxin recognition. World Mycotoxin Journal, 2008, 1(4), 397 – 406. 28. C. Dall’Asta, G. Galaverna, G. Aureli, A. Dossena, R. Marchelli. A LC/MS/MS method for the simultaneous quantification of free and masked fumonisins in corn and corn-based products. World Mycotoxin Journal, 2008, 1(3), 1 - 10. 29. D. Giuntini, V. Lazzeri, V. Calvenzani, C. Dall’Asta, G. Galaverna, C. Tonelli, K. Petroni, A. Ranieri. Flavonoid profiling and biosynthetic gene expression in flesh and peel of two tomato genotypes grown under UV-B depleted conditions during ripening. Journal of Agricultural and Food Chemistry, 2008, 56(14), 5905-5915. 30. P. Cozzini, G. Ingletto, R. Singh, C. Dall’Asta. Mycotoxin detection plays “Cops and Robbers”: cyclodextrin chemosensors as specialized police? International Journal of Molecular Science, 2008, 9, 2474 – 2494 31. C. Dall’Asta, G. Galaverna, M. Mangia, S. Sforza, A. Dossena, R. Marchelli. Free and bound fumonisins in gluten-free food products. Molecular Nutrition and Food Research, 2009, 53, 492 – 499 32. F. Berthiller, C. Dall’Asta, R. Corradini, R. Marchelli, M. Suliok, R. Krska, G. Adam, R. Schuhmacher. Occurrence of deoxynivalenol and its 3-D-glucoside in wheat and maize. Food Additives and Contaminants, 2009, 26, 507 – 511 33. G. Galaverna, C. Dall’Asta, M. Mangia, A. Dossena, R. Marchelli. Masked Mycotoxins: an Emerging Issue for Food Safety, Czech Journal of Food Science, 2009, 27, Special Issue, S89 – S92 34. C. Dall’Asta, A. Faccini, G. Galaverna, R. Corradini, A. Dossena, R. Marchelli. Complexation of zearalenone and zearalenols with native and modified b-cyclodextrins. Journal of Inclusion Phenomena and Macrocyclic Chemistry, 2009, 64, 331 – 340 35. C. Dall’Asta, M. Mangia, F. Berthiller, A. Molinelli, M. Sulyok, R. Schuhmacher, R. Krska, G.Galaverna, A. Dossena, R. Marchelli Difficulties in fumonisin determination: the issue of hidden fumonisins. Analitycal and Bioanalytical Chemistry, 2009, 395, 1335 – 1345 36. C. Dall’Asta, C. Falavigna, G. Galaverna, S. Sforza, R. Marchelli. A multiresidual method for the simultaneous determination of the main glycoalkaloids and flavonoids in fresh and processed tomato (Solanum lycopersicum L.) by LC-DAD-MS/MS. Journal of Separation Science, 2009, 32, 1 - 8. 37. C. Dall’Asta, G. Galaverna, T. Bertuzzi, A. Moseriti, A. Pietri, A. Dossena, R. Marchelli. Occurrence of Ochratoxin A in raw ham muscle, salami and dry-cured ham from pigs fed with contaminated diet. Food Chemistry, 2009, in press, DOI: 10.1016/j.foodchem.2009.11.036 38. V. Calvenzani, M. Martinelli, V. Lazzeri, D. Giuntini, C. Dall’Asta, G. Galaverna, C. Tonelli, A. Ranieri, K. Petroni. Response of wild-type and high pigment-1 tomato fruit to UV-B depletion: flavonoid profiling and gene expression. Planta, 2009, in press, DOI 10.1007/s00425-009-1082-4. 39. E. Bergamini, D. Catellani, C. Dall’Asta, G. Galaverna, A. Dossena, R. Marchelli, M. Suman. Fate of Fusarium mycotoxins in cereal product supply chain: the DON case within industrial bread-making technology. Food Additives and Contaminats, 2010, in press