Thyroid Screening and Congenital Hypothyroidism at Khon Kaen

Khon Kaen Hospital Medical Journal Vol. 32 Supplement 3 April - May 2008
165
Thyroid Screening and Congenital Hypothyroidism
at Khon Kaen Hospital
Chatchai Suesirisawad M.D., Thai board of Pediatrics
Department of Pediatrics, Khon Kaen Hospital
Abstract
Background Thyroid hormone is critical for normal cerebral and growth development in the
early postnatal months. The diagnosis must be made soon after birth and effective treatment must be
initiated promptly to prevent irreversible brain damage.
Objective To study of abnormal thyroid screening and incidence of congenital hypothyroidism
including average age of onset of initial treatment in newborn admitted at Department of
Pediatrics, Khon Kaen Hospital was carried out from October 1, 2002 to September 31, 2007
Research design and methods A retrospective study.
Results There were 19,521 live births of which, 18,798 cases were screened (96.30%).
Fifty nine newborns had abnormal thyroid screening, 13 of these were congenital hypothyroidism.
The incidence of congenital hypothyroidism was 1:1,501 live births. The average age of onset of
initial treatment was 49.54 ± 30.73 days.
Conclusion There was high incidence of congenital hypothyroidism and most of newborn
had delay hormone replacement therapy.
Keyword : Thyroid screening, Congenital hypothyroidism, Newborn
166
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Khon Kaen Hospital Medical Journal Vol. 32 Supplement 3 April - May 2008
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