MAIGNE Lydia
Transcription
MAIGNE Lydia
MAIGNE Lydia, PhD, HDR : associate professor in medical physics, University Blaise Pascal – LPC UMR6533 CNRS/IN2P3, Clermont-Ferrand (France) since 1st September 2006. Date of birth : 26/08/79 Nationality : French Marital status : single PCSV team, Laboratoire de Physique Corpusculaire UMR 6533 CNRS/IN2P3 - Université Blaise Pascal 24 avenue des Landais, BP 80026 63171 Aubière cedex, France Tel: (33) (0) 4 73 40 51 23 mobile: (33)(0) 6 87 33 86 40 fax: (33)(0) 4 73 26 45 98 email: [email protected] team : http://pcsv.fr Statistics (June 2014, Google scholar): Citations h index All 1364 11 Since 2009 914 10 EDUCATION UNIVERSITY BLAISE PASCAL/LABORATOIRE DE PHYSIQUE CORPUSCULAIRE UMR 6533 CNRS/IN2P3, CLERMONT-FERRAND (FRANCE) 2013 Habilitation for research supervision (HDR) INSTITUT NATIONAL DES SCIENCES ET TECHNIQUES NUCLEAIRES INSTN-CEA SACLAY (FRANCE) 2006 Medical physics graduate LÉON BÉRARD CANCER CENTRE, LYON (FRANCE) 2005/2006 Trainee medical physicist. Completed basic professional training in Medical Physics UNIVERSITY BLAISE PASCAL/LABORATOIRE DE PHYSIQUE CORPUSCULAIRE UMR 6533 CNRS/IN2P3, CLERMONT-FERRAND (FRANCE) 2002/2005 PhD in particle physics (07/11/2005) Thesis title: Personalized dosimetry using GATE Monte Carlo simulations on a grid architecture. Application in ocular brachytherapy. UNIVERSITY PAUL SABATIER, TOULOUSE III (FRANCE) 2001/2002 Master 2 in medical physics UNIVERSITY BLAISE PASCAL, CLERMONT-FERRAND (FRANCE) 2000/2001 Master 1 in physics and chemistry 1997/2000 Licence in physics and chemistry RESEARCH ACTIVITIES: GRANTS and RESPONSABILITIES (current) June 2013: Coordinator of the RACE project (RAdiation resistance of Cancer CElls using GEANT4 DNA).2 years project funded by the Physics, Mathematics and Engineering sciences applied to the Cancer Research national program (PhysiCancer 2013) 1 2012: Member of the laboratory of Excellence (LabEx) PRIMES (Physics, Radiobiology, Medical Imaging and Simulation). Activities in WP5: Modeling and Simulation January 2012 : Coordinator of the DOGME project (DOsimetry through GATE Monte Carlo simulations for an innovative targeted radionuclide therapy of MElanoma). 2 years project funded by the Physics, Mathematics and Engineering sciences applied to the Cancer Research national program (PhysiCancer 2011) April 2011: Coordinator of the GINSENG project (Global Initiative for Sentinel E-health Network on Grid, http://e-ginseng.org). 3 years project funded by the French National Research Agency (ANR) to enable a grid sentinel network for e-health, epidemiology and health watch. January 2010 : Team manager of the Computing Platform for Life Sciences group (http://pcsv.fr) July 2009 : Coordinator of the Sentinel Network for cancer surveillance in Auvergne. Grid infrastructure dedicated to cancer screening and epidemiology in Auvergne. Member of the GEANT4 DNA steering committee for the development of DNA models and the validation of EM physic processes at very low energy. Member of the OpenGATE steering committee for the development of a Monte Carlo simulation platform based on GEANT4 dedicated to SPECT, PET and radiation therapy. (http://www.opengatecollaboration.org) Development and validation of the platform for radiation therapy using electrons and photons Member of the scientific council of Laboratory of Excellence (LabEx) P2IO (Physique des 2 Infinis et des Origines) Member of EGI (Enabling Grids for E-science) project and member of the French National Grid Initiative Responsible for the partnership with industries for the Laboratoire de Physique Corpusculaire AWARDS December 2010: IN2P3 valorization prize for the applied research of the PCSV team on biomedical informatics on grid, on in-silico drug discovery, and on the sentinel grid network for cancer surveillance in Auvergne. November 2009 : Citation prize for the OpenGATE collaboration paper “GATE: a simulation toolkit for PET and SPECT”, Phys. Med. Biol., 49 (2004) 4543-4561” that has received the largest number of citations in the preceding five years in Physics in Medicine and Biology. 2 TEACHING ACTIVITIES (200 hours/year) University Blaise Pascal: Department of Thermodynamics and Energy Mathematics and physics courses Master 2 in Nuclear Physics and Medical Physics Medical physics courses : Monte Carlo calculations, particle interactions, medical imaging GRADUATE STUDENT SUPERVISION & CO-SUPERVISION: MASTER (18) AND PhD (4) Master 2 in medical physics : 2014 – Dosimetry studies using the GATE platform for preclinical radioimmunotherapy treatments of carcinoma. 2013 – Modeling of a Varian Novalis TX (15MV) linac for dynamic arctherapy using the Monte Carlo simulation platform GATE in a grid environment. – Potentiation of targeted therapy for breast cancer: microdosimetry using GATE-G4DNA Monte Carlo simulations 2012 – Modeling of a Varian Novalis TX (6MV) linac for dynamic arctherapy using the Monte Carlo simulation platform GATE in a grid environment. 2011 – Dosimetry in ocular brachytherapy using 106Ru ophthalmic applicators: GATE Monte Carlo simulations and experimental measurements using radiochromic films. – Dosimetry through GATE Monte Carlo simulations based on mouse CT scans for innovative targeted radionuclide therapy of melanoma. 2010 – Dosimetry in radiation therapy using electrons and photons: GATE Monte Carlo simulations. Validation with experimental measurements and treatment plans using ISOGray TPS. – Dosimetry in radiation therapy using electrons: experiments using different detectors (diode, thermoluminescence and ionization chamber) – Dosimetry through GATE Monte Carlo simulations based on mouse digital phantoms for innovative targeted radionuclide therapy of melanoma. 2009 – GATE Monte Carlo simulation in radiation therapy, simulation of a VARIAN linac and comparisons with IsoGray treatment planning system. – Experimental measurements of dose deposited in anthropomorphic phantoms in radiation therapy using radiochromic films – Optimization of quality control for ocular brachytherapy treatments using ruthenium 106 2008 – Measurements and quality control using radiochromic films for ocular brachytherapy using ruthenium 106. 2007 – GATE Monte Carlo simulation of small animal SPECT scans using iodine 131. Engineer school in computer science: 2014 – Evaluation of computing time efficiency of many integrated core architecture for Geant4/GATE multi-threaded applications 2012 – Implementation of an identification algorithm on GP-GPU architecture 2011 – Interoperability of distributed databases within the GINSENG project 2010 – Authentication on a distributed network using healthcare smart cards for the GINSENG project 3 PhD thesis: 2012-2015 – Sébastien Cipière A mediation system in the medical community based on engineering models and ontologies and using the Common Warehouse Metamodel. 2011-2014 – Trung Quang Pham Validation of physical and radiochemical models involved in DNA irradiation using the GEANT4 DNA software in a grid environment 2009-2011 - Yann Perrot Evaluation of the dose deposited by electron irradiation in voxelized phantoms using GATE and GEANT4 on the grid 2008-2011 – Paul De Vlieger Creating a management of distributed medical databases in a grid environment. Application to the exchange of medical data. 2004-2007 – Cheick Oumar Thiam Dosimetry in radiation therapy and brachytherapy using Monte Carlo simulations on a grid architecture PUBLICATIONS (15) S. Incerti, M. Psaltakic, P. Gilleta, Ph. Barbereta, M. Bardiès, M.A. Bernal, M.-C. Bordage, V. Breton, M. Davidkovag, E. Delage, Z. El Bitar, Z. Francis, S. Guatelli, A. Ivanchenko, V. Ivanchenko, l, M. Karamitros, S.B. Lee, L. Maigne, S. Meylan, K. Murakami, P. Nieminen, H. Payno, Y. Perrot, I. Petrovic, Q.T. Pham, A. Ristic-Fira, G. Santin, T. Sasaki, H. Seznec, J.I. Shin, V. Stepan, H.N. Tran, C. Villagrasa, The Geant4-DNA Collaboration, 15 August 2014 Simulating radial dose of ion tracks in liquid water simulated with Geant4-DNA: A comparative study NIM B: Beam Interactions with Materials and Atoms 333 92-98. (IF 1.266) D. Sarrut, M. Bardies, N. Boussion, N. Freud, S. Jan, J-M. Létang, G. Loudos, L. Maigne, S. Marcatili, T. Mauxion, P. Papadimitroulas, U. Pietrzyk, C. Robert, D R. Schaart, D. Visvikis, I. Buvat, January 2014 An analysis of the potential of GATE for radiation therapy and dosimetry applications accepted for publication in Med. Phys. (IF 2.911) Y. Perrot, F. Degoul, P. Auzeloux, M. Bonnet, F. Cachin, J.M. Chezal, D. Donnarieix, P. Labarre, N. Moins, J. Papon, L. Rbah-Vidal, A. Vidal, E. Miot-Noirault and L. Maigne 2014 Internal dosimetry through GATE simulations of preclinical radiotherapy using melanin-targeting ligand Phys. Med. Biol. 59 (2014) 2183-2198. (IF 2.701) V. Breton, C. Champion, Z. El Bitar, M. Karamitros, S. B. Lee, L. Maigne, Y. Perrot, Q. T. Pham, J. I. Shin, H. N. Tran and S. Incerti 2013 Extending Geant4 at the physics-medicine-biology frontier accepted for publication in Trends in Computational Science and Engineering F. Degoul, M. Borel, N. Jacquemot, S. Besse, Y. Communal, F. Mishellany, J. Papon, F. PenaultLlorca, D. Donnarieix, M. Doly, L. Maigne, E. Miot-Noirault, A. Cayre, J. Cluzel, N. Moins, J-M Chezal, M. Bonnet 2013 In vivo efficacy of melanoma internal radionuclide therapy with a 131Ilabelled melanin-targeting heteroarylcarboxamide molecule Int J Cancer 2013 133 (5) 1042–1053. (IF 5.44) S Jan, D Benoit, E Becheva, T Carlier, F Cassol, P Descourt, T Frisson, L Grevillot, L Guigues, L Maigne, C Morel, Y Perrot, N Rehfeld, D Sarrut, D R Schaart, S Stute, U Pietrzyk, D Visvikis, N Zahra, 4 I Buvat 2011 GATE V6: a major enhancement of the GATE simulation platform enabling modelling of CT and radiotherapy Phys. Med. Biol. 56 881-901. (IF 2.701) L Maigne, Y Perrot, D R Schaart, D Donnarieix, V Breton 2011 GATE/GEANT4 validation for monoenergetic electron dose point kernels and pencil beam kernels between 15 keV and 20 MeV 2011 Phys. Med. Biol. 56 811-827. (IF 2.701) C. Quantin, G. Coatrieux, F. A. Allaert, M. Fassa, K. Bourquard, J-Y. Boire, P. De Vlieger, L. Maigne, Vincent Breton 2009 New advanced technologies to provide decentralised and secure access to medical records: case studies in Oncology Cancer Informatics 7 217–229. (IF 1.6406) V. Breton, A. Da Costa, P. De Vlieger, Y-M Kim, L. Maigne, R. Reuillon, D. Sarramia, T. N. Hai, H. Q. Nguyen, D. Kim, Y.-T. Wu 2009 Innovative in silico approaches to address avian flu using grid technology Innovative in silico approaches to address avian flu using grid technology, Infectious Disorders – Drug Targets 9 (3) 358-365. (IF 2.052) C. Thiam, V. Breton, D. Donnarieix, B. Habib and L. Maigne 2008 Validation of dose deposited by low energy photons using GATE/GEANT4 2008 Phys. Med. Biol. 53 3039-3055. (IF 2.701) C.O. Thiam, L. Maigne, B. Habib, D. Donnarieix, J.Arnold, V. Breton 2007 Simulation Monte Carlo des dépôts de doses en radiothérapie et curiethérapie et déploiement sur grille de calcul Radioprotection 42 43-64. (IF 0.444) L.Maigne, D. Hill, P. Calvat, V. Breton, R. Reuillon, D. Lazaro, Y. Legré, D. Donnarieix Parallelization of Monte Carlo Simulations and Submission to a Grid Environment 2004 Parallel Processing Letters journal 14 (2) 177-196. S. Jan, G. Santin, D. Strul, S. Staelens, K. Assié, D. Autret, S. Avner, R. Barbier, M. Bardiès, P.M. Bloomfield, D. Brasse, V. Breton, P. Bruyndonckx, I. Buvat, A.F. Chatziioannou, Y. Choi, Y.H. Chung, C.Comtat, D.Donnarieix, L.Ferrer, S.J. Glick, C.J. Groiselle, D. Guez, P.-F. Honoré, S. Kerhoas-Cavata, A.S. Kirov, V. Kohli, M. Koole, M. Krieger, D.J. van der Laan, F. Lamare, G. Largeron, C. Lartizien, D. Lazaro, M.C. Maas, L. Maigne, F. Mayet, F. Melot, C. Merheb, E. Pennacchio, J. Perez, U. Pietrzyk, F.R. Rannou, M. Rey, D.R. Schaart, C.R. Schmidtlein, L. Simon, T.Y. Song, J.-M. Vieira, D. Visvikis, R. van de Walle, E. Wieërs, and C. Morel 2004 GATE: a simulation toolkit for PET and SPECT Phys. Med. Biol. 49 4543-4561. (IF 2.701) (2009 PMB Prize for the Highest cited paper) J. Montagnat, F. Bellet, H. Benoit-Cattin, V. Breton, L. Brunie, H. Duque, Y. Legré, I.E. Magnin, L. Maigne, S. Miguet, J.-M. Pierson, L. Seitz, T. Tweed 2004 Medical images simulations, storage, and processing, on the European DataGrid testbed Journal of Grid Computing 2 387-400. (IF 1.31) D. Lazaro, I. Buvat, G. Loudos, D. Strul, G. Santin, N. Giokaris, D. Donnarieix, L. Maigne, V. Spanoudaki, S. Styliaris, S. Staelens and V. Breton 2004 Monte Carlo simulation of a CsI(Tl) gamma camera dedicated to small animal imaging using GATE Phys. Med. Biol. 49 271-285. (IF 2.701) 5 CONFERENCES WITH PROCEEDINGS (26) F Degoul, Y. Perrot, C. Viallard, E. Jouberton, C.Valla , C. Millardet, L. Maigne, J.M. Chezal, E. MiotNoirault, F. Cachin. Dosimetry studies for the clinical transfer of targeted radiotherapy with [131I]ICF01012 for pigmented melanoma metastases treatment, EANM 2014 27th Annual Congress of the European Association of Nuclear Medicine, Gothenburg, Sweden. S. Cipière, D. R. C. Hill, T. Glatard, F. Cervenansky, N. Boujelben, G. Ereteo, J. Montagnat, A. Gaignard, S. Gaspard, J. Revillard, D. Manset, L. Maigne. Global Initiative for Sentinel e-Health Network on Grid (GINSENG). Medical data integration and semantic developments for epidemiology, accepted in CCGrid 2014 - 14th IEEE/ACM International Symposium on Cluster, Cloud and Grid Computing, May 26-29, 2014, Chicago, IL, USA. X. Li, A. Guttman, S. Cipiere, L. Maigne, J. Demongeot, J-Y Boire, L. Ouchchane, Implementation of an Extended Fellegi-Sunter Probabilistic Record Linkage Method Using the Jaro-Winkler String Comparator, accepted in IEEE-EMBS International Conferences on Biomedical and Health Informatics, June 1-4, 2014, Valencia, Spain S. Cipière, P. De Vlieger, D. Sarramia, D. R. C. Hill, L. Maigne, Development of a metamodel for medical database management on a grid network. Application to Health Watch and epidemiology for cancer and perinatal health, 12th IEEE/ACM International Symposium on Cluster, Cloud and Grid Computing,p 892-897, ISBN: 978-0-7695-4691-9, Ottawa, Canada, May 2012. Sarramia, D., L. Maigne, V. Breton, L. Deroussi and B. Louvet, "Simulation Approach for Systems Radiation Biology", in Proceedings of the 25th European Simulation and Modeling Conference (ESM), Guimaraes, 2011, p. 381-386. Y. Perrot, D. Donnarieix, V. Breton and L. Maigne, Validation of GATE 6.0/GEANT4 for radiation therapy dosimetry. Impact of simulation parameters on dose calculation. International Workshop on Recent Advances in Monte Carlo Techniques for Radiation Therapy, Montreal, Québec, Canada, June 2011. Y. Perrot, V. Breton, D. Donnarieix and L. Maigne, Radiotherapy monte carlo dosimetry using GATE/GEANT4 : validation study in anthropomorphic phantom, proceedings of ESTRO conference 2010, Radiotherapy & Oncology, volume 96, Supplement 1, S491, Barcelona, September 2010. P. De Vlieger, J-Y. Boire, V. Breton, Y. Legre, D. Manset, J. Revillard, D. Sarramia and L. Maigne, Sentinel e-health network on grid: developments and challenges, proceedings of HealthGrid 2010 conference, Studies in Health Technology and Informatics 2010, 159: 134-146, Paris, July 2010. P. De Vlieger, J Y Boire, V Breton, L Maigne, D Manset, J Revillard, Cancer Sentinel project: a grid network for distributed medical data management on Cancer, proceedings of the 5th EGEE User Forum, Upssala, March 2009. 6 Y. Perrot, V. Breton, D. Donnarieix and L. Maigne, “Validation of electron radiotherapy beams using GATE/GEANT4 in voxelised phantoms”, proceedings of the European Workshop on Monte Carlo Treatment Planning, Cardiff, October 2009. U. Quast, T.W. Kaulich, A. Ahnesjö, J.T. Alvarez-Romero, M. Andrássy, M. Bambynek, D. Donnarieix, D. Flühs, F. Hensley, H.M. Kramer, L. Maigne, D.C. Medich, F. Mourtada, E. Schüle, H.J. Selbach, C. Soares, E. van Dijk, G.A. Zakaria, “Need for International Standardization of Clinical Dosimetry for Photon Radiation Sources for Brachytherapy and Calibration in Terms of Absorbed Dose to Water”, proceedings of the Medical physics and biomedical engineering World congress, IFMBE proceedings, vol 25, Munich, September 2009. Y. Perrot, V. Breton, V. Chassin, D. Donnarieix and L. Maigne, “Validation of electron radiotherapy beams using GATE/GEANT4 in voxelised phantoms”, Radiotherapy & Oncology, Volume 92 Supplement 1, p S71, ESTRO conference, Maastricht, August 2009. P. De Vlieger, J-Y. Boire, V. Breton, Y. Legré, D. Manset, J. Revillard, D. Sarramia, L. Maigne, « Gridenabled sentinel network for cancer surveillance », proceedings of HealthGrid 2009 conference, Stud Health Technol Inform. 2009; 147:289-94, Berlin, July 2009. Diarena M, Nowak S, Boire JY, Bloch V, Donnarieix D, Fessy A, Grenier B, Irrthum B, Legré Y, Maigne L, Salzemann J, Thiam C, Spalinger N, Verhaeghe N, de Vlieger P, Breton V., « HOPE, an open platform for medical data management on the grid. », proceedings of HealthGrid 2008 conference, Stud. Health Technol. Inform. 2008;138:34-48, Chicago, June 2008. L.Maigne, C.O. Thiam, D. Donnarieix, V. Breton, « Beta ray point source dose distributions using GATE/GEANT4. Application to a 106Ru ocular brachytherapy treatment », Radiotherapy and Oncology, vol. 88, supplement 2, p 403, ISSN 0167-8140, September 2008. M. Diarena, L. Maigne, S. Nowak, V. Breton, « Grid based telemedecine application for Monte Carlo dosimetric studies », EGEE’07 conference, Budapest, Hongrie, 1 - 4 October 2007 L.Maigne, V. Breton, D. Donnarieix, Z. Elbitar, A. Fessy, C.O. Thiam, « Développement d'un système d'information pour l'utilisation d'images médicales pour les simulations Monte Carlo GATE sur grille de calcul », Bulletin du cancer, Vol. 94, p32-33, numéro spécial, March 2007. L.Maigne, D. Donnarieix, C.O. Thiam, V. Breton, R. Barbeira, A. Falzone, “GATE Simulation for medical physics with the Genius portal”, Challenges and Opportunities of Healthgrids Proceedings of Healthgrid 2006, (vol. 120) Studies in Health Technology and Informatics, p 392, ISBN 1-58603617-3, Valencia 2006. D. Donnarieix, L. Maigne, C.O.Thiam, F. Bacin, V. Breton, « Curiethérapie oculaire : Dosimétrie par simulations GATE sur grille de calcul », Bulletin du cancer, Vol. 93, p142, March 2006. D. Visvikis, M. Bardiès, S. Chiavassa, C. Danford, A. Kirov, F. Lamare, L. Maigne, S. Staelens, R. Taschereau, “Use of the GATE Monte Carlo package for dosimetry applications”, International Conference on Imaging Technologies in Biomedical Sciences (ITBS) 2005, Nuclear Instruments and Methods in Physics Research A 569 (2006) 335-340. 7 S. Staelens, J. De Beenhouwer, D. Kruecker, L. Maigne, F. Rannou, L. Ferrer, Y. D’Asseler, I. Buvat, I. Lemahieu, “GATE: improving the computational efficiency”, International Conference on Imaging Technologies in Biomedical Sciences (ITBS) 2005, Nuclear Instruments and Methods in Physics Research A 569 (2006) 341-345. L. Maigne co-author part of the HealthGrid White Paper collaboration, “The HealthGrid White Paper”: chapter 4 on Computational Models of the Human Body, and demonstration on “Parallel Submissions of GATE Monte Carlo simulations to the EGEE Grid Infrastructure using the Genius web portal”, From Grid to Healthgrid, Proceedings of HealthGrid 2005, Studies in Health Technology and Informatics (vol. 112) IOS Press ISBN: 1-58603-510-X, 2005. V. Breton, C. Blanchet, Y. Legré, L. Maigne & J. Montagnat, “Grid technology to biomedical applications”, Proceedings of High Performance Computing for Computational Science, VECPAR 2004 conference, 28-30 June 2004, Valencia, Spain, Lecture Notes in Computer Science vol 3402 , edition Springer (2005) 204-218. L.Maigne, D. Donnarieix, V. Breton, « Parallelization of Monte Carlo simulations and submission to a grid environment », Healthgrid conference 2004, abstract booklet, Clermont-Ferrand. L. Berger, V. Breton, D. Donnarieix, D. Lazaro, L. Maigne, “Computation of P1 problem using the Monte Carlo code GATE” in Intercomparison on the usage of computational codes in radiation dosimetry, QUADOS Conference, 14-16 July 2003, Bologna, Italy, proceedings G. Gualdrini and P. Ferrari Editors p 93-98, 2004. L. Maigne, D. Donnarieix, V. Breton, Y. Legré, “Use of a calculation grid to run Monte Carlo simulation programs with the Geant4 Software in ocular brachytherapy”, 42èmes journées scientifiques de la SFPM, Juin 2003, Reims, France, proceedings dans Physica Medica, Vol. XIX, N°3, July-September 2003. BOOKS OR BOOK CHAPTERS (2) Breton V, Maigne L, Sarramia D and Hill D, Collaborative Computational Technologies for Biomedical Research, Wiley Series on Technologies for the Pharmaceutical Industry Sean Ekins, Series Editor, Hoboken: John Wiley & Sons, ISBN: 978-0-470-63803-3, 2011 L. Maigne co-author part of the HealthGrid White Paper collaboration, “The HealthGrid White Paper”: chapter 4 on Computational Models of the Human Body, and demonstration on “Parallel Submissions of GATE Monte Carlo simulations to the EGEE Grid Infrastructure using the Genius web portal”, From Grid to Healthgrid, Proceedings of HealthGrid 2005, Studies in Health Technology and Informatics (vol. 112) IOS Press ISBN: 1-58603-510-X, 2005. INVITED TALKS IN INTERNATIONAL SYMPOSIUMS (11) 2010: Débat public : comment utiliser les données de santé? Le Réseau Sentinelle Cancer Auvergne Conférence Nationale de Santé, Clermont-Ferrand, February 2010. Biomed activities in France 8 International Workshop on Grid computing applications for Vietnam, Hanoï, December 2010 2009: GATE/GEANT4 simulations on the EGEE grid infrastructure BEGRID conference, Brussels, October 2009 HOPE: HOspital Platform for E-health, EGEEIII User Forum, Catania, March 2009 AuverGrid, a regional grid initiative EGEEIII User Forum, Catania, March 2009 2008: Life sciences applications on a computing grid infrastructure CampusGrid conference, Vienne (Autriche), February 2008 2007: Geant4 simulations using grid computing Geant4 tutorial conference, Paris, June 2007 Life sciences applications on a computing grid infrastructure EUMedGrid workshop, Malte, November 2007 Life sciences applications on a computing grid infrastructure EUMedGrid workshop, Tunis, November 2007 2004 : HealthGrid Four seas conference, Istanbul, September 2004 GATE a simulation toolkit for PET and SPECT Geant4 workshop, Catania, October 2004 TEACHING IN INTERNATIONAL SCHOOLS (8) 2013: Training course on GATE Monte Carlo simulation platform, Seoul, South Korea, December 2013. 2012: Training course on GATE and Grid computing, Alger, Algeria, May 2012. 2011: GATE/GEANT4/Grid tutorial, training course on GATE, GEANT4 and Grid computing, Seoul, Korea, November 2011. 2010: GATE tutorial and Grid tutorial Summer training course on GATE, GEANT4 and Grid computing, Seoul, Korea, July 2010. 9 2009 : GATE on the Grid Geant4 tutorial, Dakar, Sénégal, October 2009. GATE tutorial, Geant4 tutorial, ROOT tutorial Do-Son ACGRID school, Hanoï, Vietnam, September 2009 GATE/GEANT4 simulations on the EGEE grid infrastructure Biomed Grid school, Varenna, May 2009 Medical physics courses PREFALC program (Programme Régional France – Amérique latine – Caraïbes), in Bogota (Columbia) and Lima (Perou), February 2009. 10