Organic Pharmaceutical Chemistry (Pharma Connexion Toxico)

Liaison Entreprises et Universités
Université libre de Bruxelles
Faculté de pharmacie
Organic Pharmaceutical Chemistry

anticancer phenols and polyphenols, asymmetric synthesis, atherosclerosis,
inflammation, medicinal chemistry and organic synthesis of bioactive molecules, organic
synthesis, platinum complexes, serotonin, Anesthetics, Cancer, Myeloperoxidase
Questions ?
Patrick Di Stefano
Conseiller scientifique - Biotech
 +32-026509656
 [email protected]
Laboratory contact details
Laboratory Head
General Contact
Prof. Nève Jean
 Boulevard du
Triomphe
1050 Brussels
Belgique
 +32-026505177
 [email protected]
Main study areas and research topics
Medicinal Chemistry & Drug design: rationale design of new lead compounds in the above-mentionned fields of
research or in others (propose by collaborators)
Organic synthesis for Biological and Pharmaceutical Purposes (University Research & Industry) : custom-synthesis
of bioactive compounds
Determination of antioxidant and trace elements in biological samples (for University and Industry)
Trace elements & micronutriments in medicine
Last Research Project
Anticancer Pt(II) complexes: very potent chiral cytotoxic Pt(II) complexes
Phenolic & Polyphenolic anticancer molecules (Kinases inhibitors) with potential use in apoptosisresistant cancers
Myeloperoxidase inhibitors as potential drugs for atherosclerosis and other inflammatory syndromes
Study of the effect of remifentanyl on allodynia and CNS development
Rationale design of serotonin reuptake inhibitors as antidepressant candidates
Industrial application fields
More information about the Universities & Higher Education Institutions expertise on www.reseaulieu.be
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Liaison Entreprises et Universités
Industrial application fields
Development of new bioactive molecules for Pharmaceutical Industry
Discovery of new therapeutical targets
Technologies offers description
HPLC and LC-MS-MS (QTOF) Automated organic synthesis device (Easymax, Mettler) Fluorimeter, FT-IR and UV
spectrophotometers Atomic absorption spectrophotometer Microwave-oven for synthesis and biological matrix digestion
(Start S, Milestone) Flas
Extraordinary engineering equipments
LC system coupled to a QTOF 6520 for mass spectrometry analysis with high resolution and mass accuracy
Services proposal
Custom organic synthesis Analysis of biological or organic samples Analytic developments for pharmaceutical and
biomedical industries
More information about the Universities & Higher Education Institutions expertise on www.reseaulieu.be
Page 2 / 2