THURSDAY 15th JANUARY - SiRIC
Transcription
THURSDAY 15th JANUARY - SiRIC
THURSDAY 15th JANUARY From chromosomes to genes 2:00pm Introduction Christian Bréchot (Institut Pasteur, Paris, France) Agnès Buzyn (Inca, Paris, France) 2:05pm-2:20pm Chairs: Jessica Zucman Rossi (Inserm U1162, Paris, France) Olivier Delattre (Inserm U830, Institut Curie, Paris, France) 2:20pm-3:00pm Timothy Triche (Director, Center for Personalized Medicine, Children Hospital, Los Angeles, USA) Ewing Sarcoma: Genomic insights beyond EWS-FLI1 3:00pm-3:20pm Philippe Grandval (Gastroenterology and oncogenetic, Inserm U910, Hôpital La Timone, Marseille) Inherited colorectal cancer predispositions: development of an integrated tool for interpretation of germline variations 3:20pm-4:00pm Pieter de Jong (Scientist, Children’s Hospital Oakland Research Institute & Director, BACPAC Resources Center, UCSF Benioff Children’s Hospital Oakland) The evolving karyotype of small apes: factors contributing to the relative instability of the gibbon karyotype 4:00pm-4:30pm Coffee break Genetic predisposition 4:30pm-4:40pm Chairs: Stephen Chanock (NCI, Bethesda, USA) Fabien Calvo (Hôpital St Louis, Paris, France) 4:40pm-5:25pm Guy Rouleau (Director of the Montreal Neurological Institute and Hospital, Chair of the Department of Neurology and Neurosurgery, Mc Gill Univ, Montreal, Canada) Lessons learned from cancer applied to the Brain 5:25pm-5:45pm Ziad Albahni (UMR1149, Hôpital Robert Debré, Paris, France) Nod2 and the epithelial barrier function 5:45pm-6:25pm Richard Houlston (Professor of population and Molecular genetics, Cancer Research Institute, London, UK) Polygenic susceptibility to cancer comes of age Reception 7:00pm Piano Récital, Jérôme Granjon Jérôme Granjon was awarded 1st prize for piano and chamber music at the Paris National Conservatoire and won the Città di Senigallia international piano competition. He is often invited to play in recital and with orchestras (Orchestre Philharmonique de Radio-France, Orchestre National de Lille, Moscow Soloists, etc.) in Europe, the USA, Japan and Brazil. Beethoven: Sonate n°17 en ré mineur op.31 n°2 dite "Tempête" (23') Largo - Allegro Adagio Allegretto Janacek: Dans les Brouillards, pièces 1, 3 et 4 (10') Debussy: Pagodes, extrait des Estampes (6') Schumann: Humoresque op.20 (27') 8:10pm Friendly dinner party FRIDAY 16th JANUARY Genes and cancer 9:00am Introduction Thierry Philip (Institut Curie, Paris, France) 9:00am-9:10am Chairs: Marco Giovannini (UCLA, Los Angeles, USA) Pierre Laurent-Puig (HEGP, Paris, France) 9:10am-9:50am Elias Campo (Chief, Hematopathology Unit Professor of Pathology, Hospital Clinic, University of Barcelona, Barcelona, Spain) Chronic lymphocytic leukemia, from genomes to clinics 9:50am-10:05am Jean Charles Nault (Inserm U1162, Paris, France) Viral and non viral mechanisms of malignant transformation in liver carcinogenesis 10:05am-10:45am Andrew Feinberg (Gilman Scholar and Professor, Johns Hopkins University, Baltimore, USA) The Epigenetic Basis of Human Cancer 10:45am-11:15am Coffee break 11:15am11:25am Chairs: Alain Puisieux (CRCL, Centre Léon Bérard, Lyon, France) Anne Vincent-Salomon (Institut Curie, Paris, France) 11:25am-12:05am Stephen Chanock (Director, Division of Cancer Epidemiology & Genetics, NCI, Bethesda, USA) Discovery of cancer susceptibility loci the Gilles way 12:05am-12:45am Serge Jothy (Pathologist at St. Michael’s Hospital, Toronto, and Professor of Pathology at the University of Toronto, Toronto, Canada) A new era in anatomic pathology: lessons we are learning from the expression and function of cancer molecules 12:45am-2:00pm Lunch From next generation sequencing to treatment 2:00pm-2:10pm Chairs: Christian Bréchot (Institut Pasteur, Paris, France) Jean Pierre Hugot (UMR1149, Hôpital Robert Debré, France) 2:10pm-2:50pm Peter Lichter (Head of the Molecular Genetics Division at the German Cancer Research Center/DKFZ, Heidelberg, Germany) Integrative OMICS Analyses of Brain Tumors: Impact on Elucidation of Pathomechanisms and Clinical Translation 2:50pm-3:10pm David Cox (Research Associate, Centre Léon Bérard, Lyon, France) Genetic predisposition: from tumor initiation through disease progression 3:10pm-3:50pm Michael Stratton (Director, Wellcome Trust Sanger Institute, Cambridge, UK) Signatures of Mutational Processes in Human Cancer 3:50pm-4:10pm Thomas Grunewald (Post-Doc, Inserm U830 "Genetics and Biology of Cancers", Institut Curie Research Center, Paris) Germline variation at a polymorphic GGAA-microsatellite predisposes to EWSR1-FLI1-driven tumorigenesis of Ewing sarcoma 4:10pm-4:50pm Thomas Hudson (President and Scientific Director Ontario Institute for Cancer Research, Toronto, Canada) Challenges in Translational Research 4:50pm-5:00pm Concluding remarks Sylviane Olschwang (Gastroenterology and oncogenetic, Inserm U910, Hôpital La Timone, Marseille)