Klinische Kompetenz und Tätigkeit als Kaderarzt an einem

Transcription

Klinische Kompetenz und Tätigkeit als Kaderarzt an einem
Curriculum Vitae
Beat Gloor, MD, Prof. of GI surgery
1 Personal data
Name/First name
Gloor, Beat
2 Professional career
Year
Institution
Function
1987
19881990
1991
Kantonsspital Winterthur; Pathologie
Kantonales Spital Altstätten /SG; Chirurgie und
Orthopädie
Kantonsspital Frauenfeld; Allgemeine-, Gefäss- und
Unfallchirurgie
Regionalspital Herisau, Allgemeine- und
Unfallchirurgie
Kantonsspital Frauenfeld; Allgemeine-, Gefäss- und
Unfallchirurgie
Kantonsspital Luzern; Allgemeine-, Gefäss- und
Unfallchirurgie
Department of Gastrointestinal Surgery; University
of California at Los Angeles (UCLA)
Resident
Resident
1991
1992
19931995
1996
and
1997
2–6
/1998
7/1998
Resident
Senior resident
Registrar
Senior registrar
Research fellow
(davon während 18 Monaten Stipendium des
Schweizerischen Nationalfonds für angehende Forscher)
Universität Bern, Inselspital, Klinik für Viszerale und
Transplantationschirurgie
Universität Bern, Inselspital, Klinik für Viszerale und
Transplantationschirurgie
10/2001 Universität Bern, Inselspital, Klinik für Viszerale und
Transplantationschirurgie
4/2003
Universität Bern, Inselspital, Klinik für Viszerale und
to
Transplantationschirurgie
4/2011
(since July 1,2008 new name and organization:
Universitätsklinik für Viszerale Chirurgie und
Medizin )
Since
Universität Bern, Inselspital, Universitätsklinik für
1.5.2011 Viszerale Chirurgie und Medizin
Senior resident
Senior registrar
Consultant
Senior consultant
Chief staff surgeon
2
3 Academic career
Year
Institution
19801986
1986
1988
1994
12/2001
2003
8/2007
Medical school, University Zürich
Medical faculty University Zürich
Medical faculty University Zürich
Swiss society for Surgery
Medical faculty University Bern
Swiss society for visceral Surgery
Medical faculty University Bern
Notation
Staatsexamen
MD thesis
Board certified
Lecturer (Venia docendi) for Surgery
Excellence in visceral surgery
Associated Professor of Surgery
4 Lectures at international meetings
(extract of some important lectures)

International Consensus Conference on Necrotizing Pancreatitis, Washington DC, USA, April
2004
Prophylactic antibiotics – the other side of the coin

International Society for Digestive Surgery, Marbella, Spanien 13.5.2007
Die nicht im Gesunden erfolgte onkologische Resektion

European Digestive Surgery, Postgraduate course, Kaunas, Littauen, 10.11.2007
Advanced pancreatic cancer: Adjuvant therapy or best supportive care

United European Gastroenterology Week, Wien, Österreich; 18. bis 22.10.2008
Symposium zum Thema Exokrine Pankreasinsuffizienz
Exocrine pancreatic insufficiency following pancreatic head resection

International Society for Digestive Surgery, Brac, Kroatien, 23. bis 27.5. 2009
Neoadjuvante Behandlung beim Pankreaskarzinom

Jahreskongress der Österreichischen Gesellschaft für Chirurgie, Wien, Österreich,20.6.09
Chirurgische Therapiekonzepte beim Pankreaskarzinom

United European Gastroenterology Week, Barcelona, Spanien, 23. - 27.10.2010
Chairman Poster round Surgery / Endoscopy II (26.10.2010)

United European Gastroenterology Week, Barcelona, Spanien, 23. - 27.10.2010
Chairman session: Surgical complications: When to call the endoscopist? (27.10.2010)

European Digestive Surgery, Postgraduate course, Clui, Rumänien, 5. and 6.11.2010
Video-presentation: laparoscopic transgastric cysto-gastrostomy in patients with severe acute
pancreatitis
3

United European Gastroenterology Week, Stockholm Sweden, 22. - 26.10.2011
Chairman Poster round Surgery / Endoscopy II (24.10.2011)

United European Gastroenterology Week, Stockholm Sweden, 22. - 26.10.2011
Chairman session on chronic pancreatitis (23.10.2011)

United European Gastroenterology, Summer school for Gastroenterology, Prague June 7-10,
2012
Management of a pancreatic mass

United European Gastroenterology Week, Amsterdam, The Netherlands, 20. - 24.10.2012
Course director postgraduate course session Management of pancreatic and biliary cancer
(20.10.2012)

United European Gastroenterology Week, Amsterdam, The Netherlands, 20. - 24.10.2012
Chair clinical case session: Gastroenterology and hepatology: upper GI (22.10.2012)

United European Gastroenterology Week, Amsterdam, The Netherlands, 20. - 24.10.2012
Chair lunch session: Adenoma of the papilla vateri: Endoscopic therapy / Surgical therapy
(22.10.2012)

United European Gastroenterology Week, Amsterdam, The Netherlands, 20. - 24.10.2012

Chair lunch session: Management of pancreatic collections (23.10.2012)

Expert participant at the international Consensus conference on Branch duct IPMN, Garda,
Verona, Italy, April.22 and 23, 2013

United European Gastroenterology Week, Oct. 12 – 16, 2013 Berlin, Germany.
Timing of minimal invasive surgery in acute necrotizing pancreatitis.

European Federation of the International Society of Digestive Surgery. Cluj, Romania,
October 30/31, 2014
Cancer of the oesophagus and esophagogastric junction: classification and treatment update.

Deutscher Pankreasclub, Rostock, Germany, Jan 22/23, 2015
Minimal invasive necrosectomy in severe acute pancreatitis

European Digestive Surgery, International postgraduate course, Riga, Latvia, Mai 14-16,
2015
Video session:Laparoscopic liver resection

United European Gastroenterology Week, Oct. 25 – 28, 2015 Barcelona, Spain.
Preoperative management of esophageal obstruction
4
5 Memberships / Awards / Editorial work
1.
2..
3.
4.
5.
6.
7.
Swiss Society of Surgery (SGC)1994
European Digestive Surgery (EDS; 1999)
Society for Surgery of the Alimentary Tract (SSAT; 1999)
Swiss Society for Visceral Surgery (SGVC 2000)
Swiss Association for Laparoscopic and Thoracoscopic Surgery (2001)
Council member European Digestive Surgery EDS (2009-) President of the scientific
committee 1/2010 – 12/2012.
Member scientific committee United European Gastroenterology ueg 12/2009 – 6/2013.
Scientific awards
1. Mai G, Gloor B, Uhl W, Muller CA, Tcholakov O, Büchler MW. Routine antibiotic prophylaxis in
necrotizing pancreatitis increased gram-positive infections. Digestion 1999; 60:389.European
Pancreas Club Award in Clinical Pancreatic Science 1999; Lüneburg, Germany
2. Gloor B, Angst E, Wagner MM, Candinas D. Surgical technique of laparoscopic transgastric
pancreatico-gastrostomy in severe acute pancreatitis. Videopreis der Schweizerischen
Gesellschaft für Viszeralchirurgie 2007
3. Kurmann A, Kolb W, Clerici T, Brändle M,Forrer F, Wild D, Reubi JC, Christ E, Gloor B.
Glucagon-like Peptide 1 (GLP-1) receptor scintigraphy - a novel localization technique for
insulinomas pre- and intraoperatively Felix-Largiader Preis der Schweiz. Gesellschaft für
Viszeralchirurgie 2010
4. Angst E, Kim C, Kaderli R, Gloor B, Candinas D, Reber HA, Eibl G, Hines OJ. Orally
bioavailable quercetin is effective as single and adjunct treatment for pancreatic cancer in vitro
and in vivo. Swiss Surgical Society Meeting 2010 Association for Research in Surgery
Prize: Best oral presentation
Associate Editor Journal Digestive Surgery since 2011
Editorial board member and reviewer for the journal Patient Safety in Surgery since 2007
5
6 Publications
For 2012 until today see:
http://www.ncbi.nlm.nih.gov/pubmed?term=Gloor%20B
Prior to 2012
1. Gloor B. Management of bile duct stones. Invited commentary. Dig Surg 2011;28:432.
2. Angst E, Kim-Fuchs C, Kuruvilla YC, et al. How to counter the problem of R1 resection in
duodenopancreatectomy for pancreatic cancer? J Gastrointest Surg 2012;16:673.
3. Worni M, Witschi A, Gloor B, Candinas D, Laffer UT, Kuehni CE. Early closure of ileostomy is
associated with less postoperative nausea and vomiting. Dig Surg 2011;28:417-23.
4. Kim-Fuchs C, Kuruvilla YC, Angst E, Weimann R, Gloor B, Candinas D. Appendiceal
mucocele in an elderly patient: how much surgery? Case Rep Gastroenterol 2011;5:516-22.
5. Worni M, Akushevich I, Gloor B, et al. Adjuvant radiotherapy in the treatment of invasive
intraductal papillary mucinous neoplasm of the pancreas: an analysis of the surveillance,
epidemiology, and end results registry. Ann Surg Oncol 2012;19:1316-23.
6. Angst E, Kim C, Gloor B, Schweizer T. [Abdominal pain in the general doctor's practice].
Ther Umsch 2011;68:441-3.
7. Deyle S, Banz VM, Wagner M, et al. Estimation of physiologic ability and surgical stress
score does not predict immediate outcome after pancreatic surgery. Pancreas 2011;40:7239.
8. Angst E, Dawson DW, Stroka D, et al. N-myc downstream regulated gene-1 expression
correlates with reduced pancreatic cancer growth and increased apoptosis in vitro and in
vivo. Surgery 2011;149:614-24.
9. Angst E, Hiatt JR, Gloor B, Reber HA, Hines OJ. Laparoscopic surgery for cancer: a
systematic review and a way forward. J Am Coll Surg 2010;211:412-23.
10. Reubi JC, Waser B, Cescato R, Gloor B, Stettler C, Christ E. Internalized somatostatin
receptor subtype 2 in neuroendocrine tumors of octreotide-treated patients. J Clin Endocrinol
Metab 2010;95:2343-50.
11. Christ E, Wild D, Forrer F, et al. Glucagon-like peptide-1 receptor imaging for localization of
insulinomas. J Clin Endocrinol Metab 2009;94:4398-405.
12. Renzulli P, Hostettler A, Schoepfer AM, Gloor B, Candinas D. Systematic review of
atraumatic splenic rupture. Br J Surg 2009;96:1114-21.
13. Pirnia F, Pawlak M, Thallinger GG, et al. Novel functional profiling approach combining
reverse phase protein microarrays and human 3-D ex vivo tissue cultures: expression of
apoptosis-related proteins in human colon cancer. Proteomics 2009;9:3535-48.
14. Quarta M, Stroka D, Keogh A, et al. Multiparameter flow cytometry characterization of MHC
class I negative mouse bone marrow cells. Med Sci Monit 2008;14:BR286-93.
15. Wild D, Macke H, Christ E, Gloor B, Reubi JC. Glucagon-like peptide 1-receptor scans to
localize occult insulinomas. N Engl J Med 2008;359:766-8.
16. Vorburger SA, Gloor B, Candinas D. [Tumor surveillance after resection of colorectal cancer].
Ther Umsch 2008;65:329-34.
17. Sidler D, Studer P, Kupper S, et al. Granulocyte colony-stimulating factor increases hepatic
sinusoidal perfusion during liver regeneration in mice. J Invest Surg 2008;21:57-64.
18. Jenni S, Gloor B, Stettler C, Christ ER. Fact or factitious? Am J Med 2007;120:848-50.
19. Muller CA, Belyaev O, Vogeser M, et al. Corticosteroid-binding globulin: a possible early
predictor of infection in acute necrotizing pancreatitis. Scand J Gastroenterol 2007;42:135461.
20. Wagner M, Gloor B, Ambuhl M, et al. Roux-en-Y drainage of the pancreatic stump decreases
pancreatic fistula after distal pancreatic resection. J Gastrointest Surg 2007;11:303-8.
21. Inderbitzin D, Beldi G, Sidler D, et al. Granulocyte colony-stimulating factor supports liver
regeneration in a small-for-size liver remnant mouse model. J Gastrointest Surg
2007;11:280-5.
22. Uhl W, Gloor B, Buchler MW. Pancreatic surgery. Curr Opin Gastroenterol 1999;15:410-9.
6
23. Angst E, Sibold S, Tiffon C, et al. Cellular differentiation determines the expression of the
hypoxia-inducible protein NDRG1 in pancreatic cancer. Br J Cancer 2006;95:307-13.
24. Pirnia F, Frese S, Gloor B, et al. Ex vivo assessment of chemotherapy-induced apoptosis
and associated molecular changes in patient tumor samples. Anticancer Res 2006;26:176572.
25. Muller CA, Vogeser M, Belyaev O, et al. Role of endogenous glucocorticoid metabolism in
human acute pancreatitis. Crit Care Med 2006;34:1060-6.
26. Beldi G, Ipaktchi R, Wagner M, Gloor B, Candinas D. Laparoscopic ventral hernia repair is
safe and cost effective. Surg Endosc 2006;20:92-5.
27. Inderbitzin D, Avital I, Gloor B, Keogh A, Candinas D. Functional comparison of bone
marrow-derived liver stem cells: selection strategy for cell-based therapy. J Gastrointest Surg
2005;9:1340-5.
28. Inderbitzin D, Muggli B, Ringger A, et al. Molecular absorbent recirculating system for the
treatment of acute liver failure in surgical patients. J Gastrointest Surg 2005;9:1155-61;
discussion 61-2.
29. Renzulli P, Jakob SM, Tauber M, Candinas D, Gloor B. Severe acute pancreatitis: caseoriented discussion of interdisciplinary management. Pancreatology 2005;5:145-56.
30. Frilling A, Stavrou GA, Mischinger HJ, et al. Effectiveness of a new carrier-bound fibrin
sealant versus argon beamer as haemostatic agent during liver resection: a randomised
prospective trial. Langenbecks Arch Surg 2005;390:114-20.
31. Inderbitzin D, Avital I, Keogh A, et al. Interleukin-3 induces hepatocyte-specific metabolic
activity in bone marrow-derived liver stem cells. J Gastrointest Surg 2005;9:69-74.
32. Inderbitzin D, Gass M, Beldi G, et al. Magnetic resonance imaging provides accurate and
precise volume determination of the regenerating mouse liver. J Gastrointest Surg
2004;8:806-11.
33. Gloor B, Stahel PF, Muller CA, Schmidt OI, Buchler MW, Uhl W. Predictive value of
complement activation fragments C3a and sC5b-9 for development of severe disease in
patients with acute pancreatitis. Scand J Gastroenterol 2003;38:1078-82.
34. Rau C, Candinas D, Gloor B. [Technique of pancreatic anastomosis]. Swiss Surg
2003;9:135-9.
35. Gloor B, Stahel PF, Muller CA, Worni M, Buchler MW, Uhl W. Incidence and management of
biliary pancreatitis in cholecystectomized patients. Results of a 7-year study. J Gastrointest
Surg 2003;7:372-7.
36. Gloor B, Worni M, Strobel O, et al. Cefepime tissue penetration in experimental acute
pancreatitis. Pancreas 2003;26:117-21.
37. Gloor B, Ly Q, Candinas D. Role of laparoscopy in hepatic cyst surgery. Dig Surg
2002;19:494-9.
38. Zimmermann A, Gloor B, Kappeler A, Uhl W, Friess H, Buchler MW. Pancreatic stellate cells
contribute to regeneration early after acute necrotising pancreatitis in humans. Gut
2002;51:574-8.
39. Redaelli CA, Wagner M, Krahenbuhl L, et al. Liver surgery in the era of tissue-preserving
resections: early and late outcome in patients with primary and secondary hepatic tumors.
World J Surg 2002;26:1126-32.
40. Gloor B, Schmidt O, Uhl W, Buchler MW. Acute pancreatitis: threat of fungal infection.
Pancreatology 2001;1:213-6.
41. Gloor B, Schmidtmann AB, Worni M, Ahmed Z, Uhl W, Buchler MW. Pancreatic sepsis:
prevention and therapy. Best Pract Res Clin Gastroenterol 2002;16:379-90.
42. Gloor B, Ahmed Z, Uhl W, Buchler MW. Pancreatic disease in the elderly. Best Pract Res
Clin Gastroenterol 2002;16:159-70.
43. Uhl W, Roggo A, Kirschstein T, et al. Influence of contrast-enhanced computed tomography
on course and outcome in patients with acute pancreatitis. Pancreas 2002;24:191-7.
44. Gloor B, Uhl W, Tcholakov O, et al. Hydrocortisone treatment of early SIRS in acute
experimental pancreatitis. Dig Dis Sci 2001;46:2154-61.
45. Stahel PF, Morganti-Kossmann MC, Perez D, et al. Intrathecal levels of complement-derived
soluble membrane attack complex (sC5b-9) correlate with blood-brain barrier dysfunction in
patients with traumatic brain injury. J Neurotrauma 2001;18:773-81.
7
46. Lane JS, Todd KE, Gloor B, et al. Platelet activating factor antagonism reduces the systemic
inflammatory response in a murine model of acute pancreatitis. J Surg Res 2001;99:365-70.
47. Gloor B, Muller CA, Worni M, Martignoni ME, Uhl W, Buchler MW. Late mortality in patients
with severe acute pancreatitis. Br J Surg 2001;88:975-9.
48. Gloor B, Muller CA, Worni M, et al. Pancreatic infection in severe pancreatitis: the role of
fungus and multiresistant organisms. Arch Surg 2001;136:592-6.
49. Gloor B, Schmidt O, Uhl W, Buchler MW. Prophylactic antibiotics and pancreatic necrosis.
Curr Gastroenterol Rep 2001;3:109-14.
50. Gloor B, Friess H, Uhl W, Buchler MW. A modified technique of the Beger and Frey
procedure in patients with chronic pancreatitis. Dig Surg 2001;18:21-5.
51. Gloor B, Uhl W, Muller CA, Buchler MW. The role of surgery in the management of acute
pancreatitis. Can J Gastroenterol 2000;14 Suppl D:136D-40D.
52. Gloor B, Wente MN, Muller CA, Worni M, Uhl W, Buchler MW. [Indications for surgical
therapy and operative technique in acute pancreatitis]. Swiss Surg 2000;6:241-5.
53. Muller C, Uhl W, Gloor B, et al. [Acute pancreatitis--clinical and technical laboratory
diagnostic and prognostic assessment]. Swiss Surg 2000;6:235-40.
54. Gloor B, Blinman TA, Rigberg DA, et al. Kupffer cell blockade reduces hepatic and systemic
cytokine levels and lung injury in hemorrhagic pancreatitis in rats. Pancreas 2000;21:414-20.
55. Buchler MW, Gloor B, Muller CA, Friess H, Seiler CA, Uhl W. Acute necrotizing pancreatitis:
treatment strategy according to the status of infection. Ann Surg 2000;232:619-26.
56. Gloor B, Uhl W, Buchler MW. Changing concepts in the surgical management of acute
pancreatitis. Baillieres Best Pract Res Clin Gastroenterol 1999;13:303-15.
57. Ryder NM, Ko CY, Hines OJ, Gloor B, Reber HA. Primary duodenal adenocarcinoma: a 40year experience. Arch Surg 2000;135:1070-4; discussion 4-5.
58. Shrikhande S, Friess H, Issenegger C, et al. Fluconazole penetration into the pancreas.
Antimicrob Agents Chemother 2000;44:2569-71.
59. Lewis MP, Lo SK, Reber PU, et al. Endoscopic measurement of pancreatic tissue perfusion
in patients with chronic pancreatitis and control patients. Gastrointest Endosc 2000;51:195-9.
60. Muller CA, Uhl W, Printzen G, et al. Role of procalcitonin and granulocyte colony stimulating
factor in the early prediction of infected necrosis in severe acute pancreatitis. Gut
2000;46:233-8.
61. Uhl W, Loffler H, Zimmermann A, Tcholakov O, Gloor B, Buchler MW. [Surgical treatment of
echinococcosis of the liver]. Swiss Surg 1999;5:126-32.
62. Gloor B, Todd KE, Lane JS, Lewis MP, Reber HA. Hepatic Kupffer cell blockade reduces
mortality of acute hemorrhagic pancreatitis in mice. J Gastrointest Surg 1998;2:430-5.
63. Todd KE, Gloor B, Lane JS, Isacoff WH, Reber HA. Resection of locally advanced pancreatic
cancer after downstaging with continuous-infusion 5-fluorouracil, mitomycin-C, leucovorin,
and dipyridamole. J Gastrointest Surg 1998;2:159-66.
64. Gloor B, Todd KE, Lane JS, Rigberg DA, Reber HA. Mechanism of increased lung injury
after acute pancreatitis in IL-10 knockout mice. J Surg Res 1998;80:110-4.
65. Gloor BR. [Risks of 360 degree suture trabeculotomy]. Ophthalmologe 1998;95:100-3.
66. Reber HA, Gloor B. Radical pancreatectomy. Surg Oncol Clin N Am 1998;7:157-63.
67. Todd KE, Lewis MP, Gloor B, Kusske AM, Ashley SW, Reber HA. Management decisions for
unusual periampullary tumors. Am Surg 1997;63:927-32.
68. Todd KE, Lewis MP, Gloor B, Lane JS, Ashley SW, Reber HA. An ETa/ETb endothelin
antagonist ameliorates systemic inflammation in a murine model of acute hemorrhagic
pancreatitis. Surgery 1997;122:443-9; discussion 9-50.
69. Lane JS, Todd KE, Lewis MP, et al. Interleukin-10 reduces the systemic inflammatory
response in a murine model of intestinal ischemia/reperfusion. Surgery 1997;122:288-94.
70. Gloor B, Todd KE, Reber HA. Surgical therapy for pancreatic pseudocysts. J Gastrointest
Surg 1997;1:203-4.
71. Gloor B, Todd KE, Reber HA. Diagnostic workup of patients with suspected pancreatic
carcinoma: the University of California-Los Angeles approach. Cancer 1997;79:1780-6.

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