The-short-form-of-the-endometriosis-health-profile
Transcription
The-short-form-of-the-endometriosis-health-profile
The short form of the endometriosis health profile questionnaire (EHP-5): Evaluating responsiveness to change of the French version and comparison with EQ-5D Abstract ID : 1755 Soumis par : Gabrielle AUBRY Le 2016-03-15 22:38:01 Nom de la catégorie : SEUD CONGRESS Typologie : Communication orale / Oral communication Statut : validé Autorisation de diffusion : Yes/Oui ------------------------------------Purpose The Endometriosis Health Profile 5 (EHP-5) is a short version of an endometriosis-specific quality of life assessment questionnaire. The objective of the study was to confirm construct validity and to evaluate its sensitivity to change, comparing with a general quality of life questionnaire, the EQ-5D. Materials Prospective observational study including 250 symptomatic women with proven endometriosis undergoing surgical or medical treatments, in two French referral centers. The EHP-5 and the EQ-5D were administered before beginning of treatment (time 1) and within 12 months after (time 2). Construct validity was evaluated by testing respectively the relationships of EPH-5 and EQ-5D with endometriosis? or patient?s characteristics. To evaluate and compare responsiveness to change, mean effect size of each scale was calculated overall and in each treatment group separately. Results 232 patients were analyzed at time 1, 188 in the surgical group and 44 in the medical one. 18 patients didn?t filled in one of the two questionnaires at this time. The EHP-5 was sensitive to posterior location with ES= 0,48 (95%CI =0,06-0,89), severity of the disease especially intestinal attempt with ES= 0,65 (95%IC= 0,08-1,21) and pain as the main complaint ES =1,32 (95%CI =0,83-1,79). The EQ5D was also sensitive to the presence of intestinal attempt ES= 0,55 (95% IC= 0,05-1,05) and pain ES= 1 (0.59-1.39), but in a lesser extent. 139 patients returned the questionnaire at time 1 and 2. Overall mean effect size for responsiveness to change of EHP-5 scale was 0,83 (95%IC = 0,54- 1, 11) compared to 0,81 (95%IC =0,56-1, 06) for EQ-5D. For the patients who underwent surgical treatment, the EHP-5 also proved good sensitivity with ES= 0,88 (95% IC 0,58-1,18) versus ES= 0,85 (95%IC 0,57-1,17) for EQ5-D. Conclusions Results suggest that EHP-5 and EQ-5D have equivalent responsiveness to change but EHP-5 is more sensitive to the endometriosis? characteristics. It should be a valuable specific tool for French-speaking patients with endometriosis, both for daily practice and studies evaluating the impact of surgical interventions ------------------------------------Mots clefs : Endometriosis, pelvic pain, quality of life questionnaires, psychometric validation, responsiveness to change Auteurs : Références : , , , Auteurs Gabrielle AUBRY 1, Marion RAVIT 2, Guillemette THOLLIER 3, Cyrille HUCHON 4, Pierre PANEL 5, Arnaud FAUCONNIER 4, 1. Gynaecology and Obstetrics, CHU Strasbourg, Strasbourg, FRANCE 2. ) Research unit EA 7285 RISCQ, University of Versailles-Saint Quentin, Montigny, FRANCE 3. Research Unit, CH Versailles, Versailles, FRANCE 4. Gynaecology and Obstetrics, CHI Poissy, Poissy, FRANCE 5. Gynaecology and Obstetrics, CH Mignot, Versailles, FRANCE Auteurs (raw format) AUBRY Gabrielle - email : [email protected] Etablissement : CHU Strasbourg Service : Gynaecology and Obstetrics Ville : Strasbourg Pays : FRANCE Présentateur : Oui RAVIT Marion - email : [email protected] Etablissement : University of Versailles-Saint Quentin Service : ) Research unit EA 7285 RISCQ Ville : Montigny Pays : FRANCE Présentateur : Non THOLLIER Guillemette - email : [email protected] Etablissement : CH Versailles Service : Research Unit Ville : Versailles Pays : FRANCE Présentateur : Non HUCHON Cyrille - email : [email protected] Etablissement : CHI Poissy Service : Gynaecology and Obstetrics Ville : Poissy Pays : FRANCE Présentateur : Non PANEL Pierre - email : [email protected] Etablissement : CH Mignot Service : Gynaecology and Obstetrics Ville : Versailles Pays : FRANCE Présentateur : Non FAUCONNIER Arnaud - email : [email protected] Etablissement : CHI Poissy Service : Gynaecology and Obstetrics Ville : Poissy Pays : FRANCE Présentateur : Non