nologie

tssN 0998-2000
Bulletin
d 'lnformation
de la Société
F
ie
nologie
d
No 60 - Octobre 1991
Pri r:6 F -T ri me stri e l
Sommaire
1
Londres
2
3èmeCoursSFI.................
........ 3
AtelierTechnologique
3
BourseCassenne
Congrès,colloques
CoLtrs,Workshops
Annonces
x.....
Hypoth
èses,éditoriau
3/4
4
4
4/6
LE POINTSUR LONDRES
troisvolets:
Le Programme
définitifde la réunioncommuneBSI/SFIvientde nousparvenir.ll comporte
R. Rees,D.
M. Fougereau,
on theimmunerepertoire-G.Janeway,
Mardi 15 octobre: Mainsymposium
Wiley,L. Moretta,C. Benoistet C. Millstein.
Mercredi 16 octobre: I colloquia
processing
5) lmmunedeficiencies
and presentation
1)Antigen
receptors
6) lmmunoglobulin
and tolerance
2) Autoimmunity
7) Mucosalimmunity
3) Cytokines
andadhesion
8) Signalling
4) lg andTCRgenesandstructure
:
Jeudi 17 octobre: 5 Workshops
Societyandthe BSI
lmmunology
Groupof the Biochemical
1) Fc receptors
organised
by the Biochemical
lmmunology
organised
by the materno-fetal
Eventsfor fetalgraftsurrvival,
2) Speciallmmunological
lmmunology
Veterinary
Group.
Groupand the Comparative
group.
in lnfectionof the NervousSystem,organisedby the Neuroimmunology
3) lmmuneResponses
Societyand the SFl.
organised
by the RoyalMicroscopical
4) Cell Function:a cytometric
approach,
BSI
and
the SFl.
members
of
the
in
Arthritides,
organised
by
lmmunity
the
Gollagen
5)
3ème COURS ANNUEL DE LA SFI sous l'égidede la FondationMarcel
Mérieur, Centre des Pensières.
P ROG RA MMEDE F I NI T I F
LUNDI 18 NOVEMBRE
Matin
Après-midi
14.00-15.00
15.00-16.00
16 .00 - 1 6 .30
16.30-17.30
17.30-18.30
Arrivéedesparticipants
T: MarcBONNEVILLE
Récepteur
deslymphocytes
à I'antigène
B:
AntonioFREITAS
des
cellules
et cinétique
Ontogénèse
P ause
T et sélection
du répertoire
de reconnaisance:
Ontogénèse
deslymphocytes
MaTcBONNEVILLE
B (l):A. FREITAS
et sélection
desrépertoires
deslymphocytes
Cinétique
MARDI 19 NOVEMBRE
Matin
9.00-10.00
10.00-11
.00
.3 0
11.0 0 - 1 1
11.30-12.30
Après-midi
15.00-16.00
16.00-17.00
17.00-17.30
17.30-18.30
Soir
20.30-22.30
B (ll):AntonioFREITAS
desrépertoires
deslymphocytes
Cinétique
et sélection
T /ô : MarcBONNEVILLE
Lymphocytes
P ause
immédiate:
AlainDEWECK
Réactions
d'hypersensibilité
Dominique
CHARRON
Biosythèse
du CMH,ontogénie:
desprotéines
AlainDEWECK
et manifestations
allergiques:
Cytokines
Pause
AlainDEWECK
Auto-anticorps
antilgEdansl'allergie:
leucocytaire:
AlainBERNARD
Lesclassesde différenciation
MERCREDI 20
Matin
9.00-10.00
10.00-11.00
11.00 - 1 1
.30
11.30-12.30
12.30-13.30
Après-m'rrCi
Mdin
9.00-10.00
10.00-11.00
11.00-11.30
11.30-12.30
Après-midi
15.00-16.00
16.00-17.00
1 7 .00 - 1 7 .30
17.30-i8.30
Soir
20.30-22.30
CHARRON
Régulation
de I'expression
desgènesdu CMH(l):Dominique
T et latolérance:
ClaudeCARNAUD
Rôledu CMHdansla miseenplacedu répertoire
P ause
CHARRON
Régulation
desgènesdu CMH(ll):Dominique
de I'expression
(l):Claude
Autoimmunité
CARNAUD
Libre
JEUDI 21
(l):Thierry
DEFRANCE
Lymphokines
et leursrécepteurs
(l):Philippe
Adhésion
NAQUET
cellulaire
Pause
(ll):ThierryNAQUET
Lymphokines
et leursrécepteurs
Autoimmunité(ll):ClaudeCARNAUD
ThierryDEFRANCE
Lescentresgerminatifs:
P ause
Activation
B : Jean-François
DELFRAISSY
deslymphocytes
Forum
VENDREDI22
Math
9.00-10.00
10.00-11.00
1 1 .00 - 1 1 .30
11.30-12.30
12.30-13.30
le systèmeimmunitaire
DELFRAISSY
Virusaffectant
- HIV:Jean-Frarçois
(ll):Philippe
Adhésion
NAQUET
cellulaire
P ause
le systèmeimmunitaire
DELFRAISSY
Virusaffectant
- EBV:Jean-François
Activationcellulaire:PhilippeNAQUET
AP r ès - m idi
D é Pa d
rrrrrrrrrrrr
Lesorganisateurs
signalentqu'ilresteencorequelquesplacespour le Coursdes Pensières(Annecy).Les
horairesont été repenséspourqu'ily ait plusde tempspourlesdiscussions
et lescontactsaveclesconférenciers,
du "tempsde
auxCoursprécédents.
Cetteamélioration
ce quiavaitété le souhaitexprimépar lesparticipants
devront
travail"devraitdoncfav'oriserles échangescar le prcgrammeesttoujourstrèsdense.Les retardataires
!
demanderleurinscriotion
d'urqence
ATELIERTECHNOLOGIQUE
BEHRING.SFI
CONGRES,COLLOOUES
1991
15-17oct - REUNIONCOMMUNEBSI/SFI,
BARBICANCENTRE,LONDRES.
Le 1Oème
AtelierTechnologique
auralieule samedl
8 NOv- SCLEROSE
EN PLAQUES,
Ac{ua|ités
en
14 décembre1991,au Département
des
Génétique,
Neuropsychologie
lmmunobgie,
et
Jardin
Enseignements
de l'lnstitutPasteur.Organisépar
du Pharo,Marseille.'Bulletins
d'inscription:
ARSEP,4
Jean-LucGuesdon,avecI'aidede Danièle
rue
Chéreau,
75013
Paris.
Tél:45
65
00
36.
Chevrler et Véronlque Stonnet,cet Atelierportera
suTIesMETHODESDE MARQUAGEET DE
1992
DETECTIONNON.RADIOACTIVES
DES
15-21 ian - Keystone
MOLECULAR
Symposia:
AND
AC I D ESN U C LEIQUE S .
CELLUI.AR
B]OLOGYOF HOST/PARASITE
L'objectif
de cet Atelierestde discuterde I'intérêt,
des
INTERAOTIONS,
ParkCity,Utah.*POB2156,Dillon,
avanlageset des limitesdesdifférentes
méthodes
de
co 80435,USA.
marquage
non-radioactif
des acidesnucléiques.
19-26 jan - KeystoneSymposia:
BONEMARROW
L'Ateliercomportera
d'unepart,des exposéssur les
TRANSPLANTATION,
Keystone.'POB
2156,Dillon,
principes
des méthodeset leursapplications;
et d'autre
co 80435,USA.
part,destravauxpratiques.
10.14 Iév - lSTIUISAFRICAN
IMMUNOLOGY
Lesapprochessuivantesserontdiscutéeset étudiées MEETING,
Harare.'Abstracts:
DrA. Esa,Deptof
en travaux pratlques:
lmmunology
and InfecliousDiseases,
TheJohns
- Modification
chimiquedes acidesnucléiques
et des
Hopkins
SchoolofPublicHealth,615N. WotfeSt,
pardes marqueurs
oligonucléotides
macrornoléculairesBaltimore,
MD21205.*Registration:
Dr H. Cadman,
ou pardes rnolécules
de faiblepoidsnnléculaire.
Deptof Biochemistry,
Univof Zimbawe,POB167,
- Modification
enzymatiquein vitrodesADN
Avondale,Harare,Zimbawe.
(Multipriming,
PCR).
14-16 fév - 4th IntematConfon LYMPHOCYTE
- Hybridation
surdifférentssupports.
ACTIVATION
ANDIMMUNEREGUI-ATION.
Theme:
- Détection
des hybridesADN/ADNou ADN/ARNpar
.Divisionof BasicandClinical
CellularCommunications.
bioluminescence,
fluorescence
ou colorimétrie.
lmmu.rrclogy,
MedSc l. c2M-A,Univof California,
lrvine,
cA 92717,USA.
Le nombredes participants
seralimitéà 30.Les
5-11 mar - Keystone
Synp:ANTIGEN
peuventencoredemanderune
redataires
intéressés
PRESENTATION,
FUNCTIONS
OFTHEMHC,Taos,
fiched'inscription
au secrétariat
de la SFI(4563 Bl 64
NewMexico.'POB2156,Dillon,CO 80435,USA.
ou 45 66 85 97).
Ce 1OèmeAtelierTechnologique,
commeles
24.26 mar .2nd EUROPEAN
YOUNGSCIENTISTS'
précédents,
par les Laboratoires
est sponsorisé
CONFERENCE
ON IMMUNOLOGY,
Czechostovakia.
Behring,
ce quipermetà la SFlde rembourser
lesfrais
'2nd EYSC92,clo CADCongressAgency,Trade
de déplacement
et de séjourdesparticipants
surles
Csntrum,Wonkova1142,50002HradecKralové,
basessuivantes:
Czechoslovakia.
- Voyage:train,2èmeclasse(réduction
Congrès).
24-27 mar - SGMMeetingNo122,Univof WanrkJ<.
'Dr
- Hôtel:forfait250F(surprésentation
desjustificatifs). C.S.A.Dow,Deptof BiologicalSc,
Univof Wanrick,
CoventryCV43AL.
26-27 mar - BSRSpringMeeting,Southampton.
Tel:
071 2243739.
1-3 avr - BSISpringMeeting,UnivSheffietd.
3
symposia:
AntibodyStructureand Function/ Tumour
lmmunology
andMoleolar Pathology
/ Regulation
of
BOURSECASSENNE/SFI
Cytokines.'BSlOffice,
2 TdangleHouse,2 Broomhill
Road,LondonSWl8 4HX.
9.10 avT. REUNIONDE PRINTEMPS
DE LA
Quatozedossiersde candidature
parvenus
SFl, Ecole Normale Supérleure de LyON.
sont
à la
S.F.l. Le Jury,présidépar le Président
de taS.F.t.a
13-15avr - 3ld INTERNAT
CONFONSLE,London.
attribuéla bourse,d'unmontantde 100000 F. à
'Dr G.R.V.Hughes,LupusLab,the Raynelnst,St
Véronique
qui,aprèssontravaitde
THOMAS-VASLIN
Thomas'Hosp.,
LondonSEl 7EH.
thèseréalisédansle laboratoire
du PrA. Coutinhoà
13.15 avT - VACCINES
FORENTERIC
DISEASES,
l'lnstitutPasteur,ferasonstagepost-doc{oraldans
le
Cambridge,
UK.'Buttenvorth
Heinemann
Ltd.,Linacre
laboratoire
du Pr N. Le Douarinà l'lnstitut
d'Embryologie
House,
Hill,
Jordan
Oxlord
OX2
8DP.
du CNRSet du Collègede France,à Nogentsur Mame.
29 avr-3 mal - lst IntematCongress
on
TRANSPI-ANTATION
IN DEVELOPING
COUNTRIES,
Singapore.'Secretariat,
NationalKidneyFoundation,
705SerangoonRd,Singapore1232,lndia.
3
2-6 mal - 4th InternatTNFCongress,
Eindhoven.
medicaldoclors
withteachingcommitments
in their
'Secretariat,
Deptof Surgery,University
of Limburg,
country.ApplybeforeJanuary1Sth.Programme
and
BMC,POB616,6200MDMaastricht,
TheNetherlands. Generalinformation
18,20133
- ESO,ViaVenezian
Milan,ltaly.TeI: 39H7 0635923.Fax:39lU26æ662.
13-15 mal - 8th InternSympof lmmuno/Rhumatology,
*J.
Montpellier. Sany/J.Clot,lmmuno-Rhumato.,
Centre 12-14mar -The SKIN IMMUNESYSTEM,Royal
GuideChauliac,
34059Montpellier
Cedex.
LondonHospital.'Dr lreneLeigh,Dptof Experimental
Dermatology,
LondonHospitalMedicalCollege,56
8-12 juln - Internat
AND
Confon CELLULAR
Ashfield
St,
London
El 2BL.TEL:071377 7724.
MOLECULAR
ASPECTSOF SELF-REACTIVITY
AND
AUTOIMM
UNE DISEASES,
Taormina.
Abstracts
6-10 avr - NATOadvarrced
StudyInstitutes:
NEW
March1st.'Secretariat,
deadline:
DEVELOPMENTSIN FLOW CYTOMETRY.The
CentroStudi
Congressi,
ViaTimeo1, 98039Taormina(ME),ltaly.
courseconsistsof a corecurriculum,data management
Tel:0942123836.
expertsystemsandcellsortingtechniques.
Three
options:
Cell
activation
biological
response
ard
rnodif
ier
juln
21-25
- 2ndIntematSympon DENDRITIC
CELLS
Membrane-ligand
/
interactions
identity
and
cell
/
IN FUNDAMENTAL
AI{DCLINICAL
IMMUNOLOGY,
* BureauPAOGAmsterdam,
Nuclearcomponents
formard function.Deadline:Oct
Noordwijkerhout.
*MmeD.Laird,
28,91.
CNRS,CTSRC-UPS47,
Lab
Talelbergweg
25, 1105BCAmsterdam,
The
Cytométrie,
BP
Villejuil
3,
94801
Tél:46
Cedex.
78 66
Netherlands.
0 7 . F a x 4 72 6 0 4 7 5 .
1&20 août - 7th lnternatCongress
of MUCOSAL
Courseon
IMMUNOLOGY,
Prague.* Drs.J. StezUH.Tlaskalova, 30 août-3 sept - EFIS:JohnHumphrey
*Dr Eugen
TUMOUR
IMMUNOLOGY,
(Romania).
lasi
Czechoslovak
Academyof Sciences,Instof
Carasevici,
Clinicade Orrcologie,
Laboratorul
de
Microbiology,
Videnska1083,14220Prague4 - Krc,
lmurrclogie
Tumorala,
Spitalul
Universitar
St
Spiridon,
Czechoslovakia.
b-dulIndependentei
1, 6600lasi,Romania.
23-28 aoÛt -8th Internat Congress of
Applications
deadline:
April15.
lmmunology,Budapest.
Abstracts
deadline:
31
13-20 sept - JohnHumphrey
AdvancedSummer
January..c/o IPv/lntercongress,
h-1068,Budapest,
School
in IMMUNOPATHOLOGY:
Spotlight
on
DozsaGy.ut 84/a,Hungary.
Autoimmunity,
Tashkent.
'Dr G.L.Asherson,
Clinical
31 août-2 sept - lgANEPHROPATHY'THE
25TH
Research
Centre,WatfordRoad,Hanow,HA1,3UJ.
YEAR",InternatSymp,Nancy.Themes:1) Historical
Background;
2) Clinicalfeaturesandlongterm
outcome;3)
Themesangium;4)
Peripheral
bloodcells;
5) Solublelactors;6)Genetics;7) Mucosae;
8) Models;
ON NOUSPRIE D'ANNONCER....
' Lab lmmunologie,
9) Therapeutics.
BP 184,Av de la
Forêtde Haye,54500Vandoeuvre-les-Nancy.
Tél:83
5 9 2 8 56 .Fax:834 46022.
- Le décèsde notrecollègue,JacquelinePANOUSE,
22-23 sept - REUNIOND'AUTOMNE
DE LA
Prolesseur
éméritede la Facultéde Médecineet de
SFI, FACULTEDE MEDECINEDES SAINTS
Pharmacie
de Besançon,
survenule 13 septembre
PER ES,PAR IS.
1991.
COURS,WORKSHOPS
- L'attribution
du prixde la LigueNationaleFrançaise
Contrele Cancerau Dr SalemChouaibpoursestravaux
surlescytokines
et I'immunité
antitunrorale.
1991
18-22noy -3ème COURSANNUELde la SFt,
sousl'égidede la Fondation
MarcelMérieux,Annecy.
'secrétariatde la sFl (4568 81 64/4566 85 97).
14 déc -1OèmeAteller Technologlque
Behrlng/SFl, lnstitut
Pasteur.
METHODESDE
MARQUAGEET DE DETECTION NON.
RADIOACTIVESDES ACIDES NUCLEIQUES.
Organisateur:
Jean-Luc
Guesdon.'SFl.
1 992
European School of Oncology:
ESO courses areresidential,
fullimmersion
educationaladivitiesfor postgraduates
of various
disciplines
whowishto leamaboutthefundamental
aspectsof oncologyor to updatetheirknowledge
in the
field.Courses(in English)areheldin OrtaSanGiulio.
40 Fellowships
are availablefor ECand Swedish
EDITORIAUX
OLOCALIMMUNITY
ANDTHEUTERINE
CERVIXIMPLICATIONS
FORCAI.ICER-ASSOCIATED
VIRUSES.
J.K.Roche,C.P.Crum.Cancerlmmurclogy
Immunotherapy, 33,4,203.
0 Review:CYTOKINES
lN T CELLDEVELOPMENT.
S.R.Carding,A.C.Hayday,K. Bottomly.Immunology
Today,12,7,239.
0 Editorial:
IMMUNOASSAYAUTOMATION.
R.GNg. J
of Clinicallmmurnassay,| 4,2,59.
0 Overview:
CELLSMEDIATING
ALLOGRAFT
REJECTION.
B.M.Hall.Transplantation,
51,6,t141.
OTheNETWORK
THEORYOFAUTOIMMUNITY
IN
L.A.Lee.J of lnvestigative
BULLOUSPEMPHIGOID.
Detmatology,96,6,80| .
OF
REGULATOR
OIL 6 - A MULTIFUNCTIONAL
J
W. Pzul.Japanese
ANDINFLAMMATION.
IMMUNITY
of CancerResearch,82,6,UR|.
0 Proc ot the Socfor ExperimentalBiologyand
Medicine,197,3. Minireviews:
./ eONe andthe IMMUNESYSTEM.H.E.Gruber.P.2l9
H. lkematsu,
M.T.Kasaian,
r/cos+ LYMPHOCYTES-B.
P.Casali.P.226.
R.w.
./ RecEproRS THATAcrlvATE PLATELETS.
Cofman.P.242.
ION
OF INTESTINAL
{ IuuUruCSYSTEMCONTROL
P.249.
Powell.
D.W.
Hinterleitner,
T.A.
TRANSPORT.
BETWEEN
0 Review:TheINTERACTION
PROTEIN
C4b.BINDING
COMPONENT
COMPLEMENT
FORMS
PROTEIN.S
ANdtheVITAMIN-K-DEPENDENT
the
and
BLOOD
COAGULATION
a LINKBETWEEN
Biochemical
M.
Hessing.
SYSTEM.
COMPLEMENT
277,111,581.
Journal,
OF
REGULATION
TRANSCRIPTIONAL
0 Review:
W|IIIAMS.
B.R.G.
GENES.
INTERFERON.STIMULATED
200,1,1.
EuropeanJ of Biochemistry,
and
0 MilsteinAwardLecture:INTERFERON-INDUCED
ENZYMES- A
RNA-ACTIVATED
DOUBLE-STRANDED
AND2',5'-OLIGOKINASE
PROTE|n
SPECIFIC
J of
A.G.Hovanessian.
SYNTHETASES.
ADENYLATE
hterteronResearch,11,4,199.
THERAPYof
ANTI-RETROVIRAL
0 Perspective:
VIRUSINFECTION
HUMANIMMUNODEFICIENCY
IOTthE
ANdCHALLENGES
STRATEGIES
CURRENT
R.Yarchoan,
J.M.Pluda,C.F.Perno,H.
FUTURE.
Mitsuya,S. Broder.Blood,78,4,859.
IMMUNOGLOBULINS.
INTRAVENOUS
OEditoriA|:
A.D.B.Webster.BritishMedicalJ, 303,6799,375.
ANd
MACROPHAGE
ALVEOLAR
OEditoriAl:ThE
JOf
J.N.FiNK.
PNEUMONITIS.
HYPERSENSITIVITY
Lafuratoryand ClinicalMedicine,117,6,435.
ANTI-IDIOTYPIC
ThEPHYSIOLOGYOf
OReview:
INTERACTIONS
- FROMCLONALtOPARATOPIC
aN
ON.J.M.Greally.Clinicallmmunology
SELECTf
60,1,| .
Immunopathology,
0 Nature,351,6326. News& Views:
M.J.
of a srAR PERFoRMER.
{ ecc - REBTRTH
Colston.P.442.
M.s.co,
{ HurueruzËoRNïeoDlES FoR THERAPY.
.
C . Qu e e nP.501.
- BETWEENB-CELLS
ONews& ViEwS:IMMUNOLOGY
andT-CELLS.A.L.Defranco.Nature,351,æ28,603.
review:HUMANLYMPHOCYTES-B
0 Editorial
MATURE.J. Gordon.ClinicalandExperimental
lmmunology,84,3,373.
THERAPY
OfHUMAN
ANTIBODY
OMONOCLONAL,
tO
CANCER- TAKINGthEHER2PROTOONCOGENE
G.D.Lewis,J.C.Sarup,B.M.
theCLlNlC.H.M.Shepard,
l. Figari,C.E.Kotts,
J. Mordenti,
Fendly,D. Maneval,
A. Ullrichelal. J of Clinballmrntrnbgy,
M.A.Palladino,
1 1,3,11 7 .
CELLS
OfEFFECTOR
OReview:ThEPREPARATION
for USEin thEADOPTIVECELLUI.AR
OfHUMANCANCER.J.R. YANNEII|.
IMMUNOTHERAPY
J of lmmunologiælMethods,139,1,1.
0 Review:IMMUNOPARASITOLOG]CAL
-A
in SCHISTOSOMIASIS
PARAMETERS
VIEWOfA VACCINE.ORIENTED
PERSPECTIVE
R. Arnon.Vaccine,9,6,379.
IMMUNOCHEMIST.
CELLULAR
TARGETED
0 Review-Comment:
ANTIBODIES.
IMMUNOTHERAPYWithBIFUNCTIONAL
H. Nelson.CancerCells,3,5,163.
-A
BIOLOGY
of AUTOIMMUNITY
Lecture:
0 P. Rambotti
aN Exprimental
REVIEW.C.L.Christian.Clin'rcal
9,3,213.
Rheumatology,
Letters:BLOODTO BRAIN
0 Pharmacology
LINKSthe ]MMUNE
of INTERLEUKIN
TRANSPORT
SYSTEMS
andCENTRALNERVOUS
W.A.BANKS,
COMMUNICATIONS.
ACCELERATED
| 7.
A.J.Kastin.Life Sciences,48,25,PL1
for
BLOODTRANSFUSION
EXCHANGE
0 Editorial:
INFECTION
FALCIPARUM
PLASMODIUM
SEVERE
or STILLSUBin MANAGEMENT
ADJUNCT
PROVEN
G.C.Cook. J of lnfection,22,3,213.
JUDICE.
ACTIVATION
IMMUNE
INTERLEUKIN-I,
0 Review:
iN
MECHANISMS
PATHWAYS,
ANdDIFFERENT
B.
ARTHRITIS.
ANdRHEUMATOID
OSTEOARTHRITIS
Annalsof the RheumaticDiseases,50,6,395.
Kirkham.
Allergy,21,3May 1991.
0 Clinicaland Experimental
Reviews:
{ truHeleoDRUGSandthe LUNG.Q.A.Summers.P.
259.
./TNEHIGHAFFINITY
IOTIgEONMAST
RECEPTOR
CELLS.H. Metzger.P.269.
andT-CELL
0 ANALYSIS
of IMMUNOGLOBULIN
GENES:
RECEPTORS
P. /
1) BasicandTechnicalAspects.
and
in the Diagnosis
andLimitations
2) Possibilities
Diseasesand
Management
of Lymphoprolilerative
P. 93.
RelatedDisorders.
ClinicaChimicaActa, 198,1-2,April 1991.
LYMPHOCYTE-T-STIMULATING
0 Minireview:
B.
TOXINS
ASSUPERANTIGENS.
MICROBIAL
Fleischer.MedicalMicrobiologyaN lmmunology,
190,2,53.
or
CAMEFIRST,MHCCLASS-1
0 Hypothesis:WHICH
M.
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