J LSD No. 566 J _102al M 500 effect of LSD and

J
LSD No.
566 J _102al
M 500
effect
agents
fish
WEISS,
f
B., ABRAMSON,
H.A.,
BARON,
li.O.
of LSD and other
on Siamese fighting
Wirkung verschiedener Pharmeka beim si_nesischen
Kampffisch
WEISS, B., _0N,
H.A., BARON, %1.0. (Biol.Lab., Cold
Spring
Harbor,
New York)
Lyser_ic acid dieth_lamide ([ZI_25). XXV. Effect of po%assi"m
cyanide and o%her oxidase and resplra%o_ inh/bi%ors on %he
Siamese fi_htin_ fish.
(Lysergs_ured/KthYlamid (LSD 25). XXV. Wirkung yon Kaliumcyam/d und anderen oxydase- und a%munEsh_-.enden Substanzen
auf den siamesischen Kampffisc/1).
Arch.Neurol.Psychiatr.,
ChicaEo
Kaliumc_anid
hatte
beim siamesischen
LSD-artige
Wirkung. Diese
war reversibel,
holte
sich rascher
als nach LSD.
80,
345-350 (1958).
Kampffisch
und der Fisch
eine
er-
Natriumazid wirk%e Khnlich wie LSD.
Hydrazinsulfat und salzsaures HydroA-/lamin waren wir-
k._slos.
Anoxie und Asphyxie riefen die f[irdie LSD-Wirkung
charak%erls%ische Stellung hervor (Schnauze aufwKrts,
Schwanz abw_rts gerichtet).
Farbstoffe wie Methylenblau, Bindschedler-_riin,
Natrium-2,6-dichlorbenzol-indophenol, _entianaviolett ,nd
Methylvlolett bewirkten ebenfalls ein dera_-tiges Verhalten
des Fisches, anzunehmenderweise als Anoxiefolge.
D
115n/20
*VI LSD No. 566 _ _102a_
M 500 effect of LSD and other
agents on Siamese fighting
fish
WEISS,
BARON,
B., ABRAMSON,
H.A.,
w3 (EK 13'567)
_/_.B_/_.Spi/pz
io_
_!.0.
Effect of various agents on the Siamese fighting fish
WEISS, B., ABRAMSON, H.A., BARON, M.0.
Spring Harbor, New York)
(Biol.Lab.,Cold
Lyser_ic acid die th_lamide (LSD-2_). XXV. Effect of pota:_sium
cyanide and other oxidase and ;espiratorYinhib!tors
on the
Siamese
fi_htin_
fish.
Arch.Neurol.Psychiatr.,
•
Chicago 8__0,
345-350 (1958)
Potassium cyanide had an LSD-like effect on Siamese
fighting fish. The effect was reversible, the fish recovE_ring
more rapidly than after LSD.
Sodium azide had an effect similar to that of LSD.
Hydrazine sulphate and h_droxylamine h_drochlQride had
noeffect.
Anoxia aid asphyxia produced the nose-up, tail-down
position characteristic
of LSD. The effect was reversible.
Dyestuffs such as methylene blue, Bindschedler's green,
sodium-2,6-dichlorobenzene indophenol, gentian violet and
methyl violet produced similar phenomenA, which are believed
to be connected with anoxia.
115n/2o
_ •
*VI LSD No. 566 [§102a]
"_' _ISS,
-3 (_
M 500 effect of LSD and other
agents on Siamese fighting
fish
B., ABRAMSON, H.A., BARON, M.0.
_5,567)
Effet de divers agents sur le poisson combattant slam,is
.
WEISS, B., ABRA_0N, i_.A.,BARON, M.0. (Biol.Lab. Cold
Spring
_orbor,
NewYork)
'
'_
Lyser_ic acid diethyl_m_de (LBD-2_). XXV. Effect of potassium
cyanide and other oxidase and respiratory _nh_bltors on the
Siamese fighting fish.
(D±4thy]_m_dede l'acide lysergique (LSD 25 ). XXV. Effet
sur le poisson combattant siamois de cyanure de potassi_zn
et d'autres substances inhibant l'oxydase et la respira;ion)._
Arch.Neurol.Psychiatr.,
0hicago 80, 345-350 (19!i8).
Cyanure de potassium exerce sur le _oisson combatta:it
siamois un effet ressemblant h celui de ISD. Cet effet est
r4versible et le poisson se r4tablit rapidement apr&s L!;D.
Azide de sodium exerce un effet s4milaire h celui d_ L_D.
•
Sulfate d'_ydrazine et _ydrochlorured'_¥droxyl_u_
restent sans effet.
e
J
Anoxie et asph.yxieprovoquent l'a_titude caract4ristique
pour l'effet du LSD (museau dirig6 vers an haut, queue dirig_e
vers
enbas).
!
Des colorants tel le bleu de m4thyl_ne, le vert de
Bindschedler, le sel sodique de 2,6-dichlorobenzol-indo_h_nol,
le violet de gentiane et le violet de m_thyl provoquent des
ph6nom&nes similaires que les auteurs mettent en rapport
avec l'anoxie.
-!
c
F
n5 zz/2o
I