education research experience publications

Guillaume SESCOUSSE, PhD
Donders Institute for Brain, Cognition and Behaviour
Donders Centre for Cognitive Neuroimaging
PO Box 9101, 6500 HB Nijmegen, The Netherlands
E-mail: [email protected]
Tel: +31 (0)24 36 10618
EDUCATION
2006-2010
PhD in cognitive neuroscience – Centre de Neuroscience Cognitive, Lyon, France
2005-2006
MSc in cognitive neuroscience – Centre de Neuroscience Cognitive, Lyon, France
Sep-Dec 2004
Exchange semester in psychology – Concordia University, Montreal, Canada
2002-2005
BSc in Biochemical Engineering at the Institut National des Sciences Appliquées
(INSA: Grande Ecole), Lyon, France
2000-2002
Preparatory School at INSA, International program "EURINSA", Lyon, France
June 2000
Baccalauréat Scientifique (with distinction), majoring in Math, Physics and Biology,
International High School of Lyon, France
RESEARCH EXPERIENCE
2011-
Donders Centre for Cognitive Neuroscience, Nijmegen, Netherlands
Postdoctoral fellow
Project: The role of dopamine in healthy and pathological gambling
Advisor: Roshan Cools
2006-2010
Centre de Neuroscience Cognitive, CNRS, Lyon, France
Phd student
Thesis: Neural correlates of reward processing and decision-making in
healthy individuals and psychiatric patients
Advisor: Jean-Claude Dreher
2005-2006
Centre de Neuroscience Cognitive, CNRS, Lyon, France
Master’s student
Thesis: Processing of primary and secondary rewards in the brain
Advisor: Jean-Claude Dreher
Feb-July 2005
Montreal Neurological Institute, McGill University, Montreal, Canada
Trainee
Project: Neural correlates of gambling in healthy and pathological gamblers
Advisor: Alain Dagher
July-Aug 2003
Institut cellule souche et cerveau, INSERM, Lyon, France
Trainee
Project: The effect of twilights on rodents’ behavior
Advisor: Howard Cooper
PUBLICATIONS
Manuscripts accepted or under revision
Sescousse G., Redouté J. & Dreher J-C (2010). The architecture of reward value coding in the
orbitofrontal cortex. J Neurosci 30:13095-13104
Ligneul R.*, Sescousse G.*, Barbalat G., Domenech P. & Dreher JC (2012). Shifted risk
preferences in pathological gambling. Psychol Med [Epub ahead of print] [* equal contribution]
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Sescousse G., Barbalat G., Domenech P. & Dreher J-C. Imbalance in the sensitivity to different
types of rewards in pathological gambling (under revision)
Sescousse G., Caldù X., Segura B. & Dreher J-C. Processing of primary and secondary rewards: a
quantitative meta-analysis and review of human functional neuroimaging studies (under revision)
Manuscripts in preparation
Sescousse G., Li Y. & Dreher J-C. The role of the ventral striatum in the relative motivation for
monetary and erotic rewards
Sescousse G., Eche J., Saoud M., d’Amato T. & Dreher J-C. Preserved processing of primary and
secondary rewards in medicated patients with schizophrenia
Li Y.*, Sescousse G.* & Dreher J-C. Reward anticipation-related signals in the orbitofrontal cortex
and striatum positively correlate with reward incentive-induced changes in testosterone levels in
men [* equal contribution]
Sescousse G., Rogues S., Versini A., Ramoz N., Gorwood P. & Dreher J-C. Risky decision-making
in anorexic patients reveals reversed loss aversion for food
Sescousse G., Domenech P., Barbalat G., Wydoodt P., Metereau E. & Dreher J-C. Brain
mechanisms underlying the gambler’s fallacy bias in healthy and pathological gamblers
Book chapter
Sescousse G., Bault N. & Chambon V. (2011). Chocolat, sexe et argent: Comment le cerveau
représente-t-il les récompenses? [Chocolate, sex and money: how does the brain represent
rewards?]. In "Peut-on se passer des représentations en sciences cognitives?" (ed. J-M Roy),
De Boeck, Bruxelles
CONFERENCE PRESENTATIONS
Oral presentations
June 2010
Exacerbated response to monetary rewards… or disturbed response to nonmonetary rewards in pathological gamblers? 16th annual Meeting of the
Organization for Human Brain Mapping, Barcelona, Spain
June 2007
The representation of rewards in the brain: the examples of sex and money.
National meeting of the young investigators in cognitive science, Lyon, France
Poster presentations
June 2012
Li Y., Sescousse G. & Dreher J-C. Correlation between testosterone levels
and reward-induced activity in orbitofrontal cortex in men. 18th annual
Meeting of the Organization for Human Brain Mapping, Beijing, China
January 2012
Ligneul R., Sescousse G. & Dreher J-C. Pathological Gambling assessed with
Prospect Theory. 7th Alpine Brain Imaging Meeting, Champéry, Switzerland
June 2010
Sescousse G., Barbalat G., Domenech P. & Dreher J-C. Exacerbated
responses specific to monetary rewards in pathological gamblers. 16th annual
Meeting of the Organization for Human Brain Mapping, Barcelona, Spain
June 2009
Sescousse G., Eche J., Saoud M., d’Amato T. & Dreher J-C. Processing of
primary and secondary rewards in patients with schizophrenia. 15th annual
Meeting of the Organization for Human Brain Mapping, San Francisco, US
October 2008
Sescousse G. & Dreher J-C. Coding of reward type along an antero-posterior
gradient in the human orbitofrontal cortex. Biology of Cognition meeting
(Exciting Biologies series), Chantilly, France
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June 2007
Sescousse G., Redouté J. & Dreher J-C. Comparing brain networks involved
in the processing of monetary and visually erotic rewards. 13th annual Meeting
of the Organization for Human Brain Mapping, Chicago, US
June 2006
Sescousse G., Aw A., Aulakh H., Farago P., Gupta R., Derevensky J. &
Dagher A. The effect of anticipation and receipt of monetary reward on brain
activation of normal controls during a gambling task: an fMRI study. 12th
annual Meeting of the Organization for Human Brain Mapping, Florence, Italy
INVITED TALKS
March 2013
Investigating the links between dopamine and gambling using pharmaco-fMRI
in humans. Workshop on translational research on poor decision-making and
the sensation-seeking supertrait in humans and animal models, Rome, Italy
June 2012
Imagerie cérébrale dans le jeu pathologique. 110e Congrès de Psychiatrie et
de Neurologie de Langue Française, Montpellier, France
July 2011
Récompense et décision: Un nouvel éclairage sur la psychopathologie des
conduites addictives. Centre de Psychiatrie et Neuroscience, INSERM U894,
Paris, France
January 2010
Characterisation of loss aversion behavior in anorexia nervosa. 7th Regional
meeting on eating disorders, Lyon, France
March 2007
Cerebral imaging of male sexual motivation. Brain awareness week, Lyon,
France
AWARDS | FELLOWSHIPS | GRANTS
2011-2012
NWO Rubicon Postdoctoral Fellowship (2 years)
June 2010
HBM Trainee Abstract Award
Jan-Dec 2010
French Medical Research Foundation (FRM) fellowship (1 year)
2008-2010
Grant from the French National Agency for Drug and Addiction Control (MILDT)
(46 000 €)
October 2008
Conference travel grant, University of Lyon neuroscience graduate program
August 2007
UCLA Advanced Neuroimaging Summer Training Program fellowship
2006-2009
French Research Ministry PhD fellowship (3 years)
2005-2006
French Education Ministry MSc fellowship (1 year)
TRAINING
April 2012
IVO Master Class Addiction 2012, The Hague, Netherlands
June 2009
Introduction to imaging genetics, Educational course offered by the Organization
for Human Brain Mapping, San Francisco, US
August 2007
UCLA Advanced Neuroimaging Summer Training Program, Los Angeles, US
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TEACHING / SUPERVISION
Courses
January 2012
Nutritional Neuroscience: the computation of food value in the brain, Nutrition
and Health Bachelor Program, Wageningen University
November 2011 Prospect theory and the brain, Cognitive Neuroscience Master Program,
Radboud University Nijmegen
Student (co)-supervision
2011-2012
Monique Timmer – PhD student
Ernest Mas Herrero – PhD student
Mahur Hashemi – MSc student
Jeff Martin – MSc student
Lieneke Janssen – Research assistant
Simone Heideman – Lab rotation
Yvonne Melzer – Lab rotation
Wei Zhang – Lab rotation
Maria Peltonen – Lab rotation
Yuen Fang – Lab rotation
Leticia Rettore Micheli – Lab rotation
2008-2011
Romain Ligneul – PhD student
Stéphanie Rogues – MSc student
Christophe Lenglos – MSc student
AD HOC REVIEWING
Addiction Biology
European Addiction Research
Journal of Neuroscience
NeuroImage
PLoS One
Social Cognitive and Affective Neuroscience
COLLABORATIONS
André Luxen, Cyclotron Research Centre, Liège, Belgium
Arnt Schellekens, UMC St Radboud Nijmegen, Netherlands
Guillaume Barbalat, Cambridge, UK
Jean-Claude Dreher, CNRS, Lyon, France
Luke Clark, Cambridge, UK
Marcel Janssen, UMC St Radboud Nijmegen, Netherlands
Mehdi Khamassi, CNRS, Paris, France
Miguel Ulla, CHU Clermont-Ferrand, France
Philip Gorwood, INSERM, Paris, France
Philippe Domenech, ENS/INSERM, Paris, France
Ruth van Holst, Donders Institute, Nijmegen, Netherlands
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MEDIA COVERAGE
National television/radio
“Le goût du fric”, Specimen program, aired on Swiss TV channel RTS, 17-11-2010
[www.rts.ch/emissions/specimen/2553637-specimen.html]
“Cerveau, sexe et argent”, Questions d'époque program, aired on French radio station France
Culture, 06/10/2010
[www.franceculture.fr/emission-questions-d-epoque-cerveau-sexe-et-argent-peter-gumbel-2010-10-06]
“Rien ne va plus”, L’Effet Papillon program, aired on French TV channel Canal+, 20/02/2010
[www.capatv.com/?p=5511]
“Pourquoi joue-t-on ?”, E=M6 program, aired on French TV channel M6, 12/12/2009
[www.m6.fr/emission-e_m6/13-12-2009-jeux_de_hasard_peut_on_forcer_la_chance-14286572.html]
[www.m6bonus.fr/videos-emissions-4/videos-e_m6-122/emission_du_13_12_2009/video-pourquoi_joue_t_on_-17108.html]
National newspapers/magazines
“Rien n’arrête la fièvre du jeu”, Sciences & Avenir magazine, June 2010
[www.sciencesetavenir.fr/magazine/actualite/098692/rien-n-arrete-la-fievre-du-jeu.html]
"Fric et sexe font chambre à part dans ce cerveau", Libération, 12/10/2010
[www.liberation.fr/vous/01012295707-fric-et-sexe-font-chambre-a-part-dans-le-cerveau]
"Le sexe et l’argent n’excitent pas le cerveau de la même façon", Le Figaro, 29/09/2010
[www.lefigaro.fr/sciences-technologies/2010/09/28/01030-20100928ARTFIG00813-sexe-et-argent-n-excitent-pas-lecerveau-de-la-meme-facon.php]
"Sexe et argent: à chaque plaisir sa zone cérébrale", L’Express, 29/09/2010
[www.lexpress.fr/actualite/sciences/sexe-et-argent-a-chaque-plaisir-sa-zone-cerebrale_923348.html]
"Oui, sexe et argent ne procurent pas le même plaisir", Le Point, 28/09/2010
[www.lepoint.fr/societe/oui-sexe-et-argent-ne-procurent-pas-le-meme-plaisir-28-09-2010-1242398_23.php]
SKILLS
Neuroscience
methods
functional Magnetic Resonance Imaging (fMRI), psychopharmacology, genetics
and hormones, skin conductance, eye-tracking, behavioral economics, psychiatric
assessment
Programming
& data analysis
Matlab, Statistica, Presentation, PsychToolbox, SPM8, MRIcroN, GingerALE,
Mango, BrainVISA, etc
MISCELLANEOUS
July-Dec 2008
Consultant for l’Oréal on the topic of “objective assessment of pleasure”
2010-2011
Collaboration with INRP (Institut National pour la Recherche Pédagogique) on an
online neuroimaging database used for teaching basic principle of neuroscience in
French highschools
[http://acces.ens-lyon.fr/acces/ressources/neurosciences/Banquedonnees_logicielneuroimagerie]
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