la dhea et le vieillissement
Transcription
la dhea et le vieillissement
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dédicaces JE DEDIE CE TRAVAIL...... A mon Père, A ma Mère, A mon Frère Mounir, A ma Sœur Farah, A tous mes Amis (es), A Mme Rose, Mes remerciements pour avoir rendu agréable la lecture de ce travail. A tous ceux qui, d’une manière ou d’une autre, m’ont aidé à l’élaboration de ce travail. Et à tous ceux que j’ aime A NOS MAITRES ET JUGES A Notre Maître et Président de Jury Le Professeur José Marie AFOUTOU, Le plaisir spontané et la joie que vous avez exprimés lorsque nous vous avons demandé de juger ce modeste travail, ne nous ont pas surpris. Vos connaissances étendues, votre esprit méthodique, votre droiture et votre conscience professionnelle vous ont valu l’admiration de tous. Nous nous enorgueillissons d’avoir été votre élève. Soyez assuré de notre indéfectible attachement et de notre profonde et vive gratitude. A Notre Maître et Juge Le Professeur Babacar FAYE, Vous nous faites un grand honneur en acceptant spontanément de juger ce travail malgré vos multiples occupations. Vous nous offrez ainsi l’occasion de vous remercier pour tous les enseignements que vous nous avez dispensés. Soyez assuré de nos sentiments les meilleurs. A Notre Maître et Juge Le Professeur Cheikh Saad Bouh BOYE, C’est un grand plaisir pour nous de vous compter parmi les membres @ de notre jury de thèse. Votre abord facile, votre disponibilité constante, votre modestie et votre courtoisie forcent l’admiration de tous ceux qui ont bénéficié de vos compétences. Veuillez trouver ici, l’assurance de notre profonde gratitude. A Notre Maître et Directeur de Thèse Le Professeur Mamadou BADIANE, J’ai le privilège et le grand honneur de vous avoir pour directeur de thèse. Malgré vos multiples tâches, vous avez accepté avec spontanéité et enthousiasme de faire l’honneur de siéger parmi nos juges. Vous m’avez toujours reçue avec une disponibilité constante. Vous représentez à mes yeux, un modèle, un exemple, une référence. Votre enseignement toujours dispensé avec méthode et clarté, votre humanisme, l’amour et la considération que vous affichez envers les étudiants sont une source d’émerveillement constant. Puisse ce travail vous exprimer notre profonde gratitude, notre respect et notre sincère reconnaissance. 7 $ ( *$%%.#'$ % ** '))"#" *'% %' 9$$%% !$# 0-%% $" # ."' $#.%)"'!% ( %' 9$: 1') ( "$"$# " ( )#" 4'#"'"$0 (###" ( J )"" K # ' 9$$%%$ : # (.$" (-A )$) ?$0 ' $. " (-# ?&$# ( 9$ ) )" %-$ (-'""$#( # %#&.9$". % & '#( .$( ('# % & ( %' )$#) " ('# %' .9#"$#: -" 0$ #*! A #" % ) ) 0$ L9#" ( " 9 # *( )#" % 44" #.4'" ( 9$$%%$*#": % "$*$" #'$#" %-'9$ " 9. .)**#" %' 4 * ( %' (.?( .$'#( ". # +/ !'"$. 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ii< $)%: (A ( #$ '##. %' " (9# # 9("" *.($'"$0: " '9 )" A*% # " $*'&$# 0 % !%$) $" G *L* ( -$#" & % !$#4'$" (-# "%% *%.)% " ' %G *L* (9#$ Q##A ( # 44$)')$".: "" ? *.($'"$'"$# ## 9. $4$. '$" ' %$ (-$#4 * $#($ # .%"'" $#9 : # )#.0#) % !%$) ($" ) ) ( ' &*#" )$#"$4$0 $" ' $" 4'$ # $(. .)$ ( *'& 9.$)%.: $ %' ## %' *$A '('". " %' % ) .#( G )"" '""#" *!% J #) K L" % ' *')$# (-44$)$#: % " (#) $* "'#" 0 )%$<)$ 4'$ 4') G ) .9%"$# $ !.#.4$)$ (-# 4 *'"$# )#"$# -' "$)%'#" # )%" )$#"$4$0 ( !' 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