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Institut d’Alembert - IFR 121
Applications des Lasers et Molécules aux Biotechnologies et Réseaux de Télecommunication
Séminaire
Vendredi 21 Mai 2008 - 11h
Salle de conférence du Bâtiment IDA
Chandrabhas NARAYANA
JNCASR, Bangalore, India
«Surface Enhanced Raman Spectroscopy in
biology: drug protein interactions and diagnostics»
S
urface Enhanced Raman Spectroscopy (SERS) though discovered
in early 70’s has been harnessed in the recent decade. SERS has
been developed to be a single molecular detection probe. With the
greater understanding of SERS, it has been possible to study biological systems by tailoring the metal nanoparticles.
he talk will have three parts. In the first part synthesis of nanoparticles, specifically core shell nanoparticles and hot-spots would
be discussed. The second part will deal with the use of SERS to study
the full lenth therapeutic proteins such as histone acetyltransferase
(HAT) protein p300 and its interaction with potential drug molecules
to develop improvements in the drugs. The third part deals with the
recent development of a diagnostic kit for HIV subtype as well as recombinant virus based on the SERS technique.
T
Institut d’Alembert :
ENS Cachan - 61, avenue du Président Wilson
94235 Cachan Cedex - France
Tél. : +33 1 47 40 21 47 - Fax : +33 1 47 40 20 65
e-mail : [email protected]
Site web : http://www.ida.ens-cachan.fr