UNITÉ DE RECHERCHE Centre de Recherche en Cancérologie de

Transcription

UNITÉ DE RECHERCHE Centre de Recherche en Cancérologie de
UNITÉ DE RECHERCHE
Centre de Recherche en Cancérologie de Marseille
DIRECTEUR : BORG Jean-Paul
ADRESSE : Institut Paoli Calmettes
27 Bd Lei Roure BP 30059 13273 Marseille
cedex 09
TELEPHONE : 04 86 97 72 00
COURRIEL : [email protected]
RATTACHEMENTS : AMU
INSERM
CNRS
IPC
POLES HOSPITALIERS :
3 - Imagerie Médicale (Intersites)
5 - Anapath-Digestif-Onco-Uro-Endocrinologie (Nord)
ECOLE DOCTORALE : Sciences de la Vie et de la Santé
(ED 062)
DISCIPLINES D’APPARTENANCES : DS 5 - Biologie, médecine, santé
SPECIALITÉS : Oncologie/Immunologie
GESTIONNAIRES DE L’UNITÉ : DUVIVIER Laurence
EFFECTIFS
Enseignants-Chercheurs :
14
Chercheurs EPST :
49
Autres Chercheurs :
36
IATOS/ITA :
66
Autres IATOS/ITA :
23
Doctorants :
54
Unité de Recherche. Centre de Recherche en Cancérologie de Marseille
1/23
PERSONNELS IMPLIQUÉS DANS LA RECHERCHE
Nom
Acquaviva
Acquaviva
Acunzo
Adélaïde
Afrache
Agnelli
Andrieu
Aouar
Aragnol
Arbiol
Arnoulet
Audebert
Audry
Aurrand-Lions
Baccini
Badache
Bailly
Bapin
Barbarat
Bardin
Baron-Gaillard
Barthet
Basse
Baty
Baudelet
Baylot
Benseddik
Benyamine
Bernard
Berthezene
Bertucci
Betzi
Bidaut
Birg
Prénom
Laurent
Claire
Julie
José
Hassnae
Lauren
Claudia
Besma
Denise
Christine
Christine
Stéphane
Julien
Michel
Michel
Ali
Éric
Luc
Bernadette
Florence
Carole
Marc
Marie jeanne
Daniel
Émilie
Virginie
Khedidja
Audrey
Stéphanie
Patrice
François
Stéphane
Ghislain
Françoise
statut
CR1
thèse
postdoc
Tech IPC
thèse
IE INSERM
thèse
thèse
PU
AI INSERM
PH
IR INSERM
thèse
CR1
TCN INSERM
DR2
CR1
TCN INSERM
THQ IPC
AI INSERM
postdoc
PU PH
AI INSERM
DR
AI INSERM
thèse
thèse
thèse
IE INSERM
IEH INSERM
PUPH
postdoc
IR2 INSERM
DR1
Birnbaum
Blaise
Bodin
Bonacci
Borg
Borge
Bourdely
Bourgeas
Boutchama
Brecqueville
Brisson
Brunel
Cabaud
Calmels
Camoin
Carbuccia
Carrier
Daniel
Didier
Jérome
Thomas
Jean-Paul
Laurence
Pierre
Raphaël
Henri
Mandy
Lydie
Jean michel
Olivier
Boris
Luc
Nadine
Alice
DR
MD – PU-PH
IE INSERM
Thèse
PU PH
AI INSERM
thèse
thèse
TCN INSERM
Thèse
Thèse
CR1
IE INSERM
PH
IR INSERM
AI INSERM
CR
Téléphone
04 91 16 43
04 86 97 72
04 86 97 72
04 91 22 33
04 86 97 73
04 91 82 88
04 86 97 72
04 86 97 72
04 91 16 43
04 91 16 43
04 91 22 33
04 91 22 33
04 91 16 45
04 86 97 72
04 86 97 72
04 86 97 73
04 86 97 72
04 86 97 73
04 86 97 73
04 86 97 72
04 86 97 73
04 91 82 88
04 91 16 45
04 91 82 88
04 91 22 33
04 86 97 72
04
04
04
04
04
04
04
04
54
04
04
04
04
04
66
62
66
04
41
35
66
72
66
21
76
07 ou 33 39
37
91
08
21
57
61
46
92
52
03
06
23
07
66
86
91
91
91
86
86
86
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16
82
22
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97
97
72
45
88
33
73
73
72
72
76
86
26
33 et poste 4779
33
01
06
61 ou 04 91 22 33
91
91
91
86
91
22
16
82
97
82
36
45
88
72
88
44
86
06
51
16
04 91 16 41 28
04 86 97 73 61 ou 73 65
Poste 4508
04
04
04
04
04
04
86
86
91
86
91
91
13
97
22
97
22
82
68
72
34
72
34
88
30
64
41
58
08
29
Unité de Recherche. Centre de Recherche en Cancérologie de Marseille
2/23
Castellano
Celis-Gutierrez
Cervera
Chabannon
Chaffanet
Chames
Charafe-jauffret
Charifi
Chetaille
Chetrit
Chevrier
Churikov
Collette
Combes
Coppin
Corda
Cornen
Coulier
Coulon
Daou
Daulat
David
de la Roche Saint André
De Sepulveda
Dehe
Derviaux
Devillier
Drivet
Drogat
Dubois
Dubreuil
Duprez
Dusetti
Duvivier
Fauriat
Ferrier
Finetti
Florentin
Fuchs
Fujii
Gaillard
Garcia
Garcia
Garcia
Garcia
Garzino
Gayet
Géli
Gelsi-Boyer
Geneix
Georges
Ghossoub
Gianardi
Gibier
Ginestier
Gonçalvès
Rémy
Javier
Nathalie
Christian
Max
Patrick
Emmanuelle
Férose
Bruno
Bernard
Véronique
Dmitri
Yves
Sébastien
Émilie
Yves
Stéphanie
François
Stéphane
Pascale
Avais
Guido
Christophe
Paulo
Pierre-Marie
Carine
Raynier
Elsa
Julie
Kenny
Patrice
Estelle
Nelson
Laurence
Cyril
Valérie
Pascal
Jonathan
Robert
Shingo
Pierre-Henri
Julie
Maria Noé
Maxime
Stéphane
Patrick
Odile
Vincent
Véronique
Jeannine
Coralie
Rania
Fabrice
Patrick
Christophe
Anthony
IR IPC
thèse
Tech IPC
PU
Cadre IPC
CR
PUPH
postdoc
MD PH
IE INSERM
IR1 INSERM
postdoc
DR2
MCU
thèse
CR1
thèse
CR1
CR1
thèse
postdoc
thèse
CR1
CR1
postdoc
thèse
thèse
thèse
postdoc
IE INSERM
DR1
DR2
DR2
AI INSERM
CR2
Cadre IPC
Tech IPC
thèse
DRCE
CR1
CR1
thèse
thèse
thèse
thèse
TCE INSERM
IE INSERM
DR1
MCU
Tech IPC
AI INSERM
Post-Doc
TN INSERM
AI INSERM
CR2
PH
04 86 97 73
04 86 97 72
04 91 22 33
04 91 22 34
04 91 22 34
04 91 82 88
04 91 22 35
04 91 16 43
04 91 22 34
04 86 97 72
04 86 97 72
04 91 16 43
04 86 97 73
04 91 28 82
04 86 97 72
04 91 16 45
Poste 4508
04 86 97 72
04 91 16 45
04 86 97 73
04 86 97 72
32
74
04
41
77
33
09
55
57
07
64
55
31
91
74
80
07
34
21
55
04 91 16 43 66
04 86 97 72 85
04 91 16 42 66
Poste 4508
04
04
04
04
04
04
04
04
04
04
04
04
04
04
04
04
04
04
04
04
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04
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04
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04
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91
86
86
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86
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16
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82
97
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22
22
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16
16
82
82
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82
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82
16
22
22
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26
97
22
22
43
43
72
73
88
72
73
33
33
72
42
43
42
88
88
73
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73
88
45
41
40
72
73
91
73
35
33
55
21
81
11
28
04
47
52
04
72
71
69
72
15
36
02
22
62
27
32
75
73
83
52
38
62
09
11
Unité de Recherche. Centre de Recherche en Cancérologie de Marseille
3/23
Gondois-Rey
Goubard
Granjeaud
Grasso
Guenneau-Puvirajesinghe
Guervilly
Guillaumond
Guille
Hamidi
Hammam
Hamon
Hardy
Hirsch
Imbert
Iovanna
Isnardon
Isogawa
Josselin
Jourquin
Just-Landi
Ka
Karaki
Kashyap
Katsogiannou
Kerfelec
Koubi
Laloum
Launay
Lavaut
Le
Le Roy
Leca
Lecocq
Lembo
Letard
Letessier
Lhoumeau
Lissitzky
Liu
Livrati
Llorente
Lombard
Loncle
Lopez
Lopez
Luciano
Malenfant
Mallet
Maneville
Marchetto
Martinez
Mezil
Mille
Modesti
Moldawan
Monges
Françoise
Armelle
Samuel
Daniel
Tania
Jean-Hugues
Fabienne
Arnaud
Tewfik
Kahina
Veronique
Julien
Ivan
Anne-Marie
Juan
Daniel
Asako
Emmanuelle
Frédéric
Sylvaine
Mignane
Sara
Rudra
Maria
Brigitte
Myriam
Laurence
Simon
Marie-Noëlle
Suong
Aude
Julie
Éric
Frédérique
Sébastien
Anne
Anne-Catherine
Jean-Claude
Xiaoxuan
Philippe
Bertrand
Benjamin
Céline
Marc
Sophie
Pierre
Carine
Françoise
Stéphanie
Sylvie
Sébastien
Lynda
Delphine
Mauro
Yvonne
Geneviève
IR2 INSERM
THQ IPC
IR1 INSERM
thèse
Post-Doc
postdoc
postdoc
IE INSERM
thèse
thèse
postdoc
thèse
DR
THQ IPC
DR1
IR IPC
IR CNRS
AI INSERM
IE CNRS
Tech IPC
thèse
Thèse
thèse
postdoc
CR
thèse
TCN INSERM
thèse
IE AMU
thèse
thèse
thèse
TCE INSERM
THQ IPC
Tech AMU
CR2
thèse
CR1
postdoc
Tech IPC
CR1
IE INSERM
IE INSERM
IR INSERM
IR INSERM
CR1
Tech INSERM
Tech IPC
thèse
IR2 INSERM
thèse
thèse
TCN INSERM
DR2
ATP INSERM
PH
04 86 97 72 76
04 86 97 73 32
04 86 97 73 01
04
04
04
04
04
04
04
04
04
04
04
04
04
04
04
04
86
91
91
91
91
86
91
91
86
91
91
86
91
86
91
86
97
16
82
22
82
97
16
16
97
22
82
97
16
97
16
97
72
42
88
33
88
72
41
45
72
34
88
73
43
72
43
73
55
66
06
04
15
84
28
37
71
37
03
64
69
63
55
45
04
04
04
04
04
86
86
91
86
86
97
97
82
97
97
73
72
88
73
72
52
66
33
12
02
04 91 82 88
04 86 97 72
04 86 97 73
04 91 82 88
04 86 97 72
04 86 97 73
04 86 97 72
Poste 4508
04 86 97 72
04 86 97 72
04 86 97 72
04 86 97 73
04 91 16 43
04 91 82 88
04 91 82 88
04 86 97 72
04 86 97 72
04 91 16 45
04 91 22 34
04 86 97 73
04 91 16 41
04 86 97 72
04 86 97 72
04 86 97 72
04 86 97 73
04 91 16 43
04 86 97 73
04 91 22 34
22
76
41
36
84
52
82
54
93
66
45
21
35
15
61
83
80
46
44
28
53
52
63
62
48
61
57
Unité de Recherche. Centre de Recherche en Cancérologie de Marseille
4/23
Morazzani
Morelli
Morin
Mosca
Mozziconacci
Murati
Naiman
Négrel
Nevoltris
Nigri
Nunès
Olivares
Olive
Olivares
Olivier
Orlanducci
Orsoni
Pages
Betty
Xavier
Stéphanie
Cyndie
Marie-Joëlle
Anne
Karel
Aurélie
Damien
Jérémy
Jacques
Orianne
Daniel
Orianne
Bruno
Florence
Jean-Christophe
Vincent
Palud
Pasero
Pastor
Peltier
Peuget
Philippin
Pinet
Platet
Adeline
Christine
Sonia
Julien
Sylvain
Gaëlle
Isabelle
Nadine
Poinsignon
Pophillat
Pouyet
Prébet
Receveur-Bréchot
Restouin
Rey
Rocchi
Rochas
Roche
Rosnet
Roubin
Roux
Rovere
Sabatier
Salaun
Salvador
Santoni
Sari
Scaglione
Sebbagh
Secq
Seillier
Simon
Skrobuk
Sonongbua
Catherine
Matthieu
Laurent
Thomas
Véronique
Audrey
Jérôme
Palma
Caroline
Philippe
Olivier
Régine
Claude
Julie
Renaud
Danièle
Marion
Marie-Josée
Karim
Sarah
Michaël
Véronique
Marion
Marie-Noëlle
Paulina
Ying
TCE INSERM
CR1
thèse
IE INSERM
PH
PH
postdoc
IE INSERM
thèse
Tech IPC
DR
thèse
PU PH
thèse
ATP2 IPC
Tech IPC
TCE INSERM
CR2
Chercheur
contractuel
CNRS
postdoc
AI INSERM
thèse
thèse
IE CNRS
TCE CNRS
IR CNRS
Chercheur
contractuel
CNRS (CEFIC)
IE INSERM
postdoc
PH
DR
THQ
thèse
CR1
IE INSERM
CR
CR1
CR1
IE INSERM
Tech IPC
med
AI INSERM
thèse
CR1
TN INSERM
AI INSERM
CR1
med
IE INSERM
CR1
postdoc
thèse
05 86 97 73 33
04 86 97 73 31
04
04
04
04
04
04
04
04
04
04
86
91
91
91
91
91
91
86
91
86
97
22
22
16
16
82
82
97
82
97
72
33
41
43
45
88
88
72
88
72
84
77
75
30
86
34
15
74
36
71
04
04
04
04
91
86
86
91
82
97
97
16
88
73
73
43
29
44
62
30
04
04
04
04
04
04
04
86
86
91
91
91
91
86
97
97
22
82
16
16
97
73
72
33
88
43
41
73
47
76
07
27
94
69
12
04
04
04
04
04
86
86
91
91
86
97
97
22
16
97
72
73
36
45
73
59
32
95
01
32
04
04
04
04
04
04
04
04
04
86
86
91
86
86
86
86
91
86
97
97
16
97
97
97
97
22
97
72
73
45
72
72
72
72
33
73
67
42
06
65
65
05
01
04
21
04
04
04
04
04
04
04
04
86
91
91
86
91
91
91
91
97
82
16
97
82
82
16
82
72
88
42
72
88
88
45
88
56
29
66
57
22
29
37
15
Unité de Recherche. Centre de Recherche en Cancérologie de Marseille
5/23
Soubeyran
Soucie
Spoto
Stahl
Stranska
Taieb
Takedachi
Tardivel-Lacombe
Termine
Tiberi
Toiron
Tomasini
Torres
Tournaire
Traore
Turini
Van Hiel
Vasseur
Verdier-Pinard
Verdiglione
Vey
Viens
Vincent-Fabert
Vita
Wicinski
Xerri
Yagi
Yahiaoui
Zhang
Zimmermann
Philippe
Erinn
Patricia
Olivier
Ružena
David
Arato
Joël
Elise
Guillaume
Yves
Richard
Martine
Roselyne
Wilfried
Marc
Boris
Sophie
Pascal
Noémie
Norbert
Patrice
Christelle
Marina
Julien
Luc
Yoshihiko
Imène
Xu
Pascale
CR1
postdoc
TN INSERM
THQ IPC
postdoc
PU PH
postdoc
IE1D INSERM
IE2 INSERM
IE INSERM
Technicien IPC
CR1
AJT CNRS
MCU
thèse
thèse
thèse
CR1
CR1
IE INSERM
PH
PUPH
postdoc
postdoc
Tech IPC
PU PH
IE INSERM
thèse
thèse
DR
04
04
04
04
04
04
04
04
04
04
04
04
04
04
04
04
91
86
91
86
86
86
91
91
91
86
86
91
91
91
86
91
82
97
82
97
97
97
16
82
82
97
97
82
16
82
97
82
88
72
88
73
72
72
42
88
88
73
72
88
41
88
72
88
07
83
29
02
72
67
66
04
33
12
53
15
79
05
52
24
04
04
04
04
04
04
04
04
04
04
04
04
04
91
86
86
91
91
86
86
91
91
91
86
86
86
82
97
97
22
22
97
97
22
22
16
97
97
97
88
73
73
37
37
73
72
34
34
43
73
72
73
06
21
12
54
78
12
85
08
57
94
41
66
51
EQUIPES DE RECHERCHE et THEMATIQUES
EQUIPE : E1 - Molecular Oncology
RESPONSABLE : BIRBAUM Daniel
EQUIPE : E2 - Cell Polarity, Cell Signaling and Cancer
RESPONSABLE : BORG Jean-Paul
EQUIPE : E3 - Signalling, haematopoiesis and mechanisms of oncogenesis
RESPONSABLE : DUBREUIL Patrice
EQUIPE : E4 - Tumor Cell Motility
RESPONSABLE : BADACHE Ali
EQUIPE : E5 - Adhésion Molecules in Tumour/host Interactions
RESPONSABLE : AURRAND-LIONS Michel
EQUIPE : E6 - Epigenetic control of normal and pathological hematopiesis
RESPONSABLE : DUPREZ Estelle
EQUIPE : E7 - PDZ scaffold proteins and phosphoinoslitides in cell signalling and oncogenesis
RESPONSABLE : ZIMMERMANN Pascale
EQUIPE : E8 - Cell stress
RESPONSABLE : IOVANNA Juan
Unité de Recherche. Centre de Recherche en Cancérologie de Marseille
6/23
EQUIPE : E9 - Tolerance of lesions in DNA
RESPONSABLE : FUCHS Robert
EQUIPE : E10 - Tolerance, Senescence and DNA damage
RESPONSABLE : GELI Vincent
EQUIPE : E11 - Mechanisms of DNA double-strand break repair system : homologous
recombination and NHEJ
RESPONSABLE : MODESTI Mauro
EQUIPE : E12 - Control of structure-specific endonucleases and genome stability
RESPONSABLE : GAILLARD Pierre-Henri
EQUIPE : E13 - Genome dynamics and recombination
RESPONSABLE : Llorente Bertrand
EQUIPE : E14 - Immunity & Cancer
RESPONSABLE : OLIVE Daniel
EQUIPE : E15 - Fundamental & Therapeutic Chemical Biology
RESPONSABLE : COLLETTE Yves
EQUIPE : E16 - Antibody Therapeutics & Immunotargeting
RESPONSABLE : BATY Daniel
PERSONNELS PAR EQUIPE DE RECHERCHE
EQUIPE : E1 - Molecular Oncology
RESPONSABLE : BIRBAUM Daniel
Acquaviva
Acunzo
Adélaïde
Andrieu
Baylot
Bertucci
Birnbaum
Brecqueville
Cabaud
Carbuccia
Cervera
Chaffanet
Charafe-jauffret
Chevrier
Cornen
Devillier
Finetti
Gelsi-Boyer
Geneix
Ginestier
Guille
Josselin
Karaki
Katsogiannou
Launay
Letessier
Liu
Lopez
Claire
Julie
José
Claudia
Virginie
François
Daniel
Mandy
Olivier
Nadine
Nathalie
Max
Emmanuelle
Véronique
Stéphanie
Raynier
Pascal
Véronique
Jeannine
Christophe
Arnaud
Emmanuelle
Sara
Maria
Simon
Anne
Xiaoxuan
Marc
Unité de Recherche. Centre de Recherche en Cancérologie de Marseille
7/23
Mezil
Monges
Mozziconacci
Murati
Rocchi
Rosnet
Roubin
Sabatier
Salvador
Taieb
Viens
Wicinski
Lynda
Geneviève
Marie-Joëlle
Anne
Palma
Olivier
Régine
Renaud
Marion
David
Patrice
Julien
EQUIPE : E2 - Cell Polarity, Cell Signaling and Cancer
RESPONSABLE : BORG Jean-Paul
Bailly
Borg
Daulat
Gonçalvès
Guenneau-Puvirajesinghe
Lhoumeau
Marchetto
Martinez
Prébet
Santoni
Sebbagh
Toiron
Traore
Audebert
Baudelet
Camoin
Peltier
Pophillat
Éric
Jean-Paul
Avais
Anthony
Tania
Anne-Catherine
Sylvie
Sébastien
Thomas
Marie-Josée
Michaël
Yves
Wilfried
Stéphane
Émilie
Luc
Julien
Matthieu
EQUIPE : E3 - Signalling, haematopoiesis and mechanisms of oncogenesis
RESPONSABLE : DUBREUIL Patrice
De Sepulveda
Dubreuil
Georges
Hammam
Lecocq
Letard
Lopez
Mosca
Soucie
Vita
Paulo
Patrice
Coralie
Kahina
Éric
Sébastien
Sophie
Cyndie
Erinn
Marina
EQUIPE : E4 - Tumor Cell Motility
RESPONSABLE : BADACHE Ali
Badache
Benseddik
Daou
Salaun
Verdier-Pinard
Ali
Khedidja
Pascale
Danièle
Pascal
Unité de Recherche. Centre de Recherche en Cancérologie de Marseille
8/23
EQUIPE : E5 - Adhésion Molecules in Tumour/host Interactions
RESPONSABLE : AURRAND-LIONS Michel
Aurrand-Lions
Bardin
Lissitzky
Michel
Florence
Jean-Claude
EQUIPE : E6 - Epigenetic control of normal and pathological hematopiesis
RESPONSABLE : DUPREZ Estelle
Calmels
Chabannon
Duprez
Imbert
Koubi
Platet
Tiberi
Verdiglione
Vincent-Fabert
Boris
Christian
Estelle
Anne-Marie
Myriam
Nadine
Guillaume
Noémie
Christelle
EQUIPE : E7 - PDZ scaffold proteins and phosphoinoslitides in cell signalling and oncogenesis
RESPONSABLE : ZIMMERMANN Pascale
Baron-Gaillard
David
Ghossoub
Kashyap
Lembo
Van Hiel
Zimmermann
Carole
Guido
Rania
Rudra
Frédérique
Boris
Pascale
EQUIPE : E8 - Cell stress
RESPONSABLE : IOVANNA Juan
Barthet
Berthezene
Bonacci
Borge
Brisson
Carrier
Dusetti
Garcia
Garcia
Garcia
Gayet
Gianardi
Grasso
Guillaumond
Hamidi
Iovanna
Lavaut
Leca
Loncle
Nigri
Olivares
Olivier
Marc
Patrice
Thomas
Laurence
Lydie
Alice
Nelson
Julie
Maria Noé
Stéphane
Odile
Fabrice
Daniel
Fabienne
Tewfik
Juan
Marie-Noëlle
Julie
Céline
Jérémy
Orianne
Bruno
Unité de Recherche. Centre de Recherche en Cancérologie de Marseille
9/23
Peuget
Sari
Secq
Seillier
Skrobuk
Soubeyran
Spoto
Tardivel-Lacombe
Tomasini
Tournaire
Vasseur
Sylvain
Karim
Véronique
Marion
Paulina
Philippe
Patricia
Joël
Richard
Roselyne
Sophie
EQUIPE : E9 - Tolerance of lesions in DNA
RESPONSABLE : FUCHS Robert
FUCHS Robert
FUJII Shingo
ISOGAWA Asako
PAGES Vincent
PALUD Adeline
PHILIPPIN Gaëlle
POINSIGNON Catherine
DR INSERM
IR CNRS
IR CNRS
CR CNRS
Chercheur contractuel CNRS
IE CNRS
Chercheur contractuel CNRS (CEFIC)
EQUIPE : E10 - Tolemère, Senescence and DNA damage
RESPONSABLE : GELI Vincent
Acquaviva
Aragnol
Audry
Charifi
Churikov
Corda
Coulon
de la Roche Saint André
Drogat
Géli
Hardy
Jourquin
Luciano
Simon
Torres
Laurent
Denise
Julien
Férose
Dmitri
Yves
Stéphane
Christophe
Julie
Vincent
Julien
Frédéric
Pierre
Marie-Noëlle
Martine
EQUIPE : E11 - Mechanisms of DNA double-strand break repair system : homologous
recombination and NHEJ
RESPONSABLE : MODESTI Mauro
Bernard
Bodin
Modesti
Négrel
Stéphanie
Jérome
Mauro
Aurélie
EQUIPE : E12 - Control of structure-specific endonucleases and genome stability
RESPONSABLE : GAILLARD Pierre-Henri
Dehe
Gaillard
Guervilly
Scaglione
Takedachi
Pierre-Marie
Pierre-Henri
Jean-Hugues
Sarah
Arato
Unité de Recherche. Centre de Recherche en Cancérologie de Marseille
10/23
EQUIPE : E13 - Genome dynamics and recombination
RESPONSABLE : Llorente Bertrand
Arbiol
Dubois
Llorente
Christine
Kenny
Bertrand
EQUIPE : E14 - Immunity & Cancer
RESPONSABLE : OLIVE Daniel
Afrache
Aouar
Arnoulet
Barbarat
Benyamine
Blaise
Bourdely
Celis-Gutierrez
Chetaille
Coppin
Fauriat
Florentin
Gondois-Rey
Hirsch
Just-Landi
Ka
Le
Le Roy
Livrati
Mallet
Morin
Nunès
Olive
Orlanducci
Pasero
Pastor
Rey
Rochas
Sonongbua
Stranska
Vey
Xerri
Yahiaoui
Hassnae
Besma
Christine
Bernadette
Audrey
Didier
Pierre
Javier
Bruno
Émilie
Cyril
Jonathan
Françoise
Ivan
Sylvaine
Mignane
Suong
Aude
Philippe
Françoise
Stéphanie
Jacques
Daniel
Florence
Christine
Sonia
Jérôme
Caroline
Ying
Ružena
Norbert
Luc
Imène
EQUIPE : E15 - Fundamental & Therapeutic Chemical Biology
RESPONSABLE : COLLETTE Yves MORELLI Xavier
Basse
Betzi
Bourgeas
Brunel
Castellano
Chetrit
Collette
Combes
Derviaux
Marie jeanne
Stéphane
Raphaël
Jean michel
Rémy
Bernard
Yves
Sébastien
Carine
Unité de Recherche. Centre de Recherche en Cancérologie de Marseille
11/23
Drivet
Goubard
Hamon
Maneville
Morazzani
Morelli
Pouyet
Receveur-Bréchot
Restouin
Roche
Zhang
Elsa
Armelle
Veronique
Stéphanie
Betty
Xavier
Laurent
Véronique
Audrey
Philippe
Xu
EQUIPE : E16 - Antibody Therapeutics & Immunotargeting
RESPONSABLE : BATY Daniel
Agnelli
Baty
Chames
Kerfelec
Lombard
Nevoltris
Rozan
Termine
Turini
Lauren
Daniel
Patrick
Brigitte
Benjamin
Damien
Caroline
Elise
Marc
EQUIPE : E17 - BIOINFORMATIQUE INTEGRATIVE
Bidaut
Ghislain
Garcia
Maxime
Granjeaud
Samuel
EQUIPE : E18 - SERVICES COMMUNS
Baccini
Michel
Bapin
Luc
Birg
Françoise
Boutchama
Henri
Coulier
François
Granjeaud
Samuel
Garzino
Patrick
Gibier
Patrick
Isnardon
Daniel
Laloum
Laurence
Mille
Delphine
Moldawan
Yvonne
Orsoni
Jean-Christophe
Pinet
Isabelle
Roux
Claude
Rovere
Julie
Unité de Recherche. Centre de Recherche en Cancérologie de Marseille
12/23
PUBLICATIONS ANNÉES 2010 et 2011
1. Acquaviva,C., Gelsi-Boyer, V., and Birnbaum, D. Myelodysplastic syndromes: lost between two
states? Leukemia. 2010;24:1-5.
2. Addou-Klouche,L., Adelaide, J., Finetti, P., Cervera, N., Ferrari, A., Bekhouche, I., Sircoulomb,
F., Sotiriou, C., Viens, P., Moulessehoul, S., Bertucci, F., Birnbaum, D., and Chaffanet, M. Loss,
mutation and deregulation of L3MBTL4 in breast cancers. Molecular Cancer. 2010;9:2133. Adelaide,J., Gelsi-Boyer, V., Rocquain, J., Carbuccia, N., Birnbaum, D. J., Finetti, P., Bertucci, F.,
Mozziconacci, M. J., Vey, N., Birnbaum, D., and Chaffanet, M. Gain of CBL-interacting protein, a
possible alternative to CBL mutations in myeloid malignancies. Leukemia. 2010;24:1539-1541.
4. Bertucci,F., Finetti, P., Sabatier, R., and Birnbaum, D. The CINSARC signature: prognostic and
predictive of response to chemotherapy? Cell Cycle. 2010;9:4025-4027.
5. Bertucci,F., Finetti, P., Birnbaum, D., and Viens, P. Gene expression profiling of inflammatory
breast cancer. Cancer. 2010;116:2783-2793.
6. Bidaut, G. Interpreting and Comparing Clustering Experiments Through Graph Visualization and
Ontology Statistical Enrichment with the ClutrFree Package. Biomedical Informatics for Cancer
Research. [19], 315-333. 2010.
Ref Type: Book Chapter
7. Birnbaum,D.J., Sabatier, R., Mamessier, E., Birnbaum, D., and Bertucci, F. Une forme «
ariditaire » du cancer de l'ovaire. M/S Medecine Sciences. 2010;26:1040-1042.
8. Carbuccia,N., Trouplin, V., Gelsi-Boyer, V., Murati, A., Rocquain, J., Adelaide, J., Olschwang, S.,
Xerri, L., Vey, N., Chaffanet, M., Birnbaum, D., and Mozziconacci, M. J. Mutual exclusion of ASXL1
and NPM1 mutations in a series of acute myeloid leukemias. Leukemia. 2010;24:469-473.
9. Chabannon,C., Honstettre, A., Daufresne, L. M., Martin, P. M., Bonnetaud, C., BirtwislePeyrottes, I., Romain, S., Achache, K., Mery, O., Bordonne, O., Ducord, C., Jacotot, L., Vaglio, P.,
d'Arnoux, C., Figarella-Branger, D., Hofman, P., Borg, J. P., and Atger, V. Publication of biological
samples collections catalogues by tumor banks. La publication de catalogues de collections
d'échantillons biologiques par les tumorothèques. Bulletin du Cancer. 2010;97:181-189.
10. Chapiro,E., Russell, L., Lainey, E., Kaltenbach, S., Ragu, C., Della-Valle, V., Hanssens, K.,
Macintyre, E. A., Radford-Weiss, I., Delabesse, E., Cave, H., Mercher, T., Harrison, C. J., NguyenKhac, F., Dubreuil, P., and Bernard, O. A. Activating mutation in the TSLPR gene in B-cell precursor
lymphoblastic leukemia. Leukemia. 2010;24:642-645.
11. Charafe-Jauffret,E., Ginestier, C., Iovino, F., Tarpin, C., Diebel, M., Esterni, B., Houvenaeghel,
G., Extra, J. M., Bertucci, F., Jacquemier, J., Xerri, L., Dontu, G., Stassi, G., Xiao, Y., Barsky, S. H.,
Birnbaum, D., Viens, P., and Wicha, M. S. Aldehyde Dehydrogenase 1-Positive Cancer Stem Cells
Mediate Metastasis and Poor Clinical Outcome in Inflammatory Breast Cancer. Clinical Cancer
Research. 2010;16:45-55.
12. Charafe-Jauffret,E., Ginestier, C., and Birnbaum, D. Cancer stem cells: Just sign here! Cell
Cycle. 2010;9:229-230.
13. Coursindel,T., Restouin, A., Dewynter, G., Martinez, J., Collette, Y., and Parrot, I.
Stereoselective ring contraction of 2,5-diketopiperazines: an innovative approach to the synthesis
of promising bioactive 5-membered scaffolds. Bioorganic Chemistry. 2010;38:210-217.
14. De Lavallade,H., Finetti, P., Carbuccia, N., Khorashad, J. S., Charbonnier, A., Foroni, L.,
Apperley, J. F., Vey, N., Bertucci, F., Birnbaum, D., and Mozziconacci, M. J. A gene expression
signature of primary resistance to imatinib in chronic myeloid leukemia. Leukemia Research.
2010;34:254-257.
Unité de Recherche. Centre de Recherche en Cancérologie de Marseille
13/23
15. Derre,L., Rivals, J. P., Jandus, C., Pastor, S., Rimoldi, D., Romero, P., Michielin, O., Olive, D.,
and Speiser, D. E. BTLA mediates inhibition of human tumor-specific CD8+ T cells that can be
partially reversed by vaccination. Journal of Clinical Investigation. 2010;120:157-167.
16. Fei,F., Kweon, S. M., Haataja, L., De Sepulveda, P., Groffen, J., and Heisterkamp, N. The Fer
tyrosine kinase regulates interactions of Rho GDP-Dissociation Inhibitor a with the small GTPase
Rac. BMC Biochemistry. 2010;11:4817. Fournier,G., Garrido-Urbani, S., Reymond, N., and Lopez, M. Nectin and nectin-like molecules
as markers, actors and targets in cancer. M/S Medecine Sciences. 2010;26:273-280.
18. Gelsi-Boyer,V., Trouplin, V., Roquain, J., Adelaide, J., Carbuccia, N., Esterni, B., Finetti, P.,
Murati, A., Arnoulet, C., Zerazhi, H., Fezoui, H., Tadrist, Z., Nezri, M., Chaffanet, M., Mozziconacci,
M. J., Vey, N., and Birnbaum, D. ASXL1 mutation is associated with poor prognosis and acute
transformation in chronic myelomonocytic leukaemia. British Journal of Haematology.
2010;151:365-375.
19. Ghiotto,M., Gauthier, L., Serriari, N., Pastor, S., Truneh, A., Nunes, J. A., and Olive, D. PD-L1
and PD-L2 differ in their molecular mechanisms of interaction with PD-1. International
Immunology. 2010;22:651-660.
20. Gilabert,M., Audebert, S., Viens, P., Borg, J. P., Bertucci, F., and Goncalves, A. Proteomics and
breast cancer: a search for novel diagnostic and theragnostic biomarkers. Bulletin du Cancer.
2010;97:321-339.
21. Ginestier,C., Charafe-Jauffret, E., and Birnbaum, D. Targeting breast cancer stem cells: fishing
season open! Breast Cancer Research. 2010;12:31222. Ginestier,C., Liu, S., Diebel, M. E., Korkaya, H., Luo, M., Brown, M., Wicinski, J., Cabaud, O.,
Charafe-Jauffret, E., Birnbaum, D., Guan, J. L., Dontu, G., and Wicha, M. S. CXCR1 blockade
selectively targets human breast cancer stem cells in vitro and in xenografts. Journal of Clinical
Investigation. 2010;120:485-497.
23. Giusiano,S., Secq, V., Carcopino, X., Carpentier, S., Andrac, L., Lavaut, M. N., Allasia, C.,
Bonnier, P., Iovanna, J. L., Garcia, S., Boubli, L., Birnbaum, D., and Charpin, C.
Immunohistochemical profiling of node negative breast carcinomas allows prediction of metastatic
risk. International Journal of Oncology. 2010;36:889-898.
24. Guittard,G., Mortier, E., Tronchere, H., Firaguay, G., Gerard, A., Zimmermann, P., Payrastre,
B., and Nunes, J. A. Evidence for a positive role of PtdIns5P in T-cell signal transduction pathways.
FEBS Letters. 2010;584:2455-2460.
25. Hahn,K.A., Legendre, A. M., Shaw, N. G., Phillips, B., Ogilvie, G. K., Prescott, D. M., Atwater,
S. W., Carreras, J. K., Lana, S. E., Ladue, T., Rusk, A., Kinet, J. P., Dubreuil, P., Moussy, A., and
Hermine, O. Evaluation of 12- and 24-month survival rates after treatment with masitinib in dogs
with nonresectable mast cell tumors. American Journal of Veterinary Research. 2010;71:13541361.
26. Hirsch,I., Caux, C., Hasan, U., Bendriss-Vermare, N., and Olive, D. Impaired Toll-like receptor
7 and 9 signaling: from chronic viral infections to cancer. Trends in Immunology. 2010;31:391397.
27. Hudson,T., Anderson, W., Aretz, A., Bell, C., Bernabe, R., Bhan, M., Calvo, F., Eerola, I.,
Gerhard, D., Guttmacher, A., Guyer, M., Hemsley, F., Jennings, J., Kerr, D., Klatt, P., Kolar, P.,
Lane, D., Laplace, F., Nettekoven, G., Ozenberger, B., Peterson, J., Rao, T., Remacle, J., Schafer,
A., Shibata, T., Stratton, M., Watanabe, K., Yuen, M., Cambon-Thomsen, A., Dressler, L., Joly, Y.,
Kennedy, K., Parker, M., Romeo-Casabona, C., Wallace, S., Wiesner, G., Zeps, N., Biankin, A.,
Chabannon, C., de Alava, E., Ferguson, M., Geary, P., Hayes, N., Johns, A., Kasprzyk, A.,
Nakagawa, H., Piris, M., van de Vijver, M., Aburatani, H., Bayes, M., Bowtell, D., Campbell, P.,
Hirst, M., Lopez-Otin, C., Marra, M., Ning, Z., Puente, X., Ruan, Y., Stunnenberg, H., Swerdlow, H.,
Velculescu, V., Xue, H., Yang, L., Spellman, P., Bader, G., Boutros, P., Flicek, P., Getz, G., Guigo,
R., Guo, G., Haussler, D., Hubbard, T., Jiang, T., Jones, S., Li, Q., Lopez-Bigas, N., Luo, R.,
Muthuswamy, L., Ouellette, F., Pearson, J., Quesada, V., Raphael, B., Sander, C., Stein, L., Stuart,
J., Teague, J., Totoki, Y., Tsunoda, T., Valencia, A., Wheeler, D., Wu, H., Zhao, S., Zhou, G.,
Unité de Recherche. Centre de Recherche en Cancérologie de Marseille
14/23
Lathrop, M., Axton, M., Dyke, S., Gunter, C., McPherson, J., Miller, L., Zhang, J., Haider, S., Wang,
J., Yung, C., Cross, A., Liang, Y., Gnaneshan, S., Guberman, J., Hsu, J., Bobrow, M., Chalmers, D.,
Hasel, K., Kaan, T., Knoppers, B., Lowrance, W., Masui, T., Nicolas, P., Rial-Sebbag, E., Rodriguez,
L., Vergely, C., Grimmond, S., Bowtell, D., Cloonan, N., deFazio, A., Eshleman, J.,
Etemadmoghadam, D., Gardiner, B., Kench, J., Scarpa, A., Sutherland, R., Tempero, M., Waddell,
N., Wilson, P., Gallinger, S., Tsao Ming, S., Shaw, P., Petersen, G., Mukhopadhyay, D., Chin, L.,
DePinho, R., Thayer, S., Shazand, K., Beck, T., Sam, M., Timms, L., Ballin, V., Ji, J., Zhang, X.,
Chen, F., Hu, X., Yang, Q., Tian, G., Zhang, L., Xing, X., Li, X., Zhu, Z., Yu, Y., Yu, J., Yang, H.,
Tost, J., Brennan, P., Holcatova, I., Zaridze, D., Brazma, A., Egevad, L., Prokhortchouk, E., Banks,
R., Uhlen, M., Viksna, J., Ponten, F., Skryabin, K., Futreal, A., Birney, E., Caldas, C., Reis-Filho, J.,
Richardson, A., Sotiriou, C., Birnbaum, D., Blanche, H., Boucher, P., Boyault, S., Jacquemier, J.,
Pauporte, I., Pivot, X., Vincent-Salomon, A., Tabone, E., Theillet, C., Treilleux, I., Bioulac-Sage, P.,
Clement, B., Decaens, T., Degos, F., Franco, D., Gut, I., Gut, M., Heath, S., Samuel, D., Thomas,
G., Zucman-Rossi, J., Eils, R., Brors, B., Korbel, J., Korshunov, A., Landgraf, P., Lehrach, H.,
Pfister, S., Radlwimmer, B., Reifenberger, G., Taylor, M., von Kalle, C., Majumder, P., Sarin, R.,
Pederzoli, P., Lawlor, R., Delledonne, M., Bardelli, A., Gress, T., Klimstra, D., Zamboni, G.,
Nakamura, Y., Kusuda, J., Miyano, S., Kato, K., Fujimoto, A., Yoshida, T., Campo, E., Estivill, X., de
Sanjose, S., Montserrat, E., Gonzalez-Diaz, M., Himmelbaue, H., Bea, S., Aparicio, S., Borg, A.,
Borresen-Dale, A. L., Foekens, J., van't Veer, L., Easton, D., Martin, S., Compton, C., Lander, E.,
Penny, R., Shaw, K., Speed, T., Vockley, J., Lichter, P., Barker, A., Burke, W., Collins, F., Green,
A., Hamilton, S., Kallioniemi, O., Ley, T., Liu, E., and Lu, Y. International network of cancer
genome projects. Nature. 2010;464:993-998.
28. Humbert,M., Casteran, N., Letard, S., Hanssens, K., Iovanna, J., Finetti, P., Bertucci, F., Bader,
T., Mansfield, C. D., Moussy, A., Hermine, O., and Dubreuil, P. Masitinib combined with standard
gemcitabine chemotherapy: in vitro and in vivo studies in human pancreatic tumour cell lines and
ectopic mouse model. PLoS ONE. 2010;5:e943029. Kosmider,O., Gelsi-Boyer, V., Slama, L., Dreyfus, F., Beyne-Rauzy, O., Quesnel, B., HunaultBerger, M., Slama, B., Vey, N., Lacombe, C., Solary, E., Birnbaum, D., Bernard, O. A., and
Fontenay, M. Mutations of IDH1 and IDH2 genes in early and accelerated phases of
myelodysplastic syndromes and MDS/myeloproliferative neoplasms. Leukemia. 2010;24:10941096.
30. Lagarde,A., Rouleau, E., Ferrari, A., Noguchi, T., Qiu, J., Briaux, A., Bourdon, V., Remy, V.,
Gaildrat, P., Adelaide, J., Birnbaum, D., Lidereau, R., Sobol, H., and Olschwang, S. Germline APC
mutation spectrum derived from 863 genomic variations identified through a 15-year medical
genetics service to French patients with FAP. Journal of Medical Genetics. 2010;47:721-722.
31. Lenfant,N., Polanowska, J., Bamps, S., Omi, S., Borg, J. P., and Reboul, J. A genome-wide
study of PDZ-domain interactions in C. elegans reveals a high frequency of non-canonical binding.
BMC Genomics. 2010;11:67132. Lugari,A., Betzi, S., Decroly, E., Bonnaud, E., Hermant, A., Guillemot, J. C., Debarnot, C.,
Borg, J. P., Bouvet, M., Canard, B., Morelli, X., and Lecine, P. Molecular mapping of the RNA Cap
2'-O-methyltransferase activation interface between SARS coronavirus nsp10 and nsp16. Journal of
33. Paul,C., Sans, B., Suarez, F., Casassus, P., Barete, S., Lanternier, F., Grandpeix-Guyodo, C.,
Dubreuil, P., Palmerini, F., Mansfield, C. D., Gineste, P., Moussy, A., Hermine, O., and Lortholary,
O. Masitinib for the treatment of systemic and cutaneous mastocytosis with handicap: A phase 2a
study. American Journal of Hematology. 2010;85:921-925.
34. Pierard,V., Guiguen, A., Colin, L., Wijmeersch, G., Vanhulle, C., Van Driessche, B., Dekoninck,
A., Blazkova, J., Cardona, C., Merimi, M., Vierendeel, V., Calomme, C., Nguyen, T. L., Nuttinck, M.,
Twizere, J. C., Kettmann, R., Portetelle, D., Burny, A., Hirsch, I., Rohr, O., and Van Lint, C. DNA
cytosine methylation in the bovine leukemia virus promoter is associated with latency in a
lymphoma-derived B-cell line: Potential involvement of direct inhibition of CREB/CREM/ATF
transcription factor binding. Journal of Biological Chemistry. 2010;285:19434-19449.
35. Prebet,T., Lhoumeau, A. C., Arnoulet, C., Aulas, A., Marchetto, S., Audebert, S., Puppo, F.,
Chabannon, C., Sainty, D., Santoni, M. J., Sebbagh, M., Summerour, V., Huon, Y., Shin, W. S.,
Lee, S. T., Esterni, B., Vey, N., and Borg, J. P. The cell polarity PTK7 receptor acts as a modulator
of the chemotherapeutic response in acute myeloid leukaemia and impairs clinical outcome. Blood.
2010;116:2315-2323.
Unité de Recherche. Centre de Recherche en Cancérologie de Marseille
15/23
36. Reynolds,L.E., Watson, A. R., Baker, M., Jones, T. A., D'Amico, G., Robinson, S. D., Joffre, C.,
Garrido-Urbani, S., Rodriguez-Manzaneque, J. C., Martino-Echarri, E., Aurrand-Lions, M., Sheer,
D., Dagna-Bricarelli, F., Nizetic, D., McCabe, C. J., Turnell, A. S., Kermorgant, S., Imhof, B. A.,
Adams, R., Fisher, E. M., Tybulewicz, V. L., Hart, I. R., and Hodivala-Dilke, K. M. Tumour
angiogenesis is reduced in the Tc1 mouse model of Down's syndrome. Nature. 2010;465:813-817.
37. Rocquain,J., Gelsi-Boyer, V., Adelaide, J., Murati, A., Carbuccia, N., Vey, N., Birnbaum, D.,
Mozziconacci, M. J., and Chaffanet, M. Alteration of cohesin genes in myeloid diseases. American
Journal of Hematology. 2010;85:717-719.
38. Rocquain,J., Carbuccia, N., Trouplin, V., Raynaud, S., Murati, A., Nezri, M., Tadrist, Z.,
Olschwang, S., Vey, N., Birnbaum, D., Gelsi-Boyer, V., and Mozziconacci, M. J. Combined
mutations of ASXL1, CBL, FLT3, IDH1, IDH2, JAK2, KRAS, NPM1, NRAS, RUNX1, TET2 and WT1
genes in myelodysplastic syndromes and acute myeloid leukemias. BMC Cancer. 2010;10:40139. Sabatier,R., Bouvier, C., de Pinieux, G., Sarran, A., Brenot-Rossi, I., Pedeutour, F., Chetaille,
B., Viens, P., Weiller, P. J., and Bertucci, F. Low-grade extraskeletal osteosarcoma of the chest
wall: case report and review of literature. BMC Cancer. 2010;10:64540. Sabatier,R., Finetti, P., Cervera, N., Birnbaum, D., and Bertucci, F. DNA microarrays and
prediction of clinical outcome in ovarian carcinoma patients. Bulletin du Cancer. 2010;97:979-989.
41. Sabatier,R., Adelaide, J., Finetti, P., Ferrari, A., Huiart, L., Sobol, H., Chaffanet, M., Birnbaum,
D., and Bertucci, F. BARD1 homozygous deletion, a possible alternative to BRCA1 mutation in basal
breast cancer. Genes, Chromosomes and Cancer. 2010;49:1143-1151.
42. Salmi-Smail,C., Fabre, A., Dequiedt, F., Restouin, A., Castellano, R., Garbit, S., Roche, P.,
Morelli, X., Brunel, J. M., and Collette, Y. Modified cap group suberoylanilide hydroxamic acid
histone deacetylase inhibitor derivatives reveal improved selective antileukemic activity. Journal of
Medicinal Chemistry. 2010;53:3038-3047.
43. Sedjai,F., Acquaviva, C., Chevrier, V., Chauvin, J. P., Coppin, E., Aouane, A., Coulier, F., Tolun,
A., Pierres, M., Birnbaum, D., and Rosnet, O. Control of ciliogenesis by FOR20, a novel centrosome
and pericentriolar satellite protein. Journal of Cell Science. 2010;123:2391-2401
44. Serriari,N.E., Gondois-Rey, F., Guillaume, Y., Remmerswaal, E. B., Pastor, S., Messal, N.,
Truneh, A., Hirsch, I., van Lier, R. A., and Olive, D. B and T Lymphocyte Attenuator Is Highly
Expressed on CMV-Specific T Cells during Infection and Regulates Their Function. Journal of
Immunology. 2010;185:3140-3148.
45. Shi,X., Opi, S., Lugari, A., Restouin, A., Coursindel, T., Parrot, I., Perez, J., Madore, E.,
Zimmermann, P., Corbeil, J., Huang, M., Arold, S. T., Collette, Y., and Morelli, X. Identification and
biophysical assessment of the molecular recognition mechanisms between the human haemopoietic
cell kinase Src homology domain 3 and ALG-2-interacting protein X. Biochemical Journal.
2010;431:93-102.
46. Sircoulomb,F., Bekhouche, I., Finetti, P., Adelaide, J., Ben Hamida, A., Bonansea, J., Raynaud,
S., Innocenti, C., Charafe-Jauffret, E., Tarpin, C., Ben Ayed, F., Viens, P., Jacquemier, J., Bertucci,
F., Birnbaum, D., and Chaffanet, M. Genome profiling of ERBB2-amplified breast cancers. BMC
Cancer. 2010;10:53947. Sokol,H., Georgin-Lavialle, S., Grandpeix-Guyodo, C., Canioni, D., Barete, S., Dubreuil, P.,
Lortholary, O., Beaugerie, L., and Hermine, O. Gastrointestinal involvement and manifestations in
systemic mastocytosis. Inflammatory Bowel Diseases. 2010;16:1247-1253.
48. Taieb,D., Giusiano, S., Sebag, F., Marcy, M., De Micco, C., Palazzo, F. F., Dusetti, N. J.,
Iovanna, J. L., Henry, J. F., Garcia, S., and Taranger-Charpin, C. Tumor protein p53-induced
nuclear protein (TP53INP1) expression in medullary thyroid carcinoma: a molecular guide to the
optimal extent of surgery? World Journal of Surgery. 2010;34:830-835.
49. Tenan,M., Aurrand-Lions, M., Widmer, V., Alimenti, A., Burkhardt, K., Lazeyras, F., Belkouch,
M. C., Hammel, P., Walker, P. R., Duchosal, M. A., Imhof, B. A., and Dietrich, P. Y. Cooperative
expression of junctional adhesion molecule-C and -B supports growth and invasion of glioma. Glia.
2010;58:524-537.
Unité de Recherche. Centre de Recherche en Cancérologie de Marseille
16/23
50. Voisset,E., Lopez, S., Chaix, A., Georges, C., Hanssens, K., Prebet, T., Dubreuil, P., and De
Sepulveda, P. FES kinases are required for oncogenic FLT3 signaling. Leukemia. 2010;24:721-728.
51. Voisset,E., Lopez, S., Chaix, A., Vita, M., George, C., Dubreuil, P., and De Sepulveda, P. FES
kinase participates in KIT-ligand induced chemotaxis. Biochemical and Biophysical Research
Communications. 2010;393:174-178.
52. Yang,Y., Letard, S., Borge, L., Chaix, A., Hanssens, K., Lopez, S., Vita, M., Finetti, P.,
Birnbaum, D., Bertucci, F., Gomez, S., De Sepulveda, P., and Dubreuil, P. Pediatric mastocytosisassociated KIT extracellular domain mutations exhibit different functional and signaling properties
compared with KIT-phosphotransferase domain mutations. Blood. 2010;116:1114-1123.
53. Zaoui,K., Benseddik, K., Daou, P., Salaun, D., and Badache, A. ErbB2 receptor controls
microtubule capture by recruiting ACF7 to the plasma membrane of migrating cells. Proceedings of
the National Academy of Sciences of the United States of America. 2010;107:18517-18522.
54. Arcangeli,M.L., Frontera, V., Bardin, F., Obrados, E., Adams, S., Chabannon, C., Schiff, C.,
Mancini, S. J., Adams, R. H., and Aurrand-Lions, M. JAM-B regulates maintenance of hematopoietic
stem cells in the bone marrow. Blood. 2011;118:4609-4619.
55. Baron Gaillard,C.L., Pallesi-Pocachard, E., Massey-Harroche, D., Richard, F., Arsanto, J. P.,
Chauvin, J. P., Lecine, P., Kramer, H., Borg, J. P., and Le Bivic, A. Hook2 is involved in the
morphogenesis of the primary cilium. Molecular Biology of the Cell. 2011;22:4549-4562.
56. Bekhouche,I., Finetti, P., Adelaide, J., Ferrari, A., Tarpin, C., Charafe-Jauffret, E., Charpin, C.,
Houvenaeghel, G., Jacquemier, J., Bidaut, G., Birnbaum, D., Viens, P., Chaffanet, M., and Bertucci,
F. High-resolution comparative genomic hybridization of inflammatory breast cancer and
identification of candidate genes. PLoS ONE. 2011;6:e1695057. Bertucci,F., Borie, N., Roche, H., Bachelot, T., Le Doussal, J. M., MacGrogan, G., Debono, S.,
Martinec, A., Treilleux, I., Finetti, P., Esterni, B., Extra, J. M., Geneve, J., Hermitte, F., Chabannon,
C., Jacquemier, J., Martin, A. L., Longy, M., Maraninchi, D., Fert, V., Birnbaum, D., and Viens, P.
Gene expression profile predicts outcome after anthracycline-based adjuvant chemotherapy in
early breast cancer. Breast Cancer Research and Treatment. 2011;127:363-373.
58. Birnbaum,D.J., Birnbaum, D., and Bertucci, F. Endometriosis-associated ovarian carcinomas.
New England Journal of Medicine. 2011;364:482-485.
59. Birnbaum,D.J., Adelaide, J., Mamessier, E., Finetti, P., Lagarde, A., Monges, G., Viret, F.,
Goncalves, A., Turrini, O., Delpero, J. R., Iovanna, J., Giovannini, M., Birnbaum, D., and Chaffanet,
M. Genome profiling of pancreatic adenocarcinoma. Genes, Chromosomes and Cancer.
2011;50:456-465.
60. Bozzano,F., Picciotto, A., Costa, P., Marras, F., Fazio, V., Hirsch, I., Olive, D., Moretta, L., and
De Maria, A. Activating NK cell receptor expression/function (NKp30,NKp46,DNAM-1) during
chronic viraemic HCV infection is associated with the outcome of combined treatment. European
Journal of Immunology. 2011;41:2905-2914.
61. Brecqueville,M., Cervera, N., Rey, J., Adelaide, J., Carbuccia, N., Chaffanet, M., Mozziconacci,
M. J., Vey, N., Birnbaum, D., Gelsi-Boyer, V., and Murati, A. Mutations and deletions of the SUZ12
polycomb gene in myeloproliferative neoplasms. Blood Cancer Journal. 2011;1:e3362. Brecqueville,M., Cervera, N., Gelsi-Boyer, V., Murati, A., Adelaide, J., Chaffanet, M., Rey, J.,
Vey, N., Mozziconacci, M. J., and Birnbaum, D. Rare mutations in DNMT3A in myeloproliferative
neoplasms and myelodysplastic syndromes. Blood Cancer Journal. 2011;1:e1863. Cadot,P., Hensel, P., Bensignor, E., Hadjaje, C., Marignac, G., Beco, L., Fontaine, J., Jamet, J.
F., Georgescu, G., Campbell, K., Cannon, A., Osborn, S. C., Messinger, L., Gogny-Goubert, M.,
Dubreuil, P., Moussy, A., and Hermine, O. Masitinib decreases signs of canine atopic dermatitis: a
multicentre, randomized, double-blind, placebo-controlled phase 3 trial. Veterinary Dermatology.
2011;22:554-564.
Unité de Recherche. Centre de Recherche en Cancérologie de Marseille
17/23
64. Carcopino,X., Bolger, N., Henry, M., Mancini, J., Boubli, L., Olive, D., Cleary, S., Prendiville, W.,
and Tamalet, C. Evaluation of type-specific HPV persistence and high-risk HPV viral load
quantitation in HPV positive women under 30 with normal cervical cytology. Journal of Medical
Virology. 2011;83:637-643.
65. Chaib,H., Prebet, T., Vey, N., and Collette, Y. Histone méthyltransférases:Une nouvelle classe
de cibles thérapeutiques dans le traitement du cancer ? M/S Medecine Sciences. 2011;27:725-732.
66. Chaix,A., Lopez, S., Voisset, E., Gros, L., Dubreuil, P., and De Sepulveda, P. Mechanisms of
STAT proteins activation by oncogenic kit mutants in neoplastic mast cells. Journal of Biological
Chemistry. 2011;286:5956-5966.
67. Feracci,M., Pimentel, C., Bornet, O., Roche, P., Salaun, D., Badache, A., and Guerlesquin, F.
MEMO associated with an ErbB2 receptor phosphopeptide reveals a new phosphotyrosine motif.
FEBS Letters. 2011;585:2688-2692.
68. Fournier,G., Cabaud, O., Josselin, E., Chaix, A., Adelaide, J., Isnardon, D., Restouin, A.,
Castellano, R., Dubreuil, P., Chaffanet, M., Birnbaum, D., and Lopez, M. Loss of AF6/afadin, a
marker of poor outcome in breast cancer, induces cell migration, invasiveness and tumor growth.
Oncogene. 2011;30:3862-3874.
69. Franceschi,C., Collignon, A., Isnardon, D., Benkoel, L., Verine, A., Silvy, F., Bernard, J. P.,
Lombardo, D., Beraud, E., Olive, D., and Mas, E. A novel tumor-associated pancreatic glycoprotein
is internalized by human dendritic cells and induces their maturation. Journal of Immunology.
2011;186:4067-4077.
70. Frontera,V., Arcangeli, M. L., Zimmerli, C., Bardin, F., Obrados, E., Audebert, S., Bajenoff, M.,
Borg, J. P., and Aurrand-Lions, M. Cutting Edge: JAM-C Controls Homeostatic Chemokine Secretion
in Lymph Node Fibroblastic Reticular Cells Expressing Thrombomodulin. Journal of Immunology.
2011;187:603-607.
71. Georgescu,S.P., Aronovitz, M. J., Iovanna, J. L., Patten, R. D., Kyriakis, J. M., and Goruppi, S.
Decreased metalloprotease 9 induction, cardiac fibrosis, and higher autophagy after pressure
overload in mice lacking the transcriptional regulator p8. American Journal of Physiology-Cell
Physiology. 2011;301:C1046-C1056.
72. Georgin-Lavialle,S., Lhermitte, L., Baude, C., Barete, S., Bruneau, J., Launay, J. M.,
Chandesris, M. O., Hanssens, K., de Gennes, C., Damaj, G., Lanternier, F., Hamidou, M.,
Lortholary, O., Dubreuil, P., Feger, F., Lepelletier, Y., and Hermine, O. Blood CD34-c-Kit+ cell rate
correlates with aggressive forms of systemic mastocytosis and behaves like a mast cell precursor.
Blood. 2011;118:5246-5249.
73. Ginestier,C., Sircoulomb, F., Charafe-Jauffret, E., Chaffanet, M., and Birnbaum, D. ZNF703: un
nouvel oncogène du cancer du sein. M/S Medecine Sciences. 2011;27:357-359.
74. Ginestier,C., Charafe-Jauffret, E., and Birnbaum, D. Breast tumor microenvironment: In the
eye of the cytokine storm. Cell Cycle. 2011;10:2420-2421.
75. Goncalves,A., Finetti, P., Sabatier, R., Gilabert, M., Adelaide, J., Borg, J. P., Chaffanet, M.,
Viens, P., Birnbaum, D., and Bertucci, F. Poly(ADP-ribose) polymerase-1 mRNA expression in
human breast cancer: a meta-analysis. Breast Cancer Research and Treatment. 2011;127:273281.
76. Jacquemier,J., Boher, J. M., Roche, H., Esterni, B., Serin, D., Kerbrat, P., Andre, F., Finetti, P.,
Charafe-Jauffret, E., Martin, A. L., Campone, M., Viens, P., Birnbaum, D., Penault-Llorca, F., and
Bertucci, F. Protein expression, survival and docetaxel benefit in node-positive breast cancer
treated with adjuvant chemotherapy in the FNC. Breast Cancer Research. 2011;13:R10977. Letessier,A., Birnbaum, D., Debatisse, M., and Chaffanet, M. La pauvreté en sites d'initiation de
la réplication rend-elle fragile certaines régions du génome ? M/S Medecine Sciences.
2011;27:707-709.
Unité de Recherche. Centre de Recherche en Cancérologie de Marseille
18/23
78. Lhoumeau,A.C., Puppo, F., Prebet, T., Kodjabachian, L., and Borg, J. P. PTK7: A cell polarity
receptor with multiple facets. Cell Cycle. 2011;10:1233-1236.
79. Lugari,A., Breuer, S., Coursindel, T., Opi, S., Restouin, A., Shi, X., Nazabal, A., Torbett, B. E.,
Martinez, J., Collette, Y., Parrot, I., Arold, S. T., and Morelli, X. A specific protein disorder catalyzer
of HIV-1 Nef. Bioorganic and Medicinal Chemistry. 2011;19:7401-7406.
80. Maddugoda,M.P., Stefani, C., Gonzalez-Rodriguez, D., Saarikangas, J., Torrino, S., Janel, S.,
Munro, P., Doye, A., Prodon, F., Aurrand-Lions, M., Goossens, P. L., Lafont, F., Bassereau, P.,
Lappalainen, P., Brochard, F., and Lemichez, E. cAMP Signaling by Anthrax Edema Toxin Induces
Transendothelial Cell Tunnels, which Are Resealed by MIM via Arp2/3-Driven Actin Polymerization.
Cell Host Microbe. 2011;10:464-474.
81. Mamessier,E., Sylvain, A., Thibult, M. L., Houvenaeghel, G., Jacquemier, J., Castellano, R.,
Goncalves, A., Andre, P., Romagne, F., Thibault, G., Viens, P., Birnbaum, D., Bertucci, F., Moretta,
A., and Olive, D. Human breast cancer cells enhance self tolerance by promoting evasion from NK
cell antitumor immunity. Journal of Clinical Investigation. 2011;121:3609-3622.
82. Mamessier,E., Sylvain, A., Bertucci, F., Castellano, R., Finetti, P., Houvenaeghel, G., CharaffeJaufret, E., Birnbaum, D., Moretta, A., and Olive, D. Human breast tumor cells induce selftolerance mechanisms to avoid NKG2D-mediated and DNAM-mediated NK-cells recognition. Cancer
Research. 2011;71:6621-6632.
83. Messal,N., Mamessier, E., Sylvain, A., Celis-Gutierrez, J., Thibult, M. L., Chetaille, B., Firaguay,
G., Pastor, S., Guillaume, Y., Wang, Q., Hirsch, I., Nunes, J. A., and Olive, D. Differential role for
CD277 as co-regulator of the immune signal in T and NK cells. European Journal of Immunology.
2011;41:3443-3454.
84. Messal,N., Serriari, N. E., Pastor, S., Nunes, J. A., and Olive, D. PD-L2 is expressed on
activated human T cells and regulates their function. Molecular Immunology. 2011;48:2214-2219.
85. Olive,D., le Thi, S., Xerri, L., Hirsch, I., and Nunes, J. A. Rôle de CTLA-4 dans la cosignalisation
négative du système immunitaire. M/S Medecine Sciences. 2011;27:842-849
86. Piette,F., Belmin, J., Vincent, H., Schmidt, N., Pariel, S., Verny, M., Marquis, C., Mely, J.,
Hugonot-Diener, L., Kinet, J. P., Dubreuil, P., Moussy, A., and Hermine, O. Masitinib as an adjunct
therapy for mild-to-moderate Alzheimer's disease: a randomised, placebo-controlled phase 2 trial.
Alzheimer's Research and Therapy. 2011;3:1687. Prebet,T., Etienne, A., Devillier, R., Romeo, E., Charbonnier, A., D'incan, E., Esterni, B.,
Arnoulet, C., Blaise, D., and Vey, N. Improved outcome of patients with low- and intermediate-risk
cytogenetics acute myeloid leukemia (AML) in first relapse with gemtuzumab and cytarabine versus
cytarabine: results of a retrospective comparative study. Cancer. 2011;117:974-981.
88. Prebet,T., Gore, S. D., Esterni, B., Gardin, C., Itzykson, R., Thepot, S., Dreyfus, F., Rauzy, O.
B., Recher, C., Ades, L., Quesnel, B., Beach, C. L., Fenaux, P., and Vey, N. Outcome of high-risk
myelodysplastic syndrome after azacitidine treatment failure. Journal of Clinical Oncology.
2011;29:3322-3327.
89. Prebet,T. and Vey, N. Vorinostat in acute myeloid leukemia and myelodysplastic syndromes.
Expert Opinion on Investigational Drugs. 2011;20:287-295.
90. Puppo,F., Thome, V., Lhoumeau, A. C., Cibois, M., Gangar, A., Lembo, F., Belotti, E.,
Marchetto, S., Lecine, P., Prebet, T., Sebbagh, M., Shin, W. S., Lee, S. T., Kodjabachian, L., and
Borg, J. P. Protein tyrosine kinase 7 has a conserved role in Wnt/beta-catenin canonical signalling.
EMBO Report. 2011;12:43-49.
91. Qiu,J., Hutter, P., Rahner, N., Patton, S., and Olschwang, S. The educational role of external
quality assessment in genetic testing: a 7-year experience of The European Molecular Genetics
Quality Network (EMQN) in Lynch syndrome. Human Mutation. 2011;32:696-697.
Unité de Recherche. Centre de Recherche en Cancérologie de Marseille
19/23
92. Qiu,J., Compagnone, M., Laibe, S., Lagarde, A., Goncalves, A., Turrini, O., Xerri, L., Monges,
G., and Olschwang, S. BRAF p.Val600Glu (V600E) somatic mutation is mainly associated with MSS
phenotype in metastatic colorectal cancer. Cancer Genomics and Proteomics. 2011;8:15-18.
93. Sabatier,R., Finetti, P., Mamessier, E., Raynaud, S., Cervera, N., Lambaudie, E., Jacquemier,
J., Viens, P., Birnbaum, D., and Bertucci, F. Kinome expression profiling and prognosis of basal
breast cancers. Molecular Cancer. 2011;10:86-86.
94. Sabatier,R., Finetti, P., Adelaide, J., Guille, A., Borg, J. P., Chaffanet, M., Lane, L., Birnbaum,
D., and Bertucci, F. Down-regulation of ECRG4, a candidate tumor suppressor gene, in human
breast cancer. PLoS ONE. 2011;6:e2765695. Sabatier,R., Finetti, P., Bonensea, J., Jacquemier, J., Adelaide, J., Lambaudie, E., Viens, P.,
Birnbaum, D., and Bertucci, F. A seven-gene prognostic model for platinum-treated ovarian
carcinomas. British Journal of Cancer. 2011;105:304-311.
96. Sabatier,R., Jacquemier, J., Bertucci, F., Esterni, B., Finetti, P., Azario, F., Birnbaum, D., Viens,
P., Goncalves, A., and Extra, J. M. Peritumoural vascular invasion: A major determinant of triplenegative breast cancer outcome. European Journal of Cancer. 2011;47:1537-1545.
97. Sabatier,R., Finetti, P., Cervera, N., Tallet, A., Benchalal, M., Houvenaeghel, G., Jacquemier, J.,
Birnbaum, D., and Bertucci, F. Gene Expression Profiling and its Utility in Prediction of Local
Relapse after Breast-conserving Therapy in Early Breast Cancer. Cancer Genomics and Proteomics.
2011;8:199-209.
98. Sanchez,C.J., Le Treut T., Boehrer, A., Knoblauch, B., Imbert, J., Olive, D., and Costello, R. T.
Natural killer cells and malignant haemopathies: a model for the interaction of cancer with innate
immunity. Cancer Immunology, Immunotherapy. 2011;60:1-13.
99. Sebbagh,M., Olschwang, S., Santoni, M. J., and Borg, J. P. The LKB1 complex-AMPK pathway:
the tree that hides the forest. Familial Cancer. 2011;10:415-424.
100. Sircoulomb,F., Nicolas, N., Ferrari, A., Finetti, P., Bekhouche, I., Rousselet, E., Lonigro, A.,
Adelaide, J., Baudelet, E., Esteyries, S., Wicinski, J., Audebert, S., Charafe-Jauffret, E.,
Jacquemier, J., Lopez, M., Borg, J. P., Sotiriou, C., Popovici, C., Bertucci, F., Birnbaum, D.,
Chaffanet, M., and Ginestier, C. ZNF703 gene amplification at 8p12 specifies luminal B breast
cancer. EMBO Molecular Medicine. 2011;3:153-166.
101. Spicuglia,S., Vincent-Fabert, C., Benoukraf, T., Tiberi, G., Saurin, A. J., Zacarias-Cabeza, J.,
Grimwade, D., Mills, K., Calmels, B., Bertucci, F., Sieweke, M., Ferrier, P., and Duprez, E.
Characterisation of Genome-Wide PLZF/RARA Target Genes. PLoS ONE. 2011;6:e24176102. Trejbalova,K., Blazkova, J., Matouskova, M., Kucerova, D., Pecnova, L., Vernerova, Z.,
Heracek, J., Hirsch, I., and Hejnar, J. Epigenetic regulation of transcription and splicing of
syncytins, fusogenic glycoproteins of retroviral origin. Nucleic Acids Research. 2011;39:8728-8739.
103. Zhao,X.W., van Beek, E. M., Schornagel, K., Van der Maaden, H., Van Houdt, M., Otten, M.
A., Finetti, P., Van Egmond, M., Matozaki, T., Kraal, G., Birnbaum, D., van Elsas, A., Kuijpers, T.
W., Bertucci, F., and van den Berg, T. K. CD47-signal regulatory protein-alpha (SIRPalpha)
interactions form a barrier for antibody-mediated tumor cell destruction. Proceedings of the
National Academy of Sciences of the United States of America. 2011;108:18342-18347.
104. Gillibert-Duplantier J, Duthey B, Sisirak V, Salaün D, Gargi T, Trédan O, Finetti P, Bertucci F,
Birnbaum D, Bendriss-Vermare N, Badache A. Gene expression profiling identifies sST2 as an
effector of ErbB2-driven breast carcinoma cell motility, associated with metastasis. Oncogene.
2011 Nov 21. doi: 10.1038/onc.2011.525.
Unité de Recherche. Centre de Recherche en Cancérologie de Marseille
20/23
CONTRATS ANNÉES 2010 et 2011
Nom projet
Pscientifique
EQUIPE LABEL LIGUE
D BIRNBAUM
Date Début
Projet
11/03/2010
EQUIPE LABELLISEE LIGUE
JP BORG
11/03/2010
31/12/2012
LIGUE
S OLSCHWANG
08/04/2010
07/04/2014
EQUIPE LABEL LIGUE
P DUBREUIL
01/01/2011
31/12/2013
ARC LIBRE
S OLSCHWANG
11/12/2008
30/06/2012
ARC FIXE
D BIRNBAUM
23/06/2009
22/06/2011
ARC FIXE
Y COLLETTE
10/12/2009
31/12/2011
ARC FIXE
M AURRAND-LIONS
10/12/2009
31/12/2010
ARC FIXE
D BIRNBAUM
10/12/2009
31/12/2010
ARC FIXE
E DUPREZ
10/12/2009
31/12/2011
ARC FIXE
A BADACHE
10/08/2010
30/06/2011
ARC
S OLSCHWANG
14/10/2010
30/06/2012
ARC FIXE
A BADACHE
01/01/2011
30/12/2012
ARC LIBRE
D OLIVE
21/09/2011
30/06/2014
FRM
JP BORG
28/09/2009
27/09/2010
FRM Installation
E DUPREZ
12/05/2010
11/11/2010
FDF
E CHARAFFE
15/12/2010
31/12/2013
ASS_L_FUGAIN_DUPREZ
E DUPREZ
13/11/2009
30/06/2012
ANRS
I HIRSCH
01/06/2009
31/05/2011
ANRS
I HIRSCH
01/09/2010
31/08/2012
ANRS
D OLIVE
01/03/2011
28/02/2012
CR PACA
D BIRNBAUM
28/06/2010
30/06/2014
OSEO
P DUBREUIL
12/02/2009
11/02/2013
INCA PL
P DUBREUIL
14/12/2007
13/02/2012
INCA PL
D OLIVE
14/12/2007
11/02/2011
INCA PL
M LOPEZ
14/12/2007
30/11/2010
INCA PL
D OLIVE
14/12/2007
30/11/2010
Procan AXE III
Y COLLETTE
28/01/2008
31/10/2011
Procan AXE III
JP BORG
28/01/2008
31/10/2011
Date Fin Projet
31/12/2012
INCA
G BIDAUT
24/01/2008
23/03/2013
Procan AXE II
MJ MOZZICONACCI
28/01/2008
31/08/2011
Procan AXE II
D BIRNBAUM
28/01/2008
31/08/2011
PROCAN AXE IV
D OLIVE
28/01/2008
31/08/2011
INCA PL
D BIRNBAUM
17/10/2008
31/08/2012
CANCEROPOLE
D BIRNBAUM
16/11/2008
15/11/2011
INCA
D BIRNBAUM
29/09/2009
08/04/2013
CANCEROPOLE
P DUBREUIL
27/09/2009
26/09/2012
CANCEROPOLE
D OLIVE
28/10/2009
13/11/2013
INCA
D OLIVE
24/09/2010
23/09/2013
INCA
D OLIVE
07/10/2010
30/10/2013
INCA
D BIRNBAUM
10/12/2010
09/12/2013
ANR
JP BORG
03/02/2009
02/02/2012
ANR
L CAMOIN
01/01/2009
30/06/2012
Unité de Recherche. Centre de Recherche en Cancérologie de Marseille
21/23
ANR
JP BORG
01/10/2009
30/03/2013
SERVIER
D BIRNBAUM
01/01/2010
31/12/2010
THESES de DOCTORAT ANNÉES 2010 et 2011
Nom et Prénom du
Doctorant
Equipe
Titre de la Thèse
Date de
soutenance
GUITTARD Geoffrey
OLIVE
Signalisation lymphocytaire T : identification
d'un nouveau médiateur lipidique, le
phosphatidylinositol 5-phosphate (Ptdlns5P)
17/02/2010
STUHL Laetitia
DUBREUIL
Role de Naca et de ses partenaires
moléculaires dans la différenciation
erythroide normale et pathologique des
syndromes myélodysplasiques
30/03/2010
LENFANT Nicolas
REBOUL
L'interactome des domaines PDZ de
Caenorhabditis elegans
08/06/2010
CHETAILLE Bruno
OLIVE
Facteurs pronostiques biopathologiques des
lymphomes Hodgkiniens: influence du
microenvironnement
18/06/2010
BIRNBAUM
L’afadine est un marqueur de mauvais
pronostic des carcinomes mammaires
impliqué dans la croissance tumorale et la
migration cellulaire
25/06/2010
CHAIX Amandine
DUBREUIL
Les spécificités de la signalisation
oncogénique par rapport à la signalisation
physiologique : le modèle de KIT, un
récepteur à activité tyrosine kinase
30/09/2010
ROCQUAIN Julien
BIRNBAUM
Recherche de nouvelles cibles moléculaires
dans les syndromes myélodysplasiques et
leucémies aiguës myéloïdes
29/11/2010
BELOTTI Edwige
BORG
Caractérisation du récepteur de la polarité
planaire Vangl2 dans les cancers du sein
21/12/2010
MESSAL Nassima
OLIVE
Expression, régulation et caractérisation
fonctionnelle des molécules de cosignalisation immunitaire, PD-L2 et CD277
dans l’activation lymphocytaire T
20/01/2011
DENTAL Clélia
OLIVE
Effet du Virus de l'Hépatite C sur les cellules
plasmacytoïdes dendritiques
04/03/2011
CHAIB Hassiba
OLIVE
FOURNIER Gaëlle
Unité de Recherche. Centre de Recherche en Cancérologie de Marseille
22/23
Etude d'une nouvelle protéine centrosomale
impliquée dans la ciliogenèse, FOR20
13/05/2011
OLIVE
PD-1 et BTLA au coeur des lymphocytes B :
du physiologique aux lymphomes
05/10/2011
KADRA Gais
BORG
Prédiction de l'activitè anti-tumoral de
Docetaxel, Paclitaxel et Ixabepilone dans le
cancer du sein : analyse de profilage
d'expression génétique
10/10/2011
FRONTERA Vincent
AURRAND-LIONS
Caractérisation fonctionnelle des molécules
d’adhésion jonctionnelle (JAM) dans
l’environnement ganglionnaire et médullaire
06/12/2011
VEUILLEN Caroline
OLIVE
Caractérisation des mécanismes
d'échappement tumoral à la lyse NK dans la
LLC-B et le cancer de la prostate
15/11/2011
SEDJAI Fatima
BIRNBAUM
GHIDOUCHE Abderrezak
BIRNBAUM
THIBULT Marie-Laure
ACCUEIL MASTERS
Bioinformatique, Biologie structurale et génomique - Aix-Marseille
Développement et Immunologie - Aix-Marseille
Pathologie Humaine : Oncologie : pharmacologie et thérapeutique - Aix-Marseille
EQUIPEMENTS MAJEURS
Trieurs
Microscopes
Animalerie
Unité de Recherche. Centre de Recherche en Cancérologie de Marseille
23/23