UNITÉ DE RECHERCHE Centre de Recherche en Cancérologie de
Transcription
UNITÉ DE RECHERCHE Centre de Recherche en Cancérologie de
UNITÉ DE RECHERCHE Centre de Recherche en Cancérologie de Marseille DIRECTEUR : BORG Jean-Paul ADRESSE : Institut Paoli Calmettes 27 Bd Lei Roure BP 30059 13273 Marseille cedex 09 TELEPHONE : 04 86 97 72 00 COURRIEL : [email protected] RATTACHEMENTS : AMU INSERM CNRS IPC POLES HOSPITALIERS : 3 - Imagerie Médicale (Intersites) 5 - Anapath-Digestif-Onco-Uro-Endocrinologie (Nord) ECOLE DOCTORALE : Sciences de la Vie et de la Santé (ED 062) DISCIPLINES D’APPARTENANCES : DS 5 - Biologie, médecine, santé SPECIALITÉS : Oncologie/Immunologie GESTIONNAIRES DE L’UNITÉ : DUVIVIER Laurence EFFECTIFS Enseignants-Chercheurs : 14 Chercheurs EPST : 49 Autres Chercheurs : 36 IATOS/ITA : 66 Autres IATOS/ITA : 23 Doctorants : 54 Unité de Recherche. Centre de Recherche en Cancérologie de Marseille 1/23 PERSONNELS IMPLIQUÉS DANS LA RECHERCHE Nom Acquaviva Acquaviva Acunzo Adélaïde Afrache Agnelli Andrieu Aouar Aragnol Arbiol Arnoulet Audebert Audry Aurrand-Lions Baccini Badache Bailly Bapin Barbarat Bardin Baron-Gaillard Barthet Basse Baty Baudelet Baylot Benseddik Benyamine Bernard Berthezene Bertucci Betzi Bidaut Birg Prénom Laurent Claire Julie José Hassnae Lauren Claudia Besma Denise Christine Christine Stéphane Julien Michel Michel Ali Éric Luc Bernadette Florence Carole Marc Marie jeanne Daniel Émilie Virginie Khedidja Audrey Stéphanie Patrice François Stéphane Ghislain Françoise statut CR1 thèse postdoc Tech IPC thèse IE INSERM thèse thèse PU AI INSERM PH IR INSERM thèse CR1 TCN INSERM DR2 CR1 TCN INSERM THQ IPC AI INSERM postdoc PU PH AI INSERM DR AI INSERM thèse thèse thèse IE INSERM IEH INSERM PUPH postdoc IR2 INSERM DR1 Birnbaum Blaise Bodin Bonacci Borg Borge Bourdely Bourgeas Boutchama Brecqueville Brisson Brunel Cabaud Calmels Camoin Carbuccia Carrier Daniel Didier Jérome Thomas Jean-Paul Laurence Pierre Raphaël Henri Mandy Lydie Jean michel Olivier Boris Luc Nadine Alice DR MD – PU-PH IE INSERM Thèse PU PH AI INSERM thèse thèse TCN INSERM Thèse Thèse CR1 IE INSERM PH IR INSERM AI INSERM CR Téléphone 04 91 16 43 04 86 97 72 04 86 97 72 04 91 22 33 04 86 97 73 04 91 82 88 04 86 97 72 04 86 97 72 04 91 16 43 04 91 16 43 04 91 22 33 04 91 22 33 04 91 16 45 04 86 97 72 04 86 97 72 04 86 97 73 04 86 97 72 04 86 97 73 04 86 97 73 04 86 97 72 04 86 97 73 04 91 82 88 04 91 16 45 04 91 82 88 04 91 22 33 04 86 97 72 04 04 04 04 04 04 04 04 54 04 04 04 04 04 66 62 66 04 41 35 66 72 66 21 76 07 ou 33 39 37 91 08 21 57 61 46 92 52 03 06 23 07 66 86 91 91 91 86 86 86 86 97 16 82 22 97 97 97 97 72 45 88 33 73 73 72 72 76 86 26 33 et poste 4779 33 01 06 61 ou 04 91 22 33 91 91 91 86 91 22 16 82 97 82 36 45 88 72 88 44 86 06 51 16 04 91 16 41 28 04 86 97 73 61 ou 73 65 Poste 4508 04 04 04 04 04 04 86 86 91 86 91 91 13 97 22 97 22 82 68 72 34 72 34 88 30 64 41 58 08 29 Unité de Recherche. Centre de Recherche en Cancérologie de Marseille 2/23 Castellano Celis-Gutierrez Cervera Chabannon Chaffanet Chames Charafe-jauffret Charifi Chetaille Chetrit Chevrier Churikov Collette Combes Coppin Corda Cornen Coulier Coulon Daou Daulat David de la Roche Saint André De Sepulveda Dehe Derviaux Devillier Drivet Drogat Dubois Dubreuil Duprez Dusetti Duvivier Fauriat Ferrier Finetti Florentin Fuchs Fujii Gaillard Garcia Garcia Garcia Garcia Garzino Gayet Géli Gelsi-Boyer Geneix Georges Ghossoub Gianardi Gibier Ginestier Gonçalvès Rémy Javier Nathalie Christian Max Patrick Emmanuelle Férose Bruno Bernard Véronique Dmitri Yves Sébastien Émilie Yves Stéphanie François Stéphane Pascale Avais Guido Christophe Paulo Pierre-Marie Carine Raynier Elsa Julie Kenny Patrice Estelle Nelson Laurence Cyril Valérie Pascal Jonathan Robert Shingo Pierre-Henri Julie Maria Noé Maxime Stéphane Patrick Odile Vincent Véronique Jeannine Coralie Rania Fabrice Patrick Christophe Anthony IR IPC thèse Tech IPC PU Cadre IPC CR PUPH postdoc MD PH IE INSERM IR1 INSERM postdoc DR2 MCU thèse CR1 thèse CR1 CR1 thèse postdoc thèse CR1 CR1 postdoc thèse thèse thèse postdoc IE INSERM DR1 DR2 DR2 AI INSERM CR2 Cadre IPC Tech IPC thèse DRCE CR1 CR1 thèse thèse thèse thèse TCE INSERM IE INSERM DR1 MCU Tech IPC AI INSERM Post-Doc TN INSERM AI INSERM CR2 PH 04 86 97 73 04 86 97 72 04 91 22 33 04 91 22 34 04 91 22 34 04 91 82 88 04 91 22 35 04 91 16 43 04 91 22 34 04 86 97 72 04 86 97 72 04 91 16 43 04 86 97 73 04 91 28 82 04 86 97 72 04 91 16 45 Poste 4508 04 86 97 72 04 91 16 45 04 86 97 73 04 86 97 72 32 74 04 41 77 33 09 55 57 07 64 55 31 91 74 80 07 34 21 55 04 91 16 43 66 04 86 97 72 85 04 91 16 42 66 Poste 4508 04 04 04 04 04 04 04 04 04 04 04 04 04 04 04 04 04 04 04 04 04 04 04 04 04 04 04 04 91 91 86 86 91 86 86 91 91 86 91 91 91 91 91 86 91 86 91 91 91 91 86 86 91 86 91 91 16 16 97 97 82 97 97 22 22 97 16 16 16 82 82 97 82 97 82 16 22 22 97 97 26 97 22 22 43 43 72 73 88 72 73 33 33 72 42 43 42 88 88 73 88 73 88 45 41 40 72 73 91 73 35 33 55 21 81 11 28 04 47 52 04 72 71 69 72 15 36 02 22 62 27 32 75 73 83 52 38 62 09 11 Unité de Recherche. Centre de Recherche en Cancérologie de Marseille 3/23 Gondois-Rey Goubard Granjeaud Grasso Guenneau-Puvirajesinghe Guervilly Guillaumond Guille Hamidi Hammam Hamon Hardy Hirsch Imbert Iovanna Isnardon Isogawa Josselin Jourquin Just-Landi Ka Karaki Kashyap Katsogiannou Kerfelec Koubi Laloum Launay Lavaut Le Le Roy Leca Lecocq Lembo Letard Letessier Lhoumeau Lissitzky Liu Livrati Llorente Lombard Loncle Lopez Lopez Luciano Malenfant Mallet Maneville Marchetto Martinez Mezil Mille Modesti Moldawan Monges Françoise Armelle Samuel Daniel Tania Jean-Hugues Fabienne Arnaud Tewfik Kahina Veronique Julien Ivan Anne-Marie Juan Daniel Asako Emmanuelle Frédéric Sylvaine Mignane Sara Rudra Maria Brigitte Myriam Laurence Simon Marie-Noëlle Suong Aude Julie Éric Frédérique Sébastien Anne Anne-Catherine Jean-Claude Xiaoxuan Philippe Bertrand Benjamin Céline Marc Sophie Pierre Carine Françoise Stéphanie Sylvie Sébastien Lynda Delphine Mauro Yvonne Geneviève IR2 INSERM THQ IPC IR1 INSERM thèse Post-Doc postdoc postdoc IE INSERM thèse thèse postdoc thèse DR THQ IPC DR1 IR IPC IR CNRS AI INSERM IE CNRS Tech IPC thèse Thèse thèse postdoc CR thèse TCN INSERM thèse IE AMU thèse thèse thèse TCE INSERM THQ IPC Tech AMU CR2 thèse CR1 postdoc Tech IPC CR1 IE INSERM IE INSERM IR INSERM IR INSERM CR1 Tech INSERM Tech IPC thèse IR2 INSERM thèse thèse TCN INSERM DR2 ATP INSERM PH 04 86 97 72 76 04 86 97 73 32 04 86 97 73 01 04 04 04 04 04 04 04 04 04 04 04 04 04 04 04 04 86 91 91 91 91 86 91 91 86 91 91 86 91 86 91 86 97 16 82 22 82 97 16 16 97 22 82 97 16 97 16 97 72 42 88 33 88 72 41 45 72 34 88 73 43 72 43 73 55 66 06 04 15 84 28 37 71 37 03 64 69 63 55 45 04 04 04 04 04 86 86 91 86 86 97 97 82 97 97 73 72 88 73 72 52 66 33 12 02 04 91 82 88 04 86 97 72 04 86 97 73 04 91 82 88 04 86 97 72 04 86 97 73 04 86 97 72 Poste 4508 04 86 97 72 04 86 97 72 04 86 97 72 04 86 97 73 04 91 16 43 04 91 82 88 04 91 82 88 04 86 97 72 04 86 97 72 04 91 16 45 04 91 22 34 04 86 97 73 04 91 16 41 04 86 97 72 04 86 97 72 04 86 97 72 04 86 97 73 04 91 16 43 04 86 97 73 04 91 22 34 22 76 41 36 84 52 82 54 93 66 45 21 35 15 61 83 80 46 44 28 53 52 63 62 48 61 57 Unité de Recherche. Centre de Recherche en Cancérologie de Marseille 4/23 Morazzani Morelli Morin Mosca Mozziconacci Murati Naiman Négrel Nevoltris Nigri Nunès Olivares Olive Olivares Olivier Orlanducci Orsoni Pages Betty Xavier Stéphanie Cyndie Marie-Joëlle Anne Karel Aurélie Damien Jérémy Jacques Orianne Daniel Orianne Bruno Florence Jean-Christophe Vincent Palud Pasero Pastor Peltier Peuget Philippin Pinet Platet Adeline Christine Sonia Julien Sylvain Gaëlle Isabelle Nadine Poinsignon Pophillat Pouyet Prébet Receveur-Bréchot Restouin Rey Rocchi Rochas Roche Rosnet Roubin Roux Rovere Sabatier Salaun Salvador Santoni Sari Scaglione Sebbagh Secq Seillier Simon Skrobuk Sonongbua Catherine Matthieu Laurent Thomas Véronique Audrey Jérôme Palma Caroline Philippe Olivier Régine Claude Julie Renaud Danièle Marion Marie-Josée Karim Sarah Michaël Véronique Marion Marie-Noëlle Paulina Ying TCE INSERM CR1 thèse IE INSERM PH PH postdoc IE INSERM thèse Tech IPC DR thèse PU PH thèse ATP2 IPC Tech IPC TCE INSERM CR2 Chercheur contractuel CNRS postdoc AI INSERM thèse thèse IE CNRS TCE CNRS IR CNRS Chercheur contractuel CNRS (CEFIC) IE INSERM postdoc PH DR THQ thèse CR1 IE INSERM CR CR1 CR1 IE INSERM Tech IPC med AI INSERM thèse CR1 TN INSERM AI INSERM CR1 med IE INSERM CR1 postdoc thèse 05 86 97 73 33 04 86 97 73 31 04 04 04 04 04 04 04 04 04 04 86 91 91 91 91 91 91 86 91 86 97 22 22 16 16 82 82 97 82 97 72 33 41 43 45 88 88 72 88 72 84 77 75 30 86 34 15 74 36 71 04 04 04 04 91 86 86 91 82 97 97 16 88 73 73 43 29 44 62 30 04 04 04 04 04 04 04 86 86 91 91 91 91 86 97 97 22 82 16 16 97 73 72 33 88 43 41 73 47 76 07 27 94 69 12 04 04 04 04 04 86 86 91 91 86 97 97 22 16 97 72 73 36 45 73 59 32 95 01 32 04 04 04 04 04 04 04 04 04 86 86 91 86 86 86 86 91 86 97 97 16 97 97 97 97 22 97 72 73 45 72 72 72 72 33 73 67 42 06 65 65 05 01 04 21 04 04 04 04 04 04 04 04 86 91 91 86 91 91 91 91 97 82 16 97 82 82 16 82 72 88 42 72 88 88 45 88 56 29 66 57 22 29 37 15 Unité de Recherche. Centre de Recherche en Cancérologie de Marseille 5/23 Soubeyran Soucie Spoto Stahl Stranska Taieb Takedachi Tardivel-Lacombe Termine Tiberi Toiron Tomasini Torres Tournaire Traore Turini Van Hiel Vasseur Verdier-Pinard Verdiglione Vey Viens Vincent-Fabert Vita Wicinski Xerri Yagi Yahiaoui Zhang Zimmermann Philippe Erinn Patricia Olivier Ružena David Arato Joël Elise Guillaume Yves Richard Martine Roselyne Wilfried Marc Boris Sophie Pascal Noémie Norbert Patrice Christelle Marina Julien Luc Yoshihiko Imène Xu Pascale CR1 postdoc TN INSERM THQ IPC postdoc PU PH postdoc IE1D INSERM IE2 INSERM IE INSERM Technicien IPC CR1 AJT CNRS MCU thèse thèse thèse CR1 CR1 IE INSERM PH PUPH postdoc postdoc Tech IPC PU PH IE INSERM thèse thèse DR 04 04 04 04 04 04 04 04 04 04 04 04 04 04 04 04 91 86 91 86 86 86 91 91 91 86 86 91 91 91 86 91 82 97 82 97 97 97 16 82 82 97 97 82 16 82 97 82 88 72 88 73 72 72 42 88 88 73 72 88 41 88 72 88 07 83 29 02 72 67 66 04 33 12 53 15 79 05 52 24 04 04 04 04 04 04 04 04 04 04 04 04 04 91 86 86 91 91 86 86 91 91 91 86 86 86 82 97 97 22 22 97 97 22 22 16 97 97 97 88 73 73 37 37 73 72 34 34 43 73 72 73 06 21 12 54 78 12 85 08 57 94 41 66 51 EQUIPES DE RECHERCHE et THEMATIQUES EQUIPE : E1 - Molecular Oncology RESPONSABLE : BIRBAUM Daniel EQUIPE : E2 - Cell Polarity, Cell Signaling and Cancer RESPONSABLE : BORG Jean-Paul EQUIPE : E3 - Signalling, haematopoiesis and mechanisms of oncogenesis RESPONSABLE : DUBREUIL Patrice EQUIPE : E4 - Tumor Cell Motility RESPONSABLE : BADACHE Ali EQUIPE : E5 - Adhésion Molecules in Tumour/host Interactions RESPONSABLE : AURRAND-LIONS Michel EQUIPE : E6 - Epigenetic control of normal and pathological hematopiesis RESPONSABLE : DUPREZ Estelle EQUIPE : E7 - PDZ scaffold proteins and phosphoinoslitides in cell signalling and oncogenesis RESPONSABLE : ZIMMERMANN Pascale EQUIPE : E8 - Cell stress RESPONSABLE : IOVANNA Juan Unité de Recherche. Centre de Recherche en Cancérologie de Marseille 6/23 EQUIPE : E9 - Tolerance of lesions in DNA RESPONSABLE : FUCHS Robert EQUIPE : E10 - Tolerance, Senescence and DNA damage RESPONSABLE : GELI Vincent EQUIPE : E11 - Mechanisms of DNA double-strand break repair system : homologous recombination and NHEJ RESPONSABLE : MODESTI Mauro EQUIPE : E12 - Control of structure-specific endonucleases and genome stability RESPONSABLE : GAILLARD Pierre-Henri EQUIPE : E13 - Genome dynamics and recombination RESPONSABLE : Llorente Bertrand EQUIPE : E14 - Immunity & Cancer RESPONSABLE : OLIVE Daniel EQUIPE : E15 - Fundamental & Therapeutic Chemical Biology RESPONSABLE : COLLETTE Yves EQUIPE : E16 - Antibody Therapeutics & Immunotargeting RESPONSABLE : BATY Daniel PERSONNELS PAR EQUIPE DE RECHERCHE EQUIPE : E1 - Molecular Oncology RESPONSABLE : BIRBAUM Daniel Acquaviva Acunzo Adélaïde Andrieu Baylot Bertucci Birnbaum Brecqueville Cabaud Carbuccia Cervera Chaffanet Charafe-jauffret Chevrier Cornen Devillier Finetti Gelsi-Boyer Geneix Ginestier Guille Josselin Karaki Katsogiannou Launay Letessier Liu Lopez Claire Julie José Claudia Virginie François Daniel Mandy Olivier Nadine Nathalie Max Emmanuelle Véronique Stéphanie Raynier Pascal Véronique Jeannine Christophe Arnaud Emmanuelle Sara Maria Simon Anne Xiaoxuan Marc Unité de Recherche. Centre de Recherche en Cancérologie de Marseille 7/23 Mezil Monges Mozziconacci Murati Rocchi Rosnet Roubin Sabatier Salvador Taieb Viens Wicinski Lynda Geneviève Marie-Joëlle Anne Palma Olivier Régine Renaud Marion David Patrice Julien EQUIPE : E2 - Cell Polarity, Cell Signaling and Cancer RESPONSABLE : BORG Jean-Paul Bailly Borg Daulat Gonçalvès Guenneau-Puvirajesinghe Lhoumeau Marchetto Martinez Prébet Santoni Sebbagh Toiron Traore Audebert Baudelet Camoin Peltier Pophillat Éric Jean-Paul Avais Anthony Tania Anne-Catherine Sylvie Sébastien Thomas Marie-Josée Michaël Yves Wilfried Stéphane Émilie Luc Julien Matthieu EQUIPE : E3 - Signalling, haematopoiesis and mechanisms of oncogenesis RESPONSABLE : DUBREUIL Patrice De Sepulveda Dubreuil Georges Hammam Lecocq Letard Lopez Mosca Soucie Vita Paulo Patrice Coralie Kahina Éric Sébastien Sophie Cyndie Erinn Marina EQUIPE : E4 - Tumor Cell Motility RESPONSABLE : BADACHE Ali Badache Benseddik Daou Salaun Verdier-Pinard Ali Khedidja Pascale Danièle Pascal Unité de Recherche. Centre de Recherche en Cancérologie de Marseille 8/23 EQUIPE : E5 - Adhésion Molecules in Tumour/host Interactions RESPONSABLE : AURRAND-LIONS Michel Aurrand-Lions Bardin Lissitzky Michel Florence Jean-Claude EQUIPE : E6 - Epigenetic control of normal and pathological hematopiesis RESPONSABLE : DUPREZ Estelle Calmels Chabannon Duprez Imbert Koubi Platet Tiberi Verdiglione Vincent-Fabert Boris Christian Estelle Anne-Marie Myriam Nadine Guillaume Noémie Christelle EQUIPE : E7 - PDZ scaffold proteins and phosphoinoslitides in cell signalling and oncogenesis RESPONSABLE : ZIMMERMANN Pascale Baron-Gaillard David Ghossoub Kashyap Lembo Van Hiel Zimmermann Carole Guido Rania Rudra Frédérique Boris Pascale EQUIPE : E8 - Cell stress RESPONSABLE : IOVANNA Juan Barthet Berthezene Bonacci Borge Brisson Carrier Dusetti Garcia Garcia Garcia Gayet Gianardi Grasso Guillaumond Hamidi Iovanna Lavaut Leca Loncle Nigri Olivares Olivier Marc Patrice Thomas Laurence Lydie Alice Nelson Julie Maria Noé Stéphane Odile Fabrice Daniel Fabienne Tewfik Juan Marie-Noëlle Julie Céline Jérémy Orianne Bruno Unité de Recherche. Centre de Recherche en Cancérologie de Marseille 9/23 Peuget Sari Secq Seillier Skrobuk Soubeyran Spoto Tardivel-Lacombe Tomasini Tournaire Vasseur Sylvain Karim Véronique Marion Paulina Philippe Patricia Joël Richard Roselyne Sophie EQUIPE : E9 - Tolerance of lesions in DNA RESPONSABLE : FUCHS Robert FUCHS Robert FUJII Shingo ISOGAWA Asako PAGES Vincent PALUD Adeline PHILIPPIN Gaëlle POINSIGNON Catherine DR INSERM IR CNRS IR CNRS CR CNRS Chercheur contractuel CNRS IE CNRS Chercheur contractuel CNRS (CEFIC) EQUIPE : E10 - Tolemère, Senescence and DNA damage RESPONSABLE : GELI Vincent Acquaviva Aragnol Audry Charifi Churikov Corda Coulon de la Roche Saint André Drogat Géli Hardy Jourquin Luciano Simon Torres Laurent Denise Julien Férose Dmitri Yves Stéphane Christophe Julie Vincent Julien Frédéric Pierre Marie-Noëlle Martine EQUIPE : E11 - Mechanisms of DNA double-strand break repair system : homologous recombination and NHEJ RESPONSABLE : MODESTI Mauro Bernard Bodin Modesti Négrel Stéphanie Jérome Mauro Aurélie EQUIPE : E12 - Control of structure-specific endonucleases and genome stability RESPONSABLE : GAILLARD Pierre-Henri Dehe Gaillard Guervilly Scaglione Takedachi Pierre-Marie Pierre-Henri Jean-Hugues Sarah Arato Unité de Recherche. Centre de Recherche en Cancérologie de Marseille 10/23 EQUIPE : E13 - Genome dynamics and recombination RESPONSABLE : Llorente Bertrand Arbiol Dubois Llorente Christine Kenny Bertrand EQUIPE : E14 - Immunity & Cancer RESPONSABLE : OLIVE Daniel Afrache Aouar Arnoulet Barbarat Benyamine Blaise Bourdely Celis-Gutierrez Chetaille Coppin Fauriat Florentin Gondois-Rey Hirsch Just-Landi Ka Le Le Roy Livrati Mallet Morin Nunès Olive Orlanducci Pasero Pastor Rey Rochas Sonongbua Stranska Vey Xerri Yahiaoui Hassnae Besma Christine Bernadette Audrey Didier Pierre Javier Bruno Émilie Cyril Jonathan Françoise Ivan Sylvaine Mignane Suong Aude Philippe Françoise Stéphanie Jacques Daniel Florence Christine Sonia Jérôme Caroline Ying Ružena Norbert Luc Imène EQUIPE : E15 - Fundamental & Therapeutic Chemical Biology RESPONSABLE : COLLETTE Yves MORELLI Xavier Basse Betzi Bourgeas Brunel Castellano Chetrit Collette Combes Derviaux Marie jeanne Stéphane Raphaël Jean michel Rémy Bernard Yves Sébastien Carine Unité de Recherche. Centre de Recherche en Cancérologie de Marseille 11/23 Drivet Goubard Hamon Maneville Morazzani Morelli Pouyet Receveur-Bréchot Restouin Roche Zhang Elsa Armelle Veronique Stéphanie Betty Xavier Laurent Véronique Audrey Philippe Xu EQUIPE : E16 - Antibody Therapeutics & Immunotargeting RESPONSABLE : BATY Daniel Agnelli Baty Chames Kerfelec Lombard Nevoltris Rozan Termine Turini Lauren Daniel Patrick Brigitte Benjamin Damien Caroline Elise Marc EQUIPE : E17 - BIOINFORMATIQUE INTEGRATIVE Bidaut Ghislain Garcia Maxime Granjeaud Samuel EQUIPE : E18 - SERVICES COMMUNS Baccini Michel Bapin Luc Birg Françoise Boutchama Henri Coulier François Granjeaud Samuel Garzino Patrick Gibier Patrick Isnardon Daniel Laloum Laurence Mille Delphine Moldawan Yvonne Orsoni Jean-Christophe Pinet Isabelle Roux Claude Rovere Julie Unité de Recherche. Centre de Recherche en Cancérologie de Marseille 12/23 PUBLICATIONS ANNÉES 2010 et 2011 1. Acquaviva,C., Gelsi-Boyer, V., and Birnbaum, D. Myelodysplastic syndromes: lost between two states? Leukemia. 2010;24:1-5. 2. Addou-Klouche,L., Adelaide, J., Finetti, P., Cervera, N., Ferrari, A., Bekhouche, I., Sircoulomb, F., Sotiriou, C., Viens, P., Moulessehoul, S., Bertucci, F., Birnbaum, D., and Chaffanet, M. Loss, mutation and deregulation of L3MBTL4 in breast cancers. Molecular Cancer. 2010;9:2133. Adelaide,J., Gelsi-Boyer, V., Rocquain, J., Carbuccia, N., Birnbaum, D. J., Finetti, P., Bertucci, F., Mozziconacci, M. J., Vey, N., Birnbaum, D., and Chaffanet, M. Gain of CBL-interacting protein, a possible alternative to CBL mutations in myeloid malignancies. Leukemia. 2010;24:1539-1541. 4. Bertucci,F., Finetti, P., Sabatier, R., and Birnbaum, D. The CINSARC signature: prognostic and predictive of response to chemotherapy? Cell Cycle. 2010;9:4025-4027. 5. Bertucci,F., Finetti, P., Birnbaum, D., and Viens, P. Gene expression profiling of inflammatory breast cancer. Cancer. 2010;116:2783-2793. 6. Bidaut, G. Interpreting and Comparing Clustering Experiments Through Graph Visualization and Ontology Statistical Enrichment with the ClutrFree Package. Biomedical Informatics for Cancer Research. [19], 315-333. 2010. Ref Type: Book Chapter 7. Birnbaum,D.J., Sabatier, R., Mamessier, E., Birnbaum, D., and Bertucci, F. Une forme « ariditaire » du cancer de l'ovaire. M/S Medecine Sciences. 2010;26:1040-1042. 8. Carbuccia,N., Trouplin, V., Gelsi-Boyer, V., Murati, A., Rocquain, J., Adelaide, J., Olschwang, S., Xerri, L., Vey, N., Chaffanet, M., Birnbaum, D., and Mozziconacci, M. J. Mutual exclusion of ASXL1 and NPM1 mutations in a series of acute myeloid leukemias. Leukemia. 2010;24:469-473. 9. Chabannon,C., Honstettre, A., Daufresne, L. M., Martin, P. M., Bonnetaud, C., BirtwislePeyrottes, I., Romain, S., Achache, K., Mery, O., Bordonne, O., Ducord, C., Jacotot, L., Vaglio, P., d'Arnoux, C., Figarella-Branger, D., Hofman, P., Borg, J. P., and Atger, V. Publication of biological samples collections catalogues by tumor banks. La publication de catalogues de collections d'échantillons biologiques par les tumorothèques. Bulletin du Cancer. 2010;97:181-189. 10. Chapiro,E., Russell, L., Lainey, E., Kaltenbach, S., Ragu, C., Della-Valle, V., Hanssens, K., Macintyre, E. A., Radford-Weiss, I., Delabesse, E., Cave, H., Mercher, T., Harrison, C. J., NguyenKhac, F., Dubreuil, P., and Bernard, O. A. Activating mutation in the TSLPR gene in B-cell precursor lymphoblastic leukemia. Leukemia. 2010;24:642-645. 11. Charafe-Jauffret,E., Ginestier, C., Iovino, F., Tarpin, C., Diebel, M., Esterni, B., Houvenaeghel, G., Extra, J. M., Bertucci, F., Jacquemier, J., Xerri, L., Dontu, G., Stassi, G., Xiao, Y., Barsky, S. H., Birnbaum, D., Viens, P., and Wicha, M. S. Aldehyde Dehydrogenase 1-Positive Cancer Stem Cells Mediate Metastasis and Poor Clinical Outcome in Inflammatory Breast Cancer. Clinical Cancer Research. 2010;16:45-55. 12. Charafe-Jauffret,E., Ginestier, C., and Birnbaum, D. Cancer stem cells: Just sign here! Cell Cycle. 2010;9:229-230. 13. Coursindel,T., Restouin, A., Dewynter, G., Martinez, J., Collette, Y., and Parrot, I. Stereoselective ring contraction of 2,5-diketopiperazines: an innovative approach to the synthesis of promising bioactive 5-membered scaffolds. Bioorganic Chemistry. 2010;38:210-217. 14. De Lavallade,H., Finetti, P., Carbuccia, N., Khorashad, J. S., Charbonnier, A., Foroni, L., Apperley, J. F., Vey, N., Bertucci, F., Birnbaum, D., and Mozziconacci, M. J. A gene expression signature of primary resistance to imatinib in chronic myeloid leukemia. Leukemia Research. 2010;34:254-257. Unité de Recherche. Centre de Recherche en Cancérologie de Marseille 13/23 15. Derre,L., Rivals, J. P., Jandus, C., Pastor, S., Rimoldi, D., Romero, P., Michielin, O., Olive, D., and Speiser, D. E. BTLA mediates inhibition of human tumor-specific CD8+ T cells that can be partially reversed by vaccination. Journal of Clinical Investigation. 2010;120:157-167. 16. Fei,F., Kweon, S. M., Haataja, L., De Sepulveda, P., Groffen, J., and Heisterkamp, N. The Fer tyrosine kinase regulates interactions of Rho GDP-Dissociation Inhibitor a with the small GTPase Rac. BMC Biochemistry. 2010;11:4817. Fournier,G., Garrido-Urbani, S., Reymond, N., and Lopez, M. Nectin and nectin-like molecules as markers, actors and targets in cancer. M/S Medecine Sciences. 2010;26:273-280. 18. Gelsi-Boyer,V., Trouplin, V., Roquain, J., Adelaide, J., Carbuccia, N., Esterni, B., Finetti, P., Murati, A., Arnoulet, C., Zerazhi, H., Fezoui, H., Tadrist, Z., Nezri, M., Chaffanet, M., Mozziconacci, M. J., Vey, N., and Birnbaum, D. ASXL1 mutation is associated with poor prognosis and acute transformation in chronic myelomonocytic leukaemia. British Journal of Haematology. 2010;151:365-375. 19. Ghiotto,M., Gauthier, L., Serriari, N., Pastor, S., Truneh, A., Nunes, J. A., and Olive, D. PD-L1 and PD-L2 differ in their molecular mechanisms of interaction with PD-1. International Immunology. 2010;22:651-660. 20. Gilabert,M., Audebert, S., Viens, P., Borg, J. P., Bertucci, F., and Goncalves, A. Proteomics and breast cancer: a search for novel diagnostic and theragnostic biomarkers. Bulletin du Cancer. 2010;97:321-339. 21. Ginestier,C., Charafe-Jauffret, E., and Birnbaum, D. Targeting breast cancer stem cells: fishing season open! Breast Cancer Research. 2010;12:31222. Ginestier,C., Liu, S., Diebel, M. E., Korkaya, H., Luo, M., Brown, M., Wicinski, J., Cabaud, O., Charafe-Jauffret, E., Birnbaum, D., Guan, J. L., Dontu, G., and Wicha, M. S. CXCR1 blockade selectively targets human breast cancer stem cells in vitro and in xenografts. Journal of Clinical Investigation. 2010;120:485-497. 23. Giusiano,S., Secq, V., Carcopino, X., Carpentier, S., Andrac, L., Lavaut, M. N., Allasia, C., Bonnier, P., Iovanna, J. L., Garcia, S., Boubli, L., Birnbaum, D., and Charpin, C. 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Centre de Recherche en Cancérologie de Marseille 20/23 CONTRATS ANNÉES 2010 et 2011 Nom projet Pscientifique EQUIPE LABEL LIGUE D BIRNBAUM Date Début Projet 11/03/2010 EQUIPE LABELLISEE LIGUE JP BORG 11/03/2010 31/12/2012 LIGUE S OLSCHWANG 08/04/2010 07/04/2014 EQUIPE LABEL LIGUE P DUBREUIL 01/01/2011 31/12/2013 ARC LIBRE S OLSCHWANG 11/12/2008 30/06/2012 ARC FIXE D BIRNBAUM 23/06/2009 22/06/2011 ARC FIXE Y COLLETTE 10/12/2009 31/12/2011 ARC FIXE M AURRAND-LIONS 10/12/2009 31/12/2010 ARC FIXE D BIRNBAUM 10/12/2009 31/12/2010 ARC FIXE E DUPREZ 10/12/2009 31/12/2011 ARC FIXE A BADACHE 10/08/2010 30/06/2011 ARC S OLSCHWANG 14/10/2010 30/06/2012 ARC FIXE A BADACHE 01/01/2011 30/12/2012 ARC LIBRE D OLIVE 21/09/2011 30/06/2014 FRM JP BORG 28/09/2009 27/09/2010 FRM Installation E DUPREZ 12/05/2010 11/11/2010 FDF E CHARAFFE 15/12/2010 31/12/2013 ASS_L_FUGAIN_DUPREZ E DUPREZ 13/11/2009 30/06/2012 ANRS I HIRSCH 01/06/2009 31/05/2011 ANRS I HIRSCH 01/09/2010 31/08/2012 ANRS D OLIVE 01/03/2011 28/02/2012 CR PACA D BIRNBAUM 28/06/2010 30/06/2014 OSEO P DUBREUIL 12/02/2009 11/02/2013 INCA PL P DUBREUIL 14/12/2007 13/02/2012 INCA PL D OLIVE 14/12/2007 11/02/2011 INCA PL M LOPEZ 14/12/2007 30/11/2010 INCA PL D OLIVE 14/12/2007 30/11/2010 Procan AXE III Y COLLETTE 28/01/2008 31/10/2011 Procan AXE III JP BORG 28/01/2008 31/10/2011 Date Fin Projet 31/12/2012 INCA G BIDAUT 24/01/2008 23/03/2013 Procan AXE II MJ MOZZICONACCI 28/01/2008 31/08/2011 Procan AXE II D BIRNBAUM 28/01/2008 31/08/2011 PROCAN AXE IV D OLIVE 28/01/2008 31/08/2011 INCA PL D BIRNBAUM 17/10/2008 31/08/2012 CANCEROPOLE D BIRNBAUM 16/11/2008 15/11/2011 INCA D BIRNBAUM 29/09/2009 08/04/2013 CANCEROPOLE P DUBREUIL 27/09/2009 26/09/2012 CANCEROPOLE D OLIVE 28/10/2009 13/11/2013 INCA D OLIVE 24/09/2010 23/09/2013 INCA D OLIVE 07/10/2010 30/10/2013 INCA D BIRNBAUM 10/12/2010 09/12/2013 ANR JP BORG 03/02/2009 02/02/2012 ANR L CAMOIN 01/01/2009 30/06/2012 Unité de Recherche. Centre de Recherche en Cancérologie de Marseille 21/23 ANR JP BORG 01/10/2009 30/03/2013 SERVIER D BIRNBAUM 01/01/2010 31/12/2010 THESES de DOCTORAT ANNÉES 2010 et 2011 Nom et Prénom du Doctorant Equipe Titre de la Thèse Date de soutenance GUITTARD Geoffrey OLIVE Signalisation lymphocytaire T : identification d'un nouveau médiateur lipidique, le phosphatidylinositol 5-phosphate (Ptdlns5P) 17/02/2010 STUHL Laetitia DUBREUIL Role de Naca et de ses partenaires moléculaires dans la différenciation erythroide normale et pathologique des syndromes myélodysplasiques 30/03/2010 LENFANT Nicolas REBOUL L'interactome des domaines PDZ de Caenorhabditis elegans 08/06/2010 CHETAILLE Bruno OLIVE Facteurs pronostiques biopathologiques des lymphomes Hodgkiniens: influence du microenvironnement 18/06/2010 BIRNBAUM L’afadine est un marqueur de mauvais pronostic des carcinomes mammaires impliqué dans la croissance tumorale et la migration cellulaire 25/06/2010 CHAIX Amandine DUBREUIL Les spécificités de la signalisation oncogénique par rapport à la signalisation physiologique : le modèle de KIT, un récepteur à activité tyrosine kinase 30/09/2010 ROCQUAIN Julien BIRNBAUM Recherche de nouvelles cibles moléculaires dans les syndromes myélodysplasiques et leucémies aiguës myéloïdes 29/11/2010 BELOTTI Edwige BORG Caractérisation du récepteur de la polarité planaire Vangl2 dans les cancers du sein 21/12/2010 MESSAL Nassima OLIVE Expression, régulation et caractérisation fonctionnelle des molécules de cosignalisation immunitaire, PD-L2 et CD277 dans l’activation lymphocytaire T 20/01/2011 DENTAL Clélia OLIVE Effet du Virus de l'Hépatite C sur les cellules plasmacytoïdes dendritiques 04/03/2011 CHAIB Hassiba OLIVE FOURNIER Gaëlle Unité de Recherche. Centre de Recherche en Cancérologie de Marseille 22/23 Etude d'une nouvelle protéine centrosomale impliquée dans la ciliogenèse, FOR20 13/05/2011 OLIVE PD-1 et BTLA au coeur des lymphocytes B : du physiologique aux lymphomes 05/10/2011 KADRA Gais BORG Prédiction de l'activitè anti-tumoral de Docetaxel, Paclitaxel et Ixabepilone dans le cancer du sein : analyse de profilage d'expression génétique 10/10/2011 FRONTERA Vincent AURRAND-LIONS Caractérisation fonctionnelle des molécules d’adhésion jonctionnelle (JAM) dans l’environnement ganglionnaire et médullaire 06/12/2011 VEUILLEN Caroline OLIVE Caractérisation des mécanismes d'échappement tumoral à la lyse NK dans la LLC-B et le cancer de la prostate 15/11/2011 SEDJAI Fatima BIRNBAUM GHIDOUCHE Abderrezak BIRNBAUM THIBULT Marie-Laure ACCUEIL MASTERS Bioinformatique, Biologie structurale et génomique - Aix-Marseille Développement et Immunologie - Aix-Marseille Pathologie Humaine : Oncologie : pharmacologie et thérapeutique - Aix-Marseille EQUIPEMENTS MAJEURS Trieurs Microscopes Animalerie Unité de Recherche. Centre de Recherche en Cancérologie de Marseille 23/23