education experience research interest

Nicolas GERNIGON
2 rue Molière
35700 RENNES
Date of birth: Dec 29, 1983
Nationality : French
Email : [email protected]
Mobile : +33 (0)6.70.24.15.51
Languages : French, English
EDUCATION
2006-present Ph. D. in Organic Chemistry at the University of Rennes1
Title: Towards new molecules targeting RNA involved in bacterial virulence /
SN2’ Boron Mediated Mitsunobu Reactions
Supervisors: Dr. Fabienne Berrée and Dr. Bertrand Carboni, UMR 6226,
Sciences Chimiques de Rennes,
2005-2006
Master of Molecular Organic Chemistry,
University of Rennes1.
2003-2006
Ecole Nationale Supérieure de Chimie de Rennes (Rennes)
Degree : Chemical Engineer
2001-2003
Preparation for national competitive entrance exams to leading French
"grandes écoles".
2001
Baccalauréat S (equivalent for A level in Science)
EXPERIENCE
02/2006
6 months placement in Dr. Carboni’s group, Department of Chemistry,
University of Rennes1 (France)
Synthesis of Aminoglycosides Derivatives
05/2005
3 months placement in Dr. Britz-McKibbin’s group,
Department of Chemistry, McMaster University (Hamilton, Canada)
Affinity Capillary Electrophoresis using a Water-soluble Recorcin[4]arene as
an Intrinsic Buffer and Electrokinetic Host
06/2004
2 months placement in Prof. Lebreton’s group, Department of Chemistry,
University of Nantes (France)
Synthesis of polyhydroxylated pyrrolidins
RESEARCH INTEREST
•
Synthesis and Studies of Natural Products
•
Carbohydrate Chemistry
•
Synthetic Methodologies
•
Chemical Biology
POSTERS PRESENTATION AND COMMUNICATIONS
2009
“Le groupement boronate: un groupement α-directeur dans la réaction de
Mitsunobu“, Gernigon, N. ; Berrée, F. ; Carboni, B. SECO (Semaine d’Etude
de la Chimie Organique), La Rochelle (France), May 24, 2009
2009
“Antiviral effect of ribonuclease conjugated oligodeoxynucleotides targeting
the IRES RNA of the hepatitis C virus”, Gamble, C.; Trotard, M.; Le Seyec, J.;
Abreu-Guerniou, V.; Gernigon, N.; Berrée, F.; Carboni, B.; Felden, B.; Gillet,
R. Bioorg. Med. Chem. Lett., 2009, 19, 3581-3585
2009
“SN2’ Boron-Mediated Mitsunobu Reactions – A new one-pot Three
Component Synthesis of Substituted Enamides and Enol Benzoates”, Berrée,
F.; Gernigon, N.; Hercouet, A.; Lin, C.H.; Carboni, B. Eur. J. Org. Chem.
2009, 3, 329-333
2008
“Vers de nouvelles molecules ciblant des ARN impliqués dans la virulence
bactérienne”, Gernigon, N.; Berrée, F. ; Gillet, R. ; Felden, B. ; Carboni, B.
Journée Des Doctorants, Rennes (France), December 10, 2008
2007
“Resveratrol Photoisomerization: An Integrative Guided-Inquiry Experiment”,
Bernard, E.; Gernion, N.; Britz-McKibbin, P. J. Chem. Educ. 2007, 84, 11591161
SKILLS
Analytical
NMR, IR, HPLC
Language
French: mother tongue
English: Working knowledge (TOEIC: 805)
Computing
Proficient in the use of Excel, Word, PowerPoint, Chemdraw, ChemSketch,
Scifinder, MestRe-C
Sports
Soccer, triathlon
TEACHING EXPERIENCE
2003-2006
Teacher Assistant at IUT (Institut Universitaire de Technologie) for 1st year
chemists students, 210hours.
REFERENCES
Dr. Bertrand Carboni, Department of Chemistry, University of Rennes1, 263 Avenue du
Général Leclerc, CS 74205 - 35042 Rennes
Phone: +(33) 2 23 23 67 47, [email protected]
Prof. Jacques Lebreton, Department of Chemistry, Faculté des Sciences et des Techniques,
B. P. 92208, 2 rue de la Houssinière, 44322 Nantes cedex 3
Phone: +(33) 2 51 12 54 03, [email protected]
Dr. Caroline Nugier-Chauvin, Ecole Nationale Supérieure de Chimie de Rennes, Avenue du
Général Leclerc, F-35700 Rennes
Phone : +(33) 2 23 23 80 66, [email protected]