recherche et enseignement research and education

Transcription

recherche et enseignement
research and education
2014
sommaire
Préface / Foreword 4
Introduction Research Education 6
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FACE TO FACE Face to face with Mr D, patient at the CHL Face to face with Dr Thérèse Staub Face to face with Dr Jane Thornton
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DEPARTMENTS ›Hemato-Cancerology ›Cardiology › Neuroscience
› Plastic and maxillo facial surgery – Otorhinolaryngology – Ophtalmology – Dermatology
› Pulmonology – Infectious diseases – Immuno-allergology
› Musculoskeletal system › Internal medicine, Adult emergency, Palliative and Geriatric care
› Anesthesiology – Intensive care › Gynecology – Obstetrics › Pediatrics › Gastroenterology, Hepatology, Nephrology and Endocrinology › Surgery (General, Digestive, Vascular, Thoracic, Endocrine, Hepato-Gastroenterologic) – Urology
› Medical Imaging › Healthcare 18
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PUBLICATIONS ACADEMIC TITLES
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32
36
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48
52
CHAPTERS IN BOOKS
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PRESENTATIONS AT CONGRESSES
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90
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préface
foreword
La recherche et l’enseignement dans un hôpital ?
Research and education in a hospital ?
De premier abord, le lien n’est pas évident. L’hôpital est avant tout conçu comme un lieu
où l’on soigne, opère, ou conseille en matière de santé. Pourtant, les patients et les visiteurs
parcourant les couloirs du Centre Hospitalier de Luxembourg croiseront souvent de jeunes
médecins ou étudiants, découvrant ou perfectionnant leur pratique professionnelle. Dans un
service, ils entendront parler de l’une ou l’autre étude clinique, testant des traitements ou
des techniques de soins. Sur une table de salle d’attente, ils trouveront un dépliant, décrivant
les résultats d’un projet de recherche. Au Centre Hospitalier de Luxembourg, recherche et
enseignement font partie du quotidien des médecins et des soignants, et le grand nombre
d’activités décrites dans ce rapport en est le témoin.
The connection is not so straightforward at first glance, as hospitals are mostly seen as
places where we deliver care, perform operations or give health advice. However, visitors
passing through the corridors of the Centre Hospitalier de Luxembourg (CHL) will often
meet junior doctors or medical students who are developing or further advancing their
medical skills. Entering a department, they will hear about this or that clinical study or
tests of treatments or care techniques; on a table in a waiting room, they will find a leaflet
highlighting the results of a research project. At the CHL, research and education are part of
daily life for doctors and carers, as the (we think) impressive number of activities described
in this report bears witness.
En 2014, nos médecins ont contribué à plus d’une centaine de projets de recherche. Ils ont
accueilli une centaine de jeunes médecins, en voie de spécialisation dans l’une ou l’autre
discipline, et ont permis l’organisation de plus de 200 stages dans leurs services pour des
étudiants en médecine. Leurs noms figurent parmi les auteurs de plus de 250 articles de
revues scientifiques internationales ou nationales.
In 2014, our physicians contributed to more than a hundred research projects. They
welcomed around a hundred junior doctors, specialising in one discipline or the other, and
supported the organization of more than 200 internships for medical students in their
departments. Their names are listed as authors or co-authors in more than 250 national and
international journals.
Le Centre Hospitalier de Luxembourg ne peut qu’être fier de ses collaborateurs et de leur
dynamisme. Reconnaissant l’importance de leur travail, il s’est doté, en 2014, de moyens
spécifiques destinés au soutien de l’enseignement et de la recherche, notamment d’une
cellule en charge de leur coordination et de leurs aspects administratifs et techniques. Le
CHL est au cœur d’un réseau de fortes collaborations avec les différentes institutions de
recherche du Grand-Duché, illustrées notamment en 2014 par son implication dans l’arrivée
au Luxembourg du Professeur Rejko Krüger, détenteur de la chaire PEARL 2013 du Fonds
National de la Recherche mais également par les liens avec le Luxembourg Institute of Health
et ses différents départements et laboratoires, avec l’Integrated Biobank Luxembourg et avec
l’Université de Luxembourg. Le CHL cherche aussi à renforcer ses partenariats académiques
en développant et maintenant des contacts avec des universités de médecine belges,
allemandes et françaises. Partenaire de l’Université du Luxembourg pour l’accueil des jeunes
médecins généralistes, il a suivi et continue à suivre avec attention les développements de la
Luxembourg Medical School et leurs implications pour le Luxembourg.
The CHL can only be proud of their dynamism and achievements. In 2014, acknowledging
the importance of this work, the CHL created specific resources to support education
and research, notably a cell in charge of the coordination of these resources and their
administrative and technical aspects. CHL is at the heart of a strong partnership network
with various Luxembourg’s research institutions, as demonstrated not only by its
involvement in welcoming Prof. Rejko Krüger, 2013 PEARL Chair of the Fonds National de
la Recherche but also by the links established with the Luxembourg Institute of Health,
its various departments and laboratories, and with the Integrated BioBank Luxembourg
and the University of Luxembourg. The Centre Hospitalier is also seeking to strengthen
its academic collaboration with Belgian, French and German universities of medicine. As
a partner of the University of Luxembourg, welcoming junior doctors from the University
for general training, the CHL has been closely following developments at the Luxembourg
Medical School and their implications for Luxembourg.
Aucune des activités académiques de recherche ou d’enseignement présentées dans ce
rapport ne serait possible sans l’implication et l’enthousiasme des médecins et la confiance et
le soutien des patients du Centre Hospitalier de Luxembourg.
None of the academic activities described in this report could have been possible without
the involvement and enthusiasm of CHL’s doctors and the trust and support of our patients.
Thank you to everyone !
Merci à tous !
Virginie GIARMANA Dr Guy BERCHEM
Responsable Cellule Enseignement Médical et Recherche Oncologue, Resp. du Comité de Coordination de Recherche
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Dr Marc SCHLESSER
Dr Catherine BOISANTE
Pneumologue, Directeur Médical AdjointAnesthésiste, Directeur Médical
en charge de l’Enseignement et de la Recherche
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RESEARCH
introduction
Research is an integral part of the
mission of the Centre Hospitalier de
Luxembourg. As stated at the time
of its legal foundation in 1975, it is
now one of its distinguishing characteristics in the Luxembourg medical landscape. It also represents
added value for young doctors and
new recruits, who are particularly
interested in the possibility of developing the scientific component of
their work.
Investing in research in a hospital is a guarantee
for all patients that they will be treated with
the best of care available and the latest techniques and treatments. While the majority of
patients receive standard treatment and care,
the fact that their physician is involved in medical research means that they will be aware of
the latest developments in their field, and therefore able to deliver a better diagnostic and
suggest the best treatment options in cases
of rare and complicated disease. At the CHL,
patients who agree to take part in a study can
either contribute to a better understanding of
their pathology, for instance by taking part in
an observational study, (i.e. without a therapeutic intervention) or support the testing of new
drugs and treatment strategies that have not
yet been commercialized but are already in the
latest stages of testing. Involvement of patients
in research programs or studies is voluntary, and
only possible when all of the relevant explanations and detailed information have been provided, with the patient understanding all aspects
of the project and agreeing in writing to take
part. Moreover, physicians at the Centre Hospitalier ensure that all investigations conform to
the Helsinki Declaration1 , which states the international principles and framework regarding all
medical studies and research.
Physicians at the CHL are involved in both fundamental and clinical research. Fundamental research is often managed in cooperation, either
internationally or at the national level, with the
Luxembourg Institute of Health (LIH). Several
laboratories of the LIH are indeed headed or coheaded by physicians from the CHL, namely the
laboratory of cardiovascular research, the laboratory of experimental hemato-oncology, and
the laboratory of sports medicine. Researchers
from the LIH and physicians from the CHL collaborate on numerous fundamental research projects, in cardiology, oncology and sport medicine
most importantly, but also in virology, immunology, allergology and neuroscience. The CHL is
also contributing to several collections led by the
Integrated Bio Bank Luxembourg, one of theLuxembourg Institute of Health bodies.
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RESEARCH
Strong ties have also been formed with the University of Luxembourg, with researchers working on neuroscience, cancer and diabetes. In
2014, the collaboration with the Luxembourg
Center for Systems Biomedicine was strengthened, with the CHL hosting and taking part
in a very important project led by Prof. Rejko
Krüger, FNR (Luxembourg National Research
Fund), the PEARL grantee for 2013 for Parkinson’s disease.
Almost all medical departments of the CHL are
currently involved in clinical studies, as the following pages will demonstrate. Most of these
studies are European and multi-centered, with
the CHL being the main partner in Luxembourg.
For these studies too, a close collaboration exists
with the LIH, particularly with its Clinical and Epidemiological Investigation Center (CIEC), which
is managing the administrative and technical
aspects of several studies, as well as being in
contact with the sponsor (pharmaceutical companies or public/private foundations).
The impressive number of publications with
CHL specialists as authors or co-authors demonstrates the dynamism and the quality of the
medical research led from the Centre Hospitalier de Luxembourg. With more than 250 publications in 2014, most of them in specialized
journals with a registered impact factor2, CHL’s
physicians live up to their hospital’s mission of
research.
2014
saw increasing recognition of the research work done at the Centre Hospitalier
de Luxembourg. For the first time ever, research prizes were awarded to top researchers/physicians from the CHL, during an award ceremony. Three nominees
were selected among the numerous research projects presented :
›Dr Carine de Beaufort, pediatric endocrinologist at the CHL, received the senior prize for translational research, for her work on microbiome and type 1
diabetes
›Dr Pascal Stammet, anesthesiologist at the CHL, received the senior clinical
prize for his work on the importance of body temperature after cardiac arrest
›Dr Julien Wen Hsieh, junior doctor in otorhinolaryngology received the junior
prize for his work on «Smell & Taste Clinic».
Moreover, financial resources have been allocated at the CHL for the recruitment
of a coordinator to take charge of medical education and research with the aim
of facilitating the administrative work surrounding research projects, thereby
supporting physicians in their willingness to get involved in scientific work.
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1http://www.wma.net/en/30publications/ 10policies/
b3/17c.pdf
2 Average impact factor of 4,78
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RESEARCH
Fundamental research
Ongoing Clinical Studies per Year
110
means experimental or theoretical work undertaken primarily to acquire new
knowledge of the underlying foundations of phenomena and observable facts,
without any direct commercial application or use in view.
Ongoing Clinical Studies per Year
108
110
98
83
(ref: Communication from the Commission – “Framework for state aid for
research and development and innovation”, 21/05/2014)
83
73
58
55
Clinical study
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55
means any investigation in relation to humans intended : (a) to discover or verify the clinical, pharmacological or other pharmacodynamic effects of one or
more medicinal products; (b) to identify any adverse reactions to one or more
medicinal products; or (c) to study the absorption, distribution, metabolism and
excretion of one or more medicinal products; with the objective of ascertaining
the safety and/or efficacy of those medicinal products.
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28
0
0
57
50
57
63
82
78
73
98
82
78
108
63
39
40
40
39
40
40
2002
2003
2004
2005
2006
2007
2008
2009
2010
2011
2012
2013
2014
2002
2003
2004
2005
2006
2007
2008
2009
2010
2011
2012
2013
2014
35
35
50
Clinical Studies
(ref: regulation (EU) no 536/2014 of the European Parliament and of
the Council of the European Union, 16/04/2014)
Clinical Studies
108 ongoing studies at
the CHL :
Annual Publications
300
37
14
11
252
10
in hemato-oncology
225
in infectious diseases
150
252
161
in pediatrics
35
Publications (or contribution to publications),
including multiple
references
0
102
87
75
52
19951998 2001-2002
62
41
2004
2005
53
41
2006
Publications
131
125
121
96
171
168
144
147
125
108
131
57
2007
2008
2009
2010
2011
2012
2013
2014
Publications with Impact Factor
11
education
Since its establishment in 1975, the
Centre Hospitalier de Luxembourg
has contributed to the training of
more than 1,500 medical doctors,
either welcoming them during their
student years or their specialization.
Although not officially labeled a university hospital as such, its mission
encompasses the provision of clinical education and training to future
and current physicians, nurses, and
other health professionals, in addition to delivering medical care to
patients. This mission is of utmost
importance for the CHL, as it is the
key to training future generations of
doctors, who might decide to come
and work in the Grand Duchy of
Luxembourg.
Building on its multiculturalism and multilinguism, the CHL has developed collaborations
with Belgian, German and French universities,
welcoming students from these three countries
from their first year of medical studies. For
example, CHL is a recognized teaching hospital
for the University of Saarland (Akademisches
Lehrkrankenhaus). This recognition entitles
German students in their 6th (and last) year of
studies to do their full practical internship year
in Luxembourg. A close cooperation also exists
with the Belgian Catholic University of Louvain,
from which around 50 medical students per
year intern at the CHL.
Medical students come for different lengths of
time, from two weeks to a year, and are expected to take part in the day-to-day running of all
clinical services of the hospital. The fact that
medical students often come back after their
first period of internship to do several others in
different clinical services at the CHL demonstrates the quality of the training provided and
of the tutorship.
Junior doctors stay for longer periods, from 6
months to two years, furthering their specialization in one discipline or the other. Well integrated into the clinical teams, they establish their
own diagnostic and are expected to provide the
right treatment to patients, under the supervision of their tutor. In most of the CHL clinical
services, senior physicians have been recognized by the Belgian Ministry of Health or by
Federal German Chambers of Doctors as official
tutors, and are therefore authorized to assess
and validate the practical training of junior doctors in specialty training. In addition, CHL physicians from most of the hospital departments
and services are also authorized, by the University of Luxembourg, to welcome and train junior
doctors aiming to become general practitioners
in Luxembourg.
To complete the practical training provided
in the different disciplines, physicians also
give theoretical lessons and workshops. These
courses encompass all aspects of medical training, from basic workshops on how to deal with
emergency situations, to highly technical lessons on specific specialties (cardiology, pediatrics, gynecology, endocrinology, etc.).
Junior doctors in specialty training
Junior doctors in general practice training
2014
97
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Internships (medical students, year 1 to 6) 233
›
of which second to sixth year medical students ›
of which medical students from Saarland University in their last year of study ›
of which first year medical students 133
47
53
Recognized trainers for junior doctors 35
›
by German authorities ›
by Belgian authorities ›
by Luxembourg authorities 15
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Last but not least, the CHL welcomes already
specialized physicians who want to further improve their knowledge or learn new techniques
alongside more senior physicians from the CHL
throughout the year.
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13
Face to face with Mr D, patient at the CHL
FACE TO FACE
I am a patient from the Centre Hospitalier de Luxembourg. I have a
very specific lung cancer, diagnosed
three years ago. This type of cancer
is supposedly very rare, affecting
only 2% of people who have lung
cancer. It did take a few months
for a cancerologist to find the right
diagnosis. I first consulted my pulmonologist, who didn’t really know
how to deal with me, so, following
the recommendation of a friend of
mine, I came to the CHL.
We first tried chemotherapy, but the results were
not good. My cancerologist then mentioned a clinical study in which a pharmaceutical company
wanted to test a new treatment, that had not yet
been commercialized. My doctor suggested my inclusion in the protocol, and I accepted. The secondary effects of this treatment were very serious, I
had heavy stomachache, I was exhausted, and the
clinical results were not convincing. After a year, my
cancerologist suggested another treatment, also
in the testing phase and not yet commercialized.
This was one and a half years ago. I am still undergoing the same medical treatment. The secondary effects are a lot less severe, even though
they are still there of course. I live a «normal» life,
I do sports, cycling and running, I am feeling relatively well, and as far as I understand, the cancer
is regressing. Of course, it is quite onerous, I have
to take 8 pills per day, directly provided by the
CHL pharmacy every 4 weeks. Every 6 weeks I
do an IRM and a total body scan, both exams
requested for the protocol and the pharmaceutical company, and my doctor does check very
thoroughly the results and the evolution of the
cancer. He told me recently that he would never
have thought that I could feel so well, and was
not expecting such good results. He added that
if he had seen me 6 years ago, he would never
have been able to help me. I remember indeed,
that he wished me «luck» the first time I met him.
Taking part in a clinical study was a bit like the
last straw. When you are facing a situation such
as mine, when cancer strikes, it takes time to understand, to accept. And then you are ready to
try anything and everything to get better. I even
checked the kind of treatments I could apply for
in other countries, but for the time being, I do not
really see any benefit in trying something else.
My current medical treatment is a lifelong one, at
least as long as it brings results and the pharmaceutical company is providing it.
I am aware that another patient is undergoing
the same medical treatment in Luxembourg, but
I do not know this person.
Today I ran 7 kilometers.
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Face to face with Dr Thérèse Staub
Face to face with Dr Jane Thornton
My name is Thérèse Staub, I am an
infectiologist at the Centre Hospitalier de Luxembourg. I have been
working here for the last 18 years.
In terms of research, we mostly
collaborate with the Laboratory of
Retrovirology from the LIH (Luxembourg Institute of Health) on two
specific issues: HIV (human immuno
deficiency virus, i.e. the AIDS virus)
and hepatitis C.
Visiting report of former rowing
world champion and Olympian,
Dr Jane Thornton from Toronto,
Canada at the Luxembourg Olympic Medical Center, November
2013.
When I first arrived at the CHL, it was the start
of triple drugs therapy for patients infected with
AIDS. We lost patients then that we wouldn’t
lose today. We went from heavy, complicated
treatments which were not working to therapies that allow people to live a normal life. This
is what research means to me - be aware of the
constant evolutions in my medical specialty,
take part in international studies, and find out
things that will improve the lives of patients, and
even sometimes save their life. Today, despite all
the evolutions which have already taken place,
there are still many issues to work on regarding
HIV. Research is focusing either on the best
time to start treatment, or on the possibility of
actually stopping the treatments. Mother/child
transmission of the infection is also a strong
concern.
At the CHL, we have 765 HIV-infected patients. I
would say that there are around 800 HIV-infected people in Luxembourg in total.
Three times more people are infected with hepatitis C in Luxembourg. Official figures indicate
3,000 people, a lot more than in Germany and
slightly more than in Belgium. The virus was
identified 25 years ago. At first, drugs were really strong, even toxic, with heavy secondary side
effects, and we only managed to cure one patient out of two. Hepatitis C is curable today, but
the treatments are very expensive. We mostly
do epidemiologic work, trying to identify all
people infected in Luxembourg and treating the
most seriously affected.
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I remember one of my patients, 10 to 12 years
ago, who took part in a research protocol on
hepatitis C. I contacted him one day, asking
him if he was interested in trying the new early
access medication which we had received. He
was affected by hepatitis C, in a very bad shape,
and had been trying different treatments without success. He started the new experimental
drugs and 6 months later he was feeling great.
Without this new treatment, I am quite sure that
he wouldn’t have made it.
We sometimes see patients who say, from the
very first consultation, that they would be interested in being included in a research project.
To help research or because they are personally
interested. Some others want to get better and
are ready to try anything.
Infectiology is a specialty which has seen unbelievable progress in 25 years. What we thought
of as terminal illnesses when I started working
are today curable, or at least not deadly anymore. A lot still has to be done on HIV and hepatitis C. One major challenge is research on “tropical diseases”, from the southern atmosphere
for which it is very difficult to find funding (malaria, Ebola, other unknown infections that we
have no idea how to deal with, with very few
treatment opportunities). Another quite difficult challenge is discovering new antibiotics. It
has been more than 15 years since we last discovered new antibiotics in infectiology. We are, for
the time being, not able to deal with resistant
bacteria for instance.
Over the span of my decade-long
career with the national rowing team,
I travelled many times ‘across the
pond’ to race in Europe. It was during
this time, in my twenties, when I fell
in love with the number of languages
and cultures just hours away from
each other. After finishing my doctoral studies in sports medicine, I began
medical school with the dream of
doing ‘something international’. My
eyes had been opened and I had a
dream I kept in the back of my mind
to be able to one day practice medicine in Europe, and be a part of an
international community in sports
medicine in particular.
The opportunity arose in my final year of medicine to do a rotation of my choosing. I knew I
wanted to experience more in sports medicine, and I thought an elective in a few different
European countries would satisfy my curiosity.
My goal was to first do an elective in orthopedic surgery in Europe, and I asked a research
colleague, an orthopedic surgeon in Croatia, if
there was a place he would recommend. The
response was immediate - go to Luxembourg
and learn from Prof. Seil and his team. Having
never been to Luxembourg, I didn’t know what
to expect, but set about trying to set up an elective to see what set it apart from the rest.
The answer was obvious right away. I was overwhelmed by the enormous capacity for sports
medicine in a relatively small environment.
The CHL Clinique d’Eich includes the head office of ESSKA, the strong research center of
CRPSante, as well as various medical specialties
including orthopedic surgery, physical medicine
and rehabilitation, general practice, and internal
medicine. Sports medicine here is truly being
approached from every possible angle; and the
result is a magnificent multi-disciplinary team
that is well-positioned to do great things in the
local as well as international community. The
opportunities seem limitless.
Even though I ended up as an elite athlete,
I came from humble beginnings and have always
known that exercise can be beneficial regardless
of the level of physical fitness. Therefore, I also
appreciated the fact that this center is not only
for elite athletes, but also for the recreational
athlete, as well as the patient who wants to
add physical activity to a currently sedentary
lifestyle but might not yet have the tools. It is
encouraging to see a center dedicated to holistic care of the active person, from the novice
to the Olympian. This dedication goes beyond
the walls of the building and out into the community – into the local sports school as well as
large-scale sporting events. Sports medicine
practitioners here have unique expertise to
offer those partaking in physical activity; they
can understand barriers to exercise as well as
suggest very specific training protocols to make
physical activity a sustainable choice in a person’s life. It is inspiring to see the investment in
preventative healthcare that is being made. This
will have a huge payback in the future, as health
care costs increase and the burden of chronic
preventable disease continues to rise across the
globe.
Just as importantly, the welcoming attitude
of the team is not something I’ll soon forget.
I called the orthopedics group I worked with
the “Dream Team” and meant it sincerely. The
enthusiasm of the group is contagious, and the
surgeons and professors are natural teachers.
The time was too short, and it was much harder
to leave than anticipated. I hope to return again
soon, to feel inspired once again!
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HEMATO-CANCEROLOGY
departments
The department of hemato-cancerology provides diagnosis and treatment of blood diseases and solid tumors. The team consists of 5 senior
doctors and 2 junior doctors, led
by Dr Caroline Duhem, head of the
department. In 2014, 8,911 consultations were made for a total of 4,537
patients, and the department accounted for 12,451 days of hospitalization.
Education
Physicians from the department are strongly
committed to sharing their knowledge and expertise with medical students and junior doctors, who are regularly welcome for a few weeks
or months of internships.
Research
In cancerology, fundamental and clinical research focuses on breast and lung cancers and
blood diseases. Clinical research in hematology focuses on myeloma, lymphoma and acute
leukemia, with the involvement of willing patients in studies testing new medical treatments
and drugs.
The two services of the department are currently taking part in around 40 research projects.
Their implementation strongly benefits from the
close collaboration established with research
institutions in Luxembourg : most notably the
Luxembourg Foundation for Research on Cancer and Blood Disorders whose research laboratory is currently headed by Prof Mario Dicato
and several bodies from the Luxembourg Institute of Health, namely, the Integrated BioBank
Luxembourg and the Laboratory of hemato-oncology , led by Dr Guy Berchem.
Moreover, the logistical support of the LIH Clinical and Epidemiological Investigation Center
(CIEC) in managing the administrative aspects
of clinical research projects is fundamental
for CHL clinicians who can then focus on the
science. CHL physicians are regularly involved
in international clinical studies (testing of medicines or of medical preparations), sponsored by
pharmaceutical companies or academic driven
initiatives, alongside other European or international hospitals. The convincing results of some
of these tests might mean finding new cures for
cancer.
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hemato-cancerology
2014 I Research projects I Highlights
The AURORA molecular screening program
for metastatic breast cancer
First-line crizotinib versus chemotherapy in
ALK-positive lung cancer
The Centre Hospitalier de Luxembourg is currently taking part in AURORA, an academia-driven
initiative, aiming to boost genomic and clinical
knowledge generated from metastatic breast
cancer. Detailed molecular profiling of breast
cancer will deepen the current understanding of
the molecular biology underpinning this common
disease, bringing clinicians several steps closer to
the implementation of personalized medicine. To
date, most research efforts have focused on the
molecular analysis of the primary tumor to dissect
the genotypes of the disease. However, accumulating evidence supports a molecular evolution of
breast cancer during its life cycle, with metastatic lesions acquiring new molecular aberrations.
AURORA aims to interrogate the intratumor
heterogeneity of the disease through the coupled genomic analysis of both primary tumor and
metastatic lesions. 1,300 patients are expected to
take part in the study, and they will be followed
for clinical outcomes for 10 years. Depending on
the molecular profiles found, patients could be
directed to innovative clinical trials assessing molecularly targeted agents. So far, 63 samples have
been collected, 8 of which were provided by the
CHL, which was one of the first centers included
in this multinational study.
Berchem G, in Solomon BJ, Mok T, Kim DW, Wu YL,
Nakagawa K, Mekhail T, Felip E, Cappuzzo F, Paolini J,
Usari T, Iyer S, Reisman A, Wilner KD, Tursi J, Blackhall
F and others
Clinical trials in hematology
CHL hematologists are currently involved in
several projects financed and led by the Dutch
foundation HOVON (Hemato-Oncologie voor
Volwassenen Netherlands) on malignant hematological diseases, mostnotably HOVON 95,
which compared different drugs and treatments
in patients with newly diagnosed multiple myeloma, and HOVON 132, which is assessing the
added value of lenalidomide in combination
with standard remission induction chemotherapy in the treatment of young patients. Taking
part in these studies is an opportunity for CHL
physicians to be involved in a broader scientific
network, thereby widening their knowledge of
new treatments and techniques for the ultimate
benefit of their patients.
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2014 I Publications I Highlights
N Engl J Med.2014 Dec 4; 371(23):2167-77.
In December 2014, the New England Journal of
Medicine published the results of an international study on lung cancer in which the CHL and
the LIH took part. The two-year study, under supervision of the European Medical Association,
included 343 participants (male and femaleadults) from around 170 research center all over
the world, one of them the CHL, in collaboration
with the LIH.
The study aimed to evaluate ‘crizotinib’, a new
experimental treatment, and assess whether
its utilization could delay the development of a
certain type of lung cancer, compared to traditional chemotherapy treatment. Selected patients from the CHL could benefit from this new
treatment, with the positive effect of a disappearance of brain metastases and a clear improvement in their quality of life.
Outcome and management of pregnancies in
severe chronic neutropenia patients by the
European Branch of the Severe Chronic Neutropenia International Registry
Zeidler C, Grote UA, Nickel A, Brand B, Carlsson G,
Cortesão E, Dufour C, Duhem C, Notheis G, Papadaki
HA, Tamary H, Tjønnfjord GE, Tucci F, Van Droogenbroeck J, Vermylen C, Voglova J, Xicoy B, Welte K.
Haematologica. 2014 Aug; 99(8):1395-402.
Epub 2014 Jul 4
Long-term granulocyte-colony stimulating factor treatment has been shown to be safe and
effective in severe chronic neutropenia patients.
However, data on its use during pregnancy are
limited. To address this issue, we analyzed all
pregnancies reported to the European branch
of the Severe Chronic Neutropenia International
Registry since 1994. A total of 38 pregnancies
in 21 women with chronic neutropenia (16 pregnancies in 10 women with congenital, 10 in 6
women with cyclic, 12 in 5 women with idiopathic neutropenia) were reported.
Granulocyte-colony stimulating factor was administered throughout pregnancy in 16 women
and for at least one trimester in a further 5 women. No major differences were seen between
treated and untreated women with respect to
pregnancy outcome, newborn complications
and infections. In addition, we evaluated the genetic transmission of known or suspected genetic defects in 16 mothers having 22 newborns
as well as in 8 men fathering 15 children. As a
proof of inheritance, neutropenia was passed
on to the newborn in 58% from female and in
62% from male patients with ELANE mutations,
but also to some newborns from parents with
unknown gene mutation. Based on our results,
granulocyte-colony stimulating factor therapy
has been shown to be safe for mothers throughout pregnancies and for newborns without
any signs of teratogenicity.
2014 I Events and News
Dr Guy Berchem defended his PhD thesis “role
of hypoxic stress in the regulation of the anti-tumor immune response mediated by Natural killerlymphocytes” in December 2014 at Paris Sud
University (Orsay). Dr Berchem was awarded
his PhD with the highest possible marks. He
demonstrated that hypoxic tumor cells, by secreting MVs, can educate NK cells and decrease
their antitumor immune response. This thesis highlights the existence of a novel mechanism of
immune suppression mediated by hypoxic TDMVs and further improves our understanding of
the immunosuppressive mechanisms prevailing
in the hypoxic tumor microenvironment.
Emerging new anticancer biological therapies
in 2013 (hematological malignancies)
Plawny L, Ries F.
Curr Opin Oncol. 2014 May; 26(3):363-70.
Although some hematologic diseases such as
Hodgkin’s lymphoma and aggressive lymphoma yield high response rates and acceptable
overall survival in first-line treatment, relapse is
still a challenge, particularly in those patients
not eligible for transplant. In acute leukemia,
the prognosis remains poor in general with
standard chemotherapy, thus emphasizing the
need for efficient alternate therapies.In recent
years, biological anticancer agents comprising mAbs, small targeted molecules or more
recently bispecific T-cell engaging molecules
or chimeric antigen receptors have been developed in hematologic diseases. This review
examines the recent advances in biotherapies
in the fields of acute leukemia, aggressive lymphoma, Hodgkin’s lymphoma and chronic lymphatic leukemia.
Number of students/
interns and junior
doctors in 2014 :
14
4
Medical
students
Junior
doctors
Number of publications :
28
Articles or
contributions to
articles in national
and international
journals
21
CARDIOLOGY
The department of cardiology deals
with the diagnosis and treatment
of heart and vascular diseases. The
multidisciplinary team provides medical care to patients and devotes
part of its time to support education, prevention and rehabilitation, an essential part of a preventive treatment for further cardiac
incidents. In 2014, 14,950 patients
consulted the team of 10 cardiologists and 5 junior doctors led by Dr
Daniel Wagner, head of the department. The department accounted
for 9,546 days of hospitalization.
Education
Physicians from the department are committed to welcoming medical students and junior
doctors pursuing their specialization. The department also regularly receives high school
students potentially interested in medical studies who are doing short observational internships to have a first exposure to the day to day
life of specialized doctors in a hospital.
Research
Realizing the importance of research to prevent
cardiac diseases and support a quicker and
better rehabilitation of affected patients, the
clinicians of the department consider research
on cardiovascular diseases part of their medical mission. They are currently implementing
several research projects, both in clinical and
fundamental research. Fundamental research
is strongly supported by the involvement of Dr
Daniel Wagner as head of the laboratory of cardiovascular research of the Luxembourg Institute of Health (LIH) and by the close relation
existing with the National Institute of Cardiac
Surgery and Interventional Cardiology (INCCI). Two of the priority areas of fundamental
research are the understanding of the mechanisms responsible for the development of heart
failure following myocardial infarction and the
importance of physical exercise in patients with
heart failure. As for the clinical trials, a few of
them are assessing the pros and cons of technical devices, either aiming at supporting patients
with heart diseases, or at establishing a more
precise diagnosis.
Role of non-coding RNAs in acute myocardial
infarction
Unity is strength – a panel of 4 microRNSs
decreases cardiomyocyte hypertrophy
In a collaborative research project with the Laboratory of Cardiovascular Research from the
Luxembourg Institute of Health, physicians from
the CHL have measured plasma levels of noncoding RNAs (microRNAs and long non-coding
RNAs) in patients with acute myocardial infarction. Based on the data gathered via the enrolment of 414 patients with acute myocardial infarction treated by primary percutaneous coronary
intervention, the team of researchers proved that
certain microRNAs correlate with outcome and
may help to select patients at high risk of complication after myocardial infarction. These promising results motivate further investigation on
the role of long noncoding RNAs after myocardial
infarction.
Goretti E, Zangrando J, Wagner DR, Devaux Y.
Int J Cardiol 2014;24:62-64
Discovered in 1993, microRNAs (miRNAs) are
small (20–23 nucleotides) single stranded noncoding RNAs that modulate gene expression
through target messenger RNA degradation
or translational inhibition. MicroRNAs are participating in multiple biological pathways in the
heart. Circulating miRNAs are stable and have
been proposed as novel biomarkers for personalized health care of patients with cardiovascular disease. Using a system-based approach,
the authors recently identified several miRNAs
with prognostic capacity after myocardial infarction (MI).
Number of students/
interns and junior
doctors in 2014 :
14
8
Medical students
and 4 high school
students
Junior
doctors
14
22
Articles or
contributions to
and international
journals
23
NEUROSCIENCE
REM sleep density in Parkinson’s disease
Diederich NJ, Rufra O, Pieri V, Hipp G, Vaillant M.
The Department of Neuroscience
at the Centre Hospitalier de Luxembourg (CHL) encompasses different
services, all related to disorders of
the central and peripheral nervous
system and disorders of mental
health, i.e. neurology, neurosurgery
and psychiatry. Besides daily clinical
work, each service has developed
several areas of expertise: stroke,
multiple sclerosis, epilepsy, Parkinson’s disease and other movement
disorders for neurology, sexology,
addiction and eating disorders for
psychiatry, and cranial, vascular and
spine surgery as well as neuromodulation for neurosurgery. Neurologists and neurosurgeons also have
a strong technical expertise in different stimulation techniques of the
human brain (e.g. deep brain stimulation, vagal nerve stimulation).
In 2014, 16,641 consultations were
done with 10,826 patients, by the
team of 16 specialized doctors and
5 junior doctors, led by Dr Stefan
Beyenburg, head of the department. The department accounted
24
Education
The department is committed to education and
training, and already has a long tradition of collaboration with different universities, abroad as
well as in Luxembourg. More than 30 medical
students, from their first to their last year of
medical studies, are welcomed per year for an
internship in the three different services. The
service of neurology for instance, welcomes
4 to 6 students from the Medical University
of Cologne twice a year for a week of intense
training. Moreover, several doctors are regularly
involved in academic teaching courses at Universities in Germany (at Bonn, Cologne, Münster, and Homburg).
Research
Several research projects are currently underway, mostly in fundamental research and
mainly on Parkinson’s disease, stroke, epilepsy,
and neurosurgery for brain tumors. The close
collaboration already existing with the Luxembourg
Centre for Systems Biomedicine (LCSB) of the
University of Luxembourg was reinforced in
2014 by the appointment of Prof. Rejko Krüger,
a neurologist specializing in Parkinson’s disease.
Prof. Krüger combines the position of Professor
of Neuroscience at the University of Luxembourg
with that of a physician at the service of neurology
at the CHL, meeting and treating patients, and
leading a very important research project on
Parkinson’s disease. Another privileged partner
is the Laboratory of Neuro-oncology (NORLUX)
from the Luxembourg Institute of Health, with
whom Dr Frank Hertel, neurosurgeon at the
CHL, regularly collaborates. The department
also developed several research collaborations
with German Universities, notably with the
University of Applied Sciences in Trier.
(2013), Lack of polysomnographic Non-REM sleep
changes in early Parkinson’s disease. Mov. Disord., 28:
1443–1446.
In idiopathic Parkinson’s disease (IPD), diseaseinherent degeneration of sleep regulation centers has been postulated, and rapid eye movement (REM) sleep behavior disorder has been
identified as a forerunner syndrome. With longer disease duration, polysomnography (PSG)
evidenced progressive sleep “destructuring.”
At an advanced stage of the disease, patients
with IPD also have lower sleep efficiency and
shorter REM stage than age-matched controls.
However, some of these findings have been collected in cohorts with variable disease duration
and with preferential recruitment of the most
disabled patients. To gather PSG data on sleep
quality and quantity in early motor stages of IPD,
neurologists and researchers decided to use
PSG to search for REM sleep atonia in patients
with early IPD, defined as a disease duration ≤3
years.They also search for other objective sleep
changes, to explore the impact of dopaminergic treatment on sleep quality and quantity, and
finally, to compare subjective sleep complaints
with the PSG data.
Development of automatic planning and evaluation algorithms and analysis of feedback
mechanisms for stereotactic Deep Brain Stimulation procedures and Neuro-navigation
Analysis of tumors and tumor environment interactions in Gliomas
The goal of this cooperative project, implemented
with the Luxembourg Institute of Health (Laboratory of Neuro-Oncology and Clinical and Epidemiological Investigation Center) is to combine basic
with clinical research and develop new innovative
strategies for brain tumor treatments. A number
of experimental models have been established
(e.g. animal models, tumor spheroid models) and
a prospective collection of human brain tumor material has been established since 2008. With this
“tumor bank”, experimental prospective, as well as
retrospective trials could be performed in working
towards personalized brain tumor therapies.
In this translational research project, implemented in cooperation with the Luxembourg
Center for Systems Biomedicine (LCSB) and
the University of Applied Sciences in Trier, engineers, computer scientists, mathematicians and
neurosurgeons work closely together to develop algorithms for planning of stereotactic and
navigated neurosurgical algorithms, as well as
to develop mathematical models for intelligent
stimulators for the future.
The cooperation with the University in Trier has
already existed for 11 years and was enlarged by
the LCSB in 2014. Patents were already developed, and a number of scientific publications
and presentations were written and presented
by members of the group.
25
NEUROSCIENCE
Are patients with Parkinson’s disease blind to
blindsight ?
Diederich NJ, Stebbins G, Schiltz C, Goetz CG.
Brain 2014; 137:1838-1849.
In Parkinson’s disease, visual dysfunction is prominent. Visual hallucinations can be a major hallmark of late stage disease, but numerous visual
deficits also occur in early stage Parkinson’s
disease. Specific retinopathy, deficits in the primary visual pathway and the secondary ventral
and dorsal pathways, as well as dysfunction of
the attention pathways have all been posited as
causes of hallucinations in Parkinson’sdisease.
We present data from patients with Parkinson’sdisease that contrast with a known neuroophthalmological syndrome, termed ‘blindsight’.
Although a large data set on these deficits in
Parkinson’s disease has been accumulated,
consolidation into one specific syndrome has
not been proposed. We propose this synthesis
to prompt refined neuropathological and neuroimaging studies on the pivotal nuclei in these
pathways in order to better understand the
networks underpinning this newly conceptualized syndrome in Parkinson’s disease.
DTI of the visual pathway - white matter tracts
and cerebral lesions
Hana A, Husch A, Gunness VR, Berthold C, Dooms G,
Boecher Schwarz H, Hertel F.
In June 2014, the internationally renowned expert on Parkinson’s disease Prof. Rejko Krüger
started his research in Luxembourg. Backed
by a prestigious grant from the Fonds National de la Recherche Luxembourg, Prof. Krüger
started his work at both the Centre Hospitalier
de Luxembourg (CHL) and at the Luxembourg
Centre for Systems Biomedicine (LCSB) of the
University of Luxembourg.
J Vis Exp. 2014; 26 ;(90). doi: 10.3791/51946.
DTI is a technique that identifies white matter
tracts (WMT) non-invasively in healthy and nonhealthy patients using diffusion measurements.
Similar to visual pathways (VP), WMT are not
visible with classical MRI or intra-operatively
with microscope. DIT will help neurosurgeons to
prevent destruction of the VP while removing
lesions adjacent to this WMT. We have performed DTI on fifty patients before and after surgery between March 2012 and January 2014.
Prof. Krüger has set up a comprehensive clinical
and basic scientific program in which he aims
to involve patients from the CHL. Combining his
medical practice with his research objectives,
he is offering consultations at the CHL for Parkinson’s patients, providing individual advice on
options for treatment and, if these patients are
interested and willing to actively contribute to
the research of their disease, the possibility to
take part in the research project.
Number of students/
interns and MEVS in 2014 :
33
6
Students
Junior
doctors
48
26
Articles or
contributions to
and international
journals
27
PLASTIC AND MAXILLO FACIAL SURGERY – OTORHINOLARYNGOLOGY - OPHTALMOLOGY - DERMATOLOGY
PULMONOLOGY – INFECTIOUS DISEASES –
IMMUNO-ALLERGOLOGY
The department of plastic and maxillo facial surgery, otorhinolaryngology, ophthalmology and dermatology
specializes in the evaluation, diagnosis and treatment of a full spectrum
of ear, nose and throat disorders, as
well as areas within the head and
neck. With a commitment to providing the highest quality care and the
most advanced treatments, the department has strongly developed its
medico-technical infrastructures to
treat pathologies related to the loss
of senses and communication: hearing, taste, smell, voice and balance
(equilibrium). More than 20,000 patients per year consult the team of
6 medical doctors and 5 junior doctors led by Dr Jérôme Keghian, head
of the department. In 2014, the department accounted for 5,440 days
of hospitalization.
The department combines three
complementary services, two of
which, “infectious diseases” and “immuno-allergology”, are recognized as
national services1. In pulmonology,
the team provides comprehensive
care for the full range of respiratory
conditions and diseases, from asthma to COPD (chronic obstructive
pulmonary disease), lung cancer,
cystic fibrosis and HTAP (hypertension pulmonary artery). In infectiology, the team is specialized in the
prevention, diagnosis and therapy
of all infectious diseases, from pneumonia to HIV. The immuno-allergology service deals with common and
rare allergies (to pneumallergen,
trophallergen and drugs), as well as
more complex and rare immunodeficiencies in adults and children.
In 2014, the specialized team of 11
senior doctors and 3 junior doctors,
led by Dr Catherine Charpentier,
head of the department, performed
24,794 consultations for 16,391 patients. The department accounted
Dr Julien Hsieh from the otorhinolaryngology
department was awarded the 2014 CHL junior prize for his research on smell and taste.
Dr Hsieh, who spent a year at the CHL to complete his training as an ORL specialist, focused
his research on the olfactory function and most
particularly on smell disorders, seeking ways
to identify these disorders and treat them. His
research gave rise to a manuscript which could
be used as a guideline book for junior and specialized doctors. He also contributed to the development of a new olfactory test which would
allow an olfactory assessment for patients.
Education
The department is committed to welcoming and
training junior doctors and medical students
who can benefit from the extensive expertise of
senior specialists in otolaryngology.
Number of students/
interns and junior
doctors in 2014 :
Research
Research in the department focuses on the
olfactory function with preliminary works on
the development of a “smell and taste clinic” in
Luxembourg. This work is led in collaboration
with Geneva University Hospital, and particularly its rhinology and olfactory department.
28
4
students, from which 2 high
school students who spent a
week at the CHL to discover
the work of a medical doctor
9
Junior
doctors
Education
Physicians from the department welcome and
train medical students and junior doctors pursuing their specialization every year. Future
family doctors completing their training at the
University of Luxembourg regularly gain practical experience in the different services of the
department.
Research
The department has strong ties to the Luxembourg Institute of Health, with several fruitful
collaborations in fundamental research, mostly
on immunology and infectiology, as well as clinical research, with an ongoing involvement of
the Clinical and Epidemiological Investigation
Center (CIEC) in several studies currently implemented at the CHL. The current director of the
Luxembourg Institute of Health, Dr Jean-Claude
Schmit, is also an infectiologist at the CHL.
Due to its strong involvement in prevention
by avoiding tobacco and the consequences of
smoking, research in pulmonology mostly focus
on chronic obstructive pulmonary disease and
lung cancer and its treatment. Pulmonologists
also work on cystic fibrosis and contribute to
several European wide studies and registers.
Fundamental research in allergology focuses
on food anaphylaxis, with several studies dealing with diagnostic and potential therapies for
food allergies. Research on respiratory allergies
is a second axis of work for CHL allergologists,
with a strong focus on allergies to rodents. As
for infectiology, the strong collaboration with
the LIH Laboratory of Retrovirology is leading
several projects on HIV and Hepatitis C.
1 National services in Luxembourg are responsible, by acknowledgment of the Luxembourg Ministry of Health, for
providing care to all patients living in the country and affected by a disease related to the expertise and skills of the
specialized physicians of its service.
29
PULMONOLOGY – INFECTIOUS DISEASES – IMMUNO-ALLERGOLOGY
Bronchial airway gene expression in smokers
with lung or head and neck cancer
Asthma and smoking : a dangerous mix
Charpentier-Chaix C, Abou Hamdan K, Wirtz G, Morisset M, Schlesser M.
Van Dyck E, Nazarov PV, Muller A, Nicot N, Bosseler M, Pierson S, Van Moer K, Palissot V, Mascaux C,
Knolle U, Ninane V, Nati R, Bremnes RM, Vallar L, Berchem G, Schlesser M.
Reference: Le courrier des addictions, vol.16 : n1
(2014/01/02/03) – p 16-19
Smoking is as common in those suffering from
asthma as it is in the general population. Active
and passive smoking increase the risks of asthma and severe asthma, of the persistence of
asthma in children, of resistance in inhaled corticosteroid treatment and of a greater decline of
the respiratory function. Prevention of smoking
in asthmatic adolescents as well as smoking
cessation for adults affected with asthma are a
strong necessity.
Référence: Cancer Med, 2014 Apr;3(2):322-36.
Epub 2014 Feb 4.
Cigarette smoking is the major cause of cancers
of the respiratory tract, including non-small cell
lung cancer and head and neck cancer. In order
to better understand carcinogenesis of the lung
and upper airways, researchers compared the
gene expression profiles of tumor-distant, histologically normal bronchial biopsy specimens
obtained from current smokers with non-small
cell lung cancer or head and neck cancer, as
well as nonsmokers and smokers without cancer. A total of 97 biopsies were used for gene
expression profiling. Smoking-related cancer
of the respiratory tract was found to affect
the expression of genes encoding xenobiotic
biotransformation proteins, as well as proteins
associated with crucial inflammation/immunity
pathways and other processes that protect the
airways from the chemicals in cigarette smoke
or contribute to carcinogenesis.
Strategic timing of antiretroviral treatment
(START)
Primarily financed by the National Institute
of Allergy and Infectious Diseases, one of the
American National Institutes of Health, this multicenter study led by the University of Minnesota aims to find out the best time to start taking
HIV medicines for people infected with HIV. Researchers are trying to find out if the chances of
getting one serious illnesses (heart attacks, liver
disease, or kidney failure) or of getting AIDS are
less if patients start taking HIV medicines at a
time when the CD4 count is still high instead of
at a later stage. The CHL is one of the several
centers taking part in the study, and has been
enrolling patients since 2011.
Results of the study should be published in 2015,
answering for the first time the most important
question “when is it better to start treatment?”.
30
Virological and immunological outcomes of
elvitegravir-based regimen in a treatmentnaïve HIV-2-infected patient
Zheng Y, Lambert C, Arendt V, Seguin-Devaux C.
Allergies to rodents
Reference: AIDS, 2014 Sep24; 28(15):2329-31
Identification and isolation of a FEL d 1-like molecule as a major rabbit allergen
Treatment options are limited in HIV2 patients.
This article describes the first case of elvitegravir
use in a treatment-naïve HIV-2 patient. This treatment was successful, showing that FTC/TDF/EVG
could be a drug of choice for HIV-2 patients.
Hilger C, Kler S, Arumugam K, Revets D, Muller CP,
Charpentier C, Lehners C, Morisset M, Hentges F.
Reference: Journal of Allergy and Clinical Immunology, vol 133, number 3, 753-766, march 2014
After working for several years on rodent allergies, the service of immune allergology reached
a milestone in this project in 2014, by identifying
and isolating a FEL d 1-like molecule as a major
rabbit allergen. Rabbits are increasingly kept
as domestic pets. Several rabbit allergens have
been characterized. However, their sequences
are still elusive and none of these molecules are
available for diagnosis. Researchers sought to
isolate major allergens from the rabbit oryctolagus cuniculus and to investigate their importance in sensitized patients.
Number of students/
interns and junior
doctors in 2014 :
25
6
students, from
which 2 high school
students who spent
a week at the CHL to
discover the work of
a medical doctor
Junior
doctors
60
Articles or
contributions to
and international
journals
Chapter “food anaphylaxis prevention” in “Advances in anaphylaxis management”
Future Medicine Ltd, April 2014, 143 pages, pages
108-123
In this chapter, Dr Morisset acknowledges that
under pressure from patient groups and professional networks, significant progress has beenmade by health authorities over the last 20 years
in North America, Australia and Europe toimprove the prevention of life-threatening anaphylaxis. She adds that prevention also requires
a clear identification of factors that contribute
to the aggravation ofthe clinical expression of
allergy. The rise of biotechnology may lead to
a better detection of high-risk allergens.Secondary prevention is also based on a training of
patients and their entourage to avoid riskfoods
and to recognize the symptoms of anaphylaxis
and how to use of the emergency kit.
The therapeutic controls of the underlying chronic allergic disease, and especially the development of specific immunotherapy in recent
years, have become essential items of themanagement of food anaphylaxis.
31
MUSCULOSKELETAL SYSTEM
The department of the musculoskeletal system deals withboth pathologies like congenital, degenerative,
traumatic and inflammatory bone
and joint diseases, physical handicap and the benefits and downsides of physical exercise. It hosts
the services of orthopedic surgery,
trauma surgery, sports medicine, rehabilitation medicine and rheumatology. The medical team consists
of 20 senior specialized physicians
and 8 junior doctors. In 2014, the
surgeons of the department performed around 2,700 surgical procedures. 43,714 consultations were
done with 16,953 patients. The department accounted for 15,551 days
of hospitalization.
32
Besides this clinical expertise, many members
of the department have a strong academic
orientation. Four of its physicians have an appointment as extraordinary professors in German universities with whom they collaborate
through either education or research activities.
Other doctors are involved in the teaching programs of national or foreign schools of higher
education. Through these teaching and scientific activities, the members of the Department
are credited with a high international recognition and credibility among their peers in their
respective fields of medical specialization. Their
scientific work contributes to the development
of medicine for the benefit of all patients.
Education
From an educational perspective, physicians are
active at various levels. They welcome doctors
and medical students at different time points
of their educational curriculum: from pre-clinical internships to postgraduate subspecialty
medical education. In 2014, seven young MDs
performed their specialized medical education
in orthopedics and traumatology in the department. The sports medicine service welcomed
its first resident educated according to a unique
training curriculum, specifically adapted to the
needs of the Luxembourg sports medicine environment. Furthermore, future family doctors
from the University of Luxembourg are regularly hosted in the department. Physicians are
supervising candidates for masters and PhD
theses for students in medicine, engineering,
physiotherapy etc. in collaboration with Universities and Schools of Higher Education in
Luxembourg, the Greater Region Saarlorlux and
beyond.
Research
Research in the Department focuses around
the development of new surgical techniques in
orthopedic and trauma surgery, the improvement of diagnostic procedures of pathologies of
the musculoskeletal system following an injury
or surgery, the optimization of the rehabilitation
process, as well as the maximization of the clinical outcome of patients. The Department has two
privileged research partners: the Sports Medicine
Research Laboratory of the Luxembourg Institute
of Health, directed by Prof. Daniel Theisen, PTPhD and co-directed by Profs. Romain Seil, Axel
Urhausen and Dietrich Pape, and the Department
of Experimental Orthopedics of the University of
Saarland, Homburg-Saar, Germany, directed by
Prof. Henning Madry. The clinician-researchers
of the Department are organized in the Cartilage
Net of the Greater Region Saarlorlux.
The department is currently implementing the
following five research programs, both in clinical and fundamental research (principal investigators in brackets) :
•
•
•
•
•
Geriatric fracture (Prof. TorstenGerich)
Knee osteotomy (Prof. Dietrich Pape)
Knee soft tissue (Prof. Romain Seil)
Knee replacement (Prof. Romain Seil)
Physical exercise (Prof. Axel Urhausen)
Research project on ruptures of the anterior
cruciate ligament (ACL)
Combined anterior and rotational laxity measurements allow characterizing personal knee laxity profiles in healthy individuals
Mouton C, Seil R, Meyer T, Agostinis H, Theisen D.
Knee Surg Sports Traumatol Arthrosc. 2014, Aug 26
The project is part of the CHL knee soft tissue
research program and more specifically of the
ACL clinical pathway. This is an interdisciplinary
initiative by the CHL and the sports medicine
research laboratory of the Luxembourg Institute
of Health. It is co-funded by public bodies like
the Fonds National de la Recherche (FNR) as
well as the “Oeuvre Grande Duchesse Charlotte”. Its goal is to gain knowledge in the treatment of ACL injured patients. In the framework
of this project, our researchers managed to
quantify physiological knee laxity, i.e. the natural
knee laxity of non-symptomatic and non-traumatic individuals. Based on physical and technical tests made on 104 healthy participants, the
investigators confirmed the diversity of laxity
profiles and highlighted the complexity of the
interpretation of multidirectional knee laxity,
suggesting the necessity for individualized care
of knee diseases and injuries. Their conclusions
contributed to the understanding of knee laxity
and drew the basis for prevention strategies
and improvement of treatment outcomes in
injuries and diseases.
33
musculoskeletal system
Hidden Lesions of the Posterior Horn of the
Medial Meniscus - a Systematic Arthroscopic
Exploration of the Concealed Portion of the
Knee
Sonnery-Cottet B, Conteduca J, Thaunat M, Gunepin
FX, Seil R.
American Journal of Sports Med., 2014 Apr;42(4):921-6
Anterior cruciate ligament (ACL) tears are
frequently associated with meniscal lesions.
Despite improvements in meniscal repair techniques, failure rates remain significant, especially for the posterior horn of the medial meniscus.
A collaborative work between researchers from
the Centre Hospitalier de Luxembourg and the
Clinique Santy from Lyon aimed at determining
whether a systematic arthroscopic exploration
of the posterior horn of the medial meniscus
with an additional posteromedial portal is useful to identify otherwise unrecognized lesions.
The article describes the methods used and the
analysis of the results and concludes that posterior visualization and posteromedial probing of
the posterior horn of the medial meniscus can
help in discovering a higher rate of lesions that
could be easily missed through a standard anterior exploration.
Iliopubicsubcutaneous plate osteosynthesis
for osteoporotic fractures of the anteriorpelvic
ring. An alternative to the supra-acetabularexternalfixator.
Gerich T, Bogdan A, Backes F, Gillman T, Seil R, Pape D.
Bull Soc Sci Med Grand DucheLuxemb.2014 ;(1):7-14.
The majority of fractures of the anteriorpelvic ring aretreated non-operatively. However,
a number of patients do not become pain free
and can not bemobilized. So far, the first choice
of treatment has been a fracture immobilization
with a supra-acetabularexternalfixator. However, this procedure is associated with significant complications. Therefore, an alternative
technique based on recent anatomical studies
was developed by the trauma team of the Department. The article reflects a clinical feasibility study to evaluate a novel stabilization technique for fractures of the anteriorpelvic ring in
the elderly patient. This technique obtains rapid
pain reduction, early ambulation and functional
recovery in this group of patients which are at
high risk for comorbidities.
Congress of the French Arthroscopic society
in Luxembourg
For the first time ever, Luxembourg hosted the
annual congress of the French Arthroscopic society from the 4th to the 6th of December. Presided by Prof. Romain Seil, head of the department, the congress welcomed more than 1600
participants from allover Europe who gathered
in Luxembourg, to discuss recent developments
in arthroscopy and exchange views and expertise. Two symposia, 3 guest lectures, several instructional course lectures, debates and discussion took place over the course of these three
eventful days. A specific research day was organized by the department in collaboration with
Prof. Madry’s team from the University of Saarland. The congress benefited from the financial
support of several sponsors, among them the
National Research Fund Luxembourg
(see: http://www.fnr.lu/fnr-publications/annual-reports annual report 2014, pp 20-21)
Promotion of physicalactivity for secondary
prevention in patients with chronic diseases:
the situation in the Grand-Duchy of Luxembourg
Lion A, Urhausen A, Delagardelle C, Seil R, Theisen D.
Osteotomy techniques close to the knee. Effect on wedge volume and bony contact surface
Pape D, van Heerwaarden R, Haag M, Seil R, Madry H.
Der Orthopade 2014 Nov;43 (11): 966-75
Bone geometry following osteotomy around
the knee suggests that biplanar rather than uniplanar open wedge techniques simultaneously
create smaller wedge volumes and larger bone
surface areas. However, precise data on the
bone surface area and wedge volume resulting
from both open and closed wedge high tibial
osteotomy (HTO) and distal femoral osteotomy
(DFO) techniques remain unknown. Collaboration between physicians from the CHL and from
the MaartenskliniekWoerden, as well as researchers from the University of Luxembourg, hypothesized that biplanar rather than uniplanar
osteotomy techniques better reflect the ideal
geometrical requirements for bone healing,
representing a large cancellous bone surface
combined with a small wedge volume.
34
Bull Soc Sci Med Grand Duche Luxemb. 2014 ;(3):57-72.
The regular practice of physical activity has
health benefits in healthy subjects (primary prevention) and in patients with non-communicable
diseases (secondary prevention). This study aimed to perform a stocktaking of the physical
activities programs for patients or individuals
at risk in the Grand-Duchy of Luxembourg. Eleven organizations offering therapeutic physical
activities (TPA) have been identified. The national coverage is quite low, especially for obesity,
neurology and orthopedics. This low rate is related to a lack of information and to organizational constraints. These private initiatives compensate for the current lack of concrete action
of the public and private authorities. The public
health action initiated by these groups should
be perpetuated and strengthened with a better
structuration and professionalization. The studyis part of a program funded by the «Œuvre
Grande-Duchesse Charlotte» to develop physica activity as a tool for secondary prevention
in various diseases in Luxembourg.
Number of students/
interns and junior
doctors in 2014 :
11
4
Students
Junior
doctors
53
Articles or
contributions to
and international
journals
35
INTERNAL MEDICINE, ADULT EMERGENCY,
PALLIATIVE AND GERIATRIC CARE
The department was recently reorganized and now encompasses several different services. Emergency
care is the first point of contact for
adult with acute health issues. It
provides diagnosis and treatment,
while dispatching patients to the
more specialized departments and
services. Geriatric care works closely with the emergency unit by taking care of aging patients in need
of hospitalization and special treatments. Medical doctors and nurses
from the team also intervene in all
departments and services of the
CHL when needed. This is also the
case for the professionals from the
palliative care service, which is also
managing a 10-bed unit.
In 2014, 36,251 patients consulted
the team of 16 medical doctors
led by Dr Michel Petit, head of the
department. The department accounted for 19,687 days of hospitalization.
Physicians from the palliative care service took
part in a study led by the multidisciplinary
European Association of Palliative Care which
aim was to learn what facilitates and hinders
the development of palliative care in the community across Europe. Acknowledging that
most people who are dying, unless they have
cancer, still fail to access generalist or specific
palliative care, researchers sought to identify
barriers and opportunities for palliative care in
the community. A toolkit was then constructed, suggesting various innovations and approaches and highlighting examples of innovations and best practice in various European
countries.
Promoting palliative care in the community:
production of the primary palliative care toolkit by the European Association of Palliative
Care Taskforce in primary palliative care
Murray SA, Firth A, Schneider N, Van den Eynden B,
Gomez-Batiste X, Brogaard T, Villanueva T, Abela J,
Eychmuller S, Mitchell G, Downing J, Sallnow L, van
Rijswijk E, Barnard A, Lynch M, Fogen F, Moine S.
Palliat Med. Epub 2014 Nov 13.vhttp://www.eapcnet.
eu/Portals/0/Clinical/Publications/PM201529(2)Murray.pdf
ANESTHESIOLOGY – INTENSIVE CARE
The department combines two
complementary medical services.
In anesthesiology, the team has a
strong expertise in anesthesia and
post-operative supervision of patients dealing with complex pathologies such as morbid obesity,
neurosurgery, pediatric and neonatology. Intensive care medicine
takes care of patients whose vital
functions are failing and ensures
post-operative follow-up of heavy
surgery. In 2014, 16,518 patients
consulted the team of 22 specialized doctors and 3 junior doctors,
led by Dr Philippe Robert. The department accounted for 7,045 days
of hospitalization.
Education
train medical students and junior doctors pursuing their specialization each year.
Research
Physicians from the intensive care unit work in
close collaboration with CHL cardiologists, with
a strong focus on cardiac arrest. Current research focuses on the outcome after resuscitation from cardiac arrest, and particularly on the
exploration of new and known biomarkers. This
research aims at contributing to a better evaluation of the neurological impact after a cardiac
arrest and better care for those patients.
Although the team’s involvement in research is
fairly recent, it has already contributed to several international research projects, one of which
achieved great recognition in 2013 with a publication in the New England Journal of Medicine,
one of the most prestigious medical journals in
the world.
Education and research
Physicians from the department are seldom involved in medical research. Moreover, the complex and emotional nature of the work in these
specific services has an impact on the number
and level of competences of medical students
accepted in the department. Only the most advanced students from their 3rd to their last year
of medical studies can do an internship in the
different services of the department.
36
Number of students/
interns and junior
doctors in 2014 :
11
medical
students
37
ANESTHESIOLOGY – INTENSIVE CARE
NorthPole study (Biosignature to Predict Outcome after Hypothermia for Patients Surviving
Cardiac Arrest)
As the first researchers to describe micro-RNAs
as biosignatures after cardiac arrest in 2012, CHL
physicians are currently involved in a follow up
project, aiming to discover new and not yet described biomarkers and biosignatures (expression
and levels of different markers in the blood) in
patients initially successfully resuscitated from
cardiac arrest.Patient data are collected, as well
as blood samples drawn 48 hours after cardiac
arrest for analysis, with the goal of identifying
markers for outcome prediction after cardiac
arrest. This project developed thanks to collaboration between the departments of anesthesiology and cardiology at the CHL, with the national
institute for cardiac surgery and interventional
surgery (INCCI) and with the laboratory of cardiovascular research of the Luxembourg Institute of Health. Bringing together all the relevant
partners in cardiac and intensive care research
from Luxembourg, this project is an illustration
of the importance of the CHL as a clinical partner
within the research landscape of the country.
Bispectral index to predict neurological outcome early after cardiac arrest
0.89, a specificity of 89% and a sensitivity of 86%
using a cut-off value of 23. With specificity fixed
at 100% (sensitivity 26%) the cut-off BIS value
was 2.4 over the first 271 minutes. In multivariable
analyses including clinical characteristics, mean
BIS value over the first 12.5 hours was a predictor
of neurological outcome (p = 6E-6) and provided
a continuous net reclassification index of 1.28% (p
= 4E-10) and an integrated discrimination improvement of 0.31 (p = 1E-10).
Mean BIS value calculated over the first 12.5 hours
after ICU admission potentially predicts 6-month
neurological outcome after cardiac arrest.
Dr Pascal Stammet, anesthesiologist, was
awarded the CHL Senior Science Award for
Clinical Research in May 2014 for his work on
the Targeted Temperature Management (TTM)
trial, an international, multi-center, randomized
clinical trial. The first results from the study, published in the prestigious New England Journal
of Medicine (2013), suggested that therapeutic
hypothermia, as recommended by international
guidelines for the treatment of cardiac arrests,
may not actually be beneficial for survival. The
investigators found that hypothermia at a targeted temperature of 33°C did not confer a
benefit as compared with a targeted temperature of 36°C.
In this prospective observational study in adult
comatose patients treated by therapeutic hypothermia after cardiac arrest we measured bispectral index (BIS) during the first 24 hours of
intensive care unit stay. A blinded neurological
outcome assessment by cerebral performance
category (CPC) was done 6 months after cardiac
arrest. Forty-six patients (48%) had a good neurological outcome at 6months, as defined by a
cerebral performance category (CPC) 1-2, and 50
patients (52%) had a poor neurological outcome
(CPC 3-5). Over the 24 hours of monitoring, mean
BIS values over time were higher in the good outcome group (38 ± 9) compared to the poor outcome group (17 ± 12) (p < 0.001). Analysis of BIS
recorded every 30 minutes provided an optimal
prediction after 12.5 hours, with an area under the
receiver operating characteristic curve (AUC) of
38
The department of gynecology offers a full spectrum of care regarding
women’s health, from gynecological
and surgical consultations, to pregnancies and emergency obstetrical
and gynecological care. The department also encompasses a fertility
service, dealing with in-vitro fecundation and all questions related to
sterility. The team of highly skilled
physicians has also built up expertise
in gynecological surgery. More than
17,000 patients per year consult the
team of 9 senior gynecologists (8
gynecologists and 1 physician specializing in assisted reproduction)
and 5 junior doctors and the department welcomes around 2,200 newborns per year. In 2014, it accounted
Gynecologists from the CHL took part in an
exceptional surgery performed on a young
woman in her 19th week of pregnancy, for a
unilateral gigantomastia, secondary to a rapidgrowth giant hamartoma during her second
pregnancy. Breast hamartoma is a benign
tumor consisting of fat, fibrous and glandular
tissue. Rigorous clinical and ultrasonographic
examinations were performed followed by
multiple biopsies. The decision to perform surgery was guided by the risk to skin integrity
and of tumor infarct. Our report provides detailed information on gestational benign breast
tumors, on the specificities of medical imaging
and breast surgery in pregnant patients.
Gigantomastie unilatérale gravidique : à propos
d’un cas d’hamartome géant
Kuhn-Beck F, Foessel L, Bretz-Grenier M.-F, Youssef
Akladios C, Mathelin C
Gynécologie Obstétrique & Fertilité, Volume 42, Issue
6, Pages 444-447
Education and research
Stammet P, Collignon O, Werer C, Sertznig C, Devaux Y.
Resuscitation. 2014 Dec;85(12):1674-80.
Epub 2014 Sep 23.
GYNECOLOGY – OBSTETRICS
Number of students/
interns and junior
doctors in 2014 :
7
Junior
doctors
4
Articles or
contributions to
articles in national and
international journals
Due to time constraints, gynecologists and
obstetricians are seldom involved in research
projects. The department is, however, a well-recognized training center for junior doctors and
medical students. Five junior doctors, completing their specialization in gynecology-obstetrics
are part of the team at all times and contribute to
all aspects of the medical care offered. Moreover,
thanks to the strong ties built up over the years
with several Belgian faculties of medicine, as well
as with the German university of Saarland, 3 to
4 medical students are present all year round,
spending 8 to 16 weeks interning in the different
services of the department in rotation.
Number of students/
interns and MEVS in 2014 :
14
9
Students
Junior doctors
39
PEDIATRICS
The department of pediatrics provides care for children and their families from birth until adolescence.
The department encompasses the
complete range of pediatric specialties (from neonatology to pedopsychiatry) and therefore plays
the role at the national level of a
center of reference for pediatrics
diseases and disorders. In 2012, the
service of pediatric endocrinology
was recognized as European center of reference for pediatric diabetes by the international society
for pediatric and adolescent diabetes, based on their evaluation of
the quality of care provided at the
Centre Hospitalier de Luxembourg.
In 2014, the specialized team of 33
doctors including 8 neonatologists
and pediatric intensive care specialists, 1 neuropediatrician, 3 pediatric surgeons, 4 child psychiatrists
and 17 pediatricians and emergency
care physicians and 9 junior doctors, led by Isabelle Kieffer, head of
the department, performed 30,100
consultations for 12,389 patients.
First point of reference for pediatric emergency in Luxembourg, the
department also dealt with 32,037
emergency visits, an average of 87
visits per day.
Education
With a very experienced team of specialized
doctors, the department attracts numerous
medical students each year from neighboring
countries (Belgium and France) as well as junior doctors. For these students the diversity
of daily patient consulting at the pediatric clinic means encountering a variety of cases and
diseases, which broadens their experience and
expertise. They also appreciate the dedication
and time of the more experienced doctors, supporting them throughout their internships.
Research
Fundamental research focuses on pediatric
endocrinology, with the strong collaboration
of Dr Carine de Beaufort, internationally recognized as the leading expert in the field, with
the Luxembourg Centre for Systems Biomedicine of the University of Luxembourg. The team
mainly works on diabetes, seeking to improve
the short and long term outcomes of children
suffering from this severe chronic disease, with
a focus on their quality of life.
Several clinical projects are also managed
thanks to the collaboration with the LIH Clinical and Epidemiological Investigation Center
(CIEC) and the Integrated Bio Bank Luxembourg (IBBL).
Coordinated by the University of Helsinki and
mainly financed by the National Institutes of
Health (part of the US department of Health
and Human Services) the
Trial to Reduce Insulin Dependent Diabetes
Mellitus in the Genetically at Risk (TRIGR)
was the first multicenter international type 1
diabetes prevention trial to be undertaken. The
Centre Hospitalier de Luxembourg was one of
the 77 centers which took part in the study, aiming to recruit pregnant women matching the
40
research criteria and their newborns for long
term follow up assessment. All over the world,
5,000 mothers and their infants were enrolled
with the aim of testing whether weaning to formula containing hydrolyzed vs. intact cow’s milk
protein would be efficacious in decreasing risk
for development of type 1 diabetes-associated
auto antibodies and type 1 diabetes among infants identified to be at increased risk for diabetes, based on their human leukocyte antigen
profile and family history. Results of the research
have been presented in several articles.
Familial very long chain acyl-CoA dehydrogenase deficiency as a cause of neonatal sudden
infant death: Improved survival by prompt
diagnosis
Scalais E, Bottu J, Wanders RJA, Ferdinandusse S,
Waterham HR, De Meirleir L.
2015. Am J Med Genet Part A 167A:211–214.
Inherited metabolic disorders are the underlying causes of a small but significant number of
neonatal sudden infant deaths. Very Long chain
Acyl-CoA Dehydrogenase (VLCAD) deficiency
is the most common long-chain fatty acid oxidation defect, with a disease prevalence of up
to 1:31,500. Neonatal presentation is often characterized either by hypertrophic or dilated cardiomyopathy, hepatic encephalopathy, or severe
hypoketotic hypoglycemia, or by all three together. We describe a family with repeated neonatal deaths due to VLCAD deficiency, and the clinical evolution of the latest affected sibling.
Joining forces: a call for greater collaboration
to study new medicines in children and adolescents with Type 2 diabetes
Karres J, Pratt V, Guettier JM, Temeck J, Tamborlane
WV, Dunger D, Bejnariu C, De Beaufort C, Tomasi P
2014, Diabetes Care 2014; 37:2665-2667
A collaborative effort will facilitate the collection
of adequate and well-controlled pediatric efficacy and safety clinical trial data to inform pediatric use of new drugs to treat type 2 diabetes. An
approach relying on a multi-arm trial is a particularly attractive one,which leverages efficiencies
gained from use of a shared control group with
efficiencies gained from a shared research infrastructure. Success in pediatric drug development
has often involved collaboration. Indeed, reliance
on consortia-based approaches to evaluate no-
vel therapies was successful for other relatively
uncommon pediatric diseases and should meet
with similar success in type 2 diabetes.
Dr Carine de Beaufort, physician at the CHL is
also the Secretary General of the International
Society for Pediatric and Adolescent Diabetes.
In this capacity, she was invited by Indonesian
health care professionals to give lectures in Jakarta on the most important topics for the care
of children with diabetes. The course, limited
to 40 participants, combined plenary sessions,
fruitful exchanges among teams around theoretical and real case histories, and practical skills
training. A registry was started as a follow-up
of this course to identify children with diabetes.
The creation of this registry led to a more than
tenfold increase in the number of children identified with this disease (now > 1,000), which
suggest that the incidence of the course may
be far higher than expected.
Number of students/
interns and junior
doctors in 2014 :
24
18
Students, of which 4 high
school students who spent
a week at the hospital to
learn about the work of a
specialized doctor
Junior
doctors
13
Articles or contributions
to articles in national and
41
GASTROENTEROLOGY, HEPATOLOGY,
NEPHROLOGY AND ENDOCRINOLOGY
The department of gastroenterology, hepatology, nephrology and endocrinology brings together medical
specialties all dealing with chronic
diseases with heavy impact on public health. The four services mainly perform ambulatory acts, with a
strong focus on therapeutic training
for patients. In 2014, approximately
11,500 consultations were done with
9,600 patients by the medical team
of 9 specialists and 3junior doctors
led by Dr Frédéric Dadoun, head of
the department. The department
accounted for 5,141 days of hospitalization.
Education
Physicians from the department are committed to welcoming students in their 4th to 6th
year of medical studies to provide them with a
practical training in several weeks in 3 sub-specialties of internal medicine. Such trainings are
mandatory in the Belgium and German systems,
and medical students often choose to train at
the department of gastroenterology, hepatology, nephrology and endocrinology at the CHL.
They benefit from the strong medical expertise
of senior physicians and have the opportunity
to be involved in the day-to-day running of their
service, thereby encountering different pathologies and treatments.
Research
Research on endocrinology focuses on body
composition in relation to metabolic diseases of
children and adults and on type 1 diabetes. In
this context, projects have been led on auto-immunity as well as new treatment technologies
in type 1 diabetes. Sharing the same research
interest, endocrinologists have built a strong
relation with pediatrics endocrinologists and
have already collaborated on several research
projects.
leg fat mass may protect against cardiometabolic risks factors in children and adolescents,
especially against insulin resistance and adverse
blood lipid profiles.
Cardiometabolic risk: leg fat is protective during
childhood
Samouda H, De Beaufort C, Stranges S, Hirsch M,
Van Nieuwenhuyse J-P,Dooms G, Gilson G, Keunen O,
Leite S, Vaillant M, Lair M-L, Dadoun F
Pediatric Diabetes 2015
Autoimmune disorders and quadrivalent human papillomavirus vaccination of young female subjects
Atlan C, collaborator in Grimaldi-Bensouda L, Guillemot D, Godeau B, Bénichou J, Lebrun-Frenay C, Papeix C, Labauge P, Berquin P, Penfornis A, Benhamou
PY, Nicolino M, Simon A, Viallard JF, Costedoat-Chalumeau N, Courcoux MF, Pondarré C, Hilliquin P, Chatelus
E, Foltz V, Guillaume S, Rossignol M, Abenhaim L.
PGRx-AID Study Group.
One of the endocrinologists of the Centre Hospitalier de Luxembourg took part in a multicentric
study which investigated whether the quadrivalent human papillomavirus vaccine is associated
with a change in the risk of autoimmune disorders in young female subjects. No evidence of an
increased risk of the most frequent autoimmune
diseases was found following vaccination within
the time period studied.
Obesity and overweight children in Luxembourg
With a total of 250 million children overweight
or obese in the world, childhood obesity is a
major public health concern, as it is associated
with early cardiometabolic risks, increased risk
of adulthood obesity and worse health outcomes. Endocrinologists took part in a study led
by pediatric endocrinologists from the CHL and
researchers from the Luxembourg’s Institute of
Health to investigate the relationship between
leg fat mass and cardiometabolic risk factors
in youth. The study led to the conclusion that,
after taking total body fat mass into account,
42
Physical activity and sport practice has proven
beneficial for the global health and wellbeing of
type 1 diabetes patients, but the fear of hypoglycemia and of glycemic disturbances is an obstacle to regular practice. Together with other
diabetology teams from France, a multicentric
study (DIABRASPORT II) is being set up at the
CHL in order to provide a more accurate guidance to patients, for both insulin dosing and
dietary advices during and after physical activities. It will involve endocrinologists and physiotherapists and should start in 2015. The aim
is to better prevent hypoglycemia and glycemic
disturbances during and after exercise to promote regular physical activity in patients with
type 1 diabetes.
Number of students/
interns and junior
doctors in 2014 :
12
3
Students
Junior doctors (2 of them
as part of their rotation
in “internal medicine”
departments)
3
Articles or contributions
to articles in national and
43
SURGERY (GENERAL, DIGESTIVE, VASCULAR, THORACIC,
ENDOCRINE, HEPATO-GASTROENTEROLOGIC) – UROLOGY
The department regroups two services. The first one deals with general surgery, as well as specialized
surgery for digestive and endocrine
diseases. Surgeons have developed
a strong expertise in minimally invasive surgery, such as laparoscopic
surgery, one of the most efficient
ways to deal with cancer surgery.
The second service is specialized in
urology. More than 9,600 patients
annually consult the team of 7 medical doctors (5 in surgery, 2 in urology) and 5 junior doctors, led by Dr
Martine Goergen, head of the department. In 2014, the department
accounted for 10,889 days of hospitalization.
Education
Thanks to the links built with several Spanish
universities, one to two Spanish junior doctors
have the opportunity every year to spend a
few months in Luxembourg to complete their
training and learn from highly experienced surgeons. Junior doctors coming to Luxembourg
are particularly interested in techniques related
to laparoscopic surgery, in which CHL physicians have extensive expertise.
Research
Fundamental and clinical research in the department focuses on obesity and metabolic surgery,
and on laparoscopy (or minimally invasive surgery) as a major technique in gastric and metabolic surgery. Moreover, surgeons strongly collaborate with cardiologists and oncologists on
research on cancer and cardiovascular diseases.
Fast and best tracks in obesity and metabolic
surgery
The team is currently working on a project on
fast and best tracks in obesity and metabolic surgery, aiming at standardizing and establishing a new pathway in obesity and metabolic surgery, with the ultimate goal of improving
outcomes and diminishing costs. More than 100
patients were included last year. Preliminary
analysis indicates that fast-track in bariatric surgery can indeed reduce hospital costs, in terms
of infrastructure investment, but also regarding
the length of patient’s stay in the hospital. Physicians also realized how essential the information given to patients is. As a consequence they
support a multidisciplinary consultation with all
members of the medical and health care team,
to improve coordination and communication
among colleagues, and ultimately the care of
the patient.
44
Imigastric - establishing a Multi-Institutional
registry to compare the outcomes of robotic, laparoscopic and open surgery for Gastric
Cancer
Physicians from the CHL are taking part in a
multicenter study led by the University of Perugia, to compare the outcomes of robotic, laparoscopic and open surgery for gastric cancer.
Gastric cancer represents a great challenge for
health care providers and requires a multidisciplinary management in which surgery plays a
main role. Minimally invasive surgery has been
progressively developed, first with the advent of
laparoscopy and more recently with the use of
the robotic system. A number of issues are currently being debated, including the limitations
in performing effective extended lymph node
dissections and, in this context, the real advantages of using robotic systems, the possible role
for advanced gastric cancer, the reproducibility of total intracorporeal techniques and the
oncological results achievable during longterm
followup. IMIGASTRIC, a multiinstitutional project, aims at creating the most extensive international database in existence of patients receiving distal, subtotal or total gastrectomy using
the robotic, laparoscopic or open approach
performed at institutions with experience in
gastric and minimally invasive surgery. Analysis
of the data collected will allow researchers to
determine the long and short term surgical and
clinical outcomes and to compare the results
according to the type of intervention and surgical approaches.
Minimally invasive management of postoperative esophagojejunal anastomotic leak
Facy O, Goergen M, Poulain V, Heieck F, Lens V, Azagra JS.
Surg Laparosc Endosc Percutan Tech. 2014 Apr.
Between 2003 and 2011, 38 patients underwent
laparoscopic total gastrectomy and 2 developed an esophagojejunal fistula.The diagnosis
was established by a computed tomography
scan with contrast ingestion. The absence of
complete dehiscence and the vitality of the alimentary loop were checked during laparoscopic exploration, associated with effective drainage. During the endoscopy, dehiscence was
assessed and a covered stent and nasojejunal
tube were inserted for enteral feeding. The leaks
healed progressively, oral feeding was resumed
and the drains removed within 3 weeks. The
stent was removed after 6 weeks. Three months
later, the patients were able to eat without dysphagia. Early diagnosis allows for successful
conservative management. The objectives are
effective drainage, covering by an endoscopic
stent and renutrition. Management by a multidisciplinary team is essential.
Two of the highly experienced surgeons of the
department, Dr Martine Goergen and Dr Juan
Santiago Azagra lately received high distinctions; Dr Goergen has been appointed European professional mediator as well as member
of the administration council of the Foundation
Kribskrank Kanner and Dr Azagra was recognized as an honored member of the French
Surgery Academy.
Number of students/
interns and junior
doctors in 2014 :
10
5
25
Junior doctors
Visiting doctors
Students
5
Articles or
contributions to
articles in national and
45
MEDICAL IMAGING
The department of medical imaging
provides a full range of imaging and
therapeutic services, with specific
expertise in pediatric radiology, neuroradiology, mammography, nuclear
medicine and interventional radiology (utilization of minimally invasive
image-guided procedures to diagnose and treat diseases in nearly
every organ system). In 2014, the department performed 178,248 images,
and 68,468 patients consulted the
team of 14 radiologists and neuroradiologists and 4 junior doctors, led by
Dr Vincent Lens, head of the department.
Education
Primary aortic thrombosis: role of enhanced
multislice CT demonstrated in three exceptional cases
Verbeeck N, Cavez N, Plawny L, Weber J, Lens V.
JBR-BTR. 2014 Mar-Apr; 97(2):76-80.
train medical students and junior doctors pursuing their specialization each year.
Research
Research in the department mostly focuses on
technical aspects of radiology and on the different techniques and devices used. Radiologists are also often co-investigators of studies
or researches done by other specialists and
services (neurology, oncology, cardiology, and
orthopedics to mention a few). The images they
realize are a strong support to the assessment
and analysis done in clinical as well as fundamental research projects.
Primary aortic thrombosis remains a rare entity
that can be defined as clotting of the vessel without any obvious atheromatous lesion. Cancer
chemotherapy, cocaine intake, essential thrombocythemia, some hypercoagulable states, heparin-induced thrombocytopenia, inflammatory
disease of the digestive tract and acute pancreatitis are, beside some cases of rather unknown
etiology, the causes of primary aortic thrombosis. Intravenous contrast-enhanced multislice CT,
which is widely available, noninvasive and affordable in terms of cost, is the imaging modality
of choice for the investigation of primary aortic thrombosis and the assessment of potential
complications. Three cases due to chemotherapy, antiphospholipid syndrome and acute pancreatitis are reported.
Radioinduced brain cyst: case report
Dooms G, Molitor P, Boulanger T, Hana A, Standhardt H, Hertel F, Lovblad KO.
Bull Soc Sci Med Grand Duche Luxemb.2014 ;(1):15-25
Physicians from the CHL present a case of intraparenchymal radioinduced cyst of the brain
observed in our department. It is a rare and relatively benign pathology which is usually treated conservatively or by surgery. We emphasize
long-term imaging follow up in patients treated
by radiosurgery, which can lead to the demonstration of multiple adverse events such as tumefactive cyst formation.
Neuroradiologists from the CHL are taking part
in a new research project led by the Centre François Baclesse, Luxembourg’s national center of
radiotherapy. This new observational study aims
at assessing the possibility of cerebral necrosis
after stereotaxic radiotherapy of metastasis. It
also intends to assess the clinical, radiological
and dosimetric incidences. The project started
in 2014, with results expected in 2016 and a publication to follow. It will help demonstrate the
importance of focused treatments of cerebral
metastasis, as well as assessing the efficiency of
operations via cyber knife.
Observational and prospective study of cerebral
necrosis after stereotaxic radiotherapy of metastasis
Number of students
and MEVS in 2014 :
3
Students
8
Junior
doctors
Antoni D, Dooms G, Van Haver T, Paulus P, Untereiner M, Nickers P.
18
46
Articles or
contributions to
and international
journals
47
HEALTHCARE
The role of strength exercises in the rehabilitation of muscle dysfunction in chronic heart
failure
Health care encompasses all activities related to the health of patients
and not performed by medical doctors. Nurses, nutrition therapists,
psychologists, physical therapists
are all health care professionals,
essentials to the functioning of the
hospital and the best of care for
patients. These professionals represent a workforce of more than
1,300 people at the Centre Hospitalier de Luxembourg.
Patrick Feiereisen, Physical Therapist
Education
Chronic heart failure induces a decrease of
blood flow to peripheral muscle, leading to
muscular atrophy. This muscle atrophy plays a
major part in patient symptoms: exercise intolerance, fatigue, breathing difficulties. The aim
of the study was to identify which training programs could prevent these peripheral muscular
dysfunctions most efficiently. A strong emphasis was put on strengthening exercise, a training
method seldom used in the rehabilitationof
patients with chronic heart failure at the start
of the study. Recognizing the importance of the
study and the results achieved at the CHL, international guidelines are nowadays acknowledging the importance of strengthening exercises
as an integral part of the rehabilitation of patient with chronic heart failure, partly thanks to
the results of the research done at the CHL.
Visions of geriatrics at the Centre Hospitalier
de Luxembourg
Frédéric Mennel, Nurse
Aging is a public health challenge involving the
creation of specialized services and the adaptation of current structures to answer the specific needs of elderly people. This study aims
at better understanding the challenges facing
health care professionals in their adaptation to
an aging population.
How to evaluate and deal with child pain
Angélique Gallo, Nurse in anesthesia and Valérie
Loutsch, Pediatric Nurse
The objective of the study was to design a
method of evaluation of pain in children, which
could be used in all pathologies and would bring
new possibilities to help deal with the pain. This
study contributed to the improvement of the
relation between children in pain and their parents.
Training and supporting the education of young
professionals is of paramount importance for
all CHL departments and services in charge of
health care. In 2014, the nursing department
organized more than 1,000 internships, ranging
from jobshadowing for high school pupils, to
nursing observation internships for students,
either in nursing school and aiming at becoming
a nurse, or in their first year of medical studies.
Acknowledging the quality of the training provided, several formal agreements have been signed with Luxembourgish and Belgian nursing
schools. The physical therapy unit is also strongly involved in training, welcoming 83 students
in 2014, mainly thanks to the close links established with some Belgian Institutions and Universities for physical therapy.
Research
48
Realizing the importance of clinical research
for improving the quality of care and services
given to the patients, healthcare services and
departments are increasing their involvement
in research projects and activities. Thanks to
the support given by the direction of the CHL
to professionals willing to pursue their studies
and projects, 35 research works were presented
in 2014, from dissertations to theses or student
papers.
49
publications
Academic titles
chapters in books
presentations at
congresses
50
51
publications
52
Name
Name
Service
Service
Title
Title
Abou Hamdan
Kamal
Pneumologie
Asthma and smoking: a dangerous mix
Charpentier-Chaix C, Abou Hamdan K, Wirtz G, Morisset M, Schlesser M
Le Courrier des Addictions 2014 Jan; 1
Abou Hamdan
Arendt
Kamal
Victor
in Frentz D, Van de Vijver DA, Abecasis AB, Albert J, Hamouda O,
Jørgensen
Kücherer
Struck
D, Schmit
JC, Vercauteren
J, Åsjö
in Frentz D,LB,
Van
de VijverC,DA,
Abecasis
AB, Albert
J, Hamouda
O, B,
Balotta
C, Beshkov
D, Camacho
RJ,
B,JC,
Coughlan
S, Griskevicius
Jørgensen
LB, Kücherer
C, Struck
D,Clotet
Schmit
Vercauteren
J, Åsjö B, A,
Grossman
Z, HorbanD,A,
Kolupajeva
Korn B,
K, Coughlan
Kostrikis LG,
Liitsola K, A,
Balotta C, Beshkov
Camacho
RJ, T,
Clotet
S, Griskevicius
Linka
M, Nielsen
C, Otelea
D, Paraskevis
D, Paredes
R, Poljak
M,
Grossman
Z, Horban
A, Kolupajeva
T, Korn
K, Kostrikis
LG, Liitsola
K,
Puchhammer-Stöckl
E, Sönnerborg
A, Stanekova
D,R,
Stanojevic
Linka M, Nielsen C, Otelea
D, Paraskevis
D, Paredes
Poljak M, M, Van
Wijngaerden
E, Wensing
AM, Boucher
CA; SPREAD
Puchhammer-Stöckl
E, Sönnerborg
A, Stanekova
D, Programme.
Stanojevic M, Van
2,56
Victor
Increase in transmitted resistance to non-nucleoside reverse transcriptase
inhibitors
newly resistance
diagnosedto
HIV-1
infections inreverse
Europe.transcriptase
Increase inamong
transmitted
non-nucleoside
BMC Infect Dis. 2014 Jul 21;14:407
Arendt
Pneumologie
Maladies
Infectieuses
Maladies
2,56
Arendt
Victor
Patterns of transmitted HIV drug resistance in Europe vary by risk group
PLoS One. 2014 Apr 10;9(4):e94495
3,53
Arendt
Victor
Maladies
Infectieuses
Maladies
PLoS One. 2014 Apr 10;9(4):e94495
3,53
Arendt
Victor
AIDS. 2014 Sep 24;28(15):2329-31
6,55
Victor
Virological and immunological outcomes of elvitegravir-based regimen in a
treatment-naïve
HIV-2-infectedoutcomes
patient of elvitegravir-based regimen in a
Virological and immunological
Boucher C, Wensing A; SPREAD Programme
Zheng Y, Lambert C, Arendt V, Seguin-Devaux C
Arendt
Maladies
Infectieuses
Maladies
AIDS. 2014 Sep 24;28(15):2329-31
6,55
Azagra
Juan S.
Juan S.
Bache
Manon
générale
Néonatologie
Surg Laparosc Endosc Percutan Tech.
2014
Apr;24(2):183-6
Surg Laparosc
Endosc Percutan Tech.
0,93
Azagra
Bache
Manon
Néonatologie
Backes
François
Traumatologie
Backes
François
Traumatologie
Backes
François
Traumatologie
Backes
François
Traumatologie
Beissel
Jean
Cardiologie
Beissel
Jean
Cardiologie
Berchem
Guy
Berchem
Guy
HématologieCancérologie
Hématologie-
Berchem
Guy
Berchem
Guy
Berchem
Guy
Berchem
Guy
Berchem
Guy
Berchem
Guy
Berchem
Guy
Berchem
Guy
Berchem
Guy
Berchem
Guy
Berchem
Guy
Berchem
Guy
Berchem
Guy
Berchem
Guy
Infectieuses
Infectieuses
Infectieuses
Chirurgie
générale
Chirurgie
Cancérologie
Hématologie-
Cancérologie
inhibitors among newly diagnosed HIV-1 infections in Europe.
treatment-naïve HIV-2-infected patient
Minimally invasive management of postoperative esophagojejunal
anastomotic
leak management of postoperative esophagojejunal
Minimally invasive
anastomotic leak
Effects of pre-feeding oral stimulation on oral feeding in preterm infants: a
randomized
clinical trial.
Effects of pre-feeding
oral stimulation on oral feeding in preterm infants: a
randomized clinical trial.
Iliopubic subcutaneous plate osteosynthesis for osteoporotic fractures of
the
anterior
pelvic ring. plate
An alternative
to the for
supra-acetabular
external of
Iliopubic
subcutaneous
osteosynthesis
osteoporotic fractures
fixator.
the anterior pelvic ring. An alternative to the supra-acetabular external
fixator.
the
anterior
pelvic ring. plate
An alternative
to the for
supra-acetabular
external of
Iliopubic
subcutaneous
osteosynthesis
osteoporotic fractures
fixator.
fixator.
Cardiovascular health: a cross-national comparison between the Maine
Syracuse
Study health:
(Central
York, USA)
and ORISCAV-LUX
Cardiovascular
a New
cross-national
comparison
between(Luxembourg).
the Maine
Syracuse Study (Central New York, USA) and ORISCAV-LUX (Luxembourg).
Autophagic degradation of GZMB/granzyme B: a new mechanism of
hypoxic
tumor
cell escape
natural killer cell-mediated
lysis of
Autophagic
degradation
offrom
GZMB/granzyme
B: a new mechanism
hypoxic tumor cell escape from natural killer cell-mediated lysis
Autophagy: an adaptive metabolic response to stress shaping the
antitumor
immunity
Autophagy:
an adaptive metabolic response to stress shaping the
antitumor immunity
BAG6/BAT3 modulates autophagy by affecting EP300/p300 intracellular
localization.
localization.
Hématologie-
BAT3 modulates p300-dependent acetylation of p53 and autophagyrelated
protein 7 p300-dependent
(ATG7) during autophagy
BAT3 modulates
acetylation of p53 and autophagy-
Hématologie-
Bronchial airway gene expression in smokers with lung or head and neck
cancer
Hématologie-
Disruption of autophagy by the histone deacetylase inhibitor MGCD0103
and
its therapeutic
implication
B-cell chronic
lymphocytic
Disruption
of autophagy
by thein
histone
deacetylase
inhibitorleukemia
MGCD0103
Cancérologie
Cancérologie
Cancérologie
related protein 7 (ATG7) during autophagy
cancer
and its therapeutic implication in B-cell chronic lymphocytic leukemia
First-line crizotinib versus chemotherapy in ALK-positive lung cancer.
Two biomarker-directed randomized trials in European and Chinese
patients
with nonsmall-cell
lung cancer:
theinBRCA1-RAP80
Two biomarker-directed
randomized
trials
European and Expression
Chinese
Customization
(BREC) studies.
patients with nonsmall-cell
lung cancer: the BRCA1-RAP80 Expression
Customization (BREC) studies.
Authors
Authors
Wijngaerden E, Wensing AM, Boucher CA; SPREAD Programme.
in Frentz D, van de Vijver D, Abecasis A, Albert J, Hamouda O,
Jørgensen
Kücherer
C, Struck
D, Schmit
JC, Vercauteren
in Frentz D,L,van
de Vijver
D, Abecasis
A, Albert
J, HamoudaJ,O,Asjö B,
Balotta
C, Bergin
C, Beshkov
D, Camacho
Clotet
B, Griskevicius
Jørgensen
L, Kücherer
C, Struck
D, SchmitR,
JC,
Vercauteren
J, Asjö A,
B,
Grossman
Z, Horban
A, Kolupajeva
T, KornR,K,Clotet
Kostrikis
L, Linka KL, A,
Balotta C, Bergin
C, Beshkov
D, Camacho
B, Griskevicius
Nielsen
C, Otelea
D, Paraskevis
D, Paredes
M, PuchhammerGrossman
Z, Horban
A, Kolupajeva
T, Korn R,
K, Poljak
Kostrikis
L, Linka KL,
Stöckl
A, Stanekova
D, Stanojevic
M, M,
Vandamme
AM,
NielsenE,C,Sönnerborg
Otelea D, Paraskevis
D, Paredes
R, Poljak
PuchhammerBoucher
Wensing A;
Programme
Stöckl E, C,
Sönnerborg
A,SPREAD
Stanekova
D, Stanojevic M, Vandamme AM,
Publication /Reference
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Factor
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2014
Factor
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2014
0,93
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Early Hum Dev. 2014 Mar;90(3):125-9
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1,93
Bull Soc Sci Med Grand Duche Luxemb.
2014;(1):7-14.
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Crichton GE, Elias MF, Davey A, Sauvageot N, Delagardelle C, Beissel J,
Alkerwi
CrichtonA.GE, Elias MF, Davey A, Sauvageot N, Delagardelle C, Beissel J,
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BMC Public Health. 2014 Mar 15;14:253
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Alkerwi A.
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2,32
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11,42
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11,42
Viry E, Paggetti J, Baginska J, Mgrditchian T, Berchem G, Moussay E,
Janji
B Paggetti J, Baginska J, Mgrditchian T, Berchem G, Moussay E,
Viry E,
Biochem Pharmacol. 2014 Nov 1;92(1):
31-42
4,65
Janji B
Sebti S, Prébois C, Pérez-Gracia E, Bauvy C, Desmots F, Pirot N, Gongora
C, Bach
AS, Hubberstey
AV, Palissot
V, Berchem
G, Codogno
Sebti
S, Prébois
C, Pérez-Gracia
E, Bauvy
C, Desmots
F, Pirot P,
N,Linares
Gongora
LK,
Liaudet-Coopman
E,AV,
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AS, Hubberstey
PalissotS V, Berchem G, Codogno P, Linares
LK, Liaudet-Coopman E, Pattingre S
C,
Bach
AS, Hubberstey
AV, Palissot
V, Berchem
G, Codogno
Sebti
S, Prébois
C, Pérez-Gracia
E, Bauvy
C, Desmots
F, Pirot P,
N,Linares
Gongora
LK,Bach
Liaudet-Coopman
E,AV,
Pattingre
C,
AS, Hubberstey
PalissotS.V, Berchem G, Codogno P, Linares
LK, Liaudet-Coopman E, Pattingre S.
Van Dyck E, Nazarov PV, Muller A, Nicot N, Bosseler M, Pierson S, Van
Moer
K, Palissot
V, Mascaux
C, Knolle
U, Ninane
V, Nati
Bremnes
RM,
Van Dyck
E, Nazarov
PV, Muller
A, Nicot
N, Bosseler
M, R,
Pierson
S, Van
Vallar
L, Palissot
BerchemV,G,
Schlesser
M.
Moer K,
Mascaux
C, Knolle
U, Ninane V, Nati R, Bremnes RM,
Vallar L, Berchem G, Schlesser M.
El-Khoury V, Pierson S, Szwarcbart E, Brons NH, Roland O, Cherrier-De
Wilde
S, Plawny
L, Van
E, Berchem
G NH, Roland O, Cherrier-De
El-Khoury
V, Pierson
S, Dyck
Szwarcbart
E, Brons
Wilde S, Plawny L, Van Dyck E, Berchem G
in Solomon BJ, Mok T, Kim DW, Wu YL, Nakagawa K, Mekhail T, Felip E,
Cappuzzo
Paolini
T, Iyer
Reisman
A, Wilner
KD, Tursi
J, E,
in SolomonF,BJ,
Mok J,
T, Usari
Kim DW,
WuS,YL,
Nakagawa
K, Mekhail
T, Felip
Blackhall F;F,PROFILE
Cappuzzo
Paolini J,1014
UsariInvestigators.
T, Iyer S, Reisman A, Wilner KD, Tursi J,
Blackhall F; PROFILE 1014 Investigators.
in Moran T, Wei J, Cobo M, Qian X, Domine M, Zou Z, Bover I, Wang L,
Provencio
YuJ,L,Cobo
ChaibM,
I, Qian
You C,
in Moran T,M,
Wei
X,Massuti
DomineB,M,Song
Zou Y,
Z, Vergnenegre
Bover I, WangA,L,Lu
H,
Lopez-Vivanco
Hu W,
Robinet
G, YanB,
J, Song
Insa A,
X, Majem M,
Provencio
M, Yu L,G,
Chaib
I, You
C, Massuti
Y, Xu
Vergnenegre
A, Lu
Chen
X, de Las Peñas
R, W,
Karachaliou
Sala
Q, X,
IslaMajem
D, Zhou
H,
Lopez-Vivanco
G, Hu
Robinet G,N,Yan
J, MA,
InsaWu
A, Xu
M, Y,
4,65
31-42
Autophagy. 2014 Jul;10(7):1341-2.
11,42
Autophagy. 2014 Jul;10(7):1341-2.
11,42
Proc Natl Acad Sci U S A. 2014 Mar
18;111(11):4115-20
9,80
18;111(11):4115-20
9,80
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Cancer Med. 2014 Apr;3(2):322-36
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9,37
Leukemia. 2014 Aug;28(8):1636-46
9,37
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54,42
N Engl J Med. 2014 Dec 4;371(23):2167-77
54,42
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6,57
Ann Oncol. 2014 Nov;25(11):2147-55
6,57
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BAT3 modulates p300-dependent acetylation of p53 and autophagyrelated protein 7 (ATG7) during autophagy
C, Bach AS, Hubberstey AV, Palissot V, Berchem G, Codogno P, Linares
18;111(11):4115-20
Berchem
Guy
cancer
Cancer Med. 2014 Apr;3(2):322-36
Surname
Name
Service
Title
Moer K, Palissot V, Mascaux C, Knolle U, Ninane V, Nati R, Bremnes RM,
Guy
Pneumologie
Leukemia. 2014 Aug;28(8):1636-46
Cappuzzo F, Paolini J, Usari T, Iyer S, Reisman A, Wilner KD, Tursi J,
Jørgensen LB, Kücherer C, Struck D, Schmit JC, Vercauteren J, Åsjö B,
Balotta C, Beshkov D, Camacho RJ, Clotet B, Coughlan S, Griskevicius A,
Grossman
Horban
A, Kolupajeva
T, Korn K,
LG, Liitsola
in Moran T,Z,
Wei
J, Cobo
M, Qian X, Domine
M, Kostrikis
Zou Z, Bover
I, WangK,L,
Linka
M, Nielsen
C, Chaib
OteleaI, D,
Paraskevis
D,B,
Paredes
Poljak M,
Provencio
M, Yu L,
You
C, Massuti
Song Y,R,Vergnenegre
A, Lu
Puchhammer-Stöckl
E, Sönnerborg
A, Yan
Stanekova
M,M,
Van
H, Lopez-Vivanco G, Hu
W, Robinet G,
J, Insa D,
A, Stanojevic
Xu X, Majem
Wijngaerden
E, Peñas
Wensing
AM, BoucherN,CA;
SPREAD
Chen X, de Las
R, Karachaliou
Sala
MA, WuProgramme.
Q, Isla D, Zhou Y,
N Engl J Med. 2014 Dec 4;371(23):2167-77
54,42
2,56
Ann Oncol. 2014 Nov;25(11):2147-55
6,57
PLoS One. 2014 Apr 10;9(4):e94495
3,53
Biomed Tech 2014; 59 (s1) © 2014 by
Walter de Gruyter Boston. DOI 10.1515/
bmt-2014-4254
1,23
publications
Berchem
Authors
9,80
Impact
Factor
2014
9,37
Abou Hamdan
Kamal
Berchem
Arendt
Guy
Victor
HématologieMaladies
Cancérologie
Infectieuses
Berchem
Guy
patients with nonsmall-cell lung cancer: the BRCA1-RAP80 Expression
Arendt
Victor
Maladies
Infectieuses
Bernard
Florian
Neurochirurgie
Improving the Consistency of Manual Deep Brain Structure Segmentations
by Combining Variational Interpolation, Simultaneous Multi-Modality
Visualisation and Histogram Equilisation
Arendt
Bernard
Victor
Florian
Maladies
Neurochirurgie
Infectieuses
Virological
outcomes
of elvitegravir-based
regimen
Influence ofand
theimmunological
electrode-electrolyte
interface
on the electric field
in in a
treatment-naïve
HIV-2-infected patient
Deeob Brain Stimulation.
Zheng
Lambert
C,F,Arendt
C P, Koch P, Hertel F
BremmY,RP,
Bernard
HuschV,
A,Seguin-Devaux
Neb H, Gemmar
AIDS.
2014
Sep
24;28(15):2329-31
Biomed
Tech
2014;
59 (s1)
6,55
1,23
Azagra
Berthold
Juan
S.
Christophe
Chirurgie
Neurochirurgie
générale
Minimally
management
postoperative
esophagojejunal
DTI of the invasive
visual pathway
- whiteof
matter
tracts and
cerebral lesions
anastomotic leak
Facy
PoulainVR,
V, Heieck
F, Lens
V, Azagra
JS.
Hana O,
A, Goergen
Husch A, M,
Gunness
Berthold
C, Dooms
G, Boecher
Schwarz
H, Hertel F
Surg
Percutan Tech.
J Vis Laparosc
Exp. 2014Endosc
Aug 26;(90).
2014 Apr;24(2):183-6
0,93
Bache
Berthold
Manon
Christophe
Néonatologie
Neurochirurgie
Effects
of pre-feeding
oral
stimulation on oral feeding
preterm
a
NOAC and
intracerebral
bleeding--presentation
of fourincases
and infants:
review of
randomized
the literatureclinical trial.
Bache
Pizon E, C,
Jacobs
J, Vaillant
M, Lecomte
A
Hana A,M,Berthold
Gunness
VR, Dooms
G, Standhardt
H, Koy J, Matgé
G, Boecher-Schwarz H, Hertel F.
Early
Hum
Mar;90(3):125-9
Bull Soc
SciDev.
Med2014
Grand
Duche Luxemb.
2014;(1):57-66
1,93
Backes
Berthold
François
Christophe
Traumatologie
Neurochirurgie
Gerich
T, VR,
Bogdan
F, Gillman
T, Seil
R, Pape
Gunness
HanaA,A,Backes
Berthold
C, Dooms
G, Hertel
F D.
Bull
Bull Soc
Soc Sci
Sci Med
Med Grand
Grand Duche
Duche Luxemb.
Luxemb.
2014;(1):7-14.
2014;(3):25-30.
BoecherBackes
Schwarz
Hans
François
Neurochirurgie
Traumatologie
Hana A, Husch A, Gunness VR, Berthold C, Hana A, Dooms G, Boecher
Gerich
T, H,
Bogdan
Schwarz
HertelA,
F Backes F, Gillman T, Seil R, Pape D
BoecherSchwarz
Beissel
Bogdan
Hans
Neurochirurgie
Jean
Oana-Alina
Cardiologie
Traumatologie
Berchem
Guy
J Vis Exp. 2014 Aug 26;(90).
2014;(1):7-14
2014;(1):57-66
2014;(1):7-14
Autophagy. 2014 Jan;10(1):173-5
Bogdan
Berchem
Alina
Guy
Traumatologie
Iliopubic
plate osteosynthesispatient
for osteoporotic fractures of
Posterior subcutaneous
fossa mass in immunosuppressed
fixator.
DTI of the visual pathway - white matter tracts and cerebral lesions
fixator.
NOAC and intracerebral bleeding--presentation of four cases and review of
the literature.
Syracuse
Study (Centralplate
New osteosynthesis
York, USA) and for
ORISCAV-LUX
Iliopubic subcutaneous
osteoporotic(Luxembourg).
fractures of
Autophagic
degradation
of
GZMB/granzyme
B:
a
new
mechanism
of
fixator.
Autophagy:
adaptive
metabolic
response
stress shaping the
the anterior an
pelvic
ring. An
alternative
to the to
supra-acetabular
external
antitumor
immunity
fixator.
Janji B
Biochem
Pharmacol. 2014 Nov 1;92(1):
2014;(1):7-14
31-42
4,65
Berchem
Bottu
Guy
Jean
HématologieNéonatologie
Cancérologie
BAG6/BAT3
by affecting EP300/p300
intracellular
Familial verymodulates
long chain autophagy
acyl-CoA dehydrogenase
deficiency as
a cause of
localization.
neonatal sudden infant death: Improved survival by prompt diagnosis
Autophagy.
2014 A.
Jul;10(7):1341-2.
Am J Med Genet
2015 Jan;167(1):211-4
11,42
2,04
Boulanger
Berchem
Thierry
Guy
Cavez
Nicolas
Neuroradiologie
Radiologie
Berchem
Chapusette
Guy
Rudy
Radiologie
Moer
K, Palissot
V, Mascaux
Knolle
U, Ninane
V, Nati C,
R, Huybrechts
Bremnes RM,
Dedeken
L, Chapusette
R, LêC,PQ,
Heijmans
C, Devalck
S,
Vallar
L, Berchem
G, Schlesser
Ziereisen
F, Hanssens
L, Rozen M.
L, Noubouossie D, Mujinga MN, Ferster A
Cancer Med. 2014 Apr;3(2):322-36
PLoS One. 2014 Oct 2;9(9):e108922
Berchem
CharpentierChaix
Berchem
CharpentierChaix
Guy
Catherine
Pneumologie
Radioinduced brain cyst: case report.
Primary aortic thrombosis: role of enhanced multislice CT demonstrated in
three exceptional cases
cancer
Reduction of the six-minute walk distance in children with sickle cell
disease is correlated with silent infarct: results from a cross-sectional
evaluation in a single center in Belgium
and
its therapeutic
implication
in B-cell
Asthma
and smoking:
a dangerous
mix chronic lymphocytic leukemia
Sebti
S,E,
Prébois
C, Wanders
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Droogenbroeck J, Vermylen C, Voglova J, Xicoy B, Welte K.
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in
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Brogaard T,Z,Villanueva
Abela J, Eychmuller
MitchellLG,
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A, Lynch
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NH, Roland O, Cherrier-De
Gunness VR, Hana A, Berthold C, Dooms G, Hertel F.
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in Mocroft A, Reiss P, Rakhmanova A, Banhegyi D, Phillips AN, De Wit S,
Ristola M, Lundgren JD, Grarup J, Kirk O; EuroSIDA in EuroCOORD.
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Kamal
Florence E, Ormaasen V, Kirk O, Lundgren JD; EuroSIDA in EuroCOORD
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LB,
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Stanekova
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Grossman Z, Horban E,
A, Sönnerborg
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Wijngaerden
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Increased incidence of antiretroviral drug discontinuation among patients
with viremic hepatitis C virus coinfection and high hyaluronic acid, a marker
of liver fibrosis
AIDS. 2014 Feb 20;28(4):577-87
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Azagra
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Juan S.
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Increased risk of cardiovascular disease (CVD) with age in HIV-positive
men: a comparison of the D:A:D CVD risk equation and general population
Virological
and immunological outcomes of elvitegravir-based regimen in a
CVD risk equations
Letter to the editor: management of patients with Ebola virus disease in
Minimally
invasive management
postoperative
esophagojejunal
Europe: high-level
isolation unitsof
should
have a key
role.
anastomotic leak
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Maladies
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générale
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Néonatologie
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Traumatologie
fixator.
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Prognostic value of vitamin D level for all-cause mortality, and association
with inflammatory markers, in HIV-infected persons
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Thrombocytopenia is associated with an increased risk of cancer during
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Immuno-virological discordance and the risk of non-AIDS and AIDS events
in a large observational cohort of HIV-patients in Europe
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Trends in underlying causes of death in people with HIV from 1999 to 2011
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localization.
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ImmunoHématologieAllergologie
Cancérologie
Correlation of clinical monosensitivity to cod with specific IgE to enolase
BAT3 modulates p300-dependent acetylation of p53 and autophagyand aldolase
related protein 7 (ATG7) during autophagy
Hentges
François
Berchem
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Hentges
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ImmunoAllergologie
Immuno-
Fish allergens at a glance: variable allergenicity of parvalbumins, the major
fish allergens
cancer
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François
Berchem
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C, Rockstroh
Beshkov D,JK,
Camacho
R, Mitsura
Clotet B,
Griskevicius
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D, Bergin
Peters L,
de Wit S,
VM,
Knysz B, A,
Grossman
Z,Kirk
Horban
A, Kolupajeva
T, KornA;
K, EuroSIDA
Kostrikis L,
KL,
Pedersen C,
O, Lundgren
JD, Mocroft
inLinka
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C, Wensing
A; SPREAD
Programme
in Petoumenos
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P, Ryom L,
Rickenbach M, Sabin CA, El-Sadr W,
d'Arminio Monforte A, Phillips AN, De Wit S, Kirk O, Dabis F, Pradier C,
Zheng
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Arendt
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MG;
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de Wit S, Law M, el Sadr W, Kirk O, Friis-Moller N, Monforte Ad, Phillips
AN, Sabin CA, Lundgren JD; D:A:D Study Group
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HématologieImmunoCancérologie
Allergologie
Disruption
of autophagy
by theMammalian
histone deacetylase
Immune responses
to inhalant
allergens inhibitor MGCD0103
El-Khoury
PiersonC,
S,Arumugam
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Hentges F,V,
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Les facteurs
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d'allergie
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Sleiman M, Brons NH, Kaoma T, Dogu F, Villa-Forte A, Lenoble P,
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T, Kotsch
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InsaA,
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Baize N, Zhang F, Garde J, Germonpre P, Rauh S, ALHusaini H, SanchezRonco M,
JJ, Camps C,
B, Rosell
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Golebiewska A,
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N,
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Two
biomarker-directed
randomized
trials in European and Chinese
strongly
modulated by HLA
class I molecules
Customization
(BREC)
studies.
DTI of the visual
pathway
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Gemmar
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Glioblastomas are composed of genetically divergent clones with distinct
tumourigenic potential and variable stem cell-associated phenotypes
Improving
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Deep Brain
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Holmes
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with
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Immune responses to inhalant Mammalian allergens
Hentges F, Léonard C, Arumugam K, Hilger C
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Hentges
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Kamal
NK cell killer Ig-like receptor repertoire acquisition and maturation are
strongly modulated by HLA class I molecules
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Hentges F, Kotsch K, Gadola SD, Vilches C, Zimmer J.
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Neurochirurgie
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Frank
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L, Lenkiewicz
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Grossman
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Kolupajeva
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Influence of the electrode-electrolyte interface on the electric field in
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NOAC and intracerebral
bleeding--presentation
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reviewinofa
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and immunological
outcomes of elvitegravir-based
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Minimally
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anastomotic leak
Gunness
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Orthopédie
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Neurochirurgie
Radiologie
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ImmunoAllergologie
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international multicenter study
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4,12
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2014
Abou Hamdan
Kamal
Pneumologie
Ortega-Cubero S, Lorenzo-Betancor O, Lorenzo E, Agúndez JA,
Jiménez-Jiménez FJ, Ross OA, Wurster I, Mielke C, Lin JJ, Coria F,
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Krüger R, Pastor MA, Pastor P.
Lehners
Arendt
Christiane
Victor
ImmunoMaladies
Allergologie
Infectieuses
Lens
Vincent
Radiologie
anastomotic leak.
Lens
Vincent
Radiologie
Open wedge osteotomy of the tibial head. Management of vascular
complications.
Arendt
Lens
Victor
Vincent
Maladies
Radiologie
Infectieuses
Patterns
of transmitted
HIVrole
drug
Europe vary
by risk group in
Primary aortic
thrombosis:
ofresistance
enhancedin
multislice
CT demonstrated
Maazoun
Yamen
Cardiologie
Percutaneous aortic valve replacement using the Direct Flow Medical
system: results of the Luxembourg registry.
Matgé
Guy
Neurochirurgie
Arendt
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Victor
Xavier
Azagra
Juan S.
Metz
Bache
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Manon
Maladies
Chirurgie
Infectieuses
générale
Chirurgie
générale
Neurologie
Néonatologie
Mocanu
Backes
Mocanu
Iulia
François
Iulia
Radiologie
Traumatologie
Radiologie
Backes
Morel
François
Fanny
Traumatologie
ImmunoAllergologie
the literature.
Comparative Doppler
flow measurements
of the ulnar artery and of the
treatment-naïve
HIV-2-infected
patient
postanastomotic radial artery in radiocephalic arteriovenous fistulas to
detect steal
syndromes
Minimally
invasive
management of postoperative esophagojejunal
anastomotic leak
factors. of pre-feeding oral stimulation on oral feeding in preterm infants: a
Effects
Acute renal failure due to bilateral ureteral stone: a rare occurrence
Comparative
Doppler
flow
of the
ulnar artery and
of the
the
anterior pelvic
ring.
An measurements
alternative to the
supra-acetabular
external
fixator.
detect steal syndromes
Les anterior
facteurs pelvic
de risque
alimentaire
l'adulte.
the
ring.d'allergie
An alternative
to thechez
supra-acetabular
external
fixator.
Morisset
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Jean
ImmunoCardiologie
Allergologie
Morisset
Berchem
Martine
Guy
Morisset
Berchem
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Camacho
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B, Coughlan
Facy O, C,
Goergen
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Poulain
V, Heieck
F, Lens
V, Azagra S,
JSGriskevicius A,
Puchhammer-Stöckl
A, Stanekova D, Stanojevic M, Van
Gerich T, Lens V, Seil E,
R, Sönnerborg
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N,van
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L, WeberA,J,Albert
Lens VJ, Hamouda O,
Maazoun Y,Z,Wagner
Frambach P.
Grossman
HorbanDR,
A, Kolupajeva
T, Korn K, Kostrikis L, Linka KL,
Hana A, Berthold
C, Gunness
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JBR-BTR. 2014 Sep-Oct;97(5):319-20
JBR-BTR. 2014 Nov-Dec;97(6):331-5
2014;(1):7-14.
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2014;(1):7-14
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Asthma and smoking:
mix comparison between the Maine
Cardiovascular
health:aadangerous
cross-national
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DaveyHamdan
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Identification
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a Fel d 1-like molecule
a major rabbit
Autophagic
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GZMB/granzyme
B: a newasmechanism
of
allergen tumor cell escape from natural killer cell-mediated lysis
hypoxic
Hilger
Kler S, Arumugam
Muller
CP, Charpentier
C,Janji B.
Viry
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Baginska
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Les facteurs an
deadaptive
risque d'allergie
alimentaire
l'adulte.
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metabolic
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to stress
shaping the
antitumor immunity
Morisset
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Hilger C, Lehners
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J, Baginska J,F,Mgrditchian
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Biochem
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Berchem
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Pneumologie
Bronchial airway
gene expression
smokers
with
lung or head
and neck
BAG6/BAT3
modulates
autophagyinby
affecting
EP300/p300
intracellular
cancer
localization.
Van Dyck
E, Nazarov
PV, Muller A,
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S, Prébois
C, Pérez-Gracia
E, Nicot
BauvyN,C,Bosseler
DesmotsM,F,Pierson
Pirot N,S,
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V, Mascaux
C, KnolleV,U,Berchem
Ninane V,
R, Bremnes
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C,
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AV, Palissot
G,Nati
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P, Linares
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M. S
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E, Pattingre
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Médecine du
HématologieSport
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of previous
injury and speed
with running
style
and stride-toBAT3
modulates
p300-dependent
acetylation
of p53 and
autophagystride fluctuations
related
protein 7 (ATG7) during autophagy
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Médecine du
Sport
Orthopédie
Berchem
Guy
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Berchem
Dietrich
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Moderate to severe injuries in football: a one-year prospective study of
twenty-four
female
andexpression
male amateur
teams. with lung or head and neck
Bronchial
airway
gene
in smokers
cancer
2D and 3D MOCART scoring systems assessed by 9.4 T high-field MRI
correlate with elementary and complex histological scoring systems in a
translational
of osteochondral
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ofmodel
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by the histone
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First-line
crizotinib versus chemotherapy in ALK-positive lung cancer.
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K, Theisen
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Lion A, Theisen D, Windal T, Malisoux L, Nührenbörger C, Huberty R,
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GoebelL,L,Berchem
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Berchem
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complications.
Pape
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Dietrich
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2014;(1):7-14
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Surname
Pape
Name
Dietrich
Service
Orthopédie
Authors
Gerich
T, Bogdan A, Backes F, Gillman T, Seil R, Pape D
Publication
Bull
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2014;(1):7-14
Balotta
Beshkov
Pape
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Pape
HC. D, Camacho RJ, Clotet B, Coughlan S, Griskevicius A,
Puchhammer-Stöckl
E, Sönnerborg
A,Seil
Stanekova
Stanojevic M, Van
Pape
D, van Heerwaarden
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R, MadryD,H.
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Abecasis A,M.
Albert J, Hamouda O,
Madry
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Teeter
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Giffin
JR.
Grossman
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Linka
KL,
Lorbach
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Boucher O,
C, Pape
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fixator.
Pape
Arendt
Dietrich
Victor
Orthopédie
Maladies
Infectieuses
complications.
Pape
Dietrich
Orthopédie
Osteoporotic periprosthetic fractures and fractures close to joints in the
elderly: an interdisciplinary challenge.
Pape
Dietrich
Orthopédie
Osteotomy techniques close to the knee. Effect on wedge volume and bony
contact surface.
Arendt
Pape
Victor
Dietrich
Maladies
Orthopédie
Infectieuses
Patterns ofchanges
transmitted
HIV
drugtibiofemora
resistance in
Europe vary after
by risk
group
Structural
in the
lateral
compartment
high
tibial
osteotomy
Pape
Dietrich
Orthopédie
Radiostereometric analysis of early anatomical changes following medial
opening wedge high tibial osteotomy. Knee
Pape
Dietrich
Orthopédie
Medial unicondylar knee replacement
Arendt
Pape
Victor
Dietrich
Maladies
Orthopédie
Infectieuses
Azagra
Juan S.
Pape
Bache
Dietrich
Manon
Chirurgie
générale
Orthopédie
Néonatologie
Backes
Pape
François
Dietrich
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Backes
Dietrich
François
Orthopédie
Traumatologie
Philippe
Paul
Beissel
Philippe
Jean
Paul
Berchem
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Guy
Paul
Berchem
Pillet
Berchem
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Jean
Christophe
Guy
Pizon
Emmanuelle
Berchem
Plawny
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Evaluation et
Rééducation
Cancérologie
Effect
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high tibialpatient
osteotomy on the lateral tibiofemoral
treatment-naïve
HIV-2-infected
compartment in sheep. Part II: standard and overcorrection do not cause
articular
Minimallycartilage
invasive degeneration.
management of postoperative esophagojejunal
anastomotic leak
Effect of open wedge high tibial osteotomy on the lateral tibiofemoral
compartment
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Partstimulation
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oforal
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microstructure
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subchondral
bone and
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trial.
meniscus.
Sense
or nonsense
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braces to the supra-acetabular external
the anterior
pelvic ring.
An alternative
fixator.
Small subchondral drill holes improve marrow stimulation of articular
cartilage
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plate osteosynthesis for osteoporotic fractures of
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fixator.
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de l’œsophage
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Study
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l’œsophage
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sigmoidienne
parcell-mediated
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hypoxic
tumor
cell escape from
natural killer
patientes, quand et comment?
Comparative
Doppler flow measurements of the ulnar artery and of the
antitumor immunity
detect
steal syndromes
BAG6/BAT3
modulates autophagy by affecting EP300/p300 intracellular
localization.
BAT3 modulates p300-dependent acetylation of p53 and autophagyDisruption
of autophagy
the histone
deacetylase inhibitor MGCD0103
related protein
7 (ATG7) by
during
autophagy
Plawny
Berchem
Laurent
Guy
Cancérologie
Emerging
new anticancer
biological
in 2013
Bronchial airway
gene expression
in therapies
smokers with
lung(haematological
or head and neck
malignancies).
cancer
Plawny
Laurent
Berchem
Guy
Hématologie-
three
exceptional
cases by the histone deacetylase inhibitor MGCD0103
Disruption
of autophagy
Poulain
Virginie
Berchem
Guy
Prospert
Fernand
Prospert
Berchem
Fernand
Guy
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Comparative
Doppler flow
measurements
ulnar artery
and of the
randomized
trialsof
in the
European
and Chinese
postanastomotic
radial artery
in cancer:
radiocephalic
arteriovenous
fistulas to
patients with nonsmall-cell
lung
the BRCA1-RAP80
Expression
detect
steal syndromes
Customization
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Pull
Charles
Psychiatrie
Personality disorders in Diagnostic and Statistical Manual of Mental
Disorders-5: back to the past or back to the future?
Pull
Charles
Psychiatrie
The downward spiral of mental disorders and educational attainment: a
systematic review on early school leaving
Bernard
Ries
Florian
Fernand
Neurochirurgie
Improvingnew
the Consistency
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Deep Brain
Structure
Segmentations
Emerging
anticancer biological
in 2013
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malignancies).
Cancérologie
Chirurgie
générale
Néphrologie
anastomotic
leak versus chemotherapy in ALK-positive lung cancer.
First-line crizotinib
0,66
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Ziegler R, Goebel L, Seidel R, Cucchiarini M, Pape D, Madry H
Orthopade. 2014 Oct;43(10):875-6,
878-82
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2014;22(7):1666-77
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Dev.
2014
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Orthopäde.
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Eldracher M, Orth P, Cucchiarini M, Pape D, Madry H
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AV, PalissotE,V,Brons
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Wilde
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Van Dyck
Nazarov
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Verbeeck N, Cavez N, Plawny L, Weber J, Lens V
Curr
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Gomes-Ferreira C, Schneider A, Philippe P, Lacreuse I, Becmeur F
Schneider
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Dabadie A, Faure C, Philippe P et al.
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Biomed
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JBR-BTR. 2014 Sep-Oct;97(5):319-20.
Surname
Prospert
Name
Fernand
Service
Néphrologie
Title
Comparative
Doppler flow measurements of the ulnar artery and of the
Authors
Verbeeck
N, Pillet JC, Mocanu I, Mathieu X, Prospert F
Publication
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JBR-BTR.
2014 Nov-Dec;97(6):331-5
Pull CB
Balotta
C, Beshkov
D, Camacho
RJ, Clotet
B, Coughlan
A,
Esch
P, Bocquet
V, Pull
C, Couffignal
S, Lehnert
T, GraasS,M,Griskevicius
FondGrossmanL,Z,Ansseau
Horban M
A, Kolupajeva T, Korn K, Kostrikis LG, Liitsola K,
Harmant
Puchhammer-Stöckl
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Ergometric performance and cardiovascular profile of obesity clinic
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for osteoporotic
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of midsole hardness
of standard cushioned
shoes onfractures
running-of
the
anterior
related
injurypelvic
risk ring. An alternative to the supra-acetabular external
fixator.
Injuries in youth sports – epidemiology, risk factors and prevention
fixator.
twenty-four female and male amateur teams.
Physical activity
promotion
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in patients
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ORISCAV-LUX
(Luxembourg).
communicable diseases: the situation in the Grand-Duchy of Luxembourg.
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Radiologie
Comparative Doppler flow measurements of the ulnar artery and of the
postanastomotic
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BAT3
modulates p300-dependent
acetylation of
p53 and autophagydetect steal
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related
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Berchem
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Guy
Wagner
Daniel
Radiologie
Cardiologie
Berchem
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Guy
Daniel
Cancérologie
three exceptional
casesexpression in smokers with lung or head and neck
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airway gene
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thrombospondin-1 by macrophages
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of adenosine
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and
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implication
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Daniel
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treated HIV disease
Urhausen A, Seil R.
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G, Schlesser
M. B, Devaux Y, Wagner DR
2014;(3):7-24
Sportorthop Sporttraumatol 2014; 30 :
31-42
366-370
Autophagy. 2014 Jul;10(7):1341-2.
JBR-BTR. 2014 Sep-Oct;97(5):319-20
JBR-BTR. 2014 Nov-Dec;97(6):331-5
18;111(11):4115-20
2,32
11,42
2,29
4,65
11,42
9,80
JBR-BTR. 2014 Mar-Apr;97(2):76-80
Cancer Med. 2014 Apr;3(2):322-36
J Leukoc Biol. 2015 Jan;97(1):9-18
4,30
Leukemia. 2014 Aug;28(8):1636-46
PLoS One. 2014 Mar 20;9(3):e92715
9,37
3,53
Identification of Candidate Long Noncoding RNAs Associated with Left
Ventricular Hypertrophy
LenoirS,
B,Plawny
WagnerL,DR,
Sala-Newby
Wilde
VanBlacher
Dyck E,S,Berchem
G GB, Newby AC, Noel A,
Devaux Y
Zhang L, Hamad
EA,J,Vausort
Funakoshi
H, Feldman
Cappuzzo
F, Paolini
Usari T,M,
Iyer
S, Reisman
A, WilnerAM,
KD, Wagner
Tursi J, DR,
Devaux Y.F; PROFILE 1014 Investigators.
Blackhall
N Engl J Med. 2014 Dec 4;371(23):2167-77
Clin Transl Sci. 2014 Nov 10
54,42
2,11
Identification
of candidate
long non-coding
in response
to
Two
biomarker-directed
randomized
trials inRNAs
European
and Chinese
myocardial
infarction
patients
with
nonsmall-cell lung cancer: the BRCA1-RAP80 Expression
Long noncoding RNAs in patients with acute myocardial infarction
Zangrando
J, Zhang
L, Vausort
PY,Bover
Wagner
DR, L,
in
Moran T, Wei
J, Cobo
M, QianM,
X, Maskali
DomineF,M,Marie
Zou Z,
I, Wang
Devaux Y M, Yu L, Chaib I, You C, Massuti B, Song Y, Vergnenegre A, Lu
Provencio
Vausort
M, Wagner
DR,
Y
Chen
X, de
Las Peñas
R,Devaux
Karachaliou
N, Sala MA, Wu Q, Isla D, Zhou Y,
BMCOncol.
Genomics.
Jun 10;15:460
Ann
20142014
Nov;25(11):2147-55
4,04
6,57
Circ Res. 2014 Sep 12;115(7):668-77
11,08
Wagner
Daniel
Cardiologie
Wagner
Daniel
Cardiologie
Bernard
Florian
Neurochirurgie
Wagner
Daniel
Cardiologie
Role of MicroRNAs in Endothelial Progenitor Cells: Implication for Cardiac
Repair
by
Combining
Variational
Simultaneous
Multi-Modality
Unity
is strength
- A panelInterpolation,
of 4 microRNAs
decreases cardiomyocyte
Baize N, Zhang F, Garde J, Germonpre P, Rauh S, ALHusaini H, SanchezMaazoun Y, Wagner DR, Frambach P
Centre of
Tower
HospitalYin Nanjing
Goretti
E, Drum
Wagner
DR, Devaux
Goretti E, Zangrando J, Wagner DR, Devaux Y.
2014;(1):45-56
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Walter
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Boston.
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Int J Cardiol.
2014 Dec
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Wagner
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Cardiologie
Effects of adenosine on lymphangiogenesis
Lenoir B, Wagner DR, Blacher S, Sala-Newby GB, Newby AC, Noel A,
Devaux Y
PLoS One. 2014 Mar 20;9(3):e92715
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Wagner
Daniel
publications
Cardiologie
Identification of Candidate Long Noncoding RNAs Associated with Left
Ventricular Hypertrophy
Zhang L, Hamad EA, Vausort M, Funakoshi H, Feldman AM, Wagner DR,
Devaux Y.
Clin Transl Sci. 2014 Nov 10
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Wagner
Surname
Name
Daniel
Service
Cardiologie
Title
myocardial infarction
Identification of candidate long non-coding RNAs in response to
Zangrando J, Zhang L, Vausort M, Maskali F, Marie PY, Wagner DR,
Authors
Devaux
Y
Impact
4,04
Factor
2014
Wagner
Abou Hamdan
Daniel
Kamal
Cardiologie
Pneumologie
Long noncoding RNAs in patients with acute myocardial infarction
Vausort M, Wagner DR, Devaux Y
Circ Res. 2014 Sep 12;115(7):668-77
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Wagner
Arendt
Daniel
Victor
Cardiologie
Maladies
Infectieuses
2014;(1):45-56
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Wagner
Daniel
Cardiologie
Role of MicroRNAs in Endothelial Progenitor Cells: Implication for Cardiac
Repair
Wagner
Daniel
Cardiologie
Unity is strength - A panel of 4 microRNAs decreases cardiomyocyte
hypertrophy
Maazoun Y, Wagner DR, Frambach P
Balotta
C, Wagner
BeshkovDR,
D, Camacho
Goretti E,
Devaux YRJ, Clotet B, Coughlan S, Griskevicius A,
Puchhammer-Stöckl
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Goretti E, ZangrandoE,
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Victor
Nadège
Maladies
Dermatologie
Infectieuses
Patterns
of transmitted
HIV drug
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in Europe
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risk agroup
Dermatological
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Gil
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Virological
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2014 Sep 24;28(15):2329-31
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Maladies
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Anesthésie
Chirurgie
générale
Pneumologie
Néonatologie
in
Frentz D, van
Vijver D, Abecasis
A, Albert
Hamouda
O,
Bernardeschi
C, de
Valeyrie-Allanore
L, Ortonne
N,J,
Gressier
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Jørgensen
Kücherer
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Asjö
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PH,
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Duclos-Vallée
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Samuel
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PolB,
S,
Balotta
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BerginN.
C, Beshkov D, Camacho R, Clotet B, Griskevicius A,
Milpied B,
Verbeeck
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Weber
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V
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C, N,
Otelea
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Paraskevis
Paredes
R, Poljak
M, PuchhammerStöckl E, Sönnerborg A, Stanekova D, Stanojevic M, Vandamme AM,
Hilger C, Kler S, Arumugam K, Revets D, Muller CP, Charpentier C,
LehnersY,C,
Morisset
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Zheng
Lambert
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Arendt
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François
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Guy
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Berchem
Guy
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31-42
4,65
Berchem
Guy
localization.
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11,42
Berchem
Guy
18;111(11):4115-20
9,80
Berchem
Guy
cancer
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Berchem
Guy
Leukemia. 2014 Aug;28(8):1636-46
9,37
Berchem
Guy
N Engl J Med. 2014 Dec 4;371(23):2167-77
54,42
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Ann Oncol. 2014 Nov;25(11):2147-55
6,57
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78
Bernard
Florian
Neurochirurgie
Charpentier-Chaix C, Abou Hamdan A, Wirtz G, Morisset M, Schlesser M
BMC Genomics. 2014 Jun 10;15:460
J Stem Cells. 2014;9(2):107-15
JBR-BTR. 2014 Mar-Apr;97(2):76-80
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79
1,23
ACADEMIC TITLES
ACADEMIC TITLES - TRAINER STATUS
Name
Name
Last name
Last name
Speciality
Speciality
Atlan
Catherine
Endocrinology
Atlan
Catherine
Endocrinology
Azagra
Santiago
Surgery
Azagra
Santiago
Surgery
Academic
Achievement
Academic
Achievement
PhD Nutrition, Mediteranean
University
, Aix-Marseille,
PhD
Nutrition,
Mediteranean
1999
University
, Aix-Marseille,
1999
Guillaume
Policinical
Guillaume
Guy
Berchem
Guy
Policinical
Hemato oncologyHemato
PhD, University Paris Sud
(XI), University
2014
PhD,
Paris Sud
(XI), 2014
PhD, Karolinska Institute
Stockholm,
2010Institute
PhD,
Karolinska
Stockholm,
2010
Priv.-Doz. University
Bonn,
venia legendi
Neurologie
Priv.-Doz.
University
Bonn,
University
Bonn
2001
venia
legendi
Neurologie
Berglund
Sophie
Gynecology
Berglund
Beyenburg
Sophie
Stefan
Gynecology
Neurology
Beyenburg
Stefan
Neurology
Bindl
Lutz
Pediatrics
Bindl
Lutz
Pediatrics
Biver
Armand
Pediatrics
Biver
Armand
Pediatrics
BoecherSchwarz
BoecherSchwarz
Hans
Neurosurgery
Hans
Neurosurgery
Bottu
Jean
Bottu
Jean
Calteux
Nicolas
Pediatrics neonatology
Pediatrics
neonatology
Plastic surgery
Calteux
Nicolas
Plastic surgery
Dadoun
Frédéric
Endocrinology
Dadoun
Frédéric
Endocrinology
de Beaufort
Carine
de Beaufort
Carine
Pediatric
endocrinology
Pediatric
endocrinology
De Bruyne
Filip
Gynecology
De Bruyne
Diederich
Filip
Nico
Gynecology
Neurology
Diederich
Nico
Neurology
Dooms
Georges
Medical Imaging
Dooms
Georges
Medical Imaging
Official trainer of
german trainer
Chamber
Official
of of
Physicians
german
Chamber of
(Ärztekammer)
Physicians
(Ärztekammer)
Official trainer
of medical
Official
trainer
student
in
of
medical
Germanyinyears
student
1 to 5
Germany
years
1 to 5
Official
trainer of
Official
medicalof
trainer
student 6th
medical
year
student
6th
year
Official trainer
of medical
Official
trainer
student
from
of
medical
Belgiumfrom
student
Belgium
Official
trainer from
Official
Health from
trainer
Ministry
Health
Belgium
Ministry
Belgium
Academic
positions
Academic
positions
Research
position
Research
position
Lecturer University of
Mediterranée,
Aix- of
Lecturer
University
Marseille,2000AixMediterranée,
Marseille,2000
Lecturer, University of
Granada University of
Lecturer,
Honorary professor and
Granada
lecturer, the
mini- and
Honorary
professor
Invasive Surgical
lecturer,
the mini-Institut
of Caceres
(J.Uson)
Invasive
Surgical
Institut
of Caceres (J.Uson)
Bauer
Bauer
Berchem
oncology
Official
trainer
Official
from the
trainer
University
from
the of
Luxembourg
University
of
Luxembourg
University
Bonn 2001Bonn,
venia legendi
University
Priv.-Doz.
University
Bonn,
Bonn, legendi
2005 University
venia
Bonn,
2005 and
DIU medicine
adolescent
health
DIU
medicine
and (june
2015)
adolescent
health (june
Luxembourg
Institute of Health
Luxembourg
(LIH), head
of the
Institute
of Health
Laboratory
(LIH),
head of
of the
Experimental
Laboratory
of
Hemato-Oncology
Experimental
Hemato-Oncology
Saarland Chamber of
Physicians
(Neurology
Saarland
Chamber
of 6 years) (Neurology Physicians
University Bonn
University Bonn
6
years) Chamber of
Saarland
Physicians
(Pediatrics
Saarland
Chamber
of 1 year)
Physicians
(Pediatrics 1 year)
Requested from
Saarland from
Requested
University
Saarland
University
2015)
Priv.-Doz. et Venia legendi,
University etMainz,
Priv.-Doz.
Venia2001,
legendi,
dozent der Mainz,
University
University
2001,Wien,
2003 der University Wien,
dozent
2003
Catholic University
Louvain University
Catholic
University Liège
Louvain
University
Liège
Catholic University
Louvain University
Catholic
Louvain
PhD, University Marseille,
1999 University Marseille,
PhD,
1999
PhD, University Rotterdam,
1986 University Rotterdam,
PhD,
Marseille
Guest professor at VUB
Brussels
Guest
professor at VUB
1986
Habilitation Neurology; venia
legendi,
University
Kölnvenia
Habilitation
Neurology;
legendi, University Köln
80
Priv.-Doz. University Geneva,
1994
1994
Lecturer and trainer at
French College
of at
Lecturer
and trainer
Plastic Surgery
French
College of
Plastic
Surgery
Lecturer
University of
Mediterranée,
Aix- of
Lecturer
University
Marseille
Mediterranée,
Aix-
Brussels
Saarland Chamber of
Physicians
(Neurology
Saarland Chamber
of 6
years) (Neurology Physicians
6 years)
University Köln
University Köln
Saarland
University
Saarland
University
Catholic University
Louvain
Catholic University
Louvain
Academic consultant
KUL 03/2014
Academic
consultant
KUL
03/2014
Invited
Professor, Koln
University
Invited Professor, Koln
Visiting
Assistant
University
Professor
Rush
Visiting Assistant
University Rush
Med. Center,
Professor
Chicago
University Med. Center,
Chicago
Lecturer at the
University
Geneva,
Lecturer atof
the
pre-and
post
graduate,
University
of Geneva,
ResearchER at the
Luxembourgat the
ResearchER
Center for System
Luxembourg
in Biomedicin
Center
for System
(LCSB)
in
Biomedicin
(LCSB)
Research at the
Luxembourg
Research at the
Center
for System
Luxembourg
in
Biomedicin
Center
for System
(LCSB)
in Biomedicin
(LCSB)
81
Calteux
Nicolas
Plastic surgery
Endocrinology
Dadoun
Frédéric
academic
titles
de Beaufort
Carine
Name
Last name
Pediatric
endocrinology
Speciality
Catholic University
Louvain
1999
1986
Academic
Achievement
Official
trainer
from the
University of
Luxembourg
Official trainer of
german Chamber of
Physicians
(Ärztekammer)
De Bruyne
Filip
Gynecology
Atlan
Catherine
Endocrinology
Diederich
Nico
Neurology
Azagra
Santiago
Surgery
Dooms
Georges
Medical Imaging
Bauer
Guillaume
Policinical
Berchem
Droste
Guy
Dirk
Hemato Neurology
oncology
20002014
Habilitation
(XI),
Neurologie; venia legendi
University Münster
Erpelding
Berglund
Jeff R.
Sophie
Cardiology
Gynecology
Even
Annette
Policlinical
Stockholm, 2010
Beyenburg
Fogen
Stefan
Frédéric
Neurology
Palliative care
Priv.-Doz. University Bonn,
venia legendi Neurologie
University Bonn 2001
Saarland
Saarland Chamber
Chamber of
of
Physicians
Physicians (Neurology
(palliativ
6
years) - 12 months)
medicine
Bindl
Forges
Lutz
Thierry
Pediatrics
Assisted
reproduction
Gerich
Biver
Torsten
Armand
Traumatology
Pediatrics
Priv.-Doz.
University
Bonn,
PhD, University
Nancy,
venia
2004 legendi University
Bonn, 2005
Saarland Chamber of
Physicians (Pediatrics 1 year)
Goergen
BoecherSchwarz
Hermand
Martine
Hans
Surgery
Neurosurgery
Jean-Paul
Gynecology
Bottu
Jean
Hertel
Frank
Neurosurgery
Calteux
Kieffer
Nicolas
Isabelle
Plastic surgery
Pediatrics
University
, Aix-Marseille,
Habilitation
Neurology; venia
1999
Official trainer
of medical
student in
Germany years
1 to 5
Official
trainer of
medical
student 6th
year
Official trainer
of medical
student from
Belgium
Saarland
University
Saarland Chamber of
Physicians (Neurology 6 years)
University Köln
Catholic University
Louvain
Saarland Chamber of
Saarland
University
positions
Academic consultant
KUL 03/2014
Lecturer
University of
Mediterranée,
Aix-Koln
Invited Professor,
Marseille,2000
University
Visiting Assistant
Lecturer,
University of
Professor Rush
Granada
Universityprofessor
Med. Center,
Honorary
and
Chicago the minilecturer,
ResearchER at the
Luxembourg
Research
Center for System
position
in Biomedicin
(LCSB)
Research at the
Luxembourg
Center for System
in Biomedicin
(LCSB)
Invited professor,
University Münster
Seminar teacher of the
German Society of
Ultrasound in medicine
Luxembourg
Institute of Health
(LIH), head of the
Laboratory of
Experimental
Hemato-Oncology
University Bonn
University Hannover
Requested from
Saarland
University
Invited professor,
emergency medicine,
Hochschule Hannover
Saarland
University
University Mainz, 2001,
dozent der University Wien,
2003
Saarland Chamber of Physicians (Neurosurgery-6 years)
Catholic University
Louvain
University Liège
University Mainz
Catholic University
Louvain
Krueger
Rejko
Neurology
Frédéric
Endocrinology
legendi
der University
PhD,
University
Marseille,
Tübingen
1999
de Beaufort
Carine
Pediatric
endocrinology
1986
De Bruyne
Filip
Gynecology
Le Saint
Diederich
Laurent
Nico
Psychiatry
Neurology
Saarland Chamber of
University Köln
Max
Martin
Neurosurgery
Georges
Medical Imaging
Saarland Chamber of Physicians (Anesthesia - 5 years)
specialised in anesthesiology
- intensive medicine
Saarland University
Dooms
Metz
René
Neurology
priv. Doz and venia legendi
in internsive care medicine
and anesthesiology,
UniversityUniversity
of Homburg,
Priv.-Doz.
Geneva,
1994
Morisset
Droste
Martine
Dirk
ImmunoNeurology
allergology
Mühe
Annette
Psychiatry
Nati
Erpelding
Romain
Jeff
R.
Pulmonology
Cardiology
Saarland
University
PhD, University Nancy, 2008
2000 Habilitation
University Münster
Brussels
Academic
pre-and post graduate,
1994
DIU medicine and
adolescent health (june
2015)
Habilitation University
Mainz
Official
trainer from
Health
Ministry
Belgium
Mediterranée, AixMarseille
Invasive
LecturerSurgical
at the Institut
of
Caceres of
(J.Uson)
University
Geneva,
1994
Dadoun
82
French College of
Plastic Surgery
Catholic University
Louvain
Saarland Chamber of Physicians (Neurology - 6 years)
Saarland Chamber of
Saarland Chamber of Physicians (Psychiatrie 2 years)
Rheinland Pfalz Chamber of
Saarland
University
Saarland
University
Catholic University
Louvain
Lecturer at the Catholic
University of Louvain
and at the Free
University of Brussels
French College of
Plastic
Surgery
Professor
at the
University
of
Lecturer University
of
Luxembourg AixMediterranée,
Associate
Professor
and
Marseille
Head of the Laboratory
Guest
professor at VUB
for Functional
Brussels
Neurogenomics HertieInstitute for Clinical
Brain Research and
German Center for
Neurodegenerative
Academic
consultant
Diseases,
Tübingen
KUL
03/2014
Lecturer
in clinicalKoln
Invited
Professor,
sexology, University of
University
Metz-Nancy
Visiting
Assistant
Professor Rush
Chicago
Lecturer at the
University of Geneva,
1994
Lecturer at the
Invited
professor,
University
of MetzUniversity
Münster
Nancy
German Society of
PEARL Chair and
Head of Clinical
and Experimental
Neuroscience unit,
at the Luxembourg
ResearchER
at the
Center for System
Luxembourg
Biomedicin
Center for System
in Biomedicin
(LCSB)
Research at the
Luxembourg
Center for System
in Biomedicin
(LCSB)
83
Brain Research and
German Center for
Neurodegenerative
Diseases, Tübingen
academic titles
Le Saint
Psychiatry
priv.
Doz and venia legendi
Academic
in
internsive care medicine
Achievement
and anesthesiology,
University of Homburg,
Official
trainer
from the
University of
Luxembourg
Official trainer of
Saarland
of PhysigermanChamber
Chamber
of
cians
(Anesthesia - 5 years)
Physicians
specialised in anesthesiology
(Ärztekammer)
- intensive medicine
Max
Martin
Neurosurgery
Metz
Atlan
René
Catherine
Neurology
Endocrinology
Morisset
Martine
Azagra
Santiago
Immunoallergology
Surgery
Mühe
Annette
Psychiatry
Saarland Chamber of Physicians (Psychiatrie 2 years)
Nati
Romain
Pulmonology
Bauer
Panosetti
Berchem
Guillaume
Eugène
Guy
Policinical
ORL
Hemato oncology
Physicians (Pulmonology 2 years)
Pape
Dietrich
Orthopedy
Berglund
Sophie
Gynecology
Beyenburg
Stefan
Neurology
Pauly
Bindl
Fernand
Lutz
Reeducation
Pediatrics
Petit
Michel
Policlinical
Philippe
Biver
Paul
Armand
Pediatrics Pediatrics
surgery
BoecherSchwarz
Hans
Neurosurgery
Bottu
Pouthier
Jean
Dominique
Pediatrics Nephrology
neonatology
Ries
Calteux
Fernand
Nicolas
Hemato oncology
Plastic
surgery
Sanchez
Ana
Policlinical
Schlesser
Dadoun
Marc
Frédéric
Pulmonology
Endocrinology
Schmit
de Beaufort
Jean-Claude
Carine
ImmunoPediatric
allergology
endocrinology
PhD KUL, 1998
1986
Schmitz
Bernd
Anesthesia
De Bruyne
Seil
Filip
Romain
Gynecology
Orthopedy
Priv.-Doz. venia legendi
University ErlangenNürnberg, 2001
Saarland Chamber of
Physicians (Anesthesia 5 years)
Diederich
Nico
Neurology
Saarland Chamber of
Physicians (specialised Sport
Saarland
medicine)Chamber of
Simon
Marc
Policlinical
Dooms
Stammet
Georges
Pascal
Medical Imaging
Reanimation
Name
84
Laurent
Last name
Speciality
Staub
Thérèse
Droste
Urhausen
Dirk
Axel
Infectious
diseases
Neurology
Sport medicine
Erpelding
Jeff R.
Cardiology
University
, Aix-Marseille,
PhD, University
Nancy, 2008
1999
Official trainer
of medical
Saarland University
student in
Germany years
1 to 5
Official
trainer of
medical
student 6th
year
Official trainer
of medical
student from
Belgium
Saarland Chamber of Physicians (Neurology - 6 years)
Official
trainer from
Health
Ministry
Belgium
Lecturer in clinical
sexology, University of
Metz-Nancy
Academic
positions
Mediterranée,
Lecturer at theAixMarseille,2000
University of MetzSaarland
University
Catholic University
Louvain
Nancy University of
Lecturer,
Granada
lecturer, the miniInvasive Surgical Institut
of Caceres (J.Uson)
Lecturer at the
University of Berne (CH)
Invited Professor at the
University of Liège
(XI), 2014
Saarland, 2013
Stockholm, 2010
venia legendi Neurologie
Saarland Chamber of
venia legendi University
Bonn, 2005
Saarland Chamber of
Physicians (Pediatrics 1 year)
University Bonn
2003
Catholic University
Louvain
University
Liège
Catholic University
Louvain University
Catholic
Louvain
Physicians (Pulmonology 2 years)
French College of
Plastic Surgery
Brussels
Saarland
University
University Köln
Saarland
Saarland
University
University
Catholic University
Louvain
Catholic University
Louvain
PhD Student, University
1994
Liège
2000 Habilitation
Neurologie;
venia legendi
Priv.-Doz. Saarland
University
Münster
University, 1994,
Lecturer at the
University of Bologna in
pediatric minimally
invasive surgery.
Instructor at the IRCAD
EITS centre in
Strasbourg and the
IRCAD America centre
in Barretos (Brasil)
Saarland University
Saarland Chamber of
Physicians
(Neurology
Saarland Chamber
of 6
years)
Physicians
(specialised sport
medicine)
University des
Saarland
University Potsdam
Saarland
University
Luxembourg
Institute of Health
(LIH), head of the
Laboratory of
Experimental
Luxembourg
Hemato-Oncology
Institute of Health
(LIH), associated
head of the Sport
Medecine Research
Laboratory.
Lecturer, University of
Strasbourg
Requested from
Saarland
University
DIU medicine and
2015)
1999
Research
position
Academic consultant
Invited
professor,
KUL
03/2014
Saarland University
University
Visiting Assistant
Professor Rush
Chicago
Luxembourg
ResearchER
at the
Institute of Health
Luxembourg
(LIH), director
Center for System
in Biomedicin
(LCSB)
Luxembourg
Institute of Health
Research
at the
(LIH), associated
Luxembourg
head of the Sport
Center
for Research
System
Medecine
in
Biomedicin
Laboratory.
(LCSB)
Lecturer at the
1994
Invited professor,
University
Münster
Invited professor,
Seminar
of the
Saarlandteacher
University
German Society of
Luxembourg
Institute of Health
(LIH), associated
head of the Sport
Medecine Research
85
Schmitz
Bernd
Anesthesia
Orthopedy
Priv.-Doz. venia legendi
University ErlangenNürnberg, 2001
Saarland Chamber of
Physicians (Anesthesia 5 years)
Seil
Romain
academic
titles
Name
Last name
Speciality
Simon
Marc
Policlinical
Stammet
Atlan
Pascal
Catherine
Reanimation
Endocrinology
Staub
Thérèse
Azagra
Urhausen
Santiago
Axel
Infectious
diseases
Surgery
Sport medicine
Bauer
Van Wymersch Guillaume
Didier
Berchem
Guy
Academic
Achievement
Official
trainer
from the
University of
Luxembourg
Saarland Chamber of
Physicians (specialised Sport
medicine)
Official trainer of
german Chamber of
Physicians
(Ärztekammer)
Saarland
University
Saarland University
Saarland
University
Official trainer
of medical
student in
Germany years
1 to 5
Official
trainer of
medical
student 6th
year
Invited professor,
Saarland University
Official trainer
of medical
student from
Catholic University
Belgium
Louvain
PhD Student, University
LiègeNutrition, Mediteranean
PhD
University , Aix-Marseille,
1999
Priv.-Doz. Saarland
University, 1994,
Official
trainer from
Health
Ministry
Belgium
Academic
positions
Saarland Chamber of
Physicians (specialised sport
medicine)
Lecturer,
University of
Invited professor,
Granada
Saarland University
lecturer, the miniInvasive Surgical Institut
of Caceres (J.Uson)
University des
Saarland
University Potsdam
Vervier
Jean-François
Wagner
Daniel
Cardiology
PhD University Catholic
Louvain, 1999
Berglund
Sophie
Gynecology
Stockholm, 2010
Beyenburg
Stefan
Neurology
Weber
Joseph
Gastroenterology venia legendi Neurologie
Bindl
Lutz
Pediatrics
Witsch
Michael
Biver
Armand
Pediatric
endocrinology
Pediatrics
BoecherSchwarz
Hans
Neurosurgery
Bottu
Jean
Catholic University
Louvain
University Liège
Calteux
Nicolas
Plastic surgery
Catholic University
Louvain
Dadoun
Frédéric
Endocrinology
1999
de Beaufort
Carine
Pediatric
endocrinology
1986
Brussels
De Bruyne
Filip
Gynecology
Diederich
Nico
Neurology
Dooms
Georges
Medical Imaging
1994
Droste
Dirk
Neurology
2000 Habilitation
University Münster
86
Erpelding
Jeff R.
Cardiology
Catholic University
Louvain
(XI), 2014
DIU medicine and
2015)
position
Mediterranée, AixMarseille,2000
Policinical
Gynecology
Hemato oncology
Pedopsychiatry
venia legendi University
Bonn, 2005
Luxembourg
Institute of Health
(LIH), associated
head of the Sport
Medecine Research
Research
Laboratory.
Lecturer at University
Paris XIII
Saarland Chamber of
Physicians
(Neurology
Saarland Chamber
of 6
years)
Physicians
University Bonn
Luxembourg
Institute of Health
(LIH), associated
head of the Sport
Medecine Research
Laboratory.
Luxembourg
Institute of Health
(LIH), head of the
Laboratory of
Luxembourg
Experimental
Institute of Health
Hemato-Oncology
(LIH), head of the
Laboratory of
Cardiovascular
Research
Saarland
University
Requested from
Saarland
University
(Gastroenterology
- 3 years)
Saarland
Chamber of
Physicians
(Pediatrics Baden-Württemberg
1Chamber
year)
of Physicians
(specialised pediatric
endocrinology)
2003
Saarland
University
Saarland Chamber of
University Köln
French College of
Plastic Surgery
ResearchER at the
Luxembourg
Center for System
in Biomedicin
(LCSB)
Academic consultant
KUL 03/2014
Catholic University
Louvain
University
Visiting Assistant
Professor Rush
Chicago
Research at the
Luxembourg
Center for System
in Biomedicin
(LCSB)
Lecturer at the
1994
Saarland Chamber of
Saarland
University
Invited professor,
University Münster
German Society of
87
chapters in books
Surname
Surname
88
Name
Name
Service
Service
Chapter
Chapter
Authors
Authors
Book title
Book title
Editor
Editor
Azagra
Juan
Surgery
Laparoscopic liver surgery
Juan
Surgery
Ramia JM, de la Plaza R, Adel F,
Goergen
Garcia-Parreno
J, Azagra
Ramia JM,M,de
la Plaza R, Adel
F,
JS
Goergen
M, Garcia-Parreno J, Azagra
Laparoscopy, Procedures, Pain Management and
Postoperatives
Complications
Laparoscopy, Procedures,
Pain Management and
Nova Medical N.Y.
Azagra
Neurochirurgie
Chaudhuri
KR, Tolosa E, Schapira A, Poewe W (eds). Nonmotor
symptoms
in Parkinson’s
disease.
2ndWedition
Chaudhuri
KR, Tolosa
E, Schapira
A, Poewe
(eds). Non-
Boecher-Schwarz
Hans
Neurosurgery
Zerebrale Aneurysmabehandlung
JS
Boecher-Schwarz
H, Standhard H
Boecher-Schwarz
Diederich
Hans
Nico
Neurosurgery
Neurology
Psychosis
in Parkinson’s disease
Boecher-Schwarz
H, Standhard
Goetz
CG, Diederich
NJ, FénelonHG
Diederich
Diederich
Nico
Nico
Neurology
Neurology
Goetz CG, Diederich NJ, Fénelon G
Diederich, NJ, Goetz CG, Stebbins GT
Diederich
Nico
Neurology
Psychosis in Parkinson’s disease
The pathology of hallucinations:
one
or several points
of processing
The pathology
of hallucinations:
breakdown?
one or several points of processing
Goergen
Martine
Surgery
breakdown? liver surgery
Laparoscopic
Goergen
Martine
Surgery
Diederich, NJ, Goetz CG, Stebbins GT
Hertel
Frank
Neurosurgery
Glioblastome
Ramia JM, de la Plaza R, Adel F,
Goergen
Garcia-Parreno
J, F,
Ramia
JM,M,de
la Plaza R, Adel
Azagra JSM, Garcia-Parreno J,
Goergen
Azagra
Hertel F,JS
Kortmann RD
Hertel
Hertel
Frank
Frank
Neurosurgery
Neurosurgery
Glioblastome
Lymphome des ZNS
Hertel F, Kortmann RD
Hertel F, Dornoff W
Hertel
Hoffmann
Frank
Alexander
Neurosurgery
Orthopedy
Hertel F, Dornoff W
Hoffmann A, Pape D, Dück K, Seil R
Hoffmann
Morisset
Alexander
Martine
Wachstum und
Entwicklung des Kindes
Anaphylaxis
prevention
Hoffmann A, Pape D, Dück K, Seil R
Morisset M
Morisset
Pape
Martine
Dietrich
Orthopedy
ImmunoAllergology
Immuno-
Lymphome des ZNS
Bedeutung des Sports für die Entwicklung:
Wachstum
Kindes
Bedeutung und
des Entwicklung
Sports für diedes
Entwicklung:
Anaphylaxis prevention
Radiologische Planung vor Osteotomien
Pape
Seil
Dietrich
Romain
Orthopedy
Seil
Seil
Romain
Romain
Orthopedy
Orthopedy
Radiologische
Planung vor Osteotomien
Klinische
Untersuchungstechniken
vor
Osteotomien.
Klinische Untersuchungstechniken vor
Seil
Seil
Romain
Romain
Orthopedy
Orthopedy
Seil
Romain
Orthopedy
Allergology
Orthopedy
Seil
Romain
Orthopedy
Seil
Seil
Romain
Romain
Orthopedy
Orthopedy
Seil
Seil
Romain
Romain
Orthopedy
Orthopedy
Postoperatives Complications
Neurochirurgie
motor symptoms
in Parkinson’s
Collerton
D, Mosimann
UP, Perrydisease.
E (Eds.):2nd
Theedition
Neuroscience
of Visual UP,
Hallucinations
Collerton D, Mosimann
Perry E (Eds.): The
Neuroscience of Visual Hallucinations
Laparoscopy, Procedures, Pain Management and
PostoperativesProcedures,
Complications
Laparoscopy,
Pain Management and
Postoperatives Complications
Onkologie aktuell; interdisziplinäre Empfehlungen
16.
Auflageaktuell; interdisziplinäre Empfehlungen
Onkologie
16. Auflageaktuell; interdisziplinäre Empfehlungen
Onkologie
16.
Auflageaktuell; interdisziplinäre Empfehlungen
Onkologie
16. Auflage
Sportorthopädie
und –traumatologie im Kindes- und
Jugendalter.
Sportorthopädie und –traumatologie im Kindes- und
Reference / Page
Reference / Page
Nova Medical N.Y.
Schattauer Verlag
Schattauer
Verlag Press 2014
Oxford
University
pp 184-208
Oxford University Press 2014
John Wiley & Sons, Inc., 2014
pp 184-208
pp 281-306
John Wiley & Sons, Inc., 2014
pp 281-306
Nova Medical N.Y.
Nova Medical N.Y.
Zuckschwerdt Verlag
Zuckschwerdt Verlag
Zuckschwerdt Verlag
Zuckschwerdt Verlag
Deutscher Aerzte-Verlag, 2014
pp 1-13
Jugendalter.
Ebook
"Advances in anaphylaxis management
Deutscher Aerzte-Verlag, 2014
Future medicine Ltd, London
pp 1-13
chap.8:109-123
Morisset M
Seil R, Nührenbörger C, Hoffmann A.
Ebook "Advances in anaphylaxis management
Lobenhoffer: Kniegelenknahe Osteotomien
Future medicine Ltd, London
Thieme Verlag, 2014
chap.8:109-123
Thieme Verlag, 2014
Osteotomien. after osteotomies around the Takeuchi R, Martijn M, Van
Rehabilitation
knee.
R, SeilM,R Van
Takeuchi R, Martijn
Rehabilitation after osteotomies around the Heerwaarden
knee.
Heerwaarden
R, Seil R
ACL rupture with open physes: Risk for
Seil R.
growth
plate and
for surgery
ACL rupture
withtiming
open physes:
Risk for
Seil R.
Thieme Verlag, 2014
Thieme Verlag, 2014
Siebold R, Dejour D, Zaffagnini S. Arthroscopic Anterior
Cruciate
Ligament
A practical Anterior
surgical
Siebold R,
Dejour D,Reconstruction :
Zaffagnini S. Arthroscopic
guide.
Cruciate Ligament Reconstruction : A practical surgical
Thieme Verlag, 2014
Springer Verlag, Heidelberg, 2014
growth plate and timing for surgery
Réparations méniscales : nouvelles
indications méniscales : nouvelles
Réparations
indications
Ligamentoplastie du croisé antérieur chez
l’enfant.
Ligamentoplastie
du croisé antérieur chez
l’enfant.
Meniscal repair.
Seil R, Hoffmann A, Pape D.
Seil R, Hoffmann A, Pape D.
Chotel F, Raux S, Seil R.
Chotel F, Raux S, Seil R.
Seil R, Hoffmann A, Gerich T, Pape D.
Seil
Romain
Orthopedy
Meniscal
repair.
ACL injuries
in children.
Seil R, Chotel
Hoffmann
F. A, Gerich T, Pape D.
Seil
Standhardt
Romain
Harald
Orthopedy
Neurosurgery
ACL injuries in children.
Seil R, Chotel F.
Boecher-Schwarz H, Standhard H
Standhardt
Harald
Neurosurgery
Boecher-Schwarz H, Standhard H
Springer Verlag, Heidelberg, 2014
guide.C, Potel JF : Techniques arthroscopiques,
Hulet
membre
inférieur.
Hulet C, Potel
JF : Techniques arthroscopiques,
Collection des Cahiers d’Enseignement
de
la SOFCOT.
Elsevier-Masson,
Paris 2014
Collection
des Cahiers
d’Enseignement
membreInstructional
inférieur.
EFORT
Lecture Book, Vol. 14
de la SOFCOT.
Springer,
Berlin,Elsevier-Masson,
Heidelberg, NewParis
York,2014
2014
membre
inférieur.
Hulet
C, Potel
membre
inférieur.
Hulet C, Potel
EFORT
Instructional
Vol.
14
Karlsson,
Doral (eds.)Lecture
Sports Book,
Injuries:
Prevention,
Diagnosis,Doral
Treatment
Rehabilitation.
Karlsson,
(eds.) and
Sports
Injuries: Prevention,
de la SOFCOT.
Elsevier-Masson,
Paris 2014
Collection
des Cahiers
d’Enseignement
de
la SOFCOT.
Elsevier-Masson,
Paris 2014
Collection
des Cahiers
d’Enseignement
pp 131-146
pp 131-146
pp 191-201
pp 191-201
Springer, Berlin, Heidelberg, New York, 2014
Diagnosis, Treatment and Rehabilitation.
Neurochirurgie
Springer, Berlin, Heidelberg, New York, 2014
Schattauer Verlag
Neurochirurgie
Schattauer Verlag
89
presentations at congresses
90
Surname
Surname
Name
Name
Service
Service
Date
Date
City
City
Title / Présentation
Allard
Serge
Pédiatrie
18.10.2014
Azagra
Allard
Juan
SergeS
Chirurgie
Pédiatrie
29.04.2014
18.10.2014
Les jeunes et le sport : JUST MOVE
Luxembourg
Asthme et sport : Franchissons les barrières ensemble
Education
Les jeunes &
etResearch
le sport :Day
JUST MOVE
Luxembourg
Azagra
Juan S
Chirurgie
Impact
system
communication
(OR1) in surgical practice and education
Asthmeof
etdigital
sport :multimedia
Franchissons
les barrières
ensemble
01-03.10.2014
29.04.2014
116e
Congrès
Français Day
de Chirurgie
Education
& Research
Paris
(F)
Luxembourg
Azzolin
Azagra
Jose
Juan S
Impact of digital multimedia system communication (OR1) in surgical practice and education
Médecine
Chirurgie physique
29-30.03.2014
01-03.10.2014
Weiskirchen
(D)
Paris (F)
Prise en charge des lombalgies
Jose
Manon
Médecine physique
Néonatologie
29-30.03.2014
16.05.2014
Rhumatologie
et Orthopédie,
116e Congrès Français
de Chirurgie
Alformec
Rhumatologie et Orthopédie,
GEFERS
Alformec
Azzolin
Bache
Weiskirchen (D)
Luxembourg
Ethique de l'organisation, éthique du management
Beissel
Bache
Jean
Manon
Cardiologie
Néonatologie
22.03.2014
16.05.2014
To
pace de
or not
to pace
Ethique
l'organisation,
éthique du management
Jean
Jean
Cardiologie
Cardiologie
22.03.2014
27.09.2014
Luxembourg
Luxembourg
To pace or not to pace
Arrêt cardiaque
Beissel
Beissel
Jean
Jean
Cardiologie
Cardiologie
27.09.2014
18.10.2014
Société
GEFERSLuxembourgeoise de
Cardiologie
Société Luxembourgeoise de
World
Heart Day Société
Cardiologie
Luxembourgeoise de Cardiologie
World Heart Day Société
Les
jeunes et le sport
: JUST MOVE
Luxembourgeoise
de Cardiologie
Luxembourg
Beissel
Beissel
Luxembourg
Luxembourg
Arrêt cardiaque
Projet scolaire : Formation Réagis et installation défibrillateurs semi automatisé
Beissel
Jean
Cardiologie
20
- 23.05.2014
18.10.2014
How
I treat?
(chairman
andet
take
home message)
Projetshould
scolaire :
Formation
Réagis
installation
défibrillateurs semi automatisé
Jean
Jean
Cardiologie
Cardiologie
20 - 23.05.2014
30.08 - 03.09.2014
EuroPCR,
Bosnia,
Les jeunesJoint
et le session
sport : JUST
MOVE
Romania and Luxembourg
EuroPCR, Joint session Bosnia,
ESC
Congress
Romania
and Luxembourg
Paris
(F)
Luxembourg
Beissel
Beissel
Paris (F)
Barcelona (Espagne)
Beissel
Beissel
Jean
Jean
Cardiologie
Cardiologie
30.08 - 03.09.2014
30.08 - 03.09.2014
ESC Congress
ESC Congress
Barcelona (Espagne)
Barcelona (Espagne)
How should I treat? (chairman and take home message)
Debates on cardiovascularimaging in patients with coronary artery disease
(chairman abstract session)
Cardiopulmonary
: new insights (chairman abstract session)
(chairman abstractresuscitation
session)
Beissel
Jean
Cardiologie
30.08 - 03.09.2014
ESC Congress
Barcelona (Espagne)
Abstract
reviewer resuscitation : new insights (chairman abstract session)
Cardiopulmonary
Berchem
Beissel
Guy
Jean
Onco-Hémato
Cardiologie
25-29.06.2014
30.08 - 03.09.2014
Barcelona (Espagne)
Clinical
discussion
Abstractcase
reviewer
Berchem
Berchem
Guy
Guy
Onco-Hémato
Onco-Hémato
25-29.06.2014
24.04.2014
16th
World Congress on
ESC Congress
Gastrointestinal Cancer
16th World Congress on
Jury
Prix Galien Cancer
Gastrointestinal
Barcelona (Espagne)
Bruxelles (B)
Clinical case discussion
Berchem
Guy
Onco-Hémato
29.04.2014
24.04.2014
Education
& Research Day
Jury Prix Galien
Luxembourg
Bruxelles (B)
Berchem
Berchem
Guy
Guy
Onco-Hémato
Onco-Hémato
29.04.2014
11.10.2015
Education & Research Day
Post-ESMO Meeting
Luxembourg
Namur (B)
Granzyme B degradation by autophagy decreases tumor cell susceptibility to natural killer-mediated
lysis under hypoxia
lysis under hypoxia
Berchem
Guy
Onco-Hémato
03.04.2014
11.10.2015
Guy
Sophie
Onco-Hémato
Gyn-Obstétrique
03.04.2014
29.04.2014
Chimiothérapie
Glioblastome et
Post-ESMO Meeting
Poumon
Chimiothérapie Glioblastome et
Education
Poumon & Research Day
Nivelles
(B)
Namur (B)
Berchem
Berglund
Berglund
Bernard
Sophie
Florian
Gyn-Obstétrique
Neurochirurgie
29.04.2014
11.2014
Luxembourg
Bad Oeynshausen (D)
Chaque cas d'asphyxie est une occasion d'apprendre, études d'évitabilité de l'asphyxie sèvère,
expérience suédoise
Poster
: Modelling
of Brainshift in Deep Brain Stimulation
expérience
suédoise
Bernard
Bernard
Florian
Florian
Neurochirurgie
Neurochirurgie
11.2014
11.2014
Bad Oeynshausen (D)
Bad Oeynshausen (D)
Poster : Modelling of Brainshift in Deep Brain Stimulation
Poster : Postoperative imaging in Deep Brain Stimulation : a controversial issue
Bernard
Bernard
Florian
Florian
Neurochirurgie
Neurochirurgie
11.2014
11.2014
Bad Oeynshausen (D)
Bad Oeynshausen (D)
Poster : Interactive hierarchical segmentation for deep brain structure identifitcation
Bernard
Berthold
Florian
Christophe
Neurochirurgie
Neurochirurgie
11.2014
11.2014
Bad Oeynshausen (D)
Bad Oeynshausen (D)
Berthold
Berthold
Christophe
Christophe
Neurochirurgie
Neurochirurgie
11.2014
Bad Oeynshausen (D)
Washington (USA)
Poster : Pulsed high frequency stimulation or thermocoagulation
in the treatment for trigeminal pain
Epidural
pulsed radiofrequenvy
(Eprf) for opain treatment-a retrospective study
in the treatment
for trigeminal pain
Berthold
Beyenburg
Christophe
Stefan
Neurochirurgie
Neurologie
14-17.05.2014
Washington (USA)
Bonn (D)
Epidural pulsed radiofrequenvy (Eprf) for opain treatment-a retrospective study
Psychiatrische Ko-Morbidität bei Erwachsenen und Kindern/Jugendlichen mit Epilepsie
Beyenburg
Beyenburg
Stefan
Stefan
Neurologie
Neurologie
14-17.05.2014
02-03.05.2014
10. Jahrestagung Deu Ges für
Neuromodulation
10.
Jahrestagung Deu Ges für
Neuromodulation
Neuromodulation
10.
Neuromodulation
Neuromodulation
10.
Neuromodulation
Neuromodulation
Biennal
meeting of the American Soc
Neuromodulation
for Ster and Functional Neurosurgery
Biennal meeting of the American Soc
Jahrestagung
Dt Gesellschaft
für
for Ster and Functional
Neurosurgery
Epileptologie
Jahrestagung Dt Gesellschaft für
Kleinwachauer
Epileptologie Epilepsiesymposium
Bonn (D)
Dresden (D)
Beyenburg
Stefan
Neurologie
01-03.10.2014
02-03.05.2014
Tag
der Epilepsie
Kleinwachauer
Epilepsiesymposium
Zürich
(CH)
Dresden
(D)
Die Darstellung der Epilepsie in den Medien
Bindl
Beyenburg
Lutz
Stefan
Néonatologie
Neurologie
27-28.05.2014
01-03.10.2014
Jahrestagung
GNPI
Tag der Epilepsie
Bonn
Zürich(D)
(CH)
Veranstaltungsvorsitz
Biver
Bindl
Armand
Lutz
Pédiatrie
Néonatologie
21.11.2014
27-28.05.2014
Liège
(B)
Bonn (D)
Biver
Boecher-Schwarz
Armand
Hans
Pédiatrie
Neurochirurgie
21.11.2014
03-06.06.2014
Liège (B)
Banff (Canada)
Abstract
: Shwachmann-Diamond Syndrome presenting as early ichthyosis and later
hypoglycemia with dermal and epidermal lipid droplet deposition
Abstract : Shwachmann-Diamond Syndrome presenting as early ichthyosis and later
Supratentorial
tanycytic
ependymoma
hypoglycemia with
dermal
and epidermal lipid droplet deposition
Boecher-Schwarz
Hans
Neurochirurgie
03-06.06.2014
Banff (Canada)
Supratentorial tanycytic ependymoma
Boecher-Schwarz
Hans
Neurochirurgie
09-10.10.2014
Wien (A)
Ungewöhnlicher Verlauf eines malignen Meningeoms
Boecher-Schwarz
Hans
Neurochirurgie
09-10.10.2014
Wien (A)
Boeker
Dagmar
Douleur
Washington (USA)
Boeker
Boisanté
Dagmar
Catherine
Douleur
Douleur
16.05.2014
Belgian
society
of pediatric
Jahrestagung
GNPI
neurology
Belgian society of pediatric
49th
Annual Congress of the
neurology
Canadian Neurological Sciences
49th Annual Congress of the
Federation
50.
Jahrestagung der
Federation
Oesterreichischen
50. Jahrestagung der
Gesellsch. Für Neurochirurgie
Oesterreichischen
Biennal meeting
of the American Soc
Gesellsch.
Für Neurochirurgie
GEFERS
for
Ster and Functional Neurosurgery
Washington (USA)
Luxembourg
Bottu
Boisanté
Jean
Catherine
Néonatologie
Douleur
02-05.07.2014
16.05.2014
NLS
formation ERC
GEFERS
Bordeaux
(F)
Luxembourg
Introduction
et direction éthique du management
Ethique de l'organisation,
Nivelles (B)
Luxembourg
91
Epileptologie
Beyenburg
Stefan
Neurologie
02-03.05.2014
Kleinwachauer Epilepsiesymposium
Dresden (D)
Beyenburg
Stefan
Neurologie
01-03.10.2014
Tag der Epilepsie
Zürich (CH)
27-28.05.2014
Jahrestagung GNPI
Bonn (D)
neurology
Liège (B)
Federation
Banff (Canada)
50.
Jahrestagung
der Day
Education
& Research
Oesterreichischen
116e Congrès Français de Chirurgie
Alformec
GEFERS
GEFERS
NLS formation ERC
Cardiologie
Congrès National de la Société
Française de Tabacologie
Cardiologie
ESC Congress
Journée thématique autour de
l'obésité
ESC Congress
8e Conférence nationale Santé
ESC Congress
Eurodiabète ESPF
Jury Prix Galien
presentations
at congresses
Bindl
Lutz
Néonatologie
Biver
Surname
92
Armand
Pédiatrie
21.11.2014
Boecher-Schwarz
Hans
Name
Service
Date
Allard
Serge
Pédiatrie
18.10.2014
Boecher-Schwarz
Azagra
Hans
Juan S
Neurochirurgie
Chirurgie
09-10.10.2014
29.04.2014
Azagra
Juan S
Chirurgie
01-03.10.2014
Azzolin
Boeker
Jose
Dagmar
Médecine physique
Douleur
29-30.03.2014
Bache
Boisanté
Beissel
Bottu
Manon
Catherine
Jean
Jean
Néonatologie
Douleur
Cardiologie
Néonatologie
16.05.2014
16.05.2014
22.03.2014
02-05.07.2014
Charpentier
Beissel
Catherine
Jean
Pneumologie
Cardiologie
23-25.10.2014
27.09.2014
Charpentier
Beissel
Catherine
Jean
Pneumologie
Cardiologie
27.09.2014
18.10.2014
Beissel
Dadoun
Jean
Frédéric
Cardiologie
Endocrinologie
20 - 23.05.2014
22.03.2015
Beissel
Dadoun
Jean
Frédéric
Cardiologie
Endocrinologie
30.08 - 03.09.2014
23.05.2014
Beissel
D'Alimonte
Beissel
de Beaufort
Berchem
de Beaufort
Jean
Julia
Jean
Carine
Guy
Carine
Cardiologie
Pédopsychiatrie
Cardiologie
Pédiatrie
Onco-Hémato
Endocrinologie péd
30.08 - 03.09.2014
05.11.2014
30.08 - 03.09.2014
17-20.09.2014
25-29.06.2014
29.04.2014
de Beaufort
Berchem
de Beaufort
Berchem
De La Fuente Garcia
Carine
Guy
Carine
Guy
Isabel
Endocrinologie péd
Onco-Hémato
Pédiatrie
Onco-Hémato
Pédiatrie
18.10.2014
24.04.2014
01-06.09.2014
29.04.2014
05.2015
Berchem
De Nadai
Berchem
Delagardelle
Guy
Serge
Guy
Charles
Onco-Hémato
Gériatrie
Onco-Hémato
Cardiologie
11.10.2015
16.05.2015
03.04.2014
28.04.2014
Berglund
Despontin
Sophie
Karine
Gyn-Obstétrique
Pédiatrie
29.04.2014
21.11.2014
Bernard
Diederich
Florian
Nico
Neurochirurgie
Neurologie
11.2014
01-04.10.2014
Bernard
Dooms
Florian
Georges
Neurochirurgie
Radiologie
11.2014
11.2014
Bernard
Dooms
Florian
Georges
Neurochirurgie
Radiologie
11.2014
11.2014
Berthold
Dooms
Christophe
Georges
Neurochirurgie
Radiologie
11.2014
03-06.06.2014
Berthold
Christophe
Neurochirurgie
Droste
Beyenburg
Droste
Dirk
Stefan
Dirk
Neurologie
Neurologie
Neurologie
12.03.2014
14-17.05.2014
Droste
Beyenburg
Dirk
Stefan
Neurologie
27.09.2014
02-03.05.2014
Beyenburg
Droste
Bindl
Droste
Biver
Stefan
Dirk
Lutz
Dirk
Armand
Neurologie
Neurologie
Néonatologie
Neurologie
Pédiatrie
01-03.10.2014
31.05.2014
27-28.05.2014
29.04.2014
21.11.2014
Duhem
Boecher-Schwarz
Duhem
Caroline
Hans
Caroline
Onco-Hémato
Neurochirurgie
Onco-Hémato
22-29.05.2014
03-06.06.2014
28.04.2014
Duhem
Boecher-Schwarz
Caroline
Hans
Onco-Hémato
Neurochirurgie
22.11.2014
09-10.10.2014
Duhem
Caroline
Onco-Hémato
11.10.2015
Duhem
Boeker
Fogen
Caroline
Dagmar
Frédéric
Onco-Hémato
Douleur
Soins palliatifs
13.06.2014
Gerich
Boisanté
Torsten
Catherine
Traumatologie
Douleur
22.03.2014
16.05.2014
Bottu
Jean
Néonatologie
02-05.07.2014
Charpentier
Gerich
Catherine
Torsten
Pneumologie
Traumatologie
23-25.10.2014
04-06.12.2016
Charpentier
Goergen
Catherine
Martine
Pneumologie
Chirurgie
27.09.2014
30.04-03.05.2014
Dadoun
Frédéric
Endocrinologie
22.03.2015
Goergen
Martine
Chirurgie
23.05.2014
Neurochirurgie
03-06.06.2014
12.11.2014
ESPID
City
Luxembourg
Wien
(A)
Luxembourg
Ungewöhnlicher
einessystem
malignen
Meningeoms(OR1) in surgical practice and education
Impact of digital Verlauf
multimedia
communication
Paris (F)
Weiskirchen (D)
Washington (USA)
Luxembourg
Luxembourg
Luxembourg
Bordeaux (F)
Introduction et direction
Clermont-Ferrand (F)
Luxembourg
Présidence session : sevrage et prises en charge intégrées
Arrêt cardiaque
Luxembourg
Luxembourg
E-cigarette : Qu'en penser en septembre 2014?
Paris (F)
Luxembourg
Regards croisés et questions ouvertes
Barcelona (Espagne)
Luxembourg
L'aspect médical de l'obésité: risques et conséquences
Barcelona (Espagne)
Luxembourg
Barcelona (Espagne)
Dublin (IRL)
Barcelona (Espagne)
Luxembourg
Cardiopulmonary resuscitation : new insights (chairman abstract session)
coordinateur
Abstract reviewer
Luxembourg
Bruxelles (B)
Toronto (Canada)
Luxembourg
Dublin (IRL)
Diabète et sport : No slow motion
Post-ESMO Meeting
GEFERS
Sport-thérapie & maladies
Poumon
chroniques
neurology
German Genetic Society, Parkinson
Neuromodulation
Symposium
Neuromodulation
Neuromodulation
Neuromodulation
Neuromodulation
Neuromodulation
Federation
Südwestdeutscher Schlaganfalltag
Conseil national des Femmes
Epileptologie
Namur (B)
Luxembourg
Nivelles (B)
Luxembourg
Microbiome and type 1 diabetes
chair and secretary general
Protection
lysis
under against
hypoxiavaccine preventable diseases (VPD) after chemotherapy for
Acute Lymphoblastic Leukemia (ALL)
Apport thérapeutique du sport aux maladies cardiovasculaires et cancéreuses: mécanisme commun
Bad Oeynshausen (D)
Luxembourg
Abstract : Shwachmann-Diamond
Syndrome presenting as early ichthyosis and later
expérience
suédoise
chairperson + poster
Bad Oeynshausen (D)
Bad Oeynshausen (D)
Poster : DTI Fibretracking of the arcuate fascicle in Neuronavigation for Brain tumors
Bad Oeynshausen (D)
Bad Oeynshausen (D)
Bad Oeynshausen (D)
Banff (Canada)
Supratentorial
tanycytic
ependymoma
in
the treatment
for trigeminal
pain
Washington (USA)
Kaiserslautern (D)
Bonn (D)
Luxembourg
Neue Diagnosemethoden beim Schlaganfall: Vorhofflimmern
Les femmes et les hommes face à l'accident vasculaire cérébral
World Heart Day
Société
Kleinwachauer
Epilepsiesymposium
Tag der Epilepsie
Update Schlaganfall
Jahrestagung GNPI
neurology
SIFEM 2014
Sport-thérapie
& maladies
Canadian
Neurological
Sciences
chroniques
Federation
Luxembourg
Dresden
(D)
Den Hireschlag - En Noutfall
Zürich (CH)
Luxembourg
Bonn (D)
Luxembourg
Liège (B)
Ernährung und Bewegung zur Prophylaxe zerebro-vaskulärer Erkrankungen (chairman)
A daily glass of red wine associated with lifestyle changes independently improves blood lipids in
patients with carotid arteriosclerosis: results from a radomized controlled trial
Femmes
et cancerder
50.
Jahrestagung
Oesterreichischen
Post-ESMO Meeting
3e Congrès Français Cancer inzta..
AEKSter
Saarland
for
and Functional Neurosurgery
Luxembourg
Wien
(A)
Reims (F)
Washington (USA)
Tholey (D)
Moderation
Symposium Complication
GEFERS
management in geriatric
NLS
formation
ERC
shoulder
fractures
Congrès
National
Société
Congrès annuel dede
lala
Société
Française
Tabacologie
Française de
d'Arthroscopie
Luxembourg
Luxembourg
chairman
Ethique
de l'organisation, éthique du management
Bordeaux (F)
Clermont-Ferrand
(F)
Luxembourg
Présidence
session
: sevrage
et prises
en charge
intégrées
Arthroscopic
treatment
of articular
fractures
of the
lower limb
Luxembourg
Bruxelles
(B)
Cardiologie
Luxembourg
E-cigarette
: Qu'en
enBypass?
septembre
2014? Aspects : Defining length/size of gastric ouchg and
What
is perfect
RNYpenser
Gastric
Technical
loops.
Time
reduced
surgery
by newouvertes
devices.
Regards
croisés
et questions
Luxembourg
La chirurgie bariatrique – quand et pour qui?
World
Day Société et
IFS
EC Heart
2014 (moderation
presentations)
Luxembourg
Liège (B)
Bruxelles (B)
Banff (Canada)
Luxembourg
Sport et cancer: pourquoi, pour qui et comment?
Cancer du sein : quoi
de eines
neuf?malignen Meningeoms
Ungewöhnlicher
Verlauf
Namur (B)
93
Duhem
Caroline
Onco-Hémato
22.11.2014
Femmes et cancer
Luxembourg
Duhem
Caroline
Onco-Hémato
11.10.2015
Post-ESMO Meeting
Namur (B)
Duhem
Caroline
Onco-Hémato
13.06.2014
3e Congrès Français Cancer inzta..
Reims (F)
12.11.2014
AEK Saarland
Tholey (D)
Luxembourg
chairman
City
presentations
at congresses
Fogen
Frédéric
Soins palliatifs
94
Cancer du sein : quoi de neuf?
Moderation
Gerich
Torsten
Traumatologie
22.03.2014
Surname
Name
Service
Date
Symposium Complication
management in geriatric
shoulder fractures
Gerich
Allard
Torsten
Serge
Traumatologie
Pédiatrie
04-06.12.2016
18.10.2014
Congrès annuel de la Société
Les jeunesd'Arthroscopie
et le sport : JUST MOVE
Française
Luxembourg
Luxembourg
Arthroscopic treatment of articular fractures of the lower limb
Azagra
Goergen
Juan
S
Martine
Chirurgie
29.04.2014
30.04-03.05.2014
Juan S
Chirurgie
01-03.10.2014
Education
& (moderation
Research Dayet
IFS EC 2014
presentations)
Luxembourg
Bruxelles (B)
Azagra
Azzolin
Goergen
Jose
Martine
Médecine physique
Chirurgie
29-30.03.2014
23.05.2014
Weiskirchen (D)
Luxembourg
Bache
Gomes Ferreira
Beissel
Gomes Ferreira
Manon
Cindy
Jean
Cindy
Néonatologie
Chir Ped
Cardiologie
Chir Ped
16.05.2014
22-26.07.2014
22.03.2014
01-03.10.2014
Luxembourg
Edinbourgh (Ecosse)
Luxembourg
Bratislava (SK)
Laparoscopic Mesh Rectopexy for Rectal Prolapse
A Rare Case Of Traumatic Abdominal Wall Hernia Treated By Laparoscopy
Gomes Ferreira
Beissel
Cindy
Jean
Chir Ped
Cardiologie
24.03.2014
27.09.2014
Paris (F)
Luxembourg
Hernie diaphragmatique et thoracoscopique
Arrêt cardiaque
Beissel
Groben
Beissel
Jean
Laurent
Jean
Cardiologie
Cardiologie
Cardiologie
18.10.2014
22.03.2014
20 - 23.05.2014
Luxembourg
Luxembourg
Paris (F)
Pacing cardiaque et resynchronisation
Hana
Beissel
Ardian
Jean
Neurochirurgie
Cardiologie
11.2014
30.08 - 03.09.2014
Alformec
l'obésité
GEFERS
Congres I.P.E.G.
4th ESPES Annual Congress
Cardiologie
Journée Centre de Référence des
Hernies Diaphragmatiques
Congénitales
EuroPCR,
Joint session Bosnia,
Cardiologie
ESC
Congress
Neuromodulation
Impact
digitalRNY
multimedia
system communication
(OR1)
in surgical
practiceof
and
education
What isof
perfect
Gastric Bypass?
Technical Aspects
: Defining
length/size
gastric
ouchg and
loops.
Time reduced surgery by new devices.
La chirurgie bariatrique – quand et pour qui?
Bad Oeynshausen (D)
Barcelona (Espagne)
Hana
Beissel
Ardian
Jean
Neurochirurgie
Cardiologie
03-06.06.2014
30.08 - 03.09.2014
Banff (Canada)
Barcelona (Espagne)
Beissel
Hana
Berchem
Jean
Ardian
Guy
Cardiologie
Neurochirugie
Onco-Hémato
30.08 - 03.09.2014
26.02-01.03.2014
25-29.06.2014
ESC
Congress
Canadian
Neurological Sciences
Federation
ESC
Congress
Hédo
Paul
Psychiatrie
05.11.2014
Berchem
Hellers
Guy
Joe
Onco-Hémato
Chirurgie plastique
24.04.2014
23.05.2014
Berchem
Hentges
Guy
François
Onco-Hémato
Immuno-Allergologie
29.04.2014
29.04.2014
Berchem
Hertel
Guy
Frank
Onco-Hémato
Neurochirurgie
11.10.2015
Berchem
Hertel
Guy
Frank
Onco-Hémato
Neurochirurgie
03.04.2014
Hertel
Berglund
Frank
Sophie
Neurochirurgie
Gyn-Obstétrique
11.2014
29.04.2014
Hertel
Bernard
Frank
Florian
Neurochirurgie
Neurochirurgie
11.2014
11.2014
Hertel
Bernard
Frank
Florian
Neurochirurgie
Neurochirurgie
11.2014
11.2014
Hertel
Bernard
Frank
Florian
Neurochirurgie
Neurochirurgie
11.2014
11.2014
Hertel
Berthold
Frank
Christophe
Neurochirurgie
Neurochirurgie
11.2014
11.2014
Hertel
Berthold
Frank
Christophe
Neurochirurgie
Neurochirurgie
11.2014
Hertel
Beyenburg
Frank
Stefan
Neurochirurgie
Neurologie
03-06.06.2014
14-17.05.2014
Beyenburg
Hertel
Stefan
Frank
Neurologie
Neurochirurgie
02-03.05.2014
Beyenburg
Hertel
Bindl
Stefan
Frank
Lutz
Neurologie
Neurochirurgie
Néonatologie
01-03.10.2014
Biver
Hertel
Armand
Frank
Pédiatrie
Neurochirurgie
21.11.2014
29-30.03.2014
Boecher-Schwarz
Hertel
Hans
Frank
Neurochirurgie
Neurochirurgie
03-06.06.2014
Hertz
Boecher-Schwarz
Pierre
Hans
Cellule DIM
Neurochirurgie
20-21.11.2014
09-10.10.2014
Hsie
Boeker
Husch
Julien
Dagmar
Andreas
ORL
Douleur
Neurochirurgie
29.04.2014
Boisanté
Husch
Bottu
Catherine
Andreas
Jean
Douleur
Neurochirurgie
Néonatologie
16.05.2014
11.2014
02-05.07.2014
Charpentier
Husch
Catherine
Andreas
Pneumologie
Neurochirurgie
23-25.10.2014
11.2014
Charpentier
Husch
Catherine
Andreas
Pneumologie
Neurochirurgie
27.09.2014
11.2014
Dadoun
Kerschen
Frédéric
Philippe
Endocrinologie
Neurologie
22.03.2015
28.01.2014
27-28.05.2014
11.2014
Gastrointestinal
Cancer Santé
8e Conférence nationale
Jury
Prixthématique
Galien
Journée
autour de
l'obésité & Research Day
Education
Paris (F)
Barcelona (Espagne)
Paris (F) (Espagne)
Barcelona
Luxembourg
Abstract reviewer
présentation
d'un E-poster
Clinical
case discussion
Dispositif de soins au GD de Luxembourg : ressources et défis.
Bruxelles
(B)
Luxembourg
La chirurgie plastique après Bypass/Sleeve
Luxembourg
Luxembourg
lysis
under hypoxia
Identification
and isolation of a FEL D1-like molecule as a major rabbit antigen
Post-ESMO
Meeting of Neurosurgery
10th Asian Congress
Namur
Astana (B)
(Kasachstan)
Deep Brain Stimulation (DBS)-a personal series of 501 implantations
Chimiothérapie
Glioblastome
et
10th Asian Congress
of Neurosurgery
Poumon
Education
& Research Day
Neuromodulation
Nivelles
(B)
Astana (Kasachstan)
Electromagnetic Navigation for brain and skullbase surgery
Bad Oeynshausen (D)
Luxembourg
10.
Neuromodulation
Neuromodulation
10.
Neuromodulation
Neuromodulation
10.
Neuromodulation
Neuromodulation
10.
Neuromodulation
Neuromodulation
Biennal
meeting of the American Soc
Neuromodulation
Jahrestagung
Dt Gesellschaft
für
Canadian Neurological
Sciences
Epileptologie
Federation
Bad Oeynshausen (D)
Bad Oeynshausen (D)
Networks, Feedback and Deep Brain Stimulation-Insights in New Trends
Bad Oeynshausen (D)
Bad Oeynshausen (D)
Bad Oeynshausen (D)
Bad Oeynshausen (D)
Bad Oeynshausen (D)
Bad Oeynshausen (D)
Bad Oeynshausen (D)
Washington (USA)
Poster
: Pulsed high
frequency stimulation
or thermocoagulation
in the treatment
for trigeminal
pain
Banff (Canada)
Bonn (D)
Kleinwachauer
Congresso Soc Epilepsiesymposium
Ster Neurochir Fonct
de Brazil
Tag
der Epilepsie
Dresden
(D)
Sao Paulo
(Brazil)
Microrecording (MER) in Deep Brain Stimulation (DBS) and stereotactic lesioning (SL)
Zürich (CH)
Washington
(USA)
Bonn
(D)
Liège (B)
Weiskirchen (D)
Prise en chargewith
desdermal
lombalgies
hypoglycemia
and epidermal lipid droplet deposition
Banff (Canada)
Xi'an (China)
3D-susceptibility-weighted MRI for target and trajectory planning in DBS-surgery(Is Gadolinium still necessary?)
Saint Malo
Wien
(A) (F)
Utilisation des données
la documentation
soignante pour l'évaluation de la charge en
Ungewöhnlicher
Verlauf de
eines
malignen Meningeoms
soins et le pilotage des ressources soignantes au CHL et comparaison avec le PMSI
français au travers de l'ENCC
Luxembourg(USA)
Washington
Bad Oeynshausen (D)
Smell andpulsed
Taste radiofrequenvy
Clinic
Epidural
(Eprf) for opain treatment-a retrospective study
Luxembourg
Bad Oeynshausen
(D)
Bordeaux
(F)
Poster : Modelling
Introduction
et direction
Bad Oeynshausen (D)
Luxembourg
Bad Oeynshausen (D)
Luxembourg
Paris (F)
Encéphalites auto-immunes
Biennal
meeting
of the American Soc
Jahrestagung
GNPI
neurology
Alformec
2nd meeting
of the International
Canadian
Neurological
Sciences Soc
for miniinvasive Neurosurgery
Federation
Séminaire
ENCC 2014
50.
Jahrestagung
der
Oesterreichischen
Education
& Research
Biennal
meeting
of theDay
American Soc
for
Ster and Functional
Neurosurgery
10. Jahrestagung
Deu Ges
für
Neuromodulation
GEFERS
10. Jahrestagung
Deu Ges für
NLS
formation ERC
Neuromodulation
10.
Jahrestagung
Deu Ges für
Française
de Tabacologie
Neuromodulation
10.
Jahrestagung Deu
Ges für
Luxembourgeoise
de Cardiologie
Neuromodulation
Staff
Médecine Intene, CHU PitiéCardiologie
Salpétrière
95
for miniinvasive Neurosurgery
Hertz
Pierre
(Is Gadolinium still necessary?)
Cellule DIM
20-21.11.2014
Séminaire ENCC 2014
Saint Malo (F)
Utilisation des données de la documentation soignante pour l'évaluation de la charge en
soins et le pilotage des ressources soignantes au CHL et comparaison avec le PMSI
français au travers de l'ENCC
Smell and Taste Clinic
presentations at congresses
Hsie
Julien
ORL
29.04.2014
Luxembourg
Husch
Andreas
Name
Neurochirurgie
Service
11.2014
Date
Neuromodulation
Bad Oeynshausen (D)
City
Husch
Allard
Andreas
Serge
Neurochirurgie
Pédiatrie
11.2014
18.10.2014
Neuromodulation
Bad Oeynshausen (D)
Luxembourg
Azagra
Husch
Juan
S
Andreas
Chirurgie
Neurochirurgie
29.04.2014
11.2014
Impact
digital multimedia
system
communication
(OR1): aincontroversial
surgical practice
Poster :of
Postoperative
imaging
in Deep
Brain Stimulation
issueand education
Juan S
Andreas
Jose
Chirurgie
Neurochirurgie
Médecine physique
01-03.10.2014
11.2014
29-30.03.2014
Paris (F)
Bad Oeynshausen (D)
Weiskirchen (D)
Kerschen
Bache
Philippe
Manon
Neurologie
Néonatologie
28.01.2014
16.05.2014
Paris (F)
Luxembourg
Encéphalites auto-immunes
Beissel
Koy
Jean
Jan
Cardiologie
Neurochirurgie
22.03.2014
Luxembourg
Washington (USA)
Epidural pulsed radiofrequency (Eprf) for pain treatment-a retrospective study
Beissel
Kreins
Jean
Nathalie
Cardiologie
Pédiatrie
27.09.2014
20-21.03.2014
Luxembourg
Brugge (B)
Arrêt cardiaque
Krüger
Beissel
Krüger
Beissel
Le Saint
Rejko
Jean
Rejko
Jean
Laurent
Neurologie
Cardiologie
Neurologie
Cardiologie
Psychiatrie
17-19.09.2014
18.10.2014
10-13.09.2014
20 - 23.05.2014
09.2014
Education
& Research
Day für
10. Jahrestagung
Deu Ges
Neuromodulation
Neuromodulation
Alformec
Staff Médecine Intene, CHU PitiéGEFERS
Salpétrière
Cardiologie
Congrès Société Belge de Pédiatrie
Luxembourg
Bad Oeynshausen (D)
Azagra
Husch
Azzolin
München (D)
Luxembourg
Vancouver (CDN)
Paris (F)
Besançon (F)
Mouvement anormaux
Maladie de Parkinson
Le suicide de la personne âgée au GD de Luxembourg : épidémiologie et psychopathologies
Beissel
Le Saint
Jean
Laurent
Cardiologie
Psychiatrie
30.08 - 03.09.2014
05.11.2014
Barcelona (Espagne)
Luxembourg
(chairman
session)
Le suicide abstract
de la personne
âgée au GD de Luxembourg : épidémiologie et facteurs de risque
Beissel
Le Saint
Jean
Laurent
Cardiologie
Psychiatrie
30.08
- 03.09.2014
26-27.02.2014
Cardiopulmonary
resuscitation
insights
L'impact traumatique
du suicide: new
sur les
proches
Jean
Frédéric
Guy
Cardiologie
Cardiologie
Onco-Hémato
30.08 - 03.09.2014
18.10.2014
25-29.06.2014
Barcelona (Espagne)
Luxembourg
Barcelona (Espagne)
Abstract reviewer
Echographie cardiaque et HTAP? Crtitères pronostics échographiques de l'HTAP et place du
dépistage échagraphique de l'HTAP
Leches
Berchem
Maazoun
Berchem
Marguerite
Guy
Yamen
Guy
Eval & Reed
Onco-Hémato
Cardiologie
Onco-Hémato
26-29.06.14
24.04.2014
10-12.04.2014
29.04.2014
ESC
Congressnationales de
VIII Journées
Prévention du Suicide
ESC Congress
L'hypertension arterielle pulmonaire
(HTAP)
Die Zukunft der Neurorehabilitation
Jury Prix Galien
4èmes Journées Nationales du GACI
2014
Barcelona
(Espagne)
Luxembourg
Beissel
Lebrun
Berchem
Bad Aibling (D)
Bruxelles (B)
Paris (F)
Luxembourg
Was kommt nach der Reha? Das luxemburgische Modell
Max
Berchem
Martin
Guy
Neurochirurgie
Onco-Hémato
18-20.02.2014
11.10.2015
Bremen (D)
Namur (B)
Berchem
Max
Guy
Martin
Onco-Hémato
Neurochirurgie
03.04.2014
16-17.01.2014
Max
Berglund
Metz
Martin
Sophie
René
Neurochirurgie
Gyn-Obstétrique
Neurologie
01-03.05.2014
29.04.2014
24.10.2014
Bernard
Morisset
Florian
Martine
Neurochirurgie
Immuno-Allergologie
11.2014
16-18.04.2014
24. Symposium Intensivmedizin
Post-ESMO Meeting
(Leitung)
HIFIT 2014 (Moderation)
Poumon
5th annual meeting of NWAC
World Palliative Care Day 2014,
Palliative Care and Neurology
Neuromodulation
Congrès francophone d'Allergologie
Bernard
Mühe
Florian
Annette
Neurochirurgie
Psychiatrie
11.2014
14-18.06.2014
Bernard
Najfeld
Florian
Michael
Neurochirurgie
Orthopédie
11.2014
14-17.05.2014
Nührenbörger
Berthold
Christian
Christophe
Orthopédie
Neurochirurgie
04-06.12.2016
11.2014
Nührenbörger
Berthold
Christian
Christophe
Orthopédie
Neurochirurgie
04-06.12.2016
Panosetti
Beyenburg
Panosetti
Eugène
Stefan
Eugène
ORL
Neurologie
ORL
29.03.2014
14-17.05.2014
03.04.2014
Pape
Beyenburg
Pape
Beyenburg
Dietrich
Stefan
Dietrich
Stefan
Orthopédie
Neurologie
Orthopédie
Neurologie
23.01.2014
02-03.05.2014
04-06.12.2014
01-03.10.2014
Bindl
Pape
Biver
Lutz
Dietrich
Armand
Néonatologie
Orthopédie
Pédiatrie
27-28.05.2014
04-06.12.2016
21.11.2014
Pape
Boecher-Schwarz
Dietrich
Hans
Orthopédie
Neurochirurgie
04-06.12.2016
03-06.06.2014
Pape
Dietrich
Orthopédie
04-06.12.2016
Boecher-Schwarz
Pape
Hans
Dietrich
Neurochirurgie
Orthopédie
09-10.10.2014
29.04.2014
Pauly
Fernand
Eval & Reed
23.09.2014
Pauly
Boeker
Fernand
Dagmar
Eval & Rééducation
Douleur
24.04.2014
Les enjeux
éthiques
de American
la médecine
Biennal
meeting
of the
Soc
prénatale
for
Luxembourg(USA)
Washington
Un regard
postnatal
sur la médecine
prénatale
Epidural
pulsed
radiofrequenvy
(Eprf)
for opain treatment-a retrospective study
Philippe
Boisanté
Paul
Catherine
Chir Ped
Douleur
02-05.03.2014
16.05.2014
Masterchirurgie miniinvasive
GEFERS
Bologna (I)
Luxembourg
Philippe
Bottu
Paul
Jean
Chir Ped
Néonatologie
01-03.10.2014
02-05.07.2014
4th ESPES
Annual
NLS
formation
ERCCongress
Bratislava (F)
(SK)
Bordeaux
Congenital Mid-Ureteral
Introduction
et directionStenosis And Its Laparoscopic Treatment
Philippe
Charpentier
Paul
Catherine
Chir Ped
Pneumologie
22-27.07.2014
23-25.10.2014
Congres National
I.P.E.G. de la Société
Congrès
Edinbourgh (Ecosse)
Clermont-Ferrand
(F)
Three-D Reconstruction
Aided
Multisegmentectomy
as a Lung Sparing Procedure in
Présidence
session : sevrage
et Thoracoscopic
prises en charge
intégrées
a Case of Multilobar Pulmonary CCAM (poster)
Pignoloni
Charpentier
Claudio
Catherine
Pédopsychiatrie
Pneumologie
22-24.1.2014
27.09.2014
Modération
Le travail
avecen
les
familles 2014?
E-cigarette :: Qu'en
penser
septembre
Charles
Frédéric
Psychiatrie
Endocrinologie
23.05.2014
22.03.2015
12e
Congrès
World
Heart de
Dayl'Encéphale
Société
Luxembourgeoise
deautour
Cardiologie
Journée
thématique
de
Paris
(F)
Luxembourg
Pull
Dadoun
Luxembourg
Luxembourg
Bilan psychiatrique dans l'obésité: à quoi ça sert?
Pull
Charles
Psychiatrie
10.05.2014
Mondorf-les-Bains
Angoisse
Surname
96
Romania
and de
Luxembourg
XXX congrès
la Société de
Psychogériatrie, SPLF
ESC Congress
8e Conférence nationale Santé
Nivelles (B)
Heidelberg (D)
L'angioplastie complexe : un conflit de génération ?
lysis under hypoxia
Die drei wichtigsten Studien über Komplikationen in der Intensivmedizin.
Grundlagen der Lagerungstherapie.
Spezielle Pathophysiologie der Beatmung
Wien (A)
Luxembourg
Luxembourg
ALI-The Expert's Concept of Ventilation
expérience
suédoise
Etat des lieux:
coma, état végétatif chronique, état pauci-relationnel
Bad Oeynshausen (D)
Paris (F)
Animation atelier, présentation orale, chairman
10.
Jahrestagung
Ges fürHealth
World
AssociationDeu
of Mental
Neuromodulation
Bad
Oeynshausen
(D)
Edinburgh
(Ecosse)
Poster
: Postoperative
imaging
Deep Brain
Stimulation
Relational
Mother-Baby
Care inin
a general
Public
Hospital : a controversial issue
Centre Hospitalier de Luxembourg (poster)
10.
Jahrestagung
ESSKA
Kongress Deu Ges für
Neuromodulation
10.
Jahrestagung
Deu Ges für
Française
d'Arthroscopie
Neuromodulation
Biennal
meeting
of the American Soc
Française
d'Arthroscopie
Congrès Saar-Lor-Lus
Congrès annuel de l'AFOP
Epileptologie
Bad
Oeynshausen
Amsterdam
(NL) (D)
Luxembourg
Bad Oeynshausen (D)
Results for anterior cruciate ligament reconstructions: which objectives should be reached?
Clinical and scientific perspective for the future of sports medicine in Luxemburg
Tag der Epilepsie
Française d'Arthroscopie
Jahrestagung GNPI
Belgian
society
of pediatric
Française
d'Arthroscopie
neurology
49th
Annual
Congress of the
Française
d'Arthroscopie
Federation
Oesterreichischen
Réunion RSL
Gesellsch.
Für Neurochirurgie
l'obésité
Cardiologie
83 journée d'atelier en Médecine
Luxembourg
Washington (USA)
Homburg (D)
Bonn (D)
Toulouse (F)
Homburg (D)
Dresden (D)
Luxembourg
Zürich (CH)
Sportorthopädie "Obere Extremität"
The preclinical sheep model of high tibial osteotomy
Luxembourg
Banff (Canada)
Osteotomy and knee arthroscopy
Luxembourg
Ankle OCD of the children
Wien (A)
Luxembourg
Postarthroscopic osteonecrosis of the knee – fact or fiction?
Bonn (D)
Luxembourg
Liège (B)
Gilly (B)
97
Pape
Dietrich
Orthopédie
29.04.2014
Luxembourg
Pauly
Fernand
Eval & Reed
23.09.2014
Réunion RSL
Gilly (B)
24.04.2014
Les enjeux éthiques de la médecine
prénatale
Luxembourg
02-05.03.2014
Masterchirurgie miniinvasive
Bologna (I)
Pauly
Fernand
Eval & Rééducation
presentations
at congresses
Philippe
Surname
Philippe
98
Paul
Chir Ped
Name
Paul
Service
Chir Ped
Date
01-03.10.2014
Philippe
Allard
Paul
Serge
Chir Ped
Pédiatrie
Azagra
Pignoloni
Juan
S
Claudio
Azagra
Pull
Juan
S
Charles
Azzolin
Pull
Postarthroscopic osteonecrosis of the knee – fact or fiction?
Un regard postnatal sur la médecine prénatale
4th ESPES Annual Congress
City
Bratislava
(SK)
Title
/ Présentation
Congenital
Mid-Ureteral Stenosis And Its Laparoscopic Treatment
22-27.07.2014
18.10.2014
Congres I.P.E.G.
Edinbourgh (Ecosse)
Luxembourg
Three-D Reconstruction Aided Thoracoscopic Multisegmentectomy as a Lung Sparing Procedure in
Asthme
etMultilobar
sport : Franchissons
barrières ensemble
a
Case of
Pulmonary les
CCAM (poster)
Chirurgie
Pédopsychiatrie
29.04.2014
22-24.1.2014
Education
& Research
Day
12e Congrès
de l'Encéphale
Luxembourg
Paris (F)
Impact
of digital
multimedia
system
communication (OR1) in surgical practice and education
Modération
: Le travail
avec les
familles
Chirurgie
Psychiatrie
01-03.10.2014
23.05.2014
Paris
(F)
Luxembourg
Bilan psychiatrique dans l'obésité: à quoi ça sert?
Jose
Charles
Médecine physique
Psychiatrie
29-30.03.2014
10.05.2014
116e
Congrès
Français
de Chirurgie
Journée
thématique
autour
de
l'obésité
Rhumatologie
et Orthopédie,
Weiskirchen (D)
Mondorf-les-Bains
Angoisse
Bache
Ries
Beissel
Manon
Fernand
Jean
Néonatologie
Onco-Hémato
Cardiologie
16.05.2014
22.11.2014
22.03.2014
Luxembourg
Luxembourg
Luxembourg
Saleh
Sport
et or
Cancer
To
pace
not to pace
Christian
Neurologie
11.2014
Beissel
Saleh
Jean
Christian
Cardiologie
Neurologie
27.09.2014
11.2014
Beissel
Scalais
Beissel
Jean
Emmanuel
Jean
Cardiologie
Neuropédiatrie
Cardiologie
18.10.2014
21.11.2014
20
- 23.05.2014
Schlesser
Beissel
Marc
Jean
Pneumologie
Cardiologie
30.08 - 03.09.2014
Belgian society
of pediatric
EuroPCR,
Joint session
Bosnia,
neurologyand Luxembourg
Romania
European
Respiratory Society
ESC
Congress
Beissel
Schlesser
Beissel
Jean
Marc
Jean
Cardiologie
Pneumologie
Cardiologie
30.08 - 03.09.2014
06-10.09.14
30.08 - 03.09.2014
ESC Congress
Annual European Congress of
ESC
CongressERS
Pulmonology
Barcelona (Espagne)
München (D)
Barcelona (Espagne)
Berchem
Schlesser
Guy
Marc
Onco-Hémato
Pneumologie
25-29.06.2014
07.11.2014
Barcelona (Espagne)
Paris (F)
Berchem
Schlesser
Berchem
Guy
Marc
Guy
Onco-Hémato
Pneumologie
Onco-Hémato
24.04.2014
16-21.05.2014
29.04.2014
Gastrointestinal
8e Congrès de laCancer
Société française
de tabacologie
Jury
Prix Galien
Berchem
Schmitz
Berchem
Schmitz
Guy
Bernd
Guy
Bernd
Onco-Hémato
Anesthésie
Onco-Hémato
Anesthésie
11.10.2015
06-08.02.2014
03.04.2014
07-11.05.2014
Seifert
Berglund
Seil
Kerstin
Sophie
Romain
Cardiologie
Gyn-Obstétrique
Orthopédie
18.10.2014
29.04.2014
04-06.12.2014
Bernard
Seil
Florian
Romain
Neurochirurgie
Orthopédie
11.2014
04-06.12.2014
Bernard
Florian
Neurochirurgie
11.2014
Bernard
Seil
Florian
Romain
Neurochirurgie
Orthopédie
11.2014
04-06.12.2016
Berthold
Seil
Christophe
Romain
Neurochirurgie
Orthopédie
11.2014
04-06.12.2016
Berthold
Seil
Christophe
Romain
Neurochirurgie
Orthopédie
04-06.12.2016
Beyenburg
Seil
Stefan
Romain
Neurologie
Orthopédie
14-17.05.2014
02.2014
Beyenburg
Seil
Beyenburg
Stefan
Romain
Stefan
Neurologie
Orthopédie
Neurologie
02-03.05.2014
02.2014
01-03.10.2014
Bindl
Seil
Biver
Lutz
Romain
Armand
Néonatologie
Orthopédie
Pédiatrie
27-28.05.2014
02.2014
21.11.2014
Seil
Boecher-Schwarz
Romain
Hans
Orthopédie
Neurochirurgie
02.2014
03-06.06.2014
Seil
Romain
Orthopédie
02.2014
Boecher-Schwarz
Seil
Hans
Romain
Neurochirurgie
Orthopédie
09-10.10.2014
02.2014
Seil
Boeker
Romain
Dagmar
Orthopédie
Douleur
04-06.12.2016
Seil
Boisanté
Romain
Catherine
Orthopédie
Douleur
03.2014
16.05.2014
Bottu
Seil
Charpentier
Jean
Romain
Catherine
Néonatologie
Orthopédie
Pneumologie
02-05.07.2014
03.2014
23-25.10.2014
Seil
Charpentier
Romain
Catherine
Orthopédie
Pneumologie
03.2014
27.09.2014
Seil
Dadoun
Romain
Frédéric
Orthopédie
Endocrinologie
03.2014
22.03.2015
Seil
Romain
Orthopédie
03.2014
Alformec
83 journée d'atelier en Médecine
générale
GEFERS
FemmesLuxembourgeoise
et cancer
Société
de
Cardiologie
Neuromodulation
World
Heart Day Société
Luxembourgeoise
de Cardiologie
10. Jahrestagung Deu
Ges für
Neuromodulation
Les
jeunes et le sport : JUST MOVE
American Thoracic
Society
Education
& Research
Day
Post-ESMO Meeting
MIT-A&I 2014
Dtscher Anästhesiekongress
Poumon
Les jeunes &etResearch
le sport :Day
JUST MOVE
Education
Française
d'Arthroscopie
10.
Jahrestagung
Deu Ges für
Bad Oeynshausen (D)
Luxembourg
Bad Oeynshausen (D)
Arrêt cardiaque
Luxembourg
Liège(F)
(B)
Paris
Abstract
: Shwachmann-Diamond
How
should
I treat? (chairman andSyndrome
take homepresenting
message) as early ichthyosis and later
Göteborg (Suède)
Barcelona
(Espagne)
PROOF-registry:
a prospective observational
to describe
disease course and outcomes
Debates
on cardiovascularimaging
in patientsregistry
with coronary
arterythe
disease
of idiopathic
pulmonary
fibrosis
(chairman
abstract
session)
patients in a real-world clinical setting
PROOF-registry: a prospective observational registry to describe the disease course and outcomes
Abstract
reviewer
of idiopathic
pulmonary fibrosis
patientscase
in a real-world
Clinical
discussion clinical setting
Bruxelles (B)
San Diego (USA)
Luxembourg
Namur (B)
Erlangen (D)
Nivelles (B)
Leipzig (D)
Progrès dans la connaissance des modifications génétiques induites par le tabac
PROOF-registry:
a prospective
observational
registry
to describe
the disease
outcomes
Granzyme
B degradation
by autophagy
decreases
tumor
cell susceptibility
to course
naturaland
killer-mediated
of idiopathic
pulmonary fibrosis
lysis
under hypoxia
patients in a real-world clinical setting
Medizinische Innovationen und Technik in Anästhesiologie und Intensivmedizin
Qualität durch Wissenschaft
Luxembourg
Luxembourg
Luxembourg
Cardiopathies
congénitales
et sport :
Quelles
sont les limites ?
Chaque
cas d'asphyxie
est une
occasion
d'apprendre,
études d'évitabilité de l'asphyxie sèvère,
expérience
suédoise
Large animal
models for pediatric ACL reconstruction
Bad Oeynshausen (D)
Luxembourg
Neuromodulation
Neuromodulation
Congrès
annuel
de la Société
for
Ster and
Functional
Neurosurgery
5th course for advanced surgery of
Epileptologie
the knee
Tag
der Epilepsie
the knee
Bad Oeynshausen (D)
Luxembourg
Conception of a three-dimensional kinematics model of the knee joint, based on rigid
body method,
constitutive
lawsinof
ligaments
and validation
with cadaveric
kinematics
Poster
: Postoperative
imaging
Deep
Brain Stimulation
: a controversial
issue
study with navigation system; and application to the analysis of ligament ruptures
(free paper)
Changes in onset times of muscular activity during a side hop task (free paper)
Bad Oeynshausen (D)
Luxembourg
Pediatric
ACL injuries:
what have
we learned over the last decade?
in
the treatment
for trigeminal
pain
Washington (USA)
Luxembourg
Symposium on meniscal repair
Bonn (D)
Val d'Isère (F)
Meniscal tears in children and young athletes
Dresden (D)
Val d'Isère (F)
Zürich (CH)
Management of ACL injuries in the skeletally immature patient
Jahrestagung
GNPI
surgery of
5th course for advanced
the kneesociety of pediatric
Belgian
neurology
the knee
49th
Canadian
for advancedSciences
surgery of
5th course Neurological
Federation
the knee
Bonn
(D) (F)
Val d'Isère
Liège (B)
50.
Jahrestagung
der surgery of
for advanced
5th course
Oesterreichischen
the knee
Biennal
meeting
of the American Soc
Française
d'Arthroscopie
8e journée de chirurgie du genou du
GEFERS
SEG
NLS
formation
ERC
8e journée
de chirurgie
du genou du
Wien
(A) (F)
Val d'Isère
Gap balancing in TKA: dealing with the sagittal plane (recurvatum, flexion
contracture, patellar height).
Ungewöhnlicher
VerlaufSkin
eines
malignen
Meningeoms
after previous surgery:
incisions
– approaches
Luxembourg
Washington (USA)
Bruxelles (B)
Luxembourg
Actualités sur les réparations méniscales
Bordeaux
(F)
Bruxelles (B)
Introduction
et direction
Les lésions méniscosynoviales
postérieures
Bruxelles (B)
Luxembourg
Le ménisque pédiatrique
Milano (I)
Luxembourg
Patellofemoral pathology in adolescent football players
Osnabrück (D)
Nachbehandlung nach VKB Rupturen
Neuromodulation
Française
d'Arthroscopie
10.
Jahrestagung
Deu Ges für
Neuromodulation
SEG
Congrès
National de la Société
Française
8e journéede
deTabacologie
chirurgie du genou du
SEG
Luxembourgeoise
de Cardiologie
International
conference
on football
medicine
Cardiologie
7. Osnabrücker Symposium
Bad Oeynshausen (D)
Val d'Isère (F)
Banff (Canada)
Val d'Isère (F)
Osteochondritis dissecans. Definition, etiology, epidemiology
hypoglycemia
with dermal
andknee
epidermal
lipid droplet deposition
Associated neurolysis
in total
arthroplasty
99
the knee
Seil
Romain
Orthopédie
presentations
at congresses
Seil
Romain
Orthopédie
100
contracture, patellar height).
02.2014
the knee
Val d'Isère (F)
after previous surgery: Skin incisions – approaches
04-06.12.2016
Luxembourg
Seil
Surname
Romain
Name
Service
Orthopédie
Date
03.2014
SEG
Bruxelles (B)
City
Seil
Allard
Romain
Serge
Orthopédie
Pédiatrie
03.2014
18.10.2014
SEG
Bruxelles (B)
Luxembourg
Les lésions méniscosynoviales postérieures
Azagra
Seil
Juan
S
Romain
Chirurgie
Orthopédie
29.04.2014
03.2014
Impact
of digital
multimedia system communication (OR1) in surgical practice and education
Le ménisque
pédiatrique
Juan S
Romain
Jose
Chirurgie
Orthopédie
Médecine
physique
01-03.10.2014
03.2014
29-30.03.2014
Education
Research
8e journée &de
chirurgieDay
du genou du
SEG Congrès Français de Chirurgie
116e
Luxembourg
Bruxelles (B)
Azagra
Seil
Azzolin
Paris (F)
Milano (I)
Weiskirchen
(D)
Patellofemoral
in adolescent football players
Prise
en chargepathology
des lombalgies
Seil
Bache
Romain
Manon
Orthopédie
Néonatologie
03.2014
16.05.2014
Osnabrück (D)
Luxembourg
Nachbehandlung
nach VKB
Rupturen
Ethique
de l'organisation,
éthique
du management
Beissel
Seil
Jean
Romain
Cardiologie
Orthopédie
22.03.2014
03.2014
Luxembourg
Sevilla (E)
ESSKA multiligament knee injury symposium: Complications and Outcomes
Beissel
Jean
Cardiologie
27.09.2014
Luxembourg
Arrêt cardiaque
Beissel
Seil
Jean
Romain
Cardiologie
Orthopédie
18.10.2014
05.2014
Les
le sport : JUST MOVE
ESSKA et
congress
16th jeunes
Luxembourg
Amsterdam (NL)
Projet
scolaire :
Formation
Réagis etACL
installation
Complication
potential
in pediatric
patients défibrillateurs semi automatisé
Beissel
Seil
Jean
Romain
Cardiologie
Orthopédie
20
- 23.05.2014
05.2014
Paris
(F)
Amsterdam
(NL)
How
should
I treat?
(chairman
take home message)
Return
to Sports
after
Meniscusand
Surgery
Seil
Beissel
Seil
Romain
Jean
Romain
Orthopédie
Cardiologie
Orthopédie
05.2014
30.08 - 03.09.2014
05.2014
EuroPCR,
session Bosnia,
congress
16th ESSKAJoint
Romania
and Luxembourg
th
16 ESSKA congress
ESC Congress
Japan Orthopaedic Association
Amsterdam (NL)
Barcelona (Espagne)
Kobe (JP)
Seil
Beissel
Romain
Jean
Orthopédie
Cardiologie
06.2014
30.08
- 03.09.2014
Berlin (D) (Espagne)
Barcelona
Das kindliche Kreuzband
im Sport
Cardiopulmonary
resuscitation
: new insights (chairman abstract session)
Beissel
Seil
Berchem
Seil
Jean
Romain
Guy
Romain
Cardiologie
Orthopédie
Onco-Hémato
Orthopédie
30.08 - 03.09.2014
06.2014
25-29.06.2014
06.2014
Barcelona (Espagne)
London (UK)
Barcelona (Espagne)
London (UK)
Abstract reviewer
ESSKA Symposium: Advanced meniscal repair
Instructional course lecture: Meniscal repair
Seil
Berchem
Romain
Guy
Orthopédie
Onco-Hémato
07.2014
24.04.2014
Vail (Co, USA)
Bruxelles
(B)
Preserve the meniscus at all costs: advanced indications for repair
Berchem
Seil
Guy
Romain
Onco-Hémato
Orthopédie
29.04.2014
07.2014
Luxembourg
Vail (Co, USA)
Osteotomies
for Chronic Multiple Ligament Injuries
lysis
under hypoxia
Berchem
Seil
Berchem
Guy
Romain
Guy
Onco-Hémato
Orthopédie
Onco-Hémato
11.10.2015
07.2014
03.04.2014
Namur (B)
Vail (Co, USA)
Nivelles (B)
Trochleoplasty for trochlear dysplasia
Seil
Berglund
Romain
Sophie
Orthopédie
Gyn-Obstétrique
07.2014
29.04.2014
4. Berliner
Expertenmeeting
ESC
Congress
Sportmedizin
ESC
Congress
15th EFORT congress
16th
World Congress on
15th EFORT congress
Gastrointestinal
Cancer
Vail International
Jury
Prix Galien Complex Knee
Symposium
Vail International Complex Knee
Symposium
Post-ESMO Meeting
Chimiothérapie
Glioblastome et
Symposium
Poumon
Education
Symposium& Research Day
New ways to evaluate static rotational knee laxity
Management
of pediatric
ACL injuries
(chairman
abstract
session)
Seil
Bernard
Romain
Florian
Orthopédie
Neurochirurgie
07.2014
11.2014
Vail (Co, USA)
Bad Oeynshausen (D)
Seil
Bernard
Romain
Florian
Orthopédie
Neurochirurgie
08.2014
11.2014
10.
Symposium
Neuromodulation
Frankfurter Spätsommersymposium,
10.
Berufsgenossenschaftliche
Neuromodulation
Unfallklinik
Live Surgery: complex meniscal repair
Live Surgery: Use of fluoroscopy for cruciate/collateral/MPFL Diagnosis and Anatomic Placement
Berlin (D)
Bad Oeynshausen (D)
Meniskus und Kreuzband - primärer und sekundärer Stabilisator: wer hilft wem aus biomechanischer
Poster
Sicht? : Postoperative imaging in Deep Brain Stimulation : a controversial issue
Bernard
Seil
Florian
Romain
Neurochirurgie
Orthopédie
11.2014
09.2014
10.
Deu Ges für
anniversary congress
50thJahrestagung
Neuromodulation
orthopaedic university clinic Base
Bad
(D)
BaselOeynshausen
(CH)
Poster
: Interactive
hierarchical
segmentation
for deep
structure
identifitcation
Improving
quality of
life and performance:
Present
andbrain
future
of orthopaedic
sports medicine.
Orthopaedics: today and future
Berthold
Seil
Christophe
Romain
Neurochirurgie
Orthopédie
11.2014
09.2014
Romain
Christophe
Orthopédie
Neurochirurgie
09.2014
Innsbruck (A)
Washington (USA)
Poster
: Pulsed
high frequency stimulation or thermocoagulation
Die kindliche
Kreuzbandverletzung
International session ACL+…: Pediatric ACL injuries
Seil
Beyenburg
Romain
Stefan
Orthopédie
Neurologie
10.2014
14-17.05.2014
Albufeira (P)
Bonn (D)
Pediatric ACL injuries
Seil
Beyenburg
Romain
Stefan
Orthopédie
Neurologie
11.2014
02-03.05.2014
10.
5. Arthromedicum
Neuromodulation
Annual meeting of the germanBiennal
of thesociety
American Soc
speakingmeeting
arthroscopy
Annual congress of the Portuguese
Jahrestagung
Dt Gesellschaft
für
orthopaedic association
(SPOT)
Epileptologie
Osteotomy-a masterclass
Kleinwachauer
Epilepsiesymposium
programme
Bad
Oeynshausen
(D)
Chiemsee
(D)
Seil
Berthold
Basingstoke (UK)
Dresden (D)
High tibial osteotomy versus unicondylar knee arthroplasties
Beyenburg
Seil
Stefan
Romain
Neurologie
Orthopédie
01-03.10.2014
11.2014
Die
Darstellungwhat
der Epilepsie
in den
Medien
Rehabilitation:
can a patient
expect
to do following an osteotomy ?
Lutz
Romain
Armand
Néonatologie
Orthopédie
Pédiatrie
27-28.05.2014
11.2014
21.11.2014
Tag
der Epilepsie
Osteotomy-a
masterclass
programme GNPI
Jahrestagung
Zürich
(CH) (UK)
Basingstoke
Bindl
Seil
Biver
Bonn (D)
München
Liège
(B) (D)
Regensburg (D)
Meniskusverletzungen:
von der Resektion
zurpresenting
Transplantation
Abstract
: Shwachmann-Diamond
Syndrome
as early ichthyosis and later
hypoglycemia
with dermal
and epidermal
lipid
droplet deposition
Cartilage regeneration
in patients
with open
physes
Banff (Canada)
Seil
Romain
Orthopédie
11.2014
Boecher-Schwarz
Hans
Neurochirurgie
03-06.06.2014
Seil
Romain
Orthopédie
02.2014
Boecher-Schwarz
Seil
Hans
Romain
Neurochirurgie
Orthopédie
09-10.10.2014
04-06.12.2016
Boeker
Sertznig
Dagmar
Claude
Douleur
Soins Intensifs
07-10.09.2014
Boisanté
Sow
Catherine
Rouguiatou
Douleur
Cardiologie
16.05.2014
18.10.2014
Bottu
Stammet
Charpentier
Jean
Pascal
Catherine
Néonatologie
Soins Intensifs
Pneumologie
02-05.07.2014
07-10.09.2014
23-25.10.2014
Stammet
Charpentier
Pascal
Catherine
Soins
Intensifs
Pneumologie
10.12.2014
27.09.2014
Stammet
Dadoun
Standhardt
Pascal
Frédéric
Harald
Soins
Intensifs
Endocrinologie
Neurochirurgie
29.04.2014
22.03.2015
09-10.10.2014
International conference
on football
Rhumatologie
et Orthopédie,
medicine
Alformec
7. Osnabrücker Symposium
GEFERS
Orthopädie – Unfallchirurgie
Société
Luxembourgeoise de
2nd combined Annual congress of the
Cardiologie
Spanish Association
World
Heartof
Day
for
Surgery
theSociété
Knee and
Arthroscopy
Alwin –Jäger-Kurs
Belgian
society of pediatric
neurology
International congress for translation
in regenerative
medicine:
knee joint
49th
Annual Congress
of the
regeneration
Canadian
Neurological Sciences
Federation
12. Arthroskopie – und
Diagnostikkurs
50.
Jahrestagung der
Vail (Co, USA)
Luxembourg
Actualités sur les réparations méniscales
Wolkenstein (I)
Osteotomien am Kniegelenk – eine Standortbestimmung
Wien (A)
Luxembourg
Individualised knee laxity profiles: combined measurements of anterior and rotational laxity
measurements.
Biennal
meeting of
the American Soc
5th International
Hypothermia
for
Symposium
Washington
(USA)
Edinbourgh (Ecosse)
Epidural
pulsed radiofrequenvy
for opain
treatment-a
retrospective
study arrest
Poster : Bispectral
index as early(Eprf)
predictor
of neurological
outcome
after cardiac
GEFERS
(HTAP)
NLS
formation ERC
Luxembourg
Luxembourg
Ethique
de l'organisation,
du management
Cardiopathies
associées à éthique
des shunts,
bilan et conduite à tenir?
Bordeaux (F)
Edinbourgh (Ecosse)
Clermont-Ferrand
(F)
Poster : Bispectral
as early
predictor
of neurological
Présidence
sessionindex
: sevrage
et prises
en charge
intégrées outcome after cardiac arrest
2nd
personalized
medicine
World
Heart Day Société
consortium
meeting
Luxembourgeoise
deLCSB
Cardiologie
Esch/Alzette
Luxembourg
Long
non coding
RNAs
to predict
outcome
after cardiac arrest
E-cigarette
: Qu'en
penser
en septembre
2014?
Education
& Research Day de
Société Luxembourgeoise
Cardiologie
50.
Jahrestagung der
Luxembourg
Luxembourg
Wien (A)
Targeted
temperature
management
at 33C° vs 36C° after cardiac arrest
Regards croisés
et questions
ouvertes
Oesterreichischen
Gesellsch.
Für Neurochirurgie
5th
International
Congrès
NationalHypothermia
de la Société
Symposium
Française
de Tabacologie
101
regeneration
Seil
Romain
Orthopédie
presentations
at congresses
Seil
Romain
Orthopédie
102
02.2014
12. Arthroskopie – und
Diagnostikkurs
Wolkenstein (I)
Osteotomien am Kniegelenk – eine Standortbestimmung
04-06.12.2016
Luxembourg
Individualised knee laxity profiles: combined measurements of anterior and rotational laxity
measurements.
Sertznig
Surname
Claude
Name
Service
Soins Intensifs
Date
07-10.09.2014
5th International Hypothermia
Symposium
Edinbourgh (Ecosse)
City
Sow
Allard
Rouguiatou
Serge
Cardiologie
Pédiatrie
18.10.2014
18.10.2014
(HTAP)
Luxembourg
Luxembourg
Cardiopathies associées à des shunts, bilan et conduite à tenir?
Azagra
Stammet
Juan
PascalS
Chirurgie
Soins Intensifs
29.04.2014
07-10.09.2014
Impact
digital multimedia
system
communication
(OR1) outcome
in surgical
practice
andarrest
education
Poster :of
Bispectral
index as early
predictor
of neurological
after
cardiac
Juan S
Pascal
Jose
Chirurgie
Soins Intensifs
Médecine
physique
01-03.10.2014
10.12.2014
29-30.03.2014
Education
& Research
Day
5th International
Hypothermia
Symposium
116e
Congrès Français de Chirurgie
Luxembourg
Edinbourgh (Ecosse)
Azagra
Stammet
Azzolin
Paris (F)
Esch/Alzette(D)
Weiskirchen
Long en
noncharge
codingdes
RNAs
to predict outcome after cardiac arrest
Prise
lombalgies
Stammet
Bache
Standhardt
Beissel
Pascal
Manon
Harald
Jean
Soins Intensifs
Néonatologie
Neurochirurgie
Cardiologie
29.04.2014
16.05.2014
09-10.10.2014
22.03.2014
Luxembourg
Luxembourg
Wien (A)
Luxembourg
Targetedde
temperature
management
33C° vs 36C° after cardiac arrest
Ethique
l'organisation,
éthique duatmanagement
Ungewöhnlicher
To
pace or not toVerlauf
pace eines malignen Meningeoms
Beissel
Staub
Jean
Thérèse
Cardiologie
Maladies Infectieuses
27.09.2014
23-24.10.2015
Luxembourg
Berlin (D)
Beissel
Stein
Beissel
Stein
Jean
Romain
Jean
Romain
Cardiologie
Médecine pénitentiaire
Cardiologie
Médecine pénitentiaire
18.10.2014
02-06.07.2014
20 - 23.05.2014
19.11.2014
Arrêt cardiaque
High recurrence rate of hepatitis C infection after treatment in prison in inmates
in Luxembourg
Flexibility in General Practice, definition and concepts
Optimiser la prise en charge de l'insuffisant cardiaque à domicile
Thünenkötter
Beissel
Thomas
Jean
Médecine du Sport
Cardiologie
23.05.2014
30.08
- 03.09.2014
Urhausen
Beissel
Urhausen
Beissel
Axel
Jean
Axel
Jean
Médecine du Sport
Cardiologie
Médecine du Sport
Cardiologie
09.05.2014
30.08
- 03.09.2014
13.12.2014
30.08
- 03.09.2014
Berchem
Guy
Onco-Hémato
25-29.06.2014
Urhausen
Berchem
Urhausen
Berchem
Axel
Guy
Axel
Guy
Médecine du Sport
Onco-Hémato
Médecine du Sport
Onco-Hémato
02.07.2014
24.04.2014
04-06.12.2016
29.04.2014
Urhausen
Berchem
Urhausen
Berchem
Urhausen
Axel
Guy
Axel
Guy
Axel
Médecine du Sport
Onco-Hémato
Médecine du Sport
Onco-Hémato
Médecine du Sport
18.10.2014
11.10.2015
10.05.2014
03.04.2014
09.04.2014
Van Giffen
Berglund
Nicolien
Sophie
Orthopédie
Gyn-Obstétrique
04-06.12.2016
29.04.2014
Vervier
Bernard
Vervier
Jean-François
Florian
Jean-François
Pédopsychiatrie
Neurochirurgie
Pédopsychiatrie
07-10.05.2014
11.2014
26-27.02.2014
Bernard
Vervier
Florian
Jean-François
Neurochirurgie
Pédopsychiatrie
11.2014
20.06.2014
Bernard
Florian
Neurochirurgie
11.2014
Vervier
Berthold
Jean-François
Christophe
Pédopsychiatrie
Neurochirurgie
17.10.2014
11.2014
Berthold
Wagner
Christophe
Daniel
Neurochirurgie
Cardiologie
22.03.2016
Beyenburg
Wagner
Stefan
Daniel
Neurologie
Cardiologie
14-17.05.2014
29.04.2014
Werer
Beyenburg
Christophe
Stefan
Soins Intensifs
Neurologie
07-10.09.2014
02-03.05.2014
Beyenburg
Wirth
Bindl
Wirth
Biver
Stefan
Claudine
Lutz
Claudine
Armand
Neurologie
Rhumatologie
Néonatologie
Rhumatologie
Pédiatrie
01-03.10.2014
18.10.2014
27-28.05.2014
29-30.03.2014
21.11.2014
Wirtz
Boecher-Schwarz
Gil
Hans
Pneumologie
Neurochirurgie
18.10.2014
03-06.06.2014
Boecher-Schwarz
Hans
Neurochirurgie
09-10.10.2014
Boeker
Dagmar
Douleur
Boisanté
Catherine
Douleur
Bottu
Jean
Néonatologie
Charpentier
Catherine
Charpentier
Dadoun
2nd personalized
medicine
Rhumatologie
et Orthopédie,
consortium meeting LCSB
Alformec
GEFERS
50. Jahrestagung
der
Société
Luxembourgeoise
de
Oesterreichischen
Cardiologie
First European conference
on
Luxembourgeoise
de Cardiologie
Hepatitis Cand drug use
Congrès WONCA Europe (abstract)
Semaine médicale
de Lorraine
Romania
and Luxembourg
Journée
thématique autour de
ESC
Congress
l'obésité
Luxembourg
Lisbonne (P)
Paris (F)
Nancy (F)
Luxembourg
Barcelona
(Espagne)
Europrevent
Congress
ESC
Congress
Jahreskongress
ESC Congress der Deutschen
Gesellsch. Für Sportmedizin und
16th
World Congress on
Prävention
World Congress of Cycling Science
Jury Prix Galien
Education
& Research Day
Amsterdam
(NL)
Barcelona
(Espagne)
Frankfurt
(D)
Barcelona (Espagne)
Post-ESMO Meeting
Workshop Alformec
22e Séminaire Médecine du Sport
Poumon
Congrès annuel
de la Société
Education
& Research
Day
Luxembourg
Namur (B)
Mondorf-les-Bains
Nivelles (B)
Val d'Isère (F)
Congrès
AEPEA Deu Ges für
10.
Jahrestagung
Neuromodulation
8ème journées de Prévention du
suicide
Bruxelles
(B)
Bad
Oeynshausen
(D)
Luxembourg
Poster : Bispectral index as early predictor of neurological outcome after cardiac arrest
Die Bedeutung
der körperlichen Aktivität
und der
zur Vorbeuge
Debates
on cardiovascularimaging
in patients
withErnährung
coronary artery
disease und Behandlung des
Übergewichts
(chairman
abstract session)
The heart-lung interaction
in preventive
cardiology
(moderation)
Cardiopulmonary
resuscitation
: new insights
(chairman
abstract session)
Gesundheit
im Leistungssport aus internistischer Sicht.
Abstract
reviewer
Barcelona (Espagne)
Leeds (GB)
Bruxelles (B)
Luxembourg
Luxembourg
Exercice physiology session (moderation)
Luxembourg
Luxembourg
Clinical and scientific perspective for the future of sports medicine in Luxemburg
lysis under hypoxia
Examen médico-sportif du jeune athlète
Médecine du Sport - du diagnostic au traitement.
Paramètres sanguins dans le suivi de sportif de compétition
Surgical cas
portals
in ankleest
arthroscopy
Chaque
d'asphyxie
une occasion d'apprendre, études d'évitabilité de l'asphyxie sèvère,
Présidence
sessions
Poster
: Modelling
Trauma, deuil et exil
Bad Oeynshausen (D)
Luxembourg
Prises en charge hospitalières et transculturelles des jeunes migrants et leurs familles
Bad Oeynshausen (D)
Journée
du Réseau
nord
européen
10.
Jahrestagung
Deu
Ges– für
francophone de Pédopsychiatrie de
Neuromodulation
Liaison,
Société
de
for
Ster Luxembourgeoise
and Functional Neurosurgery
Cardiologie
Epileptologie
Nancy
(F)
Bad
Oeynshausen
(D)
Annonce
du diagnostic
d’autisme
dans uneor
pratique
pluridisciplinaire et
Poster
: Pulsed
high frequency
stimulation
thermocoagulation
multiculturelle
aufor
Luxembourg,
in
the treatment
trigeminal pain
Washington (USA)
Luxembourg
Angor stable, une espèce en voie de disparition
Bonn (D)
Luxembourg
Circulating microRNAs after cardiac arrest
5th International
Hypothermia
Kleinwachauer
Epilepsiesymposium
Symposium
Tag der Epilepsie
Journée de Rhumatologie, Alformec
Jahrestagung GNPI
Belgian
society of pediatric
Alformec
neurology
49th
(HTAP)
Federation
Edinbourgh
Dresden
(D) (Ecosse)
Poster : Bispectral index as early predictor of neurological outcome after cardiac arrest
Zürich (CH)
Luxembourg
Bonn (D)
Weiskirchen (D)
Liège (B)
Luxembourg
Banff (Canada)
Rhumatologie
Rhumatologie
Diagnostic et classification de l'hypertension artérielle pulmonaire: une approche pluridisciplnaire
Oesterreichischen
Wien (A)
Washington (USA)
16.05.2014
GEFERS
Luxembourg
02-05.07.2014
NLS formation ERC
Bordeaux (F)
Pneumologie
23-25.10.2014
Catherine
Pneumologie
27.09.2014
Luxembourg
Frédéric
Endocrinologie
22.03.2015
Cardiologie
Luxembourg
Neuromodulation
Journée d’étude du Ministère de
l’éducation
nationale,
10.
Jahrestagung
Deu Ges für
de l’Enfance et de la jeunesse
Neuromodulation
103
Centre Hospitalier de Luxembourg
4, rue Ernest Barblé L-1210 Luxembourg
Tél : +352 44 11 11 Fax : +352 45 87 62 www.chl.lu

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A joindre immédiatement à cette déclaration

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Porte Du Luxembourg Apartments Arlon Belgium

Visiting LuxSpace v5

mediawatch - Luxembourg for Finance

LUXEMBOURGISH REAL ESTATE TAXATION 1