pole hospitalier neurosciences cliniques - Faculté de Médecine
Transcription
pole hospitalier neurosciences cliniques - Faculté de Médecine
POLE HOSPITALIER NEUROSCIENCES CLINIQUES PERSONNELS RATTACHÉS A UNE EQUIPE DE RECHERCHE Azulay Jean Philippe (1,2) Alexandre Eusebio (1) Witjas Tatiana (1) Fluchère Frédérique (2) Emmanuelle Boutin (2) PU-PH PHU PH PH CCA 1/ Institut des Neurosciences de la Timone CNRS-UMR7289 et 2/ Laboratoire Neuroscience et Cognition (LNC - UMR 7291) Université d'Aix-Marseille SERVICES HOSPITALIERS INTITULÉ : Service de Neurologie et Pathologie du Mouvement RESPONSABLE : Pr Azulay DISCIPLINE : Neurologie PUBLICATIONS ANNÉE 2014 1: Caudron S, Guerraz M, Eusebio A, Gros JP, Azulay JP, Vaugoyeau M. Evaluation of a visual biofeedback on the postural control in Parkinson's disease. Neurophysiol Clin. 2014 Jan;44(1):77-86. doi: 10.1016/j.neucli.2013.10.134. 2: Azulay JP. [The Review of Neurology exists since 1883 and is therefore 130 years old, a more than respectable age that should not represent a brake to evolution and change]. Rev Neurol (Paris). 2014 Jan;170(1 3: Désaméricq G, Dolbeau G, Verny C, Charles P, Durr A, Youssov K, Simonin C, Azulay JP, Tranchant C, Goizet C, Damier P, Broussolle E, Demonet JF, Morgado G, Cleret de Langavant L, Macquin-Mavier I, Bachoud-Lévi AC, Maison P. Effectiveness of anti-psychotics and related drugs in the Huntington French-speaking groupcohort. PLoS One. 2014 Jan 15;9(1): 4: Ory-Magne F, Corvol JC, Azulay JP, Bonnet AM, Brefel-Courbon C, Damier P, Dellapina E, Destée A, Durif F, Galitzky M, Lebouvier T, Meissner W, Thalamas C, Tison F, Salis A, Sommet A, Viallet F, Vidailhet M, Rascol O; NS-Park CIC Network. Withdrawing amantadine in dyskinetic patients with Parkinson disease: the AMANDYSK trial. Neurology. 2014 Jan 28;82(4):300-7. 5: Fluchere F, Witjas T, Eusebio A, Bruder N, Giorgi R, Leveque M, Peragut JC, Azulay JP, Regis J. Controlled general anaesthesia for subthalamic nucleus stimulation in Parkinson's disease. J Neurol Neurosurg Psychiatry. 2014 Oct;85(10):1167-73. 6: Devos D, Moreau C, Maltête D, Lefaucheur R, Kreisler A, Eusebio A, Defer G, Ouk T, Azulay JP, Krystkowiak P, Witjas T, Delliaux M, Destée A, Duhamel A, Bordet R, Defebvre L, Dujardin K. Rivastigmine in apathetic but dementia and depression-free patients with Parkinson's disease: a double-blind, placebo-controlled, randomised clinical trial. J Neurol Neurosurg Psychiatry. 2014 Jun;85(6):668-74. Pôle hospitalier. Neurosciences Cliniques Mis à jour : janvier 2016 1/31 POLE HOSPITALIER NEUROSCIENCES CLINIQUES PERSONNELS RATTACHÉS A UNE EQUIPE DE RECHERCHE NOMS FONCTIONS PELLETIER Jean (MD,PhD) AUDOIN Bertrand (MD,PhD) RICO Audrey (MD,PhD) KAPHAN Elsa (MD) ROBINET Emmanuelle (MD) MOLL Natalia (MD,PhD) CRESPY Lydie (MD) DOCHE Emilie (MD) RANJEVA Marie Pierre (PhD) PH PUPH PUPH PH PH PH Associé CCA CCA Ingénieur de Recherche CRMBM/CEMEREM UMR-CNRS7339 Faculté de Médecine et CHU Timone Aix-Marseille Université SERVICES HOSPITALIERS INTITULÉ : Service de Neurologie et Urgences NeuroVasculaires RESPONSABLE : Pr. Jean Pelletier DISCIPLINE : Neurologie THESES DE DOCTORAT ANNÉE 2014 Anthony Faivre - Etude de la réorganisation de la connectivité cérébrale au repos dans la sclérose en plaques. Doctorat en Sciences (Université de la Méditerranée). Direction B. Audoin et JP Ranjeva. Juillet 2014. CONTRATS ANNÉE 2014 1. 2. 3. 4. Pelletier J (Coordonateur). A study of axonal degeneration using cerebral sodium (23Na) Magnetic Resonance Imaging to differentiate benign (BMS) and non benign Multiple Sclerosis NBMS) ARSEP ‘23Na MRI in benign MS’ (PI J Pelletier). AO ARSEP 2014. Pelletier J (Co-investigateur). EMISEP : Atteinte IRM médullaire précoce et handicap physique tardif chez les patients atteints de SEP rémittente (PI G Edan). PHRC National (2013-2015). Pelletier J (Coordonateur). A longitudinal study of axonal degeneration in patients with Multiple Sclerosis using cerebral sodium (23Na) Magnetic Resonance Imaging (PI J Pelletier). NOVARTIS 2013-2015. Pelletier J. (Co-investigateur). TRAP-Myéline : Etude multicentrique, contrôlée, prospective et non randomisée visant à analyser le test TRAP-myéline comme outil diagnostique dans la Sclérose en plaques (PI DA Laplaud) PHRC National (2011-2014). PUBLICATIONS ANNÉE 2014 1. Calabresi PA, Kieseier BC, Arnold DL, Balcer LJ, Boyko A, Pelletier J, Liu S, Zhu Y, Seddighzadeh A, Hung S, Deykin A; ADVANCE Study Investigators. Pegylated interferon β1a for relapsing-remitting multiple sclerosis (ADVANCE): a randomised, phase 3, doubleblind study. Lancet Neurol. 2014;13(7):657-65. 2. Okuda DT, Siva A, Kantarci O, Inglese M, Katz I, Tutuncu M, Keegan BM, Donlon S, Hua le H, Vidal-Jordana A, Montalban X, Rovira A, Tintoré M, Amato MP, Brochet B, de Seze J, Brassat D, Vermersch P, De Stefano N, Sormani MP, Pelletier D, Lebrun C; Radiologically Isolated Syndrome Consortium (RISC); Club Francophone de la Sclérose en Plaques Pôle hospitalier. Neurosciences Cliniques Mis à jour : janvier 2016 2/31 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. (CFSEP) (J Pelletier, mambre). Radiologically isolated syndrome: 5-year risk for an initial clinical event. PLoS One. 2014 Mar 5;9(3):e90509. Kaphan E, Barbeau E, Royère ML, Guedj E, Pelletier J, Ali Chérif A. Ganser-like Syndrome After Loss of Psychic Self-activation Syndrome: Psychogenic or Organic? Arch Clin Neuropsychol. 2014; 29(7):715-23 Genetic pleiotropy between multiple sclerosis and schizophrenia but not bipolar disorder: differential involvement of immune-related gene loci. The International Multiple Sclerosis Genetics Consortium (IMSGC, J Pelletier, member). The Psychiatric Genomics Consortium (PGC) Bipolar Disorder and Schizophrenia Work Groups. Mol Psychiatry. 2014 (In Press, Jan 28. doi: 10.1038/mp.2013.195). Khatri BO, Pelletier J, Kappos L, Hartung HP, Comi G, Barkhof F, vonRosenstiel P, Meng X, Grinspan A, Hashmonay R, Cohen JA, on behalf of the TRANSFORMS Study Group. Effect of prior treatment status and reasons for discontinuation on the efficacy and safety of fingolimod vs. interferon β-1a intramuscular: Subgroup analyses of the Trial Assessing Injectable Interferon vs. Fingolimod Oral in Relapsing–Remitting Multiple Sclerosis (TRANSFORMS). Multiple Sclerosis and Related Disorders. In Press. [Epub ahead of print] Michel P, Baumstarck K, Boyer L, Fernandez O, Flachenecker P, Pelletier J, Loundou A, Ghattas B, Auquier P; on behalf of the MusiQoL Study Group. Defining Quality of Life Levels to Enhance Clinical Interpretation in Multiple Sclerosis: Application of a Novel Clustering Method. Med Care. 2014 (In Press). [Epub ahead of print] Baumstarck K, Boucekine M, Boyer L, Aghababian V, Parola N, Reuter F, Loundou A, Lançon C, Pelletier J, Auquier P. Quantification of relevance of quality of life assessment for patients with cognitive impairment: the suitability indices. BMC Neurol. 2014 Apr 8;14:78. Cohen M, Maillart E, Tourbah A, De Sèze J, Vukusic S, Brassat D, Anne O, Wiertlewski S, Camu W, Courtois S, Ruet A, Debouverie M, Le Page E, Casez O, Heinzlef O, Stankoff B, Bourre B, Castelnovo G, Rico A, Berger E, Camdessanche JP, Defer G, Clavelou P, Al Khedr A, Zephir H, Fromont A, Papeix C, Brochet B, Pelletier J, Lebrun C; for the Club Francophone de la Sclérose en Plaques Investigators. Switching From Natalizumab to Fingolimod in Multiple Sclerosis: A French Prospective Study. JAMA Neurol. 2014;71(4):436-41. Collongues N, Papeix C, Zéphir H, Audoin B, Cotton F, Durand-Dubief F, Vukusic S, Brassat D, Laplaud D, Marignier R; Groupe Nomadmus (J. Pelletier, member). Nosology and etiologies of acute longitudinally extensive transverse myelitis. Rev Neurol (Paris). 2014;170(1):6-12. Grimaldi-Bensouda L, Guillemot D, Godeau B, Bénichou J, Lebrun-Frenay C, Papeix C, Labauge P, Berquin P, Penfornis A, Benhamou PY, Nicolino M, Simon A, Viallard JF, Costedoat-Chalumeau N, Courcoux MF, Pondarré C, Hilliquin P, Chatelus E, Foltz V, Guillaume S, Rossignol M, Abenhaim L; the PGRx-AID Study Group (J. Pelletier, member). Autoimmune disorders and quadrivalent human papillomavirus vaccination of young female subjects. J Intern Med. 2013. J Intern Med. 2014;275(4):398-408. Lagarde S, Lagier JC, Charrel R, Quérat G, Vanhomwegen J, Desprès P, Pelletier J, Kaphan E. Japanese encephalitis in a French traveler to Nepal. J Neurovirol. 2014;20(1):99-102. Filippi M, Rocca MA, Pagani E, De Stefano N, Jeffery D, Kappos L, Montalban X, Boyko AN, Comi G; on behalf of the ALLEGRO Study Group (J. Pelletier, member). Placebo-controlled trial of oral laquinimod in multiple sclerosis: MRI evidence of an effect on brain tissue damage. J Neurol Neurosurg Psychiatry. 2014;85(8):851-8. Outteryck O, Ongagna JC, Brochet B, Rumbach L, Lebrun-Frenay C, Debouverie M, Zéphir H, Ouallet JC, Berger E, Cohen M, Pittion S, Laplaud D, Wiertlewski S, Cabre P, Pelletier J, Rico A, Defer G, Derache N, Camu W, Thouvenot E, Moreau T, Fromont A, Tourbah A, Labauge P, Castelnovo G, Clavelou P, Casez O, Hautecoeur P, Papeix C, Lubetzki C, Fontaine B, Couturier N, Bohossian N, Clanet M, Vermersch P, de Sèze J, Brassat D; BIONAT network, and CFSEP. A prospective observational post-marketing study of natalizumab-treated multiple sclerosis patients: clinical, radiological and biological features and adverse events. The BIONAT cohort. Eur J Neurol. 2014;21(1):40-8. Maarouf A, Audoin B, Konstandin S, Rico A, Soulier E, Reuter F, Le Troter A, Confort-Gouny S, Cozzone PJ, Guye M, Schad LR, Pelletier J, Ranjeva JP, ZaaraouiW. Topography of brain sodium accumulation in progressive multiple sclerosis. MAGMA 2014;27(1):53-62. Pôle hospitalier. Neurosciences Cliniques Mis à jour : janvier 2016 3/31 POLE HOSPITALIER NEUROSCIENCES CLINIQUES PERSONNELS RATTACHÉS A UNE EQUIPE DE RECHERCHE Donnet Anne Inserm/UdA, U1107, Neuro-Dol, Trigeminal Pain and Migraine SERVICES HOSPITALIERS Centre d’Evaluation et de Traitement de la Douleur – Hopital Timone- AP HM PUBLICATIONS ANNÉE 2014 Tuleasca C, Carron R, Resseguier N, Donnet A, Roussel P, Gaudart J, Levivier M, Régis J. Repeat Gamma Knife surgery for recurrent trigeminal neuralgia: long-term outcomes and systematic review. J Neurosurg. 2014 Dec;121 Suppl:210-21. Tuleasca C, Carron R, Resseguier N, Donnet A, Roussel P, Gaudart J, Levivier M, Régis J. Multiple sclerosis-related trigeminal neuralgia: a prospective series of 43 patients treated with gamma knife surgery with more than one year of follow-up. Stereotact Funct Neurosurg. 2014;92(4):203-10 Donnet A, Demarquay G, Ducros A, Geraud G, Giraud P, Guegan-Massardier E, Lucas C, Navez M, Valade D, Lanteri-Minet M; French Headache Society. [French guidelines for diagnosis and treatment of cluster headache (French Headache Society)]. Rev Neurol (Paris). 2014 Nov;170(11):653-70. Tuleasca C, Carron R, Resseguier N, Donnet A, Roussel P, Gaudart J, Levivier M, Régis J. Trigeminal neuralgia related to megadolichobasilar artery compression: a prospective series of twenty-nine patients treated with gamma knife surgery, with more than one year of follow-up. Stereotact Funct Neurosurg. 2014;92(3):170-7. Boyer L, Dousset A, Roussel P, Dossetto N, Cammilleri S, Piano V, Khalfa S, Mundler O, Donnet A, Guedj E. rTMS in fibromyalgia: a randomized trial evaluating QoL and its brain metabolic substrate. Neurology. 2014 Apr 8;82(14):1231-8. Lantéri-Minet M, Demarquay G, Alchaar H, Bonnin J, Cornet P, Douay X, Dousset V, Géraud G, Guillouf V, Navez M, Radat F, Radenne S, Revol A, Valade D, Donnet A. [Management of chronic daily headache in migraine patients: medication overuse headache and chronic migraine. French guidelines (French Headache Society, French Private Neurologists Association, French Pain Society)].Rev Neurol (Paris). 2014 Mar;170(3):162-76. . Beltramone M, Donnet A. Status migrainosus and migraine aura status in a French tertiary-care center: An 11-year retrospective analysis. Cephalalgia. 2014 Feb 6;34(8):633-637. Lanteri-Minet M, Valade D, Geraud G, Lucas C, Donnet A. Revised French guidelines for the diagnosis and management of migraine in adults and children.J Headache Pain. 2014 Jan 8;15:2. Pôle hospitalier. Neurosciences Cliniques Mis à jour : janvier 2016 4/31 Unité UMR INSERM 1106 Institut de Neurosciences des Systèmes Faculté de Médecine Timone http://ins.medecine.univmed.fr PERSONNELS RATTACHÉS A UNE EQUIPE DE RECHERCHE Fabrice Bartolomei, PU-PH, Directeur de la Fédération Hospitalo-Universitaire (FHU) « Epilepsies et Troubles de l’excitabilité Neuronale » (EPINEXT) (http://www.epinext.org/) Martine Gavaret, MCU-PH Aileen McGonigal, PH Patrick Chauvel, PU-PH | co-Director Agnes Trebuchon, MCU-PH Francesca Bonini AHU Isabelle Lambert AHU Marc Rey , MCU PH SERVICES HOSPITALIERS INTITULÉ : Service de Neurophysiologie Clinique, CHU Timone RESPONSABLE : Pr Fabrice Bartolomei DISCIPLINE : Neurologie des Epilepsies , Neurophysiologie Clinique Membre de la Fédération Hospitalo-Universitaire (FHU) « Epilepsies et Troubles de l’excitabilité Neuronale » (EPINEXT) (http://www.epinext.org/) PUBLICATIONS ANNÉES 2013-2015 1: Micoulaud-Franchi JA, McGonigal A, Lopez R, Daudet C, Kotwas I, Bartolomei F. Electroencephalographic neurofeedback: Level of evidence in mental and brain disorders and suggestions for good clinical practice. Neurophysiol Clin. 2015 Nov 6. pii: S0987-7053(15)00151-3. doi: 10.1016/j.neucli.2015.10.077. [Epub ahead of print] PubMed PMID: 26553293. 2: Bartolomei F, Trébuchon A, Bonini F, Lambert I, Gavaret M, Woodman M, Giusiano B, Wendling F, Bénar C. What is the concordance between the seizure onset zone and the irritative zone? A SEEG quantified study. Clin Neurophysiol. 2015 Oct 19. pii: S1388-2457(15)00982-7. doi: 10.1016/j.clinph.2015.10.029. [Epub ahead of print] PubMed PMID: 26520456. 3: Mak-McCully RA, Rosen BQ, Rolland M, Régis J, Bartolomei F, Rey M, Chauvel P, Cash SS, Halgren E. Distribution, Amplitude, Incidence, Co-Occurrence, and Propagation of Human K-Complexes in Focal Transcortical Recordings(1,2,3). eNeuro. 2015 Sep 17;2(4). pii: ENEURO.0028-15.2015. doi: 10.1523/ENEURO.0028-15.2015. eCollection 2015 Jul-Aug. PubMed PMID: 26465003; PubMed Central PMCID: PMC4596022. 4: Guerrini R, Duchowny M, Jayakar P, Krsek P, Kahane P, Tassi L, Melani F, Polster T, Andre VM, Cepeda C, Krueger DA, Cross JH, Spreafico R, Cosottini M, Gotman J, Chassoux F, Ryvlin P, Bartolomei F, Bernasconi A, Stefan H, Miller I, Devaux B, Najm I, Giordano F, Vonck K, Barba C, Blumcke I. Diagnostic methods and treatment options for focal cortical dysplasia. Epilepsia. 2015 Nov;56(11):1669-86. doi: 10.1111/epi.13200. Epub 2015 Oct 5. Review. PubMed PMID: 26434565. 5: Evangelista E, Bénar C, Bonini F, Carron R, Colombet B, Régis J, Bartolomei F. Does the Thalamo-Cortical Synchrony Play a Role in Seizure Termination? Front Neurol. 2015 Sep 1;6:192. doi: 10.3389/fneur.2015.00192. eCollection 2015. PubMed Pôle hospitalier. Neurosciences Cliniques Mis à jour : janvier 2016 5/31 PMID: 26388834; PubMed Central PMCID: PMC4555023. 6: Alexandre V, Mercedes B, Valton L, Maillard L, Bartolomei F, Szurhaj W, Hirsch E, Marchal C, Chassoux F, Petit J, Crespel A, Nica A, Navarro V, Kahane P, De Toffol B, Thomas P, Rosenberg S, Denuelle M, Jonas J, Ryvlin P, Rheims S; REPO2MSE study group. Risk factors of postictal generalized EEG suppression in generalized convulsive seizures. Neurology. 2015 Nov 3;85(18):1598-603. doi: 10.1212/WNL.0000000000001949. Epub 2015 Sep 2. PubMed PMID: 26333799. 7: Garbelli R, de Bock F, Medici V, Rousset MC, Villani F, Boussadia B, Arango-Lievano M, Jeanneteau F, Daneman R, Bartolomei F, Marchi N. PDGFRβ(+) cells in human and experimental neuro-vascular dysplasia and seizures. Neuroscience. 2015 Oct 15;306:18-27. doi: 10.1016/j.neuroscience.2015.07.090. Epub 2015 Aug 15. PubMed PMID: 26283024. 8: Muldoon SF, Villette V, Tressard T, Malvache A, Reichinnek S, Bartolomei F, Cossart R. GABAergic inhibition shapes interictal dynamics in awake epileptic mice. Brain. 2015 Oct;138(Pt 10):2875-90. doi: 10.1093/brain/awv227. Epub 2015 Aug 13. PubMed PMID: 26280596. 9: Badier JM, Bénar CG, Woodman M, Cruto C, Chauvel P, Bartolomei F, Gavaret M. Ictal Magnetic Source Imaging in Presurgical Assessment. Brain Topogr. 2015 Aug 12. [Epub ahead of print] PubMed PMID: 26264375. 10: Ridley BG, Rousseau C, Wirsich J, Le Troter A, Soulier E, Confort-Gouny S, Bartolomei F, Ranjeva JP, Achard S, Guye M. Nodal approach reveals differential impact of lateralized focal epilepsies on hub reorganization. Neuroimage. 2015 Sep;118:39-48. doi: 10.1016/j.neuroimage.2015.05.096. Epub 2015 Jun 10. PubMed PMID: 26070261. 11: Jehi L, Chagin K, Yardi R, Tassi L, Russo GL, Worrell G, Cendes F, Morita M, Bartolomei F, Chauvel P, Najm I, Gonzalez-Martinez J, Bingaman W, Kattan MW. Promise and pitfalls of prognostic models for epilepsy surgery-Authors' reply. Lancet Neurol. 2015 Jul;14(7):684. doi: 10.1016/S1474-4422(15)00102-7. PubMed PMID: 26067118. 12: Bodin C, Aubert S, Daquin G, Carron R, Scavarda D, McGonigal A, Bartolomei F. Responders to vagus nerve stimulation (VNS) in refractory epilepsy have reduced interictal cortical synchronicity on scalp EEG. Epilepsy Res. 2015 Jul;113:98-103. doi: 10.1016/j.eplepsyres.2015.03.018. Epub 2015 Apr 9. PubMed PMID: 25986196. 13: Bonini F, Lambert I, Wendling F, McGonigal A, Bartolomei F. Altered synchrony and loss of consciousness during frontal lobe seizures. Clin Neurophysiol. 2015 Apr 15. pii: S1388-2457(15)00286-2. doi: 10.1016/j.clinph.2015.04.050. [Epub ahead of print] PubMed PMID: 25912335. 14: Becker C, Bouvier E, Ghestem A, Siyoucef S, Claverie D, Camus F, Bartolomei F, Benoliel JJ, Bernard C. Predicting and treating stress-induced vulnerability to epilepsy and depression. Ann Neurol. 2015 Jul;78(1):128-36. doi: 10.1002/ana.24414. Epub 2015 May 25. PubMed PMID: 25869354. 15: Wendling F, Benquet P, Bartolomei F, Jirsa V. Computational models of epileptiform activity. J Neurosci Methods. 2015 Apr 3. pii: S0165-0270(15)00122-3. doi: 10.1016/j.jneumeth.2015.03.027. [Epub ahead of print] Review. PubMed PMID: 25843066. 16: Felician O, Tramoni E, Bartolomei F. Transient epileptic amnesia: Update on a slowly emerging epileptic syndrome. Rev Neurol (Paris). 2015 Mar;171(3):289-97. doi: 10.1016/j.neurol.2014.11.010. Epub 2015 Feb 25. PubMed PMID: 25724712. 17: Guedj E, Bonini F, Gavaret M, Trébuchon A, Aubert S, Boucekine M, Boyer L, Carron R, McGonigal A, Bartolomei F. 18FDG-PET in different subtypes of temporal Pôle hospitalier. Neurosciences Cliniques Mis à jour : janvier 2016 6/31 lobe epilepsy: SEEG validation and predictive value. Epilepsia. 2015 Mar;56(3):414-21. doi: 10.1111/epi.12917. Epub 2015 Feb 23. PubMed PMID: 25708545. 18: Jehi L, Yardi R, Chagin K, Tassi L, Russo GL, Worrell G, Hu W, Cendes F, Morita M, Bartolomei F, Chauvel P, Najm I, Gonzalez-Martinez J, Bingaman W, Kattan MW. Development and validation of nomograms to provide individualised predictions of seizure outcomes after epilepsy surgery: a retrospective analysis. Lancet Neurol. 2015 Mar;14(3):283-90. doi: 10.1016/S1474-4422(14)70325-4. Epub 2015 Jan 29. PubMed PMID: 25638640. 19: Micoulaud-Franchi JA, Barkate G, Trébuchon-Da Fonseca A, Vaugier L, Gavaret M, Bartolomei F, McGonigal A. One step closer to a global tool for rapid screening of major depression in epilepsy: validation of the French NDDI-E. Epilepsy Behav. 2015 Mar;44:11-6. doi: 10.1016/j.yebeh.2014.12.011. Epub 2015 Jan 16. PubMed PMID: 25597527. 20: Arthuis M, Micoulaud-Franchi JA, Bartolomei F, McGonigal A, Guedj E. Resting cortical PET metabolic changes in psychogenic non-epileptic seizures (PNES). J Neurol Neurosurg Psychiatry. 2015 Oct;86(10):1106-12. doi: 10.1136/jnnp-2014-309390. Epub 2014 Dec 2. PubMed PMID: 25466258. 21: Micoulaud-Franchi JA, Kotwas I, Lanteaume L, Berthet C, Bastien M, Vion-Dury J, McGonigal A, Bartolomei F. Skin conductance biofeedback training in adults with drug-resistant temporal lobe epilepsy and stress-triggered seizures: a proof-of-concept study. Epilepsy Behav. 2014 Dec;41:244-50. doi: 10.1016/j.yebeh.2014.10.017. Epub 2014 Nov 5. PubMed PMID: 25461224. 22: Annan M, Bartolomei F, Biberon J, Cottier JP, De Toffol B. Appearance of post ictal psychosis after radiosurgical damage in the temporal lobe. Seizure. 2015 Jan;24:140-2. doi: 10.1016/j.seizure.2014.09.008. Epub 2014 Oct 2. PubMed PMID: 25458102. 23: Proix T, Bartolomei F, Chauvel P, Bernard C, Jirsa VK. Permittivity coupling across brain regions determines seizure recruitment in partial epilepsy. J Neurosci. 2014 Nov 5;34(45):15009-21. doi: 10.1523/JNEUROSCI.1570-14.2014. PubMed PMID: 25378166. 24: McGonigal A, Bartolomei F, Gavaret M, Chauvel P, Régis J. Gamma knife radiosurgery of paracentral epilepsy. Stereotact Funct Neurosurg. 2014;92(6):346-53. doi: 10.1159/000364915. Epub 2014 Oct 28. PubMed PMID: 25358847. 25: Badier JM, Bartolomei F, Chauvel P, Bénar CG, Gavaret M. Magnetic source imaging in posterior cortex epilepsies. Brain Topogr. 2015 Jan;28(1):162-71. doi: 10.1007/s10548-014-0412-4. Epub 2014 Oct 29. PubMed PMID: 25352165. 26: Bartolomei F, Tramoni E, Félician O. In response: transient epileptic amnesia. Epilepsia. 2014 Oct;55(10):1678. doi: 10.1111/epi.12746. PubMed PMID: 25330900. 27: Reuber M, Micoulaud-Franchi JA, Gülich E, Bartolomei F, McGonigal A. [What the patient's history tells us about their nonepileptic seizures]. Neurophysiol Clin. 2014 Oct;44(4):375-88. doi: 10.1016/j.neucli.2013.09.002. Epub 2013 Oct 10. Review. French. PubMed PMID: 25306078. 28: de la Vaissière S, Milh M, Scavarda D, Carron R, Lépine A, Trébuchon A, Gavaret M, Hewett R, Laguitton V, Daquin G, Villeneuve N, Bartolomei F. Cortical involvement in focal epilepsies with epileptic spasms. Epilepsy Res. 2014 Nov;108(9):1572-80. doi: 10.1016/j.eplepsyres.2014.08.008. Epub 2014 Aug 30. PubMed PMID: 25212728. 29: Cuccaro A, Bartolomei F, Cupelli E, Galli E, Giachelia M, Hohaus S. Prognostic factors in hodgkin lymphoma. Mediterr J Hematol Infect Dis. 2014 Jul Pôle hospitalier. Neurosciences Cliniques Mis à jour : janvier 2016 7/31 5;6(1):e2014053. doi: 10.4084/MJHID.2014.053. eCollection 2014. Review. PubMed PMID: 25045461; PubMed Central PMCID: PMC4103502. 30: Koubeissi MZ, Bartolomei F, Beltagy A, Picard F. Electrical stimulation of a small brain area reversibly disrupts consciousness. Epilepsy Behav. 2014 Aug;37:32-5. doi: 10.1016/j.yebeh.2014.05.027. Epub 2014 Jun 24. PubMed PMID: 24967698. 31: Andrzejak RG, David O, Gnatkovsky V, Wendling F, Bartolomei F, Francione S, Kahane P, Schindler K, de Curtis M. Localization of Epileptogenic Zone on Pre-surgical Intracranial EEG Recordings: Toward a Validation of Quantitative Signal Analysis Approaches. Brain Topogr. 2015 Nov;28(6):832-7. doi: 10.1007/s10548-014-0380-8. Epub 2014 Jun 15. PubMed PMID: 24929558. 32: Dubarry AS, Badier JM, Trébuchon-Da Fonseca A, Gavaret M, Carron R, Bartolomei F, Liégeois-Chauvel C, Régis J, Chauvel P, Alario FX, Bénar CG. Simultaneous recording of MEG, EEG and intracerebral EEG during visual stimulation: from feasibility to single-trial analysis. Neuroimage. 2014 Oct 1;99:548-58. doi: 10.1016/j.neuroimage.2014.05.055. Epub 2014 May 23. PubMed PMID: 24862073. 33: Maillard L, Gavaret M, Régis J, Wendling F, Bartolomei F. Fast epileptic discharges associated with ictal negative motor phenomena. Clin Neurophysiol. 2014 Dec;125(12):2344-8. doi: 10.1016/j.clinph.2014.03.023. 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PubMed PMID: 3746641. 198: Bartolomei FJ. Pedal radiographic manifestations of the seronegative spondyloarthritides. Part III: Ankylosing spondylitis. J Am Podiatr Med Assoc. 1986 Jul;76(7):380-5. PubMed PMID: 3723383. 199: Fishman SA, Bartolomei FJ. Digital amputation following trauma-induced gangrene. J Am Podiatr Med Assoc. 1986 Jun;76(6):351-4. Erratum in: J Am Podiatr Med Assoc 1986 Nov;76(11):654. PubMed PMID: 3723377. 200: Bartolomei FJ. Pedal radiographic manifestations of the seronegative spondyloarthritides. Part II: Psoriatic arthritis. J Am Podiatr Med Assoc. 1986 May;76(5):266-74. PubMed PMID: 3712253. 201: Bartolomei FJ. Pedal radiographic manifestations of the seronegative spondyloarthritides. Part I: Reiter's syndrome. J Am Podiatr Med Assoc. 1986 Apr;76(4):189-98. PubMed PMID: 3701622. 202: Bartolomei FJ, Noble RJ, Crist JA. Radiodermatitis. A result of therapeutic irradiation of verrucae. J Am Podiatr Med Assoc. 1986 Mar;76(3):157-60. PubMed PMID: 3958941. 203: Bartolomei FJ, Brandwene SM, McCarthy DJ. Bowen's disease. J Am Podiatr Med Assoc. 1986 Mar;76(3):153-6. PubMed PMID: 3958940. 204: Bartolomei FJ, Brandwene SM, McCarthy DJ. Histopathology of squamous cell carcinoma. J Am Podiatr Med Assoc. 1986 Mar;76(3):146-52. PubMed PMID: 3958939. 205: Bartolomei FJ, Georgeoff RM Jr. Pedal manifestations of Brown-Séquard syndrome. A case report. J Am Podiatr Med Assoc. 1985 Nov;75(11):603-6. PubMed PMID: 4067864. 206: Bernstein RH, Bartolomei FJ, McCarthy DJ. Sinus tarsi syndrome. Anatomical, clinical, and surgical considerations. J Am Podiatr Med Assoc. 1985 Sep;75(9):475-80. PubMed PMID: 3930697. 207: Bartolomei FJ, McCarthy DJ, Gastwirth CM, Peet FJ Jr. Epidermal cyst of the plantar surface. J Am Podiatr Med Assoc. 1985 Apr;75(4):207-10. PubMed PMID: 3989705. 208: Bartolomei FJ, McCarthy DJ. Anaphylaxis: mechanisms, manifestations, and management. J Foot Surg. 1984 Nov-Dec;23(6):485-8. Review. PubMed PMID: 6084027. 209: Bartolomei FJ, Wertheimer SJ. Intermetatarsal neuromas: distribution and etiologic factors. J Foot Surg. 1983 Winter;22(4):279-82. PubMed PMID: 6643935. CONTRATS ANNÉE 2014 ANR Vibrations (PI Christian Benar & Fabrice Bartolomei ANR « Force » (Responsable Workpackage 2, F Bartolomei & Ch Benar) FHU Epinext A*MIDEX project (ANR-11-IDEX-0001-02)(Dir F Bartolomei) Pôle hospitalier. Neurosciences Cliniques Mis à jour : janvier 2016 21/31 PERSONNELS RATTACHÉS A UNE EQUIPE DE RECHERCHE Regis Jean Carron Romain SERVICES HOSPITALIERS Service de Neurochirurgie Fonctionnelle & Radiochirurgie CONTRATS ANNÉE 2014 J Régis « Evaluation du traitement radiochirurgical gamma knife (GK) bilatéral des noyaux sousthalamiques (NST) chez les patients présentant une Maladie de Parkinson Idiopathique, vérifiant les critères de sélection pour la stimulation cérébrale profonde des NST, et présentant une contreindication à une implantation d’électrodes intra-cérébrales ». AORC 2009-34 + Fondation Avenir J Regis « Evaluation du traitement par Thalamotomie Bilatérale Radiochirurgicale Gamma Knife des patients présentant un tremblement essentiel sevère." AORC 2012 promoteur APHM. J Régis « Traitement des douleurs réfractaires aux opiacés (pallier 3 selon l’OMS) par hypophysiolyse radiochirurgicale : Etude multicentrique prospective et randomisée. » PHRC 2014 RCAPHM13_0388 promoteur APHM. J Régis « Morphométrie Cérébrale et Variabilité Corticale » ANR-09-BLAN-003801BRAINMORPH promotion Université Aix Marseille. 2009. J Régis « Radiochirurgie de l'épilepsie par microfaisceaux synchrotron » ANR-13-BSV1-0012-05 EPIRAD promotion Grenoble C Lançon « Stimulation Cérébrale Profonde chez les patients souffrant d’une dépression résistante et chronique »STHYM PHRC 0804 J Régis « Evaluation clinique et médico économique de la stimulation cérébrale profonde du thalamus dans le traitement des épilépsies partielles pharmacorésistantes (EPPR) inopérables. » STIC FRANCE PUBLICATIONS ANNÉE 2014 1. Bonini F, Burle B, Liegeois-Chauvel C, Regis J, Chauvel P, Vidal F: Action monitoring and medial frontal cortex: leading role of supplementary motor area. Science 343:888-891, 2014. 2. Dubarry AS, Badier JM, Trebuchon-Da Fonseca A, Gavaret M, Carron R, Bartolomei F, Liegeois-Chauvel C, Regis J, Chauvel P, Alario FX, Benar CG: Simultaneous recording of MEG, EEG and intracerebral EEG during visual stimulation: from feasibility to single-trial analysis. Neuroimage 99:548-558, 2014. 3. Fluchere F, Witjas T, Eusebio A, Bruder N, Giorgi R, Leveque M, Peragut JC, Azulay JP, Regis J: Controlled general anaesthesia for subthalamic nucleus stimulation in Parkinson's disease. J Neurol Neurosurg Psychiatry 85:1167-1173, 2014. Pôle hospitalier. Neurosciences Cliniques Mis à jour : janvier 2016 22/31 4. Gaudy-Marqueste C, Carron R, Delsanti C, Loundou A, Monestier S, Archier E, Richard MA, Regis J, Grob JJ: On demand Gamma-Knife strategy can be safely combined with BRAF inhibitors for the treatment of melanoma brain metastases. Ann Oncol 25:2086-2091, 2014. 5. Maillard L, Gavaret M, Regis J, Wendling F, Bartolomei F: Fast epileptic discharges associated with ictal negative motor phenomena. Clin Neurophysiol, 2014. 6. McGonigal A, Bartolomei F, Gavaret M, Chauvel P, Regis J: Gamma Knife Radiosurgery of Paracentral Epilepsy. Stereotact Funct Neurosurg 92:346-353, 2014. 7. Nuttin B, Wu H, Mayberg H, Hariz M, Gabriels L, Galert T, Merkel R, Kubu C, Vilela-Filho O, Matthews K, Taira T, Lozano AM, Schechtmann G, Doshi P, Broggi G, Regis J, Alkhani A, Sun B, Eljamel S, Schulder M, Kaplitt M, Eskandar E, Rezai A, Krauss JK, Hilven P, Schuurman R, Ruiz P, Chang JW, Cosyns P, Lipsman N, Voges J, Cosgrove R, Li Y, Schlaepfer T: Consensus on guidelines for stereotactic neurosurgery for psychiatric disorders. J Neurol Neurosurg Psychiatry, 2014. 8. Regis J: Gamma knife for functional diseases. Neurotherapeutics 11:583-592, 2014. 9. Sevy A, Gavaret M, Trebuchon A, Vaugier L, Wendling F, Carron R, Regis J, Chauvel P, Gonigal AM, Bartolomei F: Beyond the lesion: The epileptogenic networks around cavernous angiomas. Epilepsy Res 108:701-708, 2014. 10. Tuleasca C, Carron R, Resseguier N, Donnet A, Roussel P, Gaudart J, Levivier M, Regis J: Multiple sclerosis-related trigeminal neuralgia: a prospective series of 43 patients treated with gamma knife surgery with more than one year of follow-up. Stereotact Funct Neurosurg 92:203-210, 2014. 11. Tuleasca C, Carron R, Resseguier N, Donnet A, Roussel P, Gaudart J, Levivier M, Regis J: Trigeminal neuralgia related to megadolichobasilar artery compression: a prospective series of twenty-nine patients treated with gamma knife surgery, with more than one year of follow-up. Stereotact Funct Neurosurg 92:170-177, 2014. Pôle hospitalier. Neurosciences Cliniques Mis à jour : janvier 2016 23/31 POLE HOSPITALIER NEUROSCIENCES CLINIQUES PERSONNELS RATTACHÉS A UNE EQUIPE DE RECHERCHE Dr Lucas Troude, Institut des Neurosciences Timone, AMU Dr Anthony Melot, Laoratoire de biomécanique appliquée, Fac Nord, AMU Pr Pierre-Hugues Roche, INT, AMU SERVICES HOSPITALIERS Neurochirurgie CHU Nord APHM - AMU CONTRATS ANNÉE 2014 Investigateur étude CEVOREM – PHRC K 2013 Investigateur étude SUCRE – PHRC 14 – 0514 PUBLICATIONS ANNÉE 2014 de la Rosa Morilla SE, Melot A, Boissonneau S, Farah K, Brunel H, Roche PH. Traumatic intracranial aneurysm secondary to a bullet wound. Clinical case and a review of the literature]. Neurocirugia (Astur). 2015 Nov 14. pii: S1130-1473(15)00098-6. doi: 10.1016/j.neucir.2015.08.001. [Epub ahead of print] Spanish. Troude L Jr, Melot A, Brunel H, Roche PH. Arteriovenous malformation of the filum terminale: an exceptional case. J Neurosurg. 2015 Oct 23:1-4. [Epub ahead of print] Lefebvre A, Saliou P, Lucet JC, Mimoz O, Keita-Perse O, Grandbastien B, Bruyère F, Boisrenoult P, Lepelletier D, Aho-Glélé LS; French Study Group for the Preoperative Prevention of Surgical Site Infections. Preoperative hair removal and surgical site infections: network meta-analysis of randomized controlled trials. J Hosp Infect. 2015 Oct;91(2):100-8. Cassir N, De La Rosa S, Melot A, Touta A, Troude L, Loundou A, Richet H, Roche PH. Risk factors for surgical site infections after neurosurgery: A focus on the postoperative period. Am J Infect Control. 2015 Dec 1;43(12):1288-91. Pôle hospitalier. Neurosciences Cliniques Mis à jour : janvier 2016 24/31 Battaglia F, Plas B, Melot A, Noudel R, Sol JC, Roche PH, Lubrano V. Is there any benefit from short-term perioperative antiepileptic prophylaxis in patients with chronic subdural haematoma? A retrospective controlled study. Neurochirurgie. 2015 Oct;61(5):324-8. Graillon T, Defilles C, Mohamed A, Lisbonis C, Germanetti AL, Chinot O, Figarella-Branger D, Roche PH, Adetchessi T, Fuentes S, Metellus P, Dufour H, Enjalbert A, Barlier A. Combined treatment by octreotide and everolimus: Octreotide enhances inhibitory effect of everolimus in aggressive meningiomas. J Neurooncol. 2015 Aug;124(1):33-43 Lefebvre A, Saliou P, Mimoz O, Lucet JC, Le Guyader A, Bruyère F, Roche PH, Astruc K, Tiv M, Lepelletier D, Aho-Glélé LS; French Study Group for the Pre-operative Prevention of Surgical Site Infections. Is surgical site scrubbing before painting of value? Review and meta-analysis of clinical studies. J Hosp Infect. 2015 Jan;89(1):28-37. Grapperon AM, Franques J, Roche PH, Battaglia F. Does hereditary neuropathy with liability to pressure palsy predispose to schwannomatosis? J Clin Neurol. 2014 Oct;10(4):371-2. Bruyère F, Lefebvre A, Saliou P, Mimoz O, Lucet JC, Le Guyader A, Roche P, Lepelletier D, AhoGlélé LS. [Update of the 2013 consensus conference "Management of the preoperative risk of infection"]. Prog Urol. 2014 Jul;24(9):545-50. Mishra AK, Dufour H, Roche PH, Lonjon M, Raoult D, Fournier PE. Molecular revolution in the diagnosis of microbial brain abscesses. Eur J Clin Microbiol Infect Dis. 2014 Dec;33(12):2083-93 Fritz S, Cassir N, Noudel R, De La Rosa S, Roche PH, Drancourt M. Postsurgical Pantoea calida meningitis: a case report. J Med Case Rep. 2014 Jun 16;8:195 Meling TR, Proust F, Gruber A, Niemela M, Regli L, Roche PH, Vajkoczy P. On apples, oranges, and ARUBA. Acta Neurochir (Wien). 2014 Sep;156(9):1775-9. Lepelletier D, Saliou P, Lefebvre A, Lucet JC, Grandbastien B, Bruyère F, Stahl JP, Keita-Perse O, Berthelot P, Aho S; workgroup SF2H. "Preoperative risk management: strategy for Staphylococcus aureus preoperative decolonization" (2013 update). French society of Hospital Hygiene. Med Mal Infect. 2014 Jun;44(6):261-7. Vincent N, Roche PH, Devèze A. An unusual and severe complication of skull base surgery. Eur Ann Otorhinolaryngol Head Neck Dis. 2014 Apr;131(2):147-9. Forest F, N'guyen AT, Fesselet J, Metellus P, Bouvier C, de Paula AM, Roche PH, Figarella-Branger D. Meningeal Rosai-Dorfman disease mimicking meningioma. Ann Hematol. 2014 Jun;93(6):937-40 Roche PH, Troude L, Peyriere H, Noudel R. The epidural approach to the Meckel's cave: a how I do it. Acta Neurochir (Wien). 2014 Jan;156(1):217-20. Pôle hospitalier. Neurosciences Cliniques Mis à jour : janvier 2016 25/31 POLE HOSPITALIER NEUROSCIENCES CLINIQUES PERSONNELS RATTACHÉS A UNE EQUIPE DE RECHERCHE Olivier CHINOT (PU-PH) Inserm UMR 911 Equipe 4 Emeline TABOURET (CCA) Inserm UMR 911 Equipe 4 SERVICES HOSPITALIERS Service de Neuro-Oncologie THESES DE DOCTORAT ANNÉE 2014 TABOURET Emeline : « Glioblastome et angiogénèse : profils évolutifs, interaction avec l’invasivité et implication thérapeutiques » ; 15 Juin 2015 CONTRATS ANNÉE 2014 - O. Chinot: “Metalloproteases MMP2 and MMP9 prebiomarkers of bevacizumab benefit: Tentative of validation in the setting of AVAglio Phase III trial” F Hoffman-La Roche LTD, 2014 - D. Figarella-Branger et O. Chinot: « Labellisation du SIRIC Marseille : Programme Gliomes » INCa-DGOS-Inserm 6038, 2012-2016 - O. Chinot et D. Figarella-Branger: « Molecular genetic, host-derived and clinical determinants of long term survival in glioblastoma”. Contrat international (Brain Tumor Fondation et EORTC, 2014) - G. Rougon, D. Figarella-Branger, M. Malissen, O. Chinot: « Biologie et Sciences du Cancer »: «Study of the dynamics of inflammation in glioblastomas in a pre-clinical model by a combined approach with biphotonic spectral imaging in vivo and multiparametric cytometry, validation in patients» INSERM-INCa Projets libres de Recherche « Biologie et Sciences du Cancer » T. Leroy : « Déterminants des inégalités sociales d’ajustement du patient et de son principal aidant naturel face aux cancers du système nerveux central (ISAPA-SNC), Inca-SHS 2013 M. Sanson : « A Phase I/II, Open-Label, multicentre study to assess the safety, tolerability, pharmacokinetics and clinical efficacy of AZD4547 in patients with relapsed/refractory glioma positive for an FGFR fusion TARGET, PHRC 2014 BREVETS ANNÉE 2014 “MMP2 as a predictive biomarker of response to anti-angiogenic therapy and survival after therapy in cancer patients”. Inventors: O. Chinot and E. Tabouret . Université d’Aix-Marseille and Assistance Publique-Hôpitaux de Marseille. SAAT Sud-est. Patent Application Europe No. 12305565.9 filled Mai 23, 2014. USA extension No. 14/402913 and Japon. PUBLICATIONS ANNÉE 2014 1. Ait-Belkacem R, Berenguer C, Villard C, Ouafik L, Figarella-Branger D, Beck A, Chinot O, Lafitte D. Monitoring therapeutic monoclonal antibodies in brain tumor. MAbs. 2014 Nov 2;6(6):1385-93. (IF 4.726) 2. Berges R, Baeza-Kallee N, Tabouret E, Chinot O, Petit M, Kruczynski A, Figarella-Branger D, Honore S, Braguer D. End-binding 1 protein overexpression correlates with glioblastoma progression and sensitizes to Vinca-alkaloids in vitro and in vivo. Oncotarget. 2014 Dec 30;5(24):12769-87. (IF 6.627) 3. Chinot OL, Reardon DA. The future of antiangiogenic treatment in glioblastoma.Curr Opin Neurol. 2014 Dec;27(6):675-82. (IF 3.761)) 4. Chinot OL. Cilengitide in glioblastoma: when did it fail? Lancet Oncol. 2014 Sep;15(10):1044-5. (IF 24.725) 5. Tabouret E, Chinot O, Sanson M, Loundou A, Hoang-Xuan K, Delattre JY, Idbaih A. Predictive biomarkers investigated in glioblastoma. Expert Rev Mol Diagn. 2014 Sep;14(7):883-93. (IF 4.270) Pôle hospitalier. Neurosciences Cliniques Mis à jour : janvier 2016 26/31 6. Weller M, van den Bent M, Hopkins K, Tonn JC, Stupp R, Falini A, Cohen-Jonathan-Moyal E, Frappaz D, Henriksson R, Balana C, Chinot O, Ram Z, Reifenberger G, Soffietti R, Wick W; European Association for Neuro-Oncology (EANO) Task Force on Malignant Glioma. EANO guideline for the diagnosis and treatment of anaplastic gliomas and glioblastoma. Lancet Oncol. 2014 Aug;15(9):e395-403. (IF 24.725) 7. Chinot OL, Wick W, Cloughesy T. Bevacizumab for newly diagnosed glioblastoma. N Engl J Med. 2014 May 22;370(21):2049. (IF 54.420) 8. Lagarde S, Tabouret E, Matta M, Franques J, Attarian S, Pouget J, Maues De Paula A, Figarella-Branger D, Dory-Lautrec P, Chinot O, Barrié M. Primary neurolymphomatosis diagnosis and treatment: a retrospective study. J Neurol Sci.2014 Jul 15;342(1-2):178-81. (IF 2.262) 9. Tabouret E, Coso D, Matta M, Barrié M, Bouabdallah R, Chinot O. Bing-Neel syndrome: a cerebral Richter syndrome? Neurol India. 2014 Mar-Apr;62(2):229-30. (IF 1.084) 10. Laffaire J, Di Stefano AL, Chinot O, Idbaih A, Gallego Perez-Larraya J, Marie Y, Vintonenko N, Boisselier B, Farina P, Delattre JY, Figarella-Branger D, Honnorat J, Sanson M, Ducray F. An ANOCEF genomic and transcriptomic microarray study of the response to irinotecan and bevacizumab in recurrent glioblastomas.Biomed Res Int. 2014;2014:282815. (IF 2.710) 11. Figarella-Branger D, Mokhtari K, Dehais C, Jouvet A, Uro-Coste E, Colin C, Carpentier C, Forest F, Maurage CA, Vignaud JM, Polivka M, Lechapt-Zalcman E, Eimer S, Viennet G, Quintin-Roué I, Aubriot-Lorton MH, Diebold MD, Loussouarn D, Lacroix C, Rigau V, Laquerrière A, Vandenbos F, Michalak S, Sevestre H, Peoch M, Labrousse F, Christov C, Kemeny JL, Chenard MP, Chiforeanu D, Ducray F, Idbaih A; POLA Network. Mitotic index, microvascular proliferation, and necrosis define 3 groups of 1p/19q codeleted anaplastic oligodendrogliomas associated with different genomic alterations. Neuro Oncol. 2014 Sep;16(9):1244-54. (IF 5.286) 12. Chauffert B, Feuvret L, Bonnetain F, Taillandier L, Frappaz D, Taillia H, Schott R, Honnorat J, Fabbro M, Tennevet I, Ghiringhelli F, Guillamo JS, Durando X, Castera D, Frenay M, Campello C, Dalban C, Skrzypski J, Chinot O. Randomized phase II trial of irinotecan and bevacizumab as neo-adjuvant and adjuvant to temozolomide-based chemoradiation compared with temozolomide-chemoradiation for unresectable glioblastoma: final results of the TEMAVIR study from ANOCEF†. Ann Oncol. 2014 Jul;25(7):1442-7 (IF 6.578) 13. Chinot OL, Wick W, Mason W, Henriksson R, Saran F, Nishikawa R, Carpentier AF, Hoang-Xuan K, Kavan P, Cernea D, Brandes AA, Hilton M, Abrey L, Cloughesy T. Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma. N Engl J Med. 2014 Feb 20;370(8):709-22. (IF 54.420) 14. Zouaoui S, Darlix A, Fabbro-Peray P, Mathieu-Daudé H, Rigau V, Fabbro M, Bessaoud F, Taillandier L, Ducray F, Bauchet F, Wager M, Faillot T, Capelle L, Loiseau H, Kerr C, Menei P, Duffau H, Figarella-Branger D, Chinot O, Trétarre B, Bauchet L. Oncological patterns of care and outcomes for 265 elderly patients with newly diagnosed glioblastoma in France. Neurosurg Rev. 2014 Jul;37(3):415-23; (IF 1.861) 15. Ait-Belkacem R, Berenguer C, Villard C, Ouafik L, Figarella-Branger D, Chinot O, Lafitte D. MALDI imaging and in-source decay for top-down characterization of glioblastoma. Proteomics. 2014 May;14(10):1290-301. 16. Jiguet Jiglaire C, Baeza-Kallee N, Denicolaï E, Barets D, Metellus P, Padovani L, Chinot O, Figarella-Branger D, Fernandez C. Ex vivo cultures of glioblastoma in three-dimensional hydrogel maintain the original tumor growth behavior and are suitable for preclinical drug and radiation sensitivity screening. Exp Cell Res. 2014 Feb 15;321(2):99-108. (IF 3.973) 17. Reyes-Botero G, Dehais C, Idbaih A, Martin-Duverneuil N, Lahutte M, Carpentier C, Letouzé E, Chinot O, Loiseau H, Honnorat J, Ramirez C, Moyal E, Figarella-Branger D, Ducray F; POLA Network. Contrast enhancement in 1p/19q-codeleted anaplastic oligodendrogliomas is associated with 9p loss, genomic instability, and angiogenic gene expression. Neuro Oncol. 2014 May;16(5):662-70. (IF 5.286) 18. Tabouret E, Boudouresque F, Barrie M, Matta M, Boucard C, Loundou A, Carpentier A, Sanson M, Metellus P, Figarella-Branger D, Ouafik L, Chinot O. Association of matrix metalloproteinase 2 plasma level with response and survival in patients treated with bevacizumab for recurrent high-grade glioma. Neuro Oncol. 2014 Mar;16(3):392-9. (IF 5.286) Pôle hospitalier. Neurosciences Cliniques Mis à jour : janvier 2016 27/31 POLE HOSPITALIER NEUROSCIENCES CLINIQUES PERSONNELS RATTACHÉS A UNE EQUIPE DE RECHERCHE Pr. Mathieu CECCALDI, PUPH Dr. Mira DIDIC, PH Pr. Olivier FELICIAN, PUPH Mme Eve TRAMONI-NEGRE, Psychologue Neuropsychologue SERVICES HOSPITALIERS Service de Neurologie et Neuropsychologie THESES DE DOCTORAT ANNÉE 2014-15 DUFOURNET Boris « Maladie d’Alzheimer avec ou sans cooccurrence d’autres maladies Neurodégénératives. Étude préliminaire menée à partir des archives du Laboratoire d’Anatomopathologie et de Neuropathologie du CHU de la Timone » ; soutenue le 6 octobre 2015. PUBLICATIONS ANNÉE 2014-15 1. Jessen F, Amariglio RE, van Boxtel M, Breteler M, Ceccaldi M, Chételat G, Dubois B, Dufouil C, Ellis KA, van der Flier WM, Glodzik L, van Harten AC, de Leon MJ, McHugh P, Mielke MM, Molinuevo JL, Mosconi L, Osorio RS, Perrotin A, Petersen RC, Rabin LA, Rami L, Reisberg B, Rentz DM, Sachdev PS, de la Sayette V, Saykin AJ, Scheltens P, Shulman MB, Slavin MJ, Sperling RA, Stewart R, Uspenskaya O, Vellas B, Visser PJ, Wagner M; Subjective Cognitive Decline Initiative (SCD-I) Working Group. A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer's disease. Alzheimers Dement 2014; 10(6): 844-52. 2. Robert PH, König A, Amieva H, Andrieu S, Bremond F, Bullock R, Ceccaldi M, Dubois B, Gauthier S, Kenigsberg PA, Nave S, Orgogozo JM, Piano J, Benoit M, Touchon J, Vellas B, Yesavage J, Manera V. Recommendations for the use of Serious Games in people with Alzheimer's Disease, related disorders and frailty. Front Aging Neurosci 2014; 6: 54. 3. Mosbah A, Tramoni E, Guedj E, Aubert S, Daquin G, Ceccaldi M, Felician O, Bartolomei F. Clinical, neuropsychological, and metabolic characteristics of transient epileptic amnesia syndrome. Epilepsia 2014; 55(5): 699-706. 4. De Anna F, Felician O, Barbeau E, Mancini J, Didic M, Ceccaldi M. Cognitive changes in mild cognitive impairment patients with impaired visual recognition memory. Neuropsychology 2014; 28(1): 98-105. 5. Gour N, Felician O, Didic M, Koric L, Gueriot C, Chanoine V, Confort-Gouny S, Guye M, Ceccaldi M, Ranjeva JP. Functional connectivity changes differ in early and late-onset Alzheimer's disease. Hum Brain Mapp 2014; 35(7): 2978-94. 6. Lattante S, Le Ber I, Galimberti D, Serpente M, Rivaud-Péchoux S, Camuzat A, Clot F, Fenoglio C; French research network on FTD and FTD-ALS, Scarpini E, Brice A, Kabashi E. Defining the association of TMEM106B variants among frontotemporal lobar degeneration patients with GRN mutations and C9orf72 repeat expansions. Neurobiol Aging 2014; 35(11): 2658.e1-5. doi: 10.1016/j.neurobiolaging.2014.06.023. Pôle hospitalier. Neurosciences Cliniques Mis à jour : janvier 2016 28/31 7. Jovicich J, Marizzoni M, Bosch B, Bartrés-Faz D, Arnold J, Benninghoff J, Wiltfang J, Roccatagliata L, Picco A, Nobili F, Blin O, Bombois S, Lopes R, Bordet R, Chanoine V, Ranjeva JP, Didic M, Gros-Dagnac H, Payoux P, Zoccatelli G, Alessandrini F, Beltramello A, Bargalló N, Ferretti A, Caulo M, Aiello M, Ragucci M, Soricelli A, Salvadori N, Tarducci R, Floridi P, Tsolaki M, Constantinidis M, Drevelegas A, Rossini PM, Marra C, Otto J, Reiss-Zimmermann M, Hoffmann KT, Galluzzi S, Frisoni GB; PharmaCog Consortium. Multisite longitudinal reliability of tractbased spatial statistics in diffusion tensor imaging of healthy elderly subjects. Neuroimage 2014; 101: 390-403. 8. Della Rosa PA, Cerami C, Gallivanone F, Prestia A, Caroli A, Castiglioni I, Gilardi MC, Frisoni G, Friston K, Ashburner J, Perani D; EADC-PET Consortium. A standardized [18F]-FDG-PET template for spatial normalization in statistical parametric mapping of dementia. Neuroinformatics 2014; 12(4): 575-93. 9. 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