! SMARTT!e(Patch,!a!new!electronic!transdermal!patch,! is!a!winner

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SMARTT!e(Patch,!a!new!electronic!transdermal!patch,!
is!a!winner!at!the!French!‘Worldwide!Innovation!
Challenge’!!
!
Rhenovia!achieved!award!recognition!in!the!‘personalized!medicine’!
category!for!its!SMARTT!e(Patch!
Mulhouse,!France,!April!22!2014!–!Rhenovia!Pharma,!a!biotechnology!company!specialized!
in! the! application! of! biosimulation! to! the! research! and! development! of! new! medicinal!
products,!today!announces!that!its!SMARTT!e@Patch!project!has!won!an!award!at!the!‘World!
Innovation! Challenge’;! founded! by! the! President! of! France! to! identify! future! champions! in!
the!French!economy.!
!
The!innovative!patch!caters!to!the!need!for!controlled!administration!of!medicinal!products!
in!treating!chronic!conditions!such!as!Alzheimer’s!disease.!Support!from!the!French!State's!
program!of!investment!for!the!future!will!help!to!industrialize!the!production!of!the!patch!
within!five!years.!The!world!market!in!this!field!is!estimated!to!exceed!EUR!22!billion!(USD!
31.5!billion)!by!2015!(source:!MarketsandMarkets,!April!2013)!
SMARTT!e(Patch:!responding!to!public!health!demand!
A! combination! of! population! aging! and! various! environmental! factors! are! leading! to! the!
proliferation!of!chronic!conditions!such!as!vascular,!inflammatory!and!neurological!disease.!
Currently,! around! fifty! per! cent! of! patients! fail! to! take! orally@administered! drugs! correctly!
(WHO,!2012).!The!use!of!chronobiological!polytherapies!and!controlled!dosages!is!therefore!
essential!for!a!growing!majority!of!patients.!Rhenovia’s!electronic!transdermal!patch!offers!a!
solution!that!can!automate!the!administration!of!essential!medicinal!products.!
The!SMARTT!e@Patch!is!a!transdermal!patch,!which!allows!the!controlled!administration!of!
up!to!seven!medicinal!products!through!the!use!of!an!inbuilt!electronic!system!programmed!
by! the! treating! physician.! Initially! designed! to! make! it! easier! for! patients! suffering! from!
nervous!system!disorders!such!as!Alzheimer’s!to!take!medicinal!products,!Rhenovia’s!patch!
can!be!extended!to!support!a!significantly!larger!range!of!conditions.!!
By! enabling! the! chronobiological! administration! and! controlled! dosage! of! medicinal!
products,! it! has! the! effect! of! increasing! efficacy,! improving! bioavailability! and! minimizing!
side!effects.!The!transdermal!patch!also!prevents!doses!being!missed!or!taken!erratically!by!
patients!who!are!confused,!or!who!require!third!party!assistance.!
SMARTT!e(Patch!awarded!by!the!French!state!
The! Innovation! Commission! 2030! is! chaired! by! internationally@renowned! French!
businesswoman! Anne! Lauvergeon.! It! was! .set! up! in! April! 2013! to! identify! seven! thematic!
objectives! based! on! major! societal! expectations! and! growth! sectors.! These! objectives! will!
form! the! essential! pillars! to! ensure! long@term! prosperity! and! employment! in! France.! The!
French!State!launched!the!World!Innovation!Challenge!on!December!2,!2013!to!support!and!
develop!the!future!champions!of!the!French!economy.!
As!part!of!the!Challenge,!a!first!wave!of!625!innovative!international!projects!was!submitted!
to!French!public!investment!bank!BPIFrance.!Of!these,!134!were!shortlisted!and!58!made!the!
final! selection.! The! list! of! winners! was! revealed! on! March! 20,! 2014! by! France’s! Prime!
Minister.! There! were! 13! award@winners! in! the! strategic! area! of! personalized! medicine,!
including!Rhenovia’s!SMARTT!e@Patch!project.!
!
A!market!worth!several!tens!of!billions!of!euros!(!and!rising!
The!world!market!for!the!transdermal!administration!of!medicinal!products!is!valued!at!USD!
31.5!billion!(EUR!22.8!billion)!for!2015!(source:!MarketsandMarkets,!April!2013),!with!annual!
growth! of! around! 8%.! Of! equal! interest! to! the! pharmaceutical! industry! and! to! health!
authorities!and!patient!groups,!transdermal!administration!is!set!to!account!for!17%!of!the!
world! market! for! medicinal! product! administration! by! 2017.! These! forecasts! are! based! on!
the! use! of! passive! transdermal! patches! only,! which! do! not! offer! the! advantages! of! the!
solution!developed!by!Rhenovia.!
A!patented!procedure!using!advanced!technologies!
A! patent! was! filed! in! 2012! for! Rhenovia’s! intelligent! transdermal! patch.! It! combines! a!
number! of! technological! innovations,! including! an! ultra@slim! battery,! a! printed! electronic!
circuit! on! a! flexible! substrate,! UV@LED! ink,! a! novel! photolabile! ligand,! transdermal!
nanovectors!and!non@contact!programming.!!
“In# singling# out# the# SMARTT# e2Patch# project,# the# World# Innovation# Challenge# panel# has#
highlighted# the# innovative# nature# of# our# intelligent# transdermal# patch# and# the#
appropriateness# of# its# response# to# a# major# health# challenge# and# its# huge# commercial#
potential,”! said! Serge! Bischoff,! CEO! of! Rhenovia.! “The# support# of# the# French# government,#
and# the# engagement# of# our# partners,# particularly# in# the# Alsace# region,# mean# that# we# can#
now#accelerate#its#development#and#plan#for#market#launch#in#less#than#five#years.”!!
The!development!of!Rhenovia’s!transdermal!patch!will!result!in!the!creation!of!a!new!entity!
to! raise! the! funds! required! for! its! development! and! secure! strategic! partnerships! with!
industry! players! in! the! health! care! sector.! Meanwhile,! Rhenovia,! a! world! leader! in! central!
nervous! system! biosimulation*,! will! continue! its! development! in! the! research! and!
development!markets!for!medicinal!products,!agri@food!and!defense.!
#
*#“Global#Biosimulation#Technology#Market#(201222017)”#study#from#MarketsandMarkets,#November#2012.#
!
About!Rhenovia!Pharma!SAS!
Rhenovia!Pharma!SAS!is!a!French!biotechnology!company!founded!in!2007!by!an!international!team!
that! brings! together! managers! from! large! pharmaceutical! companies! and! world! experts! in!
neuroscience! and! nervous! system! modeling.! The! company! is! the! world! leader!in!the!application!of!
biosimulation! to! the! prevention! and! treatment! of! neurological,! neurodegenerative! and! psychiatric!
disorders!and!diseases.!!
Based! in! Mulhouse,! France,! Rhenovia! today! has! around! twenty! members! of! staff! in! France,!
Switzerland,!Germany!and!the!US,!where!it!opened!a!subsidiary!in!2012.!
!
Find!out!more:!http://www.rhenovia.com!!
!
!
Andrew!Lloyd!&!Associates!
Juliette!dos!Santos!/!Sarah!Morgan!
+!44!1273!675!100!
[email protected]!@[email protected]!
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