INS ASM 2013 programme - University of Limerick

Transcription

INS ASM 2013 programme - University of Limerick
University Hospitals Limerick (UHL)
Annual Research Symposium
2015
Friday October 09th, 2015
Strand Hotel, Limerick
Ireland
Welcome!
On behalf of the Organising Committee, it gives me great pleasure once again to welcome you to
the 2015 University Hospitals Limerick Annual Research Symposium at the Strand Hotel, Limerick.
This is our third major symposium and follows on from very successful scientific meetings in 2013
and 2014. Importantly, it demonstrates the continued growth in research capability and diversity
across our Hospital network and University departments.
We have had an enthusiastic response from our research community with over 190 scientific abstracts
including 18 oral presentations. The Scientific Committee has taken great care in preparing a highquality and varied programme that will feature the latest developments and ideas in Health
Services & Population Health, Lifestyle & Health, Technology & Health and Clinical Research.
Poster presentations will be set up by 9.00am on Friday morning and on view until 5pm. Authors are
requested to be present at their posters during the lunch and coffee breaks so please take time to
view and discuss their work.
We have an exciting line up of invited national and international speakers along with a welcoming
address from Professor Don Barry, President of University of Limerick. Our aim this year is to
further exploit our potential as an academic institution and highlight our recent research
accomplishments. Finally, we are very grateful to our very generous sponsors whose continued
support has made this meeting possible.
We hope that you enjoy the meeting and look forward to meeting you on the day!
Professor Austin Stack,
Chair Organising Committee
University Hospitals (UL) Limerick
Annual Research Symposium
Friday 09th October 2015
08.00am
08.45am- 9.00am
Poster & Stand set-up----------- Coffee & Registration
Welcome Address
Professor Austin Stack
Foundation Chair of Medicine, Graduate Entry Medical School, University Of Limerick
&
Professor Don Barry
President, University Of Limerick
Session 1
9:00am – 11:10am
Invited Speaker (IRE)
Chair: Professor Austin Stack
09.00am–09.45am
“Research, Knowledge and Evidence: A Policy Perspective”
Dr Tony Holohan
Chief Medical Officer, Department of Health and Children, Ireland
Session 1 - Chairs: Dr Damien Ryan and Prof Austin Stack
09.50 The changing epidemiology of newly diagnosed HIV infections in Clare, Limerick &
Tipperary North, 2010 to 2014.
Presenter: Keith Ian Quintyne
10.00 Innovation in health services delivery: Do we need radical innovation to address social
inequalities in access to, and potential to benefits from health services?
Presenter: Eileen Humphreys
10.10 Significant variation in blood transfusion practice persists following Idiopathic Adolescent
Scoliosis surgery.
Presenter: Sandra O’Malley
10.20 We do fun things together: How adults with intellectual disabilities in Ireland navigate
stigma to create lasting friendships.
Presenter: Geraldine Shiels
10.30 Assessing the effectiveness of CPR on a manikin with a feedback device.
Presenter: Eoghan Connolly
10.40 Risk of Acute Coronary Events and Coronary Interventions for Overweight and Obese
patients versus normal weight patients undergoing Dialysis; A National Study.
Presenter: Clare Miller
_________________________________________________________________________________________
10.50am-11.10am
Coffee/Tea Break
Session 2
11:10am-2.00pm
Invited Speaker (CAN)
Chair: Dr Damien Ryan
11.10am–11.55am
“Jump Starting Research in Resuscitation: A Canadian Story”
Professor Laurie Morrison
Robert & Dorothy Pitts Research Chair in Acute Care & Emergency Medicine,
Professor and Clinician Scientist in the Division of Emergency Medicine,
Department of Medicine at the University of Toronto and
Li Shing Knowledge Institute at St. Michael’s Hospital,
Canada
________________________________________________________________________________
12.00pm-1.00pm
Networking Lunch and Poster Viewing
________________________________________________________________________________
Session 2 – Chairs: Mr Brian Lenehen, Dr Phil Hodnett and Dr Damien Ryan
1.00
Development of a Novel Test of Visuospatial Cognition: The Letter and Shape Drawing
Test. A study of performance in Hospitalised Elderly Patients and Young Healthy Adults.
Presenter: Debbie White
1.10
A Microfluidic Platform for analysis of treatment of E. Coli and Breast Cancer cell models.
Presenter: Marie Keays
1.20
Identification of Genetic Biomarkers for Metastatic Colorectal Cancer.
Presenter: Christopher Hayes
1.30
Employing a Software Quality Plan within a Distributed Team Environment.
Presenter: Noel Carroll
1.40
An in vitro bioassay to study the bioactivities of nutrient compounds for hypertrophy
and/or recovery of skeletal muscle.
Presenter: Sylvia Murphy
1.50
High throughput screening for combinational drug discovery.
Presenter: Finola Cliffe
Session 3
2.05pm– 4.10pm
Invited Speaker (IRE)
2.05pm-2.55pm:
Chair: Prof Paul Finucane
“The mesentery in Crohn’s disease – friend or foe”
Professor J Calvin Coffey
Foundation Chair Surgery,
Graduate Entry Medical School, University of Limerick
Consultant General and Colorectal Surgeon, University Hospitals Limerick
_________________________________________________________________________________
2.55pm-3.10pm
Coffee/Tea Break
_________________________________________________________________________________
Session 3 - Chairs: Prof Paul Finucane and Prof Austin Stack
3.10
Management of a positive sentinel lymph node at University Hospital Limerick–
Oncological patterns of care.
Presenter: David Lynch
3.20
Glycaemic Control Is Comparable In Patients with or without Significant Hepatic Fibrosis
As Assessed By NAFLD Fibrosis Score.
Presenter: Zeshan Siddiqui
3.30
A review of thyroid sonographic features and international guidelines; ability to
differentiate benign and malignant nodules.
Presenter: Arlene Weir
3.40
Usefulness of Ultrasound in Evaluating the Recovery of Diaphragm Paralysis.
Presenter: Shahzaib Saleem
3.50
High sensitive troponin t levels following elective external direct current cardioversion
for atrial fibrillation and atrial flutter.
Presenter: Ronstan Lobo
4.00
Public health benefits of commuter cycling in urban environments – infrastructure
modification and bike-share for facilitating mode shift.
Presenter: Bradley Taylor
Invited Speaker (IRE)
Chair: Mr Brian Lenehan
4.15pm-5.00pm
“The Idea of a Research Institute - scientific highlights from mining the microbiome”
Professor Fergus Shanahan
Professor and Chairman of the Department of Medicine,
University College Cork (UCC), Cork, Ireland
5.00pm-5.30pm
Prize Presentation with Invited Speakers
5.30pm-6.00pm
Relax
6.00pm-6:45pm
Reception on Level 6 followed by Dinner in City View Suite at 7pm.
Speaker Biographies
Dr Tony Holohan
Dr Tony Holohan was appointed as Chief Medical Officer in December 2008.
responsibilities include:
1.
2.
3.
4.
5.
6.
7.
8.
9.
His
Leading on patient safety and quality in health care
Leading on public health (health promotion, health protection including emergency
planning, health improvement)
Leading on reproductive health and social inclusion
Providing expert medical evidence, analysis and advice to the Minister, Ministers of
State and to the Department
Contributing to the development and implementation of policy and services in relation
to the health services as a whole
Working with the medical profession on policy and professional matters and playing a
lead role in maintaining good working relationships between the Department and the
profession
Developing good working relationships with relevant external agencies and
stakeholders, both nationally and internationally, particularly the HSE, HIQA and the
Medical Council
Communicating Departmental positions in the media and at national and international
fora
Providing a high quality training environment and experience for the Specialist Training
Programme in Public Health.
Dr Tony Holohan qualified from UCD in 1991 and trained initially in General Practice and
subsequently in public health medicine. He was appointed as Deputy Chief Medical Officer
at the Department of Health and Children in 2001 where he worked on the Health Strategy,
Primary Care Strategy National Health Information Strategy. He has more recently worked
on the new National Cancer Control Strategy as a member of the National Cancer Forum.
He is also a member of the National Cancer Registry Board and the Health Research Board.
He has previously been a member of the Board of the Faculty of Public Health Medicine.
Professor Laurie Morrison
Dr. Laurie Morrison is the Robert & Dorothy Pitts Research Chair in Acute Care &
Emergency Medicine, Professor and Clinician Scientist in the Division of Emergency
Medicine, Department of Medicine at the University of Toronto and Li Ka Shing Knowledge
Institute at St Michael’s Hospital.
She is the Director of Rescu, a resuscitation research program focusing on the evaluation
and implementation of prehospital and transport medicine time sensitive interventions in
acute emergencies (www.rescu.ca). She conducts systematic reviews and meta-analyses in
topics pertaining to Acute Coronary Syndrome and Resuscitation and has established a
collaborative network to conduct randomized controlled trials and outcome validation
studies in prehospital resuscitation research. She is a US National Institute of Health,
Canadian Institute of Health Research and Heart and Stroke Canada funded investigator
within the Resuscitation Outcomes Consortium.
She is a past Chair and current member of the Advanced Cardiac Life Support committee of
the American Heart Association and on the Editorial Board of the 2010 guidelines in
Resuscitation as the Co-Chair of the International Liaison Committee of Resuscitation
Advance Life Support Taskforce in 2010. She is the current chair of the Research and Policy
Planning Advisory Committee for Heart and Stroke Canada. She was born and educated in
Peterborough Ontario, completed her undergraduate at Queens and her medical degree at
McMaster. She completed postgraduate training in Emergency Medicine at McGill prior to
completing her fellowship at U of T and returning to McMaster in 2000 to obtain a graduate
degree in health research design. She has received the Canadian Medical Association award
in mentorship; the May Cohen award and was recently celebrated for excellence in
mentorship at U of T with the Department of Medicine Bob Hyland award.
Research Interests: Prehospital and transport medicine, resuscitation research, medical
futility decision rules, emergency health care delivery, acute coronary syndrome, cardiac
arrest, life threatening trauma
Professor J Calvin Coffey
Professor Calvin Coffey is Foundation Chair of Surgery at the Graduate Entry Medical School
(GEMS), University of Limerick and Consultant Colorectal Surgeon at University Hospital
Limerick, Ireland. His clinical focus is in colorectal cancer, inflammatory bowel disease
(ulcerative colitis and Crohn’s disease), and pelvic floor abnormalities. Professor Coffey is
Deputy Director of 4i Research Centre, at the Graduate Entry Medical School, University of
Limerick where scientific studies are directed at exploring innovations in the pathobiology,
prevention and treatment of infection, inflammation and immunology.
He is the recipient of the international James IV Travelling Fellowship Award for his work in
colorectal cancer surgery and his scientific research in the field. In 2012 he was recipient of
the Cleveland Clinic Distinguished Alumnus award. He is also the recipient of over 45
national and international awards, has over 180 publications and has delivered several
named national and international lectures (Millin lecture, 2012, Sir Thomas Myles Lecture
2011, inaugural Young Investigator Lecture at the Surgical Infection Society of Europe).
After initially training in Cork University Hospital, where he received a PhD for work on
cancer growth, he then trained in the Mater Misericordiae Hospital; St.Vincent’s University
Hospital and finally completed a fellowship in colorectal surgery at the Cleveland Clinic. He
has delivered invited lectures in The Johns Hopkins, Memorial Sloan Kettering, The
Cleveland Clinic and The European Institute of Oncology. Professor Coffey Foundation
Chair of Surgery at the Graduate Entry Medical School, University of Limerick and University
Hospitals Limerick. Professor Coffey is a general and colorectal surgeon with a special
interest in minimally invasive (keyhole) surgery. His clinical focus is in colorectal cancer,
inflammatory bowel disease (ulcerative colitis and Crohn’s disease), pelvic floor
abnormalities.
Professor Fergus Shanahan
Fergus Shanahan MD, DSc, is Professor and Chairman of the Department of Medicine and
Director of the APC Microbiome Institute at University College Cork (UCC). The APC
investigates host-microbe interactions in health and disease, now has a membership of
over 170 staff, scientists and students, and is funded by Science Foundation Ireland and by
research alliances with companies within the food and pharmaceutical sectors.
Dr. Shanahan attended medical school at University College Dublin. After internship and
residency at the Mater hospital, he completed fellowships in clinical immunology at
McMaster University, Canada, and in gastroenterology at University of California, Los
Angeles (UCLA). At UCLA he rose to the rank of Associate Professor with tenure before
returning to Ireland in 1993.
Dr. Shanahan has published over 450 scientific papers and has co-edited several books. He
has also published several articles on the medical humanities, including an award winning
essay entitled ‘Waiting’. He is a Fellow of the Royal College of Physicians in Ireland, Canada,
and the United Kingdom as well as of the American College of Physicians. He is a former
President of the Irish Society of Gastroenterology, was named to the “Irish Life Science 50”
a list of the top 50 Irish and Irish Americans in the life science industry, and recently was
awarded the Irish Society of Immunology medal and public lecture award. In 2013, Science
Foundation Ireland named him as its Researcher of the Year. His interests include mucosal
immunology, gut microbiota, inflammatory bowel disease, and most things that affect the
human experience.
Organising Committee UHL Research Symposium
Professor Austin Stack, Chair of Medicine, Consultant Nephrologist, University Hospital Limerick
Mr Brian Lenehan, Consultant Orthopaedic Surgeon, University Hospital Limerick
Dr Damien Ryan, Consultant in Emergency Medicine, University Hospital Limerick
Professor Paul Finucane, Chief Academic Officer, University Hospitals Limerick
Ms Mary Clarke Moloney, Clinical Operations Manager, Health Research institute (HRI), UL
Ms Maire Bhreathnach, Graduate Entry Medical School, UL
Ms Karen Kemmy, Health Research Institute, UL
Scientific Review Committee
Prof Colum Dunne, Foundation Chair & Director of Research, Graduate Entry Medical School, UL
Prof Paul Finucane, Chief Academic Officer, University Hospital Limerick
Dr Tony Moloney, Vascular/Endovascular Surgeon, University Hospital Limerick
Dr Philip Hodnett, Consultant Radiologist, University Hospital Limerick
Mr Brian Lenehan, Consultant Orthopaedic Surgeon, University Hospital Limerick
Dr Damien Ryan, Consultant in Emergency Medicine, University Hospital Limerick
Dr Patrick Kiely, Lecturer, Dept of Life Sciences, UL
Prof Fiona Murphy, Professor of Nursing & Midwifery, EHS, UL
Dr Julie O’Brien, Consultant Radiologist, University Hospital Limerick
Prof Mike Watts, Consultant Physician Acute Medicine, University Hospital Limerick
Prof Catriona Kennedy, Professor of Nursing, UL
Dr Susan Coote, Lecturer in Clinical therapies, UL
Dr Michael Walsh, Biomedical Engineering, UL
Prof Mike Larvin, Head of Graduate Entry Medical School, UL
Dr Mary Clarke Moloney, Clinical Operations Manager, Health Research institute (HRI), UL
Dr Andrew O’Regan, Senior Lecturer, Graduate Entry Medical School, UL
Dr James O’Hare, Consultant Endocrinologist, University Hospital Limerick
Session 1: Oral Presentations
9.50am – 10.50am
Presenting author information
Title
Dr
First name:
Keith Ian
Family name:
Quintyne
Dept. and
Department of Public Health
Organisation
Email:
[email protected]
Presentation title
The changing epidemiology of newly diagnosed HIV infections in Clare, Limerick & Tipperary
North, 2010 to 2014
Co-authors
KI Quintyne1, M Morris-Downes1, B Mooka2, R Fitzgerald1, M Mannix1
1: Department of Public Health, HSE Mid-West, Limerick
2: Department of Infectious Diseases, University Hospital Limerick, Limerick
Oral Presentation Abstract
Introduction:
To study the current epidemiology of newly diagnosed HIV infections in Clare, Limerick &
Tipperary North (HSE MW) and describes the trends over time.
Methods:
Data were collected from 1st January 2010 to 31st December 2014 from enhanced surveillance
records in DPH for HSE MW. A total of 91 cases were identified. A descriptive analysis of
demographic and clinical information was performed.
Results:
In 2014, 18 new cases of HIV were diagnosed in HSE MW, representing a 29% increase
compared with 2010. Between 2010 and 2014, the average age of cases declined from 35
years to 32 years and the male: female ratio remained unchanged. The proportion of cases
born outside of Ireland increased from 21% to 44%. This was associated with an increase in
cases of Black ethnicity from 7% to 17%. MSM transmission was the most common in 2014,
showing an increase from 43% to 67% over the 5 year interval. The median CD4 count
remained unchanged. The median viral load increased from 12012 to 21776 copies/ml. The
proportion of cases presenting asymptomatically decreased from 67% in 2010 to 50% in 2014.
The proportion of cases presenting with co-infections with syphilis and Hepatitis C both
increased (0% to 17% and 0% to 6% respectively), while other STI co-infections patterns
remained unchanged.
Conclusions:
There has been an increase in the annual number of cases of diagnosed HIV infections seen
since 2010. Changes in the epidemiology of newly diagnosed HIV were seen by age, mode of
transmission, country of birth and co-infections with STIs. These changes and increases have
implications for the prevention, planning and financing of HIV services in HSE MW.
Presenting author information
Title
Dr.
First name:
Eileen
Family name:
Humphreys
Dept. and
Institute for the Study of Knowledge in Society
Organisation
Email:
[email protected]
Presentation title
Innovation in health services delivery: Do we need radical innovation to address social
inequalities in access to, and potential to benefits from, health services?
Co-authors
E Humphreys, C Browne, C Garavan
Oral Presentation Abstract
Introduction:
Paper based on evaluation of a programme to improve outcomes for children living in severe
social deprivation. Included interventions in population health and primary care (speech and
language therapy and Public Health Nursing). Programme objectives included innovation,
multi-agency cooperation, user involvement and evidence-based approaches.
Methods:
Applied mixed methods, with an emphasis on a qualitative strategy. Research design involved
theory-based evaluation and a method known as contribution analysis (providing credible
assessments of cause and effect when it is not practical to design experiments to assess
performance). It utilized Participatory Action Research (PAR) approaches with stakeholders
including management and frontline staff. Primary research focused on observation via
participation in meetings and other activities (training, mentoring, service delivery to users).
This involved 107 engagements with services personnel and some clients.
Results:
Capacity building and empowerment of staff can be achieved by working with PAR
approaches. For primary care to achieve better outcomes for children, services need to
engage effectively with parents. Parents from severely socially disadvantaged background are
not health-literate; they lack awareness of the impact they have on their child’s development
including oral language acquisition in early childhood. Improved reach and engagement with
users can be achieved by working in universal services especially schools and crèches. There
are challenges for health services professionals working in community settings linked to
different cultures, professional identities and practice. HSE is perceived negatively; while “rebranding” a service involving users can considerably increase uptake and potential benefits.
Conclusions:
Universal health services involve complex systems not well-suited to meeting needs of socially
disadvantaged populations. Even with access to services free of charge, many do not benefit
from them. Small incremental changes in service delivery can yield promising results and
achieve efficiencies. These involve actions to address structural inequalities and also
behavioral change in the target population. Radical innovation involving higher risks are not
always necessary.
Presenting author information
Title (Dr, Mr, etc)
Miss
First name:
Sandra
Family name:
O’Malley
Dept. and
Surgical Health Outcomes Research Enterprise, Department of Surgery
Organisation
Email:
[email protected]
Presentation title
Significant variation in blood transfusion practice persists following Idiopathic Adolescent
Scoliosis surgery.
Co-authors
Sandra O’Malley, Christopher Aquina, Fergal Fleming, Natasha O’Malley
Oral Presentation Abstract
Introduction:
Perioperative blood transfusions are costly and linked to adverse clinical outcomes. We
investigated the factors associated with variation in blood transfusion utilization following
primary spinal fusion for idiopathic adolescent scoliosis (IAS) and its association with
infectious complications.
Methods:
Data was extracted from the Statewide Planning and Research Cooperative System (SPARCS),
a hospital discharge database for New York State in the United States. Using International
Classification of Diseases (ICD-9), all patients included had a diagnosis of IAS and underwent
spinal fusion from 2000 to 2013. Individual surgeon and facility volume were calculated as the
number of spinal fusions performed per year using the unique surgeon identifier and unique
facility identifier numbers. Bivariate and mixed-effects logistic regression analyses were
performed to assess the factors associated with receiving a perioperative allogeneic red blood
cell transfusion. Additional multivariable analysis examined the relationship between
transfusion and infectious complications.
Results:
Among 6,230 patients who underwent IAS surgery, 27.77 % of patients received a
perioperative blood transfusion. After controlling for patient, surgeon, and hospital-level
factors, significant variation in transfusion rates was present across both surgeons and
hospitals with a 13-fold difference observed in transfusion rates between the lowest and
highest utilization for hospitals and a 4-fold difference observed for
surgeons)(p < 0.0001).Blood transfusion was also independently associated with wound
infection (OR = 2.18, 95% CI = 1.16 and 4.10), and pneumonia (OR = 1.77, 95% CI = 1.24 and
2.51).
Conclusions:
Significant variation in perioperative blood transfusion utilization exists at both the surgeon
and hospital level. These findings are unexplained by patient-level factors and other known
surgeon and hospital characteristics, suggesting that variation is due to provider preferences
and/or lack of standardized transfusion protocols. Implementing institutional transfusion
guidelines is necessary to reduce unwarranted variation and possibly decrease infectious
complication rates.
Presenting author information
Title
Ms
First name:
Geraldine
Family name:
Sheils
Dept. and
Research Assistant, Department of Clinical Therapies, University of
Organisation
Limerick
Email:
[email protected]
Presentation title
We do fun things together: How adults with intellectual disabilities in Ireland navigate
stigma to create lasting friendships
Oral Presentation Abstract
Introduction:
Friendship is a voluntary relationship offering support, loyalty and well-being. For people with
intellectual disabilities, friendship can be interrupted by stigmatizing experiences. This study
sought to understand the dynamics within interpersonal relationships for people with
intellectual disabilities across multiple environments despite experiencing stigma.
Methods:
In depth semi-structured interviews were conducted with eleven people with intellectual
disabilities ranging in age from 20 to 47 years focusing on how they created meaningful
friendships. Interviews were transcribed, cleaned and imported in Atlas.ti qualitative software
for thematic analysis.
Results:
Four themes emerged from the findings: Initiating Friendship, Maintaining Friendship,
Interference on Friendship and Sustaining Friendship. The findings provided a nuanced
understanding of how friendships are strengthened and deepened through mutual trust,
reciprocity, and shared experiences. For many, friendships were sustained through shared
histories and shared social spaces. At times, interference on friendship occurred through
stigmatizing attitudinal barriers, personal conflict and online conflict. However, peer
mentoring and self-advocacy proved viable strategies used by participants to actively disrupt
stigma, and continue with their friendships.
Conclusions:
Protective factors in the form of peer relationships, friendship and peer mentoring can disrupt
stigma and build social connections. The value of these social connections reflects the central
premise of social capital. Occupational therapists are well positioned to afford practical
application of social capital strategies. In particular, peer mentoring and self-advocacy can
assert full community participation for people with intellectual disabilities. In the approach to
Ireland’s ratification of the United Nations Convention of the Rights of Persons with
Disabilities, and the proposed reconfiguration of Irish disability services, it is timely to
strengthen social capital among people with intellectual disabilities to prevent further
isolation and marginalization across their lifespan.
Presenting author information
Title
Mr
First name:
Eoghan
Family name:
Connolly
Dept. and
National Ambulance Service
Organisation
Email:
[email protected]
Presentation title
Assessing the effectiveness of CPR on a manikin with a feedback device
Co-authors
Ms B Sinnott, Dr N Cummins
Oral Presentation Abstract
Introduction:
High quality cardiopulmonary resuscitation (CPR) is a key link in the chain of survival for outof-hospital cardiac arrest (OHCA). Practitioners and responders are required to recertify
regularly in CPR and to deliver this care to critically ill patients thereafter. Time spent on the
chest performing compressions is seen as a critical element for patient survival.
Methods:
The objective of this manikin study was to determine quality of CPR and chest compression
fraction time (CCF) using the TrueCPR feedback device (Physio-Control) in two cohorts; Group
1 (n=35) were Responders as per Pre-hospital Emergency Care Council (PHECC) standards.
Group 2 (n=32) were PHECC Practitioners and other trained Medical Professionals.
Participants performed 4 minutes of CPR and delivered 1 shock via an Automated External
Defibrillator (AED) to a CPR manikin. The TrueCPR device evaluated the compression rate,
depth and chest recoil data producing a percentage of “good” compressions.
Results:
Mean percentage of good compressions for the Responder group was 18% vs. 21% for the
Practitioner group (p=0.55). The practitioner group had better recoil rates and compression
depths than the responders. Chest compression fraction indicated that both groups
performed compressions for 65% of the time allowed. The highest recorded CCF figure was
77% during the trials. During the charge phase for the shock only 13% of practitioners
performed compressions while no responders performed compressions while the AED
charged. TrueCPR also produced time for the longest pause during each test, on average
responders paused for 24 seconds vs. 21 seconds for practitioners (p=0.13).
Conclusions:
Good compression rates were similar between responders and practitioners and do show
room for improvement. As expected practitioners did outperform responders in some key
aspects of CPR. Feedback devices for training and use during OHCA incidents would help guide
all rescuers to maintaining high quality CPR.
Presenting author information
Title
Miss
First name:
Clare
Family name:
Miller
Dept. and
Nephrology Department, University Hospital Limerick
Organisation
Email:
[email protected]
Presentation title
Risk of Acute Coronary Events and Coronary Interventions for Overweight and Obese
patients versus normal weight patients undergoing Dialysis; A National Study
Co-authors
AG Stack, JP Ferguson
Oral Presentation Abstract
Introduction:
In the general population increased body mass index (BMI) has an established deleterious
effect on all cause and CV mortality. An obesity paradox has been uncovered among dialysis
patients, which suggests the converse may hold true. No literature to date has examined the
association between BMI in dialysis patients and acute CV events. Also no research thus far
has analysed the impact of BMI on access to acute coronary interventionsa among dialysis
patients.
Methods:
We tested this hypothesis in a national cohort of 1,028,353 incident US dialysis patients
between 5/1995 to 12/2008. Patients were classified into BMI (kg/m2) categoriesb according
to WHO criteria. Hospitalizations attributed to first myocardial infarction (MI) [ICD 9 codes;
410] and major coronary interventions following first MI were obtained from the US Renal
Data System. Multivariable Cox regression compared [HR] of MI and subsequent coronary
interventions among BMI categories.
Results:
Among both sexes (p=0.15) and all races (except Native Americans) the adjusted HR of MI was
highest for underweight patients [HR 1.03 CI (0.99-1.07)] and lowest among the class III obese
patients [HR 0.84 CI (0.80-0.88)]. Significant heterogeneity was detected between races
groups (p=0.049) with BMI having the greatest effect on risk of MI among black patients.
Following an AMI underweight [HR 0.90 CI (0.81-1.01)] and class III obese patients [HR 0.93 CI
(0.84-1.02)] were significantly less likely to receive a major coronary intervention compared to
the intervening overweight [HR 1.17 CI (1.11-1.24)] and class I obese [HR 1.08 CI (1.02 -1.16)]
BMI categories.
Conclusions:
In contrast to the general population higher BMI is associated with lower risk of MI in US
dialysis patients. This effect is especially significant in Black patients. Furthermore White,
Black and Native-Americans at both extremes of weight are experiencing reduced rates of
major coronary interventions post MI suggesting access to coronary interventions is not equal
across BMI categories.
A
Coronary Interventions: Percutaneous coronary intervention, Angioplasty, Coronary artery bypass
graft
B
BMI categories: underweight (BMI < 18.5 Kg/m2), normal weight (BMI 18.5-24.9 kg/m2), overweight
(BMI 25-29.9 kg/m2), obesity-class 1 (BMI 30-34.9 kg/m2), class 2 (BMI 35-> 39.9 kg/m2) and class 3
(BMI>40kg/m2)
Session 2: Oral Presentations
1.00pm – 2.00pm
Presenting author information
Title
Dr.
First name:
Debbie
Family name:
White
Dept. and
Department of Anaesthetics, University Hospital Galway
Organisation
Email:
[email protected]
Presentation title
Development of a Novel Test of Visuospatial Cognition: The Letter and Shape Drawing Test.
A study of performance in Hospitalised Elderly Patients and Young Healthy Adults
Co-authors
OA Williams, M Leonard, C Exton, D Adamis, A Hannigan, CP Dunne, D Meagher
Oral Presentation Abstract
Introduction:
Conventional bedside tests of visuospatial function such as the Clock Drawing (CDT) and
Intersecting Pentagons (IPT) are subject to considerable inconsistency in their delivery and
interpretation. We compared the use of a novel test - the Letter and Shape Drawing Test
(LSD) – with these conventional tests in cognitively intact young persons and hospitalised
elderly patients.
Methods:
Performance on the LSD, IPT, CDT and the Montreal Cognitive Assessment (MoCA) was
assessed in 80 participants; 40 acutely unwell elderly (aged >=65) medical inpatients at
University Hospital Limerick and 40 final year medical students.
Results:
The elderly medical patients had a median MoCA score of 15.5 (SD: Range = 1 to 29) as
compared with 26.7 (Range = 23 to 30) for the medical students. For the elderly patients,
there was a strong, positive correlation between both the LSD and the CDT (r=0.56) and IPT
(r=0.71). The correlation between the LSD and MoCA (r= 0.91) was greater than for the CDT
and IPT (both 0.67). The LSD correlated highly with all MoCA domains (ranging from 0.540.86) and especially for the domains of orientation (r=0.86), attention (0.81) and visuospatial
function (r=0.73). Two or more errors on the LSD identified 90% (26/29) of those patients
with MoCA scores of ≤ 20 which was substantially higher than for the CDT (59%) and IP (55%).
Conclusions:
The LSD is a novel test of visuospatial function that is brief, readily administered and easily
interpreted. Performance on this test correlates strongly with other tests of visuospatial
ability and these preliminary findings suggest favourable ability to identify patients with
significant impairment of general cognition.
Presenting author information
Title
Ms
First name:
Marie
Family name:
Keays
Dept. and
Stokes Laboratories, University of Limerick
Organisation
Email:
[email protected]
Presentation title
A Microfluidic Platform for analysis of treatment of Breast Cancer and the Identification of
Antibiotic Resistance in Bacterial Cultures
Co-authors
T. Dalton and P.A.Kiely
Oral Presentation Abstract
Introduction:
Cell culture methods provide an initial step when understanding a disease. They provide
information that can give genetic identification of disease that can aid in the diagnosis and for
an effective treatment. However, the methods that are used for these cultures have changed
very little since there first establishment. Cell culture methods rely on consumable plastic
ware and valuable personnel time to perform these methods. The generation of a microfluidic
droplets provides a method that can reduce the size of these cultures to under 1ul but also
increase the throughput through automation. This research will demonstrate how microfluidic
droplet cell culture is a robust environment for cell proliferation.This facilitates the
establishment of a set of parameters that lie closer to in-vivo conditions
Methods:
Design and prototyping of a microfluidic droplet platform for the generation of droplet cell
cultures of 500nl-1000nl in volume. As each droplet acts as a single bioreactor, this will
enable individual three-dimensional cancer models be tested against a specific treatment. This
system has also developed bacterial models for the identification of effective treatment or
antibiotic resistance to drugs.
Results:
A nano-litre scale breast cancer model has been developed and treated successfully providing
a genetic profile that compares to current methods . This breast cancer model is 600nl in
volume compared to a culture flask of 10ml. E.coli cultures have been developed in the
microfluidic droplets and the identification of antibiotic resistance as well as an effective
treatment were completed in four hours in an automated process.
Conclusions:
The instrument developed here identified treatments for bacterial and mammalian cell
models. The culture droplets are created in a nano-litre range and multiple unique bioreactor
droplets can be prepared and analysed on one system making this a time and cost effective
instrument.
Presenting author information
Title
Mr.
First name:
Christopher
Family name:
Hayes
Dept. and
Stokes Laboratories, University of Limerick
Organisation
Email:
[email protected]
Presentation title
Identification of Genetic Biomarkers for Metastatic Colorectal Cancer
Co-authors
CM Dowling, C Hannan, JC Coffey, PA Kiely, TM Dalton
Oral Presentation Abstract
Introduction:
In patients who have been diagnosed with cancer, biomarkers have many potential
applications including differential diagnosis, prediction of response to treatment and
monitoring of progression of disease. To identify potential biomarkers, large scale gene
expression profiling is an essential tool for the biological investigations of pathological
samples. However, this approach is often limited by the availability of large amounts of
biological sample for RNA extraction.
Methods:
From an engineering perspective, we are using continuous-flow microfluidic droplets which
act as distinct miniature reactors to quantify gene expression levels of both normal and cancer
samples taken from a patient cohort. Microfluidics provides numerous advantages for this
application including economies of scale, parallelisation and increased sensitivity that come
from nanolitre reactions. From a biological standpoint, our focus is on genes (n=34 in our
study) that are regulating extracellular matrices (ECM) which are central components of a
tumour’s microenvironment. ECM dysregulation contributes to the transformed phenotype by
providing specific environmental cues that alter cell behaviour and increase the metastatic
potential of cancer cells.
Results:
In a small patient cohort (n=24) of matched benign, stage I, II, III, and documented metastatic
samples, a pattern of differentially expressed ECM associated genes has emerged between
tumour-associated normal and diseased tissue of the same patient. Integrin & matrix
metalloproteinase (MMP) families are among those most dysregulated in the patient samples
analysed.
Conclusions:
Expanding this profile may help separate colorectal cancer into distinct ‘extracellular matrix
protein expressing’ groups from which we will be able to develop robust diagnostic and
prognostic tools that can be applied in a clinical setting. Furthermore, significant associations
of gene expression levels and clinicopathological variables such as tumour size, grade, invasion
and lymph node status may be identified.
Presenting author information
Title
Dr
First name:
Noel
Family name:
Carroll
Dept. and
ARCH - Applied Research for Connected Health Technology Centre, Department
Organisation
of Computer Science & Information Systems, University of Limerick
Email:
[email protected]
Presentation title
Employing a Software Quality Plan within a Distributed Team Environment
Co-authors
I Richardson
Oral Presentation Abstract
Introduction: TRANSFoRm, an EU-funded FP7 project, proposed to develop a ‘rapid learning healthcare
system’ driven by advanced computational infrastructure that would improve both patient safety and the
conduct and volume of clinical research in Europe. To achieve this, software development was required. In
order to support the software development process, a TRANSFoRm Software Quality Plan played a critical
role. The TRANSFoRm Software Quality Plan combined healthcare regulations with software regulations
which the distributed team had to comply with throughout the project development.
Methods: Building on the TRANSFoRm Software Quality Plan we examined how it supported the TRANSFoRm
software developers to build in a level of quality into their tools. The various stages of the plan were devised
based on published software processes and Medical Device Regulations. We revisit this Software Quality Plan
with the aim of reviewing how it was implemented, how it contributed towards the success of the
TRANSFoRm project and whether there are any valuable ‘lessons learned’ from the healthcare technology
project. Specifically, we interview the development teams located in the UK, Ireland and Poland which
constitute as key members of the distributed project team. With a view to understand how software
standards can support medical device regulation, we surveyed the TRANSFoRm Work Task team using the
Software Quality Plan to examine how they implemented the plan to successfully meet the projects aim and
objectives.
Results: We uncovered the complexities and challenges to establish a developer community that align
healthcare requirements and software development processes with other stakeholders. Common challenges
include introducing new partners to one another and developing new working relationships, vocabulary used
in healthcare and computer science domains, exploratory nature of research, politics between working
groups, decision-making and empowerment, visibility and transparency of activities, impact of development
on other tasks. Going forward with other large health technology EU projects, establishing project
management and collaboration structures will play a significant role in the success of distributed software
development projects. The Software Quality Plan proved to be a critical resource. Of particular importance is
the need for the inclusion of a Work Package to Set up the Software Development Strategy and Management
Policy when proposing future EU healthcare technology projects, such as Horizon 2020.
Conclusions: The TRANSFoRm was an exciting project to enhance patient safety and the conduct clinical
research in Europe. Our findings also indicate that additional emphasis must be placed on strategy, not
technology, at the beginning of a distributed software project since this ultimately drives the digital
transformation and ensures that technical milestones are met. Our results also indicate that the Software
Quality Assurance Framework proved to be a core resource for the TRANSFoRm project providing a common
goal and vocabulary for all of the TRANSFoRm team to focus on throughout the software development
process. Through the use of the Software Quality Plan, TRANSFoRm could successfully meet the project
objectives and maintain a high quality of standard in capturing clinical data, achieve a distributed
interoperability of data and developed unique software tools and healthcare services.
Presenting author information
Title
Ms.
First name:
Sylvia. M
Family name:
Murphy
Dept. and
Department of Life Sciences
Organisation
University of Limerick
Email:
[email protected]
Presentation title
An in vitro bioassay to study the bioactivities of nutrient compounds for hypertrophy and/or
recovery of skeletal muscle
Co-authors
M Kiely, P Jakeman, P.A. Kiely and B.P Carson
Oral Presentation Abstract
Introduction:
The regulation of muscle protein metabolism to maintain or augment lean tissue mass (LTM)
is of primary importance to athletes and healthy ageing cohorts alike. Identifying nutrient
regulators of muscle protein metabolism to support recovery from and maintenance of
healthy muscle is of particular interest. The aim of this investigation was to develop a novel in
vitro cell-based electric impedance assay to study nutrient regulation of muscle cell
hypertrophy and recovery.
Methods:
C2C12 skeletal muscle myoblasts were proliferated until 70% confluent in DMEM (10% FBS)
and subsequently differentiated to myotubes over 8 days in DMEM (2% HS) on a Real Time
Cell Analysis (RTCA) platform (xCELLigence™, ACEA). Changes in cell behavior and adhesion
properties were monitored by measuring impedance via interdigitated microelectrodes in the
base of cell culture dishes. To monitor nutrient regulation of muscle hypertrophy, C2C12
skeletal muscle myotubes were incubated in physiologically relevant concentrations of leucine
(0.20, 0.40, 0.6, 0.8mM), a known potent regulator of MPS and continuously monitored on
RTCA. To assess muscle recovery, C2C12 skeletal muscle myotubes were subject to
dexamethasone (20uM), a known atrophic agent, followed by ‘recovery’ of C2C12 myotubes
in amino acid free media supplemented with leucine.
Results:
We have developed a robust real-time bioassay to study muscle myotube formation and
maintenance. Using this novel assay, we show a dose response hypertrophic and recovery
effect of leucine (Hypertrophy: Con 100%, 0.2mM Leu 96.6%, 0.4mM Leu 111.9% and 0.8mM
120.6%; Recovery: Con 100%, 2mM Leu 125.6%) on C2C12 myotubes by RTCA. These findings
are supported by alterations in MPS (mTOR, P70S6K, 4EBP1, P-MAPK) signaling pathways.
Conclusions:
This in vitro bioassay can be used to identify nutrients compounds with bioactivities for
skeletal muscle hypertrophy and recovery and thus inform the development of novel nutrient
formulations.
Presenting author information
Title
Dr.
First name:
Finola
Family name:
Cliffe
Dept. and
Stokes Laboratories, Department of Mechanical, Aeronautical and
Organisation
Biomedical Engineering
Email:
[email protected]
Presentation title
High throughput screening for combinational drug discovery
Co-authors
M Davies, M Galvin, E O’Shea
Oral Presentation Abstract
Introduction:
ENIGMA is a high throughput screening platform with a focus on the screening of therapeutic
drugs, specifically in the area of combination drug discovery. This microfluidic system delivers
a low cost, automated, contamination-free and versatile instrument. Currently the
pharmaceutical industry is facing long lead times and high development costs. ENIGMA can
address these problems by accelerating drug discovery whereby millions of drug compounds
can be rapidly screened to generate hits. Generating new synergistic combinations of existing
drugs offers a relatively low cost way of bringing new drugs to market.
Methods:
Several prototype builds of ENIGMA have been completed and are ongoing. Each prototype
was carefully designed, built and tested for accuracy and reproducibility. Each drug
combination was assayed against whole cells to assess viability via fluorescent detection.
Synergistic combinations of FDA approved off-patent drugs were determined based upon
ability to kill cells or inhibit cell growth.
Results:
A series of prototypes have been designed, built and tested with the current prototype
equipped to hold 8 wells. Many positive outcomes in flowing droplets have been
demonstrated
Proved viability of various cell types such as mammalian (MCF7, induced pluripotent stem
(iPS) cells) and bacterial (pathogenic and non-pathogenic E. coli)
Successful segmentation and mixing of cells and drugs from separate wells
Effective drug action on bacterial and mammalian cells
Many more encouraging results have been generated from offline experiments
Conclusions:
It is expected that the final ENIGMA prototype will hold 300 samples and can accommodate
combinations of 3 resulting in 4.5 million data points within a 5 day period. It is also
anticipated that patient derived iPS cells (disease differentiated) will be employed as disease
models for screening of therapeutic drug combinations once the instrument is fully validated.
ENIGMA holds the potential to advance research within the healthcare sector.
Session 3: Oral Presentations
3.10pm – 4.10pm
Presenting author information
Title
Mr
First name:
David
Family name:
Lynch
Dept. and
Organisation
University of Limerick Graduate Entry Medical School
Department of Surgery UHL, Mid-Western Cancer Centre UHL,
Department Radiation Oncology UHL
Email:
[email protected]
Presentation title
Management of a positive sentinel lymph node at University Hospital Limerick– Oncological
patterns of care
Co-authors
C Baban, L Coate, A Lal, S Tormey, A Merrigan, A Hannigan, B Woulfe, L Walsh
Oral Presentation Abstract
Introduction:
To determine how patients with early stage breast cancer and a positive sentinel lymph node
(SLN+ve) are further managed at our institution (surgically, systemically, radiotherapeutically)
and to determine the factors which influence the approach taken, comparing it to ACOSOG
Z0011.
Methods:
Data was collected on all SLN biopsy procedures conducted between Jan 2010 – July 2014
(n=375) and validated with surgery lists, individual pathology reports, patient charts and
electronic records. Graph pad (Chi squared, Fisher's exact test, Chi squared for trend and
independence) was used for data analysis.
Results:
101 patients had SLN+ve - 62(61%) underwent axillary lymph node dissection (ALND), 39
(39%) had no further axillary surgery (SLNB alone).
Factors which impacted the decision to proceed with ALND were a macrometastically SLN+ve
(p=0.005), number of SLN+ve (p=0.0029), grade and receptor status (p=0.01). Chemotherapy
was given more frequently in the ALND group (p=0.003). In contrast to ACOSOG Z0011,
locoregional radiation was given more frequently in both groups, particularly when ALND had
been performed (p=0.016).
Conclusions:
The surgical impact of ACOSOG Z0011 is evident at out institution with 39% of patients who
previously would have been considered for ALND receiving SLNB only. Its impact on selection
of adjuvant therapy (chemo & radiotherapy) is not apparent, with patients receiving less
chemo but more extensive locoregional radiation when compared with the SLNB group of
Z0011. Clinical guidelines being developed by the Irish National Cancer Control Programme,
have identified this often challenging issue and will be welcome in standardising practice.
Presenting author information
Title
Mr
First name:
Zeshan
Family name:
Siddiqui
Dept. and
Y4 Medicine, GEMS UL
Organisation
Email:
[email protected]
Presentation title
Glycaemic Control Is Comparable In Patients With Or Without Significant Hepatic Fibrosis As
Assessed By NAFLD Fibrosis Score
Co-authors
Chin JL, Chan G, Sin PS, Siddiqui Z, O’Rathallaigh E, Aftab A, Courtney G, McGurk C
Oral Presentation Abstract
Introduction:
Non-alcohol fatty liver disease (NAFLD) is increasingly recognised in diabetic patients with
metabolic syndrome. Patients with poorly controlled diabetes and the metabolic syndrome
are likely to have significant liver inflammation leading to fibrosis. NAFLD fibrosis score (NFS) is
a validated non-invasive scoring system that identifies liver fibrosis in patients with NAFLD.
The aim of this study is to examine the glycaemic control in patients with or without
significant hepatic fibrosis as assessed by NFS in the routine diabetic clinic.
Methods:
All patients with type 2 diabetes or impaired glucose tolerance/fasting glucose, attending the
diabetic clinic from March to June 2014 were included retrospectively. Patients with type 1
diabetes and gestational diabetes were excluded. Data were obtained from laboratory
database and electronic patient record (Cellma). NFS was calculated for each patient based on
age, BMI, diabetes, AST/ALT, platelet and albumin.
Results:
521 patients were screened and only 29.4%(153) of patients with complete laboratory data
were studied. In our cohort of 153 patients, 64.1%(98) of patients were male and the median
age was 63(IQR 56.0–71.5) years. Using the NAFLD fibrosis score, almost a quarter of our
patients (24.2%, n=37) had significant fibrosis with a median score of 1.169(0.898–1.563)
while the rest of the patients were indeterminate (66.0%, n=101) or had no significant fibrosis
(9.8%, n=15). The median BMI for patients with significant hepatic fibrosis was 30.0(27.8–
34.5)kg/m2 while for patients without significant fibrosis (including indeterminate score based
on NFS), the median BMI was 34.8(30.3-43.2)kg/m2 (p<0.01). Interestingly, there were no
significant differences in the mean HbA1c readings in patients with or without significant
hepatic fibrosis (55.2±15.3mmol/mol versus 56.6±17.9mmol/mol; p=0.639).
Conclusions:
In conclusion, we did not observe any significant differences in glycaemic control in patients
with or without significant hepatic fibrosis, as assessed by NAFLD fibrosis score in clinic.
Presenting author information
Title
Ms
First name:
Arlene
Family name:
Weir
Dept. and
Graduate Entry Medical School, University of Limerick.
Organisation
Email:
[email protected]
Presentation title
A review of thyroid sonographic features and international guidelines; ability to
differentiate benign and malignant nodules
Co-authors
Dr. Declan Sheppard
Oral Presentation Abstract
Introduction:
The aim of this study was to review six sets of internationally accepted thyroid fine needle
aspiration guidelines and to assess their accuracy and to examine local adherence to these
guidelines. The guidelines used were those created by the American Thyroid Association, the
British Thyroid Association, the Korean Society of Thyroid Radiology, the American Society of
Radiologists in Ultrasound, Kim Criteria and a combined guideline from the American
Association of Clinical Endocrinologists, Associazione Medici Endocrinologi and European
Thyroid Association.
Methods:
A total of 100 thyroid nodules that were diagnosed on ultrasound and subsequently
underwent fine needle aspiration cytology were included in this study. The sonographic
features of each nodule were examined and the compared with the final cytology and
histology reports. The sonographic features were then compared to six sets of thyroid FNA
guidelines and their sensitivity, specificity, positive predictive values and negative predictive
values were calculated. Adherence to the guidelines was also reviewed. These results were
then compared to a similar study of a larger scale.
Results:
Of the ultrasound features associated with each type of nodule, a cystic/spongiform
consistency was found to have a high specificity (91.7%) for benign nodules, with
microcalcifications (91.8%) being the most specific for thyroid cancer. There was found to be a
greater adherence to more established guidelines. However, this review took place prior to
the introduction of the new BTA guidelines (2014), which in our study had the highest
combined sensitivity (83.3%) and specificity (67.4%). Retrospective adherence to the BTA
guidelines shows that they would have missed only one Thy 5 cancer.
Conclusions:
All guidelines provide a minimum clinical standard, which is of most benefit to inexperienced
operators. For more experienced clinicians, the addition of subjective experience to the new
BTA guidelines may provide the highest accuracy.
Presenting author information
Title
Dr
First name:
Shahzaib
Family name:
Saleem
Dept. and
University Hospital Limerick – Dept of Respiratory Medicine
Organisation
Email:
[email protected]
Presentation title
Usefulness of Ultrasound in Evaluating the Recovery of Diaphragm Paralysis
Co-authors
Hynes, TS., Saleem, S., Casserly, B
Oral Presentation Abstract
Introduction:
Ultrasound has been proven to be a non-invasive method of diagnosing diaphragm paralysis.
However its usefulness in monitoring the progress of diaphragm recovery has not been fully
delineated. Therefore we evaluated the usefulness of measurements of diaphragm thickness
(dT) and diaphragm thickening during inspiration (iDT) in assessing functional recovery of
paralyzed diaphragms.
Methods:
Sixteen patients diagnosed with diaphragmatic paralysis were followed for a period of 60
months. During which they underwent serial ultrasound measurements of diaphragmatic
thickness and its change with inspiration. These measurements were compared with vital
capacity (VC), maximal inspiratory (maxIP) and expiratory (maxEP) pressures.
Results:
Of the 16 subjects, 11 regained fully functional diaphragms. The mean recovery time for the
11 patients was 14.9 month (±6.1). Diaphragms that recovered showed significant increase in
both thicknesses from time of paralysis (30.4 ±24.5% vs -1.6±15.5% - P<0.001) and inspiratory
diaphragm thickening (40.6 ±17.9% vs 1.8±8.0% P<0.05) compared to those that did not.
Additionally change in diaphragm thickness was shown to significantly correlate with the
change in VC (R2=0.44 P=0.005).
Conclusions:
Therefore ultrasound shows promise as a useful tool to evaluate the recovery process of
patients suffering from a paralyzed diaphragm and should receive further consideration and
appraisal in this role.
Presenting author information
Title
Dr
First name:
Ronstan
Family name:
Lobo
Dept. and
Department of Cardiology, University Hospital Limerick
Organisation
Email:
[email protected]
Presentation title
High sensitive troponin t levels following elective external direct current cardioversion for
atrial fibrillation and atrial flutter
Co-authors
C Cahill, O Blake, S Abbas, TB Meany, T Hennessy, TJ Kiernan
Oral Presentation Abstract
Introduction: External transthoracic direct current (DC) cardioversion is a commonly used
method of terminating arrhythmias, emergently or electively. It is known that external DC
cardioversion can result in a rise in creatine kinase (CK). Previous research has shown that DC
cardioversion resulted in subtle myocardial injury as evidenced by CK-MB, troponin I and
troponin T increase, even though only minimally. These studies were based on the outdated
monophasic defibrillators and older troponin assays. Since early 2010, the new high sensitive
troponin T (Hs-trop T) assays have been used to diagnose myocardial injury and have been found
to be highly sensitive and specific. This study aimed to assess the effect of external transthoracic
DC cardioversion on myocardial injury as measured by the change in Hs-trop T using the more
modern biphasic defibrillators in an elective setting.
Methods: Patients who were admitted for a day-case elective DC cardioversion for atrial
fibrillation or atrial flutter were asked to participate in the study. DC cardioversion was
performed using the Phillips Heartstart XL biphasic defibrillator. For cardioversions that failed at
200 Joules, the Physio-Control Lifepak 20e 360 J biphasic defibrillator was used. Hs-trop T levels
were taken pre-cardioversion and at 6 hours post-cardioversion (in keeping with the Third
Universal Definition of Myocardial Infarction guidelines on biomarker detection of myocardial
injury with necrosis). The assay used was the Roche Elecsys Troponin T hs (high sensitive)
immunoassay. Quantitative analysis for haemolysis, icterus and lipaemia (which could result in
interference with the Hs-trop T assay) were measured in each blood sample that was taken using
the Abbott Architect c16000.
Results: A total of 120 cardioversions were done on 101 patients. Analysis of each of the blood
sample taken showed no raised haemolytic, icteric or lipaemic indices above the
recommendations for the Hs-trop T assay. Median number of shocks was 1, and the maximum
number of shocks was 6. Median cumulative energy was 150 Joules (interquartile range = 387.5
Joules) with the minimum being 50 Joules and maximum being 1730 Joules. A total of 49 (40.8%)
patients received a cumulative defibrillation energy of 300 Joules or higher. The highest energy
delivered per shock was 360 Joules and median peak impedance levels was 80.80 Ohms
(interquartile range = 19.05 Ohms). Median Hs-trop T levels pre-cardioversion was 7 ng/L
(interquartile range = 7) and post-cardioversion was 7 ng/L (interquartile range = 6). A Wilcoxon
signed-rank test showed no significant difference between pre-and-post cardioversion Hs-Trop T
levels (Z = -0.940, p = 0.347).
Conclusions: External DC cardioversion did not result in myocardial injury as measured by high
sensitive troponin T. The implications of this study is important as patients who are cardioverted
and are found to have a significant troponin rise post-cardioversion should be assessed for
causes of myocardial injury and not assumed to have myocardial injury due to the cardioversion
itself.
Presenting author information
Title
Mr
First name:
Bradley
Family name:
Taylor
Dept. and
University of Limerick – Graduate Entry Medical School
Organisation
Email:
[email protected]
Presentation title
Public health benefits of commuter cycling in urban environments – infrastructure
modification and bike-share for facilitating mode shift
Co-authors
Taylor B1, Nathan Y1
1
University of Limerick Graduate Entry Medical School, Limerick, Ireland
Oral Presentation Abstract
Introduction:
Positive public health outcomes due to increased levels of physical activity are well
documented in the literature. This review seeks to present evidence from existing research
regarding both positive and negative health outcomes due specifically to cycling and health
outcomes associated with promoting mode shift from private car use to cycling as a means of
daily commute. Further, a review is conducted of built environmental factors that promote an
effective urban cycling program within a community, and specifically examines research into
bike-share as an effective means of promoting commuter cycling within an urban community.
Methods:
Non-systematic review of the literature uncovered a total of 51 papers (26 health outcomes,
20 built environmental factors, 5 bike-share) that met inclusion criteria of which a great many
were cross-sectional or observational studies. Ethical approval was not needed for this review.
Results:
Greater benefits than harms were seen with relative risk 0.5-0.9 for decreased chronic disease
risk, 0.993-1.020 for road traffic accidents, and 1.001-1.053 for inhalational exposure. Specific
factors found to be positively correlated to increased cycling are spatial accessibility to green
spaces and proximity facilities as well as the availability of cycle paths. Bike-share usage
increases with proximity to docking station whereby those living within 250m of a docking
station are 2.4 times as likely to cycle.
Conclusions:
Bike-share systems are good promoters of commuter cycling in many jurisdictions where the
following features are positively correlated with their effectiveness: percent coverage of each
of major landmarks, schools, places of business, transportation hubs, and total metropolitan
area. It is recommended that station density be between 4-7 stations/km-1 for older intelligent
station designs, but may be less for intelligent-bike designs. This is to limit the distance that
one needs to walk in order to access the network which is of itself, a strong deterrent to public
bike share.
Poster Presentations
POSTER PRESENTATION: HEALTH SERVICES & POPULATION HEALTH RESEARCH
ID
Presentation Title
A01
Dr
Environmental determinants and
distribution of verotoxigenic Escherichia
coli (VTEC) infection in Ireland, 2008–2013 –
a geostatistical investigation
Dr
Management Of New Onset Atrial
Fibrillation in Stable Patients
Jean
Evaluation of the quality of GP referrals to a Dr
mental health outpatient service in
Limerick City.
Dr
A Follow-Up Audit of the Adult Midwest
Mental Health Assessment form 2015
A03
A04
A05
A06
A07
A08
A09
A10
A11
A12
A14
Title
Author
Category
Dept /Org
Health Services &
Population Health
Research
Dept of Life Sciences, UL
Mohamed Ahmed
A
Health Services &
Population Health
Research
Cardiology Dept
UHL
Dr.Catherine
McGorrian
Joyce
Leader
Health Services &
Population Health
Research
Dept of Psychiatry, UHL
S. Winkel
KIRAN
BUDREE
Health Services &
Population Health
Research
PSYCHIATRY ACUTE UNIT
Dr Sheila
Tighe
Lymph node ratio (LNR) in sentinel lymph Dr Keith Ian
node biopsy (SLNB) era: are we losing
prognostic information?
Ms Cliodhna
Change in Model of Care and
Accommodation in a High Dependency Unit:
a Comparison
Prof Pierce
A report of the state of the hospitals in
Ireland in the 18th century
Quintyne
Health Services &
Population Health
Research
Dept of Public Health
KI Quintyne
Ashe
Health Services &
Population Health
Research
Medical Student, UL
J. O’Dea
Grace
Health Services &
Population Health
Research
Dept of Surgery
GEMS, UL
It's my problem I’ll handle it: A mixed
method exploration of psychological
distress and help seeking amongst higher
education students
Characterising self-weighing in a population
of Irish general practice patients: a cross
sectional study
Hydroxychloroquine Cardiomyopathy: Case
report and literature review, a rare disease
or overlooked diagnosis.
Audit of the use of acute hospital beds at
Midlands Regional Hospital Tullamore using
The Appropriateness Evaluation Protocol
(AEP).
An evaluation of the experiences of
students, community group facilitators &
service users who participated with nontraditional physiotherapy student
placements
Christine
Deasy
Health Services &
Population Health
Research
Dept of Nursing and
Midwifery, UL
Mr
Michael
Crickmer
Health Services &
Population Health
Research
Dr
Mohamed Ahmed
Ms
Ceire
Ms
Anne
O'Dwyer
Co-Author 1 Co-Author Co-Author 3 Co-Author 4 Co-Author
2
5
C
P Hynds
M Morris
C Adley.
ÓhAiseadha
Downes
Y. Mushtaq
B Woulfe
JC Coffey
RK Gupta
B Coughlan
D Jourdan
J Pironom
P MannixMcNamara
UL Medical Student
Mr. Michael
Johnson
Dr. Eamonn Dr. Brendan
Shanahan O’Shea
Health Services &
Population Health
Research
Cardiology Dept, UHL
Dr.S Donnelly Dr.A.Fabre
McGuane
Health Services &
Population Health
Research
GEMS Limerick
S. Murray
O Connor
Health Services &
Population Health
Research
Clinical Therapies Dept, M O’Donnell
UL
Co-Author
6
Co-Author
7
Co-Author
8
Co-Author
9
Co-Author
10
POSTER PRESENTATION: HEALTH SERVICES & POPULATION HEALTH RESEARCH (continued)
ID
Presentation Title
A15
Audit: Antibiotic prescribing in primary care
A16
What lies beneath: right ventricular paced
rhythm with underlying inferior STEMI and
paroxysmal atrial fibrillation.
‘This-ability’: Anti-stigma initiatives from
the perspective of people living with
mental illness
Multidisciplinary Primary Care Teams in
International Settings: A review of
International Policy
Prognostic importance of Urea and
Urea/Creatinine ratio for mortality as
compared to Creatinine concentrations in
the General Population
Analysis of exercise capacity and health
related quality of life in patients two years
after completion of a Pulmonary
Rehabilitation Programme
Case report A thrombus in transit through
patent foramen ovale with underlying
silent DVT and pulmonary embolism.
AUDIT of Pain Management in the
Emergency Department of University
Hospital, Limerick.
Common Variable Immunodeficiency – A
Master of Disguise for Sarcoidosis?
RISK OF ISCHAEMIC STROKE FOR INCIDENT
PATIENTS TREATED WITH PERITONEAL
DIALYSIS VERSUS HAEMODIALYSIS
Mineral Bone Disease Management in nondialysis Chronic Kidney Disease: Findings
from an Irish CKD Survey
A17
A18
A19
A21
A22
A23
A24
A25
A26
Title
Author
Category
Dept /Org
Co-Author 1 Co-Author
2
Graduate Entry Medicine, Dr Jim Ryan Dr Julie
UL
McMahon
Cardiology Dept, UHL
Prof.Kiernan V.Voon
Dearbhla
Byrne
Dr
Khalid
Mostafa
Ahmed
Ms
Michelle
McCann
Health Services &
Population Health
Research
Dept of Occupational
Therapy, UL
Dr. N Salmon
Miss Rachael
King
Health Services &
Population Health
Research
GEMS, Faculty of
Education and Health
Sciences, UL
R. King
E. Tierney
Mr
Ronan
Cusack
Health Services &
Population Health
Research
GEMS, UL
J Ferguson
AG Stack
Brian
Fitzgibbon Health Services &
Physiotherapy UHL,
Nenagh
O Quinn
Dr B
Casserly
Cardiology Dept, St
Vincent’s University
Hospital
Prof.D.Keane M.Quinn
Health Services &
Population Health
Health Services &
Population Health
Research
Population Health
Research
Dr
Khalid
Mostafa
Ahmed
Health Services &
Population Health
Research
Miss Katarzyna Domanska Health Services &
Co-Author 3 Co-Author 4 Co-Author
5
Dr Emma
Dr Sannah
O’Keeffe
Sithole
A.Abbas
U.Azhar
M. Ayyaz
Co-Author
6
M. O’Sullivan A.
MacFarlane
Dr A O Brien F Steed
S.Mubarak
F. Masood
GEMS Limerick
Population Health
Research
DR
WAN LIN
WAN LIN
Dr
Mohamed Elsayed
Dr
Muhamma Sharif
d
Health Services &
Population Health
Research
Health Services &
Population Health
Research
Dept of Respiratory
Medicine
AD O’Brien
Nephrology Dept – UHL
J P Ferguson MU Sharif
Health Services &
Population Health
Research
Nephrology Dept-UHL
M Elsayed
MC Moloney A G Stack
J Ferguson A Mutwali
C Cronin
L Casserly
A Stack
Co-Author
7
Co-Author
8
Co-Author
9
Co-Author
10
POSTER PRESENTATION: HEALTH SERVICES & POPULATION HEALTH RESEARCH (continued)
ID
Presentation Title
A27
An Audit on Medication Reconciliation in a Dr
Tertiary Care Hospital
Dr
NEVER UNDER DIAGNOSE DELIRIUM! AN
AUDIT OF ASSESSMENT OF COGNITION ON
ADMISSION OF CONFUSED PATIENTS
Dr
Novel Methods for Record Linkage in the
Irish Health System: Applications to linking
Laboratory and Mortality records
Dr
Long-Term Consequences Of Transient
Acute Kidney Injury On Risk Of Death And
Kidney Failure In The Irish Health System.
Dr
PRACTICE PATTERNS IN BLOOD PRESSURE
MANAGEMENT AND TARGETS AMONG NONDIALYSIS CHRONIC KIDNEY DISEASE
PATIENTS: RESULTS OF A MULTI-CENTRE
AUDIT AND NATIONAL SURVEY.
Improving Quality of Care for Acute Kidney Dr
Injury in the Irish Health System
Dr
Enhancing alcohol screening and brief
intervention among people receiving
opioid agonist treatment: Qualitative study
in primary care.
Ms
Screening and brief intervention for
problem alcohol use among a high-risk
group in primary care: Feasibility study of a
complex intervention among people who
use drugs
MS
Using effective documentation style for
dietetic consultations in the management
of Gestational Diabetes Mellitus
‘Challenges in Accessing and Interviewing Mr
Participants with Severe Mental Illness’
Risk Assessment and Management of
Osteoporosis in Females over 65 years at
Slaney Medical Centre, Enniscorthy, Co.
Wexford
A28
A29
A30
A31
A32
A33
A34
A35
A36
A37
Title
Author
Category
Dept /Org
Co-Author 1 Co-Author Co-Author 3 Co-Author 4 Co-Author
2
5
C.B. Sabu
V. Pradeep N. Muthalvan
Kowshika Thavarajah Health Services &
Population Health
Geriatric Medicine,
UHL Kowshika Thavarajah Health Services &
Population Health
Geriatric Medicine,
UHL N.
Muthalvan
A. Gabr
V. Pradeep
John
Ferguson
Health Services &
Population Health
Research
GEMS
A Hannigan
M Sharif
A Stack
John
ferguson
Health Services &
Population Health
Research
GEMS
M Elsayed
M Sharif
Mohamme Kaballo
d
Health Services &
Population Health
Research
Division of Nephrology,
Dept of Medicine, UHL
MA Kaballo
Mohamme Kaballo
d
Health Services &
Population Health
Research
Health Services &
Population Health
Research
Division of Nephrology,
Dept of Medicine, UHL
Research
Research
Co-Author
6
Co-Author
7
Co-Author
8
D. Lyons
M.O'
Connor
H Johnson
P Murray
A Stack
MU Sharif
K Hanley
ME Elsayed
L Ryan
A Hannigan LF Casserly CJ Cronin
MA Kaballo
JZ Qazi
GS Ahmed
ME Elsayed
MU Sharif
LF Casserly MM
GAFFNEY
GEMS, UL
G McCombe
AM
Henihan
J Klimas
D Swan
D Leahy
W Cullen
R. Anderson G. Bury
Geoff
McCombe
Anne
Marie
Henihan
Health Services &
Population Health
Research
GEMS, UL
G. McCombe J. Klimas
D. Swan
D. Leahy
Alexandra Cremona
Health Services &
Population Health
Research
GEMS, UL
A Cremona
A Cotter
A Donnelly
C O’Gorman
Daniel
Newman
Dept of Nursing and
Midwifery, UL
P O’Reilly
SH Lee
C Kennedy
Olga
Fagan
Health Services &
Population Health
Research
Health Services &
Population Health
Research
Medical Student, UL
Dr Derek
Forde
AG Stack
Co-Author
9
Co-Author
10
JP Ferguson AG Stack
POSTER PRESENTATION: HEALTH SERVICES & POPULATION HEALTH RESEARCH (continued)
ID
Presentation Title
A38
Dorothy
A qualitative analysis of risk management Dr
and quality improvement strategies for
patients and healthcare professionals in
primary and secondary care.
Pushing hard and fast! An investigation of Mr Eoghan
rate and depth of compressions by trained
responders and practitioners.
Prof Philip
An analysis of the body composition of
patients with Inflammatory Bowel Disease.
Issues concerning the uptake of the
seasonal influenza vaccine by nurses
working in the long-term older person
setting in Ireland’
Development of local area health profiles
for the Republic of Ireland
Hamstring tendon grafting during anterior
cruciate ligament reconstruction. What is
the relationship between pre-operative
and post-operative hamstring strength?
Prevalence of Multimorbidities in Chronic
Pain Patients attending outpatient
Physiotherapy
How physically active are employees at UL
Hospitals Group?
Use of antipsychotics, antidepressants, and
hypnotics/sedatives, in adults with learning
disability: a re-Audit
The comparative effectiveness of exercisebased group and individual physiotherapy
for musculoskeletal conditions: a
systematic review and meta-analysis
A40
A42
A44
A45
A46
A47
A48
A50
A51
Title
Category
Dept /Org
Leahy
Health Services &
Population Health
Research
GEMS
Co-Author 1 Co-Author Co-Author 3 Co-Author 4 Co-Author
2
5
M Culliton
R Shipsey W Cullen
P Finucane J Kennedy
Connolly
Health Services &
Population Health
Research
National Ambulance
Service
Ms B Sinnott Dr N
Cummins
Jakeman
Health Services &
Population Health
Research
UL Body Composition
Study, Human Science
Research Group and 4i
Centre for Interventions
in Infection,
Inflammation and
Immunity, UL
Infection Prevention &
Control Mid West PCCC
L Dowling
D O Donovan L Doherty
Author
M Skelly
C Dunne
Ms
Gemma
Quinn
Health Services &
Population Health
Research
Dr
Marie
Casey
Dept of Public Health
Mr
Colum
Moloney
Health Services &
Population Health
Research
Health Services &
Population Health
Research
Physiotherapy Dept, UHL Dr. K
O’Sullivan
Mr. D
O’Farrell,
Miss Catherine Quinn
Health Services &
Population Health
Research
Physiotherapy Dept, UL
Hospitals – Ennis
Hospital
R Galvin
S O’Higgins L O’Connor
B McGuire
Ms
Maire
Curran
Dept of Physiotherapy ,
UHL
J QuinnMcDonogh
B Moran
H Brady
C Cowan
L Tobin.
Dr
Mary
Kelly
Health Services &
Population Health
Research
Health Services &
Population Health
Research
Daughters of Charity
K Budri
N
Service for Persons with Subramanian
Intellectual Disability
A Yousaf
A Bashir
M Sharif
Ms
Mary
O Keeffe
Health Services &
Population Health
Research
Clinical Therapies, UL
H Purtill
K O’Sullivan
A Hayes
K Mc
Creesh
L Cullen
D Goggin
M O Leary
Dr. A. Clifford
Co-Author
6
Co-Author
7
Co-Author
8
Co-Author
9
Co-Author
10
POSTER PRESENTATION: HEALTH SERVICES & POPULATION HEALTH RESEARCH (continued)
ID
Presentation Title
A52
Ms
Patient-therapist interactions in
musculoskeletal physiotherapy: a
qualitative systematic review and metasynthesis.
Comparative effectiveness of conservative Ms
interventions for non-specific chronic spinal
pain: physical, behavioural or combined? a
systematic review and meta-analysis.
Mary
Screening for Perinatal Mental Illness in an
Antenatal Booking Clinic: An Audit
An Unusual Case of Chlorpromazine Toxicity
in the Emergency Department
An Audit on the Management of Acute
Asthma on Presentation to the Emergency
Department.
Irish Values for Health – A national Study
A53
A54
A55
A56
A58
A59
A60
Title
Category
Dept /Org
O Keeffe
Health Services &
Population Health
Research
Clinical Therapies, UL
Mary
O Keeffe
Health Services &
Population Health
Research
Dr
Mas
Mahady
Mohamad
Dr
Mary
Finnan
Dr
Emer
Leonard
Health Services &
Population Health
Research
Health Services &
Population Health
Research
Health Services &
Population Health
Research
Dr
Roisin
Adams
Assessing the role of a grade 3 general
hospital in diagnosis and management of
colorectal cancer
Implementing dematerialisation strategies Dr
in health services, the importance of interdisciplinary collaboration for scenario
development
Author
Mike
Yvonne
Co-Author 1 Co-Author Co-Author 3 Co-Author 4 Co-Author
2
5
P Cullinane J Hurley
I Leahy
S Bunzli
P
O’Sullivan,
Co-Author
6
K
O’Sullivan
Clinical Therapies, UL
H Purtill
N Kennedy J Hurley
K
O’Sullivan
Dept of Psychiatry
AM Curtin
C Corby
Anaesthesia, UHL
M Finnan
E Leonard
Emergency Dept, UHL
M Finnan
T Moriarty
Health Services &
Population Health
Research
Gorenchtei Health Services &
Population Health
n
Research
National Centre for
Pharmacoeconomics
B Reddy
M Barry
P Kind
GEMS, UL
A Kennedy
C Clancy
E Myers
Ryan
Fogarty
Dept of Chemical and
Dr G Becker
Environmental Sciences,
UL
Health Services &
Population Health
Research
`
Dr B
O’Regan
P O’Sullivan W
Dankaerts
C Walsh
Co-Author
7
Co-Author
8
Co-Author
9
Co-Author
10
POSTER PRESENTATION: LIFESTYLE & HEALTH
Christine
Deasy
Lifestyle & Health
Dept of Nursing and
Midwifery, UL
Co-Author 1 Co-Author Co-Author 3 Co-Author 4 Co-Author
5
2
B Coughlan D Jourdan J Pironom
P MannixMcNamara
Ms
Blathin
Casey
Lifestyle & Health
Clinical Therapies, UL.
B Casey
S Coote
S Hayes
INHALED FOREIGN BODIES IN YOUNG
CHILDREN- A FORGOTTEN HAZARD?
Dr
Muhamma Pathan
d Khan
(MK)
Lifestyle & Health
Paediatrics, UHL
J Twomey
B Linnane
AM Murphy
B06
The direct and indirect associations
between Social Cognitive Theory and
physical activity in people with Multiple
Sclerosis
Dr
Sara
Hayes
Lifestyle & Health
Clinical Therapies, UL
R Motl
S Gallagher S Coote
B07
Sex Differences in Mood Responses to
Acute Aerobic Exercise
Mr
Cillian
McDowell
Lifestyle & Health
Physical Education and
Sport Sciences, UL
M Campbell
MP Herring
B09
Overview of a systematic review of early
detection of noise induced hearing loss in
relation to otoacoustic emissions.
Mr
Nesakuma Tulasi
ran
Lifestyle & Health
Community Audiology
services
B10
Optimisizing patient care through the
Acute Medical Unit with expanded nursing
practice
Marian
Ryan
Lifestyle & Health
AMU UHL Dooradoyle
B11
Ms
A Systematic Review of the Surgical and
Rehabilitative Outcomes of Hip Arthroscopy
in Athletes with Femoroacetabular
Impingement
Danielle
LovettCarter
Lifestyle & Health
GEMS, UL
A Jawanda
A Hennigan
B12
The cellular and molecular consequences of Ms
maternal immune activation on the
development of the rodent spinal cord.
Rebecca
Anderson
Lifestyle & Health
GEMS, UL
RC Anderson FC Clarke
ID
Presentation Title
B02
Predictors of health of pre-registration
nursing and midwifery students: Findings
from a cross sectional survey
B04
Changing Physical Activity Behaviour in
People with Multiple Sclerosis: A Review
B05
Title
Author
Category
Dept /Org
T Foley
Co-Author
6
Co-Author
7
S Gallagher
J Radford
J-M K
GW
Fitzpatrick O’Keeffe
KW
Mcdermott
Co-Author
8
Co-Author
9
Co-Author
10
POSTER PRESENTATION: TECHNOLOGY & HEALTH
ID
Presentation Title
Title
C01
Medical Device Software Process
Improvement: A Perspective from a
Medical Device company
Connected Health: Software, Quality and
Processes
Ms
Marie
Travers
Technology & Health Lero, UL
Dr
Noel
Carroll
Technology & Health ARCH - Applied Research I Richardson
The Influence of Biological Content on the
Fracture Toughness of Femoral Plaque
Tissue
Dr
C07
Hyaluronic Acid Scaffold Coatings for
Diagnostic Applications
Ms
Fernanda
C08
Clinical audit: The appropriate use of CT
pulmonary angiography in patients with
suspected pulmonary embolism
Developing a system wide hospital tool to
inform Hospital escalation status
Ms
Mary Ann Peters
Technology & Health
Dr
Marie
Casey
Technology & Health Dept of Public Health
McNamara,
D
Fitzgerald,
T
Helicopter Emergency Aeromedical Service Mr
Support to the National Ambulance Service,
Ireland: report on a pilot project
Darren
Figgis
Technology & Health Emergency Aeromedical
P Moran
D Gaumont K Henry
P Traynor
D Hennelly C O’Donnell
A Case of Pickwickian Syndrome: Use of An Dr
Extra Corporeal CO2 Removal Device vs.
targeted weight loss therapy
Dr
A New Age of Idiopathic Dilated
Cardiomyopathy: Exploration and
Development of a Genetic Consensus
Case report Endomyocardial fibroelastosis. Dr
Nam
N Yashpal
A O’Brien
S O’Riain
C M Nix
C02
C06
C09
C10
C11
C12
C13
C14
C15
Author
Category
Dept /Org
Co-Author 1 Co-Author Co-Author 3 Co-Author 4 Co-Author
2
5
Dr I
Richardson
Co-Author
6
for Connected Health
Technology Centre, Dept
of CSIS, UL
Eoghan
Cunnane
Technology & Health Centre for Applied
Barrett H.T
Engineering Research,
MSSI, and Mechanical,
Aeronautical &
Biomedical Eng Dept, UL
Characterisation of the functions of Bovine Mr
Serum Albumin in the culture of NS0 cells
producing human therapeutic monoclonal
antibodies
Mr
Validation of the activPAL3 micro
Zamboni
Technology & Health Stokes Laboratories, UL
Kavanagh
E.G
Mongrain R
Walsh M.T
MN Collins
Service, National
Ambulance Service
Yashpal
Technology & Health Dept of Anaesthesia &
S Mahdy
Critical Care, UHL
Cormac
O Connor
Technology & Health Dept of Cardiology, UHL
CT O’Connor ME
D O’Hare
O’Callagha
n
TJ Kiernan
Khalid
Mostafa
Liam
Ahmed
Technology & Health Cardiology Dept, UHL
V.Voon
Prof.
T.Kiernan
L McNamara D Buckley
A.Abbas
U.Azhar
B. Carson
A. Donnelly
Cormac
McNamara Technology & Health Life Sciences/Stokes
Institute
Powell
Technology & Health Dept of Physical
Education and Sport
Sciences, UL
K. Dowd
M Osbourne T Dalton
M.Ayyaz
P Kiely
Co-Author
7
Co-Author
8
Co-Author
9
Co-Author
10
POSTER PRESENTATION: TECHNOLOGY & HEALTH (continued)
ID
Presentation Title
C16
Effectiveness of Age- Adjusted D- Dimers in Mr
Ruling out Pulmonary Embolism
Amritpal
Development of a Quality Performance
Measurement System for a Radiology
Department
Marti
C17
C18
Title
Ms
Author
Jawanda
Category
Dept /Org
Co-Author 1 Co-Author Co-Author 3 Co-Author 4 Co-Author
2
5
Technology & Health UL Graduate Entry
Medical Program
Lotter
Technology & Health Radiology Dept, UHL,
Diagnostic Directorate,
HSE and Lero - the Irish
Software Engineering
Research Centre Dept of
CSIS, UL
Dr Ita
Richardson
Dr Louise
Reid
B. Dunleavy P. O’Byrne
Mr
Turning Data into an Organisational Asset
for Healthcare, This project is about turning
data collected at the point of patient care
into information and knowledge to
monitor, evaluate and plan epilespy
services in Ireland.
Dr
Software Development of Prototype
Colorectal Cancer Database
Michael
Fitzsimons Technology & Health 3rd Year Medical
Student, Graduate Entry
Medicine, UL
M. Dunne
Kevin
Lally
Technology & Health Colorectal Surgery, UHL
C Coffey
C21
Towards the Characterisation of Carotid
Artery Plaque Toughness: An Application
for Cutting Balloon Angioplasty
Hilary
Barrett
Technology & Health Centre for Applied
C22
CORRELATING URETHRAL RUPTURE WITH
DISTENSION OF THE URETHRA DURING THE
INFLATION OF A MISPLACED
TRANSURETHRAL CATHETER BALLOON
C23
Deciphering mechanisms that drive Breast
Cancer Metastasis to Bone
C25
A Preliminary Study to Determine if a
Particular Arteriovenous Fistula
Configuration can Generate Helical Flow in
an Arteriovenous Fistula and if Helical Flow
is a Surrogate Marker of Exposure to
Disturbed Shear
Primary care practitioner’s perspectives on Mr
the challenges for adopting remote patient
technology and its impact for the Irish
Health System
Ms
Central Venous Stenosis associated with
Haemodialysis Access; A Systematic Review
C20
C27
C29
Ms
Co-Author
6
E.M. Cunnane
Biomedical Engineering
Research (CABER), MSSI,
UL
Ms Rachel
Calahane Technology & Health Centre for Applied
Connor V
Engineering Research,
Cunnane
MSSI, and Mechanical,
Aeronautical &
Biomedical Eng Dept, UL
Ms Anushree Dwivedi Technology & Health Dept. of life Sciences,
D Hoey,
Faculty Of Science and
Engineering Technology & Health Dept of Mechanical,
Mr Connor
Cunnane
Aeronautical &
Biomedical Eng, UL
Myles
Gardiner
Technology & Health E-Health Three Ireland
M,Gardiner
Sinead
Morley
Technology & Health MABE, UL
D Newport
Dr Bryan
Kenny
M.
Fitzsimons
N. Delanty
John A
Thornhill
E.G.
Kavanagh
M.T. Walsh
Niall F
Davis
Eoghan M
Cunnane
Rory O’C
Mooney
S Broderick
M Walsh
P A Kiely
L Browne
M Walsh
Michael T
Walsh
Co-Author
7
Co-Author
8
Co-Author
9
Co-Author
10
POSTER PRESENTATION: CLINICAL RESEARCH
Author
Category
Dept /Org
Ryan
Clinical Research
Respiratory Dept, ULHG.
Co-Author 1 Co-Author Co-Author 3 Co-Author 4 Co-Author
2
5
Ryan, P
O’Brien, A Casserly, B
William
Anthony
Moynihan
Clinical Research
X-RAY DEPT, UHL
L Bowden
Mr.
Hal
Cavus
Clinical Research
Dept of Psychology,
Education and Health
Sciences, UL
R M Msetfi
Dr
Hamid
Yousuf
Clinical Research
Gastroenterology, UHL
U sharif
A Sulaiman I ul Haq
Mr
Ronan
Callanan
Clinical Research
Year 4 Medical Student,
UL GEMS
D Ryan
L Hickey
Ms
Sanskriti
Sasikumar Clinical Research
Medical Student,
ULGraduate Entry
Medicine
Iain Feeley
MBBS MRCS
Dorathy
Niall MBBS
MCh FRCS
Mrs
Maura
Cleary
Clinical Research
Physiotherapy
F Steed
J Saunders
ID
Presentation Title
Title
D02
Adherence to Long Term Oxygen Therapy
for Chronic Obstructive Pulmonary Disease
patient’s in the HSE mid-western area.
A comparison of Test Bolus at 100 KVP
versus Bolus Tracking at 120 KVP of
Multidetector CT Pulmonary Angiography
protocols (CTPA) in a 64 slice scanner.
Judgements of contingency under cognitive
load: The role of available cognitive
capacity in feelings of control, learned
helplessness and hopelessness
Adequacy of bowel preparation in patients
undergoing inpatient and outpatient
colonoscopy: Results of a single center
audit
A retrospective cohort study on the
suitability of the empirical antibiotic
treatment of sepsis in University Hospital
Limerick Emergency Department.
Does knee flexion in the post operative
period following total knee arthroplasty
reduce blood loss resulting from the
procedure: A systematic review of the
literature
Multifactorial Falls Prevention programme,
A Collaboration between UL Hospitals,
Nenagh Hospital and Network 9 PCCC
Ms
Paula
Mr
D03
D04
D05
D06
D07
D08
P Kiely
Co-Author
6
JM O Brien
M Ahmed
M Skelly
D09
Rivaroxaban- A cost effective alternative to Prof Michael
Warfarin in the treatment of provoked DVT.
Watts
Clinical Research
Dept. Medicine, UHL
Emma
Groarke
William
Courtney
Jane Conway Deborah
Burke
Jean
Saunders
Denis
O’Keeffe
D10
TREATMENT FREE REMISSION IN CHRONIC
MYELOID LEUKAEMIA - A NEW GOAL: IS
THIS POSSIBLE IN IRELAND (ROI)?
Groarke
Clinical Research
Dept of Haematology,
UHL
EM Groarke
S
Langabeer
D O’Keeffe
M Leahy
M Ryan
Dr
Emma
H O’Leary
Co-Author
7
Co-Author
8
Co-Author
9
Co-Author
10
POSTER PRESENTATION: CLINICAL RESEARCH (continued)
Co-Author 1 Co-Author Co-Author 3 Co-Author 4 Co-Author
5
2
E Groarke
L O'Brien
M Kiely
S Joyce
J Gleeson
Co-Author
6
H O’Leary
Dept of Haematology,
UHL
Emma
Groarke
Tariq
Joanne Nally Maeve Leahy Hilary
Mohamme
O'Leary
d Abkur
Denis
O’Keeffe
1. Rheumatology Dept,
UHL, Limerick 2.GEMS,
Limerick
1. Rheumatology Dept,
UHL, Limerick
2. GEMS, Limerick
Fahd Adeeb
Wan Lin
Austin Stack Joe Devlin
Fahd Adeeb
Shakeel
Anjum
Philip
Hodnett
Clinical Research
1. Rheumatology Dept,
UHL, Limerick
2. GEMS, Limerick
Fahd Adeeb
Conall WR Conrad V
Fitzgerald Timon
Coughlan
Clinical Research
Dept of Cardiology, UHL
JJ Coughlan
H Yagoub
Prof T
Kiernan
Miss Ceara
Rice
Clinical Research
H
O’Connell
Mr
Cullinane
Clinical Research
Mrs Berbie
Swelling, Erythema and Induration in the
Genitalia of Pediatric Patients?
Think of Metastatic Crohn’s Disease –Delay
in diagnosis can cause significant morbidity
Byrne
Clinical Research
4th year medical student, M Leonard
presenting on behalf of
the Psychiatry Research
Dept UL
Dept of Clinical
M O’Keeffe
Therapies, Faculty of
Education & Health
Sciences, UL, Limerick,
Ireland Dermatology Dept, UHL M Lynch
CLOGGED UP!
Wong
Clinical Research
Dept of Medicine, UL
Group of Hospitals (St
John’s Hospital,
Limerick)
CEARA RICE
ID
Presentation Title
Category
Dept /Org
D11
Dr
STREAMLINING THE MANAGEMENT OF
BLOOD GROUP O RH NEGATIVE BLOOD
STOCK: A SINGLE CENTRE IRISH EXPERIENCE
Dr
FIVE CASES OF PNEUMOCYSTIS
PNEUMONIA (PCP) INFECTION IN PATIENTS
FOLLOWING TREATMENT WITH
BENDAMUSTINE / RITUXIMAB:
PROPHYLAXIS SHOULD BE CONSIDERED AS
STANDARD PRACTICE
Behcet's disease in Ireland: Patient Access Dr
and Response to Biologics
Emma
Groarke
Clinical Research
Dept of Haematology,
UHL
Emma
Groarke
Clinical Research
Fahd
Adeeb
Clinical Research
Dr
Resolution of Deep Variant Morphea
(Morphea Profunda): A case series of three
patients successfully treated with
Abatacept (Orencia)
SIGNIFICANT LARYNGEAL DESTRUCTION IN Dr
A NORTHERN EUROPEAN COHORT OF
BEHÇET’S DISEASE PATIENTS
Fahd
Adeeb
Clinical Research
Fahd
Adeeb
PPCI with large volume thrombus burden:
The Angiojet Experience at UHL
Performance on a Novel Test of Attention
(‘The Lighthouse Test’) Amongst Elderly
Medical Outpatient Attendees
Dr
JJ
D18
Measuring Physiotherapist’s Verbal
Communication During a Chronic Low Back
Pain Consultation: A Cross-Sectional
Observational Study
D19
D20
D12
D13
D14
D15
D16
D17
Title
Dr
Author
Paul
Eleanor
EITHNE
MULLOY
Joe Devlin
Alexander
Duncan
Fraser
Alexander
Duncan
Fraser
Neville P
Shine
Joseph P
Hughes
Alexander
D Fraser1
C Exton
M Melville
C Dunne
D Meagher
D Wall
K Ahmed
B Ramsay
K
O’Sullivan
L Roche
Co-Author
7
Co-Author
8
Co-Author
9
Co-Author
10
POSTER PRESENTATION: CLINICAL RESEARCH (continued)
ID
Presentation Title
Title
D21
Development of a Novel Test of
Visuospatial Cognition: The Letter and
Shape Drawing Test. A study of
performance in Hospitalised Elderly
Patients and Young Healthy Adults
An Audit of Paediatric Service Utilisation in
Primary Care by Funding Scheme
Radiation Doses from Radiological
Investigations: Is there a need for formal
education?
The context, causes and consequences of
falls in people with Multiple Sclerosis:
Preliminary results from an Irish crosssectional study
Renal Infarction Secondary To Spontaneous
Renal Artery Dissection: A Case Report
Dr
Debbie
Mr
D22
D23
D25
D26
D27
D28
D29
D30
D31
Prevalence of significant hepatic fibrosis
and cirrhosis assessed by the NAFLD
Fibrosis Score in patients attending the
diabetic clinic
One-Stage V s Two-Stage Brachio-Basilic
Arteriovenous Fistula for Dialysis: A
Systematic Review and a Meta-Analysis
Role of Far Infra-Red therapy in dialysis
Arterio-venous Fistula maturation and
survival: Systematic review and metaanalysis
Effects of neck radiation therapy on extracranial carotid arteries atherosclerosis
disease prevalence: Systematic Review and
a Meta-analysis
The use of arteriovenous fistulae as an
adjunct to peripheral arterial bypass: A
systematic review and meta-analysis.
Co-Author 1 Co-Author Co-Author 3 Co-Author 4 Co-Author Co-Author
5
6
2
D Adamis
A Hannigan CP Dunne
OA Williams M Leonard C Exton
Category
Dept /Org
White
Clinical Research
Dept of Anaesthetics,
University Hospital
Galway
Bradley
Taylor
Clinical Research
UL – GEMS
Dr
Cormac
O Connor
Clinical Research
C/O Ms Nuala Lynch, HSE Bowden L
West
Lynch N
O’Brien J
Ms
Laura
Comber
Clinical Research
Dept of Clinical
Therapies UL
L Comber
R Galvin
S Coote
Mr
Zeshan
Siddiqui
Clinical Research
Y4 Medicine, GEMS UL
Wu Z
Siddiqui Z
Smith C
Mr
Zeshan
Siddiqui
Clinical Research
Y4 Medicine, GEMS UL
Chin JL
Chan G
Sin PS
Mr
Khalid
Bashar
Clinical Research
Dept of Vascular Surgery, D. A. Healy
UHL
Mr
Khalid
Bashar
Clinical Research
Mr
Khalid
Bashar
Mr
Thomas
Aherne
Author
Taylor B
Co-Author Co-Author
8
7
D Meagher
Morrissey
P
Siddiqui Z
O’Rathallai Aftab A
gh E
Courtney G McGurk C
S. Elsheikh L.D. Browne
M.T. Walsh
M.Clarke – P.E. Burke
Moloney
E. G.
Kavanagh
Dept of Vascular Surgery, L.D. Browne
UHL
E. A. H.
M.T. Walsh
Kheirelseid
M.Clarke –
Moloney
P.E. Burke
S.R. Walsh
Clinical Research
Dept of Vascular Surgery, D.Healy
UHL
M.ClarkeMoloney
P.Burke
E.Kavanagh
S.R. Walsh
Clinical Research
Dept of Vascular Surgery, T. Maloney
UHL
P. Burke
E Kavanagh
P. Naughton
E.G.
Kavanagh
S.R. Walsh
Co-Author
9
Co-Author
10
POSTER PRESENTATION: CLINICAL RESEARCH (continued)
ID
Presentation Title
Category
Dept /Org
D33
Ms
Sonographic features of thyroid nodules;
diagnostic accuracy.
Ms
Thyroid FNA guidelines; a comparison of
the six international recognised guidelines.
Arlene
Weir
Clinical Research
GEMS, UL.
Arlene
Weir
Clinical Research
GEMS, UL.
Dr. Declan
Sheppard
An audit of MRI lumbar spine for detection Dr
of suspected Cauda Equina Syndrome.
A comparison of carotid and femoral arterial Dr
plaque composition and correlation with
clinical details for consecutive patients that
underwent endarterectomy at University
Hospital Limerick 2012-2014
Padraig
Kelly
Clinical Research
Sligo General Hospital
P Hession
Mairead
Hennessy
Clinical Research
Dept of Vascular Surgery, MM
UHL
Hennessy
EM
Cunnane
EG Kavanagh MT Walsh
Carotid Endarterectomy – a single centre
experience
The effects of a group Shoulder Exercise
Class: a qualitative and quantitative
evaluation
5-α-Reductase Deficiency in Two Siblings: A
Case Report
Cork City Marathon Research Study
Mr
Adeel
Zafar
Syed
Clinical Research
Vascular Surgery, UHL
Zafar A
Boyle E
Gowey A
Dr
Karen
McCreesh
Clinical Research
Dept of Clincial
Therapies
Hayes A
Conroy C
Kelleher M
Ms
Ivana
Capin
Clinical Research
GEMS UL
Dr. M Ryan
Mr
Cian
O Brien
Clinical Research
Dept. of Epidemiology &
Public Health UCC
Prof. John
Browne
Dr. Niamh
Cummins
D41
An outbreak of extended spectrum betalactamase-resistant Escherichia coli in an
Irish neonatal intensive care unit.
Dr
Ciara
O Connor
Clinical Research
D42
Dr
A case of infective endocarditis in endstage kidney disease mediated by
daptomycin-resistant, vancomycin-resistant
enterococci.
Mr.
DERIVATION OF THE CT HEAD RULE FOR
EMERGENCY DEPARTMENT SYNCOPE
PATIENTS
Ciara
O Connor
Clinical Research
Clinical Microbiology
C O’Connor
Specialist Registrar, Dept
of Clinical Microbiology,
UHL.
Clinical Microbiology
C O’Connor
Specialist Registrar, Dept
of Clinical Microbiology,
UHL.
Dr.
AnneMarie
O’Flynn
R Philip
J.
Viau (BA,
Alexander MA)
Clinical Research
D34
D35
D36
D37
D38
D39
D40
D43
Title
Author
Co-Author 1 Co-Author Co-Author 3 Co-Author 4 Co-Author
2
5
Dr. Declan
Sheppard
P Boers
R Philip
LF Casserly L Power
Graduate Entry Medicine M Mukarram K Arcot
School, UL (2 nd year)
Co-Author
6
Dr. V
Thiruganasa
mbandamoor
thy
Abdularahim Kavanagh E Burke P
O
L Power
NH
O’Connell
CP Dunne
C Finnegan
NH
O’Connell
CP Dunne
Co-Author
7
Co-Author
8
Co-Author
9
Co-Author
10
POSTER PRESENTATION: CLINICAL RESEARCH (continued)
Co-Author 1 Co-Author Co-Author 3 Co-Author 4 Co-Author
5
2
Shack, M
Ryan, D
Co-Author
6
GEMS, UL S.M.
Sahebally
P.N. Faul
P.A. Kiely
Clinical Research
GEMS, UL
H O’Driscoll
G MC
Cormack
Kinsella
Clinical Research
GEMS student
Austin G.
Stack
Eimear
O Neill
Clinical Research
UHL, 4th year Graduate
entry into Medicine, UL
Ms
Gillian
Quinn
Clinical Research
Physiotherapy Dept, St. Dr. S. Coote
Vincent’s University
Hospital, Dublin, Clinical
Therapies Dept, UL
Cormac
O Connor
Clinical Research
Dept of Cardiology, UHL CT O’Connor M
TJ Kiernan
Gorenchtei
n
Karen
McCreesh
Clinical Research
Dept of Clinical
Therapies, UL
E Barrett
D52
Through the Looking Glass: The Integration Dr
of Intracoronary Optical Coherence
Tomography in an Irish Tertiary referral
Centre
Dr
Is Thoracic Spine Posture Associated with
Shoulder Pain, Range of Motion and
Function? A Systematic Review.
Dr
Get SMART, Write it Down!
Ari
Damla
Clinical Research
UHL, Urology Intern
D Ryan
D53
Audit of Radiological Investigation of Renal Dr
Ari
Damla
Clinical Research
UHL, Urology Intern
D Ryan
Cliodhna
Ni
Mhurchu
Clinical Research
UL GEMS
ID
Presentation Title
Title
D44
An Audit of Venothromboembolism
Prophylaxis in Lower Limb Immobalisation
Relationship of mesenteric disease
manifestations in Crohn's disease with
mucosal and systemic manifestations. Retrospective Audit of the Utilization of
Infliximab in Inflammatory Bowel Disease
Patients at a Single Centre over a 10-year
Period
Prevalence and correlations of
Inappropriate Prescribing Practice (PIP) in
Chronic Kidney Disease; a Multi-Centre Irish
study
Anti-coagulation: A study of the
prescription preferences of general
practitioners and an audit comparing the
usage of novel anti-coagulant drugs versus
warfarin in the primary care setting.
Assessing the Predictive Validity of the
TUG, Timed Up and Go test, and a
Questionnaire to Determine the Risk of
Falling in People with Multiple Sclerosis.
Ms
D45
D46
D47
D48
D49
D50
D51
D54
Colic in UHL ED Department
Carbon monoxide toxicity as a primary or
contributory cause of death: an
observational study of cases in forensic
medicine.
Author
Category
Dept /Org
Shack
Clinical Research
UL, GEMS
Miss Miranda
Kiernan
Clinical Research
Miss Hannah
O Driscoll
Mr
Michael
Ms
Melissa
F. Shanahan C. Dunne J.C.
Coffey Mohamed
E. Elsayed
Muhammad Sibéal Nic
Umair Sharif Suibhne
John
Ferguson
L. Comber
Dr. C.
McGuigan
M O’ Keeffe K O’ Sullivan K McCreesh
J Lewis
Co-Author
7
Co-Author
8
Co-Author
9
Co-Author
10
POSTER PRESENTATION: CLINICAL RESEARCH (continued)
ID
Presentation Title
Title
D55
Case Series of Patients Diagnosed With
Cervicogenic Vertigo – an unfamiliar
complaint.
Outcomes for patients with CIN 11 and CIN
111 treated with Cold Coagulation
Audit of VTE thromboprophylaxis in UHL
and development of a VTE audit tool.
Pharmacist contribution to a new oral
anticancer medication (OAM) clinic
IMPAIRED NITRIC OXIDE MEDIATED
VASODILATION IN LACUNAR STROKE
Exploring the benefits of oral protein
supplementation in gastrointestinal surgery
patients: a systematic review
Characterising the role of Protein Kinase C
in Breast Cancer
Nurses experience of supporting patients
with a tracheostomy a descriptive
qualitative enquiry.
Circulating fibrocyte levels in patients preand post-operation.
Correlating the expression of Protein
Kinase C isozymes with the transformed
phenotype in Colorectal Cancer
Deciphering the role of RACK1 in regulating
MAP Kinase Activity to promote
proliferation in Colorectal Cancer
Potential role of ultrasound examination in
the diagnosis of neonatal fractures
A one year follow up and case study, for
Faecal Transplant in the Management of
Crohn's Colitis with persistent Clostridium
Difficile Infection.
A retrospective comparison of focused
versus Standard Abdominopelvic CT
examination in the evaluation of patients
with suspected abdominal and pelvic
disease.
A Case of Idiopathic Primary Pulmonary
Hypertension in an 18 year old female,
managed at the Acute Medical Assessment
Unit at Ennis General Hospital.
Miss Ciara
D56
D57
D60
D61
D62
D63
D64
D65
D66
D67
D68
D69
D70
D71
Author
Category
Dept /Org
Hennessy
Clinical Research
UHL– Ear, Nose and
Throat Dept. GEMS.
Maureen
Madden
Clinical Research
Colposcopy Clinic
L Hartigan
A Sultan
G Reidy
K Hickey
Mr
Eoin
Barrett
Clinical Research
Dept of Pharmacy UHL
E Barrett
S Nic
Suibhne
A M Ali
B McGee
B Stack
M Aherne
Ms
Michelle
English
Clinical Research
Pharmacy Dept, UHL.
O Flynn
Dr
Elaine
Shanahan
Clinical Research
Dept of Therapeutics and P Guilfoyle
Aging,
G Burke
S H Haider
, E Moloney
H Markus
S Jackson
Mr
Mike
Crickmer
Clinical Research
GEMS – UL
Coffey, J.C
Dunne, S.
Dr
Mary
McCumiske Clinical Research
y
Dept. of Life Sciences, UL C.M. Dowling A. Merrigan A. Lal
S. Tormey
T. Dalton
Ms
Jane
Savage
Clinical Research
ENT DEPT, UHL
Miss Funke
Owolabi
Clinical Research
GEMS, UL
Ms
Dowling
Clinical Research
Dept of Life Sciences, and
MSSI, UL, Limerick
Miss Sheri
Hayes
Clinical Research
Department of Life
Sciences, UL
Catrìona
Dowling
Dr
Jim
Crotty
Clinical Research
Dept of Radiology, UHL
R. Coakley
Dr
Donal
Cahill
Clinical Research
Medical SHO, UHL
Dr M
Moloney
Dr
Donal
Cahill
Clinical Research
Medical SHO, UHL
Dr J Crotty
Dr
Donal
Cahill
Clinical Research
Medical SHO, UHL
Dr S
Gerraghty
Catríona
M
Co-Author 1 Co-Author Co-Author 3 Co-Author 4 Co-Author
2
5
C O’Rourke J.E Fenton.
Crickmer, M Dunne, C.P O’Regan, A
M.G. Kiernan P Tibbits
Patrick A
Kiely
Dr T Perice
J.C. Coffey
Co-Author
6
P.A. Kiely
Co-Author
7
Co-Author
8
Co-Author
9
L Kalra
C Swift
D Lyons
Co-Author
10
POSTER PRESENTATION: CLINICAL RESEARCH (continued)
ID
Presentation Title
D72
THE VALUE OF ROUTINE CXRs PERFORMED Dr.
IN YOUNG CHILDREN WITH CYSTIC FIBROSIS
Ngozi
Oketah
D73
Bone age assessment in General Paediatric
Practice.
Is RACK1 able to modulate the translation
elongation in cancer?
Pain and depressive symptoms in an
inpatient palliative care setting: do they
overlap?
Education and Training at UL Hospitals – the
NCHD perspective
Immediate response of the supraspinatus
tendon to loading in rotator cuff
tendinopathy
CLINICAL SIGNIFICANCE OF RAISED
HAEMATOCRIT LEVELS IN A SINGLE
READING: AN APPROACH TO DETERMINING
NECESSARY FOLLOW UP
Continuous Infusion Ondansetron for the
Management of Nausea & Vomiting in
Patients Receiving Cisplatin
Vitamin D, serotonin regulation and its
potential relevance in seasonal affective
disorder:A Review
Use of the clock drawing test (CDT) for
identification and assessment of Delirium
in hospitalised patients: a systematic
review.
10-year experience of acetabular
reconstruction using trabecular metal
Delirium in Palliative Care: Investigating the
relationship between delirium specific
diagnostic features and various cognitive
domains
Dr
Mark
O´Rahelly Clinical Research
Intern UHL
Ms
Beatrice
Malacrida Clinical Research
Dept. of Life Sciences and CM Dowling PA Kiely
MSSI, UL, Limerick
Dr
Mas
Mahady
Mohamad
Clinical Research
Cognitive Impairment
Research Group, GEMS
B Davis
M Leonard , F Twomey
M Lucey
M Conroy
Prof Paul
Finucane
Clinical Research
Chief Academic Officer,
UL Hospitals
E Jennings
N Lynch
J O’Connor
D O’Hare
L Rafter
Dr
Karen
McCreesh
Clinical Research
Dept of Clincial
Therapies
Donnelly AE
Lewis JS
Dr
Adrian
Maraj
Clinical Research
Dept of Haematology,
UHL
EM Groarke
C Lenihan
M Leahy
H O'Leary
D O'Keeffe
Ms
Mary Rose Pambid
Clinical Research
Medicine, UL
B. Baadjes
J.E. Potts
R. Esau
S.R. Rassekh
Mr
Adam
Clinical Research
GEMS
Dr
Olugbenga Williams
Clinical Research
Cognitive Impairment
Research Group, UL
GEMS
H O’Connell
M Leonard D Adamis
Gorenchtei Clinical Research
n
GEMS, UL
FE Rowan
F Condon
Davis
Cognitive Impairment
M Mohamad M Leonard M Lucey
Research Group (CIRG),
Dept of Psychiatry, GEMS
(GEMS).
D74
D75
D76
D77
D78
D79
D80
D81
D82
D83
Title
Author
Mike
Miss Brid
O Brien
Category
Dept /Org
Clinical Research
Paediatric Respiratory
Dept. UHL
Clinical Research
Co-Author 1 Co-Author Co-Author 3 Co-Author 4 Co-Author
2
5
D.T. McHugh N. Power
C. Lynch
B. Linnane
N Bussmann B Jamal,
Co-Author
6
Co-Author
7
K Ryan
D Meagher
AM Murphy
D Meagher
F Twomey
M Conroy
D Meagher
Co-Author
8
Co-Author
9
Co-Author
10
POSTER PRESENTATION: CLINICAL RESEARCH (continued)
ID
Presentation Title
Title
D84
A study of depressive symptoms in
hospitalised elderly medical patients with
and without neurocognitive disorders
An Audit of Preoperative Fasting in UHL
Dr
Mas
Mahady
Mohamad
Dr
Cathal
MacDonnc Clinical Research
ha
Anaesthesia, University
Hospital Galway
Title: Development of an abbreviated
version of the Cornell Scale for Depression
in Dementia (CSDD) for use in detection of
depressive illness in elderly hospitalized
patients.
Severity of Sleep Apnea in the Obese
Population: Does Hypoventilation
Syndrome make a Difference
Geriatric Urology:an evolving subspeciality
with increasing workload
Is testicular pain and vomiting
pathognomonic for testicular torsion in
pubertal boys? Implications for lay and
medical education.
Case series , development of second
malignancies after receiving Bortezomib for
Multiple Myeloma
Dr
Ahmed
Abba Aji
Clinical Research
Adult Mental Health
Services
Dr
Tyler
Hynes
Clinical Research
Dr
Joana
Leao
Mr
Dr
D85
D86
D88
D89
D90
D91
Author
Category
Dept /Org
Clinical Research
Cognitive Impairment
Research Group, GEMS
Co-Author 1 Co-Author Co-Author 3 Co-Author 4 Co-Author
2
5
M Leonard
J
S McInerney M O’Connor BA Davis
McFarland
J O’Dea
N
Kiernan–McC
onnell
Henry
David
O’Connell
J.Meagher
Paul
Reynolds
Dept of Respiratory
Medicine
Chong SC
Saleem S.
Casserly B
Clinical Research
Dept of Urology
Francis S
Aslam A
Flood HD
Asadullah Aslam
Clinical research
Dept of Urology
Kelly NP
Domanska Giri SK
K
Mohamed Mohamed
Bakri
Clinical research
Dept of Haematology,
UHL
Dr. MR Ryan Dr. H
O’Leary
Mas
Mohamad
Giri SK
Flood HD
Co-Author Co-Author Co-Author
6
7
8
P Reynolds AM Meaney D Adamis
Anna Maria Alaba
Meaney
Olugbenga
Williams
Co-Author
9
C Condon
Co-Author
10
C Dunne